ras GTPase-activating protein nGAP isoform X8

Overview


Name	ras GTPase-activating protein nGAP isoform X8
Smed ID	SMED30017175
Length (bp)	4815

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of ras GTPase-activating protein nGAP isoform X8 (SMED30017175) t-SNE clustered cells

Violin plots show distribution of expression levels for ras GTPase-activating protein nGAP isoform X8 (SMED30017175) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ras GTPase-activating protein nGAP isoform X8 (SMED30017175) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017175

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Category 4 cell	SMED30017175	h1SMcG0022641	dd_Smed_v4_6499_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294])

HSP 1 Score: 332.028 bits (850), Expect = 3.454e-94
Identity = 194/494 (39.27%), Postives = 274/494 (55.47%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ I +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S + L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   91 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SAADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 505

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294])

HSP 1 Score: 332.028 bits (850), Expect = 3.564e-94
Identity = 194/494 (39.27%), Postives = 274/494 (55.47%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ I +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S + L E                    Q +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   58 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SAADLPE-------------------HQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 472

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294])

HSP 1 Score: 332.028 bits (850), Expect = 7.453e-94
Identity = 194/494 (39.27%), Postives = 274/494 (55.47%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ I +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S + L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  154 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SAADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 568

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294])

HSP 1 Score: 332.028 bits (850), Expect = 8.409e-94
Identity = 194/494 (39.27%), Postives = 274/494 (55.47%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT K  TD +FWGE F   +L  + TVT+ L++ +     KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ I +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S + L E                    Q +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  121 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDK---KKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SAADLPE-------------------HQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 535

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Human
Match: DAB2IP (DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294])

HSP 1 Score: 332.798 bits (852), Expect = 1.027e-93
Identity = 194/494 (39.27%), Postives = 274/494 (55.47%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ I +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S + L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  182 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SAADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5])

HSP 1 Score: 340.117 bits (871), Expect = 2.824e-98
Identity = 201/521 (38.58%), Postives = 305/521 (58.54%), Query Frame = 3

Query: 1305 LLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKE 2867
            L +  +SC +  ER KW+  L + + P    +RR E S+ +WI EAK +P K++Y+CE+ LD+TL+AKT++K  TD +FWGE F    L +++ V + L++ S    +KKKK    LI  V I    +S+R+ VERWY  + S++ SGT                            + ++ +    S+S   P +RIKAR+Q++ +LP+  Y +LLE L  + + L  +++  L V++KEDLA SL+ V++K  +A EFL DL+ +E++K DN++++ RGNT+A+KA+E ++KL+ + YL   LSDF+  + Q ++ CEVDPQ  K    SNSSL + ++L                   LM  V++ W KIL++    P+ L+ VF +LR RLE  +R A         L + ++SS IFLRF+CPAIL+PSLF L+ EYP +P   R  TL+AK +Q+LANFS   G KE +M FMN F++ ++  M+ FL  ISS +    S  + N  + VDA KE
Sbjct:   99 LASTYYSCRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESD---SKKKKDT--LIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGT----------------------------SRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQ--KLGNVSNSSLEKNRAL-------------------LMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA---------LADTLISSSIFLRFLCPAILSPSLFNLVSEYP-SPTNARNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESK---SGPEKNADAIVDAGKE 551

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5])

HSP 1 Score: 340.117 bits (871), Expect = 3.323e-98
Identity = 201/521 (38.58%), Postives = 305/521 (58.54%), Query Frame = 3

Query: 1305 LLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKE 2867
            L +  +SC +  ER KW+  L + + P    +RR E S+ +WI EAK +P K++Y+CE+ LD+TL+AKT++K  TD +FWGE F    L +++ V + L++ S    +KKKK    LI  V I    +S+R+ VERWY  + S++ SGT                            + ++ +    S+S   P +RIKAR+Q++ +LP+  Y +LLE L  + + L  +++  L V++KEDLA SL+ V++K  +A EFL DL+ +E++K DN++++ RGNT+A+KA+E ++KL+ + YL   LSDF+  + Q ++ CEVDPQ  K    SNSSL + ++L                   LM  V++ W KIL++    P+ L+ VF +LR RLE  +R A         L + ++SS IFLRF+CPAIL+PSLF L+ EYP +P   R  TL+AK +Q+LANFS   G KE +M FMN F++ ++  M+ FL  ISS +    S  + N  + VDA KE
Sbjct:  107 LASTYYSCRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESD---SKKKKDT--LIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGT----------------------------SRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQ--KLGNVSNSSLEKNRAL-------------------LMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA---------LADTLISSSIFLRFLCPAILSPSLFNLVSEYP-SPTNARNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESK---SGPEKNADAIVDAGKE 559

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5])

HSP 1 Score: 341.273 bits (874), Expect = 7.274e-98
Identity = 201/521 (38.58%), Postives = 305/521 (58.54%), Query Frame = 3

Query: 1305 LLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKE 2867
            L +  +SC +  ER KW+  L + + P    +RR E S+ +WI EAK +P K++Y+CE+ LD+TL+AKT++K  TD +FWGE F    L +++ V + L++ S    +KKKK    LI  V I    +S+R+ VERWY  + S++ SGT                            + ++ +    S+S   P +RIKAR+Q++ +LP+  Y +LLE L  + + L  +++  L V++KEDLA SL+ V++K  +A EFL DL+ +E++K DN++++ RGNT+A+KA+E ++KL+ + YL   LSDF+  + Q ++ CEVDPQ  K    SNSSL + ++L                   LM  V++ W KIL++    P+ L+ VF +LR RLE  +R A         L + ++SS IFLRF+CPAIL+PSLF L+ EYP +P   R  TL+AK +Q+LANFS   G KE +M FMN F++ ++  M+ FL  ISS +    S  + N  + VDA KE
Sbjct:  199 LASTYYSCRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESD---SKKKKDT--LIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGT----------------------------SRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQ--KLGNVSNSSLEKNRAL-------------------LMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA---------LADTLISSSIFLRFLCPAILSPSLFNLVSEYP-SPTNARNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESK---SGPEKNADAIVDAGKE 651

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5])

HSP 1 Score: 341.273 bits (874), Expect = 1.360e-97
Identity = 201/521 (38.58%), Postives = 305/521 (58.54%), Query Frame = 3

Query: 1305 LLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKE 2867
            L +  +SC +  ER KW+  L + + P    +RR E S+ +WI EAK +P K++Y+CE+ LD+TL+AKT++K  TD +FWGE F    L +++ V + L++ S    +KKKK    LI  V I    +S+R+ VERWY  + S++ SGT                            + ++ +    S+S   P +RIKAR+Q++ +LP+  Y +LLE L  + + L  +++  L V++KEDLA SL+ V++K  +A EFL DL+ +E++K DN++++ RGNT+A+KA+E ++KL+ + YL   LSDF+  + Q ++ CEVDPQ  K    SNSSL + ++L                   LM  V++ W KIL++    P+ L+ VF +LR RLE  +R A         L + ++SS IFLRF+CPAIL+PSLF L+ EYP +P   R  TL+AK +Q+LANFS   G KE +M FMN F++ ++  M+ FL  ISS +    S  + N  + VDA KE
Sbjct:  239 LASTYYSCRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESD---SKKKKDT--LIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGT----------------------------SRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQ--KLGNVSNSSLEKNRAL-------------------LMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA---------LADTLISSSIFLRFLCPAILSPSLFNLVSEYP-SPTNARNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESK---SGPEKNADAIVDAGKE 691

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Celegans
Match: gap-2 (Ras GTPase-activating protein gap-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MLZ5])

HSP 1 Score: 341.658 bits (875), Expect = 2.090e-97
Identity = 201/521 (38.58%), Postives = 305/521 (58.54%), Query Frame = 3

Query: 1305 LLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKE 2867
            L +  +SC +  ER KW+  L + + P    +RR E S+ +WI EAK +P K++Y+CE+ LD+TL+AKT++K  TD +FWGE F    L +++ V + L++ S    +KKKK    LI  V I    +S+R+ VERWY  + S++ SGT                            + ++ +    S+S   P +RIKAR+Q++ +LP+  Y +LLE L  + + L  +++  L V++KEDLA SL+ V++K  +A EFL DL+ +E++K DN++++ RGNT+A+KA+E ++KL+ + YL   LSDF+  + Q ++ CEVDPQ  K    SNSSL + ++L                   LM  V++ W KIL++    P+ L+ VF +LR RLE  +R A         L + ++SS IFLRF+CPAIL+PSLF L+ EYP +P   R  TL+AK +Q+LANFS   G KE +M FMN F++ ++  M+ FL  ISS +    S  + N  + VDA KE
Sbjct:  288 LASTYYSCRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESD---SKKKKDT--LIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGT----------------------------SRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQ--KLGNVSNSSLEKNRAL-------------------LMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA---------LADTLISSSIFLRFLCPAILSPSLFNLVSEYP-SPTNARNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESK---SGPEKNADAIVDAGKE 740

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0302836)

HSP 1 Score: 315.849 bits (808), Expect = 4.160e-87
Identity = 168/494 (34.01%), Postives = 279/494 (56.48%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISS 2801
            +SC S  ER  W+  L + + PN ++ RR + SL +W+ EAKN+P KKRYFCE+ LD+TL+ +T+ K  TDLLFWGE F+   + ++N +T+ +++   +   KKK+ ++  +  V I   D+++R   E+WYP     + +G  +                                 +   + + LP +RIK R+Q+ D+LPIN Y + L +LK++  ++   ++  + VK KED+  +L+ ++H QG+A  FL+D++  ++ +  ++ +  RGN++A+K++E +LKL GE+YL   LS  +N + Q + DCEVDP ++     S SS    Q                ++Q +L   V   W  I  S  +FP +L++ F + R+RL+Q+ R          ++ + ++S+ IFLRF+CPAIL+PSLF +  E P + +  R  TLVAK +Q+LANF+   G KE++M F+N F+E +   MQ FL+ IS+
Sbjct:  274 YSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFR---EVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYP--ILSDKAGDSL-------------------------GRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKT-----SGSSAGSLQ----------------RQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR---------QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRFQG-KENFMEFLNDFLEQEAARMQQFLEIIST 705

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0340629)

HSP 1 Score: 315.464 bits (807), Expect = 5.179e-87
Identity = 169/495 (34.14%), Postives = 280/495 (56.57%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMN-VDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISS 2801
            +SC S  ER  W+  L + + PN ++ RR + SL +W+ EAKN+P KKRYFCE+ LD+TL+ +T+ K  TDLLFWGE F+   + ++N +T+ +++   +   KKK+ ++  +  V I   D+++R   E+WYP     + +G  +                                 +   + + LP +RIK R+Q+ D+LPIN Y + L +LK++  ++   ++  + VK KED+  +L+ ++H QG+A  FL+D++  ++ +  ++ +  RGN++A+K++E +LKL GE+YL   LS  +N + Q + DCEVDP ++     S SS                    LQRQ++ +   V   W  I  S  +FP +L++ F + R+RL+Q+ R          ++ + ++S+ IFLRF+CPAIL+PSLF +  E P + +  R  TLVAK +Q+LANF+   G KE++M F+N F+E +   MQ FL+ IS+
Sbjct:  274 YSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFR---EVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYP--ILSDKAGDSL-------------------------GRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKT-----SGSSAGS-----------------LQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR---------QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRFQG-KENFMEFLNDFLEQEAARMQQFLEIIST 705

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0302834)

HSP 1 Score: 314.309 bits (804), Expect = 1.119e-86
Identity = 168/494 (34.01%), Postives = 279/494 (56.48%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISS 2801
            +SC S  ER  W+  L + + PN ++ RR + SL +W+ EAKN+P KKRYFCE+ LD+TL+ +T+ K  TDLLFWGE F+   + ++N +T+ +++   +   KKK+ ++  +  V I   D+++R   E+WYP     + +G  +                                 +   + + LP +RIK R+Q+ D+LPIN Y + L +LK++  ++   ++  + VK KED+  +L+ ++H QG+A  FL+D++  ++ +  ++ +  RGN++A+K++E +LKL GE+YL   LS  +N + Q + DCEVDP ++     S SS    Q                ++Q +L   V   W  I  S  +FP +L++ F + R+RL+Q+ R          ++ + ++S+ IFLRF+CPAIL+PSLF +  E P + +  R  TLVAK +Q+LANF+   G KE++M F+N F+E +   MQ FL+ IS+
Sbjct:  247 YSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFR---EVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILS--DKAGDSL-------------------------GRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKT-----SGSSAGSLQ----------------RQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR---------QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRFQG-KENFMEFLNDFLEQEAARMQQFLEIIST 678

