Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017052 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 500.36 bits (1287), Expect = 4.383e-169 Identity = 241/356 (67.70%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + RVALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E +E ++FDL+ MLEYEPA R++LG AL HPFF RL PP++ SSR IS
Sbjct: 143 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWD--SSRDIS 496
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 500.36 bits (1287), Expect = 4.383e-169 Identity = 241/356 (67.70%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + RVALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E +E ++FDL+ MLEYEPA R++LG AL HPFF RL PP++ SSR IS
Sbjct: 143 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWD--SSRDIS 496
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 499.975 bits (1286), Expect = 5.568e-169 Identity = 241/356 (67.70%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + RVALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E +E ++FDL+ MLEYEPA R++LG AL HPFF RL PP++ SSR IS
Sbjct: 144 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWD--SSRDIS 497
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 499.975 bits (1286), Expect = 5.568e-169 Identity = 241/356 (67.70%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + RVALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E +E ++FDL+ MLEYEPA R++LG AL HPFF RL PP++ SSR IS
Sbjct: 144 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWD--SSRDIS 497
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 499.975 bits (1286), Expect = 5.762e-169 Identity = 241/356 (67.70%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + RVALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E +E ++FDL+ MLEYEPA R++LG AL HPFF RL PP++ SSR IS
Sbjct: 145 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWD--SSRDIS 498
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 437.573 bits (1124), Expect = 7.778e-144 Identity = 208/338 (61.54%), Postives = 253/338 (74.85%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLP 2314
DDK+GHLIY GD I+ R+ I TLGEGTFGKVV V++ S +ALKIIKNV KYREAA LE+ VL+ + EKDPE K I M ++FD+ GH+C+ F+L G S+FDFLK N Y PYPME HI++QLC AVKFLHD LTHTDLKPENILFV DS K+ RV+ ++ +RLIDFGSATFDHEHHS IVSTRHYRAPEVILELGWS+ CDVWSI CI++ELYTG TLFQTH+N+EHLAMMER+LG P RMA+++KT FF +G+LDW S D YVR+NC+PL R + + E +E+F+L+ ML +EP R+ L AL H +F RLP
Sbjct: 239 DDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVR-VNDSLSDTFMALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFV--DSRYTTKLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTKTKFFINGRLDWVNTSADAAYVRDNCKPLRRSMSCTDPEHVELFELIENMLMFEPLARMKLPEALQHRYFNRLP 573
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 442.195 bits (1136), Expect = 5.705e-142 Identity = 209/340 (61.47%), Postives = 256/340 (75.29%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNS--DSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLP 2314
DDK+GHLIY GD I+ R+ I TLGEGTFGKVV V++ S +ALKIIKNV KYREAA LE+ VL+ + EKDPE K I M ++FD+ GH+C+ F+L G S+FDFLK N Y PYPME HI++QLC AVKFLHD LTHTDLKPENILFV+S + LV K+ RV+ ++ +RLIDFGSATFDHEHHS IVSTRHYRAPEVILELGWS+ CDVWSI CI++ELYTG TLFQTH+N+EHLAMMER+LG P RMA+++KT FF +G+LDW S D YVR+NC+PL R + + E +E+F+L+ ML +EP R+ L AL H +F RLP
Sbjct: 533 DDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVR-VNDSLSDTFMALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTTKLV----DKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTKTKFFINGRLDWVNTSADAAYVRDNCKPLRRSMSCTDPEHVELFELIENMLMFEPLARMKLPEALQHRYFNRLP 867
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 431.409 bits (1108), Expect = 2.518e-141 Identity = 207/341 (60.70%), Postives = 253/341 (74.19%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS---KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLP 2314
DDK+GHLIY GD I+ R+ I TLGEGTFGKVV V++ S +ALKIIKNV KYREAA LE+ VL+ + EKDPE K I M ++FD+ GH+C+ F+L G S+FDFLK N Y PYPME HI++QLC AVKFLHD LTHTDLKPENILFV DS K+ RV+ ++ +RLIDFGSATFDHEHHS IVSTRHYRAPEVILELGWS+ CDVWSI CI++ELYTG TLFQTH+N+EHLAMMER+LG P RMA+++ +T FF +G+LDW S D YVR+NC+PL R + + E +E+F+L+ ML +EP R+ L AL H +F RLP
Sbjct: 239 DDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVR-VNDSLSDTFMALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFV--DSRYTTKLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTNTFRTKFFINGRLDWVNTSADAAYVRDNCKPLRRSMSCTDPEHVELFELIENMLMFEPLARMKLPEALQHRYFNRLP 576
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 436.032 bits (1120), Expect = 1.622e-139 Identity = 208/343 (60.64%), Postives = 256/343 (74.64%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNS--DSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS---KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLP 2314
DDK+GHLIY GD I+ R+ I TLGEGTFGKVV V++ S +ALKIIKNV KYREAA LE+ VL+ + EKDPE K I M ++FD+ GH+C+ F+L G S+FDFLK N Y PYPME HI++QLC AVKFLHD LTHTDLKPENILFV+S + LV K+ RV+ ++ +RLIDFGSATFDHEHHS IVSTRHYRAPEVILELGWS+ CDVWSI CI++ELYTG TLFQTH+N+EHLAMMER+LG P RMA+++ +T FF +G+LDW S D YVR+NC+PL R + + E +E+F+L+ ML +EP R+ L AL H +F RLP
Sbjct: 533 DDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVR-VNDSLSDTFMALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTTKLV----DKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTNTFRTKFFINGRLDWVNTSADAAYVRDNCKPLRRSMSCTDPEHVELFELIENMLMFEPLARMKLPEALQHRYFNRLP 870
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 331.643 bits (849), Expect = 1.480e-107 Identity = 157/254 (61.81%), Postives = 193/254 (75.98%), Query Frame = 2
Query: 1553 MLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLP 2314
M ++FD+ GH+C+ F+L G S+FDFLK N Y PYPME HI++QLC AVKFLHD LTHTDLKPENILFV DS K+ RV+ ++ +RLIDFGSATFDHEHHS IVSTRHYRAPEVILELGWS+ CDVWSI CI++ELYTG TLFQTH+N+EHLAMMER+LG P RMA+++KT FF +G+LDW S D YVR+NC+PL R + + E +E+F+L+ ML +EP R+ L AL H +F RLP
Sbjct: 1 MGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFV--DSRYTTKLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTKTKFFINGRLDWVNTSADAAYVRDNCKPLRRSMSCTDPEHVELFELIENMLMFEPLARMKLPEALQHRYFNRLP 252
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299748) HSP 1 Score: 498.049 bits (1281), Expect = 2.575e-168 Identity = 231/350 (66.00%), Postives = 284/350 (81.14%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRR 2350
DD +GHLIY GD++ RY+I+ TLGEGTFG+VV+ D ++ +ALKIIKNVEKYREAA LEIN L+ I +KDP +L +KM++WFD++GHMCI FE+ G SVFDFL+EN+Y PYP++ VRH++YQLC++VKFLHD LTHTDLKPENILFV+SD N K R+ R VKN+++RLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CI+FELY G TLFQTHDN+EHLAMMERILG PYRMARK+KT +FYHGKLDWD S GRYVR++C+PL ++++ E+F L+ KMLEYEP+ RI+LG AL HPFF RLPPH R+ +S+++
Sbjct: 146 DDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYC-MALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQ 494
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299752) HSP 1 Score: 498.049 bits (1281), Expect = 2.575e-168 Identity = 231/350 (66.00%), Postives = 284/350 (81.14%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRR 2350
DD +GHLIY GD++ RY+I+ TLGEGTFG+VV+ D ++ +ALKIIKNVEKYREAA LEIN L+ I +KDP +L +KM++WFD++GHMCI FE+ G SVFDFL+EN+Y PYP++ VRH++YQLC++VKFLHD LTHTDLKPENILFV+SD N K R+ R VKN+++RLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CI+FELY G TLFQTHDN+EHLAMMERILG PYRMARK+KT +FYHGKLDWD S GRYVR++C+PL ++++ E+F L+ KMLEYEP+ RI+LG AL HPFF RLPPH R+ +S+++
Sbjct: 146 DDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYC-MALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQ 494
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299745) HSP 1 Score: 499.975 bits (1286), Expect = 5.114e-168 Identity = 231/350 (66.00%), Postives = 284/350 (81.14%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRR 2350
DD +GHLIY GD++ RY+I+ TLGEGTFG+VV+ D ++ +ALKIIKNVEKYREAA LEIN L+ I +KDP +L +KM++WFD++GHMCI FE+ G SVFDFL+EN+Y PYP++ VRH++YQLC++VKFLHD LTHTDLKPENILFV+SD N K R+ R VKN+++RLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CI+FELY G TLFQTHDN+EHLAMMERILG PYRMARK+KT +FYHGKLDWD S GRYVR++C+PL ++++ E+F L+ KMLEYEP+ RI+LG AL HPFF RLPPH R+ +S+++
