AP-2 complex subunit alpha

Overview


Name	AP-2 complex subunit alpha
Smed ID	SMED30017036
Length (bp)	2958

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of AP-2 complex subunit alpha (SMED30017036) t-SNE clustered cells

Violin plots show distribution of expression levels for AP-2 complex subunit alpha (SMED30017036) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of AP-2 complex subunit alpha (SMED30017036) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for AP-2 complex subunit alpha (SMED30017036) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017036

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30017036	h1SMcG0008013	Contig45205	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30017036	h1SMcG0008013	Contig45205	newmark_ests	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30017036	h1SMcG0008013	dd_Smed_v4_1423_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30017036	h1SMcG0008013	dd_Smed_v4_1423_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30017036	h1SMcG0008013	dd_Smed_v4_1423_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30017036	h1SMcG0008013	dd_Smed_v4_1423_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30017036	h1SMcG0008013	dd_Smed_v4_1423_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

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Homology

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Human
Match: AP2A2 (adaptor related protein complex 2 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:562])

HSP 1 Score: 1212.21 bits (3135), Expect = 0.000e+0
Identity = 605/971 (62.31%), Postives = 735/971 (75.70%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSD--------------INENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIES 2890
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIA++G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L R +PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA +IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS LRNADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+  K    T  D   TK +   + VD+ GG      P  T++ ST  P++DLL         +                +++ S   P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C+      L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE Q++ K+ K PM+  V + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++K+ VS+++  ++ +
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEDTKRD---RSVDVNGG--PEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEGGAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKA-KHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSA 938

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Human
Match: AP2A2 (adaptor related protein complex 2 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:562])

HSP 1 Score: 1208.74 bits (3126), Expect = 0.000e+0
Identity = 606/971 (62.41%), Postives = 735/971 (75.70%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSD--------------INENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIES 2890
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIA++G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L R +PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPPD A VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA +IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS LRNADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+  K    T  D   TK +   + VD+ GG      P  T++ ST  P++DLL         +                +++ S   P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C+      L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE Q++ K+ K PM+  V + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++K+ VS+++  ++ +
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPA-VRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEDTKRD---RSVDVNGG--PEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEGGAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKA-KHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSA 937

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Human
Match: AP2A1 (adaptor related protein complex 2 subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:561])

HSP 1 Score: 1194.49 bits (3089), Expect = 0.000e+0
Identity = 605/965 (62.69%), Postives = 728/965 (75.44%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNP-----------ITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPP-TTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA +IPR+LV+GD++DSVKQSAALCLL+L +A+PDLV   +WT+RV+HLLNDQHMGVVTAAVSLI  L K++P+++K CVSLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+DA V+ RL ECLE++L+KAQEPPKSKKVQHSNAKNA+LFE I+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H +TVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EML YLE+ADY+IREE+VLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RV+QIV NR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLSTY+KFINLFPE K  IQ +L+  S LRNADVE+QQR +EYLTLS +A+ DV+ATVLEEMP F ERESSILAKLK+KK     G  L   R+ P++      ++    +P+T   P+    DLLG            +   S    +LL+D+    FD    +      P           I     E+DE   K + K++G+LFEN  +QIG+KSEFR N+GR+ +FYGNK+  Q  +F   + +     T L +    + + +  G Q QQ LNIEC + F     L V F        + L LP+TINKF +   M    FFQRWK L  P QE Q + K+   PM+  V + +L G   ++L N+DP   NFV +GI+   + +VG LLRLEPN   ++YRLT+R++K+ VSR +  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGA-GSALDDGRRDPSSNDINGGMEP---TPSTVSTPS-PSADLLG----LRAAPPPAAPPASAGAGNLLVDV----FDGPAAQPSLGPTPEEAFLSPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKA-NHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELL 951

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Human
Match: AP2A1 (adaptor related protein complex 2 subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:561])

HSP 1 Score: 1188.33 bits (3073), Expect = 0.000e+0
Identity = 606/984 (61.59%), Postives = 733/984 (74.49%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGN-------------GFDSDINENKSSTNPITLEQ-----------------SESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPP-TTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA +IPR+LV+GD++DSVKQSAALCLL+L +A+PDLV   +WT+RV+HLLNDQHMGVVTAAVSLI  L K++P+++K CVSLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+DA V+ RL ECLE++L+KAQEPPKSKKVQHSNAKNA+LFE I+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H +TVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EML YLE+ADY+IREE+VLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RV+QIV NR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLSTY+KFINLFPE K  IQ +L+  S LRNADVE+QQR +EYLTLS +A+ DV+ATVLEEMP F ERESSILAKLK+KK     G  L   R+ P++      ++    +P+T   P+    DLLG            +   S    +LL+D+                 F S++ E  +  +P+ L                    E+DE   K + K++G+LFEN  +QIG+KSEFR N+GR+ +FYGNK+  Q  +F   + +     T L +    + + +  G Q QQ LNIEC + F     L V F        + L LP+TINKF +   M    FFQRWK L  P QE Q + K+   PM+  V + +L G   ++L N+DP   NFV +GI+   + +VG LLRLEPN   ++YRLT+R++K+ VSR +  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGA-GSALDDGRRDPSSNDINGGMEP---TPSTVSTPS-PSADLLG----LRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSEL-EPPAPESPMALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKA-NHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELL 973

