ETS domain-containing protein

Overview


Name	ETS domain-containing protein
Smed ID	SMED30017161
Length (bp)	1537

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of ETS domain-containing protein (SMED30017161) t-SNE clustered cells

Violin plots show distribution of expression levels for ETS domain-containing protein (SMED30017161) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ETS domain-containing protein (SMED30017161) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ETS domain-containing protein (SMED30017161) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017161

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30017161	SMESG000033317.1	dd_Smed_v4_14712_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30017161	SMESG000033317.1	dd_Smed_v4_14712_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30017161	SMESG000033317.1	dd_Smed_v4_14712_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30017161	SMESG000033317.1	dd_Smed_v4_14712_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30017161	SMESG000033317.1	dd_Smed_v4_14712_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30017161	SMESG000033317.1	dd_Smed_v4_14712_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Human
Match: ETV4 (ETS variant transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3493])

HSP 1 Score: 162.925 bits (411), Expect = 1.053e-46
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:   60 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 151

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Human
Match: ETV4 (ETS variant transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3493])

HSP 1 Score: 165.236 bits (417), Expect = 6.667e-45
Identity = 73/113 (64.60%), Postives = 87/113 (76.99%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSD 844
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L      L   DN   +L    D
Sbjct:  298 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF----SLAFPDNQRPALKAEFD 406

[Close]

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSD 844
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L      L   DN   +L    D
Sbjct:  298 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF----SLAFPDNQRPALKAEFD 406

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Human
Match: ETV4 (ETS variant transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3493])

HSP 1 Score: 164.466 bits (415), Expect = 9.127e-45
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  283 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 374

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Human
Match: ETV4 (ETS variant transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3493])

HSP 1 Score: 165.236 bits (417), Expect = 1.361e-44
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  337 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 428

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Celegans
Match: ets-5 (ETS domain-containing transcription factor ets-5 [Source:UniProtKB/Swiss-Prot;Acc:Q18579])

HSP 1 Score: 115.546 bits (288), Expect = 1.345e-29
Identity = 62/128 (48.44%), Postives = 77/128 (60.16%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSDIEYKSQVHSSSRKKSQKIP 901
            +QLWQFL  LL +  N H I W G + EFKL+DP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF          +  L    N N  LS        S VHS S   +Q +P
Sbjct:   35 IQLWQFLLELLADAVNAHCIAWEGSNGEFKLVDPDEVARKWGERKSKPNMNYDKLSRALRYYYDKNIMTKVQGKRYAYKFDFQGLAQACQSAILTNGGNPNGDLS--------STVHSLSPYTNQVLP 154

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Celegans
Match: ets-5 (ETS domain-containing transcription factor ets-5 [Source:UniProtKB/Swiss-Prot;Acc:Q18579])

HSP 1 Score: 116.701 bits (291), Expect = 1.648e-29
Identity = 62/128 (48.44%), Postives = 77/128 (60.16%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSDIEYKSQVHSSSRKKSQKIP 901
            +QLWQFL  LL +  N H I W G + EFKL+DP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF          +  L    N N  LS        S VHS S   +Q +P
Sbjct:   73 IQLWQFLLELLADAVNAHCIAWEGSNGEFKLVDPDEVARKWGERKSKPNMNYDKLSRALRYYYDKNIMTKVQGKRYAYKFDFQGLAQACQSAILTNGGNPNGDLS--------STVHSLSPYTNQVLP 192

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Celegans
Match: ast-1 (Axon STeering defect [Source:UniProtKB/TrEMBL;Acc:Q22355])

HSP 1 Score: 113.62 bits (283), Expect = 2.734e-27
Identity = 48/79 (60.76%), Postives = 61/79 (77.22%), Query Frame = 2

Query:  521 QLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            QLWQFL  LL + +   +ITW G   EFKL+DP+EVA+ WG +K++P MNYDK+SR+LRYYY+K IM KV G+RY YKF
Sbjct:  215 QLWQFLLELLSDKRYSEVITWEGTQGEFKLVDPDEVARKWGERKSKPNMNYDKMSRALRYYYDKNIMAKVHGKRYAYKF 293

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Celegans
Match: lin-1 (LIN-1 [Source:UniProtKB/TrEMBL;Acc:G5EDL0])

HSP 1 Score: 104.375 bits (259), Expect = 4.477e-24
Identity = 46/83 (55.42%), Postives = 61/83 (73.49%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWT-GKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFIC 763
            + LWQFL  LL   +N  II WT G   EF+LID E VA+ WG +K +P MNYDKLSR+LRYYYEK I++KV G++++Y+F+ 
Sbjct:   24 ITLWQFLLELLQQDQNGDIIEWTRGTDGEFRLIDAEAVARKWGQRKAKPHMNYDKLSRALRYYYEKNIIKKVIGKKFVYRFVT 106

[Close]

Query:  518 LQLWQFLKSLLDNHKNIHIITWT-GKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFIC 763
            + LWQFL  LL   +N  II WT G   EF+LID E VA+ WG +K +P MNYDKLSR+LRYYYEK I++KV G++++Y+F+ 
Sbjct:   24 ITLWQFLLELLQQDQNGDIIEWTRGTDGEFRLIDAEAVARKWGQRKAKPHMNYDKLSRALRYYYEKNIIKKVIGKKFVYRFVT 106

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Fly
Match: Ets96B (gene:FBgn0039225 transcript:FBtr0339254)

HSP 1 Score: 155.221 bits (391), Expect = 1.938e-40
Identity = 69/95 (72.63%), Postives = 79/95 (83.16%), Query Frame = 2

Query:  503 SQKR-SLQLWQFLKSLLDN-HKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            SQ+R SLQLWQFL +LLD    +   I WTG+ +EFKLI+PEEVA+ WGLQKNRPAMNYDKLSRSLRYYYEKGIMQKV GERY+Y+F+CDP  L 
Sbjct:  483 SQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVYRFVCDPDALF 577