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0340631)

HSP 1 Score: 313.923 bits (803), Expect = 1.257e-86
Identity = 168/494 (34.01%), Postives = 279/494 (56.48%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISS 2801
            +SC S  ER  W+  L + + PN ++ RR + SL +W+ EAKN+P KKRYFCE+ LD+TL+ +T+ K  TDLLFWGE F+   + ++N +T+ +++   +   KKK+ ++  +  V I   D+++R   E+WYP     + +G  +                                 +   + + LP +RIK R+Q+ D+LPIN Y + L +LK++  ++   ++  + VK KED+  +L+ ++H QG+A  FL+D++  ++ +  ++ +  RGN++A+K++E +LKL GE+YL   LS  +N + Q + DCEVDP ++     S SS    Q                ++Q +L   V   W  I  S  +FP +L++ F + R+RL+Q+ R          ++ + ++S+ IFLRF+CPAIL+PSLF +  E P + +  R  TLVAK +Q+LANF+   G KE++M F+N F+E +   MQ FL+ IS+
Sbjct:  247 YSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFR---EVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILS--DKAGDSL-------------------------GRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKT-----SGSSAGSLQ----------------RQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR---------QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRFQG-KENFMEFLNDFLEQEAARMQQFLEIIST 678

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Fly
Match: raskol (gene:FBgn0261570 transcript:FBtr0302835)

HSP 1 Score: 314.309 bits (804), Expect = 1.270e-86
Identity = 168/494 (34.01%), Postives = 279/494 (56.48%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISS 2801
            +SC S  ER  W+  L + + PN ++ RR + SL +W+ EAKN+P KKRYFCE+ LD+TL+ +T+ K  TDLLFWGE F+   + ++N +T+ +++   +   KKK+ ++  +  V I   D+++R   E+WYP     + +G  +                                 +   + + LP +RIK R+Q+ D+LPIN Y + L +LK++  ++   ++  + VK KED+  +L+ ++H QG+A  FL+D++  ++ +  ++ +  RGN++A+K++E +LKL GE+YL   LS  +N + Q + DCEVDP ++     S SS    Q                ++Q +L   V   W  I  S  +FP +L++ F + R+RL+Q+ R          ++ + ++S+ IFLRF+CPAIL+PSLF +  E P + +  R  TLVAK +Q+LANF+   G KE++M F+N F+E +   MQ FL+ IS+
Sbjct:  271 YSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFR---EVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILS--DKAGDSL-------------------------GRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKT-----SGSSAGSLQ----------------RQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGR---------QDMADNLISASIFLRFLCPAILSPSLFNITSELP-SARATRNLTLVAKTLQTLANFTRFQG-KENFMEFLNDFLEQEAARMQQFLEIIST 702

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Zebrafish
Match: dab2ipa (DAB2 interacting protein a [Source:ZFIN;Acc:ZDB-GENE-081104-516])

HSP 1 Score: 331.257 bits (848), Expect = 1.005e-93
Identity = 195/494 (39.47%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L  WI EAK++P KK+YFCE+ LD+TL+A+TT K  TD +FWGE F   +L  V ++T+ L+K   +   KKKK +++ +  VNI    ++ R  VE+WY  S    + G                                             PM+R+K+RYQ++ +LP+  Y    E++  + + +   ++  L VKNKE++A +L+++L   G A +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L+E QS                   +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L+ EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  126 FSCRSAAERDKWMENLRRAVHPNKDNTRRVENMLKCWIIEAKDLPAKKKYFCELCLDDTLYARTTCKLKTDNVFWGEHFEFNNLPSVKSITVHLYK---ETDKKKKKDKNNYVGLVNIPIATVTGRQFVEKWYSVSTPNPNKG-----------------------------------------KSPGPMVRMKSRYQSMSILPMELYKEFAEYITNNYMLMCSVLEPALSVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSSDLHEHQS-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFSLMQEYPDD-RTARTLTLIAKVTQNLANFTKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 540

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Zebrafish
Match: dab2ipa (DAB2 interacting protein a [Source:ZFIN;Acc:ZDB-GENE-081104-516])

HSP 1 Score: 331.257 bits (848), Expect = 1.154e-93
Identity = 195/494 (39.47%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L  WI EAK++P KK+YFCE+ LD+TL+A+TT K  TD +FWGE F   +L  V ++T+ L+K   +   KKKK +++ +  VNI    ++ R  VE+WY  S    + G                                             PM+R+K+RYQ++ +LP+  Y    E++  + + +   ++  L VKNKE++A +L+++L   G A +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L+E QS                   +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L+ EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  138 FSCRSAAERDKWMENLRRAVHPNKDNTRRVENMLKCWIIEAKDLPAKKKYFCELCLDDTLYARTTCKLKTDNVFWGEHFEFNNLPSVKSITVHLYK---ETDKKKKKDKNNYVGLVNIPIATVTGRQFVEKWYSVSTPNPNKG-----------------------------------------KSPGPMVRMKSRYQSMSILPMELYKEFAEYITNNYMLMCSVLEPALSVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSSDLHEHQS-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFSLMQEYPDD-RTARTLTLIAKVTQNLANFTKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 552

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Zebrafish
Match: dab2ipb (DAB2 interacting protein b [Source:ZFIN;Acc:ZDB-GENE-030131-2449])

HSP 1 Score: 325.479 bits (833), Expect = 5.833e-92
Identity = 193/494 (39.07%), Postives = 284/494 (57.49%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R + PN  N RR E  L LWI EAK++P KK+YFCE+ LD++L+A+TT K  TD +FWGE F   +L  V ++T+ +++   D+  KKKK +++ +  V+I    +++R  VE+WYP S                                     N  +  A+       PM+RIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L E QS                   +L M  ++ + KI+ S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E ++T MQ FL EIS
Sbjct:  110 FSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYR---DSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVS-----------------------------------QPNPGKGKAAG------PMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSSDLPEHQS-------------------NLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEQEWTNMQRFLLEIS 524

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Zebrafish
Match: dab2ipb (DAB2 interacting protein b [Source:ZFIN;Acc:ZDB-GENE-030131-2449])

HSP 1 Score: 325.865 bits (834), Expect = 8.953e-92
Identity = 193/494 (39.07%), Postives = 284/494 (57.49%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R + PN  N RR E  L LWI EAK++P KK+YFCE+ LD++L+A+TT K  TD +FWGE F   +L  V ++T+ +++   D+  KKKK +++ +  V+I    +++R  VE+WYP S                                     N  +  A+       PM+RIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L E QS                   +L M  ++ + KI+ S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E ++T MQ FL EIS
Sbjct:  153 FSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYR---DSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVS-----------------------------------QPNPGKGKAAG------PMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSSDLPEHQS-------------------NLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEQEWTNMQRFLLEIS 567

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Zebrafish
Match: dab2ipb (DAB2 interacting protein b [Source:ZFIN;Acc:ZDB-GENE-030131-2449])

HSP 1 Score: 325.479 bits (833), Expect = 1.499e-91
Identity = 193/494 (39.07%), Postives = 284/494 (57.49%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R + PN  N RR E  L LWI EAK++P KK+YFCE+ LD++L+A+TT K  TD +FWGE F   +L  V ++T+ +++   D+  KKKK +++ +  V+I    +++R  VE+WYP S                                     N  +  A+       PM+RIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L E QS                   +L M  ++ + KI+ S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E ++T MQ FL EIS
Sbjct:  181 FSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYR---DSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVS-----------------------------------QPNPGKGKAAG------PMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSSDLPEHQS-------------------NLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEQEWTNMQRFLLEIS 595

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Xenopus
Match: DAB2IP (DAB2 interacting protein [Source:NCBI gene;Acc:100145038])

HSP 1 Score: 329.717 bits (844), Expect = 1.216e-93
Identity = 198/494 (40.08%), Postives = 280/494 (56.68%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LWI EAK++P KK+Y CE+YLD+ L+A+TT K  TD +FWGE F   +L  + ++T+ L+K   +   KKKK +++ +  V+I    ++ R  VE+WYP      S G                                             PMIRIK RYQ+I +LP+  Y    E++  + + L   ++  L VKNKE++A +L+++L   G A +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  +KC   S S L E QS                   +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   58 FSCRSAAERDKWMENLRRAVHPNKDNSRRIENMLKLWIIEAKDLPAKKKYLCELYLDDILYARTTCKLKTDNVFWGEHFEFNNLPTLKSITVHLYK---ETDKKKKKDKNNYVGLVSIPIGAVTGRLFVEKWYPIVTPNPSKGKSCG-----------------------------------------PMIRIKTRYQSISILPMEMYKEFAEYITNNYMVLCSTLEGILSVKNKEEMASALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--NKC---STSDLPEHQS-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECNSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 472

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Xenopus
Match: DAB2IP (DAB2 interacting protein [Source:NCBI gene;Acc:100145038])

HSP 1 Score: 329.717 bits (844), Expect = 1.618e-93
Identity = 198/494 (40.08%), Postives = 280/494 (56.68%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LWI EAK++P KK+Y CE+YLD+ L+A+TT K  TD +FWGE F   +L  + ++T+ L+K   +   KKKK +++ +  V+I    ++ R  VE+WYP      S G                                             PMIRIK RYQ+I +LP+  Y    E++  + + L   ++  L VKNKE++A +L+++L   G A +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  +KC   S S L E QS                   +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   79 FSCRSAAERDKWMENLRRAVHPNKDNSRRIENMLKLWIIEAKDLPAKKKYLCELYLDDILYARTTCKLKTDNVFWGEHFEFNNLPTLKSITVHLYK---ETDKKKKKDKNNYVGLVSIPIGAVTGRLFVEKWYPIVTPNPSKGKSCG-----------------------------------------PMIRIKTRYQSISILPMEMYKEFAEYITNNYMVLCSTLEGILSVKNKEEMASALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--NKC---STSDLPEHQS-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECNSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 493

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Xenopus
Match: DAB2IP (DAB2 interacting protein [Source:NCBI gene;Acc:100145038])

HSP 1 Score: 329.717 bits (844), Expect = 1.975e-93
Identity = 198/494 (40.08%), Postives = 280/494 (56.68%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LWI EAK++P KK+Y CE+YLD+ L+A+TT K  TD +FWGE F   +L  + ++T+ L+K   +   KKKK +++ +  V+I    ++ R  VE+WYP      S G                                             PMIRIK RYQ+I +LP+  Y    E++  + + L   ++  L VKNKE++A +L+++L   G A +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  +KC   S S L E QS                   +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   72 FSCRSAAERDKWMENLRRAVHPNKDNSRRIENMLKLWIIEAKDLPAKKKYLCELYLDDILYARTTCKLKTDNVFWGEHFEFNNLPTLKSITVHLYK---ETDKKKKKDKNNYVGLVSIPIGAVTGRLFVEKWYPIVTPNPSKGKSCG-----------------------------------------PMIRIKTRYQSISILPMEMYKEFAEYITNNYMVLCSTLEGILSVKNKEEMASALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--NKC---STSDLPEHQS-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECNSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 486

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Xenopus
Match: DAB2IP (DAB2 interacting protein [Source:NCBI gene;Acc:100145038])

