FHA domain-containing protein

Overview
NameFHA domain-containing protein
Smed IDSMED30017080
Length (bp)1608
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of FHA domain-containing protein (SMED30017080) t-SNE clustered cells

Violin plots show distribution of expression levels for FHA domain-containing protein (SMED30017080) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of FHA domain-containing protein (SMED30017080) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for FHA domain-containing protein (SMED30017080) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30017080

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30017080h1SMcG0010905 SmedASXL_014245SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30017080h1SMcG0010905 dd_Smed_v4_11335_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30017080h1SMcG0010905 dd_Smed_v4_11335_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30017080h1SMcG0010905 dd_Smed_v4_11335_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30017080h1SMcG0010905 dd_Smed_v6_11335_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30017080h1SMcG0010905 dd_Smed_v4_11335_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of FHA domain-containing protein vs. TrEMBL
Match: A0A1I8J7B2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 249.98 bits (637), Expect = 5.123e-73
Identity = 168/491 (34.22%), Postives = 250/491 (50.92%), Query Frame = 1 
Query:   85 MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVDKAKPTIGEIIVPNKYDVYKPNDIH--VRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTSGDFLPVHKCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGVDNALRAR-GVGSELLAHDSHYGNCYDDSALPY--RCVSEAAGENCRSQTFGGDMARCMGHSSGDSARNERP--HDRIKSDEAKEYLERSRSGTMNLSVDGTAVTMKP-------KVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLRLYGNAFEIADKNRAKDFFKTIQQQPPS 1515
            M L  ++K  A  NYLKNRG PGQWFQHKADY E +P PR+R    E+  K KPT+GE+   + Y +  P+D    VRL   +A++IAD+FN Q+DKWFDF GN +++P   P KVY  +  E+ +   Q +  DWF HN+ K      P  KC  ++A     R   S AD     W + D +  +     P +R + EG + A R R G G++ +       +  +D    Y  RC + ++  N  + + G  M  C  +S G S   E P    ++K D A+E  +R+  G + +S    +   +        K RPEAEE+  +A+G +    +Q  N+ YSSP+  PR+R   A++A E N+GVM + +G T YRAP        R +    A+E+  K  G + K+L+ +  LPP+   K +     +EE   R   +   ++      ++    P R+   A E A K R  DFFKT+Q +PPS
Sbjct:    1 MALVESSKDQAQSNYLKNRGNPGQWFQHKADYREPQPAPRVRPEAQEIAQKNKPTVGEVF--HNYRL-PPDDAPAPVRLRDEDARRIADKFNNQEDKWFDFHGNYAFRPKPRPVKVYPPSNVELMQRANQAREGDWFDHNK-KPDPQAAPGPKCT-SEAGREIARSMRSQAD-----WYRHDARPTTAPSTRPSSRTRGEGAEYAERNRHGTGTDWMTRKV---DPAEDGVAVYGHRCPTSSSLANYEASSKGSQMRDCFDYSRGAS-HQEPPVAAAKVKGDLAQEVYQRNTRGHIGVSSSAASAAEQAADARVVRKTRPEAEEFANRAKGQMSQWFNQEQNRQYSSPRPQPRVRPGPAQEAAERNRGVMDSCLGDTDYRAPPKDHKTHERALKSDVAKELAAKGRGDAAKSLLGSSNLPPEPPRKSKATPGLAEEHAARNRGTASLVITGAAAPSSARAGP-RVRPEAAETAQKYRGGDFFKTMQMKPPS 476
[Close]
BLAST of FHA domain-containing protein vs. TrEMBL