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Fly
Match: Ets96B (gene:FBgn0039225 transcript:FBtr0084697)

HSP 1 Score: 154.836 bits (390), Expect = 2.626e-40
Identity = 69/95 (72.63%), Postives = 79/95 (83.16%), Query Frame = 2

Query:  503 SQKR-SLQLWQFLKSLLDN-HKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            SQ+R SLQLWQFL +LLD    +   I WTG+ +EFKLI+PEEVA+ WGLQKNRPAMNYDKLSRSLRYYYEKGIMQKV GERY+Y+F+CDP  L 
Sbjct:  492 SQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVYRFVCDPDALF 586

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Fly
Match: Ets65A (gene:FBgn0005658 transcript:FBtr0077055)

HSP 1 Score: 112.849 bits (281), Expect = 6.442e-28
Identity = 50/80 (62.50%), Postives = 61/80 (76.25%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL +  N   ITW G + EFKL DP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF
Sbjct:   84 IQLWQFLLELLSDSNNASCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 163

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Fly
Match: Ets21C (gene:FBgn0005660 transcript:FBtr0112854)

HSP 1 Score: 114.005 bits (284), Expect = 6.788e-28
Identity = 50/80 (62.50%), Postives = 63/80 (78.75%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL +  N + I+W G+S EF+LIDP+EVA+ WG +K +P MNYDKLSR+LRYYY+K IM KV G+RY YKF
Sbjct:   85 IQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 164

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Fly
Match: Ets65A (gene:FBgn0005658 transcript:FBtr0077054)

HSP 1 Score: 114.775 bits (286), Expect = 4.074e-27
Identity = 50/80 (62.50%), Postives = 61/80 (76.25%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL +  N   ITW G + EFKL DP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF
Sbjct:  317 IQLWQFLLELLSDSNNASCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 396

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Zebrafish
Match: etv4 (ETS variant transcription factor 4 [Source:NCBI gene;Acc:30700])

HSP 1 Score: 167.162 bits (422), Expect = 1.739e-45
Identity = 74/108 (68.52%), Postives = 87/108 (80.56%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSL 829
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L+     L   DN   SL
Sbjct:  346 RRGSLQLWQFLVALLDDPSNAHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALI----SLAFPDNQRPSL 449

[Close]

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSL 829
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L+     L   DN   SL
Sbjct:  346 RRGSLQLWQFLVALLDDPSNAHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALI----SLAFPDNQRPSL 449

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Zebrafish
Match: etv5b (ETS variant transcription factor 5b [Source:ZFIN;Acc:ZDB-GENE-991228-4])

HSP 1 Score: 167.548 bits (423), Expect = 2.471e-45
Identity = 76/113 (67.26%), Postives = 87/113 (76.99%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSD 844
            ++ SLQLWQFL +LLD+  N H ITWTG+ LEFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L      +   DN   SL    D
Sbjct:  373 RRGSLQLWQFLVTLLDDPSNGHFITWTGRGLEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALF----SMAFPDNQRPSLKAEPD 481

[Close]

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSD 844
            ++ SLQLWQFL +LLD+  N H ITWTG+ LEFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L      +   DN   SL    D
Sbjct:  373 RRGSLQLWQFLVTLLDDPSNGHFITWTGRGLEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALF----SMAFPDNQRPSLKAEPD 481

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Zebrafish
Match: etv5b (ETS variant transcription factor 5b [Source:ZFIN;Acc:ZDB-GENE-991228-4])

HSP 1 Score: 166.392 bits (420), Expect = 2.900e-45
Identity = 77/114 (67.54%), Postives = 88/114 (77.19%), Query Frame = 2

Query:  503 SQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSD 844
            ++K SLQLWQFL +LLD+  N H ITWTG+ LEFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L      +   DN   SL    D
Sbjct:  328 TEKGSLQLWQFLVTLLDDPSNGHFITWTGRGLEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALF----SMAFPDNQRPSLKAEPD 437

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000029479.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:10:23638928:23650532:1 gene:ENSXETG00000004517.1 transcript:ENSXETT00000029479.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 165.622 bits (418), Expect = 4.983e-47
Identity = 71/92 (77.17%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLDN  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  136 RRGSLQLWQFLVALLDNPTNSHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 227

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000029485.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:10:23638928:23650532:1 gene:ENSXETG00000004517.1 transcript:ENSXETT00000029485.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 165.236 bits (417), Expect = 1.530e-46
Identity = 71/92 (77.17%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLDN  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  167 RRGSLQLWQFLVALLDNPTNSHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 258

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Xenopus
Match: etv1 (ETS variant transcription factor 1 [Source:NCBI gene;Acc:394827])

HSP 1 Score: 163.696 bits (413), Expect = 1.753e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  291 RRGSLQLWQFLVALLDDPANSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 382

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Xenopus
Match: etv1 (ETS variant transcription factor 1 [Source:NCBI gene;Acc:394827])

HSP 1 Score: 164.081 bits (414), Expect = 2.841e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  328 RRGSLQLWQFLVALLDDPANSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 419

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Xenopus
Match: etv1 (ETS variant transcription factor 1 [Source:NCBI gene;Acc:394827])

HSP 1 Score: 163.696 bits (413), Expect = 3.211e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  323 RRGSLQLWQFLVALLDDPANSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 414

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Mouse
Match: Etv4 (ets variant 4 [Source:MGI Symbol;Acc:MGI:99423])

HSP 1 Score: 165.622 bits (418), Expect = 7.907e-45
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  339 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 430

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Mouse
Match: Etv4 (ets variant 4 [Source:MGI Symbol;Acc:MGI:99423])

HSP 1 Score: 165.236 bits (417), Expect = 8.009e-45
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  338 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 429