HSP 1 Score: 329.331 bits (843), Expect = 2.022e-93
Identity = 198/494 (40.08%), Postives = 280/494 (56.68%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LWI EAK++P KK+Y CE+YLD+ L+A+TT K  TD +FWGE F   +L  + ++T+ L+K   +   KKKK +++ +  V+I    ++ R  VE+WYP      S G                                             PMIRIK RYQ+I +LP+  Y    E++  + + L   ++  L VKNKE++A +L+++L   G A +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  +KC   S S L E QS                   +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   58 FSCRSAAERDKWMENLRRAVHPNKDNSRRIENMLKLWIIEAKDLPAKKKYLCELYLDDILYARTTCKLKTDNVFWGEHFEFNNLPTLKSITVHLYK---ETDKKKKKDKNNYVGLVSIPIGAVTGRLFVEKWYPIVTPNPSKGKSCG-----------------------------------------PMIRIKTRYQSISILPMEMYKEFAEYITNNYMVLCSTLEGILSVKNKEEMASALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--NKC---STSDLPEHQS-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECNSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 472

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Xenopus
Match: DAB2IP (DAB2 interacting protein [Source:NCBI gene;Acc:100145038])

HSP 1 Score: 329.717 bits (844), Expect = 2.228e-93
Identity = 198/494 (40.08%), Postives = 280/494 (56.68%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LWI EAK++P KK+Y CE+YLD+ L+A+TT K  TD +FWGE F   +L  + ++T+ L+K   +   KKKK +++ +  V+I    ++ R  VE+WYP      S G                                             PMIRIK RYQ+I +LP+  Y    E++  + + L   ++  L VKNKE++A +L+++L   G A +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  +KC   S S L E QS                   +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   75 FSCRSAAERDKWMENLRRAVHPNKDNSRRIENMLKLWIIEAKDLPAKKKYLCELYLDDILYARTTCKLKTDNVFWGEHFEFNNLPTLKSITVHLYK---ETDKKKKKDKNNYVGLVSIPIGAVTGRLFVEKWYPIVTPNPSKGKSCG-----------------------------------------PMIRIKTRYQSISILPMEMYKEFAEYITNNYMVLCSTLEGILSVKNKEEMASALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--NKC---STSDLPEHQS-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECNSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 489

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851])

HSP 1 Score: 332.798 bits (852), Expect = 1.585e-94
Identity = 193/494 (39.07%), Postives = 276/494 (55.87%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT+K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ + +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S++ L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   76 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 490

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851])

HSP 1 Score: 332.028 bits (850), Expect = 2.227e-94
Identity = 193/494 (39.07%), Postives = 276/494 (55.87%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT+K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ + +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S++ L E                    Q +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:   58 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSADLPE-------------------HQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 472

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851])

HSP 1 Score: 333.183 bits (853), Expect = 2.426e-94
Identity = 193/494 (39.07%), Postives = 276/494 (55.87%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT+K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ + +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S++ L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  182 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851])

HSP 1 Score: 333.183 bits (853), Expect = 2.612e-94
Identity = 193/494 (39.07%), Postives = 276/494 (55.87%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT+K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ + +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S++ L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  154 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 568

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Mouse
Match: Dab2ip (disabled 2 interacting protein [Source:MGI Symbol;Acc:MGI:1916851])

HSP 1 Score: 332.798 bits (852), Expect = 3.622e-94
Identity = 193/494 (39.07%), Postives = 276/494 (55.87%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT+K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ + +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S++ L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  125 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 539

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. UniProt/SwissProt
Match: sp|Q8MLZ5|GAP2_CAEEL (Ras GTPase-activating protein gap-2 OS=Caenorhabditis elegans OX=6239 GN=gap-2 PE=2 SV=2)

HSP 1 Score: 340.887 bits (873), Expect = 1.219e-95
Identity = 201/521 (38.58%), Postives = 305/521 (58.54%), Query Frame = 3

Query: 1305 LLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKE 2867
            L +  +SC +  ER KW+  L + + P    +RR E S+ +WI EAK +P K++Y+CE+ LD+TL+AKT++K  TD +FWGE F    L +++ V + L++ S    +KKKK    LI  V I    +S+R+ VERWY  + S++ SGT                            + ++ +    S+S   P +RIKAR+Q++ +LP+  Y +LLE L  + + L  +++  L V++KEDLA SL+ V++K  +A EFL DL+ +E++K DN++++ RGNT+A+KA+E ++KL+ + YL   LSDF+  + Q ++ CEVDPQ  K    SNSSL + ++L                   LM  V++ W KIL++    P+ L+ VF +LR RLE  +R A         L + ++SS IFLRF+CPAIL+PSLF L+ EYP +P   R  TL+AK +Q+LANFS   G KE +M FMN F++ ++  M+ FL  ISS +    S  + N  + VDA KE
Sbjct:  358 LASTYYSCRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESD---SKKKKDT--LIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGT----------------------------SRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQ--KLGNVSNSSLEKNRAL-------------------LMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREA---------LADTLISSSIFLRFLCPAILSPSLFNLVSEYP-SPTNARNLTLIAKTLQNLANFSKF-GGKEPHMEFMNEFVDREWHRMKDFLLRISSESK---SGPEKNADAIVDAGKE 810

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. UniProt/SwissProt
Match: sp|Q3UHC7|DAB2P_MOUSE (Disabled homolog 2-interacting protein OS=Mus musculus OX=10090 GN=Dab2ip PE=1 SV=1)

HSP 1 Score: 333.183 bits (853), Expect = 3.697e-93
Identity = 193/494 (39.07%), Postives = 276/494 (55.87%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT+K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ + +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S++ L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  182 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SSADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. UniProt/SwissProt
Match: sp|Q5VWQ8|DAB2P_HUMAN (Disabled homolog 2-interacting protein OS=Homo sapiens OX=9606 GN=DAB2IP PE=1 SV=2)

HSP 1 Score: 332.798 bits (852), Expect = 4.930e-93
Identity = 194/494 (39.27%), Postives = 274/494 (55.47%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT K  TD +FWGE F   +L  + TVT+ L++   +   KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ I +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S + L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:  182 FSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYR---ETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SAADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 596

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. UniProt/SwissProt
Match: sp|Q6P730|DAB2P_RAT (Disabled homolog 2-interacting protein OS=Rattus norvegicus OX=10116 GN=Dab2ip PE=1 SV=1)

HSP 1 Score: 313.538 bits (802), Expect = 8.736e-88
Identity = 186/479 (38.83%), Postives = 264/479 (55.11%), Query Frame = 3

Query: 1365 LTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            L R V PN  N RR E  L LW+ EAK++P KK+Y CE+ LD+ L+A+TT K  TD +FWGE F   +L  + TVT+ L++ +     KKKK ++  +  V++    ++ R  VE+WYP   + N  G                                             PMIRIKARYQ I +LP+  Y    E +  H + L   ++  L  K KE++A +L+++L   G   +FL+DL+  E+ +  DNE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S + L E Q                    +L M  ++ + KI++S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF LL EYPD+ +  RT TL+AK  Q+LANF+   GSKE YM FMN F+E+++T MQ FL EIS
Sbjct:    4 LRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDK---KKKKERNSYLGLVSLPAASVAGRQFVEKWYPV-VTPNPKG----------------------------------------GKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC---SAADLPEHQG-------------------NLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDD-RTARTLTLIAKVTQNLANFAKF-GSKEEYMSFMNQFLEHEWTNMQRFLLEIS 403

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. UniProt/SwissProt
Match: sp|Q9UJF2|NGAP_HUMAN (Ras GTPase-activating protein nGAP OS=Homo sapiens OX=9606 GN=RASAL2 PE=1 SV=2)

HSP 1 Score: 313.153 bits (801), Expect = 1.002e-86
Identity = 188/494 (38.06%), Postives = 281/494 (56.88%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S SER KW+  L R V+PN  N RR E  L LWI EAK++  KK+YFCE+ LD+TL A+TT+KT  D +FWGE F    L  ++++T+ ++K     + K K +   L   VNI T  ++ R  VE+WYP S    + G                                   T         P IRIK+R+Q I +LP+ +Y    EF+  +   L   ++  + V+NKE+LA +L+++L   G A +FL+DL+  E+ +  +++ +I R NTIA+K+IE YLKL+G++YL   L +F+  + + DE+CEVDP  SKC   S+S                    L+  Q +L M  ++ + KI++S   FPRELK VF S +++          ++  + ++ ER++S+ +FLRF+CPAI++PSLF L+ EYPD+ +  RT TL+AK IQ+LANF+   G+KE YM FMN F+E+++  M+ FL EIS
Sbjct:  138 FSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKDKNNYVGL---VNIPTASVTGRQFVEKWYPVSTPTPNKG----------------------------------KTGG-------PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDP--SKC---SSSE-------------------LIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC---------LNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDD-RTSRTLTLIAKVIQNLANFAKF-GNKEEYMAFMNDFLEHEWGGMKRFLLEIS 552

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. TrEMBL
Match: V4ANY2 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_114108 PE=4 SV=1)

HSP 1 Score: 360.533 bits (924), Expect = 7.230e-101
Identity = 206/544 (37.87%), Postives = 302/544 (55.51%), Query Frame = 3

Query: 1170 LLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISS 2801
            L  P    S+  +   IG K L       +SS L      +   H  +   SC +  ER KWL  L +  +PN ++ RR + SL LW+ EAKNV  KKRYFCEIYLD+TL+A+T+ K  +D+LFWGE F   +L  V+ +T+ L++ +     KKKK ++ L+  +NI   +I  R  VE+WY A+     SGT                                   A   + + LP+IR+KARYQ + +LPIN YS  +++LK    +L   ++  + V++KED+AI+LIN++ K G+A  FLSD++  EI + DNE++  RGN++A+KA+E Y+KL+GEKYL   + D+V  + +  +DCEVDP +          +N   +LQ               Q++L M   M WAKI++S  YFP EL+ VF S R R          +   + ++ + ++S  IFLRF+CPAIL+PSLF L  EYP   K  R  TL+AK IQ+LANF+   G KE YM F+N+F+E +  +M +FL +IS+
Sbjct:   12 LTTPASMNSMDMSSPDIGIKPL-------HSSVLGQDHCFQVSTHHGSKFISCRTAEERDKWLDSLRKTAKPNQEHCRRTDNSLKLWVVEAKNVTPKKRYFCEIYLDKTLYARTSIKMKSDMLFWGEHFEFNNLPPVDVITVNLFREAD---RKKKKDKNTLLGYINIPISEIGNRQYVEKWYTAA-----SGT--------------------------------VGKAGKDSKNDLPIIRLKARYQTVHILPINLYSEFIQYLKSDYCKLCESIEPLVNVRDKEDIAITLINIMQKLGMAQTFLSDVVMAEIGRLDNEHLTFRGNSMATKAMEAYMKLVGEKYLHDTIGDYVRNLIECQDDCEVDPTK----------VNNVTTLQC-------------HQKNLEMYCQMAWAKIMNSYCYFPSELREVFSSFRDRC---------IKRGKEDMSDNLISGSIFLRFLCPAILSPSLFNLTQEYPQE-KAARNLTLIAKTIQTLANFTKFGGGKEEYMTFLNSFVERESNSMHNFLHQIST 475

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. TrEMBL
Match: A0A3Q1GA50 (Uncharacterized protein OS=Acanthochromis polyacanthus OX=80966 PE=4 SV=1)

HSP 1 Score: 346.665 bits (888), Expect = 5.092e-99
Identity = 193/494 (39.07%), Postives = 281/494 (56.88%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKS-DNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L +W+ EAK++P KKRYFCE+ LD++L+A+T+ K  TD +FWGE F+   L  V++VT+ L+K   D   K+KK +   +  VNI    ++ R  VE+WY  S    S G   V                                         P +R+KARYQ+I +LP+ +Y    E++  + + L   ++A + ++ KE+LA +L+++LH  G A +FL+DL+  E+ +  DN+ +I R NT+A+K+IE YLKLIG+KYL   L +F+  + + DE+CEVDP R             C +             LL+ Q +L M  ++ + KIL S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPA+++PSLF L+ EYPD  +  RT TL+AK IQ+LANFS   G+KE YMLFMN F+E ++++MQ FL+EIS
Sbjct:   82 FSCRSAAERDKWMENLRRAVHPNKDNSRRLENVLTVWVIEAKDLPAKKRYFCELCLDDSLYARTSCKLRTDNVFWGERFDFSSLPSVSSVTLHLYK---DTDRKRKKDKSSYVGLVNIPVATVTGRQLVEKWYSVSTPSTSRGKSSV-----------------------------------------PTVRVKARYQSIVILPMEQYKEFAEYISSNYLLLCSTLEASISLRAKEELAAALVHILHSTGKAKDFLTDLMMSEVDRCRDNDQLIFRENTLATKSIEEYLKLIGQKYLQDALGEFIKALYESDENCEVDPSR-------------CSTSD-----------LLEHQANLRMCCELAFCKILDSYRVFPRELKEVFASWRQECGNRGR---------PDISERLISASLFLRFLCPAVMSPSLFDLMQEYPDE-RTARTLTLIAKVIQNLANFSKF-GTKEEYMLFMNDFVERQWSSMQRFLQEIS 496

