Proton myo-inositol cotransporter
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30017038 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of Proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A13 (solute carrier family 2 member 13 [Source:HGNC Symbol;Acc:HGNC:15956]) HSP 1 Score: 137.502 bits (345), Expect = 4.469e-34 Identity = 84/286 (29.37%), Postives = 145/286 (50.70%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQL---VDVRYLKR-----NQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RGR++TI + +T G F ASVV+ +Y +L AVPA+ G L +PES RWL+ K + +A ++ +++ + ++ ++ E+ +++ ++CR+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +L+I+A+ L V R + QN C + C++ C +D + G+
Sbjct: 187 IASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQK-----DGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRG------NQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNE--------CMLDPDCGF 453 HSP 2 Score: 92.0485 bits (227), Expect = 4.122e-19 Identity = 50/111 (45.05%), Postives = 64/111 (57.66%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y FC P+ + W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+ NW FN V++T Y T F++Y+ F G+ IY PE +EEI
Sbjct: 498 YNFC-PTPYS--WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605
BLAST of Proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A13 (solute carrier family 2 member 13 [Source:HGNC Symbol;Acc:HGNC:15956]) HSP 1 Score: 92.8189 bits (229), Expect = 6.200e-20 Identity = 56/171 (32.75%), Postives = 93/171 (54.39%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMY 721
I+S P+YIAE++P +RGR++TI + +T G F ASVV+ +Y +L AVPA+ G L +PES RWL+ K + +A ++ +++ N T ++ ++ E+ +++ ++CR+L R+ L++GC LQM QL GIN +MY
Sbjct: 187 IASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-----WRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMR----GNQT--IDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMY 346
BLAST of Proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A1 (solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005]) HSP 1 Score: 73.1738 bits (178), Expect = 3.483e-13 Identity = 59/242 (24.38%), Postives = 123/242 (50.83%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD 931
+++ P+Y+ E++P +RG + T++Q+ + G+ +A V + D P + II I PAL I + PES R+LL ++N + A V++KL+ +++T ++ + E + + + + + + R+ +++ LQ+ QL GIN + YY+ S+F+K ++ ++ T +N + V+ ++++ GRR L LI L G+ +++ + L L++
Sbjct: 135 LTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLD-SIMGNKDLWPLLLSIIFI----PALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGT--ADVTHDLQEMKEESRQMMREKKVT-------ILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK---AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLE 359
BLAST of Proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A2 (solute carrier family 2 member 2 [Source:HGNC Symbol;Acc:HGNC:11006]) HSP 1 Score: 70.0922 bits (170), Expect = 3.851e-12 Identity = 62/247 (25.10%), Postives = 118/247 (47.77%), Query Frame = 2
Query: 215 STCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATL---NYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIP-----ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD 931
S P+YI EI P +RG + T +Q+ + G+ ++ ++ NY I+L V A+ + + PES R+L K +DE ++ + LK++ +I E + EA+ ++K + ++ + R+ +++ L + Q GING+ YY+ S+FQ T I ++ T + +N++ + V+ L++K GRR L LI + G+ + ++V L L++
Sbjct: 169 SGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNY--------DLWHILLGLSGVRAILQSLLLFFCPESPRYLYIK--LDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEAS-----------SEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ---TAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLN 391
BLAST of Proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A12 (solute carrier family 2 member 12 [Source:HGNC Symbol;Acc:HGNC:18067]) HSP 1 Score: 69.3218 bits (168), Expect = 6.906e-12 Identity = 34/101 (33.66%), Postives = 59/101 (58.42%), Query Frame = 3
Query: 1116 INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFP----IGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+ W+ L +++YV +F+IG+GP+PW+V SEI+P R MAL+++ NW N +++T IGL +IY+ +L + + PE ++E+I
Sbjct: 460 LKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQI 560
BLAST of Proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.3 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q21455]) HSP 1 Score: 127.102 bits (318), Expect = 3.823e-31 Identity = 82/286 (28.67%), Postives = 146/286 (51.05%), Query Frame = 2
Query: 212 SSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVE---NILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKR-NQNNICDNF-----LACDDWVSYHCEYCQIDENSGY 1042
+S P+Y++E +P IRG+++T +Q+ +T GL +A+++ +Y P + M AVPA+ + L +PES RWL R EA EV+ ++ + TE+V+ N + + E + + + RIL RK +++G LQM QL GIN +MYY ++ + + +W + + IN + +F+ L++++GRR L L+S+ G+I L+ + V+ L++ L+ +Q N N+ A +C++C DEN G+
Sbjct: 138 ASMIVPIYVSEASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYVDPDQVGWRLM---FAFAAVPAIIQFVCFLFLPESPRWLYEHGRTVEAREVLTRIY----NGHTEWVDYEINEISFSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAGVKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMIGVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSNCDFCVTDENCGF 416 HSP 2 Score: 71.2478 bits (173), Expect = 7.066e-13 Identity = 33/93 (35.48%), Postives = 55/93 (59.14%), Query Frame = 3
Query: 1140 MILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGL----YETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
M+ Y++SF+ G P+PWV+ +E YP W RST +++ST NW FN V++T + Y TF+IY T+ + ++ PE +++E+
Sbjct: 475 MVFYLLSFSAGYAPLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYCGCTMVALVFVFFFVPETKGYSIDEV 567
BLAST of Proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.3 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q21455]) HSP 1 Score: 127.102 bits (318), Expect = 3.823e-31 Identity = 82/286 (28.67%), Postives = 146/286 (51.05%), Query Frame = 2
Query: 212 SSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVE---NILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKR-NQNNICDNF-----LACDDWVSYHCEYCQIDENSGY 1042
+S P+Y++E +P IRG+++T +Q+ +T GL +A+++ +Y P + M AVPA+ + L +PES RWL R EA EV+ ++ + TE+V+ N + + E + + + RIL RK +++G LQM QL GIN +MYY ++ + + +W + + IN + +F+ L++++GRR L L+S+ G+I L+ + V+ L++ L+ +Q N N+ A +C++C DEN G+
Sbjct: 138 ASMIVPIYVSEASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYVDPDQVGWRLM---FAFAAVPAIIQFVCFLFLPESPRWLYEHGRTVEAREVLTRIY----NGHTEWVDYEINEISFSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAGVKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMIGVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSNCDFCVTDENCGF 416 HSP 2 Score: 71.2478 bits (173), Expect = 7.066e-13 Identity = 33/93 (35.48%), Postives = 55/93 (59.14%), Query Frame = 3
Query: 1140 MILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGL----YETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
M+ Y++SF+ G P+PWV+ +E YP W RST +++ST NW FN V++T + Y TF+IY T+ + ++ PE +++E+
Sbjct: 475 MVFYLLSFSAGYAPLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYCGCTMVALVFVFFFVPETKGYSIDEV 567
BLAST of Proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.2 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q9XXQ9]) HSP 1 Score: 108.997 bits (271), Expect = 5.111e-25 Identity = 78/299 (26.09%), Postives = 135/299 (45.15%), Query Frame = 2
Query: 212 SSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENIL---EANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD---------------VRYLKRNQNNICDNFLACDDWV-SYHCEYCQIDENSGYTCV 1051
+S P+Y+ E +P +RG +++ + + ++FG +A+++ +Y P + M +PAL + + +PE+ RWL ++A +V+ K+ TE++E L + + E++++ ++ RIL K +G LQ QL GIN ++YY + + N +W + +L+ NLI F I+K+GRRKL L S G++ SLV+I V+ LV Y + C CD V S HC +C+ E C+
Sbjct: 136 ASMVVPVYLGEASPTHVRGTLVSAFAMMISFGQVVANIMGGVFSYWEPYTIGWRLM---FAFAGIPALIQFVCFIFLPETPRWLYENGHTEQAEQVLEKIY----GGNTEWIEYELAEIKTYAEERQKQMEEEKKSGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSAGIENYHTIIWISVILSICNLIGPFAPMFFIEKLGRRKLFLFSCAGVVVSLVLIGVSFLLVGNDSAPNFDRSAYLLAGNYQSNGEAESCLMLSNCDSCVTSEHCGFCEDSETRTGFCL 427 HSP 2 Score: 58.9214 bits (141), Expect = 5.315e-9 Identity = 34/93 (36.56%), Postives = 54/93 (58.06%), Query Frame = 3
Query: 1140 MILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMT----VFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
M +Y+++F+ G +PWV+ SE YP W RST +++ST +NW FN + +T I Y FW+Y+ FT+ IY PE +++E+
Sbjct: 479 MGVYLLTFSCGFTSLPWVLNSEFYPMWARSTCVSISTLSNWVFNLIIALTYLSLTHAITKYGAFWLYAIFTIIAFIFIYFLVPETTGYSIDEV 571
BLAST of Proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.1 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q9XXR3]) HSP 1 Score: 102.064 bits (253), Expect = 9.340e-23 Identity = 78/290 (26.90%), Postives = 133/290 (45.86%), Query Frame = 2
Query: 212 SSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKL----KQIPESNITE---FVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD---VRYLKRNQ--NNICDNFLACDDWVSY-HCEYCQIDENSGY 1042
+S P+Y+ E P +RG ++ + + ++FG +A++ +Y P + + M AVP++ + + +PE+ RWL E EV+ K+ K+ E + E F E+ + N E+ ++ RIL K +G LQ QL GIN ++YY + + +N +W + LL+ N I FV LI+K+GRR + L S ++ SLV I V LV+ L NQ +N ++ ++Y +C+YC + G+
Sbjct: 135 ASMIVPVYLGETAPTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPYNVGWRLM---FAFAAVPSIIQFVCFMFLPETPRWLYENGFETETREVLEKVYNGDKEWVEYEMAEIIAFNEDQAKEN--------EKAHASGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSGISNNHTTIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDSAATLPANQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGF 413 HSP 2 Score: 71.633 bits (174), Expect = 5.031e-13 Identity = 35/91 (38.46%), Postives = 53/91 (58.24%), Query Frame = 3