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Mouse
Match: Etv4 (ets variant 4 [Source:MGI Symbol;Acc:MGI:99423])

HSP 1 Score: 165.236 bits (417), Expect = 8.110e-45
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  333 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 424

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Mouse
Match: Etv1 (ets variant 1 [Source:MGI Symbol;Acc:MGI:99254])

HSP 1 Score: 163.696 bits (413), Expect = 1.003e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  273 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 364

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Mouse
Match: Etv1 (ets variant 1 [Source:MGI Symbol;Acc:MGI:99254])

HSP 1 Score: 162.155 bits (409), Expect = 1.338e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  228 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 319

[Close]

BLAST of ETS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9PUQ1|ETV4_DANRE (ETS translocation variant 4 OS=Danio rerio OX=7955 GN=etv4 PE=1 SV=2)

HSP 1 Score: 165.622 bits (418), Expect = 4.790e-44
Identity = 68/92 (73.91%), Postives = 82/92 (89.13%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG++KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L+
Sbjct:  346 RRGSLQLWQFLVALLDDPSNAHFIAWTGRGMEFKLIEPEEVARLWGIEKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALI 437

[Close]

BLAST of ETS domain-containing protein vs. UniProt/SwissProt
Match: sp|P28322|ETV4_MOUSE (ETS translocation variant 4 OS=Mus musculus OX=10090 GN=Etv4 PE=2 SV=2)

HSP 1 Score: 165.236 bits (417), Expect = 5.602e-44
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  338 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 429

[Close]

BLAST of ETS domain-containing protein vs. UniProt/SwissProt
Match: sp|P43268|ETV4_HUMAN (ETS translocation variant 4 OS=Homo sapiens OX=9606 GN=ETV4 PE=1 SV=3)

HSP 1 Score: 165.236 bits (417), Expect = 6.537e-44
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  337 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 428

[Close]

BLAST of ETS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9CXC9|ETV5_MOUSE (ETS translocation variant 5 OS=Mus musculus OX=10090 GN=Etv5 PE=2 SV=1)

HSP 1 Score: 164.851 bits (416), Expect = 1.183e-43
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  364 RRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALF 455

[Close]

BLAST of ETS domain-containing protein vs. UniProt/SwissProt
Match: sp|P41161|ETV5_HUMAN (ETS translocation variant 5 OS=Homo sapiens OX=9606 GN=ETV5 PE=1 SV=1)

HSP 1 Score: 164.466 bits (415), Expect = 2.017e-43
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  364 RRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALF 455

[Close]

BLAST of ETS domain-containing protein vs. TrEMBL
Match: A0A0S7M1X7 (ETV5 (Fragment) OS=Poeciliopsis prolifica OX=188132 GN=ETV5 PE=3 SV=1)

HSP 1 Score: 166.007 bits (419), Expect = 1.193e-44
Identity = 72/92 (78.26%), Postives = 83/92 (90.22%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLDN  N H+I WTG+++EFKLIDPEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:   58 RRGSLQLWQFLLTLLDNPANRHLIVWTGRNMEFKLIDPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 149

[Close]

BLAST of ETS domain-containing protein vs. TrEMBL
Match: A0A0P7W6W4 (ETS domain-containing protein OS=Scleropages formosus OX=113540 GN=Z043_123746 PE=3 SV=1)

HSP 1 Score: 164.851 bits (416), Expect = 4.747e-44
Identity = 69/92 (75.00%), Postives = 82/92 (89.13%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L+
Sbjct:   66 RRGSLQLWQFLVALLDDPGNAHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALI 157

[Close]

BLAST of ETS domain-containing protein vs. TrEMBL
Match: M1ELA5 (Ets variant 4 (Fragment) OS=Mustela putorius furo OX=9669 PE=2 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 5.410e-44
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ +LQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:    9 RRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALF 100

[Close]

BLAST of ETS domain-containing protein vs. TrEMBL
Match: A0A5G3J1Q8 (ETS domain-containing protein OS=Xenopus tropicalis OX=8364 PE=3 SV=1)

HSP 1 Score: 165.622 bits (418), Expect = 7.825e-44
Identity = 71/92 (77.17%), Postives = 81/92 (88.04%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLDN  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  136 RRGSLQLWQFLVALLDNPTNSHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 227

[Close]

BLAST of ETS domain-containing protein vs. TrEMBL
Match: A0A1A7YIV8 (Ets variant 5 (Fragment) OS=Iconisemion striatum OX=60296 GN=ETV5 PE=3 SV=1)

HSP 1 Score: 170.244 bits (430), Expect = 1.088e-43
Identity = 72/92 (78.26%), Postives = 83/92 (90.22%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLDN  N H+I WTG+++EFKLIDPEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  346 RRGSLQLWQFLLTLLDNPANAHLIVWTGRNMEFKLIDPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 437

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Cavefish
Match: etv4 (ETS variant transcription factor 4 [Source:NCBI gene;Acc:103042838])

HSP 1 Score: 166.777 bits (421), Expect = 2.561e-45
Identity = 69/92 (75.00%), Postives = 82/92 (89.13%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L+
Sbjct:  354 RRGSLQLWQFLVALLDDPGNAHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALI 445

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Cavefish
Match: etv4 (ETS variant transcription factor 4 [Source:NCBI gene;Acc:103042838])

HSP 1 Score: 167.162 bits (422), Expect = 2.765e-45
Identity = 74/108 (68.52%), Postives = 87/108 (80.56%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSL 829
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L+     L   DN   SL
Sbjct:  372 RRGSLQLWQFLVALLDDPGNAHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALI----SLAFPDNQRPSL 475

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Cavefish
Match: etv1 (ETS variant transcription factor 1 [Source:NCBI gene;Acc:103024366])

HSP 1 Score: 163.696 bits (413), Expect = 1.146e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  286 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 377