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. TrEMBL
Match: A0A3Q1ER52 (Uncharacterized protein OS=Acanthochromis polyacanthus OX=80966 PE=4 SV=1)

HSP 1 Score: 341.658 bits (875), Expect = 5.931e-98
Identity = 194/494 (39.27%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L +W+ EAK++P KKRYFCE+ LD++L+A+T+ K  TD +FWGE F+   L  V++VT+ L+K   D   K+KK +   +  VNI    ++ R  VE+WY                                          S ST S   S  +P +R+KARYQ+I +LP+ +Y    E++  + + L   ++A + ++ KE+LA +L+++LH  G A +FL+DL+  E+ +  DN+ +I R NT+A+K+IE YLKLIG+KYL   L +F+  + + DE+CEVDP R             C +             LL+ Q +L M  ++ + KIL S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPA+++PSLF L+ EYPD  +  RT TL+AK IQ+LANFS   G+KE YMLFMN F+E ++++MQ FL+EIS
Sbjct:   85 FSCRSAAERDKWMENLRRAVHPNKDNSRRLENVLTVWVIEAKDLPAKKRYFCELCLDDSLYARTSCKLRTDNVFWGERFDFSSLPSVSSVTLHLYK---DTDRKRKKDKSSYVGLVNIPVATVTGRQLVEKWY------------------------------------------SVSTPSTRKS-SVPTVRVKARYQSIVILPMEQYKEFAEYISSNYLLLCSTLEASISLRAKEELAAALVHILHSTGKAKDFLTDLMMSEVDRCRDNDQLIFRENTLATKSIEEYLKLIGQKYLQDALGEFIKALYESDENCEVDPSR-------------CSTSD-----------LLEHQANLRMCCELAFCKILDSYRVFPRELKEVFASWRQECGNRGR---------PDISERLISASLFLRFLCPAVMSPSLFDLMQEYPDE-RTARTLTLIAKVIQNLANFSKF-GTKEEYMLFMNDFVERQWSSMQRFLQEIS 497

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. TrEMBL
Match: A0A3S2UDU6 (Uncharacterized protein OS=Oryzias javanicus OX=123683 GN=OJAV_G00094940 PE=4 SV=1)

HSP 1 Score: 351.673 bits (901), Expect = 6.827e-98
Identity = 192/494 (38.87%), Postives = 285/494 (57.69%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L +W+ EAK++P KKRYFCE+ LD++L+A+T+ K  TD +FWGE F+ C L  +N++T+ L+K   D   K+KK +   +  VNI    ++ R  VE+WY  S                                         + +++     +P +R+KARYQ+I +LP+ +Y    E++  + + L   ++A + ++ KE+LA +L+++LH  G A +FL+DL+  E+ +  DN+ +I R NT+A+K+IE YLKLIG+KYL   L +F+  + + DE+CEVDP  S+C   S S L E                    Q +L M  ++ + KIL S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPA+++PSLF L+ EYPD  +  RT TL+AK IQ+LANFS   G+KE YMLFMN F+E ++++MQ FL+EIS
Sbjct:   56 FSCRSAAERDKWMENLRRAVHPNKDNSRRLENVLTVWVIEAKDLPAKKRYFCELCLDDSLYARTSCKLKTDNIFWGEHFDFCSLPSINSITLHLYK---DTDRKRKKDKSSYVGLVNIPVSTVTGRQLVEKWYSVS-----------------------------------------TPSTIRGKSSIPTVRVKARYQSIVILPMEQYKEFAEYISSNYLLLCSTLEASISLRAKEELAAALVHILHSTGKAKDFLTDLMMSEVDRCRDNDQLIFRENTLATKSIEEYLKLIGQKYLQDALGEFIKALYESDENCEVDP--SRC---STSDLAE-------------------HQANLRMCCELAFCKILDSYRVFPRELKEVFASWRQECSNRGRP---------DISERLISASLFLRFLCPAVMSPSLFDLMQEYPDE-RTARTLTLIAKVIQNLANFSKF-GTKEEYMLFMNDFVERQWSSMQRFLQEIS 470

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. TrEMBL
Match: A0A3B3DB07 (Uncharacterized protein OS=Oryzias melastigma OX=30732 PE=4 SV=1)

HSP 1 Score: 350.903 bits (899), Expect = 1.331e-97
Identity = 192/494 (38.87%), Postives = 285/494 (57.69%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L +W+ EAK++P KKRYFCE+ LD++L+A+T+ K  TD +FWGE F+ C L  +N++T+ L+K   D   K+KK +   +  VNI    ++ R  VE+WY  S                                         + +++     +P +R+KARYQ+I +LP+ +Y    E++  + + L   ++A + ++ KE+LA +L+++LH  G A +FL+DL+  E+ +  DN+ +I R NT+A+K+IE YLKLIG+KYL   L +F+  + + DE+CEVDP  S+C   S S L E                    Q +L M  ++ + KIL S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPA+++PSLF L+ EYPD  +  RT TL+AK IQ+LANFS   G+KE YMLFMN F+E ++++MQ FL+EIS
Sbjct:   56 FSCRSAAERDKWMENLRRAVHPNKDNSRRLENVLTVWVIEAKDLPAKKRYFCELCLDDSLYARTSCKLKTDNIFWGEHFDFCSLPSINSITLHLYK---DTDRKRKKDKSSYVGLVNIPVSTVTGRQLVEKWYSVS-----------------------------------------TPSTIRGKSSIPTVRVKARYQSIIILPMEQYKEFAEYISSNYLLLCSTLEASISLRAKEELAAALVHILHSTGKAKDFLTDLMMSEVDRCRDNDQLIFRENTLATKSIEEYLKLIGQKYLQDALGEFIKALYESDENCEVDP--SRC---STSDLAE-------------------HQANLRMCCELAFCKILDSYRVFPRELKEVFASWRQECSNRGRP---------DISERLISASLFLRFLCPAVMSPSLFDLMQEYPDE-RTARTLTLIAKVIQNLANFSKF-GTKEEYMLFMNDFVERQWSSMQRFLQEIS 470

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Cavefish
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:103023248])

HSP 1 Score: 333.954 bits (855), Expect = 6.773e-95
Identity = 195/494 (39.47%), Postives = 284/494 (57.49%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+YFCE+ LD++L+A+TT K   D +FWGE F   +L  V  +T+ L++   D+  KKKK +++ +  V+I  + +++R  VE+WYP S    S G                                   TA        PMIRIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC      S N+                L + Q +L M  ++ + KI+SS   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E+++T MQ FL EIS
Sbjct:  151 FSCRSSAERDKWMENLRRAVHPNKDNSRRVENMLRLWVIEAKDLPAKKKYFCELCLDDSLYARTTCKLKADNIFWGEHFEFSNLPAVQNITVHLYR---DSEKKKKKDKNNYVGLVSIPVETVTSRQLVEKWYPVSTPNPSKG----------------------------------KTAG-------PMIRIKARYQSMNILPMEMYKEFAEYTTNNYMLLCSVLEPAISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC------SPND----------------LPEHQSNLKMCCELAFCKIISSYCVFPRELKEVFASWRQECGNRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEHEWTNMQRFLLEIS 565

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Cavefish
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:103023248])

HSP 1 Score: 333.954 bits (855), Expect = 1.188e-94
Identity = 195/494 (39.47%), Postives = 284/494 (57.49%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+YFCE+ LD++L+A+TT K   D +FWGE F   +L  V  +T+ L++   D+  KKKK +++ +  V+I  + +++R  VE+WYP S    S G                                   TA        PMIRIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC      S N+                L + Q +L M  ++ + KI+SS   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E+++T MQ FL EIS
Sbjct:  151 FSCRSSAERDKWMENLRRAVHPNKDNSRRVENMLRLWVIEAKDLPAKKKYFCELCLDDSLYARTTCKLKADNIFWGEHFEFSNLPAVQNITVHLYR---DSEKKKKKDKNNYVGLVSIPVETVTSRQLVEKWYPVSTPNPSKG----------------------------------KTAG-------PMIRIKARYQSMNILPMEMYKEFAEYTTNNYMLLCSVLEPAISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC------SPND----------------LPEHQSNLKMCCELAFCKIISSYCVFPRELKEVFASWRQECGNRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEHEWTNMQRFLLEIS 565

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Cavefish
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:103023248])

HSP 1 Score: 333.954 bits (855), Expect = 2.210e-94
Identity = 195/494 (39.47%), Postives = 284/494 (57.49%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+YFCE+ LD++L+A+TT K   D +FWGE F   +L  V  +T+ L++   D+  KKKK +++ +  V+I  + +++R  VE+WYP S    S G                                   TA        PMIRIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC      S N+                L + Q +L M  ++ + KI+SS   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E+++T MQ FL EIS
Sbjct:  179 FSCRSSAERDKWMENLRRAVHPNKDNSRRVENMLRLWVIEAKDLPAKKKYFCELCLDDSLYARTTCKLKADNIFWGEHFEFSNLPAVQNITVHLYR---DSEKKKKKDKNNYVGLVSIPVETVTSRQLVEKWYPVSTPNPSKG----------------------------------KTAG-------PMIRIKARYQSMNILPMEMYKEFAEYTTNNYMLLCSVLEPAISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC------SPND----------------LPEHQSNLKMCCELAFCKIISSYCVFPRELKEVFASWRQECGNRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEHEWTNMQRFLLEIS 593

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Cavefish
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:103023248])

HSP 1 Score: 333.569 bits (854), Expect = 1.535e-93
Identity = 195/494 (39.47%), Postives = 284/494 (57.49%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+YFCE+ LD++L+A+TT K   D +FWGE F   +L  V  +T+ L++   D+  KKKK +++ +  V+I  + +++R  VE+WYP S    S G                                   TA        PMIRIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC      S N+                L + Q +L M  ++ + KI+SS   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E+++T MQ FL EIS
Sbjct:  344 FSCRSSAERDKWMENLRRAVHPNKDNSRRVENMLRLWVIEAKDLPAKKKYFCELCLDDSLYARTTCKLKADNIFWGEHFEFSNLPAVQNITVHLYR---DSEKKKKKDKNNYVGLVSIPVETVTSRQLVEKWYPVSTPNPSKG----------------------------------KTAG-------PMIRIKARYQSMNILPMEMYKEFAEYTTNNYMLLCSVLEPAISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC------SPND----------------LPEHQSNLKMCCELAFCKIISSYCVFPRELKEVFASWRQECGNRGR---------PDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEHEWTNMQRFLLEIS 758

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Cavefish
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:103023248])

HSP 1 Score: 327.02 bits (837), Expect = 1.198e-92
Identity = 194/494 (39.27%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L LW+ EAK++P KK+YFCE+ LD++L+A+TT K   D +FWGE F   +L  V  +T+ L++   D+  KKKK +++ +  V+I  + +++R  VE+WYP S    S G                                   TA        PMIRIKARYQ++++LP+  Y    E+   + + L   ++  + VKNKE++A +L+++L   G   +FL+DL+  E+ +  +NE++I R NT+ +KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC      S N+                L + Q +L M  ++ + KI+SS   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF+   G+KE YM FMN F+E+++T MQ FL EIS
Sbjct:   83 FSCRSSAERDKWMENLRRAVHPNKDNSRRVENMLRLWVIEAKDLPAKKKYFCELCLDDSLYARTTCKLKADNIFWGEHFEFSNLPAVQNITVHLYR---DSEKKKKKDKNNYVGLVSIPVETVTSRQLVEKWYPVSTPNPSKG----------------------------------KTAG-------PMIRIKARYQSMNILPMEMYKEFAEYTTNNYMLLCSVLEPAISVKNKEEMACALVHILQSTG--KDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDP--SKC------SPND----------------LPEHQSNLKMCCELAFCKIISSYCVFPRELKEVFASWRQECGNRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTKF-GNKEEYMSFMNQFLEHEWTNMQRFLLEIS 495