Sbjct: 215 DDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYC-MALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQ 563
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299742) HSP 1 Score: 499.975 bits (1286), Expect = 5.114e-168 Identity = 231/350 (66.00%), Postives = 284/350 (81.14%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRR 2350
DD +GHLIY GD++ RY+I+ TLGEGTFG+VV+ D ++ +ALKIIKNVEKYREAA LEIN L+ I +KDP +L +KM++WFD++GHMCI FE+ G SVFDFL+EN+Y PYP++ VRH++YQLC++VKFLHD LTHTDLKPENILFV+SD N K R+ R VKN+++RLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CI+FELY G TLFQTHDN+EHLAMMERILG PYRMARK+KT +FYHGKLDWD S GRYVR++C+PL ++++ E+F L+ KMLEYEP+ RI+LG AL HPFF RLPPH R+ +S+++
Sbjct: 215 DDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYC-MALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQ 563
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299750) HSP 1 Score: 499.975 bits (1286), Expect = 5.114e-168 Identity = 231/350 (66.00%), Postives = 284/350 (81.14%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRR 2350
DD +GHLIY GD++ RY+I+ TLGEGTFG+VV+ D ++ +ALKIIKNVEKYREAA LEIN L+ I +KDP +L +KM++WFD++GHMCI FE+ G SVFDFL+EN+Y PYP++ VRH++YQLC++VKFLHD LTHTDLKPENILFV+SD N K R+ R VKN+++RLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CI+FELY G TLFQTHDN+EHLAMMERILG PYRMARK+KT +FYHGKLDWD S GRYVR++C+PL ++++ E+F L+ KMLEYEP+ RI+LG AL HPFF RLPPH R+ +S+++
Sbjct: 215 DDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYC-MALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQ 563
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk2b (CDC-like kinase 2b [Source:ZFIN;Acc:ZDB-GENE-060929-1126]) HSP 1 Score: 483.797 bits (1244), Expect = 8.684e-163 Identity = 222/335 (66.27%), Postives = 274/335 (81.79%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLIY GD++ RY I +TLGEGTFGKVVECVD+ + R+ALKIIKNVEKY+EAA LEINVL+ I ++DPE+K L ++ML+WFD++GHMC+SFEL G S FDF+KEN+Y PY + VRH++YQ+C AVKFLHD LTHTDLKPENILFV+SD ++ N+++KRD+R V ++ +R++DFGSATFDHEHHS+IVSTRHYRAPEVILELGWS+ CDVWSI CI+FE Y GYTL+QTHDN+EHLAMMERI G P RM RK+ K +FY G+LDWD + GRYVRENCRPL RY E+++ + FDL+ +LEYEP R+SL AAL HPFF
Sbjct: 147 DDEEGHLIYRAGDVLQDRYEITQTLGEGTFGKVVECVDHQRGGSRIALKIIKNVEKYKEAARLEINVLEKINQRDPENKNLCVQMLDWFDYHGHMCLSFELLGLSTFDFMKENNYLPYSISQVRHMAYQICLAVKFLHDNKLTHTDLKPENILFVSSDYSVLYNAEKKRDERSVNSTAVRIVDFGSATFDHEHHSSIVSTRHYRAPEVILELGWSQPCDVWSIGCILFEFYCGYTLYQTHDNREHLAMMERIHGPVPSRMIRKTRKQKYFYRGRLDWDESTSAGRYVRENCRPLRRYMLCESEDHHQFFDLLEGLLEYEPEQRLSLSAALRHPFF 481
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk2a (CDC-like kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-298]) HSP 1 Score: 483.797 bits (1244), Expect = 2.066e-162 Identity = 223/335 (66.57%), Postives = 269/335 (80.30%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLI GD++ RY IV TLGEGTFG+V++C+D+ + VALKIIKNVEKY+EAA LEINVL+ I EKDPE+ L ++M +WFD++GHMCISFEL S FDFLKEN+Y PY + VRH++YQ+C AVKFLH+ LTHTDLKPENILFVNSD + N ++KRD+R VKN+ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI I+FE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD S GRYVRENC+PL RY E +E ++FDL+ MLEYEP+ R++L AAL HPFF
Sbjct: 170 DDEEGHLICRSGDVLQERYEIVSTLGEGTFGRVMQCIDHRRGGAHVALKIIKNVEKYKEAARLEINVLERINEKDPENNNLCVQMFDWFDYHGHMCISFELLALSTFDFLKENNYLPYSINQVRHMAYQVCLAVKFLHENKLTHTDLKPENILFVNSDYTVTYNVEKKRDERTVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGSILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKPLRRYLLSEAEEHHQLFDLIEAMLEYEPSKRLTLAAALRHPFF 504
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk2a (CDC-like kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-298]) HSP 1 Score: 483.797 bits (1244), Expect = 2.178e-162 Identity = 223/335 (66.57%), Postives = 269/335 (80.30%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLI GD++ RY IV TLGEGTFG+V++C+D+ + VALKIIKNVEKY+EAA LEINVL+ I EKDPE+ L ++M +WFD++GHMCISFEL S FDFLKEN+Y PY + VRH++YQ+C AVKFLH+ LTHTDLKPENILFVNSD + N ++KRD+R VKN+ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI I+FE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD S GRYVRENC+PL RY E +E ++FDL+ MLEYEP+ R++L AAL HPFF
Sbjct: 169 DDEEGHLICRSGDVLQERYEIVSTLGEGTFGRVMQCIDHRRGGAHVALKIIKNVEKYKEAARLEINVLERINEKDPENNNLCVQMFDWFDYHGHMCISFELLALSTFDFLKENNYLPYSINQVRHMAYQVCLAVKFLHENKLTHTDLKPENILFVNSDYTVTYNVEKKRDERTVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGSILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKPLRRYLLSEAEEHHQLFDLIEAMLEYEPSKRLTLAAALRHPFF 503
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk4a (CDC-like kinase 4a [Source:ZFIN;Acc:ZDB-GENE-030131-576]) HSP 1 Score: 434.876 bits (1117), Expect = 8.276e-144 Identity = 194/335 (57.91%), Postives = 261/335 (77.91%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTS-FFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHL+Y GDM+ RY IV TLGEG FGKVVEC+D+++ R+ALKIIKN+E+YR+AAL E+ VL+ I D + +Y ++M +WFDH+GH+CI+FEL G S +DFLKEN++ P+ + H+RH++YQ+ AV+FLH LTHTDLKPENILFVNS+ + NSK KRD+R VKN +++++DFG+AT++HEHH+++VSTRHYRAPEVIL+LGWS SCDVWS+ CI+ E Y G TLFQTHD+KEHLAMMER+LG P M +K++ S F + KLDWD +S GRYVR+ C+PL +Y + + ++FDL+ +MLEY+ RI+L A+ HPFF
Sbjct: 154 DDEEGHLVYHSGDMLRARYEIVCTLGEGAFGKVVECIDHEKVGARIALKIIKNIERYRDAALSEVEVLEQINSLDCDRRYACVRMYDWFDHHGHICIAFELLGLSTYDFLKENNFQPFYINHIRHMAYQIIRAVRFLHKNKLTHTDLKPENILFVNSEYNIRYNSKMKRDERTVKNPDVKVVDFGNATYEHEHHTSVVSTRHYRAPEVILDLGWSHSCDVWSVGCILIEYYLGSTLFQTHDSKEHLAMMERVLGPIPTHMLQKTRKSRFVRNDKLDWDIHSSSGRYVRKQCKPLRQYLVSSSSDHEQLFDLIERMLEYDVTKRITLDEAIKHPFF 488
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk4b (CDC-like kinase 4b [Source:ZFIN;Acc:ZDB-GENE-050227-19]) HSP 1 Score: 424.861 bits (1091), Expect = 2.595e-140 Identity = 190/335 (56.72%), Postives = 262/335 (78.21%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKT-SFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHL+Y +GDM+ RY IV TLGEG FGKVVEC+D+ + + RVALKIIKN+E+YREAAL E++VL+ I D E ++ ++ML+WFDH+GH+CI FEL G S +DFLKEN + P+ + +RH++ Q+ AV+FLH LTHTDLKPENILFV+S+ + NS+ KRD+R +K +++++DFG+AT+DHEHH+++VSTRHYRAPEVILELGW+++CDVWS+ CI+ E Y G TLFQTHD+KEHLAMME++LG P + +K+K + +H KLDWD +S GRYVR++C+PL +Y + + E +FDL+ KM+EY+ + RI+L A+ HPFF
Sbjct: 137 DDEEGHLVYHNGDMLRARYEIVGTLGEGAFGKVVECLDHTKGNVRVALKIIKNIERYREAALSEVDVLERINSLDDEKRFACVRMLDWFDHHGHICIVFELLGLSTYDFLKENGFMPFSLTQIRHMADQIFRAVRFLHKNKLTHTDLKPENILFVDSNYDIKYNSRMKRDERTLKRLDVKVVDFGNATYDHEHHTSVVSTRHYRAPEVILELGWNQACDVWSLGCILVEFYLGLTLFQTHDSKEHLAMMEKVLGPIPTHLLQKTKKRRYVHHDKLDWDEHSSAGRYVRKHCKPLKQYMSSKTPEHELLFDLLQKMMEYDSSKRITLEQAIGHPFF 471
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ezr (ezrin [Source:Xenbase;Acc:XB-GENE-484766]) HSP 1 Score: 437.958 bits (1125), Expect = 5.617e-145 Identity = 204/346 (58.96%), Postives = 267/346 (77.17%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHT 2335
+DKEGHL+ G+ I RY IV LG+GTFGKVVEC+D + + RVALKII+NV KYREAA LEINVL+ I+E+D ++K + + M +WFD +GH+CI+FEL G+S F+F KEN++ PYP+ H+RH+++QLC A+KFLH+ LTHTDLKPENILFVNS+ + N +K +++ VKN IR++DFGSATFDHE+H+TIV+TRHYR PEVILELGWS+ CDVWS+ CI+FE YTG+TLFQTHDN+EHL MME+ILG P RM K+ K +F++G L WD S DGRYV +NC L+ Y + ++ E +++FDL+S+MLE+ PA RI+L AL H FF L P Q T
Sbjct: 139 NDKEGHLVCRTGERIQERYEIVGDLGKGTFGKVVECLDLARGNSRVALKIIRNVRKYREAAQLEINVLEKIKERDQDNKNMCVLMRDWFDFHGHVCIAFELLGKSTFEFQKENNFLPYPLAHIRHMAFQLCQALKFLHENQLTHTDLKPENILFVNSEYDICYNESKKCEEKCVKNPSIRIVDFGSATFDHEYHTTIVATRHYRPPEVILELGWSQPCDVWSLGCILFEYYTGFTLFQTHDNREHLVMMEKILGPLPRRMVYKTRKQKYFHNGSLIWDENSSDGRYVSKNCHQLMSYKSSDSAEHVQLFDLLSRMLEFRPALRITLQEALEHQFFTCLKPQQMTRT 484
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ezr (ezrin [Source:Xenbase;Acc:XB-GENE-484766]) HSP 1 Score: 436.032 bits (1120), Expect = 3.361e-144 Identity = 202/342 (59.06%), Postives = 266/342 (77.78%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQ 2323