Query: 1146 LYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFP----IGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+Y+++F+ G +PWV+ SE YP W RST +A+STT+NW FN + +T IG Y FW+Y+ T+ I PE ++EE+
Sbjct: 473 VYLLTFSSGFTSLPWVLNSEFYPMWARSTCVAISTTSNWVFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEEV 563
BLAST of Proton myo-inositol cotransporter vs. Ensembl Celegans
Match: fgt-1 (Facilitated glucose transporter protein 1 [Source:UniProtKB/Swiss-Prot;Acc:O44827]) HSP 1 Score: 59.3066 bits (142), Expect = 3.727e-9 Identity = 68/275 (24.73%), Postives = 121/275 (44.00%), Query Frame = 2
Query: 212 SSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLS-KNRIDEAIEVVRKLKQIPE--SNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTL-VMGCSLQML--AQLIGINGLMYYANSLFQKY-VTNNIKIYLWFTPLLTFINLISSFVAYKLID--KIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSYHC 1009
SS P+++ EI+P +RG + +++Q+ +T + L S + + DR P+I VPA+ L ++ PES ++ ++ + + +EA ++KL+ + + I E A V + +GD L M ++ M+ QL GIN M+Y+ +F+ +T N Y T + +N+I + ++ L+D K GRR L L L G+ S +++ L + QN+ D W SY
Sbjct: 152 SSALVPMFLTEISPNNLRGMLGSLHQLLVTIAI-LVSQIFGLPHLLGTGDR----WPLIFAFTVVPAVLQLALLMLCPESPKYTMAVRGQRNEAESALKKLRDTEDVSTEIEAMQEEATAAGVQEKPK---------------MGDMFKGALLWPMSIAIMMMLAQQLSGINVAMFYSTVIFRGAGLTGNEPFYA--TIGMGAVNVIMTLISVWLVDHPKFGRRSLLLAGLTGMFVSTLLLVGALTI---------QNS------GGDKWASYSA 389 HSP 2 Score: 52.373 bits (124), Expect = 5.519e-7 Identity = 31/92 (33.70%), Postives = 48/92 (52.17%), Query Frame = 3
Query: 1140 MILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIG---LYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
++L+VISFA G G IPW SEI+ + R +++ NW N V +T PI +F+I+S F I ++ PE ++E+I
Sbjct: 393 VLLFVISFATGPGAIPWFFVSEIFDSSARGNANSIAVMVNWAANLLVGLTFLPINNLMQQYSFFIFSGFLAFFIFYTWKFVPETKGKSIEQI 484
BLAST of Proton myo-inositol cotransporter vs. Ensembl Fly
Match: CG6484 (gene:FBgn0034247 transcript:FBtr0086903) HSP 1 Score: 66.2402 bits (160), Expect = 5.134e-20 Identity = 70/252 (27.78%), Postives = 122/252 (48.41%), Query Frame = 2
Query: 224 CPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRY-LKRNQNNICDNF 976
P+Y EIT +RG I + +Q+ + G+ +V A L + I ++ +P +F +I +PES +L K R D+A + ++ L+ +++I + ++ ILE + Q+Q + + + L I K L + LQ+ Q GIN +++Y+ S+F+ ++ T ++ + S+ VA +IDK GRR L LI S V++AV+ L+ V + LK N DNF
Sbjct: 124 APMYCTEITATALRGTIGSFFQLLIVSGVLYGYLVGAFL----------PLLTINILCAILPVIFAIIHFF-MPESPVYLAMKGRNDDAAKALQWLRG-KDADIDDELKEILEES-------QKQIDMPQVNILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDA--TLIIGVTQVTSTLVAVAIIDKAGRRILLLI-------SGVLMAVSTALMGVYFQLKENDPASMDNF 347 HSP 2 Score: 50.8322 bits (120), Expect = 5.134e-20 Identity = 38/115 (33.04%), Postives = 66/115 (57.39%), Query Frame = 3
Query: 1098 NPSTI-NINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFP-----IGLYETFWIYSAFTLCGIALIYRNF--PEMNQANMEEILHVL 1418
+P+++ N W+ + + +++I F+IG GP+PW+V +E++ +S +++ T+NW F VT+ +FP IG TFWI++A + IA Y F PE + EI +L
Sbjct: 340 DPASMDNFGWLPISSICIFIIFFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTL-LFPILKSSIGPGPTFWIFTAIAV--IAFFYSLFFVPETKGKTIIEIQDLL 451
BLAST of Proton myo-inositol cotransporter vs. Ensembl Fly
Match: Glut1 (gene:FBgn0264574 transcript:FBtr0333504) HSP 1 Score: 75.485 bits (184), Expect = 4.433e-14 Identity = 69/234 (29.49%), Postives = 114/234 (48.72%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGI-IFSLVI 904
++++ P+YI+EI P +RG + T+ Q+ +T GL L+ V+ + + PI+L PA+ LI + PES R+LL +K +EA + +R+L+ S E E+I E E ++C R L++G +Q+ Q GIN + YY+ SLF + + T + I ++ + V+ L+D+ GRR L L L G+ IFS+ I
Sbjct: 372 LNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILG-----TNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRA---SGSVE--EDIEEMRAEERAQQSESHISTMELIC----SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE-ESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFI 590
BLAST of Proton myo-inositol cotransporter vs. Ensembl Fly
Match: Glut1 (gene:FBgn0264574 transcript:FBtr0333508) HSP 1 Score: 75.485 bits (184), Expect = 5.097e-14 Identity = 69/234 (29.49%), Postives = 114/234 (48.72%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGI-IFSLVI 904
++++ P+YI+EI P +RG + T+ Q+ +T GL L+ V+ + + PI+L PA+ LI + PES R+LL +K +EA + +R+L+ S E E+I E E ++C R L++G +Q+ Q GIN + YY+ SLF + + T + I ++ + V+ L+D+ GRR L L L G+ IFS+ I
Sbjct: 372 LNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILG-----TNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRA---SGSVE--EDIEEMRAEERAQQSESHISTMELIC----SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE-ESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFI 590 HSP 2 Score: 51.2174 bits (121), Expect = 2.078e-6 Identity = 33/114 (28.95%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 1116 INWILLLGMIL---YVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTM------------TVFPIGLY-ETFWIYSAFTLCGIALIYRNFPEMNQANMEEIL 1409
I+W+ L ++ +V+ FA+G G IPW++T+E++ R + MA++ NW NF V + T P ++ FWI++ Y+ PE EEIL
Sbjct: 600 IDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFT----------YKKVPETKNKTFEEIL 703
BLAST of Proton myo-inositol cotransporter vs. Ensembl Fly
Match: Glut1 (gene:FBgn0264574 transcript:FBtr0333509) HSP 1 Score: 75.0998 bits (183), Expect = 5.637e-14 Identity = 69/234 (29.49%), Postives = 114/234 (48.72%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGI-IFSLVI 904
++++ P+YI+EI P +RG + T+ Q+ +T GL L+ V+ + + PI+L PA+ LI + PES R+LL +K +EA + +R+L+ S E E+I E E ++C R L++G +Q+ Q GIN + YY+ SLF + + T + I ++ + V+ L+D+ GRR L L L G+ IFS+ I
Sbjct: 372 LNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILG-----TNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRA---SGSVE--EDIEEMRAEERAQQSESHISTMELIC----SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE-ESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFI 590 HSP 2 Score: 50.8322 bits (120), Expect = 2.365e-6 Identity = 33/114 (28.95%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 1116 INWILLLGMIL---YVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTM------------TVFPIGLY-ETFWIYSAFTLCGIALIYRNFPEMNQANMEEIL 1409
I+W+ L ++ +V+ FA+G G IPW++T+E++ R + MA++ NW NF V + T P ++ FWI++ Y+ PE EEIL
Sbjct: 600 IDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFT----------YKKVPETKNKTFEEIL 703
BLAST of Proton myo-inositol cotransporter vs. Ensembl Fly
Match: Glut1 (gene:FBgn0264574 transcript:FBtr0333507) HSP 1 Score: 75.0998 bits (183), Expect = 5.832e-14 Identity = 69/234 (29.49%), Postives = 114/234 (48.72%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGI-IFSLVI 904
++++ P+YI+EI P +RG + T+ Q+ +T GL L+ V+ + + PI+L PA+ LI + PES R+LL +K +EA + +R+L+ S E E+I E E ++C R L++G +Q+ Q GIN + YY+ SLF + + T + I ++ + V+ L+D+ GRR L L L G+ IFS+ I
Sbjct: 372 LNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILG-----TNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRA---SGSVE--EDIEEMRAEERAQQSESHISTMELIC----SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE-ESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFI 590 HSP 2 Score: 51.2174 bits (121), Expect = 1.948e-6 Identity = 33/114 (28.95%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 1116 INWILLLGMIL---YVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTM------------TVFPIGLY-ETFWIYSAFTLCGIALIYRNFPEMNQANMEEIL 1409
I+W+ L ++ +V+ FA+G G IPW++T+E++ R + MA++ NW NF V + T P ++ FWI++ Y+ PE EEIL
Sbjct: 600 IDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFT----------YKKVPETKNKTFEEIL 703
BLAST of Proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a13b (solute carrier family 2 member 13b [Source:ZFIN;Acc:ZDB-GENE-090812-1]) HSP 1 Score: 139.813 bits (351), Expect = 3.255e-35 Identity = 90/294 (30.61%), Postives = 149/294 (50.68%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV-----DVRYLKRN---QNNICDNFLACDDWVSYHCEYCQIDENSGYTCVNYGAN 1066
I+S P+YIAE++P +RG+++T+ + +T G F+ASVV+ +Y P D +L VPA +G L +PES RWLL K A+ V+R+++ + ++ E E+I +++ +L R+L AR+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W F N + + V L++++GRR+L + SL G SL+++A L V + N N+ C N+ CE C +D + G+ YG N
Sbjct: 141 IASMTVPVYIAEVSPPDLRGQLVTVNTLFITGGQFIASVVDGAFSYL-PHD----GWRFMLGLSVVPAALQFLGFLFLPESPRWLLQKGFTQNALLVLRQIRG--DVDVEEEFESIR-----CSIQEEQRDVAGGPVLWRMLASPPARRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVQDDQMAIWLAAGTAFTNFLFTLVGVWLVERVGRRRLTMASLLGTAVSLMVLAAGFLLSAQASPPVTFHPSNPSIHNSTCGNY--------GFCESCMLDPDCGFC---YGLN 411 HSP 2 Score: 87.0409 bits (214), Expect = 1.098e-17 Identity = 44/100 (44.00%), Postives = 58/100 (58.00%), Query Frame = 3
Query: 1119 NWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+W++LLG+ILY+ FA GMGP+PW V SEIYP W RST A S NW N V++T + Y T F++Y+A L G + PE +EEI
Sbjct: 458 SWVVLLGLILYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAQYLTYYGAFFLYAALALLGFVFVSGCLPETKGLRLEEI 557
BLAST of Proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a3b (solute carrier family 2 member 3b [Source:ZFIN;Acc:ZDB-GENE-121031-5]) HSP 1 Score: 72.7886 bits (177), Expect = 6.757e-21 Identity = 64/264 (24.24%), Postives = 129/264 (48.86%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVN--ATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIP--ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLK----RNQNNICDN 973
+S+ P+Y+ EI P +RG T++Q+ + G+ +A ++ + L + + + ++ +F L ES R+LL S N+ DEA + + L+ E +I E + ++ ++ +K+ + + + R+ +++ LQ+ QL GIN +MYY+ +F+ I ++ T + +N + + V+ L+++ GRR L LI L G+ F ++++ ++L+LVD K +N I D+