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000945.1 (pep scaffold:Pmarinus_7.0:GL477254:323984:383899:1 gene:ENSPMAG00000000852.1 transcript:ENSPMAT00000000945.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 291.967 bits (746), Expect = 1.779e-81
Identity = 182/491 (37.07%), Postives = 267/491 (54.38%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLIL-SDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFL 2786
            FSC S +E+ KW+  L R+V+PN  N +R E  L +WI EAK +P KK+YFCEI LD+TL+A+T +K   D LFWGE F   +L  V  + + L+K +   + K+K S   L+  +++E    S R  VE+WYP S      G   V                                         P +RIK R+Q + +LP+ +Y    EFL    + L   ++  L VK+KE+LA +L+  LH  G   EFL++L+  E+ + S+NE+++ R NT+A+KAIE YLK++G+ YL   L  +FV  +   DE+CEV+             L++C S +  D            + +L M  ++ + KILSS   FP EL+ VF S R+  E   R         + + ER++S+ +FLRF+CPAI++PSLFGL  EYPD  +  RT TL+AK +Q+LANF+   G+KE YM FMN F+E ++  M+ FL
Sbjct:   14 FSCRSAAEQDKWMENLRRIVQPNKDNIQRVENDLKVWIIEAKELPAKKKYFCEICLDDTLYARTASKAKVDNLFWGEHFEFSNLPAVKHIMVHLYKDTDKKKKKEKSSYVGLV-NISVEG-GTSGRQFVEKWYPLSTPNPGKGKGAV-----------------------------------------PTVRIKWRHQQLSILPMERYKEFAEFLSASCLPLCLLLEPVLGVKSKEELARALVRFLHTTGRVKEFLAELVIAEVTRCSENEHLLFRENTLATKAIEEYLKMVGQWYLHDALEGEFVRALYDSDENCEVE-------------LSKCSSAELADH-----------RNNLRMCCELAFCKILSSCCVFPAELRDVFSSWRRLCEARGR---------AEISERLISASLFLRFLCPAIMSPSLFGLSQEYPDE-RTARTLTLIAKVVQNLANFTKF-GNKEDYMTFMNGFLEQEWGRMKQFL 426

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Yeast
Match: BUD2 (GTPase activating factor for Rsr1p/Bud1p; plays a role in spindle position checkpoint distinct from its role in bud site selection; required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types; contains two PH-like domains [Source:SGD;Acc:S000001575])

HSP 1 Score: 87.4261 bits (215), Expect = 1.215e-17
Identity = 61/225 (27.11%), Postives = 111/225 (49.33%), Query Frame = 3

Query: 2130 NMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQ--MDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            N + RGN+I +K+IE Y   +G +YLS  LS  +  I + ++ CE+DP R K +       +E +             ++    + L   V  IW ++ ++S   P E+++V    R++LE   +D T   + N         +S  +FLRF CP IL P LF  + +   N    R  TL++K + +L+  +    +KE +++ MN FI+ +   +  ++ +++
Sbjct:  557 NSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEK-------DEVKK----------RKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNG--------ISGLLFLRFFCPVILNPKLFKYVSQNL-NETARRNLTLISKVLLNLSTLTQF-ANKEPWLMKMNNFIDKRHNDLLDYIDKMT 754

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Nematostella
Match: EDO35799 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKG2])

HSP 1 Score: 288.5 bits (737), Expect = 1.321e-80
Identity = 175/498 (35.14%), Postives = 267/498 (53.61%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPL--KKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK--SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISS 2801
            FSC S  E  KW++ + + ++P    + R +ISL++W+ EAK      KKRYFCE+ LD+ L+A+TT+KT  D LFWGE F+   L  ++T+T+ ++K   D  AK KK +  L+  VNI  +D+ +   VE+W+P   +                                          +  N+D    IR+K +YQ I +LP+  Y+ +L +L  + + L   +++ +  K K+++A  ++ VL   G A EFL D++  E+ +  S +EN++ RGN+ A+KA++ Y+K++GE   S  L DFV  +    EDCEVDP +S                 NG   S+        QE+L    +  W  IL SS  FP +L+  F   R+R            N   +L  +++S+ IFLRF+CPAI++PSLF L+ EYP N ++LRT TL+AK IQ+LANF+   G KE YM FMN F++N+F  M+ F+  ISS
Sbjct:   34 FSCRSAQELNKWVNSIKKSIQPARDQQNRMDISLSVWVCEAKGAMTTPKKRYFCELLLDKMLYARTTSKTKVDTLFWGENFSFDDLLDLSTITVNIYK---DLEAKNKKEKRKLVGTVNIPVRDLDSSQEVEKWFPVDMT------------------------------------------TKGNADS-GSIRLKIKYQKIHILPLTTYNEMLSYLSNNYMHLCGTLESAVSSKVKDEIAGVILRVLQPVGKAQEFLVDIVMDEVNRLGSADENLVFRGNSFATKAMDTYMKMVGE---SETLGDFVQSVYAMSEDCEVDPAKS----------------VNGSIQSN--------QENLKAFAEKAWNHILCSSCIFPCDLQDTFHEFRQR----------SINGSRDLSNKLISASIFLRFLCPAIMSPSLFHLVQEYP-NERILRTLTLIAKVIQNLANFTKF-GGKEDYMGFMNDFVQNEFDKMREFVATISS 446

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Nematostella
Match: EDO36190 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJB4])

HSP 1 Score: 116.701 bits (291), Expect = 1.932e-26
Identity = 121/471 (25.69%), Postives = 209/471 (44.37%), Query Frame = 3

Query: 1404 RQEISLNLWIQEAKNVPLKK--RYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHL-EQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQH---AVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            +Q  SL L + EA  +PL K    +C + L+E    +T T      L W EEF    L   V++ T+ L+        K  +++  LI  V +    +     V+ WYP + +                                     S   A + N      +RI+ ++ +  ++P+ +Y  L E L      AV  L ++      K++  LA +L+ +   +      L  +  +EI+K D +  + RG ++A+  ++ Y+K++   YL   + D + +I +  + CE++P  +K E  +++ +N                 L Q  E L   +D I+    +S+   P+ L+ +F  L++ ++  D+ A   DN    +  R+VS  +FLR  CPAI+ P    L+ E P +    RT TLVAKC+Q LAN  +  G+KES M  +N F++     M SF+ E+S
Sbjct:  233 KQLRSLELNVIEAHKLPLNKVSHPYCMVSLNEVKTCRTKTFEGQTPL-WNEEFKFNDLPSDVSSFTLSLYN-------KSWRTKDVLIGHVLVPLNKLPKGQTVDDWYPLAAA-------------------------------------SHGKAEVGN------VRIRVKFTHEIIMPVEEYEALKEILLDEDLVAVTALGQV-----CKDRVVLASTLLKIFRHEKQEIFLLKTMNAREIEKQDEQATLFRGASLATSLMDQYMKMVAIPYLQHTIKDVILKILECKQSCELNP--AKMEKGADTVVN-----------------LKQLLEFLFEAIDAIF----TSAEECPKTLRYLFGCLQQNVK--DKWA---DN--QTVRTRVVSGFLFLRLFCPAIMNPKTCNLMSELP-SATAARTLTLVAKCLQKLANLVEF-GAKESCMTPVNPFMQKNRERMVSFMDELS 615

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Nematostella
Match: EDO43446 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYE3])

HSP 1 Score: 116.316 bits (290), Expect = 3.382e-26
Identity = 95/318 (29.87%), Postives = 153/318 (48.11%), Query Frame = 3

Query: 1890 IRIKARYQNIDVLPINKYSHLLE-FLKQHAVQLLHEMDAHLK---VKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANF--SDLTGS-KESYMLFMNTFI--ENKFTTMQSFLKEISSSTDDD 2816
            +R+K  Y    V P + Y  L E  L+    + +    A++    VK+K   A +L+ V        +F+  ++  E+  + + N + RGN++ +KAI+ ++K  G +YL   +   V+ I +  + CE+DP R                L++GD        L Q   +L   V+ + A I  S++  P  +  VFV++R+       +A Q  + + ++    VS  +FLRF  PAIL P LF +  E+PD P V RT TL +K IQSL N   S + G  KE YM  +   I  ++  T ++ FL  ISS+   D
Sbjct:  276 LRLKVCYTEDYVFPSSYYEPLREAILEIEGHKDVTTTPAYILSEIVKDKLTAARALVRVFTHHNKVVDFIKAVVDHEVNTTADCNTLFRGNSLGTKAIDEFMKHAGMQYLHETIKTLVDEIYEERKCCEIDPSR----------------LRDGDS-------LPQNLANLQGYVNKLCAAITCSAMACPTAMSKVFVTIRE-------SAVQRFSDEPDVRYTAVSGFVFLRFFAPAILNPKLFQMRNEHPD-PLVARTLTLASKAIQSLGNLVSSVICGQVKEPYMESLKAMILDQDHITAVKRFLDAISSTVCAD 562

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Nematostella
Match: EDO40933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5U4])

HSP 1 Score: 68.9366 bits (167), Expect = 1.424e-11
Identity = 69/245 (28.16%), Postives = 118/245 (48.16%), Query Frame = 3

Query: 2106 EIKKSDNENMILRGNTIASKAIEVYLKL-IGEKYLSLILSDFVNRI-SQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNG--DKSSHFHPML----LQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRK-RLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGS-KESYMLFMNTFIENKFTTMQSFLKEISSSTD 2810
            E  +S+N N +LR NT  S+ +  Y +   G++YL   L + +N + SQ D   E++P +   E + +       +L+    D    F   L    LQ   SL + +      I+SS    P  ++ +  ++++  +E+      +  N+       ++     LRFI PAI+TP+ + L+ + P    + R  TL+AK +QS+AN + ++   KE YM  +  F  N    MQSFL ++SS  D
Sbjct:  147 EFAESENFNSLLRANTAISRMMTTYTRRGPGQEYLKCTLEEPLNDLMSQEDLVLEINPIKVYIELYGHPMDESSLTLERAMDDPEVMFRTKLRIKKLQDISSLFLGI------IISSLSQVPYGIQWLCRAIKELAMEKFPEATPEQINA-------MIGGFFLLRFINPAIVTPTAYMLVNKQPTY-TMRRNLTLIAKILQSMANKNVVSSHFKEEYMQPLQPFAINHVDLMQSFLSDLSSVPD 377

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Medaka
Match: ENSORLT00000022035.2 (disabled homolog 2-interacting protein-like [Source:NCBI gene;Acc:101175325])

HSP 1 Score: 350.903 bits (899), Expect = 5.066e-101
Identity = 192/494 (38.87%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V PN  N RR E  L +W+ EAK++P KKRYFCE+ LD++L+A+T+ K  TD +FWGE F+ C L  VN++T+ L+K   D   K+KK +   +  VNI    ++ R  VE+WY  S                                         + +++     +P +R+KARYQ+I +LP+ +Y    E++  + + L   ++A + ++ KE+LA +L+++LH  G A +FL+DL+  E+ +  DN+ +I R NT+A+K+IE YLKLIG+KYL   L +F+  + + DE+CEVDP R      S S L E                    Q +L M  ++ + KIL S   FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPA+++PSLF L+ EYPD  +  RT TL+AK IQ+LANFS   G+KE YMLFMN F+E ++++MQ FL+EIS
Sbjct:   56 FSCRSAAERDKWMENLRRAVHPNKDNSRRLENVLTVWVIEAKDLPAKKRYFCELCLDDSLYARTSCKLKTDNIFWGEHFDFCSLPSVNSITLHLYK---DTDRKRKKDKSSYVGLVNIPVSTVTGRQLVEKWYSVS-----------------------------------------TPSTIRGKSSIPNVRVKARYQSIIILPMEQYKEFAEYISSNYLLLCSTLEASISLRAKEELAAALVHILHSTGKAKDFLTDLMMSEVDRCRDNDQLIFRENTLATKSIEEYLKLIGQKYLQDALGEFIKALYESDENCEVDPARC-----STSDLAE-------------------HQANLRMCCELAFCKILDSYRVFPRELKEVFASWRQECSNRGRP---------DISERLISASLFLRFLCPAVMSPSLFDLMQEYPDE-RTARTLTLIAKVIQNLANFSKF-GTKEEYMLFMNDFVERQWSSMQRFLQEIS 470