Match: A0A1I8GEM9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007728g1 PE=4 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 1.607e-72
Identity = 167/491 (34.01%), Postives = 249/491 (50.71%), Query Frame = 1 
Query:   85 MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVDKAKPTIGEIIVPNKYDVYKPNDIH--VRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTSGDFLPVHKCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGVDNALRAR-GVGSELLAHDSHYGNCYDDSALPY--RCVSEAAGENCRSQTFGGDMARCMGHSSGDSARNERP--HDRIKSDEAKEYLERSRSGTMNLSVDGTAVTMKP-------KVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLRLYGNAFEIADKNRAKDFFKTIQQQPPS 1515
            M L  ++K  A  NYLKNRG PGQWFQHKADY E +P PR+R    E+  K KPT+GE+   + Y +  P+D    VRL   +A++IAD+FN Q+DKWFDF GN +++P   P KVY  +  E+ +   Q +  DWF HN+ K      P  KC  ++A     R   S AD     W + D +  +     P +R + EG + A R R G G++ +       +  +D    Y  RC + ++  N  + + G  M  C  +S G S   E P    ++K D A+E  +R+  G + +S    +   +        K RPEAEE+  +A+G +    +Q  N+ YSSP+  PR+R   A++A E N+GVM + +G T YRAP        R +    A+E+  K  G + K L+ +  +PP+   K +     +EE   R   +   ++      ++    P R+   A E A K R  DFFKT+Q +PPS
Sbjct:    1 MALVESSKDQAQSNYLKNRGNPGQWFQHKADYREPQPAPRVRPEAQEIAQKNKPTVGEVF--HNYRL-PPDDAPAPVRLRDEDARRIADKFNNQEDKWFDFHGNYAFRPKPRPVKVYPPSNVELMQRANQAREGDWFDHNK-KPDPQAAPGPKCT-SEAGREIARSMRSQAD-----WYRHDARPTTAPSTRPSSRTRGEGAEYAERNRHGTGTDWMTRKV---DPAEDGVAVYGHRCPTSSSLANYEASSKGSQMRDCFDYSRGAS-HQEPPVAAAKVKGDLAQEVYQRNTRGHIGVSSSAASAAEQAADARVVRKTRPEAEEFANRAKGQMSQWFNQEQNRQYSSPRPQPRVRPGPAQEAAERNRGVMDSCLGDTDYRAPPKDHKTHERALKSDVAKELAAKGRGDAAKALLGSSNMPPEPPRKSKATSGLAEEHAARNRGTASLVITGAAAPSSARAGP-RVRPEAAETAQKYRGGDFFKTMQMKPPS 476
[Close]
BLAST of FHA domain-containing protein vs. TrEMBL
Match: A0A267GZQ6 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007728g3 PE=4 SV=1)

HSP 1 Score: 248.825 bits (634), Expect = 1.830e-72
Identity = 168/491 (34.22%), Postives = 250/491 (50.92%), Query Frame = 1 
Query:   85 MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVDKAKPTIGEIIVPNKYDVYKPNDIH--VRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTSGDFLPVHKCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGVDNALRAR-GVGSELLAHDSHYGNCYDDSALPY--RCVSEAAGENCRSQTFGGDMARCMGHSSGDSARNERP--HDRIKSDEAKEYLERSRSGTMNLSVDGTAVTMKP-------KVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLRLYGNAFEIADKNRAKDFFKTIQQQPPS 1515
            M L  ++K  A  NYLKNRG PGQWFQHKADY E +P PR+R    E+  K KPT+GE+   + Y +  P+D    VRL   +A++IAD+FN Q+DKWFDF GN +++P   P KVY  +  E+ +   Q +  DWF HN+ K      P  KC  ++A     R   S AD     W + D +  +     P +R + EG + A R R G G++ +       +  +D    Y  RC + ++  N  + + G  M  C  +S G S   E P    ++K D A+E  +R+  G + +S    +   +        K RPEAEE+  +A+G +    +Q  N+ YSSP+  PR+R   A++A E N+GVM + +G T YRAP        R +    A+E+  K  G + K+L+ +  LPP+   K +     +EE   R   +   ++      ++    P R+   A E A K R  DFFKT+Q +PPS