Sbjct: 139 LSTGLTPMYVGEIAPTALRGAFGTLHQLGVVIGILVAQILGLESLLGSQTLWPLLLALTALPAVIQSIMLIFCL-------ESPRYLLISLNKEDEARQALTSLRGHSDVEDDIREMKDEAMKMSM-----------EKRVSIPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRNA---GITEPVFATIGMGVVNTVFTVVSLFLVERAGRRTLHLIGLTGMTFCVLLVTISLKLVDSEIEKAKLLQNGTAIIDS 381 HSP 2 Score: 47.7506 bits (112), Expect = 6.757e-21 Identity = 37/120 (30.83%), Postives = 58/120 (48.33%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPST--ININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFP-----IGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
NGT +I + +PS + + +L + +V SF +G GPIPW + +E++ R MA++ NW +F V + +FP IG Y F I+ + I Y PE E+I
Sbjct: 374 NGT-AIIDSASPSEGISTVKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASFLVGL-LFPILSKKIGAY-VFIIFLILLVVFIVFTYFRVPETKGRTFEDI 490
BLAST of Proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a3b (solute carrier family 2 member 3b [Source:ZFIN;Acc:ZDB-GENE-121031-5]) HSP 1 Score: 72.7886 bits (177), Expect = 6.757e-21 Identity = 64/264 (24.24%), Postives = 129/264 (48.86%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVN--ATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIP--ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLK----RNQNNICDN 973
+S+ P+Y+ EI P +RG T++Q+ + G+ +A ++ + L + + + ++ +F L ES R+LL S N+ DEA + + L+ E +I E + ++ ++ +K+ + + + R+ +++ LQ+ QL GIN +MYY+ +F+ I ++ T + +N + + V+ L+++ GRR L LI L G+ F ++++ ++L+LVD K +N I D+
Sbjct: 139 LSTGLTPMYVGEIAPTALRGAFGTLHQLGVVIGILVAQILGLESLLGSQTLWPLLLALTALPAVIQSIMLIFCL-------ESPRYLLISLNKEDEARQALTSLRGHSDVEDDIREMKDEAMKMSM-----------EKRVSIPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRNA---GITEPVFATIGMGVVNTVFTVVSLFLVERAGRRTLHLIGLTGMTFCVLLVTISLKLVDSEIEKAKLLQNGTAIIDS 381 HSP 2 Score: 47.7506 bits (112), Expect = 6.757e-21 Identity = 37/120 (30.83%), Postives = 58/120 (48.33%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPST--ININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFP-----IGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
NGT +I + +PS + + +L + +V SF +G GPIPW + +E++ R MA++ NW +F V + +FP IG Y F I+ + I Y PE E+I
Sbjct: 374 NGT-AIIDSASPSEGISTVKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASFLVGL-LFPILSKKIGAY-VFIIFLILLVVFIVFTYFRVPETKGRTFEDI 490
BLAST of Proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a1b (solute carrier family 2 member 1b [Source:ZFIN;Acc:ZDB-GENE-090915-1]) HSP 1 Score: 72.4034 bits (176), Expect = 7.409e-21 Identity = 60/266 (22.56%), Postives = 128/266 (48.12%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSY 1003
+S+ P+Y+ E+ P +RG + T++Q+ + G+ +A V + T P +L +PAL + PES R+LL ++N +A V++KL+ ++++ ++ + E + + + + + + + R+ +V+ LQ+ QL GIN + YY+ +F+K ++ ++ T +N + V+ ++++ GRR L L+ L G+ S +++ + + L++ +Y DW+SY
Sbjct: 134 LSTGFVPMYVGEVAPTALRGALGTLHQLGIVVGILMAQVFGMEAIMGNAT-----MWPFLLGFTFIPALVQCCLLPICPESPRFLLINRNEESKAKSVLKKLRGT--TDVSADMQEMKEESRQMMREKKVT-------IPELFRSPLYRQPIVIAIMLQLSQQLSGINAIFYYSTKIFEK---AGVQQPVYATIGAGVVNTAFTVVSLFVVERAGRRSLHLLGLLGMAGSAILMTIAIALLE-KY----------------DWMSY 365 HSP 2 Score: 48.1358 bits (113), Expect = 7.409e-21 Identity = 30/101 (29.70%), Postives = 50/101 (49.50%), Query Frame = 3
Query: 1116 INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPI----GLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
++++ ++ + +V F IG GPIPW + +E++ R + A++ +NW NF V M + G Y F I++ F LC Y PE +EI
Sbjct: 363 MSYMSIVAIFAFVAFFEIGPGPIPWFIVAELFSQGPRPSAFAVAGFSNWTANFIVGMCFQYVEEVCGAY-VFVIFTVFLLCFFIFTYFKVPETKGRTFDEI 462
BLAST of Proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a3b (solute carrier family 2 member 3b [Source:ZFIN;Acc:ZDB-GENE-121031-5]) HSP 1 Score: 70.0922 bits (170), Expect = 4.764e-20 Identity = 63/260 (24.23%), Postives = 128/260 (49.23%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVN--ATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIP--ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDN 973
+S+ P+Y+ EI P +RG T++Q+ + G+ +A ++ + L + + + ++ +F L ES R+LL S N+ DEA + + L+ E +I E + ++ ++ +K+ + + + R+ +++ LQ+ QL GIN +MYY+ +F+ I ++ T + +N + + V+ L+++ GRR L LI L G+ F ++++ ++L+L V L +N I D+
Sbjct: 143 LSTGLTPMYVGEIAPTALRGAFGTLHQLGVVIGILVAQILGLESLLGSQTLWPLLLALTALPAVIQSIMLIFCL-------ESPRYLLISLNKEDEARQALTSLRGHSDVEDDIREMKDEAMKMSM-----------EKRVSIPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRN---AGITEPVFATIGMGVVNTVFTVVSLFLVERAGRRTLHLIGLTGMTFCVLLVTISLKL--VAKLLQNGTAIIDS 379 HSP 2 Score: 47.7506 bits (112), Expect = 4.764e-20 Identity = 37/120 (30.83%), Postives = 58/120 (48.33%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPST--ININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFP-----IGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
NGT +I + +PS + + +L + +V SF +G GPIPW + +E++ R MA++ NW +F V + +FP IG Y F I+ + I Y PE E+I
Sbjct: 372 NGT-AIIDSASPSEGISTVKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASFLVGL-LFPILSKKIGAY-VFIIFLILLVVFIVFTYFRVPETKGRTFEDI 488
BLAST of Proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: phf21b (PHD finger protein 21B [Source:Xenbase;Acc:XB-GENE-969993]) HSP 1 Score: 123.635 bits (309), Expect = 2.696e-47 Identity = 83/286 (29.02%), Postives = 144/286 (50.35%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV-----DVRYLKRN---QNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE P +RGR++TI + +T G F A+VV+ +Y + +L AVPA+ +G L +PES RWL+ K + +A V+ +++ I E ++I + ++ +++ I+ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q ++ ++ +W + F N + + L++K+GRRKL L SL G +L ++A+ L V + + N+ C + +C C +D N G+
Sbjct: 185 IASMTVPVYIAEAAPPHLRGRLVTINTLFITGGQFSAAVVDGAFSYLARDG-----WRYMLGLSAVPAVLQFLGFLFLPESPRWLIQKGQTQKARRVLSQIRG--NQTIDEEYDSIKNS----IDEEEKEGATGGPIIYRMLIYPPTRRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVDDDRLAIWLAAVTAFTNFSFTLLGVWLVEKLGRRKLTLGSLTGTTVALFVLALGFLLSAQVSPPVTFTPGDPSGPNSTCTQY--------SYCNKCMLDPNCGF 451 HSP 2 Score: 86.2705 bits (212), Expect = 2.696e-47 Identity = 46/118 (38.98%), Postives = 63/118 (53.39%), Query Frame = 3
Query: 1062 QTNGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEE 1403
+ G+ Y +C S +W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+ NW N +++T Y T F++Y+ G+ IY PE +EE
Sbjct: 488 KAGGSIWAYNYCPTS---YSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGVNWICNVLISLTFLHTAEYLTYYGAFFLYAGLACVGLIFIYGCLPETKGKKLEE 602
BLAST of Proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: phf21b (PHD finger protein 21B [Source:Xenbase;Acc:XB-GENE-969993]) HSP 1 Score: 124.02 bits (310), Expect = 1.006e-43 Identity = 83/286 (29.02%), Postives = 144/286 (50.35%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV-----DVRYLKRN---QNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE P +RGR++TI + +T G F A+VV+ +Y + +L AVPA+ +G L +PES RWL+ K + +A V+ +++ I E ++I + ++ +++ I+ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q ++ ++ +W + F N + + L++K+GRRKL L SL G +L ++A+ L V + + N+ C + +C C +D N G+
Sbjct: 185 IASMTVPVYIAEAAPPHLRGRLVTINTLFITGGQFSAAVVDGAFSYLAR-----DGWRYMLGLSAVPAVLQFLGFLFLPESPRWLIQKGQTQKARRVLSQIRG--NQTIDEEYDSIKNS----IDEEEKEGATGGPIIYRMLIYPPTRRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVDDDRLAIWLAAVTAFTNFSFTLLGVWLVEKLGRRKLTLGSLTGTTVALFVLALGFLLSAQVSPPVTFTPGDPSGPNSTCTQY--------SYCNKCMLDPNCGF 451 HSP 2 Score: 73.9442 bits (180), Expect = 1.006e-43 Identity = 43/101 (42.57%), Postives = 58/101 (57.43%), Query Frame = 3
Query: 1062 QTNGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFWIYSAFTL-CGIALI 1361
+ G+ Y +C S +W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+ NW N +++T Y T+ Y AF L G+A +
Sbjct: 488 KAGGSIWAYNYCPTS---YSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGVNWICNVLISLTFLHTAEYLTY--YGAFFLYAGLARL 583
BLAST of Proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10 [Source:NCBI gene;Acc:780388]) HSP 1 Score: 77.411 bits (189), Expect = 1.788e-14 Identity = 43/101 (42.57%), Postives = 57/101 (56.44%), Query Frame = 3
Query: 1116 INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMT----VFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+NWI LL M+ +V +F+IG GP+ W+V SEIYPA R A + NW N +T+T + IGL TF +Y L IA IY PE ++EEI
Sbjct: 427 LNWITLLSMMAFVSAFSIGFGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIAFIYFFIPETKGQSLEEI 527
BLAST of Proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10 [Source:NCBI gene;Acc:780388]) HSP 1 Score: 77.411 bits (189), Expect = 1.805e-14 Identity = 43/101 (42.57%), Postives = 57/101 (56.44%), Query Frame = 3
Query: 1116 INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMT----VFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+NWI LL M+ +V +F+IG GP+ W+V SEIYPA R A + NW N +T+T + IGL TF +Y L IA IY PE ++EEI
Sbjct: 417 LNWITLLSMMAFVSAFSIGFGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIAFIYFFIPETKGQSLEEI 517
BLAST of Proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10 [Source:NCBI gene;Acc:780388]) HSP 1 Score: 77.411 bits (189), Expect = 1.818e-14 Identity = 43/101 (42.57%), Postives = 57/101 (56.44%), Query Frame = 3
Query: 1116 INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMT----VFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+NWI LL M+ +V +F+IG GP+ W+V SEIYPA R A + NW N +T+T + IGL TF +Y L IA IY PE ++EEI
Sbjct: 417 LNWITLLSMMAFVSAFSIGFGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIAFIYFFIPETKGQSLEEI 517
BLAST of Proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a13 (solute carrier family 2 (facilitated glucose transporter), member 13 [Source:MGI Symbol;Acc:MGI:2146030]) HSP 1 Score: 140.584 bits (353), Expect = 1.548e-53 Identity = 89/286 (31.12%), Postives = 146/286 (51.05%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQL---VDVRYLKR-----NQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RGR++TI + +T G F ASVV+ +Y +L A+PA+ +G L +PES RWL+ K + +A ++ +++ I E ++I + E++ I+CR+L R+ LV+GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +L+I+A+ L V R R +QN C + C++ C +D + G+