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BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Medaka
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:101160924])

HSP 1 Score: 329.717 bits (844), Expect = 2.462e-93
Identity = 196/494 (39.68%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V+PN  N RR E  L LWI EAK++P KK+YFCE+ LDE+L+A+TT K  TD +FWGE F   +L  V ++T  L+K +     KKKK +++ I  VNI    +S R  +E+WYP S      G                                             PMIRIKARYQ++ +LP+  Y    E++  + + L   ++  + VK+KE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L + QS                   +L M  ++ + KI+ S  +FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF++  G+KE YM FMN F+E++++ MQ FL EIS
Sbjct:  126 FSCRSAAERDKWMENLRRAVQPNKDNSRRVENILRLWIIEAKDLPAKKKYFCELCLDESLYARTTCKLKTDNVFWGEHFEFSNLPAVRSITAHLYKDTD---KKKKKDKNNYIGLVNISVAAVSGRQFMEKWYPVSTPNPPKG-----------------------------------------KTSGPMIRIKARYQSMSILPMEMYKEFAEYITNNYMLLCSVLEPAISVKSKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLATKAIEEYLKLVGQKYLQDTLGEFIKALYESDENCEVDP--SKC---SSSDLPDHQS-------------------NLKMCCELAFCKIIKSYCFFPRELKEVFASWRQECSSRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTNF-GNKEEYMSFMNQFLEHEWSDMQRFLLEIS 540

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Medaka
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:101160924])

HSP 1 Score: 328.561 bits (841), Expect = 3.482e-93
Identity = 196/494 (39.68%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V+PN  N RR E  L LWI EAK++P KK+YFCE+ LDE+L+A+TT K  TD +FWGE F   +L  V ++T  L+K +     KKKK +++ I  VNI    +S R  +E+WYP S      G                                             PMIRIKARYQ++ +LP+  Y    E++  + + L   ++  + VK+KE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L + QS                   +L M  ++ + KI+ S  +FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF++  G+KE YM FMN F+E++++ MQ FL EIS
Sbjct:   69 FSCRSAAERDKWMENLRRAVQPNKDNSRRVENILRLWIIEAKDLPAKKKYFCELCLDESLYARTTCKLKTDNVFWGEHFEFSNLPAVRSITAHLYKDTD---KKKKKDKNNYIGLVNISVAAVSGRQFMEKWYPVSTPNPPKG-----------------------------------------KTSGPMIRIKARYQSMSILPMEMYKEFAEYITNNYMLLCSVLEPAISVKSKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLATKAIEEYLKLVGQKYLQDTLGEFIKALYESDENCEVDP--SKC---SSSDLPDHQS-------------------NLKMCCELAFCKIIKSYCFFPRELKEVFASWRQECSSRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTNF-GNKEEYMSFMNQFLEHEWSDMQRFLLEIS 483

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Medaka
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:101160924])

HSP 1 Score: 328.946 bits (842), Expect = 3.610e-93
Identity = 196/494 (39.68%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V+PN  N RR E  L LWI EAK++P KK+YFCE+ LDE+L+A+TT K  TD +FWGE F   +L  V ++T  L+K +     KKKK +++ I  VNI    +S R  +E+WYP S      G                                             PMIRIKARYQ++ +LP+  Y    E++  + + L   ++  + VK+KE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L + QS                   +L M  ++ + KI+ S  +FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF++  G+KE YM FMN F+E++++ MQ FL EIS
Sbjct:  108 FSCRSAAERDKWMENLRRAVQPNKDNSRRVENILRLWIIEAKDLPAKKKYFCELCLDESLYARTTCKLKTDNVFWGEHFEFSNLPAVRSITAHLYKDTD---KKKKKDKNNYIGLVNISVAAVSGRQFMEKWYPVSTPNPPKG-----------------------------------------KTSGPMIRIKARYQSMSILPMEMYKEFAEYITNNYMLLCSVLEPAISVKSKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLATKAIEEYLKLVGQKYLQDTLGEFIKALYESDENCEVDP--SKC---SSSDLPDHQS-------------------NLKMCCELAFCKIIKSYCFFPRELKEVFASWRQECSSRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTNF-GNKEEYMSFMNQFLEHEWSDMQRFLLEIS 522

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Medaka
Match: dab2ipb (DAB2 interacting protein [Source:NCBI gene;Acc:101160924])

HSP 1 Score: 330.102 bits (845), Expect = 4.254e-93
Identity = 196/494 (39.68%), Postives = 283/494 (57.29%), Query Frame = 3

Query: 1320 FSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKK-SDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEIS 2798
            FSC S +ER KW+  L R V+PN  N RR E  L LWI EAK++P KK+YFCE+ LDE+L+A+TT K  TD +FWGE F   +L  V ++T  L+K +     KKKK +++ I  VNI    +S R  +E+WYP S      G                                             PMIRIKARYQ++ +LP+  Y    E++  + + L   ++  + VK+KE++A +L+++L   G A +FL+DL+  E+ +  +NE++I R NT+A+KAIE YLKL+G+KYL   L +F+  + + DE+CEVDP  SKC   S+S L + QS                   +L M  ++ + KI+ S  +FPRELK VF S R+      R          ++ ER++S+ +FLRF+CPAI++PSLF L  EYPD+ +  RT TL+AK  Q+LANF++  G+KE YM FMN F+E++++ MQ FL EIS
Sbjct:  151 FSCRSAAERDKWMENLRRAVQPNKDNSRRVENILRLWIIEAKDLPAKKKYFCELCLDESLYARTTCKLKTDNVFWGEHFEFSNLPAVRSITAHLYKDTD---KKKKKDKNNYIGLVNISVAAVSGRQFMEKWYPVSTPNPPKG-----------------------------------------KTSGPMIRIKARYQSMSILPMEMYKEFAEYITNNYMLLCSVLEPAISVKSKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLATKAIEEYLKLVGQKYLQDTLGEFIKALYESDENCEVDP--SKC---SSSDLPDHQS-------------------NLKMCCELAFCKIIKSYCFFPRELKEVFASWRQECSSRGRP---------DISERLISASLFLRFLCPAIMSPSLFNLTQEYPDD-RTARTLTLIAKVTQNLANFTNF-GNKEEYMSFMNQFLEHEWSDMQRFLLEIS 565

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1)

HSP 1 Score: 2222.59 bits (5758), Expect = 0.000e+0
Identity = 1134/1144 (99.13%), Postives = 1139/1144 (99.56%), Query Frame = 3

Query:  585 MKSQQRTYSKPSGFNLSKTASHDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENXXXXXXXXXXXXXXXXAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDVTEPVGVSYSHSYHDXXXXXXXXXXXXDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNYLMTQSMIQDHKNYSHIPHPDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERLHGISSDSSGYETLNRSNCKISNEDEINMYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 4016
            MKSQQRTYSKPSGFNLSKTASHDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSC SESERKKW+SVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQ HLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLL EMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPD+TEPVGVSYSHSYHD NGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGN+LMTQSMIQDHKNYSHIPH DSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIER+HGISSDSSGYETLNRSNCKISNEDEIN+YDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH
Sbjct:    1 MKSQQRTYSKPSGFNLSKTASHDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDITEPVGVSYSHSYHDTNGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNHLMTQSMIQDHKNYSHIPHSDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERVHGISSDSSGYETLNRSNCKISNEDEINIYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 1144

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1)

HSP 1 Score: 2178.29 bits (5643), Expect = 0.000e+0
Identity = 1115/1136 (98.15%), Postives = 1123/1136 (98.86%), Query Frame = 3

Query:  609 SKPSGFNLSKTASHDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENXXXXXXXXXXXXXXXXAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDVTEPVGVSYSHSYHDXXXXXXXXXXXXDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNYLMTQSMIQDHKNYSHIPHPDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERLHGISSDSSGYETLNRSNCKISNEDEINMYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 4016
            S P G+     + +DSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSC SESERKKW+SVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQ HLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLL EMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPD+TEPVGVSYSHSYHD NGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGN+LMTQSMIQDHKNYSHIPH DSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIER+HGISSDSSGYETLNRSNCKISNEDEIN+YDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH
Sbjct:   13 SDPVGYR----SQYDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDITEPVGVSYSHSYHDTNGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNHLMTQSMIQDHKNYSHIPHSDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERVHGISSDSSGYETLNRSNCKISNEDEINIYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 1144

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1)

HSP 1 Score: 2132.45 bits (5524), Expect = 0.000e+0
Identity = 1098/1136 (96.65%), Postives = 1106/1136 (97.36%), Query Frame = 3

Query:  609 SKPSGFNLSKTASHDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENXXXXXXXXXXXXXXXXAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDVTEPVGVSYSHSYHDXXXXXXXXXXXXDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNYLMTQSMIQDHKNYSHIPHPDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERLHGISSDSSGYETLNRSNCKISNEDEINMYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 4016
            S P G+     + +DSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSC SESERKKW+SVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQ HLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLL EMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPD+TEPVGVSYSHSYHD NGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGN+LMTQSMIQDHKNYSHIPH DSIYREQVDKEWKEM                 KPKIER+HGISSDSSGYETLNRSNCKISNEDEIN+YDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH
Sbjct:   13 SDPVGYR----SQYDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDITEPVGVSYSHSYHDTNGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNHLMTQSMIQDHKNYSHIPHSDSIYREQVDKEWKEM-----------------KPKIERVHGISSDSSGYETLNRSNCKISNEDEINIYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 1127

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1)

HSP 1 Score: 2125.9 bits (5507), Expect = 0.000e+0
Identity = 1095/1136 (96.39%), Postives = 1102/1136 (97.01%), Query Frame = 3

Query:  609 SKPSGFNLSKTASHDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCFSESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENXXXXXXXXXXXXXXXXAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDVTEPVGVSYSHSYHDXXXXXXXXXXXXDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNYLMTQSMIQDHKNYSHIPHPDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERLHGISSDSSGYETLNRSNCKISNEDEINMYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 4016
            S P G+     + +DSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSC SESERKKW+SVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQ HLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLL EMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPD+TEPVGVSYSHSYHD NGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGN+LMTQSMIQDHKNYSHIPH DSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIER+HGISSDSSGYETLNRSN                     FKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH
Sbjct:   13 SDPVGYR----SQYDSCLDQIEEAYINDDCPSVGGKYSKSNSNRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDNPTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPLLKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPTGTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCSSESERKKWMSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDITEPVGVSYSHSYHDTNGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNHLMTQSMIQDHKNYSHIPHSDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERVHGISSDSSGYETLNRSN--------------------FFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 1124

[Close]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Planmine SMEST
Match: SMESG000037132.1 (SMESG000037132.1)

HSP 1 Score: 1692.17 bits (4381), Expect = 0.000e+0
Identity = 876/886 (98.87%), Postives = 881/886 (99.44%), Query Frame = 3

Query: 1359 SVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAXXXXXXXXDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHXXXXXXXXXXXXXXXXXXXXXMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENXXXXXXXXXXXXXXXXAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDVTEPVGVSYSHSYHDXXXXXXXXXXXXDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNYLMTQSMIQDHKNYSHIPHPDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERLHGISSDSSGYETLNRSNCKISNEDEINMYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 4016
            + LTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQ HLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLL EMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPD+TEPVGVSYSHSYHD NGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGN+LMTQSMIQDHKNYSHIPH DSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIER+HGISSDSSGYETLNRSNCKISNEDEIN+YDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH
Sbjct:   71 ATLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIYLDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKKKKSQQHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSIISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPINKYSHLLEFLKQHAVQLLQEMDAHLKVKNKEDLAISLINVLHKQGIAAEFLSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVNRISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQESLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQSNLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQSLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKWNEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPVQKYTGNIEMLINIIADINERLSAKPDITEPVGVSYSHSYHDTNGQQGVEVVQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTYIDRDSTSGNHLMTQSMIQDHKNYSHIPHSDSIYREQVDKEWKEMVSESTYYHKISNINDKKKPKIERVHGISSDSSGYETLNRSNCKISNEDEINIYDKLPLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSSSIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISLPSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRH 956