Sbjct:   20 MALVESSKDQAQSNYLKNRGNPGQWFQHKADYREPQPAPRVRPEAQEIAQKNKPTVGEVF--HNYRL-PPDDAPAPVRLRDEDARRIADKFNNQEDKWFDFHGNYAFRPKPRPVKVYPPSNVELMQRANQAREGDWFDHNK-KPDPQAAPGPKCT-SEAGREIARSMRSQAD-----WYRHDARPTTAPSTRPSSRTRGEGAEYAERNRHGTGTDWMTRKV---DPAEDGVAVYGHRCPTSSSLANYEASSKGSQMRDCFDYSRGAS-HQEPPVAAAKVKGDLAQEVYQRNTRGHIGVSSSAASAAEQAADARVVRKTRPEAEEFANRAKGQMSQWFNQEQNRQYSSPRPQPRVRPGPAQEAAERNRGVMDSCLGDTDYRAPPKDHKTHERALKSDVAKELAAKGRGDAAKSLLGSSNLPPEPPRKSKATPGLAEEHAARNRGTASLVITGAAAPSSARAGP-RVRPEAAETAQKYRGGDFFKTMQMKPPS 495
[Close]
BLAST of FHA domain-containing protein vs. TrEMBL
Match: A0A1I8FY33 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 1.882e-49
Identity = 138/439 (31.44%), Postives = 215/439 (48.97%), Query Frame = 1 
Query:  241 KPTIGEIIVPNKYDVYKPNDIH--VRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTSGDFLPVHKCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGVDNALRAR-GVGSELLAHDSHYGNCYDDSALPY--RCVSEAAGENCRSQTFGGDMARCMGHSSGDSARNERP--HDRIKSDEAKEYLERSRSGTMNLSVDGTAVTMKP-------KVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLRLYGNAFEIADKNRAKDFFKTIQQQPPS 1515
            KPT+GE+   + Y +  P+D    VRL   +A++IAD+FN Q+DKWFDF GN +++P   P KVY  +  E+ +   Q +  DWF HN+ K      P  KC  ++A     R   S AD     W + D +  +     P +R + EG + A R R G G++ +       +  +D    Y  RC + ++  N  + + G  M  C  +S G S   E P    ++K D A+E  +R+  G + +S    +   +        K RPEAEE+  +A+G +    +Q  N+ YSSP+  PR+R   A++A E N+GVM + +G T YRAP        R +    A+E+  K  G + K L+ +  +PP+   K +     +EE   R   +   ++      ++    P R+   A E A K R  DFFKT+Q +PPS
Sbjct:    2 KPTVGEVF--HNYRL-PPDDAPAPVRLRDEDARRIADKFNNQEDKWFDFHGNYAFRPKPRPVKVYPPSNVELMQRANQAREGDWFDHNK-KPDPQAAPGPKCT-SEAGREIARSMRSQAD-----WYRHDARPTTAPSTRPSSRTRGEGAEYAERNRHGTGTDWMTRKV---DPAEDGVAVYGHRCPTSSSLANYEASSKGSQMRDCFDYSRGAS-HQEPPVAAAKVKGDLAQEVYQRNTRGHIGVSSSAASAAEQAADARVVRKTRPEAEEFANRAKGQMSQWFNQEQNRQYSSPRPQPRVRPGPAQEAAERNRGVMDSCLGDTDYRAPPKDHKTHERALKSDVAKELAAKGRGDAAKALLGSSNMPPEPPRKSKATSGLAEEHAARNRGTASLVITGAAAPSSARAGP-RVRPEAAETAQKYRGGDFFKTMQMKPPS 425
[Close]
BLAST of FHA domain-containing protein vs. TrEMBL
Match: A0A4Z2DGF1 (Uncharacterized protein OS=Schistosoma japonicum OX=6182 GN=EWB00_001171 PE=4 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 1.778e-37
Identity = 149/522 (28.54%), Postives = 236/522 (45.21%), Query Frame = 1 
Query:   85 MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVDKAKP--TIGEII-----VPNKYDVYKPNDI------HVRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYT-KTAEEIAENNWQQKSHDWFSHNRPKTSGDFLPVHKCVGTDALSNSIRIRSSHADEWFK-TWNKKDVKKISTAPNSPKNRVKFEGVDNALRARGVGSELLAHDSHYGNCYDDSALPYRCVSEAAGENCRSQTFGGDMARCMGHS------SGDSARNERPHD-RIKSDEAKEYLERSRSGTMNLSVD-GT----AVTMKPKVRPEAEEYYLKARGNVGSII--------------DQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPV-YKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVS--GSEEGGLRRTSSIGNLLNNYGKKTAPVV-----PPLRLYGNAFEIADKNRAKDFFKTIQQ 1503