+DKEGHL+ G+ I RY IV LG+GTFGKVVEC+D + + RVALKII+NV KYREAA LEINVL+ I+E+D ++K + + M +WFD +GH+CI+FEL G+S F+F KEN++ PYP+ H+RH+++QLC A+KFLH+ LTHTDLKPENILFVNS+ + N +K +++ VKN IR++DFGSATFDHE+H+TIV+TRHYR PEVILELGWS+ CDVWS+ CI+FE YTG+TLFQTHDN+EHL MME+ILG P RM K+ K +F++G L WD S DGRYV +NC L+ Y + ++ E +++FDL+S+MLE+ PA RI+L AL H FF L P +
Sbjct: 144 NDKEGHLVCRTGERIQERYEIVGDLGKGTFGKVVECLDLARGNSRVALKIIRNVRKYREAAQLEINVLEKIKERDQDNKNMCVLMRDWFDFHGHVCIAFELLGKSTFEFQKENNFLPYPLAHIRHMAFQLCQALKFLHENQLTHTDLKPENILFVNSEYDICYNESKKCEEKCVKNPSIRIVDFGSATFDHEYHTTIVATRHYRPPEVILELGWSQPCDVWSLGCILFEYYTGFTLFQTHDNREHLVMMEKILGPLPRRMVYKTRKQKYFHNGSLIWDENSSDGRYVSKNCHQLMSYKSSDSAEHVQLFDLLSRMLEFRPALRITLQEALEHQFFTCLKPEE 485
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dkk3 (dickkopf WNT signaling pathway inhibitor 3 [Source:Xenbase;Acc:XB-GENE-877183]) HSP 1 Score: 426.017 bits (1094), Expect = 4.348e-142 Identity = 194/334 (58.08%), Postives = 261/334 (78.14%), Query Frame = 2
Query: 1304 DKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
D+EGHLI GD++ RY IV LGEG FGKV+EC+D+ + +RVA+KIIKNVE+YREAA EI VL+ + KDP + + ++ML WFDH+GH+CI FEL G S +DF+KENS+ P+P++H+R+++YQ+C ++ FLH LTHTDLKPENILFV+SD ++ N +K+D+R +KNS+I+++DFGSAT++ E+HS +VSTRHYRAPEVILELGWS+ CDVWSI CI+ E Y G T+FQTHD+KEHLAMMERILG P M +K+ K +FY +LDWD +S GRYV++ C+PL Y +N++ ++FDL+ +MLEY+PA RI+L AL HPFF
Sbjct: 40 DEEGHLICESGDVLRERYEIVHALGEGAFGKVLECIDHLRGGERVAVKIIKNVERYREAAQSEIQVLEHLNRKDPINTFRCVQMLEWFDHHGHICIVFELLGLSTYDFIKENSFLPFPLDHIRNMAYQICKSINFLHQNQLTHTDLKPENILFVHSDYVVHFNHAKKQDERYLKNSDIKIVDFGSATYNDEYHSALVSTRHYRAPEVILELGWSQPCDVWSIGCILIEYYLGLTVFQTHDSKEHLAMMERILGPLPLHMIKKTRKHKYFYLDRLDWDEHSSAGRYVKKRCKPLKEYMVSDNKDHHQLFDLIQRMLEYDPAKRITLEEALKHPFF 373
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dkk3 (dickkopf WNT signaling pathway inhibitor 3 [Source:Xenbase;Acc:XB-GENE-877183]) HSP 1 Score: 429.098 bits (1102), Expect = 1.049e-141 Identity = 201/363 (55.37%), Postives = 275/363 (75.76%), Query Frame = 2
Query: 1220 SNRTS-VEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
S+RTS ++ K S+S+++ D+EGHLI GD++ RY IV LGEG FGKV+EC+D+ + +RVA+KIIKNVE+YREAA EI VL+ + KDP + + ++ML WFDH+GH+CI FEL G S +DF+KENS+ P+P++H+R+++YQ+C ++ FLH LTHTDLKPENILFV+SD ++ N +K+D+R +KNS+I+++DFGSAT++ E+HS +VSTRHYRAPEVILELGWS+ CDVWSI CI+ E Y G T+FQTHD+KEHLAMMERILG P M +K+ K +FY +LDWD +S GRYV++ C+PL Y +N++ ++FDL+ +MLEY+PA RI+L AL HPFF
Sbjct: 123 SSRTSHLKSHRKKRSRSVEV---------DEEGHLICESGDVLRERYEIVHALGEGAFGKVLECIDHLRGGERVAVKIIKNVERYREAAQSEIQVLEHLNRKDPINTFRCVQMLEWFDHHGHICIVFELLGLSTYDFIKENSFLPFPLDHIRNMAYQICKSINFLHQNQLTHTDLKPENILFVHSDYVVHFNHAKKQDERYLKNSDIKIVDFGSATYNDEYHSALVSTRHYRAPEVILELGWSQPCDVWSIGCILIEYYLGLTVFQTHDSKEHLAMMERILGPLPLHMIKKTRKHKYFYLDRLDWDEHSSAGRYVKKRCKPLKEYMVSDNKDHHQLFDLIQRMLEYDPAKRITLEEALKHPFF 476
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dkk3 (dickkopf WNT signaling pathway inhibitor 3 [Source:Xenbase;Acc:XB-GENE-877183]) HSP 1 Score: 420.239 bits (1079), Expect = 9.493e-140 Identity = 194/334 (58.08%), Postives = 260/334 (77.84%), Query Frame = 2
Query: 1304 DKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
D+EGHLI GD++ RY IV LGEG FGKV+EC+D+ + +RVA+KIIKNVE+YREAA EI VL+ + KDP + + ++ML WFDH+GH+CI FEL G S +DF+KENS+ P+P++H+R+++YQ+C ++ FLH LTHTDLKPENILFV+SD ++ N K+D+R +KNS+I+++DFGSAT++ E+HS +VSTRHYRAPEVILELGWS+ CDVWSI CI+ E Y G T+FQTHD+KEHLAMMERILG P M +K+ K +FY +LDWD +S GRYV++ C+PL Y +N++ ++FDL+ +MLEY+PA RI+L AL HPFF
Sbjct: 40 DEEGHLICESGDVLRERYEIVHALGEGAFGKVLECIDHLRGGERVAVKIIKNVERYREAAQSEIQVLEHLNRKDPINTFRCVQMLEWFDHHGHICIVFELLGLSTYDFIKENSFLPFPLDHIRNMAYQICKSINFLHQNQLTHTDLKPENILFVHSDYVVHFN--HKQDERYLKNSDIKIVDFGSATYNDEYHSALVSTRHYRAPEVILELGWSQPCDVWSIGCILIEYYLGLTVFQTHDSKEHLAMMERILGPLPLHMIKKTRKHKYFYLDRLDWDEHSSAGRYVKKRCKPLKEYMVSDNKDHHQLFDLIQRMLEYDPAKRITLEEALKHPFF 371
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk2 (CDC-like kinase 2 [Source:MGI Symbol;Acc:MGI:1098669]) HSP 1 Score: 495.738 bits (1275), Expect = 1.825e-167 Identity = 239/356 (67.13%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + +VALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E ++ ++FDL+ MLEYEPA R++LG AL HPFF L PP+ +L SSR IS
Sbjct: 143 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEDHHQLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWD-SSRDIS 497
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk2 (CDC-like kinase 2 [Source:MGI Symbol;Acc:MGI:1098669]) HSP 1 Score: 495.738 bits (1275), Expect = 1.889e-167 Identity = 239/356 (67.13%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + +VALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E ++ ++FDL+ MLEYEPA R++LG AL HPFF L PP+ +L SSR IS
Sbjct: 144 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEDHHQLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWD-SSRDIS 498
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk2 (CDC-like kinase 2 [Source:MGI Symbol;Acc:MGI:1098669]) HSP 1 Score: 495.738 bits (1275), Expect = 1.954e-167 Identity = 239/356 (67.13%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + +VALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E ++ ++FDL+ MLEYEPA R++LG AL HPFF L PP+ +L SSR IS
Sbjct: 145 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEDHHQLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWD-SSRDIS 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk3 (CDC-like kinase 3 [Source:MGI Symbol;Acc:MGI:1098670]) HSP 1 Score: 450.284 bits (1157), Expect = 7.267e-148 Identity = 209/343 (60.93%), Postives = 266/343 (77.55%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRM-ARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQR 2326
DDKEGHL+ GD + RY IV LGEGTFGKVVEC+D+ + +VALKII+NV KYREAA LEINVLK I+EKD E+K+L + M +WF+ +GHMCI+FEL G++ F+FLKEN++ PYP+ HVRH++YQLC A++FLH+ LTHTDLKPENILFVNS+ + N + +++ VKN+ IR+ DFGSATFDHEHH+TIV+TRHYR PEVILELGW++ CDVWSI CI+FE Y G+TLFQTH+N+EHL MME+ILG P M R K +FY G L WD S DGRYV+ENC+PL Y ++ E +++FDL+ +MLE++PA RI+L AL HPFF L P +R
Sbjct: 286 DDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER 628
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk4 (CDC like kinase 4 [Source:MGI Symbol;Acc:MGI:1098551]) HSP 1 Score: 429.483 bits (1103), Expect = 6.274e-142 Identity = 201/337 (59.64%), Postives = 257/337 (76.26%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRY--CTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLI GD++ RY IV TLGEG FGKVVEC+D+ VA+KI+KNV +YREAA EI VL+ + DP S + ++ML WFDH+GH+CI FEL G S +DF+KENS+ P+ ++H+R ++YQ+C ++ FLH LTHTDLKPENILFV SD ++ NSK KRD+R +KN++I+++DFGSAT+D EHHST+VSTRHYRAPEVIL LGWS+ CDVWSI CI+ E Y G+T+FQTHD+KEHLAMMERILG P M +K+ K +F+H +LDWD +S GRYVR C+PL + C DE E ++FDLV +MLEY+PA RI+L AL HPFF
Sbjct: 141 DDEEGHLICQSGDVLRARYEIVDTLGEGAFGKVVECIDHGMDGLHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFELLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYVVKYNSKMKRDERTLKNTDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHMIQKTRKRKYFHHNQLDWDEHSSAGRYVRRRCKPLKEFMLCHDEEHE--KLFDLVRRMLEYDPARRITLDEALQHPFF 475
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P49760|CLK2_HUMAN (Dual specificity protein kinase CLK2 OS=Homo sapiens OX=9606 GN=CLK2 PE=1 SV=1) HSP 1 Score: 499.975 bits (1286), Expect = 2.767e-168 Identity = 241/356 (67.70%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + RVALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E +E ++FDL+ MLEYEPA R++LG AL HPFF RL PP++ SSR IS
Sbjct: 145 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWD--SSRDIS 498
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O35491|CLK2_MOUSE (Dual specificity protein kinase CLK2 OS=Mus musculus OX=10090 GN=Clk2 PE=1 SV=2) HSP 1 Score: 495.738 bits (1275), Expect = 1.321e-166 Identity = 239/356 (67.13%), Postives = 285/356 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL---PPHQRLHTLSSRRIS 2356
DD EGHLIY GD + RY IV TLGEGTFG+VV+CVD+ + +VALKIIKNVEKY+EAA LEINVL+ I EKDP++K L ++M +WFD++GHMCISFEL G S FDFLK+N+Y PYP+ VRH+++QLC AVKFLHD LTHTDLKPENILFVNSD L N ++KRD+R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD + GRYVRENC+PL RY T E ++ ++FDL+ MLEYEPA R++LG AL HPFF L PP+ +L SSR IS