The following BLAST results are available for this feature:

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Human
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Celegans
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Fly
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Zebrafish
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Xenopus
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Mouse
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. UniProt/SwissProt
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. TrEMBL
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Cavefish
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Sea Lamprey
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Yeast
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Nematostella
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Medaka
BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Planmine SMEST

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DAB2IP	3.454e-94	39.27	DAB2 interacting protein [Source:HGNC Symbol;Acc:H...	[more]
DAB2IP	3.564e-94	39.27	DAB2 interacting protein [Source:HGNC Symbol;Acc:H...	[more]
DAB2IP	7.453e-94	39.27	DAB2 interacting protein [Source:HGNC Symbol;Acc:H...	[more]
DAB2IP	8.409e-94	39.27	DAB2 interacting protein [Source:HGNC Symbol;Acc:H...	[more]
DAB2IP	1.027e-93	39.27	DAB2 interacting protein [Source:HGNC Symbol;Acc:H...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gap-2	2.824e-98	38.58	Ras GTPase-activating protein gap-2 [Source:UniPr...	[more]
gap-2	3.323e-98	38.58	Ras GTPase-activating protein gap-2 [Source:UniPr...	[more]
gap-2	7.274e-98	38.58	Ras GTPase-activating protein gap-2 [Source:UniPr...	[more]
gap-2	1.360e-97	38.58	Ras GTPase-activating protein gap-2 [Source:UniPr...	[more]
gap-2	2.090e-97	38.58	Ras GTPase-activating protein gap-2 [Source:UniPr...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
raskol	4.160e-87	34.01	gene:FBgn0261570 transcript:FBtr0302836	[more]
raskol	5.179e-87	34.14	gene:FBgn0261570 transcript:FBtr0340629	[more]
raskol	1.119e-86	34.01	gene:FBgn0261570 transcript:FBtr0302834	[more]
raskol	1.257e-86	34.01	gene:FBgn0261570 transcript:FBtr0340631	[more]
raskol	1.270e-86	34.01	gene:FBgn0261570 transcript:FBtr0302835	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dab2ipa	1.005e-93	39.47	DAB2 interacting protein a [Source:ZFIN;Acc:ZDB-GE...	[more]
dab2ipa	1.154e-93	39.47	DAB2 interacting protein a [Source:ZFIN;Acc:ZDB-GE...	[more]
dab2ipb	5.833e-92	39.07	DAB2 interacting protein b [Source:ZFIN;Acc:ZDB-GE...	[more]
dab2ipb	8.953e-92	39.07	DAB2 interacting protein b [Source:ZFIN;Acc:ZDB-GE...	[more]
dab2ipb	1.499e-91	39.07	DAB2 interacting protein b [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DAB2IP	1.216e-93	40.08	DAB2 interacting protein [Source:NCBI gene;Acc:100...	[more]
DAB2IP	1.618e-93	40.08	DAB2 interacting protein [Source:NCBI gene;Acc:100...	[more]
DAB2IP	1.975e-93	40.08	DAB2 interacting protein [Source:NCBI gene;Acc:100...	[more]
DAB2IP	2.022e-93	40.08	DAB2 interacting protein [Source:NCBI gene;Acc:100...	[more]
DAB2IP	2.228e-93	40.08	DAB2 interacting protein [Source:NCBI gene;Acc:100...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dab2ip	1.585e-94	39.07	disabled 2 interacting protein [Source:MGI Symbol;...	[more]
Dab2ip	2.227e-94	39.07	disabled 2 interacting protein [Source:MGI Symbol;...	[more]
Dab2ip	2.426e-94	39.07	disabled 2 interacting protein [Source:MGI Symbol;...	[more]
Dab2ip	2.612e-94	39.07	disabled 2 interacting protein [Source:MGI Symbol;...	[more]
Dab2ip	3.622e-94	39.07	disabled 2 interacting protein [Source:MGI Symbol;...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8MLZ5\|GAP2_CAEEL	1.219e-95	38.58	Ras GTPase-activating protein gap-2 OS=Caenorhabdi...	[more]
sp\|Q3UHC7\|DAB2P_MOUSE	3.697e-93	39.07	Disabled homolog 2-interacting protein OS=Mus musc...	[more]
sp\|Q5VWQ8\|DAB2P_HUMAN	4.930e-93	39.27	Disabled homolog 2-interacting protein OS=Homo sap...	[more]
sp\|Q6P730\|DAB2P_RAT	8.736e-88	38.83	Disabled homolog 2-interacting protein OS=Rattus n...	[more]
sp\|Q9UJF2\|NGAP_HUMAN	1.002e-86	38.06	Ras GTPase-activating protein nGAP OS=Homo sapiens...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
V4ANY2	7.230e-101	37.87	Uncharacterized protein (Fragment) OS=Lottia gigan...	[more]
A0A3Q1GA50	5.092e-99	39.07	Uncharacterized protein OS=Acanthochromis polyacan...	[more]
A0A3Q1ER52	5.931e-98	39.27	Uncharacterized protein OS=Acanthochromis polyacan...	[more]
A0A3S2UDU6	6.827e-98	38.87	Uncharacterized protein OS=Oryzias javanicus OX=12...	[more]
A0A3B3DB07	1.331e-97	38.87	Uncharacterized protein OS=Oryzias melastigma OX=3...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dab2ipb	6.773e-95	39.47	DAB2 interacting protein [Source:NCBI gene;Acc:103...	[more]
dab2ipb	1.188e-94	39.47	DAB2 interacting protein [Source:NCBI gene;Acc:103...	[more]
dab2ipb	2.210e-94	39.47	DAB2 interacting protein [Source:NCBI gene;Acc:103...	[more]
dab2ipb	1.535e-93	39.47	DAB2 interacting protein [Source:NCBI gene;Acc:103...	[more]
dab2ipb	1.198e-92	39.27	DAB2 interacting protein [Source:NCBI gene;Acc:103...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000000945.1	1.779e-81	37.07	pep scaffold:Pmarinus_7.0:GL477254:323984:383899:1...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
BUD2	1.215e-17	27.11	GTPase activating factor for Rsr1p/Bud1p; plays a ...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO35799	1.321e-80	35.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36190	1.932e-26	25.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43446	3.382e-26	29.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40933	1.424e-11	28.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000022035.2	5.066e-101	38.87	disabled homolog 2-interacting protein-like [Sourc...	[more]
dab2ipb	2.462e-93	39.68	DAB2 interacting protein [Source:NCBI gene;Acc:101...	[more]
dab2ipb	3.482e-93	39.68	DAB2 interacting protein [Source:NCBI gene;Acc:101...	[more]
dab2ipb	3.610e-93	39.68	DAB2 interacting protein [Source:NCBI gene;Acc:101...	[more]
dab2ipb	4.254e-93	39.68	DAB2 interacting protein [Source:NCBI gene;Acc:101...	[more]