            M +T+T    A+ N +KN G PG WF H  DY E  P PR+R+   E+ D+ +   T  EI        N    +  ++I       +RL ++EA+ IA +   Q DKW+DFA NL+Y+P   P ++ T + A+ I +N    +  DWF H        F         D   +S   R +  + WF  +  KK   +I+T  + P +RVK+EGV+ A+R RG+  +LL         +D   +PY C +E A  N +    G +MA C+G            +   RP    ++  +A+ + +  R+G +N S+  GT    +  +  +VRP+ E    K+    GS I                ++  GY       R+RS+EA +A + N+G M++ +G  +Y     Y S    R + GS+AQE    + G ++K LI + +LPP         VS    E   L RT  I  LL        P+V        R+   A E A++++ ++    + Q
Sbjct:    1 MLMTDTFTA-AHENLIKNHGTPGLWFTHTTDYCETLPKPRVRLNAIEIADRNRKHLTTAEISGFVNDCSNSRSNFSTDEINLEQKPQLRLRTSEAQGIAQKSKSQSDKWYDFAENLNYQPTVKPPRIGTGELAKAILKN--MTRESDWFKHKA------FCQSDVEATPDRKLSSGYNRRNEVNNWFAHSPIKKSSSEITTYSSVP-SRVKYEGVEYAIRNRGL-DDLLTMKMLPNELHD--YIPYGCPTEEAKNNAKWSKKGTEMALCLGKQLQPVDVDNHLSSLIRPRSAAVRGSDAEHWRQLGRNGHINSSMSLGTEEDPSNIVHHRVRPDGESILEKSVS--GSQIISCLTTCDTNDKDDSNNIASGY-------RLRSEEAHEAMKRNQGQMSDHLGSKAYSVTQHYGSKFQVRAVRGSEAQEAALNNKGCALKELITHDRLPPSPIGCGFAHVSPEAQEVANLSRTGMISGLLGGCSASNIPLVGVEAPAHRRVQYEAIEYANRDQGQEMKSILTQ 500
[Close]
BLAST of FHA domain-containing protein vs. Planmine SMEST
Match: SMESG000061238.1 (SMESG000061238.1)

HSP 1 Score: 997.268 bits (2577), Expect = 0.000e+0
Identity = 476/478 (99.58%), Postives = 476/478 (99.58%), Query Frame = 1 
Query:   85 MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVDKAKPTIGEIIVPNKYDVYKPNDIHVRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTSGDFLPVHKCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGVDNALRARGVGSELLAHDSHYGNCYDDSALPYRCVSEAAGENCRSQTFGGDMARCMGHSSGDSARNERPHDRIKSDEAKEYLERSRSGTMNLSVDGTAVTMKPKVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLRLYGNAFEIADKNRAKDFFKTIQQQPPSK 1518
            MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVDKAKPTIGEIIVPNKYDVYKPNDIHVRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTS DFLPVHKCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGVDNALRARGVGSELL HDSHYGNCYDDSALPYRCVSEAAGENCRSQTFGGDMARCMGHSSGDSARNERPHDRIKSDEAKEYLERSRSGTMNLSVDGTAVTMKPKVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLRLYGNAFEIADKNRAKDFFKTIQQQPPSK
Sbjct:    1 MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVDKAKPTIGEIIVPNKYDVYKPNDIHVRLTSAEAKKIADRFNFQDDKWFDFAGNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTSADFLPVHKCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGVDNALRARGVGSELLVHDSHYGNCYDDSALPYRCVSEAAGENCRSQTFGGDMARCMGHSSGDSARNERPHDRIKSDEAKEYLERSRSGTMNLSVDGTAVTMKPKVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYETNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLIENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLRLYGNAFEIADKNRAKDFFKTIQQQPPSK 478
The following BLAST results are available for this feature:
BLAST of FHA domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8J7B25.123e-7334.22Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GEM91.607e-7234.01Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267GZQ61.830e-7234.22Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8FY331.882e-4931.44Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A4Z2DGF11.778e-3728.54Uncharacterized protein OS=Schistosoma japonicum O... [more]