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BLAST of AP-2 complex subunit alpha vs. Ensembl Human
Match: AP2A2 (adaptor related protein complex 2 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:562])

HSP 1 Score: 1170.61 bits (3027), Expect = 0.000e+0
Identity = 586/948 (61.81%), Postives = 715/948 (75.42%), Query Frame = 2

Query:   95 KSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSD--------------INENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIES 2890
            KSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIA++G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L R +PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPPD A VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA +IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS LRNADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+  K    T  D   TK +   + VD+ GG      P  T++ ST  P++DLL         +                +++ S   P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C+      L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE Q++ K+ K PM+  V + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++K+ VS+++  ++ +
Sbjct:    2 KSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPA-VRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEDTKRD---RSVDVNGG--PEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEGGAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKA-KHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSA 915

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BLAST of AP-2 complex subunit alpha vs. Ensembl Celegans
Match: apa-2 (AP-2 complex subunit alpha [Source:UniProtKB/TrEMBL;Acc:Q22601])

HSP 1 Score: 1164.06 bits (3010), Expect = 0.000e+0
Identity = 584/965 (60.52%), Postives = 725/965 (75.13%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXX-XXXXEGQELIAPRQHPTAKISKNS-----LDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLN--PIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEK-----QSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP VKGD MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLG+DIDFGH EAVNLL SNKYTEKQIGYLFISVLI +  +LM L+VQ +++DL+SRNPV V LALQCI+N+G+REM E F  ++P+LLVSG+TID VKQSAALC+LKL R +PD     D+ SR++HLLND HMGVVT+A SLIE+L K+ PEEYK  V LA+SRLSRIVT++YTDLQDYTYYFVPAPWL VKLLRLLQNYPPPDD   ++RL ECLE IL+KAQ+ PKSKKVQHSNAKNAVLFEAI LIIHMD +P LL+RACNQLG FLSHRETNLRYLALESMCLLATSEFSH+AVKKHQ+T+I++LK+ERDVSVRQRAVDLLYAMCDR+NA +IV EML+YLE+ADYSIREEMVLKVAIL+EKYATDY+WYVD IL LIR+AGDYVSEEVW+RVIQIV+NR DVQGY+AKTVFEALQ PACHENMVKVGGYILGEFGN IAGD RS+ +IQF++LH+K+HLC+ TTR LLL+TY+KF NLFPEIK  +Q + + D NLRN D E+QQR+IEYL ++K+A++DV+AT+LE MP+F E+ESS+LAKLK+ K       +E    R  PTA +S+ S      D+ ND+ A+                                 +D+  +  G G  +  +E         +E +  D+ YLK + KS+ IL+E+D IQIG K E R N+GRLG+FYGNK+ +    F T +   P    ++L     P++  +A+G Q QQ +N  C Q F +   + + F         Q++     LP+ I+KF E   M    FF RWK L    QE Q +  +L  P+E + +++RL+G   ++L+++DP   N+V +GI++  +Q++G L+RLEPN   K+YRLT+RS+KD V + + +++
Sbjct:    1 MPAVKGDGMRGLAVFISDIRNCKSKEAELKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGNDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQGIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTDLPKLLVSGETIDFVKQSAALCILKLFRNSPDSFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATYTDLQDYTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQLGTFLSHRETNLRYLALESMCLLATSEFSHDAVKKHQDTIINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAEMLAYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILKLIRIAGDYVSEEVWYRVIQIVVNREDVQGYAAKTVFEALQRPACHENMVKVGGYILGEFGNFIAGDERSTAKIQFELLHSKFHLCSITTRCLLLTTYIKFCNLFPEIKPLVQQVFQTDHNLRNPDAELQQRSIEYLQMTKLASNDVLATILEVMPAFAEKESSLLAKLKKSKPQLEEIEREEKEKRSKPTAVMSEGSTSLVDFDSTNDTTAS--------------------------------LADVFANNSGTGLGAQGDE---------VEIANKDD-YLKFVTKSNAILWEDDYIQIGCKLETRNNLGRLGMFYGNKTSQPFNKF-TPIITCPGALAVQLQAQAKPVEPVVAAGTQVQQLINFVCVQEFQKMPIMNIKFTFTDRAGAVQNFDKNFYLPLFISKFFEPTNMTSEQFFTRWKSLGAASQEAQKIFNALS-PIEHATIESRLKGFGANLLTDVDPNPDNYVCAGIIHTQTQQIGTLIRLEPNKQAKMYRLTIRSSKDTVVQTLVDLL 921