BLAST of ras GTPase-activating protein nGAP isoform X8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000037132.1	0.000e+0	99.13	SMESG000037132.1	[more]
SMESG000037132.1	0.000e+0	98.15	SMESG000037132.1	[more]
SMESG000037132.1	0.000e+0	96.65	SMESG000037132.1	[more]
SMESG000037132.1	0.000e+0	96.39	SMESG000037132.1	[more]
SMESG000037132.1	0.000e+0	98.87	SMESG000037132.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017175 ID=SMED30017175|Name=ras GTPase-activating protein nGAP isoform X8|organism=Schmidtea mediterranea sexual|type=transcript|length=4815bp
AAAAATTTCATTTTAACATTTTCTAAATATTCAACAATAATTCCAATCGA
TATAAACAATAAATTGCACAATGTTTTCACACATTCAATCGAATGGCAAT
TACAAATTATGCCGTCGTCCTCGTCGTCGTCAATGCACGTGTTGGCTCAC
TATTAATAATATATTTATGCAAAAACTTCTCTCTCATTATTTCTAGCAAT
TTCTCAGCTGGTCAACACAAATGTTAGAATATCATCCAGGAATTTATGTT
CACAAATCATCGCAATTGTCAAAATGTTTAATAAAAGAAATTATTGCAAT
AATCAACTGACAGTAATATGCAGTGCCATTGTTGTCCCATACTTGTTGGA
ACACTTTCAATTTCACAGCCGGGATGTTTCGATGTGTGCGTGTGAGTGTG
TCTACGTGTGACAATACTATGCTAGTAGGTGTGCCACTCTTTTGATTGGC
AGCAGTCATTATTCCCACTTCCTATTATAACCTGCAAATGAATGGGTGTT
CCAATATTTTTTAATACATATTTACCTTATTATTTTACTGTATAATCGAT
TGGAGCACTTGAATAGCAAAAGTTTCATCAAGAAATGAAATCCCAGCAAC
GAACGTATTCCAAGCCCTCTGGATTCAATTTGTCAAAAACAGCTTCCCAT
GATTCCTGCCTGGATCAAATAGAGGAGGCATACATTAACGATGACTGCCC
TAGTGTGGGGGGCAAATATTCAAAATCAAATTCAAACAGGCGGTTCACGA
TGACTATGGCTTCATCTCGGTCATCCTTATTGGATATCAGCAAGCCGCAA
GCATCCAGTAGCCAACGATTTCTAGCCTTCATTCAGAAAGGTATCCATGG
CAGCAGAAACAAATCCATCAACAAATTAGATAATCCGACCTTTATCAAAA
TTGTAAATGAAAAGAAATACTTAGAAGCTCTAAATGAGGTCGTTCCTATT
CCGATTCGCGAAACTGCCATTCAAGGCCATTCTAAAATTCTCTTTCACAA
GATCCCAAAGTCAAATGTAAGACCAAGACCCCTGTTGAAACTTGGTGAAG
AGACTAAATTCGTTCTGATACATCCGAGTCTTCTGTCAAAAAATATTCAT
CATTGTGTAAAAATAGTGTCGTTATCACCGAGCATTTACAGGAACTGCAG
TTCTGGAAATCAGTACGAATTATTACTGCCAACGGGAACGCGTTCACTTG
GCCATACGTGCCAGATTATCGGAACCAAGAAATTGCAGGAACAATGCCCA
AGTTGCAATTCATCTCGGCTATCGTTATTTGCATCAGCGGAACAGCAAAA
TCATTTATTGGCCTACGTATTCTCATGCTTCAGCGAATCTGAAAGAAAAA
AATGGCTGAGCGTATTGACTCGAGTTGTCAGGCCAAACCTACAGAATGAA
CGCAGGCAGGAAATATCCCTAAACTTATGGATCCAGGAGGCCAAAAATGT
CCCTTTAAAGAAAAGATATTTCTGTGAGATTTATCTTGATGAAACTTTGC
ACGCAAAAACTACAACTAAGACAATGACAGACTTACTTTTCTGGGGCGAG
GAATTCAATTTATGCCATTTGGAACAAGTGAACACAGTCACCATTCTGCT
CTGGAAGGCTTCCAGTGACAACAGAGCCAAAAAGAAAAAGTCGCAACATC
ATCTAATTTGTCAGGTAAATATCGAAACCAAAGATATTTCAGCTCGAAAC
AATGTTGAAAGGTGGTATCCAGCGTCATGCAGTTATAATTCAAGCGGTAC
AGAAATTGTCCACTCAAATATGTCACATTCTATCATTTCTTCAACCGATT
CAACTCCTACATCCACCCTCCAATCAATGCATTCTACGAATCTCAGTCAG
TCAACCGCGTCGCTAAGCAATAGTGATCACTTGCCAATGATCAGGATCAA
AGCTCGATATCAGAATATCGATGTGCTGCCAATCAATAAATATTCACATC
TCTTAGAATTTCTCAAACAGCATGCCGTTCAATTGCTTCATGAAATGGAC
GCTCACTTAAAAGTTAAAAATAAAGAAGACTTAGCGATTAGTCTCATAAA
TGTTTTGCATAAACAAGGTATTGCGGCAGAATTCCTCAGTGACCTCTTAT
TTCAAGAAATCAAAAAATCAGATAATGAAAACATGATTTTGAGAGGAAAT
ACTATAGCTTCTAAAGCAATTGAAGTATATTTGAAATTGATAGGAGAAAA
ATATTTAAGCCTGATTTTGTCAGATTTTGTTAACAGAATATCTCAAGGAG
ATGAGGACTGCGAAGTTGATCCACAAAGGTCAAAATGCGAATTTTTCAGT
AATTCTTCTTTGAATGAATGTCAATCCTTGCAGAATGGCGATAAATCCAG
TCATTTTCACCCAATGCTCTTGCAGAGACAAGAAAGTCTAATGATGAATG
TTGACATGATTTGGGCCAAAATCTTGAGTAGTTCTATTTATTTTCCAAGG
GAGCTGAAATCTGTGTTTGTATCACTGAGGAAAAGACTTGAACAAATGGA
CCGGACCGCCAATCAAATGGATAATTCGCAATCTAATCTTTATGAACGCA
TTGTTTCTTCCTGTATTTTCCTTAGATTCATTTGTCCAGCTATTTTGACT
CCATCATTATTTGGACTTCTACCAGAATACCCAGATAATCCAAAAGTTTT
AAGAACATTTACTCTTGTTGCTAAATGTATACAAAGCTTGGCCAATTTCT
CAGACCTCACGGGATCTAAGGAATCCTACATGCTGTTTATGAATACTTTC
ATTGAAAATAAGTTCACCACCATGCAATCTTTCCTGAAAGAAATATCCTC
ATCAACCGATGATGACTACTCTAGGTCAAAATGGAATGAACCAAGTTCTG
TTGATGCTTCCAAAGAAAACGGAGGATATTGGGAAAATTTGAGCAGCACA
TTGTCTTTGGATTCCATCGATATATCACTCTGTTTAGCTAAACTTCATCG
ACAATTCGAAGAATACCTACAGGTGATCCCTGTACAAAAATATACGGGCA
ACATTGAGATGCTGATAAATATCATCGCCGATATCAATGAGAGACTGTCG
GCCAAACCTGATGTCACTGAACCGGTTGGCGTAAGCTACAGTCATTCATA
TCATGATGTCAATGGTCAGCAAGGTGTGGAAGTAGTACAAAATGATTGTA
ATGAGATCTGCGGGACGCCTACAAGAAACCCAGACATGGACCAGTGCCAC
CATAATGCACAAATTAATCAGCCAAAAAAAATTAAATCTATGAATCTTTC
TTTTTCTACAGAAACTTCACCGATACATACCTATATTGACAGAGATTCGA
CATCTGGAAATTACCTCATGACTCAGTCTATGATCCAGGATCATAAAAAT
TATTCACATATTCCTCATCCTGATAGCATATATCGTGAACAGGTTGACAA
AGAATGGAAAGAAATGGTAAGCGAATCAACTTATTATCACAAGATATCTA
ATATCAACGACAAAAAGAAACCAAAAATTGAAAGGCTTCATGGGATCAGC
AGCGATTCATCAGGATATGAAACTTTGAACCGTTCTAATTGTAAAATTTC
AAATGAGGATGAAATAAATATGTATGACAAACTTCCTTTGTCACCTTCAG
TTTTTAAGCAATCAGTGAAAAAATGCAAGCAGTTTAGGCGAAAAATAGAA
GTGGTACCTAATTCAGATCCTCTAGATGGTTATTATTGTGATGGGGCGCA
ATTAATTGCACTGAGCAGGAACTTCAGGTCAAGCAGCATTGACGAAATGC
CAAATCACACTTTCTATAATGATTTGTTAACCCGTACCGAAGCAATTGAT
AACGGATCTACGGAAACAATTACAACAAATACTGCATCTCGACTGAATGG
AAATAAATATTCAATGAATACATCTATCTCACTACCTTCCTTCAAAATCC
AGGACTCAAATCGTGACTTTTCCCAGTCTTTTACAAATGTCAACCTGGGA
ACTTCGAATGAACATGTTGATAATAAGATCAAAATGAAAGTGACGTCCGA
CAAAATTTCGAGACACCAACTGAAAACCTCTCCGACACTCAATTACAATT
CTGACGCAACATTTCAACGGCTGCTTCTTGCTGACCAGAAAACTGTTGAA
CTAGAACTAGAACGAGTGCGGCTTATGAAGCAAATATGCGATACGGCAGC
GAAATCGAATACCAACTTCGCTTCCGCAGAAATGGAGGAACAAAAGCAGT
TTATCCAACAGCATAATATCAACGGATTTAATGAAGTTTCCAAACTAAAC
CGTTCAAATCAACTTTCTGTTAAAAGGTATCTCGAAATAGCAGAAAATAT
TTTGCTGAATTGTCGAAAAAATCAGATTCCGAAATATTGTGATTTCCAGG
AAAAAGAAAATCTAATTATTCAGATATTTGAGATAAATCAAAGTTTGCAA
AACGCGTTGATCAAAAACATGCAAGGTTTAATTTTCAATTCAGAACCAGA
AAGGCCTGAAAAAATTGCCAGTTACGGGCCCCATCCTTGCACCAGTAATG
CGACAGCTATGATTTCCAACAGAATAATCACCCCTCGGTCATCAGCATCA
AGCAATGTCAATCAAATTTCCCCATCGAAACATTTTTCTATTAACAAGAG
GGATTCCTCATCTCCCCCCTCTGCAGCTGTTATCGAAATCATTGATGCCG
TATGAATTGAAACTAAATGATTTGTTTATTGAAATTTGTTAAATTGCACA
AACTAACATTTAATTTCTGTAAAGATTTTCTTTTTTATTATTTCAGAATA
ATTTAATTTTTTGCTAAACATAAATTTTAATCTCAAATTTAATAAATTCG
GCCGCTAGAAAAGGT

protein sequence of SMED30017175-orf-1

>SMED30017175-orf-1 ID=SMED30017175-orf-1|Name=SMED30017175-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1357bp
MKSQQRTYSKPSGFNLSKTASHDSCLDQIEEAYINDDCPSVGGKYSKSNS
NRRFTMTMASSRSSLLDISKPQASSSQRFLAFIQKGIHGSRNKSINKLDN
PTFIKIVNEKKYLEALNEVVPIPIRETAIQGHSKILFHKIPKSNVRPRPL
LKLGEETKFVLIHPSLLSKNIHHCVKIVSLSPSIYRNCSSGNQYELLLPT
GTRSLGHTCQIIGTKKLQEQCPSCNSSRLSLFASAEQQNHLLAYVFSCFS
ESERKKWLSVLTRVVRPNLQNERRQEISLNLWIQEAKNVPLKKRYFCEIY
LDETLHAKTTTKTMTDLLFWGEEFNLCHLEQVNTVTILLWKASSDNRAKK
KKSQHHLICQVNIETKDISARNNVERWYPASCSYNSSGTEIVHSNMSHSI
ISSTDSTPTSTLQSMHSTNLSQSTASLSNSDHLPMIRIKARYQNIDVLPI
NKYSHLLEFLKQHAVQLLHEMDAHLKVKNKEDLAISLINVLHKQGIAAEF
LSDLLFQEIKKSDNENMILRGNTIASKAIEVYLKLIGEKYLSLILSDFVN
RISQGDEDCEVDPQRSKCEFFSNSSLNECQSLQNGDKSSHFHPMLLQRQE
SLMMNVDMIWAKILSSSIYFPRELKSVFVSLRKRLEQMDRTANQMDNSQS
NLYERIVSSCIFLRFICPAILTPSLFGLLPEYPDNPKVLRTFTLVAKCIQ
SLANFSDLTGSKESYMLFMNTFIENKFTTMQSFLKEISSSTDDDYSRSKW
NEPSSVDASKENGGYWENLSSTLSLDSIDISLCLAKLHRQFEEYLQVIPV
QKYTGNIEMLINIIADINERLSAKPDVTEPVGVSYSHSYHDVNGQQGVEV
VQNDCNEICGTPTRNPDMDQCHHNAQINQPKKIKSMNLSFSTETSPIHTY
IDRDSTSGNYLMTQSMIQDHKNYSHIPHPDSIYREQVDKEWKEMVSESTY
YHKISNINDKKKPKIERLHGISSDSSGYETLNRSNCKISNEDEINMYDKL
PLSPSVFKQSVKKCKQFRRKIEVVPNSDPLDGYYCDGAQLIALSRNFRSS
SIDEMPNHTFYNDLLTRTEAIDNGSTETITTNTASRLNGNKYSMNTSISL
PSFKIQDSNRDFSQSFTNVNLGTSNEHVDNKIKMKVTSDKISRHQLKTSP
TLNYNSDATFQRLLLADQKTVELELERVRLMKQICDTAAKSNTNFASAEM
EEQKQFIQQHNINGFNEVSKLNRSNQLSVKRYLEIAENILLNCRKNQIPK
YCDFQEKENLIIQIFEINQSLQNALIKNMQGLIFNSEPERPEKIASYGPH
PCTSNATAMISNRIITPRSSASSNVNQISPSKHFSINKRDSSSPPSAAVI
EIIDAV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000018	Category 4 cell
PLANA:0000020	protonephridia
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR035892	C2_domain_sf
IPR039360	Ras_GTPase
IPR001849	PH_domain
IPR001936	RasGAP_dom
IPR000008	C2_dom
IPR023152	RasGAP_CS
IPR008936	Rho_GTPase_activation_prot

Vocabulary: **biological process**
Term	Definition
GO:0043087	regulation of GTPase activity
GO:0007165	signal transduction
GO:0046580	negative regulation of Ras protein signal transduction
GO:0007614	short-term memory
GO:0007616	long-term memory
GO:0008285	negative regulation of cell proliferation
GO:0008306	associative learning
GO:0016525	negative regulation of angiogenesis
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0038026	reelin-mediated signaling pathway
GO:0043065	positive regulation of apoptotic process
GO:0043547	positive regulation of GTPase activity

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005096	GTPase activator activity

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm
GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001936	Ras GTPase-activating domain	SMART	SM00323	RasGAP_2	coord: 428..802 e-value: 1.9E-67 score: 240.1
IPR001936	Ras GTPase-activating domain	PFAM	PF00616	RasGAP	coord: 500..704 e-value: 2.6E-29 score: 102.4
IPR001936	Ras GTPase-activating domain	PROSITE	PS50018	RAS_GTPASE_ACTIV_2	coord: 479..704 score: 42.174
None	No IPR available	GENE3D	G3DSA:1.10.506.10		coord: 498..760 e-value: 2.0E-93 score: 315.1
None	No IPR available	GENE3D	G3DSA:1.10.506.20		coord: 448..822 e-value: 2.0E-93 score: 315.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 403..424
None	No IPR available	PANTHER	PTHR10194:SF125	RAS GTPASE-ACTIVATING PROTEIN-RELATED	coord: 205..1220
None	No IPR available	SUPERFAMILY	SSF49562	C2 domain (Calcium/lipid-binding domain, CaLB)	coord: 279..380
IPR000008	C2 domain	PFAM	PF00168	C2	coord: 279..379 e-value: 2.8E-4 score: 21.1
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 258..396 e-value: 3.0E-6 score: 29.1
IPR039360	Ras GTPase-activating protein	PANTHER	PTHR10194	RAS GTPASE-ACTIVATING PROTEINS	coord: 205..1220
IPR023152	Ras GTPase-activating protein, conserved site	PROSITE	PS00509	RAS_GTPASE_ACTIV_1	coord: 659..673
IPR001849	Pleckstrin homology domain	PROSITE	PS50003	PH_DOMAIN	coord: 244..266 score: 6.855
IPR008936	Rho GTPase activation protein	SUPERFAMILY	SSF48350	GTPase activation domain, GAP	coord: 453..769