Sbjct: 144 DDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPLRRYLTSEAEDHHQLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWD-SSRDIS 498
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P49762|DOA_DROME (Serine/threonine-protein kinase Doa OS=Drosophila melanogaster OX=7227 GN=Doa PE=1 SV=2) HSP 1 Score: 492.271 bits (1266), Expect = 1.113e-160 Identity = 231/356 (64.89%), Postives = 284/356 (79.78%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMAR------KSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRR 2350
DD +GHLIY GD++ RY+I+ TLGEGTFG+VV+ D ++ +ALKIIKNVEKYREAA LEIN L+ I +KDP +L +KM++WFD++GHMCI FE+ G SVFDFL+EN+Y PYP++ VRH++YQLC++VKFLHD LTHTDLKPENILFV+SD N K R+ R VKN+++RLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CI+FELY G TLFQTHDN+EHLAMMERILG PYRMAR K+KT +FYHGKLDWD S GRYVR++C+PL ++++ E+F L+ KMLEYEP+ RI+LG AL HPFF RLPPH R+ +S+++
Sbjct: 461 DDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYC-MALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQ 815
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3SX21|CLK3_BOVIN (Dual specificity protein kinase CLK3 OS=Bos taurus OX=9913 GN=CLK3 PE=2 SV=1) HSP 1 Score: 447.588 bits (1150), Expect = 4.373e-148 Identity = 211/347 (60.81%), Postives = 267/347 (76.95%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRM-ARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQR-LHT 2335
DDKEGHL+ GD + RY IV LGEGTFGKVVEC+D+ + +VALKII+NV KYREAA LEINVLK I+EKD E+K+L + M +WF+ +GHMCI+FEL G++ F+FLKEN++ PYP+ HVRH++YQLC A++FLH+ LTHTDLKPENILFVNS+ + N + +++ VKN+ IR+ DFGSATFDHEHH+TIV+TRHYR PEVILELGW++ CDVWSI CI+FE Y G+TLFQTH+N+EHL MME+ILG P M R K +FY G L WD S DGRYV+ENC+PL Y + E +++FDL+ +MLE++PA RI+L AL HPFF L P +R HT
Sbjct: 138 DDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDTLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHT 484
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q63117|CLK3_RAT (Dual specificity protein kinase CLK3 OS=Rattus norvegicus OX=10116 GN=Clk3 PE=1 SV=2) HSP 1 Score: 447.588 bits (1150), Expect = 5.847e-148 Identity = 209/343 (60.93%), Postives = 266/343 (77.55%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRM-ARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQR 2326
DDKEGHL+ GD + RY IV LGEGTFGKVVEC+D+ + +VALKII+NV KYREAA LEINVLK I+EKD E+K+L + M +WF+ +GHMCI+FEL G++ F+FLKEN++ PYP+ HVRH++YQLC A++FLH+ LTHTDLKPENILFVNS+ + N + +++ VKN+ IR+ DFGSATFDHEHH+TIV+TRHYR PEVILELGW++ CDVWSI CI+FE Y G+TLFQTH+N+EHL MME+ILG P M R K +FY G L WD S DGRYV+ENC+PL Y ++ E +++FDL+ +MLE++PA RI+L AL HPFF L P +R
Sbjct: 138 DDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER 480
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A5K3EUP7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 600.512 bits (1547), Expect = 0.000e+0 Identity = 279/405 (68.89%), Postives = 332/405 (81.98%), Query Frame = 2
Query: 1148 NRVAEARQRAKKLIELRKKSMG----------DLSNRTSVEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLH 2332
+RVAEARQRAKK IE RK SM D SN+ E P + SSK+ P DD +GHLIY D ++ RY I+KTLGEGTFGKVVEC+D+ + R+ALKIIKNV+KYREAA+LEINVL ++E+DP +YL +++L+WFD+YGH+C++F++ G SVFDFLKEN+Y YP+EHVRHISYQLC AV+F+HD LTHTDLKPENILF SD I V N K++R DR+VK S++RLIDFGSATFD++HHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFELYTGYTLFQTHDN+EHLAMMER LGH PYRM RKS+T FFYHG+LDWDFYS +GRYVRENCRPLLRYC +E+Q+T++MFDL+SKMLEY+PADRI L AALSHPFFLR+P HQRL+
Sbjct: 762 SRVAEARQRAKKFIEQRKLSMQQQQQQPQQNCDGSNQRLSEPPEEASSKAA--------PTDDVDGHLIYVPHDFVLDRYEIIKTLGEGTFGKVVECIDH-HTDTRIALKIIKNVDKYREAAMLEINVLNFLRERDPNDEYLCVRLLDWFDYYGHICLAFDILGLSVFDFLKENNYVGYPIEHVRHISYQLCHAVRFMHDNQLTHTDLKPENILFNRSDYISVHNRKKRRYDRIVKCSDVRLIDFGSATFDYDHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFELYTGYTLFQTHDNREHLAMMERTLGHIPYRMTRKSRTGFFYHGRLDWDFYSQEGRYVRENCRPLLRYCKEESQDTLDMFDLISKMLEYDPADRICLAAALSHPFFLRIPSHQRLN 1157
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A0X3PXS1 (Dual specificity protein kinase CLK2 OS=Schistocephalus solidus OX=70667 GN=CLK2 PE=4 SV=1) HSP 1 Score: 597.43 bits (1539), Expect = 0.000e+0 Identity = 273/394 (69.29%), Postives = 328/394 (83.25%), Query Frame = 2
Query: 1148 NRVAEARQRAKKLIELRKKSMGDLSNRTSVEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRL 2329
NR+AEARQRAKK IE RK N VE L+ + + + S P DD +GHLIY D I RY I++TLGEGTFGKVVEC D+ Q+ + +ALKIIKNV+KYREAA+LEINVL ++E+DPE +YL +++L+WFD+YGH+C++F++ G SVFDFLKEN+Y YP+EHVRHISYQLC AV+F+HD LTHTDLKPENILF SD I V N K++R DR+VK+S++RLIDFGSATFD++HHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFELYTGYTLFQTHDN+EHLAMMER LGH PYRM RKS+T FFYHG+LDWDFYS +GRYVRENCRPLLRYC +E+Q+T++MFDL+SKMLEY+PADRI L AA++HPFFLR+P HQRL
Sbjct: 474 NRLAEARQRAKKFIEQRKLCGQPPQNLIPVEAGLQEPEEPLDEASSRNLPVDDVDGHLIYAIHDWIFDRYEILRTLGEGTFGKVVECKDH-QTGENIALKIIKNVDKYREAAMLEINVLNFLRERDPEDEYLCVRLLDWFDYYGHICLAFDILGLSVFDFLKENNYVGYPIEHVRHISYQLCHAVRFMHDNQLTHTDLKPENILFKRSDYISVHNRKKRRYDRIVKSSDVRLIDFGSATFDYDHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFELYTGYTLFQTHDNREHLAMMERTLGHIPYRMTRKSRTGFFYHGRLDWDFYSQEGRYVRENCRPLLRYCKEESQDTLDMFDLISKMLEYDPADRIPLSAAMTHPFFLRIPVHQRL 866
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A564Z224 (Protein kinase domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS11334 PE=4 SV=1) HSP 1 Score: 594.349 bits (1531), Expect = 0.000e+0 Identity = 276/397 (69.52%), Postives = 332/397 (83.63%), Query Frame = 2
Query: 1148 NRVAEARQRAKKLIELRKKSMGDLSNRTSVE-EPLKVSSKSMQIS-DSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLH 2332
+RVAEARQRAKK IE RK SM + + E SS+ + S VPP DD +GHLIY D I+ RY I+KTLGEGTFGKVVEC+D+ S R+ALKIIKNV+KYREAA+LEINVL ++E+DP +YL +++L+WFD++GH+C++F++ G SVFDFLKEN+Y YP+EHVRHISYQLC AV+F+HD LTHTDLKPENILF SD I V N K++R DR+VK S++RLIDFGSATFD++HHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFELYTGYTLFQTHDN+EHLAMMER LGH PYRM RKS+T FFYHG+LDWDFYSP+GRYVRENCRPLLRYC +E+Q+T++MFDL+SKMLEY+PADRI L AA++HPFFLR+P +QRL+
Sbjct: 424 SRVAEARQRAKKFIEQRKLSMQQQQQQNQQDVESYDGSSQPFEDDMGSRVPPMDDVDGHLIYSPHDYILDRYEILKTLGEGTFGKVVECIDHHTDS-RIALKIIKNVDKYREAAMLEINVLNFLRERDPNDEYLCVRLLDWFDYFGHICLAFDILGLSVFDFLKENNYVGYPIEHVRHISYQLCHAVRFMHDNQLTHTDLKPENILFNRSDYISVHNRKKRRYDRIVKCSDVRLIDFGSATFDYDHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFELYTGYTLFQTHDNREHLAMMERTLGHIPYRMTRKSRTGFFYHGRLDWDFYSPEGRYVRENCRPLLRYCKEESQDTLDMFDLISKMLEYDPADRICLAAAMTHPFFLRIPSNQRLN 819
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A0V0J4B7 (Protein kinase domain-containing protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR97748 PE=4 SV=1) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 260/377 (68.97%), Postives = 318/377 (84.35%), Query Frame = 2
Query: 1199 KKSMGDLSNRTSVEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRL 2329
+K+ G L+N ++E SS+++ P DD +GHLIY D I RY I++TLGEGTFGKVVEC D+ Q+ + +ALKIIKNV+KYREAA+LEINVL ++E+DPE +YL +++L+WFD+YGH+C++F++ G SVFDFLKEN+Y YP+EHVRHISYQLC AV+F+HD LTHTDLKPENILF SD I V N K++R DR+VK+S++RLIDFGSATFD++HHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFELYTGYTLFQTHDN+EHLAMMER LGH PYRM RKS+T FFYHG+LDWDFYS +GRYVRENCRPLLRYC +E+Q+T++MFDL+SKMLEY+PADRI L AA++HPFFLR+P HQRL
Sbjct: 1277 RKAPGPLANAVPLDE---ASSRNL--------PVDDVDGHLIYAIHDWIFDRYEILRTLGEGTFGKVVECKDH-QTGENIALKIIKNVDKYREAAMLEINVLNFLRERDPEDEYLCVRLLDWFDYYGHICLAFDILGLSVFDFLKENNYVGYPIEHVRHISYQLCHAVRFMHDNQLTHTDLKPENILFKRSDYISVHNRKKRRYDRIVKSSDVRLIDFGSATFDYDHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFELYTGYTLFQTHDNREHLAMMERTLGHIPYRMTRKSRTGFFYHGRLDWDFYSQEGRYVRENCRPLLRYCKEESQDTLDMFDLISKMLEYDPADRIPLSAAMTHPFFLRIPVHQRL 1641
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A0X3Q7P9 (Protein kinase domain-containing protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR97748 PE=4 SV=1) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 260/377 (68.97%), Postives = 318/377 (84.35%), Query Frame = 2
Query: 1199 KKSMGDLSNRTSVEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRL 2329
+K+ G L+N ++E SS+++ P DD +GHLIY D I RY I++TLGEGTFGKVVEC D+ Q+ + +ALKIIKNV+KYREAA+LEINVL ++E+DPE +YL +++L+WFD+YGH+C++F++ G SVFDFLKEN+Y YP+EHVRHISYQLC AV+F+HD LTHTDLKPENILF SD I V N K++R DR+VK+S++RLIDFGSATFD++HHSTIVSTRHYRAPEVILELGWS+ CDVWSI CIIFELYTGYTLFQTHDN+EHLAMMER LGH PYRM RKS+T FFYHG+LDWDFYS +GRYVRENCRPLLRYC +E+Q+T++MFDL+SKMLEY+PADRI L AA++HPFFLR+P HQRL
Sbjct: 1272 RKAPGPLANAVPLDE---ASSRNL--------PVDDVDGHLIYAIHDWIFDRYEILRTLGEGTFGKVVECKDH-QTGENIALKIIKNVDKYREAAMLEINVLNFLRERDPEDEYLCVRLLDWFDYYGHICLAFDILGLSVFDFLKENNYVGYPIEHVRHISYQLCHAVRFMHDNQLTHTDLKPENILFKRSDYISVHNRKKRRYDRIVKSSDVRLIDFGSATFDYDHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFELYTGYTLFQTHDNREHLAMMERTLGHIPYRMTRKSRTGFFYHGRLDWDFYSQEGRYVRENCRPLLRYCKEESQDTLDMFDLISKMLEYDPADRIPLSAAMTHPFFLRIPVHQRL 1636
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk2a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:103024244]) HSP 1 Score: 486.108 bits (1250), Expect = 1.660e-163 Identity = 224/335 (66.87%), Postives = 272/335 (81.19%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLI GD++ RY IV TLGEGTFG+V+EC+D+ + VALKIIKNVEKY+EAA LEINVL+ I E+DPE+K L ++M +WFD++GHMC+SFEL S FDFLKEN+Y PY + VRH++YQ+C AVKFLHD LTHTDLKPENILFVNSD + N ++KRD+R+VKN+ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGW++ CDVWSI CI+FE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD S GRYVRENC+PL RY E +E ++FDL+ MLEYEP+ RI+L A+L HPFF
Sbjct: 165 DDEEGHLICRSGDVLQERYEIVGTLGEGTFGRVMECIDHRRGGSHVALKIIKNVEKYKEAARLEINVLEKINERDPENKNLCVQMFDWFDYHGHMCLSFELLALSTFDFLKENNYLPYSISQVRHMAYQICLAVKFLHDNKLTHTDLKPENILFVNSDFTITYNVEKKRDERMVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWNQPCDVWSIGCILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKPLRRYILSEAEEHHQLFDLIEAMLEYEPSKRITLAASLRHPFF 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk2a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:103024244]) HSP 1 Score: 486.108 bits (1250), Expect = 1.660e-163 Identity = 224/335 (66.87%), Postives = 272/335 (81.19%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLI GD++ RY IV TLGEGTFG+V+EC+D+ + VALKIIKNVEKY+EAA LEINVL+ I E+DPE+K L ++M +WFD++GHMC+SFEL S FDFLKEN+Y PY + VRH++YQ+C AVKFLHD LTHTDLKPENILFVNSD + N ++KRD+R+VKN+ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGW++ CDVWSI CI+FE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD S GRYVRENC+PL RY E +E ++FDL+ MLEYEP+ RI+L A+L HPFF
Sbjct: 165 DDEEGHLICRSGDVLQERYEIVGTLGEGTFGRVMECIDHRRGGSHVALKIIKNVEKYKEAARLEINVLEKINERDPENKNLCVQMFDWFDYHGHMCLSFELLALSTFDFLKENNYLPYSISQVRHMAYQICLAVKFLHDNKLTHTDLKPENILFVNSDFTITYNVEKKRDERMVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWNQPCDVWSIGCILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKPLRRYILSEAEEHHQLFDLIEAMLEYEPSKRITLAASLRHPFF 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk4a (dual specificity protein kinase CLK4-like [Source:NCBI gene;Acc:103029292]) HSP 1 Score: 442.58 bits (1137), Expect = 6.073e-147 Identity = 199/335 (59.40%), Postives = 264/335 (78.81%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLIY GD++ RY IV TLGEG FGKVVEC+D + RVALKIIKN+++YREAA+ E+ VL+ + D + +Y ++ML+WFDH+GH+CI+FEL G S FDFLKEN++ P+P++ +RH++YQ+ AVKFLH LTHTDLKPENILF++S+ L NSK KRD+R V+N++++++DFG+AT++HEHH+T+VSTRHYRAPEVILELGWS SCDVWSI CI+ E Y G TLFQTHD+KEHLAMMER+LG P M +K+ K + +H +LDWD +S GRYVR++C+PL +Y ++ + E+FDL+ KMLEY+ RISL A+ HPFF
Sbjct: 149 DDEEGHLIYHSGDILRARYEIVCTLGEGAFGKVVECIDRSNRNARVALKIIKNIDRYREAAMSEVEVLEQMNSLDCDRRYSCVRMLDWFDHHGHVCIAFELLGLSTFDFLKENNFQPFPVDQIRHMAYQIIRAVKFLHKNKLTHTDLKPENILFIDSEYDLEYNSKMKRDERTVRNADVKVVDFGNATYEHEHHTTVVSTRHYRAPEVILELGWSHSCDVWSIGCILIEYYLGSTLFQTHDSKEHLAMMERVLGPIPACMLQKTRKQRYVHHDRLDWDVHSSSGRYVRKHCKPLRQYMKSKSLDHEELFDLIEKMLEYDVTKRISLDEAIRHPFF 483
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000007667.2 (dual specificity protein kinase CLK4 [Source:NCBI gene;Acc:103034991]) HSP 1 Score: 430.639 bits (1106), Expect = 2.164e-142 Identity = 194/335 (57.91%), Postives = 262/335 (78.21%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTS-FFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLIY +GDM+ RY IV T+GEG FGKVVEC+D+ + RVALKIIKN+E+YREAAL E+ VLK + D E+++ ++ML+WFDH+GH+CI FEL G S +DFLKEN + P+ ++ +R ++YQLC AV FLH LTHTDLKPENILFVNS+ N+K KRD++ +KN ++++DFG+AT+DHE+H+++VSTRHYRAPEVILELGW++SCDVWS+ CI+ E Y G TLFQTHD+KEHLAMMER+LG P M +K+K + +H KLDWD ++ GRYVR++C+PL +Y + + + ++FDL+ KM+EY+ + RI+L AL HPFF
Sbjct: 143 DDEEGHLIYHNGDMLRARYEIVGTVGEGAFGKVVECIDHSKDGLRVALKIIKNLERYREAALSEVEVLKQMNSLDSENRFACVQMLDWFDHHGHICIVFELLGLSTYDFLKENDFMPFTVDQIRFMAYQLCRAVHFLHRNKLTHTDLKPENILFVNSEYDTEYNAKLKRDEKTLKNLHVKVVDFGNATYDHEYHTSVVSTRHYRAPEVILELGWNQSCDVWSLGCILIEYYLGITLFQTHDSKEHLAMMERVLGPIPVNMLQKTKKQRYVHHEKLDWDEHTSSGRYVRKHCKPLKQYMSSKTSDHEQLFDLLHKMMEYDVSKRITLEEALRHPFF 477
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk2b (CDC-like kinase 2b [Source:ZFIN;Acc:ZDB-GENE-060929-1126]) HSP 1 Score: 421.779 bits (1083), Expect = 1.515e-141 Identity = 196/291 (67.35%), Postives = 238/291 (81.79%), Query Frame = 2
Query: 1433 RVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
R+ALKIIKNVEKY+EAA LEINVL+ I+EKDPE+K+L ++M +WFD++GHMCISFEL S FDF+KEN+Y PY + VRH+++Q+C AVKFLHD LTHTDLKPENILFV+SD I N+++KR++R VK++ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS+ CDVWSI CI+FE Y GYTLFQTHDN+EHLAMMERI G P RM RK+ K +FY G+LDWD S GRYVRENC+PL RY E +E ++FDL+ MLEYEP R+ L + L HPFF
Sbjct: 7 RIALKIIKNVEKYKEAARLEINVLEKIREKDPENKHLCVQMFDWFDYHGHMCISFELLALSTFDFMKENNYLPYSLSQVRHMAFQICIAVKFLHDNKLTHTDLKPENILFVSSDFITNYNTEKKREERSVKDTSVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFEYYLGYTLFQTHDNREHLAMMERIQGPIPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKPLRRYVLSEAEEHHQLFDLLEGMLEYEPERRLLLSSCLRHPFF 297
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: clk2a (CDC-like kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-298]) HSP 1 Score: 486.493 bits (1251), Expect = 1.584e-164 Identity = 222/343 (64.72%), Postives = 278/343 (81.05%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQR 2326
DD++GHLIY GD + RY I+ TLGEGTFGKVV C+D+D+ ++ALKIIKNV+KYREAA LEINVL+ I EKDP +KYL ++M +WFD++GHMCI+FEL G S FDFLKEN+Y PYP+ VR ++YQLC+A+KFLHD LTHTDLKPENILFV+S+ + N ++KRD+R V+N++IR++DFGSATFD+EHHSTIVSTRHYRAPEV+LELGWS+ CDVWSI CI+FE Y G+TLFQTHDN+EHLAMMER LG P RM R++ K +F+HG LDWD S G+YVRENC+PL RY ++ + ++FDL+ KML+YEP+ RI+LG AL HPFF L QR
Sbjct: 151 DDEDGHLIYRIGDWLQARYEIISTLGEGTFGKVVHCIDHDRGKAKIALKIIKNVDKYREAARLEINVLEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENCKPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQDQR 493
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: dyrk2 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2804]) HSP 1 Score: 180.259 bits (456), Expect = 1.201e-48 Identity = 108/354 (30.51%), Postives = 182/354 (51.41%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFY-----HGKLDWDFYSPDGRYVRENCR----------------PLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPF 2299
DD++G ++ D + RY ++K +G+G+FG+VV+ D+ ++ VALK+++N +++ A EI +L+ ++++D E+ I +L F GH+C++FEL ++++ +K+N + + + VR ++ + + LH + H DLKPENIL K+ R S I++IDFGS+ F+H+ T + +R YRAPEV+L + D+WS+ CI+ EL TG L D + LA +LG P R+ + K S + H + +PDG V R LR C D + D + LE+EP++R++ AL HP+
Sbjct: 144 DDEQGSYVHVAHDHVAYRYEVLKVIGKGSFGQVVKAFDH-KTQTHVALKMVRNEKRFHRQAAEEIRILEHLRKQDRENSMNIIHLLESFTFRGHVCMTFELLSMNLYELIKKNKFQGFSLALVRKFAHSILQCLDTLHRNRIIHCDLKPENILL-------------KQPGR----SGIKVIDFGSSCFEHQRVYTYIQSRFYRAPEVVLGARYGPPIDMWSLGCILAELLTGSPLLPGEDEGDQLACAMELLGMPPQRLLAQGKRSRNFVSSRGHPRYCGVTEAPDGAVVLNAGRSRRGKPRGPPGSRELPAALRGCDDP-----LLLDFLRGCLEWEPSERLTPAQALRHPW 474
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007952.1 (pep scaffold:Pmarinus_7.0:GL476685:157428:173166:-1 gene:ENSPMAG00000007188.1 transcript:ENSPMAT00000007952.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 161.77 bits (408), Expect = 1.724e-44 Identity = 108/343 (31.49%), Postives = 171/343 (49.85%), Query Frame = 2