Sbjct: 176 IASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQK-----DGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG--NQTIDEEYDSIRNSIEEEEKEATAAGP----IICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPRVTFRPTTPSDQNTTCTGYSYCNE--------CMLDPDCGF 442 HSP 2 Score: 89.7373 bits (221), Expect = 1.548e-53 Identity = 48/119 (40.34%), Postives = 65/119 (54.62%), Query Frame = 3
Query: 1062 QTNGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+ G Y FC P+ + W L+G++LY++ FA GMGP+PW V SEIYP W RST A S NW FN V++T Y T F++Y+ F G+ +Y PE +EEI
Sbjct: 479 KAEGAHWAYSFC-PTPYS--WTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEI 594
BLAST of Proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a2 (solute carrier family 2 (facilitated glucose transporter), member 2 [Source:MGI Symbol;Acc:MGI:1095438]) HSP 1 Score: 83.1889 bits (204), Expect = 1.505e-16 Identity = 69/244 (28.28%), Postives = 121/244 (49.59%), Query Frame = 2
Query: 215 STCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPES-----NITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD 931
S P+YI EI P +RG + T++Q+ L G+ ++ + + + I+L AVPAL + +L PES R+L K ++E + + LK++ + +I E + EA+ ++K + ++ D R+ +++ L M Q GING+ YY+ S+FQ T I ++ T + IN+I + V+ L++K GRR L L + G+ F + ++V L L+D
Sbjct: 168 SGLVPMYIGEIAPTTLRGALGTLHQLALVTGILISQIAGLSFILGNQDHWH-----ILLGLSAVPALLQCLLLLFCPESPRYLYIK--LEEEVRAKKSLKRLRGTEDVTKDINEMKKEKEEAST-----------EQKVSVIQLFTDANYRQPILVALMLHMAQQFSGINGIFYYSTSIFQ---TAGISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLD 390
BLAST of Proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a1 (solute carrier family 2 (facilitated glucose transporter), member 1 [Source:MGI Symbol;Acc:MGI:95755]) HSP 1 Score: 73.1738 bits (178), Expect = 2.328e-13 Identity = 59/242 (24.38%), Postives = 122/242 (50.41%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD 931
+++ P+Y+ E++P +RG + T++Q+ + G+ +A V + D P + +I I PAL I + PES R+LL ++N + A V++KL+ +++T ++ + E + + + + + R+ +++ LQ+ QL GIN + YY+ S+F+K ++ ++ T +N + V+ ++++ GRR L LI L G+ V++ + L L++
Sbjct: 135 LTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLD-SIMGNADLWPLLLSVIFI----PALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGT--ADVTRDLQEMKEEGRQMMREKKVT-------ILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK---AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLE 359
BLAST of Proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a12 (solute carrier family 2 (facilitated glucose transporter), member 12 [Source:MGI Symbol;Acc:MGI:3052471]) HSP 1 Score: 71.2478 bits (173), Expect = 1.236e-12 Identity = 35/100 (35.00%), Postives = 59/100 (59.00%), Query Frame = 3
Query: 1119 NWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFP----IGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
W+ L +++YV +F+IG+GP+PW+V SEI+P R MAL+++ NW N +++T IGL +IY+ +L +A + PE ++E+I
Sbjct: 466 KWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFLTVTDLIGLSWVCFIYTIMSLASLAFVVLFIPETKGCSLEQI 565
BLAST of Proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10 [Source:MGI Symbol;Acc:MGI:2156687]) HSP 1 Score: 67.0106 bits (162), Expect = 2.342e-11 Identity = 36/99 (36.36%), Postives = 56/99 (56.57%), Query Frame = 3
Query: 1122 WILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMT----VFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
W L+ M++YV +F++G GP+ W+V SEIYPA R A ++ NW N ++++ + IGL TF +Y + G+A IY PE ++ EI
Sbjct: 406 WSALVCMMVYVSAFSVGFGPVTWLVLSEIYPAEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLAWTFLLYGLTAVLGLAFIYLLVPETKGQSLAEI 504
BLAST of Proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q3UHK1|MYCT_MOUSE (Proton myo-inositol cotransporter OS=Mus musculus OX=10090 GN=Slc2a13 PE=1 SV=2) HSP 1 Score: 140.584 bits (353), Expect = 9.315e-53 Identity = 89/286 (31.12%), Postives = 146/286 (51.05%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQL---VDVRYLKR-----NQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RGR++TI + +T G F ASVV+ +Y +L A+PA+ +G L +PES RWL+ K + +A ++ +++ I E ++I + E++ I+CR+L R+ LV+GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +L+I+A+ L V R R +QN C + C++ C +D + G+
Sbjct: 176 IASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQK-----DGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG--NQTIDEEYDSIRNSIEEEEKEATAAGP----IICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPRVTFRPTTPSDQNTTCTGYSYCNE--------CMLDPDCGF 442 HSP 2 Score: 89.7373 bits (221), Expect = 9.315e-53 Identity = 48/119 (40.34%), Postives = 65/119 (54.62%), Query Frame = 3
Query: 1062 QTNGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+ G Y FC P+ + W L+G++LY++ FA GMGP+PW V SEIYP W RST A S NW FN V++T Y T F++Y+ F G+ +Y PE +EEI
Sbjct: 479 KAEGAHWAYSFC-PTPYS--WTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEI 594
BLAST of Proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q9ZQP6|INT3_ARATH (Probable inositol transporter 3 OS=Arabidopsis thaliana OX=3702 GN=INT3 PE=2 SV=1) HSP 1 Score: 109.768 bits (273), Expect = 1.372e-34 Identity = 81/301 (26.91%), Postives = 141/301 (46.84%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDK--------IARKTLVMGCSLQMLAQLIGINGLMYYANSLFQ--KYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD---VRYLKRNQNNICDN--------FLA---------CDDWVSYHCEYCQ 1021
++S PLYI+E++P IRG +++ + +T G FL+ ++N + +P T +L A+PA+ MLT+PES RWL +R E+ +++ ++ + ++EA + ++ + + I+ DK + R L G ++Q+ Q +GIN +MYY+ ++ Q Y +N + L + + +N + S V+ +D+ GRRKL +IS+FGII LVI+A + KR+ N N F A C + Y C +C
Sbjct: 135 MASMTSPLYISEMSPARIRGALVSTNGLLITGGQFLSYLINLAFVH------TPGTWRWMLGVSAIPAIIQFCLMLTLPESPRWLYRNDRKAESRDILERI----------YPAEMVEAEIAALKESVRAETADEDIIGHTFSDKLRGALSNPVVRHGLAAGITVQVAQQFVGINTVMYYSPTILQFAGYASNKTAMALAL--ITSGLNAVGSVVSMMFVDRYGRRKLMIISMFGIITCLVILAAVFNEASNHAPKIDKRDSRNFAKNATCPAFAPFTASRSPPSNWNCMKCLQYDCGFCS 417 HSP 2 Score: 59.6918 bits (143), Expect = 1.372e-34 Identity = 38/123 (30.89%), Postives = 58/123 (47.15%), Query Frame = 3
Query: 1062 QTNGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVF----PIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 1418
+ G + C PS I+ LG LY+I +A GMG +PW+V SEIYP R ++ +NW N V+ T +G TF +++ + G+ I+ PE EE+ +L
Sbjct: 440 HSKGRTFFKDGC-PSKFGYLAIVFLG--LYIIVYAPGMGTVPWIVNSEIYPLRYRGLAGGIAAVSNWMSNLVVSETFLTLTNAVGSSGTFLLFAGSSAVGLFFIWLLVPETKGLQFEEVEKLL 559
BLAST of Proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q96QE2|MYCT_HUMAN (Proton myo-inositol cotransporter OS=Homo sapiens OX=9606 GN=SLC2A13 PE=1 SV=3) HSP 1 Score: 137.502 bits (345), Expect = 2.146e-33 Identity = 84/286 (29.37%), Postives = 145/286 (50.70%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQL---VDVRYLKR-----NQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RGR++TI + +T G F ASVV+ +Y +L AVPA+ G L +PES RWL+ K + +A ++ +++ + ++ ++ E+ +++ ++CR+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +L+I+A+ L V R + QN C + C++ C +D + G+
Sbjct: 187 IASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQK-----DGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRG------NQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNE--------CMLDPDCGF 453 HSP 2 Score: 92.0485 bits (227), Expect = 1.980e-18 Identity = 50/111 (45.05%), Postives = 64/111 (57.66%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y FC P+ + W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+ NW FN V++T Y T F++Y+ F G+ IY PE +EEI
Sbjct: 498 YNFC-PTPYS--WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605
BLAST of Proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q921A2|MYCT_RAT (Proton myo-inositol cotransporter OS=Rattus norvegicus OX=10116 GN=Slc2a13 PE=1 SV=2) HSP 1 Score: 137.117 bits (344), Expect = 2.413e-33 Identity = 88/286 (30.77%), Postives = 143/286 (50.00%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQL---VDVRYLKR-----NQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RGR++TI + +T G F ASVV+ +Y +L A+PA+ +G L +PES RWL+ K + +A ++ +++ I E ++I + E++ I+CR+L R+ L +GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +L I+A+ L V R R QN C + C++ C +D + G+
Sbjct: 176 IASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-----WRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG--NQTIDEEYDSIRNSIEEEEKEASAAGP----IICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNE--------CMLDPDCGF 442 HSP 2 Score: 89.3521 bits (220), Expect = 1.382e-17 Identity = 47/111 (42.34%), Postives = 63/111 (56.76%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y FC P+ + W L+G++LY++ FA GMGP+PW V SEIYP W RST A S NW FN V++T Y T F++Y+ F G+ +Y PE +EEI
Sbjct: 487 YSFC-PTPYS--WTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEI 594
BLAST of Proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q8VZR6|INT1_ARATH (Inositol transporter 1 OS=Arabidopsis thaliana OX=3702 GN=INT1 PE=1 SV=1) HSP 1 Score: 110.923 bits (276), Expect = 9.557e-25 Identity = 74/237 (31.22%), Postives = 127/237 (53.59%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNL 919
++S P+YIAE +P +RG +++ + +T G FL+ +VN+ + P T +L VPA+ I ML +PES RWL KNR EAI+V+ + I S + + ++++ A +E++ ++ + K R + G LQ Q GIN +MYY+ ++ Q ++ ++ L+ + ++ +N + V ID GR+KLAL SLFG+I SL+I++V+
Sbjct: 140 VASVTAPVYIAEASPSEVRGGLVSTNVLMITGGQFLSYLVNSAFT------QVPGTWRWMLGVSGVPAVIQFILMLFMPESPRWLFMKNRKAEAIQVLARTYDI--SRLEDEIDHLSAAE------EEEKQRKRTVGYLDVFRSKELRLAFLAGAGLQAFQQFTGINTVMYYSPTIVQMAGFHSNQLALFLSLIVAAMNAAGTVVGIYFIDHCGRKKLALSSLFGVIISLLILSVSF 362 HSP 2 Score: 63.929 bits (154), Expect = 1.617e-9 Identity = 35/103 (33.98%), Postives = 48/103 (46.60%), Query Frame = 3