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BLAST of FHA domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FHA domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000061238.10.000e+099.58SMESG000061238.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30017080 ID=SMED30017080|Name=FHA domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1608bp
GTTATTTTCTATTAAAATTTTCATTGAATAACTTTTTAGTTATATTAAAT
TAATATATTATATTTTACCTTATAATTTCCACAAATGTATTTGACGAACA
CAACTAAACAAGATGCCAATTTAAACTACTTAAAGAATCGGGGTGAACCG
GGCCAATGGTTCCAACACAAGGCCGATTACGTTGAAGATAAACCAATTCC
GAGAATACGTGTCGGAGGCTTCGAAGTTGTTGATAAAGCAAAACCAACAA
TTGGGGAAATTATTGTTCCGAATAAATATGATGTCTACAAACCAAACGAT
ATTCATGTCAGGTTAACTTCAGCTGAAGCTAAAAAAATAGCCGATAGATT
CAATTTTCAAGATGATAAATGGTTTGATTTCGCGGGGAATTTATCATATA
AACCACCGAAAGCACCTAAAAAAGTTTATACTAAAACTGCCGAAGAAATC
GCAGAGAATAATTGGCAACAGAAATCCCATGACTGGTTCAGCCACAATCG
ACCCAAAACCTCTGGAGACTTTCTCCCTGTTCATAAATGCGTCGGAACGG
ATGCGTTGTCCAATAGTATTAGAATTAGATCTAGTCATGCAGATGAATGG
TTTAAAACTTGGAATAAAAAAGATGTAAAAAAAATATCTACTGCCCCAAA
TAGCCCTAAAAACCGTGTGAAATTTGAAGGCGTTGACAATGCATTGCGTG
CACGAGGTGTTGGATCCGAGCTATTAGCGCATGATAGCCATTATGGAAAC
TGCTACGACGATTCAGCTTTGCCGTATCGTTGTGTTAGTGAAGCAGCAGG
AGAGAACTGCCGCAGTCAGACGTTTGGTGGTGACATGGCAAGATGCATGG
GCCATTCATCTGGAGACTCGGCTCGCAATGAAAGACCACACGATAGAATA
AAAAGTGATGAAGCTAAAGAATATCTAGAAAGAAGCAGAAGCGGTACAAT
GAATCTCTCTGTCGATGGAACGGCTGTAACTATGAAACCAAAAGTAAGAC
CGGAAGCGGAAGAATATTATTTGAAAGCTAGGGGAAATGTTGGATCAATC
ATAGATCAAAGCGTAAATAAAGGTTATTCATCTCCTCAACAAGTTCCGCG
AATAAGAAGTGACGAGGCTCGACAAGCTTACGAGACTAATAAAGGAGTTA
TGGCAAATGTTGTTGGTAAAACTAGTTATCGCGCTCCGGTCTATAAATCA
AACCATTTGGCCCGAGGTATTATTGGTTCAGATGCTCAGGAAGTTATGCA
TAAACATATTGGAAGCTCAATGAAAACTCTAATTGAAAATTATAAATTGC
CACCGGATGCGCAACCAAAACAAAGAGTCGGTGTTTCAGGTTCGGAAGAA
GGAGGCTTGAGACGAACTTCTTCGATAGGAAATTTATTGAATAACTACGG
AAAGAAAACCGCTCCAGTTGTTCCACCTTTAAGATTATATGGAAATGCAT
TTGAAATAGCAGATAAAAACAGAGCCAAGGATTTTTTCAAAACAATCCAG
CAACAGCCTCCAAGCAAATAATAAATTTACATATTTTATTTGAATCACAT
CTACATGGAATCTATGTATCTGAAGCGGCATTTTATAAAATACTGGTCTT
GTTTTAAA
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protein sequence of SMED30017080-orf-1

>SMED30017080-orf-1 ID=SMED30017080-orf-1|Name=SMED30017080-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=479bp
MYLTNTTKQDANLNYLKNRGEPGQWFQHKADYVEDKPIPRIRVGGFEVVD
KAKPTIGEIIVPNKYDVYKPNDIHVRLTSAEAKKIADRFNFQDDKWFDFA
GNLSYKPPKAPKKVYTKTAEEIAENNWQQKSHDWFSHNRPKTSGDFLPVH
KCVGTDALSNSIRIRSSHADEWFKTWNKKDVKKISTAPNSPKNRVKFEGV
DNALRARGVGSELLAHDSHYGNCYDDSALPYRCVSEAAGENCRSQTFGGD
MARCMGHSSGDSARNERPHDRIKSDEAKEYLERSRSGTMNLSVDGTAVTM
KPKVRPEAEEYYLKARGNVGSIIDQSVNKGYSSPQQVPRIRSDEARQAYE
TNKGVMANVVGKTSYRAPVYKSNHLARGIIGSDAQEVMHKHIGSSMKTLI
ENYKLPPDAQPKQRVGVSGSEEGGLRRTSSIGNLLNNYGKKTAPVVPPLR
LYGNAFEIADKNRAKDFFKTIQQQPPSK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head