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Cavefish
Match: etv1 (ETS variant transcription factor 1 [Source:NCBI gene;Acc:103024366])

HSP 1 Score: 163.696 bits (413), Expect = 1.190e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  291 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 382

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Cavefish
Match: etv5b (ETS translocation variant 5-like [Source:NCBI gene;Acc:103040586])

HSP 1 Score: 164.851 bits (416), Expect = 1.568e-44
Identity = 70/92 (76.09%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ LEFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  355 RRGSLQLWQFLVTLLDDPSNSHFIAWTGRGLEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 446

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Sea Lamprey
Match: etv1 (ETS variant transcription factor 1 [Source:ZFIN;Acc:ZDB-GENE-070104-1])

HSP 1 Score: 162.925 bits (411), Expect = 2.368e-46
Identity = 70/98 (71.43%), Postives = 83/98 (84.69%), Query Frame = 2

Query:  488 NPNRNSQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
             P    ++ SLQLWQFL +LLD+  N H+ITWTG+ +EFKL++PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  155 GPPPYQRRGSLQLWQFLVALLDDPANGHLITWTGRGMEFKLLEPEEVARKWGVQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 252

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002472.1 (pep scaffold:Pmarinus_7.0:GL476893:38150:62026:-1 gene:ENSPMAG00000002241.1 transcript:ENSPMAT00000002472.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 159.844 bits (403), Expect = 9.325e-44
Identity = 67/97 (69.07%), Postives = 81/97 (83.51%), Query Frame = 2

Query:  491 PNRNSQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            P    ++ SLQLWQFL +LL++  +   I WTG+ +EFKL+DPEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C P V+ 
Sbjct:  368 PPVYPRRGSLQLWQFLVALLEDPAHAGTIVWTGRGMEFKLLDPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCHPEVVF 464

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006723.1 (pep scaffold:Pmarinus_7.0:GL483008:681:12314:1 gene:ENSPMAG00000006043.1 transcript:ENSPMAT00000006723.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 159.844 bits (403), Expect = 1.635e-43
Identity = 67/97 (69.07%), Postives = 82/97 (84.54%), Query Frame = 2

Query:  491 PNRNSQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            P    ++ SLQLWQFL +LL++  +   I WTG+ +EFKL+DPEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+Y+F+CDP V+ 
Sbjct:  362 PPMYQRRGSLQLWQFLVALLEDPVHAGTIVWTGRGMEFKLLDPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYRFVCDPEVVF 458

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Sea Lamprey
Match: fev (FEV transcription factor, ETS family member [Source:NCBI gene;Acc:791175])

HSP 1 Score: 112.464 bits (280), Expect = 5.407e-29
Identity = 49/80 (61.25%), Postives = 59/80 (73.75%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL +  N H I W G   EFKL DP+EVA+ WG +K +P MNYDKLSR+LRYYY+K IM KV G+RY Y+F
Sbjct:    6 IQLWQFLLELLSDAANAHCIAWEGACGEFKLTDPDEVARQWGKRKAKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRF 85

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Sea Lamprey
Match: fli1a (Fli-1 proto-oncogene, ETS transcription factor a [Source:ZFIN;Acc:ZDB-GENE-980526-426])

HSP 1 Score: 112.079 bits (279), Expect = 8.213e-29
Identity = 50/86 (58.14%), Postives = 63/86 (73.26%), Query Frame = 2

Query:  500 NSQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            N     +QLWQFL  LL +  N + ITW G + EFK+ DP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF
Sbjct:   28 NPGSGQIQLWQFLLELLSDSSNANCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 113

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Nematostella
Match: EDO37550 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFF5])

HSP 1 Score: 149.058 bits (375), Expect = 2.056e-43
Identity = 71/93 (76.34%), Postives = 78/93 (83.87%), Query Frame = 2

Query:  506 QKR-SLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            Q+R SLQLWQFL +LLD  +    I WTG+ LEFKLIDPEEVA+ WGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C P  L 
Sbjct:    2 QRRGSLQLWQFLVALLDEPECSSFIAWTGRGLEFKLIDPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCSPEALF 94

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Nematostella
Match: EDO39973 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8F6])

HSP 1 Score: 111.309 bits (277), Expect = 1.748e-29
Identity = 49/80 (61.25%), Postives = 63/80 (78.75%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL + KN + I W G + EFKL+DP+EVA+ WG +KN+P MNYDKLSR+LRYYY+K IM K+ G+RY YK+
Sbjct:   15 IQLWQFLLELLSDPKNANCIAWEGTNGEFKLVDPDEVARRWGERKNKPNMNYDKLSRALRYYYDKNIMTKIHGKRYAYKY 94

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Nematostella
Match: EDO43493 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYB7])

HSP 1 Score: 111.309 bits (277), Expect = 1.828e-29
Identity = 49/88 (55.68%), Postives = 67/88 (76.14%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            +QLWQFL  LL +    H+I W G+  EFKL DPE+VA+ WG +KN+PAMNY+KLSR+LRYYY+  ++ KV G+R++YKF+C+   LL
Sbjct:    1 IQLWQFLLELLTDKTCRHLIMWVGEEGEFKLNDPEQVAQQWGKRKNKPAMNYEKLSRALRYYYDGDMIHKVHGKRFVYKFVCNLKNLL 88

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Nematostella
Match: EDO44339 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW27])

HSP 1 Score: 101.679 bits (252), Expect = 2.567e-26
Identity = 49/86 (56.98%), Postives = 67/86 (77.91%), Query Frame = 2

Query:  515 SLQLWQFLKSLLDNHKNIHIITWTGK-SLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDP 769
            ++ LW+FL  LL + +   II+WT + S EFKL++ EEVA+ WG  K+RP MNYDKLSR+LRYYY+KGI++KV G+R +YKF C+P
Sbjct:    2 AIHLWEFLLDLLADGRYSSIISWTNRESGEFKLLNQEEVARRWGHLKHRPGMNYDKLSRALRYYYQKGIIKKVHGQRLVYKF-CNP 86