Query: 1119 NWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPI----GLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHV 1415
W+ +LG+ LY++ FA GMGP+PW V SEIYP R +S T NW N V T I G TF I + + + + PE E+ +
Sbjct: 376 GWLAVLGLALYIVFFAPGMGPVPWTVNSEIYPQQYRGICGGMSATVNWISNLIVAQTFLTIAEAAGTGMTFLILAGIAVLAVIFVIVFVPETQGLTFSEVEQI 478
BLAST of Proton myo-inositol cotransporter vs. TrEMBL
Match: A0A0H3YJX4 (Slc2a-9 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=slc2a-9 PE=2 SV=1) HSP 1 Score: 505.753 bits (1301), Expect = 0.000e+0 Identity = 271/286 (94.76%), Postives = 274/286 (95.80%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSYHCEYCQIDENSGYTCVNYGAN 1066
ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPT S T PIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIEEDLQEQKEQKKFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGII S VIIAVNLQLVDVRYLKRNQNN C NFL+CDD ++ CEYCQIDENSGYTCVNYGAN
Sbjct: 134 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIEEDLQEQKEQKKFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIISSSVIIAVNLQLVDVRYLKRNQNNNCRNFLSCDDCINNICEYCQIDENSGYTCVNYGAN 419 HSP 2 Score: 199.134 bits (505), Expect = 0.000e+0 Identity = 98/117 (83.76%), Postives = 101/117 (86.32%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 1418
G IY F N T NINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTA W N +VTMTVF LYETFWIYSAFT+CGIALIY+NFPEMNQANMEEILHVL
Sbjct: 423 KGNYPIYNFDNHCTNNINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTAKWLCNLTVTMTVFTRRLYETFWIYSAFTICGIALIYKNFPEMNQANMEEILHVL 539 HSP 3 Score: 139.043 bits (349), Expect = 7.892e-32 Identity = 67/74 (90.54%), Postives = 70/74 (94.59%), Query Frame = 3
Query: 3 EFIVILNFIFICSFNLMNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTETVPNVYGIFVFLLLA 224
EFIVILNFIFICSFNLMNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVT TVP+VYGIF ++A
Sbjct: 1 EFIVILNFIFICSFNLMNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFMVA 74
BLAST of Proton myo-inositol cotransporter vs. TrEMBL
Match: A0A0H3YIU7 (Slc2a-10 OS=Schmidtea mediterranea OX=79327 GN=slc2a-10 PE=2 SV=1) HSP 1 Score: 214.157 bits (544), Expect = 3.835e-59 Identity = 114/275 (41.45%), Postives = 174/275 (63.27%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRN--QNNICDNFLACDDWV-SYHCEYCQI 1024
IS+ CCP+YIAE++P IRGR+I IYQI +T G+F A++V+A+ Y + +L A+P+ IGMLTVPESYRWLLSKN++DEA ++ Q+PE ITE+++ I+ AN I+ ++E + + ++ +I + +AR++L++GC LQML Q+IGIN +MYY + + +I LW + L+ F N I SF+ + LIDKIGRRKL++ SL ++ SL+ IA+ Q++ + K NN C + C++ V S C +C I
Sbjct: 130 ISAACCPVYIAEVSPHQIRGRLIVIYQISITGGMFFAALVDASFFYLGK-----EGWRYMLGGAAIPSFIEFIGMLTVPESYRWLLSKNKVDEARTIIVNQGQVPEERITEYIDEIVRANQQIQMQVKEHEGNSRSLIFQIFRNDVARRSLLIGCGLQMLQQIIGINTIMYYTALVIRMSGVKDISTILWLSALVAFFNFIPSFIGFILIDKIGRRKLSISSLCCVLLSLITIAITFQVLVSQSEKVTYPSNNYCGKKINCEECVTSSACGFCYI 399 HSP 2 Score: 128.642 bits (322), Expect = 3.666e-28 Identity = 62/115 (53.91%), Postives = 81/115 (70.43%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVF----PIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 1418
Y+FC +W++++G+ILY+ISF+IGMGPIPW +TSEIYP WCRSTNMALST+ NW FN V++T I Y TFW+YS+F GI IY+ PE NQ ++EEI +L
Sbjct: 444 YDFC---VSKYSWVIIVGLILYLISFSIGMGPIPWAITSEIYPLWCRSTNMALSTSTNWVFNLIVSLTFLSLTEAITKYGTFWLYSSFAFFGILFIYKFVPETNQRSLEEINDLL 555
BLAST of Proton myo-inositol cotransporter vs. TrEMBL
Match: L7MH30 (Putative proton myo-inositol cotransporter (Fragment) OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1) HSP 1 Score: 152.14 bits (383), Expect = 1.241e-50 Identity = 98/298 (32.89%), Postives = 151/298 (50.67%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITP------------------AVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRN-----QNNICDNFLACDDWVSYH-CEYCQIDE 1030
++S P+YIAE++P +RG ++TI Q+ +T G F+ASV + ++S T+ + M + P VP+L L+G L +PES RWL SK EAIEV+R+ + P++NI E EA D + +E +L ++L D R L++GC+L M Q+ GIN +MYY ++ Q ++ +W +F+N SF+ L+++IGRR L L+SL G+I SL ++A QL D+ + IC NF C C YC I +
Sbjct: 138 LASMTVPVYIAEVSPAELRGFLVTINQVFITGGQFIASVADGL--FSSDTENGWRYMLALAGVPSLIQLLGFLXWRYMLALAGVPSLIQLLGFLGMPESPRWLASKGAYQEAIEVLRRFRG-PDANI----EPEFEALKATCIDNDQDEEHSGPVLIQVLRDGPLRLALIVGCALMMFQQIAGINTVMYYGATIIQMSGVHDASKAIWLAAATSFVNFACSFIGMALVERIGRRLLTLLSLAGVIASLSVLAGGFQLADMESPSVGPIVVPSSGICGNFSTCASCTGVSGCGYCYIPD 428 HSP 2 Score: 78.9518 bits (193), Expect = 1.241e-50 Identity = 44/111 (39.64%), Postives = 66/111 (59.46%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVF----PIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y +C PS +W+ +LG++LY+ FA G+G +PW + SEIYP W RST +++T+ NW FN V+MT I Y TFW+Y+ +L G + PE ++EE+
Sbjct: 464 YNWC-PS--RYSWMTILGLVLYLFFFAPGLGAMPWTINSEIYPLWARSTCFSVATSFNWAFNLLVSMTFLTLTEAITKYGTFWLYAGLSLLGWFFFFLFLPETKGKSLEEV 571
BLAST of Proton myo-inositol cotransporter vs. TrEMBL
Match: R7U3K5 (MFS domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_175747 PE=3 SV=1) HSP 1 Score: 144.436 bits (363), Expect = 1.295e-50 Identity = 86/287 (29.97%), Postives = 145/287 (50.52%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIP--ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRY----LKRNQNNI---CDNFLACDDWVSY-HCEYCQIDENSG 1039
+SS P+YIAE P +RGR++T+ I +T G +AS+++ +Y D+ +L VPA + + +PES RWL+ K RI +A EV++K++ + + E + EA+ E R L R+ L++GC LQ+ Q+ GIN +MYY+ ++ + + + +W + L +N I +FV L++++GRR+L L S+ G+ SL ++A+ Q+ +R N+ CD F CD VS C +C + +SG
Sbjct: 145 LSSMAIPMYIAENAPCHLRGRLVTMNNIFITGGQLIASLIDGAFSY----DKI-NGWRYMLGLAGVPAAIQFVAFIFMPESARWLVGKGRISQAGEVLKKIRGTENIDHELEEIRSSYAEAHACTSEAEGSSST-----FVRALKTPHVRRALIVGCGLQLFQQICGINTVMYYSATIIKMSGVKDASLAIWLSSLTAGVNFIFTFVGLYLVERMGRRRLTLFSVVGVTISLAVLAIGFQITAIRSPRVTFDEGMNSTSYDCDRFSTCDGCVSSPDCGFCFLPSSSG 421 HSP 2 Score: 86.6557 bits (213), Expect = 1.295e-50 Identity = 44/111 (39.64%), Postives = 63/111 (56.76%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVF----PIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y++C PS++ W+ G++LY+ FA GMGP+PW + SEIYP W RST +LST NW N V+MT + Y FW+YS +L G + PE ++E +
Sbjct: 460 YDYC-PSSMA--WMSTFGLVLYLAFFAPGMGPMPWTINSEIYPLWARSTGNSLSTATNWIANLVVSMTFLSLLEALTKYGAFWLYSVLSLLGTIFFFALLPETRGLSLEHM 567
BLAST of Proton myo-inositol cotransporter vs. TrEMBL
Match: L7MDM9 (Putative proton myo-inositol cotransporter (Fragment) OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1) HSP 1 Score: 151.754 bits (382), Expect = 1.477e-50 Identity = 98/298 (32.89%), Postives = 152/298 (51.01%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPA------------------VPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRN-----QNNICDNFLACDDWVSYH-CEYCQIDE 1030
++S P+YIAE++P +RG ++TI Q+ +T G F+ASV + ++S T+ + M + P+ VP+L L+G L +PES RWL SK EAIEV+R+ + P++NI E EA D + +E +L ++L D R L++GC+L M Q+ GIN +MYY ++ Q ++ +W +F+N SF+ L+++IGRR L L+SL G+I SL ++A QL D+ + IC NF C C YC I +
Sbjct: 129 LASMTVPVYIAEVSPAELRGFLVTINQVFITGGQFIASVADGL--FSSDTENGWRYMLALAGVPSLIQLLGFLXWRYMLALAGVPSLIQLLGFLGMPESPRWLASKGAYQEAIEVLRRFRG-PDANI----EPEFEALKATCIDNDQDEEHSGPVLIQVLRDGPLRLALIVGCALMMFQQIAGINTVMYYGATIIQMSGVHDASKAIWLAAATSFVNFACSFIGMALVERIGRRLLTLLSLAGVIASLSVLAGGFQLADMESPSVGPIVVPSSGICGNFSTCASCTGVSGCGYCYIPD 419 HSP 2 Score: 78.5666 bits (192), Expect = 1.477e-50 Identity = 44/111 (39.64%), Postives = 66/111 (59.46%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVF----PIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y +C PS +W+ +LG++LY+ FA G+G +PW + SEIYP W RST +++T+ NW FN V+MT I Y TFW+Y+ +L G + PE ++EE+
Sbjct: 455 YNWC-PS--RYSWMTILGLVLYLFFFAPGLGAMPWTINSEIYPLWARSTCFSVATSFNWAFNLLVSMTFLTLTEAITKYGTFWLYAGLSLLGWFFFFLFLPETKGKSLEEV 562
BLAST of Proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: SLC2A13 (solute carrier family 2 member 13 [Source:NCBI gene;Acc:103031966]) HSP 1 Score: 132.109 bits (331), Expect = 1.545e-32 Identity = 88/279 (31.54%), Postives = 145/279 (51.97%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSY-HCEYCQIDENSGY 1042
ISS P+YIAE +P +RG+++T+ + +T G F+AS+++ +Y +L AVPAL G L +PES RWL+ K +A V+ +++ NI E E+I + E+ ++ IL R+L AR+ L++GC LQM QL GIN +MYY+ ++ Q + K+ +W + L N + + + L++K+GRR+L+L S+ G SL ++A L+ ++ + D LA Y CE C +D + G+
Sbjct: 199 ISSMTVPVYIAEASPPHLRGQLVTVNTLFITAGQFVASLIDGAFSYVQHGG-----WRYMLGLSAVPALVQFFGFLFLPESPRWLIQKGLTQKARRVLSQIRG--NQNIDEEYESIKSS----IEEEEKDCGGDGPILWRMLTYPPARRALIVGCGLQMFQQLSGINTVMYYSATILQMSGVRDDKLAIWLSSLTALTNFLFTLLGVWLVEKVGRRRLSLGSIIGTSVSLCLLAFGF-LLSAQHSPPVTIHPTDPSLANSSCTRYLSCEPCMLDPSCGF 465 HSP 2 Score: 93.5893 bits (231), Expect = 7.609e-20 Identity = 50/111 (45.05%), Postives = 65/111 (58.56%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y FC S +W++LLG+ILY+ FA G+GP+PW V SEIYP W RST A S NW FN V++T + Y T F++YS+ +L G IY PE +EEI
Sbjct: 509 YNFCPTS---YSWVVLLGLILYLAFFAPGLGPMPWTVNSEIYPLWARSTGNACSAGVNWTFNVLVSLTFLHLAQYLTYYGAFFLYSSLSLLGFFFIYGCLPETKGRRLEEI 616
BLAST of Proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a13b (solute carrier family 2 member 13b [Source:ZFIN;Acc:ZDB-GENE-090812-1]) HSP 1 Score: 126.716 bits (317), Expect = 4.780e-31 Identity = 91/285 (31.93%), Postives = 141/285 (49.47%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILE--ANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV-----DVRYLKRNQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RG+++TI + +T G F+ASVV+ +Y S +L AVPA+ IG L +PES RWLL K R +A EV+ ++ EN+ E N+ + +E++ +L RIL AR+ LV+GC LQM QL GIN +MYY+ ++ Q + K+ +W + F N + + V L++ + KL L+ G SL ++AV L V + N C ++ CE C +D G+
Sbjct: 82 IASMTVPVYIAEVSPSHLRGQLVTINTLFITGGQFIASVVDGAFSYLSHGGWR-----YMLGLSAVPAVLQFIGFLFLPESPRWLLQKGRSQQAREVLTHIRA---------TENVDEEFNNIKNIIEEEEKESGGGLVLWRILTSAPARRALVVGCGLQMFQQLSGINTVMYYSATILQMAGVRDDKMAIWLSAATAFTNFLFTLVGVWLVEH--KTKLYLLLSSGTTVSLSVLAVGFLLSAQASPPVTIHPTSLNTTCSHY--------GFCENCMLDPACGF 342 HSP 2 Score: 81.6481 bits (200), Expect = 3.480e-16 Identity = 42/100 (42.00%), Postives = 57/100 (57.00%), Query Frame = 3