Query: 1316 HLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCR-------PLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFL--RLPP 2317
HL+Y RY +++ LG+G+FGKV++C+D+ +S + VA+K++ EI +LK +Q SK I+M+ F G C+ FEL ++ LK + +E VR + L +++ L D ++ H DLKP NI + ++ E++L DFG + FDHE H T + TRHYRAPEVIL+LG+S D+WS+ C + EL++G LF H N++ L + + G P M +S+ + D +S + R R R PL TDE+ D + L+++P R++ A+ H + R+PP
Sbjct: 6 HLLY--------RYEVLEVLGQGSFGKVLKCLDH-KSKEFVAIKVLNRARFNESVHRREIEILKRLQTARESSK--IIRMMEHFSFRGRECVVFELLNGNLRSQLKLTHRQGFGLEMVRLFAISLLKSLEQLRDANVIHGDLKPGNIGICSYEA-----------------GEVKLFDFGCSCFDHEEHFTKIQTRHYRAPEVILDLGYSFPADMWSLGCTLAELHSGQKLFPGHTNEDQLHSIMEVFGLPPQDMIEESRVQLGFFACKD---FSSNVRLNRGLVRVPGSRALPLALRTTDEH-----FTDFIRSCLQWDPEWRLTPHGAMDHEWVRAPRMPP 312
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007958.1 (pep scaffold:Pmarinus_7.0:GL476685:157443:173166:-1 gene:ENSPMAG00000007188.1 transcript:ENSPMAT00000007958.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 161.384 bits (407), Expect = 2.340e-44 Identity = 109/338 (32.25%), Postives = 170/338 (50.30%), Query Frame = 2
Query: 1316 HLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKT--SFFYHGK-LDWDFYSPDG--RYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLP 2314
HL+Y RY +++ LG+G+FGKV++C+D+ +S + VA+K++ EI +LK +Q SK I+M+ F G C+ FEL ++ LK + +E VR + L +++ L D ++ H DLKP NI + ++ E++L DFG + FDHE H T + TRHYRAPEVIL+LG+S D+WS+ C + EL++G LF H N++ L + + G P M +S+ FF K WD + G R PL TDE+ D + L+++P R++ A+ H ++R P
Sbjct: 6 HLLY--------RYEVLEVLGQGSFGKVLKCLDH-KSKEFVAIKVLNRARFNESVHRREIEILKRLQTARESSK--IIRMMEHFSFRGRECVVFELLNGNLRSQLKLTHRQGFGLEMVRLFAISLLKSLEQLRDANVIHGDLKPGNIGICSYEA-----------------GEVKLFDFGCSCFDHEEHFTKIQTRHYRAPEVILDLGYSFPADMWSLGCTLAELHSGQKLFPGHTNEDQLHSIMEVFGLPPQDMIEESRVQLGFFAITKPTHWDINNHRGLVRVPGSRALPLALRTTDEH-----FTDFIRSCLQWDPEWRLTPHGAMDHE-WVRAP 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007962.1 (pep scaffold:Pmarinus_7.0:GL476685:157455:173154:-1 gene:ENSPMAG00000007188.1 transcript:ENSPMAT00000007962.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 159.458 bits (402), Expect = 9.041e-44 Identity = 104/340 (30.59%), Postives = 164/340 (48.24%), Query Frame = 2
Query: 1316 HLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCR------------PLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPF 2299
HL+Y RY +++ LG+G+FGKV++C+D+ +S + VA+K++ EI +LK +Q SK I+M+ F G C+ FEL ++ LK + +E VR + L +++ L D ++ H DLKP NI + ++ E++L DFG + FDHE H T + TRHYRAPEVIL+LG+S D+WS+ C + EL++G LF H N++ L + + G P M +S+ F+ GR C PL TDE+ D + L+++P R++ A+ H +
Sbjct: 2 HLLY--------RYEVLEVLGQGSFGKVLKCLDH-KSKEFVAIKVLNRARFNESVHRREIEILKRLQTARESSK--IIRMMEHFSFRGRECVVFELLNGNLRSQLKLTHRQGFGLEMVRLFAISLLKSLEQLRDANVIHGDLKPGNIGICSYEA-----------------GEVKLFDFGCSCFDHEEHFTKIQTRHYRAPEVILDLGYSFPADMWSLGCTLAELHSGQKLFPGHTNEDQLHSIMEVFGLPPQDMIEESRVQL--------GFFVKSGRRFSVQCSNVRLKVPGSRALPLALRTTDEH-----FTDFIRSCLQWDPEWRLTPHGAMDHEW 300
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KNS1 (Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]) HSP 1 Score: 249.98 bits (637), Expect = 3.221e-72 Identity = 123/288 (42.71%), Postives = 185/288 (64.24%), Query Frame = 2
Query: 1304 DKEGHLIYGHGDMIM--GRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSI--------LVPNSKRKRDD-----RVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGH-FPYRMARKSKTSFFYHGK 2119
DK+GH +Y D+ GR+ + LG+GTFGKV++C+DN VA+K+I+ V++YREAA E+ +L+ I DP+ ++ + + FD+ H+C+ +L G+S++DF+ N + +P H++ I+ QL +V FLHD+ + HTDLKPENIL + I + SKR+R+ +++KN EI++IDFGSA F +E+H ++STRHYRAPE++L LGWS CD+WSIAC++ EL G +L+ H+N EH+AMM+RI G FP + K FY K
Sbjct: 294 DKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDK----MFYKSK 577
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: YAK1 (Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]) HSP 1 Score: 150.214 bits (378), Expect = 8.023e-38 Identity = 82/258 (31.78%), Postives = 142/258 (55.04%), Query Frame = 2
Query: 1352 RYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEK-DPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKL 2122
+Y ++ LG+GTFG+VV+C N + + +A+K++K+ +Y ++ E +L+++ +K DP +K+ F++M + F H H+C+ FEL ++++ LK+N + ++ +R + Q+ ++ L + L H DLKPENIL D E+++IDFGS+ + T + +R YRAPE+IL + +S S D+WS+ CI+ EL+ G +F L + LG+ P M K S + KL
Sbjct: 368 KYLVLDILGQGTFGQVVKC-QNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDK-----------------PELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKL 607
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KSS1 (Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]) HSP 1 Score: 97.0561 bits (240), Expect = 4.477e-22 Identity = 92/349 (26.36%), Postives = 154/349 (44.13%), Query Frame = 2
Query: 1343 IMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEK-------YREAALLEI-----NVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFL--KENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSA---TFDHEHHSTI-------VSTRHYRAPEVILELG-WSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILG--HFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETI--EMFDLVSKMLEYEPADRISLGAALSHPFF 2302
I +Y++V +GEG +G V + + S +VA+K I+ K RE LL N++ ++ + P S D + + EL + + + + +S +HV++ +YQ+ A+K +H + H D+KP N+L +NS N ++++ DFG A + T+ V+TR YRAPE++L ++ + D+WS CI+ E+ +G LF D L ++ +LG F KSK + Y L RP L + T ++ + +M DL+ KML++ P RIS AL HP+
Sbjct: 9 IPSQYKLVDLIGEGAYGTVCSAI-HKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVS----------IDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLL-LNS------------------NCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLP--------------MRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYL 313
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: FUS3 (Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]) HSP 1 Score: 92.8189 bits (229), Expect = 1.098e-20 Identity = 91/333 (27.33%), Postives = 152/333 (45.65%), Query Frame = 2
Query: 1343 IMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEK--YREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSA-----TFDHEHHSTIVSTRHYRAPEVILELG-WSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETI-----EMFDLVSKMLEYEPADRISLGAALSHPFF 2302
I +++ LGEG +G VV + + + VA+K I+ +K + L EI +LK + ++ + + I+ + F+++ + I EL + + S +H+++ YQ AVK LH ++ H DLKP N+L +NS+ D +V R+ID +A T + V+TR YRAPEV+L +S + DVWS CI+ EL+ +F D + L ++ I+G P+ D D + RE + L Y ++ + DL+ +ML ++PA RI+ AL HP+
Sbjct: 9 ISSDFQLKSLLGEGAYG-VVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIF-NIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSD---DHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLL-INSNC----------DLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGT-PHS---------------DNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYL 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: MCK1 (Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]) HSP 1 Score: 92.4337 bits (228), Expect = 1.554e-20 Identity = 79/334 (23.65%), Postives = 143/334 (42.81%), Query Frame = 2
Query: 1340 MIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSP----YPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSA-TFDHEHHS-TIVSTRHYRAPEVILELG-WSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETI------EMFDLVSKMLEYEPADRISLGAALSHPFF 2302
M++ YR +G G FG VV+ + IK V + E E+ +L++ + F L+ D+ + ++ E +++ ++ N Y P++H+R +YQ+ + +LH + + H D+KP N+L +L ++ DFGSA +H S + + +R YRAPE+I+ ++ D+W + C++ E+ G +FQ + L + ++LG + FF + D +S +PL + + E + DL+ K+L YEP R+S L+H FF
Sbjct: 33 MLVKEYR---KIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQ--IEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVL------------------KICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLG------PPDKRFIFFSNPAYDGPLFS----------KPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFF 327