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Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXX-XXXXEGQELIAPRQHPTAKISKNS-----LDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLN--PIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEK-----QSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP VKGD MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLG+DIDFGH EAVNLL SNKYTEKQIGYLFISVLI +  +LM L+VQ +++DL+SRNPV V LALQCI+N+G+REM E F  ++P+LLVSG+TID VKQSAALC+LKL R +PD     D+ SR++HLLND HMGVVT+A SLIE+L K+ PEEYK  V LA+SRLSRIVT++YTDLQDYTYYFVPAPWL VKLLRLLQNYPPPDD   ++RL ECLE IL+KAQ+ PKSKKVQHSNAKNAVLFEAI LIIHMD +P LL+RACNQLG FLSHRETNLRYLALESMCLLATSEFSH+AVKKHQ+T+I++LK+ERDVSVRQRAVDLLYAMCDR+NA +IV EML+YLE+ADYSIREEMVLKVAIL+EKYATDY+WYVD IL LIR+AGDYVSEEVW+RVIQIV+NR DVQGY+AKTVFEALQ PACHENMVKVGGYILGEFGN IAGD RS+ +IQF++LH+K+HLC+ TTR LLL+TY+KF NLFPEIK  +Q + + D NLRN D E+QQR+IEYL ++K+A++DV+AT+LE MP+F E+ESS+LAKLK+ K       +E    R  PTA +S+ S      D+ ND+ A+                                 +D+  +  G G  +  +E         +E +  D+ YLK + KS+ IL+E+D IQIG K E R N+GRLG+FYGNK+ +    F T +   P    ++L     P++  +A+G Q QQ +N  C Q F +   + + F         Q++     LP+ I+KF E   M    FF RWK L    QE Q +  +L  P+E + +++RL+G   ++L+++DP   N+V +GI++  +Q++G L+RLEPN   K+YRLT+RS+KD V + + +++
Sbjct:    1 MPAVKGDGMRGLAVFISDIRNCKSKEAELKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGNDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQGIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTDLPKLLVSGETIDFVKQSAALCILKLFRNSPDSFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATYTDLQDYTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQLGTFLSHRETNLRYLALESMCLLATSEFSHDAVKKHQDTIINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAEMLAYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILKLIRIAGDYVSEEVWYRVIQIVVNREDVQGYAAKTVFEALQRPACHENMVKVGGYILGEFGNFIAGDERSTAKIQFELLHSKFHLCSITTRCLLLTTYIKFCNLFPEIKPLVQQVFQTDHNLRNPDAELQQRSIEYLQMTKLASNDVLATILEVMPAFAEKESSLLAKLKKSKPQLEEIEREEKEKRSKPTAVMSEGSTSLVDFDSTNDTTAS--------------------------------LADVFANNSGTGLGAQGDE---------VEIANKDD-YLKFVTKSNAILWEDDYIQIGCKLETRNNLGRLGMFYGNKTSQPFNKF-TPIITCPGALAVQLQAQAKPVEPVVAAGTQVQQLINFVCVQEFQKMPIMNIKFTFTDRAGAVQNFDKNFYLPLFISKFFEPTNMTSEQFFTRWKSLGAASQEAQKIFNALS-PIEHATIESRLKGFGANLLTDVDPNPDNYVCAGIIHTQTQQIGTLIRLEPNKQAKMYRLTIRSSKDTVVQTLVDLL 921

[Close]