Query: 1119 NWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
+WI++LG++LY+ FA GMGP+PW V SEIYP W RST A S NW N V++T + Y T F++YS L G + PE +E+I
Sbjct: 388 SWIVMLGLLLYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAEYLTYYGAFFLYSGLALLGFFFVLGCLPETKGLMLEDI 487
BLAST of Proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a3b (solute carrier family 2, facilitated glucose transporter member 3-like [Source:NCBI gene;Acc:103028878]) HSP 1 Score: 63.929 bits (154), Expect = 3.732e-20 Identity = 60/261 (22.99%), Postives = 124/261 (47.51%), Query Frame = 2
Query: 227 PLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEA---IEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVS 1000
P+Y+ E+ P RG T++Q+ + G+ +A ++ + S P++L A+PA+ + ++ ES R+LL + +E I V+ + ++ E +I E E EA+ L +E + + + I R+ +++ + + Q GIN + YY+ +F+ ++ + ++ T IN + + V+ L+++ GRR L + L G+ +++ + LQLV Q ++C + C+ V+
Sbjct: 94 PMYVGELAPTAQRGAFGTLHQLAIVIGILIAQILGLEVLLGSE-----YLWPLLLGLTALPAVLQSVMLIFCSESPRYLLINLKQEEEARRILVLLRGQEDVEDDIREMKE---EADKLNQEQKVS--------IPELFRNPIYRQPIIIAIVMNVSQQFSGINAVFYYSTQIFK---SSGVSEPIYATIGTGIINTVFTVVSLFLVERAGRRTLQMFGLGGMAICALVMTIVLQLVLDPCAP--QEDLCAAPVVCNGTVA 333 HSP 2 Score: 53.9138 bits (128), Expect = 3.732e-20 Identity = 27/78 (34.62%), Postives = 44/78 (56.41%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPI 1301
NGT ++ + T I+++ +L + +V SF IG GPIPW + +E++ R +A+ +NW NF V M FP+
Sbjct: 329 NGTVAVTSDASSKTPVISYVAILAVFGFVASFEIGPGPIPWFIATELFAQDARPAAVAVGGCSNWISNFLVAM-FFPM 405
BLAST of Proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a3b (solute carrier family 2, facilitated glucose transporter member 3-like [Source:NCBI gene;Acc:103028878]) HSP 1 Score: 63.1586 bits (152), Expect = 6.454e-20 Identity = 60/261 (22.99%), Postives = 124/261 (47.51%), Query Frame = 2
Query: 227 PLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEA---IEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVS 1000
P+Y+ E+ P RG T++Q+ + G+ +A ++ + S P++L A+PA+ + ++ ES R+LL + +E I V+ + ++ E +I E E EA+ L +E + + + I R+ +++ + + Q GIN + YY+ +F+ ++ + ++ T IN + + V+ L+++ GRR L + L G+ +++ + LQLV Q ++C + C+ V+
Sbjct: 146 PMYVGELAPTAQRGAFGTLHQLAIVIGILIAQILGLEVLLGSE-----YLWPLLLGLTALPAVLQSVMLIFCSESPRYLLINLKQEEEARRILVLLRGQEDVEDDIREMKE---EADKLNQEQKVS--------IPELFRNPIYRQPIIIAIVMNVSQQFSGINAVFYYSTQIFK---SSGVSEPIYATIGTGIINTVFTVVSLFLVERAGRRTLQMFGLGGMAICALVMTIVLQLVLDPCAP--QEDLCAAPVVCNGTVA 385 HSP 2 Score: 53.9138 bits (128), Expect = 6.454e-20 Identity = 27/78 (34.62%), Postives = 44/78 (56.41%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPI 1301
NGT ++ + T I+++ +L + +V SF IG GPIPW + +E++ R +A+ +NW NF V M FP+
Sbjct: 381 NGTVAVTSDASSKTPVISYVAILAVFGFVASFEIGPGPIPWFIATELFAQDARPAAVAVGGCSNWISNFLVAM-FFPM 457
BLAST of Proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a1b (solute carrier family 2, facilitated glucose transporter member 1-like [Source:NCBI gene;Acc:103036684]) HSP 1 Score: 79.337 bits (194), Expect = 2.200e-15 Identity = 61/242 (25.21%), Postives = 124/242 (51.24%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD 931
+S+ P+Y+ E+ P +RG + T++Q+ + G+ +A V + + T P +L +PAL I + PES R+LL ++N +A ++KL+ S+++ ++ + E + + + + + +L I R+ LV+ LQ+ QL GIN + Y++ ++F+K ++ ++ T +N + V+ L+++ GRR L LI L G+ S +++ + L L++
Sbjct: 135 LSTGFVPMYVGEVAPTALRGALGTLHQLGIVVGILVAQVFGLDVIMGNAT-----MWPFLLGFTFIPALAQCILLPMCPESPRYLLINRNEESKAKAALKKLRGT--SDVSADMQEMKEESRQMMREKKVT-------IPELLRSSIYRQPLVIAVMLQLSQQLSGINAVFYFSTAIFEK---AGVEQPVYATIGAGVVNTAFTVVSLFLVERAGRRSLHLIGLLGMAGSAILMTIALALLN 359
BLAST of Proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002434.1 (pep scaffold:Pmarinus_7.0:GL479978:1522:11010:-1 gene:ENSPMAG00000002223.1 transcript:ENSPMAT00000002434.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 75.485 bits (184), Expect = 3.121e-16 Identity = 35/99 (35.35%), Postives = 58/99 (58.59%), Query Frame = 2
Query: 614 FILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIA 910
++L +++ R+ LV+GC LQM QL GIN +MYY+ ++ Q + +W F N I S + L++++GRR+L+LIS+ G I SL ++
Sbjct: 2 WVLWKMIKHPPTRRALVVGCGLQMFQQLAGINTVMYYSATILQMAGVADDSTAIWLASATAFTNFIFSALGVWLVERVGRRQLSLISMAGAIVSLALLG 100
BLAST of Proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Match: SLC2A9 (solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446]) HSP 1 Score: 63.5438 bits (153), Expect = 4.111e-11 Identity = 66/246 (26.83%), Postives = 119/246 (48.37%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRW-LLSKNRIDEAIEVVRKL--KQIPESNITEF-VENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLF-QKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFG---IIFSLVIIAVNLQ 922
IS + P+Y+AEI+PK +RG + I + G+F V+N + S I+ VP L L + +PES R+ LL + + A + +++L +Q + + E E I +A++ + L +L ++ R ++ QL G+N + +YA+S+F Q + I Y+ + T ++++ ++ I+K+GRR L LI FG +IF ++ +A+NLQ
Sbjct: 97 ISLSVLPMYLAEISPKNLRGSTGQVSAIFICLGVFTGQVLNLKEVLGQESHWS-----ILFGILVVPPLVQLATLPFMPESPRYLLLERQDVKAAEKALQRLLGRQDVQREMVEIQAEGIAQAHISVMS------------LWGLLRERAVRWQVITVAITMACYQLCGVNAIWFYASSIFRQAGIDPAITPYIIISTGGT--EVLAALLSGLAIEKLGRRSL-LIVGFGAMAVIFGVLTVALNLQ 322
BLAST of Proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006105.1 (pep scaffold:Pmarinus_7.0:GL483550:10411:12132:-1 gene:ENSPMAG00000005515.1 transcript:ENSPMAT00000006105.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.5286 bits (127), Expect = 8.530e-9 Identity = 32/111 (28.83%), Postives = 49/111 (44.14%), Query Frame = 3
Query: 1095 CNPSTININWILLL---GMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVT----MTVFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
ST ++ W+ L G+ F++G GPIPW+V SE++P R + NW F VT V +G FW +++ G L PE ++E+I
Sbjct: 47 AGASTGSLGWLALASMAGLHRRCGRFSLGWGPIPWIVMSEVFPVRWRGVASGVCVAVNWISAFVVTKPTSAAVEWLGFPGAFWFFASVCAAGFVLTIVALPETKGRSLEQI 157
BLAST of Proton myo-inositol cotransporter vs. Ensembl Yeast
Match: ITR1 (Myo-inositol transporter; member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p; relative distribution to the vacuole increases upon DNA replication stress; ITR1 has a paralog, ITR2, that arose from the whole genome duplication [Source:SGD;Acc:S000002905]) HSP 1 Score: 90.5077 bits (223), Expect = 7.495e-20 Identity = 70/245 (28.57%), Postives = 118/245 (48.16%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVV-RKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRY 940
I S PL+I+EI PK+IRGR+ I + LT G +A A LNY + R I++ +P + +P++ R+ + K + A EV+ R E I VE ++ N I +K + + + L++GC LQ + Q G N LMY++ ++F+ T K + +++ N I + VA+ IDKIGRR + LI L G+ +LV+ ++ + +++
Sbjct: 195 IGSLIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWR------ILVGLSLIPTAVQFTCLCFLPDTPRYYVMKGDLARATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPEKVWNTIKELHTVPSNL--RALIIGCGLQAIQQFTGWNSLMYFSGTIFE---TVGFKNSSAVSIIVSGTNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKF 428
BLAST of Proton myo-inositol cotransporter vs. Ensembl Yeast
Match: HXT13 (Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication [Source:SGD;Acc:S000000795]) HSP 1 Score: 87.8113 bits (216), Expect = 6.103e-19 Identity = 71/237 (29.96%), Postives = 123/237 (51.90%), Query Frame = 2
Query: 215 STCCPLYIAEITPKVIRGRIITIYQICLTFGLFLA-SVVNATLNYASPTD-RSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQI-PESNITEFVENILEANVLIXXXXXXXXXXXXF-ILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKY-VTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIA 910
S CP+ ++EI P +RG ++++YQ+ +TFG+FL V T Y + R P + + AL ++IGML VPES R+L+ R +EA + K+ ++ PE + + A VL + +L E ++ F + ++L + L+ G +Q QL G N +Y ++F+ +T+ + + +L +N S+ +A ++DKIGRRK L G++ +VI A
Sbjct: 178 SVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLW------ALIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVL------QRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSI----VLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFA 398
BLAST of Proton myo-inositol cotransporter vs. Ensembl Yeast
Match: HXT5 (Hexose transporter with moderate affinity for glucose; induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs; HXT5 has a paralog, HXT3, that arose from the whole genome duplication [Source:SGD;Acc:S000001138]) HSP 1 Score: 87.8113 bits (216), Expect = 7.090e-19 Identity = 68/236 (28.81%), Postives = 119/236 (50.42%), Query Frame = 2
Query: 227 PLYIAEITPKVIRGRIITIYQICLTFGLFLASVVN-ATLNYASPTD-RSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESN--ITEFVENI---LEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKY-VTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIA 910
P+ I+E++PK +RG +++ YQ+ +TFG+FL N T NY++ R P + ++F+++GM VPES R+L+ +I+EA + + + E + +T +EN +EA L + K ++ R+TL MG +Q L QL G N YY ++FQ + ++ + + +L +N +S+F + +D+ GRR L G+I V+ A
Sbjct: 210 PMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAW------SIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGK--------PQMFRRTL-MGMMIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAI----VLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYA 426
BLAST of Proton myo-inositol cotransporter vs. Ensembl Yeast
Match: ITR2 (Myo-inositol transporter; member of the sugar transporter superfamily; expressed constitutively; ITR2 has a paralog, ITR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005463]) HSP 1 Score: 87.4261 bits (215), Expect = 8.004e-19 Identity = 76/280 (27.14%), Postives = 129/280 (46.07%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDR---SPKTMPIIL------ITPAVPALFLLIGMLTVPE---SYRWLLSKNR-IDEAIEVVRKLKQ-IPESN-ITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSY 1003