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO33758 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR83]) HSP 1 Score: 436.802 bits (1122), Expect = 1.025e-145 Identity = 208/335 (62.09%), Postives = 259/335 (77.31%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD++GHLIY GD + RY + LGEGTFGKV+EC D ++ VA+K+IKN+EKYREAA LEI VL+ I +K+ K L IKML+WF+H+GHMC+ FE G SVFDF+K+N+Y PYP++ VRHISYQL AVKFLH++ LTHTDLKPEN+LFVNSD + N K+D R VK+S +RLIDFGSATF+HEHHST VSTRHYRAPEVILELGWS CD+WSI CI+FELYTG+TLFQTH+N+EHLAMMERI+G P A+KS KT +FY GKL+WD S G+YVRENC+PL +Y +++ F+L+ +LEY+P RI+ A+ HPFF
Sbjct: 107 DDEDGHLIYHKGDQLHSRYEVHCLLGEGTFGKVLECYDK-KTGDVVAVKVIKNIEKYREAAKLEIKVLEKINQKNRYGKSLCIKMLDWFNHHGHMCLVFEKMGLSVFDFMKDNNYEPYPLDQVRHISYQLIVAVKFLHEMKLTHTDLKPENMLFVNSDCDVFYNKDTKQDQRYVKSSHMRLIDFGSATFEHEHHSTTVSTRHYRAPEVILELGWSYPCDIWSIGCIMFELYTGFTLFQTHENREHLAMMERIIGPIPSDFAKKSRKTKYFYKGKLEWDEKSSSGKYVRENCKPLKKYMLSDSEGHQLFFNLLDYLLEYDPEKRITAKEAMQHPFF 440
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO36294 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ45]) HSP 1 Score: 179.104 bits (453), Expect = 4.983e-50 Identity = 89/254 (35.04%), Postives = 155/254 (61.02%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILG 2062
DD G + D + RY +++ LG+G+FG+VV+ +D+ ++ + VA+KII+N +++ + AL+E+ +L +++KD ++ + I M+ F H+CI+FEL G ++++ +K+N++ + + +R ++ L +K +H + H DLKPENIL R+R + I++IDFGS+ ++H+ T + +R YR+PEVIL L +S + D+WS CI+ ELYTGY LF + E LA + +LG
Sbjct: 42 DDDNGSYLKALHDHLAYRYEVLEVLGKGSFGQVVKALDH-KTGQHVAVKIIRNKKRFHQQALVEVKILDNLRKKDKDNTHNLIHMIEHFYFRNHLCITFELMGMNLYELIKKNNFQGFSLALIRRFAFALLHCLKVIHKEKIIHCDLKPENILL------------RQRG-----QTSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSFGCILAELYTGYPLFPGENEVEQLACIMEVLG 277
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO46144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQP1]) HSP 1 Score: 183.341 bits (464), Expect = 1.832e-49 Identity = 110/358 (30.73%), Postives = 186/358 (51.96%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYS-----PDGRYVRENCRP----------------LLRYCTDENQETIEMF-DLVSKMLEYEPADRISLGAALSHPFFLR 2308
DD++G I+ D I RY ++K +G+G+FG+VV+ +D+ +++ VALK+++N +++ A EI +L+ ++++D ++ + I ML F H+C++FEL ++++ +K+N + + + VR ++ + + LH + H DLKPENIL K+ R S I++IDFGS+ ++H+ T + +R YRAPEVIL + D+WS CI+ EL TGY LF D + LA +LG+ P ++ SK + + + Y PDG R L+ C D MF D + + LE++P+ R++ AL HP+ R
Sbjct: 149 DDEQGSYIHVPKDHIAYRYEVLKIIGKGSFGQVVKALDH-KTNTHVALKMVRNEKRFHRQAQEEIRILEHLKKQDKDNTHNIIHMLEHFTFRNHVCMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILL-------------KQQGR----SGIKVIDFGSSCYEHQRIYTYIQSRFYRAPEVILGARYGMPIDMWSFGCILAELLTGYPLFPGEDEGDQLACNMELLGYIPEKLRETSKRAKNFINSKGYPRYCTITTLPDGSVAVSGGRSRRGKTRGAPNSKTFVQALKGCDD------AMFIDFLKRCLEWDPSARMTPSQALRHPWLRR 482
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49238 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGV4]) HSP 1 Score: 158.303 bits (399), Expect = 1.502e-42 Identity = 111/347 (31.99%), Postives = 181/347 (52.16%), Query Frame = 2
Query: 1361 IVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSAT-FDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYR--MARKSKTSFFYH-------GKLDWDFYSPDGRYVRENCRP-------LLRYCTDENQ--------------ETIEMFDLVS---KMLEYEPADRISLGAALSHPF 2299
+++ LG GTFG+VV+C +++ VA+KI+K+ Y +EI++L + ++ E+ Y F++ + F H H C+ FE+ Q+++D+LK++ ++P P++H+R I Q+ A+ L + L H DLKPENI+ V+ D K+ RV ++IDFGSAT ST + +R+YRAPEVIL L + ES D+WS+ C+I EL+ G+ L+ + + + + G PY + +KTS F+ G L+W + + + RE P + D Q E I+ ++ VS +ML + RI+ ALSH F
Sbjct: 1 VLEFLGRGTFGQVVKCWKKG-TNELVAIKILKDHPSYARQGQIEISILAKLSAENSEA-YNFVRAIECFQHKNHTCLVFEMLQQNLYDYLKQSKFNPLPLKHIRPIVQQVLVALSKLRTLGLIHADLKPENIMLVDPD---------KQPFRV------KVIDFGSATHVSKVVCSTYLQSRYYRAPEVILGLPFCESIDMWSLGCVIAELFLGWPLYPGSSEFDQIRYIIQTQG-LPYDHLLNNATKTSRFFKKAINTHTGVLEWKLKNAN-EHERETKIPSKEARKYIFNSLDDIAQVNLSSSLTGNERIAEKIDRYEFVSLLKRMLTIDQEKRITPEEALSHQF 328
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO45187 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTC8]) HSP 1 Score: 157.918 bits (398), Expect = 1.182e-41 Identity = 105/383 (27.42%), Postives = 185/383 (48.30%), Query Frame = 2
Query: 1241 EPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFL--HDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRY--------VRENCRPLLRYCTD-------------------ENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
+P++ + Q +D DD+ I G+ RY I +G+G+FG+V + D+ Q + +A+KIIKN + + A +E+ +L+++ + DP+ KY +++ F H+C+ FEL +++D L+ ++ + R + Q+C A+ FL ++ + H DLKPENIL N K S I+++DFGS+ + + +R YR+PEV+L + ++ + D+WS+ CI+ E++TG LF + + + + +LG P + + + + +L PDG Y V+E P R D Q+ ++ DL+ +ML+Y+ RI AAL H FF
Sbjct: 45 DPVRPKKRPPQYNDGY----DDENYDYIVKAGEKWFDRYEIESLIGKGSFGQVCKAYDH-QEKEHIAVKIIKNKKPFLNQAQIEVKLLELMNKNDPDGKYYIVRLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLCSPELSIIHCDLKPENILLCNP-----------------KRSAIKIVDFGSSCQIGQRIYQYIQSRFYRSPEVLLGIPYNLAIDMWSLGCILVEMHTGEPLFSGANEFDQMMKIVEVLGMPPKDILDNAPKARKFFDRL------PDGSYQCLKVKDGVKEYLSPGSRKLHDILGCETGGPGGRRLGEAGHTLQDYLKFKDLILRMLDYDRKTRIVPYAALHHCFF 399
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: clk2a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101162379]) HSP 1 Score: 477.248 bits (1227), Expect = 5.476e-160 Identity = 221/335 (65.97%), Postives = 270/335 (80.60%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+EGHLI GD++ RY IV TLGEGTFG+V++C+D+ + VALKIIKNVEKY+EAA LEINVL+ I EKDP++K+L ++M +WFD++GHMC+SFEL S FDFLKEN+Y PY + VRH++YQ+C AVKFLHD LTHTDLKPENILFVNSD + N ++KR++R VKN+ +R++DFGSATFDHEHHSTIVSTRHYRAPEVILELGWS CDVWSI CI+FE Y G+TLFQTHDN+EHLAMMERILG P RM RK+ K +FY G+LDWD S G+YVRENC+PL RY E +E ++FDL+ MLEYEPA R++L +L HPFF
Sbjct: 167 DDEEGHLICRSGDVLQERYEIVGTLGEGTFGRVMKCIDHRRGGVSVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKFLCVQMYDWFDYHGHMCLSFELLALSTFDFLKENNYLPYSIGQVRHMAYQICLAVKFLHDSKLTHTDLKPENILFVNSDFTMSYNVEKKREERTVKNTSVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSHPCDVWSIGCILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDESSSAGKYVRENCKPLRRYLLSEAEEHHQLFDLIESMLEYEPARRLTLADSLKHPFF 501
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: clk2b (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101158555]) HSP 1 Score: 427.172 bits (1097), Expect = 1.069e-142 Identity = 201/338 (59.47%), Postives = 255/338 (75.44%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRL 2311
D K GHLIY GD++ RY I+ TLGEGTFGKVV+C+D+ + +++ALKIIKN EKYR A LEINVL+ I EKDP KY ++ML WF++ GH+CISF+L S FDFLK N++ PYP++ +R ++ Q+C AV FLHD LTHTDLKPENILFVNS+ LV N+++K +++ + ++ +RLIDFG+ATFD+EHHS ++STRHYRAPEVILELGWS CDVWSI CI+FE Y G+TLFQTHDNKEHLAMMER G P RM + S K +F G LDW+ S GR+V+ C+PL +Y +E FDL+ +MLEYEP+ RISL +AL HPFFL L
Sbjct: 35 DAKNGHLIYRSGDVLEDRYEIINTLGEGTFGKVVQCLDHGRGGRQIALKIIKNQEKYRNTAKLEINVLEKISEKDPLHKYHCVQMLEWFNYNGHICISFQLLSLSTFDFLKSNNFLPYPLQQIRLMAGQICRAVSFLHDNKLTHTDLKPENILFVNSNYSLVYNAEKKCNEKRINDTTVRLIDFGTATFDYEHHSVVISTRHYRAPEVILELGWSHPCDVWSIGCILFEYYEGFTLFQTHDNKEHLAMMERTHGPLPQRMIQSSRKQKYFCSGHLDWNESSKAGRFVKSKCKPLRQYLLSHGREHHHFFDLMERMLEYEPSKRISLHSALEHPFFLPL 372
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: clk4a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101161565]) HSP 1 Score: 432.565 bits (1111), Expect = 3.481e-142 Identity = 192/335 (57.31%), Postives = 260/335 (77.61%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYH-GKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD EGHLIY GDM+ RY IV TLGEG FGKVVEC+D+ + + +ALKIIKN+++YREAAL E+ VLK + D + +Y ++ML+WFD++GH+CI+FEL G S +DFLKEN++ P+P+EH+RH+++Q+ VKFLH LTHTDLKPENILFV+S+ + N +++RD+R +KN ++R++DFG+ATFDHEHH+++VSTRHYRAPEVIL+LGW SCDVWSI CI+ E Y G TLFQTHD+KEHLAMMER+LG P ++ K++ + H +LDWD S GRYVR++C+PL Y + ++ ++FDL+ KM+EY+P RI+L AL HPFF
Sbjct: 201 DDGEGHLIYHSGDMLRARYEIVYTLGEGAFGKVVECIDHANNGELIALKIIKNIDRYREAALSEVEVLKQLNSVDADKRYSCVRMLDWFDYHGHICIAFELLGLSTYDFLKENNFQPFPLEHIRHMAFQIIRGVKFLHKNKLTHTDLKPENILFVDSNYSMEYNREKRRDERTLKNPDVRIVDFGNATFDHEHHTSVVSTRHYRAPEVILDLGWDHSCDVWSIGCILIEYYLGTTLFQTHDSKEHLAMMERVLGPIPAKLLEKTRKRRYVHRSRLDWDGQSSSGRYVRKHCKPLKHYMWSKGEDHRQLFDLIEKMMEYDPTKRITLEQALHHPFF 535