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Nematostella
Match: EDO43494 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYB8])

HSP 1 Score: 93.2041 bits (230), Expect = 4.641e-23
Identity = 46/89 (51.69%), Postives = 65/89 (73.03%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWT-GKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            +QLWQFL  LL   ++  +I WT  +  EFKL++P  +A +WG +KN+P MNY+KLSR LRYYY+K I+ KV G+RY+Y+F+CD   +L
Sbjct:    5 IQLWQFLLELLLCPQSQRLIEWTYDEKFEFKLLNPPVIATMWGKRKNKPNMNYEKLSRGLRYYYDKNIIDKVHGKRYVYQFVCDIEKIL 93

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Medaka
Match: etv4 (ETS variant transcription factor 4 [Source:NCBI gene;Acc:101173984])

HSP 1 Score: 166.777 bits (421), Expect = 3.177e-45
Identity = 69/92 (75.00%), Postives = 82/92 (89.13%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L+
Sbjct:  371 RRGSLQLWQFLVALLDDPGNAHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALI 462

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028958.1 (ETS translocation variant 5-like [Source:NCBI gene;Acc:101164024])

HSP 1 Score: 164.851 bits (416), Expect = 7.761e-45
Identity = 70/92 (76.09%), Postives = 82/92 (89.13%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLDN  N H+I WTG+++EFKL DPEEVA+LWG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+C+P  L 
Sbjct:  319 RRGSLQLWQFLLTLLDNPGNAHLIVWTGRNMEFKLNDPEEVARLWGVQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCNPEALF 410

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Medaka
Match: etv1 (ETS variant transcription factor 1 [Source:NCBI gene;Acc:101169639])

HSP 1 Score: 162.54 bits (410), Expect = 8.595e-45
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  228 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 319

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Medaka
Match: etv5a (ETS translocation variant 5 [Source:NCBI gene;Acc:101165293])

HSP 1 Score: 164.851 bits (416), Expect = 1.283e-44
Identity = 73/113 (64.60%), Postives = 87/113 (76.99%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSD 844
            ++ SLQLWQFL +LLD+  N + I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L      +   DN   SL +  D
Sbjct:  356 RRGSLQLWQFLVTLLDDPANAYFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF----SMAFPDNQRPSLKVDPD 464

[Close]

BLAST of ETS domain-containing protein vs. Ensembl Medaka
Match: etv1 (ETS variant transcription factor 1 [Source:NCBI gene;Acc:101169639])

HSP 1 Score: 162.925 bits (411), Expect = 2.110e-44
Identity = 69/92 (75.00%), Postives = 80/92 (86.96%), Query Frame = 2

Query:  506 QKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLL 781
            ++ SLQLWQFL +LLD+  N H I WTG+ +EFKLI+PEEVA+ WG+QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERY+YKF+CDP  L 
Sbjct:  292 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALF 383

[Close]

BLAST of ETS domain-containing protein vs. Planmine SMEST
Match: SMESG000033317.1 (SMESG000033317.1)

HSP 1 Score: 823.928 bits (2127), Expect = 0.000e+0
Identity = 457/458 (99.78%), Postives = 458/458 (100.00%), Query Frame = 2

Query:   74 MSVGDVNFIWHGINKSTEVDLTCHHGYCVCDESGXXXXXXXXXXXXVTQSNPGEYISERKSTKIYERENEQIHQNFNSINILQSYDHANNNHSQSEILTTFQTEIQETDPQSRNCSPNFSVKTNEEXXXXXXXXXXXXNPNRNSQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSDIEYKSQVHSSSRKKSQKIPNPNIKKRSQLPKKNSKLLNLQKYQNSVSDSLEMLKKSDEFLQFPLSIEQTKYNSPNVNYKPYPHFRFPESETVNSSSNNPNQSDHRDFSSSLDSFKKYCSNNCTPTSQTSDFTMPSYGVYEHLLPGGXXXXXXXXXXXXXXXXQDCNYVPQLSNYQIWDQHYPNKFQNSQVNQYWLRNYCDF 1447
            MSVGDVNFIWHGINKSTEVDLTCHHGYCVCDESGNNSNNNSTIITNVTQSNPGEYISERKSTKIYERENEQIHQNFNSINILQSYDHANNNHSQSEILTTFQTEIQETDPQSRNCSPNFSVKTNEESLDSLKTDSLSTNPNRNSQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSDIEYKSQVHSSSRKKSQKIPNPNIKKRSQLPKKNS+LLNLQKYQNSVSDSLEMLKKSDEFLQFPLSIEQTKYNSPNVNYKPYPHFRFPESETVNSSSNNPNQSDHRDFSSSLDSFKKYCSNNCTPTSQTSDFTMPSYGVYEHLLPGGIPNISPPYSIIPTPSIQDCNYVPQLSNYQIWDQHYPNKFQNSQVNQYWLRNYCDF
Sbjct:    1 MSVGDVNFIWHGINKSTEVDLTCHHGYCVCDESGNNSNNNSTIITNVTQSNPGEYISERKSTKIYERENEQIHQNFNSINILQSYDHANNNHSQSEILTTFQTEIQETDPQSRNCSPNFSVKTNEESLDSLKTDSLSTNPNRNSQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNKSLSLSSDIEYKSQVHSSSRKKSQKIPNPNIKKRSQLPKKNSRLLNLQKYQNSVSDSLEMLKKSDEFLQFPLSIEQTKYNSPNVNYKPYPHFRFPESETVNSSSNNPNQSDHRDFSSSLDSFKKYCSNNCTPTSQTSDFTMPSYGVYEHLLPGGIPNISPPYSIIPTPSIQDCNYVPQLSNYQIWDQHYPNKFQNSQVNQYWLRNYCDF 458