I S PL+I+EI PK+IRGR+ I + LT G +A A LN+ R +P +L P P +++ G L + ++ +++ ID+ +E + L Q IP N IT+F + E + + + L++GC LQ + Q G N LMY++ ++F+ T K + +++ N + + +A+ IDKIGRR + LI L G+ +LVI A+ + +++ N D +A D + S+
Sbjct: 218 IGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNF----------------------RALIIGCGLQAIQQFTGWNSLMYFSGTIFE---TVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKF------NGADAVVASDGFSSW 466
BLAST of Proton myo-inositol cotransporter vs. Ensembl Yeast
Match: HXT3 (Low affinity glucose transporter of the major facilitator superfamily; expression is induced in low or high glucose conditions; HXT3 has a paralog, HXT5, that arose from the whole genome duplication [Source:SGD;Acc:S000002753]) HSP 1 Score: 87.0409 bits (214), Expect = 9.514e-19 Identity = 66/233 (28.33%), Postives = 109/233 (46.78%), Query Frame = 2
Query: 227 PLYIAEITPKVIRGRIITIYQICLTFGLFLASVVN-ATLNYASPTD-RSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQI-PESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTF--INLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIA 910
P+ I+E+ PK +RG +++ YQ+ +T G+FL N T NY++ R P + ALF++ GM VPES R+L+ +IDEA + K+ ++ P+ + ++EA+V + F G K +MG +Q L QL G N YY ++F N + + F + F +N S+ + +D+ GRR L G++ V+ A
Sbjct: 186 PMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAW------ALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFT-----GKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVF-----NAVGMSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYA 402
BLAST of Proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO46902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNS4]) HSP 1 Score: 119.783 bits (299), Expect = 4.151e-29 Identity = 91/284 (32.04%), Postives = 143/284 (50.35%), Query Frame = 2
Query: 212 SSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNI-------CDNFLACDDWVSY-HCEYCQIDENSG 1039
+S P+Y+AE P +RG+++T+ + +T G F+ASVV+ Y DR +L AVP++ + G + +PES RWL+SK + EA + K++ + V+ LEA + E+KE+ +L RIL R+ L++GC LQ + QL GIN +MYY+ ++ N K +W + F N + + V L+++IGRRKL L SL G+I SL ++ L K + C N C D V+ +C YC ++ G
Sbjct: 112 ASMTVPIYVAEAAPSSMRGKLVTLNNLFITGGQFIASVVDGIFAY----DRQ-NGWRFMLGLAAVPSIIMFFGCVILPESPRWLISKCKYAEARAALCKIRGRTD------VDRELEA--VRRTCKVERKERSGQVLIRILRFPNTRRALLVGCMLQAIQQLCGINTVMYYSATIILMSGIGNSKTSIWLAAAIAFGNTLFTIVGIFLVERIGRRKLLLGSLAGVILSLFLLGGAFYLAMQHNPKVSTAETINPVFTHCTNQTTCMDCVNVRNCGYCYSTDSDG 382 HSP 2 Score: 77.7962 bits (190), Expect = 2.281e-15 Identity = 37/99 (37.37%), Postives = 55/99 (55.56%), Query Frame = 3
Query: 1122 WILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
W+ LG+++Y+ +FA GMGP+PW + SE+YP W RST A ST NW N ++MT + + T FW+Y + G + PE +EE+
Sbjct: 424 WMAFLGLVIYIATFAPGMGPMPWTLNSEMYPLWARSTGNACSTAVNWICNLVISMTFLSLMGWITRPGAFWLYGCIAVAGWVFFFVFVPETKGKTLEEL 522
BLAST of Proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO32615 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUJ6]) HSP 1 Score: 70.0922 bits (170), Expect = 5.478e-13 Identity = 40/119 (33.61%), Postives = 63/119 (52.94%), Query Frame = 3
Query: 1074 TCSIYEFC----NPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPI--GLYE--TFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
TC++Y F + ++I W+ + + +Y++ FA+G GP W++ SEI+P R T ++T NWF +F VT T + GL E TF + AF + +Y PE +EEI
Sbjct: 315 TCAVYFFITVNFGMTEVDIAWLSVTSVAVYIVGFALGWGPCTWLIMSEIFPVRARGTATGIATFFNWFCSFVVTKTFSALIDGLTEAGTFCFFGAFVFASVLFVYFFVPETKGKTLEEI 433 HSP 2 Score: 56.225 bits (134), Expect = 1.617e-8 Identity = 60/255 (23.53%), Postives = 114/255 (44.71%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNI-TEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAV--------NLQLVDVRYLK 946
++S P+YI+E RG + +I Q+ +T G+ ++ + ++ + + PA L++ M +PE+ RWL++K + A + + L+ P+ +I E E ++A++ + ++F L + R L+ SL Q GIN M+Y ++FQK K L+ + ++S ++ LID+ GRR L +++ G+ S AV + VD+ +L
Sbjct: 109 MASLNVPVYISETASFSNRGAMGSINQLGITAGILISYAIGYAFDWRWSA-----------VAGSFPAALLVVLMAFMPETARWLIAKKKETRARKTLLWLRG-PDYDIDKELCE--IKASI--------DTQNQRFSLKEFKNPSLLRPFLI-SMSLHFFQQFSGINAFMFYCATIFQK---AGFKDPTGVPILIGAVQFVASAISLALIDRGGRRFLLIVAGVGMSISCFTCAVYFFITVNFGMTEVDIAWLS 337
BLAST of Proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO35120 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMF8]) HSP 1 Score: 68.1662 bits (165), Expect = 3.085e-12 Identity = 56/226 (24.78%), Postives = 114/226 (50.44%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGI 886
+++ P+Y++E+ P +RG + T+ Q + GL + + L T K +L +PA+F L+ + P S R+LL + +D+ ++ V L+++ ++ + E+I E + + + + + R + + L++GC + M QL GIN ++YY+ S+F+K ++ T + + L+ + +A +L++ +GRR L LI L G+
Sbjct: 145 MNTAIAPIYLSELAPIHLRGSLGTLNQFGIVSGLLVGFIFG--LKQVLGTS---KGWQYLLGFSILPAVFQLVTLPWCPNSPRYLLIE--LDQELQAVEALRKLRATD--DVTEDINEMKIERDREATTEHVSVLQLFVR----RDLQMPLLIGCVMMMAQQLGGINAVLYYSTSIFEKVGVPESRVA---TTGIGVVALVFTAIAVRLVEVLGRRTLMLIGLGGM 354
BLAST of Proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO42861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0E6]) HSP 1 Score: 63.1586 bits (152), Expect = 1.155e-10 Identity = 31/102 (30.39%), Postives = 52/102 (50.98%), Query Frame = 3
Query: 1113 NINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVF----PIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
I+W+ + ++++ + FA+ GP+PW+V SEI+P R ++ST NW F+VT T I + T+W Y + G + PE +E+I
Sbjct: 350 KISWLAITSIVVFNLVFALAWGPVPWLVMSEIFPLQARGIASSISTLCNWSLAFAVTKTFVNIEDAITIQGTYWFYGGLSFLGFLFVLMFVPETKGKTLEQI 451 HSP 2 Score: 62.7734 bits (151), Expect = 1.211e-10 Identity = 57/249 (22.89%), Postives = 110/249 (44.18%), Query Frame = 2
Query: 215 STCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNN 961
S P+YIAEI+ +RG + ++ Q+ +T GL LA + L + + + A+ L++ M VPE+ RW LS R +A++ + + PE+++ E I EA + + + + C K L + +L Q GIN +++ + S+F + + K + ++ + + + +A ++DK GR+ L + G+ SL+ + +L Y+ Q
Sbjct: 113 SLTVPVYIAEISSPSLRGMLGSVNQLAVTMGLLLAYSMGVVLKWR-----------WLACSGAIFPALLVVLMFFVPETPRWSLSHKRRRDALDAMMWFRG-PEADVEEECYRI-EATM----------DNTQSMSCAEFCRPAIMKPLFISIALMFFQQFCGINAILFNSASIFHQAGFQDSKAV---SVIIGAVQFVGTGIACLVVDKAGRKLLLWTTALGMTVSLIALGFYFEL----YIPTTQEQ 331
BLAST of Proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO42667 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0Y9]) HSP 1 Score: 52.373 bits (124), Expect = 2.584e-7 Identity = 59/256 (23.05%), Postives = 116/256 (45.31%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRID----EAIEVVRKLKQIPESNITEF----VENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQ-------KYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFG--IIFSLVIIAVNLQL 925
+++ P+Y++EI+P +RG + T+ Q + FG+ L + S + P ++ VPA+ ++ + P S R+LL K + A++++R + E +I E +++ E +V + L R+ K R L++G +QM QL GIN ++YY+ ++ +Y T + I +P + L++ +GRR L L L G I++ ++ + +L++
Sbjct: 125 LNTAVVPIYLSEISPIQLRGSLGTLNQFGICFGILLGYIFGLKEVLGSGSK-----WPWLIGFSIVPAIIQMMTLPFCPRSPRYLLLKRNKEADAVHALQILRGTNDVSE-DIAEMRIEQEQSLREPHVSVTS------------LFRL---KHLRMPLLIGVVMQMSQQLSGINSVIYYSTTILDEAHIPGSRYATLGVGI---ISP--------DKDRSGGLVEVLGRRTLMLWGLGGMCIMYGVITLGFSLKV 348
BLAST of Proton myo-inositol cotransporter vs. Ensembl Medaka
Match: slc2a13b (proton myo-inositol cotransporter [Source:NCBI gene;Acc:101158939]) HSP 1 Score: 135.191 bits (339), Expect = 9.177e-34 Identity = 87/283 (30.74%), Postives = 148/283 (52.30%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV-----DVRYLKRNQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RG+++T+ + +T G F+AS+V+ +Y S +L +PA+ +G + +PES RWLL K + EA++V+R ++ + N+ E ++I +AN+ E+ +++ +L R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + K +W + N + + V L++++GRRKL L SL G SL ++AV L V + NN CE C +D + G+
Sbjct: 141 IASMTVPVYIAEVSPPHLRGQLVTVNALFITGGQFIASMVDGAFSYLSE-----DGWRYMLGLSVLPAVLQFLGFIFLPESPRWLLQKGQNQEALQVLRWIRG--DQNVEEEYDSI-KANI---EEEEKEVGAGGVVLLRMLSHGPTRRALIVGCGLQMFQQLSGINTVMYYSATILQMAGVRDDKEAIWLAAATSATNFVFTLVGVWLVERVGRRKLTLGSLLGTGLSLALLAVGFLLSAQSSPPVTLHPVDPNNSTYRLYGS-------CEPCMLDPDCGF 405 HSP 2 Score: 77.7962 bits (190), Expect = 7.864e-15 Identity = 41/86 (47.67%), Postives = 52/86 (60.47%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFWIYSAFTL 1343
Y +C S +WI+L+G+ LY+ FA GMGP+PW V SEIYP W RST A S NW FN V++T + Y T+ Y AF L
Sbjct: 449 YNYCPTS---YSWIVLMGLFLYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWIFNVLVSLTFLHVAEYLTY--YGAFFL 529
BLAST of Proton myo-inositol cotransporter vs. Ensembl Medaka
Match: slc2a13b (proton myo-inositol cotransporter [Source:NCBI gene;Acc:101158939]) HSP 1 Score: 135.191 bits (339), Expect = 1.018e-33 Identity = 87/283 (30.74%), Postives = 148/283 (52.30%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV-----DVRYLKRNQNNICDNFLACDDWVSYHCEYCQIDENSGY 1042
I+S P+YIAE++P +RG+++T+ + +T G F+AS+V+ +Y S +L +PA+ +G + +PES RWLL K + EA++V+R ++ + N+ E ++I +AN+ E+ +++ +L R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + K +W + N + + V L++++GRRKL L SL G SL ++AV L V + NN CE C +D + G+
Sbjct: 141 IASMTVPVYIAEVSPPHLRGQLVTVNALFITGGQFIASMVDGAFSYLSEDGWR-----YMLGLSVLPAVLQFLGFIFLPESPRWLLQKGQNQEALQVLRWIRG--DQNVEEEYDSI-KANI---EEEEKEVGAGGVVLLRMLSHGPTRRALIVGCGLQMFQQLSGINTVMYYSATILQMAGVRDDKEAIWLAAATSATNFVFTLVGVWLVERVGRRKLTLGSLLGTGLSLALLAVGFLLSAQSSPPVTLHPVDPNNSTYRLYG-------SCEPCMLDPDCGF 405 HSP 2 Score: 77.7962 bits (190), Expect = 9.007e-15 Identity = 41/86 (47.67%), Postives = 52/86 (60.47%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFWIYSAFTL 1343
Y +C S +WI+L+G+ LY+ FA GMGP+PW V SEIYP W RST A S NW FN V++T + Y T+ Y AF L
Sbjct: 449 YNYCPTS---YSWIVLMGLFLYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWIFNVLVSLTFLHVAEYLTY--YGAFFL 529
BLAST of Proton myo-inositol cotransporter vs. Ensembl Medaka