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000019341.2 (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101170453]) HSP 1 Score: 332.028 bits (850), Expect = 2.718e-105 Identity = 164/335 (48.96%), Postives = 229/335 (68.36%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKS-KTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFF 2302
DD+ G L Y G + RY +V LGEG FG+V++C+D + + VA+KI++N E E A LEI VL+ I D ++K+ ++ML+WF H H+CI FEL G S F+FL++N + P+ +E +RH+++++ AV FLH LTHTDLKPENILFV+SD L + K R R ++ E++++DFG+ATFDH+HH ++VSTRHYRAPEVIL+LGW++SCDVWS+ C++FE Y G TLF +HD EHLAMM+ +LG P + +++ K F +L WD S G VRE CRP L+ E+ E ++ DL+S MLEY+ RI+L AL HPFF
Sbjct: 91 DDEGGQLDYHSGFVFKERYEVVSILGEGAFGRVMKCLDK-RKDEFVAVKILRNFENSYETARLEIAVLEEINSLDDDNKFACVRMLDWFKHKRHVCIVFELLGLSTFEFLRQNDFLPFSVEQIRHMAFRIFRAVSFLHRNKLTHTDLKPENILFVSSDFDLEDDPKTMRVCRKPRSLEVKVVDFGTATFDHQHHQSLVSTRHYRAPEVILDLGWNQSCDVWSLGCVLFEFYFGQTLFPSHDCMEHLAMMQEVLGPIPPHLLKQTGKKHFVQDDRLKWDQQSSSGDCVREPCRP-LKSIEAESDEEQQLLDLLSCMLEYDTCRRITLEEALWHPFF 423
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: dyrk4 (dual specificity tyrosine-phosphorylation-regulated kinase 4 [Source:NCBI gene;Acc:101159741]) HSP 1 Score: 178.718 bits (452), Expect = 4.470e-47 Identity = 111/379 (29.29%), Postives = 207/379 (54.62%), Query Frame = 2
Query: 1265 SMQISDSEVPP----CDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARK-SKTSFFYHGKLD-WDFYSPDGRYVRENCRPLLRYCTDENQETIEMF-DLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRRISVRSDTESS 2380
S +I S+ P DD+ G I D I R+ +++ +G+G+FG+V++C+D+ ++++ VA+K+I+N +++ AL+E+ +L+VI++KD ++ + I M +F H+CISFEL G ++++ +K+N++ + + +R ++ L ++ LH + H DLKPENIL S+R + I+++DFGS+ ++ + T + +R YR+PEVIL +S + D+WS+ CI+ EL+TGY LF E +A + +LG P + S+ F+ K + + + G+ R N + L + + T +F + + L ++P R++ L H + L R+ + + + SDT +S
Sbjct: 166 SQKIEGSQGAPHNSGYDDEHGSYIRVLHDHIAYRFEVLEVIGKGSFGQVLKCLDH-KTNELVAIKMIRNKKRFHHQALVELKILEVIKKKDKDNLHNVIHMKEYFYFRNHLCISFELLGVNLYELIKKNNFQGFSLALIRRFAHALLRCLQMLHKEKIIHCDLKPENILL----------SQRGPGN-------IKVVDFGSSCYEQQRVYTYIQSRFYRSPEVILGHPYSMAIDMWSLGCILAELHTGYPLFPGESEVEQIACIMEVLGMPPNDFVQSASRRKLFFDSKGNPRNITNSKGKKRRPNSKEL----SAALKTTDPLFLEFIKGCLTWDPTKRMTPDEGLQHQWILE-GNFNRVRSRAKTTVKKTSDTSTS 521
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000041213.1 (SMESG000041213.1) HSP 1 Score: 1483.77 bits (3840), Expect = 0.000e+0 Identity = 749/753 (99.47%), Postives = 751/753 (99.73%), Query Frame = 2
Query: 125 MSNRPPHHPQALNGPSKIITFKPKPPMIGSIKIESQAGKLKLYSGNNPSRESSYSPPADRKGVLTTSISLPYVDCDECEEPSNVCDVLQCSQPHNSSIDSTDEFAYDSVXXXXXXXXXXXXXXXXXXILLLIAKEKSVTNVNSIGSRXXXXXXXXXXXXXSIFKPPVTNKKQEKSFKSVSVQTEKLLSNPICSLCKQKCLELSNQLENLKVTIPTQVKPLPKIYQVAIETLFIPDFSTLMKPLFQTLGSVSSQSDIKLRATYNMNSIKRRRTLMPDGDVVRFINTTPTSVTLPIIITCGENYYTHVKFSMGMVINQNESRKEFVKETADEIDKVKNRSTKGNRVAEARQRAKKLIELRKKSMGDLSNRTSVEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRRISVRSDTESSR 2383
MSNRPPHHPQALNGPSKIITFKPKPPMIGSIK ESQ GKLKLYSGNNPSRESSYSPPADRKGVLTTSISLPYVDCDECEEPSNVCDVLQCSQPHNSSIDSTDEFAYDSVDDAFEADTESETEEEGDDILLLIAKEKSVTNVNSIGSRLKKMLLENKLLKLSIFKPP+TNKKQEKSFKSVSVQTEKLLSNPICSLC+QKCLELSNQLENLKVTIPTQVKPLPKIYQVAIETLFIPDFSTLMKPLFQTLGSVSSQSDIKLRATYNMNSIKRRRTLMPDGDVVRFINTTPTSVTLPIIITCGENYYTHVKFSMGMVINQNESRKEFVKETADEIDKVKNRSTKGNRVAEARQRAKKLIELRKKSMGDLSNRTSVEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRRISVRSDTESSR
Sbjct: 1 MSNRPPHHPQALNGPSKIITFKPKPPMIGSIKSESQTGKLKLYSGNNPSRESSYSPPADRKGVLTTSISLPYVDCDECEEPSNVCDVLQCSQPHNSSIDSTDEFAYDSVDDAFEADTESETEEEGDDILLLIAKEKSVTNVNSIGSRLKKMLLENKLLKLSIFKPPLTNKKQEKSFKSVSVQTEKLLSNPICSLCRQKCLELSNQLENLKVTIPTQVKPLPKIYQVAIETLFIPDFSTLMKPLFQTLGSVSSQSDIKLRATYNMNSIKRRRTLMPDGDVVRFINTTPTSVTLPIIITCGENYYTHVKFSMGMVINQNESRKEFVKETADEIDKVKNRSTKGNRVAEARQRAKKLIELRKKSMGDLSNRTSVEEPLKVSSKSMQISDSEVPPCDDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHTLSSRRISVRSDTESSR 753
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000033729.1 (SMESG000033729.1) HSP 1 Score: 488.419 bits (1256), Expect = 3.596e-162 Identity = 226/346 (65.32%), Postives = 277/346 (80.06%), Query Frame = 2
Query: 1301 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFF-YHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRLHT 2335
DD+ GHL+Y GD + RY I TLGEGTFGKVVEC+D + +VA+KIIKN+EKYREAA+LEINVLK +QEKDP+ KYL IKM +WF++ GH+CISF+L G SVF+FLKEN Y PYPME VRHI+YQ+CFAV FLH+ LTHTDLKPENILFVNSD ++ +SK+K+ + VVK+SEIRLIDFGSATFDHE HST+VSTRHYRAPEVILELGWS+ CDVWSI CI+FEL++G TLFQTHDN+EHLAMM+RILGH PY+M R + +F GKL W+ D ++VRENC+ L YC N+ +E+FDL+S+MLEY+P R+ L AL+H FF RLP +QR +
Sbjct: 323 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHN-VVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQS 667
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000071751.1 (SMESG000071751.1) HSP 1 Score: 383.645 bits (984), Expect = 1.701e-124 Identity = 182/334 (54.49%), Postives = 242/334 (72.46%), Query Frame = 2
Query: 1304 DKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFFYH--GKLDWDFYSPDGRYVRENCRPLLRYCTDENQ-ETIEMFDLVSKMLEYEPADRISLGAALSHP 2296
D +G+L+ ++ RY+I+K LGEGTFG+V +C D + VA+K+IK VEKYREAALLEI VL++I++ DP+ + L I L+ F+++GHMCI F L G SVFDFLK N Y YPM VR+++YQ+ AV FLH + LTHTDLKPENILFVN + + K++ ++++++ I++ID GSATF+ EHH+TIV+TRHYR EVILELGWS CDVWSI CI+FELYTG T+F THDN EHLAMMERILGH P RM RKSK ++ G+L WD S +G+YVR +PL RY T + + +++FDL+ +MLEY P RI++ +L HP
Sbjct: 134 DNDGYLVMKEDQLLKKRYKILKLLGEGTFGRVAQCKDLKNHNNEVAVKVIKAVEKYREAALLEIKVLELIKKTDPQGRKLVIFALDSFNYHGHMCIVFPLLGPSVFDFLKANHYVGYPMRQVRYMTYQISKAVDFLHSLKLTHTDLKPENILFVNGAYDMQYDESTKKNVKILRDASIQIIDLGSATFEDEHHTTIVATRHYRPLEVILELGWSYPCDVWSIGCILFELYTGITMFMTHDNIEHLAMMERILGHLPVRMTRKSKKRKYFDDCGRLKWDGESKEGKYVRGEVKPLRRYITRHDDIKELDLFDLIQEMLEYNPKKRITMSESLRHP 467
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000065189.1 (SMESG000065189.1) HSP 1 Score: 222.631 bits (566), Expect = 8.466e-64 Identity = 106/252 (42.06%), Postives = 164/252 (65.08%), Query Frame = 2
Query: 1340 MIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSK 2095
MI R+ LGEGTFGKV+ C+D + +R+ALK+ K +EKY++ A EI +L I+++DP+ + + + WF+ H+ + F G+ ++++LK + + VRHIS+Q+ AV FLH + + HTD+KPEN+LFV+S+ + + + + +++I LID G+ + +E I+ TR+YR PEV LE+GW++S D+WSI C++FELY+G +LFQ HD+ EHL MME IL FP +M KSK
Sbjct: 232 MIKDRFFFTGLLGEGTFGKVISCLDQRLNDERIALKVSKRLEKYKKLAKHEIEILVRIRKRDPKGENYVVILKAWFELDCHIIMIFPQYGEDLYNYLKSIDHHGMKLGDVRHISWQMWRAVDFLHGLTIIHTDIKPENLLFVSSEYKYIESKNSESKIKYPSSTDIVLIDLGNGVYGNERKPRIIVTRYYRPPEVYLEIGWNKSVDIWSIGCVMFELYSGRSLFQCHDDLEHLWMMEYILKEFPEQMINKSK 483
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000078436.1 (SMESG000078436.1) HSP 1 Score: 188.734 bits (478), Expect = 2.425e-51 Identity = 106/331 (32.02%), Postives = 186/331 (56.19%), Query Frame = 2
Query: 1352 RYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLH-DIHLTHTDLKPENILFVNSDSILVPNSKRKRDDR---VVKNSEIRLIDFGSA-TFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTS-FFYHGKLDWDFYSPDGRYVRENCRPLLRYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQR 2326
RY VK LGEGTFG V+EC+D ++ + VA+K+ KN+ E L E+++LK I + ++ WF +C+ F G +++ F+K+ + P PME ++ I+YQL A+ FLH + L HTDLKPENI+ + I +K++R D+ + +I++IDFG+A T ++ ++ TR+YRA EV+L + W+ D WS+ CI++EL TG LF T+++ HLA++++I+GH P M R K + F +G + + + Y+ E+ + + + ++ ++S +++ P R + + F ++P + +
Sbjct: 177 RYIFVKDLGEGTFGYVLECLDCEKRRQPVAIKVSKNLLATTEKLLNEVSILKKINDIYNSPNNPCATLIEWFKLEKRLCLVFHRYGDNIYHFMKKRQFKPLPMEFIKQIAYQLLSAILFLHENCDLIHTDLKPENIVLCSPIYI----TKQERGDKANMLPSKYDIKIIDFGNALTNKGFKYTKVIGTRYYRAVEVMLGVPWNYKIDYWSLGCILYELVTGKILFMTNNDSHHLALIDKIIGHLPEEMTRTCKKAHLFLNGHFNKA--AINDYYLIESAEYIENHFKHSSFQSHSFTAMISSLIQINPESRPEMKEFIHSHMFAKVPEYLK 501 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017052 ID=SMED30017052|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2517bpback to top protein sequence of SMED30017052-orf-1 >SMED30017052-orf-1 ID=SMED30017052-orf-1|Name=SMED30017052-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=754bp MSNRPPHHPQALNGPSKIITFKPKPPMIGSIKIESQAGKLKLYSGNNPSRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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