[Close]

BLAST of ETS domain-containing protein vs. Planmine SMEST
Match: SMESG000008885.1 (SMESG000008885.1)

HSP 1 Score: 134.806 bits (338), Expect = 1.154e-34
Identity = 62/95 (65.26%), Postives = 76/95 (80.00%), Query Frame = 2

Query:  503 SQKRSLQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKFI--CDPSVLL 781
            +++ + QLWQFL SLL + ++  +I WTG+  EFKLI+PEEVA+LWG QKNRPAMNYDKLSRSLRYYY+K IMQKV GERY+YKF   C P  +L
Sbjct:  181 AERGNPQLWQFLLSLLHDSRHSRVICWTGRDKEFKLIEPEEVARLWGAQKNRPAMNYDKLSRSLRYYYDKNIMQKVPGERYVYKFTDNCLPDNIL 275

[Close]

BLAST of ETS domain-containing protein vs. Planmine SMEST
Match: SMESG000078333.1 (SMESG000078333.1)

HSP 1 Score: 117.087 bits (292), Expect = 1.348e-28
Identity = 51/80 (63.75%), Postives = 63/80 (78.75%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL + +N   ITW G + EFKLIDP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF
Sbjct:   78 IQLWQFLLELLSDSRNTTFITWEGTNGEFKLIDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 157

[Close]

BLAST of ETS domain-containing protein vs. Planmine SMEST
Match: SMESG000078333.1 (SMESG000078333.1)

HSP 1 Score: 117.087 bits (292), Expect = 1.429e-28
Identity = 51/80 (63.75%), Postives = 63/80 (78.75%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL + +N   ITW G + EFKLIDP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF
Sbjct:   81 IQLWQFLLELLSDSRNTTFITWEGTNGEFKLIDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 160

[Close]

BLAST of ETS domain-containing protein vs. Planmine SMEST
Match: SMESG000080027.1 (SMESG000080027.1)

HSP 1 Score: 116.701 bits (291), Expect = 5.374e-28
Identity = 50/80 (62.50%), Postives = 63/80 (78.75%), Query Frame = 2

Query:  518 LQLWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYMYKF 757
            +QLWQFL  LL + +NI  I W G + EFKL+DP+EVA+ WG +K++P MNYDKLSR+LRYYY+K IM KV G+RY YKF
Sbjct:  138 IQLWQFLLELLSDSRNISCIIWEGTNGEFKLVDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYKF 217

The following BLAST results are available for this feature:

BLAST of ETS domain-containing protein vs. Ensembl Human
BLAST of ETS domain-containing protein vs. Ensembl Celegans
BLAST of ETS domain-containing protein vs. Ensembl Fly
BLAST of ETS domain-containing protein vs. Ensembl Zebrafish
BLAST of ETS domain-containing protein vs. Ensembl Xenopus
BLAST of ETS domain-containing protein vs. Ensembl Mouse
BLAST of ETS domain-containing protein vs. UniProt/SwissProt
BLAST of ETS domain-containing protein vs. TrEMBL
BLAST of ETS domain-containing protein vs. Ensembl Cavefish
BLAST of ETS domain-containing protein vs. Ensembl Sea Lamprey
BLAST of ETS domain-containing protein vs. Ensembl Yeast
BLAST of ETS domain-containing protein vs. Ensembl Nematostella
BLAST of ETS domain-containing protein vs. Ensembl Medaka
BLAST of ETS domain-containing protein vs. Planmine SMEST

BLAST of ETS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ETV4	1.053e-46	73.91	ETS variant transcription factor 4 [Source:HGNC Sy...	[more]
ETV4	6.667e-45	64.60	ETS variant transcription factor 4 [Source:HGNC Sy...	[more]
ETV4	6.667e-45	64.60	ETS variant transcription factor 4 [Source:HGNC Sy...	[more]
ETV4	9.127e-45	73.91	ETS variant transcription factor 4 [Source:HGNC Sy...	[more]
ETV4	1.361e-44	73.91	ETS variant transcription factor 4 [Source:HGNC Sy...	[more]

BLAST of ETS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ets-5	1.345e-29	48.44	ETS domain-containing transcription factor ets-5 ...	[more]
ets-5	1.648e-29	48.44	ETS domain-containing transcription factor ets-5 ...	[more]
ast-1	2.734e-27	60.76	Axon STeering defect [Source:UniProtKB/TrEMBL;Acc...	[more]
lin-1	4.477e-24	55.42	LIN-1 [Source:UniProtKB/TrEMBL;Acc:G5EDL0]	[more]
lin-1	4.477e-24	55.42	LIN-1 [Source:UniProtKB/TrEMBL;Acc:G5EDL0]	[more]

BLAST of ETS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ets96B	1.938e-40	72.63	gene:FBgn0039225 transcript:FBtr0339254	[more]
Ets96B	2.626e-40	72.63	gene:FBgn0039225 transcript:FBtr0084697	[more]
Ets65A	6.442e-28	62.50	gene:FBgn0005658 transcript:FBtr0077055	[more]
Ets21C	6.788e-28	62.50	gene:FBgn0005660 transcript:FBtr0112854	[more]
Ets65A	4.074e-27	62.50	gene:FBgn0005658 transcript:FBtr0077054	[more]

BLAST of ETS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
etv4	1.739e-45	68.52	ETS variant transcription factor 4 [Source:NCBI ge...	[more]
etv4	1.739e-45	68.52	ETS variant transcription factor 4 [Source:NCBI ge...	[more]
etv5b	2.471e-45	67.26	ETS variant transcription factor 5b [Source:ZFIN;A...	[more]
etv5b	2.471e-45	67.26	ETS variant transcription factor 5b [Source:ZFIN;A...	[more]
etv5b	2.900e-45	67.54	ETS variant transcription factor 5b [Source:ZFIN;A...	[more]