Match: SLC2A13 (solute carrier family 2 member 13 [Source:NCBI gene;Acc:101157657]) HSP 1 Score: 110.153 bits (274), Expect = 1.054e-25 Identity = 78/273 (28.57%), Postives = 139/273 (50.92%), Query Frame = 2
Query: 227 PLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSYH-CEYCQIDENSGY 1042
P+YIAE +P +RG+++T+ + +T G F AS+++ +Y +L +PA+ +G L +PES RWL+ + +A V+ +++ NI E ++I + E+ ++ ++ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W L T N + + + L++K+GRRKL L S+ G SL ++AV L+ ++ D +A Y CE C +D + G+
Sbjct: 4 PVYIAEASPPHLRGQLVTVNTLFITGGQFTASLIDGAFSYLQH-----DGWRYMLGLSVIPAVLQFLGFLFLPESPRWLIQRGLTQKARRVLSQIRG--NQNIDEEYDSIKNS----IEEEEKDSGGDGPVVWRMLTYPPTRRALLVGCGLQMFQQLSGINTVMYYSATILQMSGVRDDRLAIWLAGLATLTNFLFTLLGVWLVEKVGRRKLTLGSILGTTLSLSLLAVGF-LMSAQHSPPVTFRPLDPAMANSTCSKYRLCEPCMLDPSCGF 264 HSP 2 Score: 89.7373 bits (221), Expect = 7.592e-19 Identity = 45/111 (40.54%), Postives = 63/111 (56.76%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYET----FWIYSAFTLCGIALIYRNFPEMNQANMEEI 1406
Y +C S W++LLG+++Y +FA GMGP+PW + SEIYP W RST A + NW FN V++T + Y T F++YS+ L G +Y PE +EEI
Sbjct: 308 YNYCPTSYF---WLVLLGLVMYFAAFAPGMGPMPWTINSEIYPLWARSTGNACAAGVNWTFNILVSVTFLHLAQYLTYYGVFFLYSSLALLGFVFVYGCLPETKARRLEEI 415
BLAST of Proton myo-inositol cotransporter vs. Ensembl Medaka
Match: SLC2A13 (solute carrier family 2 member 13 [Source:NCBI gene;Acc:101157657]) HSP 1 Score: 110.923 bits (276), Expect = 1.816e-25 Identity = 78/273 (28.57%), Postives = 139/273 (50.92%), Query Frame = 2
Query: 227 PLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSYH-CEYCQIDENSGY 1042
P+YIAE +P +RG+++T+ + +T G F AS+++ +Y +L +PA+ +G L +PES RWL+ + +A V+ +++ NI E ++I + E+ ++ ++ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W L T N + + + L++K+GRRKL L S+ G SL ++AV L+ ++ D +A Y CE C +D + G+
Sbjct: 196 PVYIAEASPPHLRGQLVTVNTLFITGGQFTASLIDGAFSYLQHDG-----WRYMLGLSVIPAVLQFLGFLFLPESPRWLIQRGLTQKARRVLSQIRG--NQNIDEEYDSIKNS----IEEEEKDSGGDGPVVWRMLTYPPTRRALLVGCGLQMFQQLSGINTVMYYSATILQMSGVRDDRLAIWLAGLATLTNFLFTLLGVWLVEKVGRRKLTLGSILGTTLSLSLLAVGF-LMSAQHSPPVTFRPLDPAMANSTCSKYRLCEPCMLDPSCGF 456 HSP 2 Score: 73.9442 bits (180), Expect = 1.534e-13 Identity = 34/79 (43.04%), Postives = 49/79 (62.03%), Query Frame = 3
Query: 1086 YEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFW 1322
Y +C S W++LLG+++Y +FA GMGP+PW + SEIYP W RST A + NW FN V++T + Y T++
Sbjct: 500 YNYCPTSYF---WLVLLGLVMYFAAFAPGMGPMPWTINSEIYPLWARSTGNACAAGVNWTFNILVSVTFLHLAQYLTYY 575
BLAST of Proton myo-inositol cotransporter vs. Ensembl Medaka
Match: slc2a1a (solute carrier family 2, facilitated glucose transporter member 1-like [Source:NCBI gene;Acc:101161039]) HSP 1 Score: 79.337 bits (194), Expect = 1.881e-15 Identity = 61/247 (24.70%), Postives = 124/247 (50.20%), Query Frame = 2
Query: 200 HFRISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASV--VNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVD 931
H +S+ P+Y+ EI+P +RG + T++Q+ + G+ +A + + + + AS P++L VPA+ + + PES R+LL ++N +A V+ KL+ E ++E ++ + E + + + + + + + R+ +++ LQ+ QL GIN + YY+ +F++ + ++ T +N + V+ ++++ GRR L LI L G+ S V + V + L D
Sbjct: 120 HSGLSTGFVPMYVEEISPTSLRGAMGTLHQLGVVIGILVAQIFGLESIMGNAS-------LWPLLLGFTLVPAILQCVLLPFCPESPRYLLINRNEESKACSVLMKLRGTDE--VSEDIQEMREESQKMMREKKVT-------IAELFRSPVYRQPMIVAIMLQLSQQLSGINAVFYYSTGIFER---AGVAQPVYATIGAGVVNTAFTVVSLFVVERTGRRPLHLIGLMGMAVSAVFLTVAMALQD 347
BLAST of Proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056331.1 (SMESG000056331.1) HSP 1 Score: 314.694 bits (805), Expect = 2.103e-127 Identity = 175/283 (61.84%), Postives = 222/283 (78.45%), Query Frame = 2
Query: 218 TCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSYHCEYCQIDENSGYTCVNYGAN 1066
TCCPLYIAE+TPK+IRGR+IT+YQ+ +TFG+ LAS+V A++ R ++ I+L TP +PA+ +LIGMLTV ESYRWLL+KNR DEA EV+RKLKQ+ ES+I EFV+ ILEAN++IEE+ +++ F+L RIL +KIARK+L+ GC +Q++ Q+ GIN ++Y + LFQ + + + LWF L+ F N I SFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV VR L NQNN C NFL+CDD ++ +CEYCQIDE+SGYTCVN GAN
Sbjct: 124 TCCPLYIAEMTPKLIRGRVITLYQVSITFGILLASIVKASIC------RKDESYIIVLTTPLIPAIIVLIGMLTVSESYRWLLTKNRKDEAKEVIRKLKQLQESSIEEFVKIILEANIVIEEENSQKR----FMLFRILRNKIARKSLLFGCYIQIIGQIAGINAILYNSPLLFQYFNNMSYERALWFGSLIYFFNFIPSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVYVRRL--NQNNNCSNFLSCDDCINNYCEYCQIDESSGYTCVNSGAN 394 HSP 2 Score: 161.77 bits (408), Expect = 2.103e-127 Identity = 81/117 (69.23%), Postives = 89/117 (76.07%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 1418
G SIY F NP T INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALST A W N T+ F Y FWIY AFT+CGIALIY+ FPE NQ ++E++ +VL
Sbjct: 398 KGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSRIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 514 HSP 3 Score: 65.855 bits (159), Expect = 3.000e-11 Identity = 28/45 (62.22%), Postives = 37/45 (82.22%), Query Frame = 3
Query: 51 MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTETV 185
MNF+ S+DSL+D IEV +T Q+IH+I FP+IGGFMFG+VT +V
Sbjct: 1 MNFDISLDSLYDINKIEVYFTRQYIHHIIFPMIGGFMFGHVTGSV 45
BLAST of Proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056331.1 (SMESG000056331.1) HSP 1 Score: 314.309 bits (804), Expect = 2.403e-127 Identity = 175/283 (61.84%), Postives = 222/283 (78.45%), Query Frame = 2
Query: 218 TCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPKTMPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVDVRYLKRNQNNICDNFLACDDWVSYHCEYCQIDENSGYTCVNYGAN 1066
TCCPLYIAE+TPK+IRGR+IT+YQ+ +TFG+ LAS+V A++ R ++ I+L TP +PA+ +LIGMLTV ESYRWLL+KNR DEA EV+RKLKQ+ ES+I EFV+ ILEAN++IEE+ +++ F+L RIL +KIARK+L+ GC +Q++ Q+ GIN ++Y + LFQ + + + LWF L+ F N I SFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLV VR L NQNN C NFL+CDD ++ +CEYCQIDE+SGYTCVN GAN
Sbjct: 93 TCCPLYIAEMTPKLIRGRVITLYQVSITFGILLASIVKASI------CRKDESYIIVLTTPLIPAIIVLIGMLTVSESYRWLLTKNRKDEAKEVIRKLKQLQESSIEEFVKIILEANIVIEEENSQKR----FMLFRILRNKIARKSLLFGCYIQIIGQIAGINAILYNSPLLFQYFNNMSYERALWFGSLIYFFNFIPSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVYVRRL--NQNNNCSNFLSCDDCINNYCEYCQIDESSGYTCVNSGAN 363 HSP 2 Score: 161.384 bits (407), Expect = 2.403e-127 Identity = 81/117 (69.23%), Postives = 89/117 (76.07%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 1418
G SIY F NP T INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALST A W N T+ F Y FWIY AFT+CGIALIY+ FPE NQ ++E++ +VL
Sbjct: 367 KGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSRIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 483
BLAST of Proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056325.1 (SMESG000056325.1) HSP 1 Score: 221.476 bits (563), Expect = 6.070e-69 Identity = 108/117 (92.31%), Postives = 108/117 (92.31%), Query Frame = 3
Query: 1068 NGTCSIYEFCNPSTININWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFPIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 1418
G SIY F NP T INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVF IGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL
Sbjct: 139 KGNYSIYNFHNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFAIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 255 HSP 2 Score: 99.7525 bits (247), Expect = 1.599e-23 Identity = 49/49 (100.00%), Postives = 49/49 (100.00%), Query Frame = 2
Query: 431 MLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI 577
MLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI
Sbjct: 1 MLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI 49
BLAST of Proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056326.1 (SMESG000056326.1) HSP 1 Score: 116.701 bits (291), Expect = 1.853e-30 Identity = 55/55 (100.00%), Postives = 55/55 (100.00%), Query Frame = 2
Query: 209 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPK 373
ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPK
Sbjct: 118 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTDRSPK 172 HSP 2 Score: 99.3673 bits (246), Expect = 3.660e-24 Identity = 48/58 (82.76%), Postives = 52/58 (89.66%), Query Frame = 3
Query: 51 MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTETVPNVYGIFVFLLLA 224
MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVT T+P+V G L++A
Sbjct: 1 MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTIPDVNGTSHMLIVA 58
BLAST of Proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056221.1 (SMESG000056221.1) HSP 1 Score: 74.7146 bits (182), Expect = 3.442e-14 Identity = 33/64 (51.56%), Postives = 45/64 (70.31%), Query Frame = 2
Query: 386 ILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI 577
+L A+P+ IGMLTVPESYRWLLSKN++DEA ++ Q+PE ITE+++ I+ AN I
Sbjct: 146 MLGGAAIPSFIEFIGMLTVPESYRWLLSKNKVDEARTIIVNQGQVPEERITEYIDEIVRANQQI 209 The following BLAST results are available for this feature:
BLAST of Proton myo-inositol cotransporter vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Proton myo-inositol cotransporter vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Proton myo-inositol cotransporter vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30017038 ID=SMED30017038|Name=Proton myo-inositol cotransporter|organism=Schmidtea mediterranea sexual|type=transcript|length=1477bpback to top protein sequence of SMED30017038-orf-1 >SMED30017038-orf-1 ID=SMED30017038-orf-1|Name=SMED30017038-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=231bp MPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPEback to top protein sequence of SMED30017038-orf-2 >SMED30017038-orf-2 ID=SMED30017038-orf-2|Name=SMED30017038-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=145bp MTGLVITVNIVKLTKIPDILVLIMGQTNGTCSIYEFCNPSTININWILLLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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