BLAST of ETS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000029479.1	4.983e-47	77.17	pep primary_assembly:Xenopus_tropicalis_v9.1:10:23...	[more]
ENSXETT00000029485.1	1.530e-46	77.17	pep primary_assembly:Xenopus_tropicalis_v9.1:10:23...	[more]
etv1	1.753e-44	75.00	ETS variant transcription factor 1 [Source:NCBI ge...	[more]
etv1	2.841e-44	75.00	ETS variant transcription factor 1 [Source:NCBI ge...	[more]
etv1	3.211e-44	75.00	ETS variant transcription factor 1 [Source:NCBI ge...	[more]

BLAST of ETS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Etv4	7.907e-45	73.91	ets variant 4 [Source:MGI Symbol;Acc:MGI:99423]	[more]
Etv4	8.009e-45	73.91	ets variant 4 [Source:MGI Symbol;Acc:MGI:99423]	[more]
Etv4	8.110e-45	73.91	ets variant 4 [Source:MGI Symbol;Acc:MGI:99423]	[more]
Etv1	1.003e-44	75.00	ets variant 1 [Source:MGI Symbol;Acc:MGI:99254]	[more]
Etv1	1.338e-44	75.00	ets variant 1 [Source:MGI Symbol;Acc:MGI:99254]	[more]

BLAST of ETS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9PUQ1\|ETV4_DANRE	4.790e-44	73.91	ETS translocation variant 4 OS=Danio rerio OX=7955...	[more]
sp\|P28322\|ETV4_MOUSE	5.602e-44	73.91	ETS translocation variant 4 OS=Mus musculus OX=100...	[more]
sp\|P43268\|ETV4_HUMAN	6.537e-44	73.91	ETS translocation variant 4 OS=Homo sapiens OX=960...	[more]
sp\|Q9CXC9\|ETV5_MOUSE	1.183e-43	75.00	ETS translocation variant 5 OS=Mus musculus OX=100...	[more]
sp\|P41161\|ETV5_HUMAN	2.017e-43	75.00	ETS translocation variant 5 OS=Homo sapiens OX=960...	[more]

BLAST of ETS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0S7M1X7	1.193e-44	78.26	ETV5 (Fragment) OS=Poeciliopsis prolifica OX=18813...	[more]
A0A0P7W6W4	4.747e-44	75.00	ETS domain-containing protein OS=Scleropages formo...	[more]
M1ELA5	5.410e-44	73.91	Ets variant 4 (Fragment) OS=Mustela putorius furo ...	[more]
A0A5G3J1Q8	7.825e-44	77.17	ETS domain-containing protein OS=Xenopus tropicali...	[more]
A0A1A7YIV8	1.088e-43	78.26	Ets variant 5 (Fragment) OS=Iconisemion striatum O...	[more]

BLAST of ETS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
etv4	2.561e-45	75.00	ETS variant transcription factor 4 [Source:NCBI ge...	[more]
etv4	2.765e-45	68.52	ETS variant transcription factor 4 [Source:NCBI ge...	[more]
etv1	1.146e-44	75.00	ETS variant transcription factor 1 [Source:NCBI ge...	[more]
etv1	1.190e-44	75.00	ETS variant transcription factor 1 [Source:NCBI ge...	[more]
etv5b	1.568e-44	76.09	ETS translocation variant 5-like [Source:NCBI gene...	[more]

BLAST of ETS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
etv1	2.368e-46	71.43	ETS variant transcription factor 1 [Source:ZFIN;Ac...	[more]
ENSPMAT00000002472.1	9.325e-44	69.07	pep scaffold:Pmarinus_7.0:GL476893:38150:62026:-1 ...	[more]
ENSPMAT00000006723.1	1.635e-43	69.07	pep scaffold:Pmarinus_7.0:GL483008:681:12314:1 gen...	[more]
fev	5.407e-29	61.25	FEV transcription factor, ETS family member [Sourc...	[more]
fli1a	8.213e-29	58.14	Fli-1 proto-oncogene, ETS transcription factor a [...	[more]

BLAST of ETS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of ETS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37550	2.056e-43	76.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39973	1.748e-29	61.25	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43493	1.828e-29	55.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44339	2.567e-26	56.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43494	4.641e-23	51.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of ETS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
etv4	3.177e-45	75.00	ETS variant transcription factor 4 [Source:NCBI ge...	[more]
ENSORLT00000028958.1	7.761e-45	76.09	ETS translocation variant 5-like [Source:NCBI gene...	[more]
etv1	8.595e-45	75.00	ETS variant transcription factor 1 [Source:NCBI ge...	[more]
etv5a	1.283e-44	64.60	ETS translocation variant 5 [Source:NCBI gene;Acc:...	[more]
etv1	2.110e-44	75.00	ETS variant transcription factor 1 [Source:NCBI ge...	[more]

BLAST of ETS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000033317.1	0.000e+0	99.78	SMESG000033317.1	[more]
SMESG000008885.1	1.154e-34	65.26	SMESG000008885.1	[more]
SMESG000078333.1	1.348e-28	63.75	SMESG000078333.1	[more]
SMESG000078333.1	1.429e-28	63.75	SMESG000078333.1	[more]
SMESG000080027.1	5.374e-28	62.50	SMESG000080027.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017161 ID=SMED30017161|Name=ETS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1537bp
TTTTACGGTTTTAACGACATCCGCTCTATTCTTGATTCATTATTCGGAAT
AATTTTTTAACATTTCCGGCATAATGTCAGTAGGTGACGTTAATTTCATT
TGGCATGGTATAAATAAATCAACGGAAGTTGATTTGACGTGTCACCATGG
TTACTGTGTATGTGACGAAAGCGGAAATAATAGTAATAACAATTCAACAA
TAATTACTAATGTTACCCAGTCTAATCCCGGAGAATATATTTCTGAAAGA
AAATCAACAAAAATATATGAACGGGAAAACGAACAAATCCACCAAAATTT
CAATTCCATCAACATTTTACAGTCGTATGATCATGCAAATAATAATCACA
GTCAATCAGAGATCTTGACAACTTTCCAAACTGAAATTCAAGAAACGGAT
CCACAATCAAGAAACTGCTCTCCTAATTTCAGTGTGAAAACCAATGAAGA
AAGTTTAGATTCGCTGAAGACAGATTCACTAAGCACAAATCCAAACAGAA
ATTCCCAAAAGAGGTCATTACAACTTTGGCAGTTTTTGAAATCCCTTCTA
GATAATCACAAAAATATTCACATTATCACTTGGACAGGGAAAAGTTTGGA
GTTTAAATTAATAGATCCAGAAGAAGTAGCCAAGTTATGGGGACTTCAGA
AAAATCGGCCAGCCATGAATTATGACAAACTAAGTCGTTCACTTCGTTAC
TATTATGAAAAGGGCATCATGCAAAAAGTTGCTGGGGAACGATACATGTA
TAAATTCATTTGTGACCCTTCGGTTTTACTTCAAAACAATTGCAAGCTAA
AAGAATTGGATAACTACAACAAATCTCTCTCATTATCAAGTGACATTGAA
TACAAATCTCAGGTCCACTCAAGTTCCAGAAAGAAATCTCAGAAAATCCC
AAATCCCAACATAAAAAAAAGATCTCAGTTACCAAAAAAGAATTCCAAAT
TGTTGAATTTACAGAAATATCAAAATTCCGTGTCGGATTCATTGGAAATG
CTAAAGAAATCAGATGAATTCCTACAATTCCCATTAAGTATCGAACAAAC
AAAATACAATTCCCCGAATGTAAATTATAAACCTTATCCACATTTCAGGT
TTCCCGAATCAGAAACTGTCAATTCTTCATCGAATAATCCTAATCAAAGT
GATCATCGAGATTTCTCTTCGTCTTTAGATTCATTTAAAAAATATTGCTC
CAACAATTGTACGCCAACATCACAAACCAGTGACTTCACCATGCCATCAT
ATGGTGTTTATGAGCACCTTCTTCCAGGCGGGATTCCAAATATCAGTCCT
CCATATAGCATTATCCCGACTCCCTCCATCCAGGATTGCAACTATGTGCC
ACAGCTGTCAAATTATCAAATCTGGGATCAACATTATCCAAATAAATTCC
AAAATTCTCAAGTTAATCAATACTGGCTAAGAAATTATTGTGACTTTTGA
TTAATCAATTATTACACAAAAATTGATTTTAGTATTTCATGAGTGAAGCT
TCGGAAATTTGTCCGATGAAATATATTTAGAATTGTG

protein sequence of SMED30017161-orf-1

>SMED30017161-orf-1 ID=SMED30017161-orf-1|Name=SMED30017161-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=459bp
MSVGDVNFIWHGINKSTEVDLTCHHGYCVCDESGNNSNNNSTIITNVTQS
NPGEYISERKSTKIYERENEQIHQNFNSINILQSYDHANNNHSQSEILTT
FQTEIQETDPQSRNCSPNFSVKTNEESLDSLKTDSLSTNPNRNSQKRSLQ
LWQFLKSLLDNHKNIHIITWTGKSLEFKLIDPEEVAKLWGLQKNRPAMNY
DKLSRSLRYYYEKGIMQKVAGERYMYKFICDPSVLLQNNCKLKELDNYNK
SLSLSSDIEYKSQVHSSSRKKSQKIPNPNIKKRSQLPKKNSKLLNLQKYQ
NSVSDSLEMLKKSDEFLQFPLSIEQTKYNSPNVNYKPYPHFRFPESETVN
SSSNNPNQSDHRDFSSSLDSFKKYCSNNCTPTSQTSDFTMPSYGVYEHLL
PGGIPNISPPYSIIPTPSIQDCNYVPQLSNYQIWDQHYPNKFQNSQVNQY
WLRNYCDF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0003116	parenchymal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036388	WH-like_DNA-bd_sf
IPR036390	WH_DNA-bd_sf
IPR000418	Ets_dom
IPR011991	WHTH_DNA-bd_dom

Vocabulary: **molecular function**
Term	Definition
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0003677	DNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000418	Ets domain	PRINTS	PR00454	ETSDOMAIN	coord: 192..210 score: 68.72 coord: 173..191 score: 48.88 coord: 211..229 score: 48.25 coord: 149..162 score: 50.0
IPR000418	Ets domain	SMART	SM00413	etsneu2	coord: 148..233 e-value: 3.6E-51 score: 186.0
IPR000418	Ets domain	PFAM	PF00178	Ets	coord: 150..229 e-value: 4.7E-35 score: 119.9
IPR000418	Ets domain	PROSITE	PS00346	ETS_DOMAIN_2	coord: 195..210
IPR000418	Ets domain	PROSITE	PS00345	ETS_DOMAIN_1	coord: 151..159
IPR000418	Ets domain	PROSITE	PS50061	ETS_DOMAIN_3	coord: 149..229 score: 36.989
IPR036388	Winged helix-like DNA-binding domain superfamily	GENE3D	G3DSA:1.10.10.10		coord: 111..248 e-value: 1.5E-45 score: 156.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 263..292
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 269..292
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 123..142
None	No IPR available	PANTHER	PTHR11849:SF282	ETV5-RELATED PROTEIN ETS96B	coord: 50..264
None	No IPR available	PANTHER	PTHR11849	ETS	coord: 50..264
IPR036390	Winged helix DNA-binding domain superfamily	SUPERFAMILY	SSF46785	"Winged helix" DNA-binding domain	coord: 147..266

Main menu

ETS domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

blazegraph-runner