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXX-XXXXEGQELIAPRQHPTAKISKNS-----LDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLN--PIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEK-----QSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP VKGD MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLG+DIDFGH EAVNLL SNKYTEKQIGYLFISVLI +  +LM L+VQ +++DL+SRNPV V LALQCI+N+G+REM E F  ++P+LLVSG+TID VKQSAALC+LKL R +PD     D+ SR++HLLND HMGVVT+A SLIE+L K+ PEEYK  V LA+SRLSRIVT++YTDLQDYTYYFVPAPWL VKLLRLLQNYPPPDD   ++RL ECLE IL+KAQ+ PKSKKVQHSNAKNAVLFEAI LIIHMD +P LL+RACNQLG FLSHRETNLRYLALESMCLLATSEFSH+AVKKHQ+T+I++LK+ERDVSVRQRAVDLLYAMCDR+NA +IV EML+YLE+ADYSIREEMVLKVAIL+EKYATDY+WYVD IL LIR+AGDYVSEEVW+RVIQIV+NR DVQGY+AKTVFEALQ PACHENMVKVGGYILGEFGN IAGD RS+ +IQF++LH+K+HLC+ TTR LLL+TY+KF NLFPEIK  +Q + + D NLRN D E+QQR+IEYL ++K+A++DV+AT+LE MP+F E+ESS+LAKLK+ K       +E    R  PTA +S+ S      D+ ND+ A+                                 +D+  +  G G  +  +E         +E +  D+ YLK + KS+ IL+E+D IQIG K E R N+GRLG+FYGNK+ +    F T +   P    ++L     P++  +A+G Q QQ +N  C Q F +   + + F         Q++     LP+ I+KF E   M    FF RWK L    QE Q +  +L  P+E + +++RL+G   ++L+++DP   N+V +GI++  +Q++G L+RLEPN   K+YRLT+RS+KD V + + +++
Sbjct:    1 MPAVKGDGMRGLAVFISDIRNCKSKEAELKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGNDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQGIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTDLPKLLVSGETIDFVKQSAALCILKLFRNSPDSFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATYTDLQDYTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQLGTFLSHRETNLRYLALESMCLLATSEFSHDAVKKHQDTIINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAEMLAYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILKLIRIAGDYVSEEVWYRVIQIVVNREDVQGYAAKTVFEALQRPACHENMVKVGGYILGEFGNFIAGDERSTAKIQFELLHSKFHLCSITTRCLLLTTYIKFCNLFPEIKPLVQQVFQTDHNLRNPDAELQQRSIEYLQMTKLASNDVLATILEVMPAFAEKESSLLAKLKKSKPQLEEIEREEKEKRSKPTAVMSEGSTSLVDFDSTNDTTAS--------------------------------LADVFANNSGTGLGAQGDE---------VEIANKDD-YLKFVTKSNAILWEDDYIQIGCKLETRNNLGRLGMFYGNKTSQPFNKF-TPIITCPGALAVQLQAQAKPVEPVVAAGTQVQQLINFVCVQEFQKMPIMNIKFTFTDRAGAVQNFDKNFYLPLFISKFFEPTNMTSEQFFTRWKSLGAASQEAQKIFNALS-PIEHATIESRLKGFGANLLTDVDPNPDNYVCAGIIHTQTQQIGTLIRLEPNKQAKMYRLTIRSSKDTVVQTLVDLL 921

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BLAST of AP-2 complex subunit alpha vs. Ensembl Celegans
Match: apg-1 (AP-1 complex subunit gamma [Source:UniProtKB/TrEMBL;Acc:Q8WQB3])

HSP 1 Score: 259.996 bits (663), Expect = 1.736e-73
Identity = 179/611 (29.30%), Postives = 328/611 (53.68%), Query Frame = 2

Query:   44 GDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACH-ENMVKVGGYILGEFGNLI--AGDPRSSPQIQFQILHA-----KYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFT 1843
            G  MR L   I  +R  ++   E   ++RE ANIR  F+ D   D   K + + KLL+I +LG+   FG  E + L+   ++T+K+IGYL   +L++E   +  LV   LK+DL+        LAL  + +I + EM  + A E+ +++   +    +K+ AALC  +++R  P+L+      +R   LL +++ GV+  A +L+  + ++SP+    +K  V   V  L  ++ S Y+   D T   +  P+L VK+LRLL+     D      R+TE +  IL++     ++ K    N  NA+L+E +  I+ +  +  L I A N LG+FL + + N+RY+AL +  LL T    ++AV++H+  V+  LK + D+S+R+RA++L +A+ +R N   +  E+L +LE+AD   + E   ++ I +E+Y+ ++ W++DT++ ++R+AG YV +EV   +IQ++     +Q Y+   ++ A Q  A + + +++V  + +GEFG+L+    D  S+P  +  ++          L +  T+   ++   K    F    + I  +++   N  +  +E+QQR++E+  +  +   D+   +LE MP  T
Sbjct:   24 GTPMR-LRDLIRQVRAARTMAEERAVVDRESANIRESFRDD---DSPWKCRNIAKLLYIHMLGYPAHFGQMECMKLVAHPRFTDKRIGYLGAMLLLDERSEVHMLVTNSLKNDLTCSTQFVSGLALCTLGSICSAEMCRDLANEVEKIIKQNNAY--LKKKAALCAFRIVRKVPELMEVFIPCTR--SLLGEKNHGVLMGATTLVTEMCEKSPDVLNHFKKLVPNLVRILKNLLMSGYSPEHDVTG--ISDPFLQVKILRLLRVLGKDD-----VRVTEEMNDILAQVATNTETAK----NVGNAILYETVLTIMEIKSESGLRILAVNILGRFLLNTDKNIRYVALNT--LLKTVHVDYQAVQRHRNVVVECLK-DPDISIRKRAMELCFALMNRTNIAIMTKEVLIFLETADAEFKSECASRMYIATERYSPNHEWHLDTMITVLRLAGKYVPDEVVSCMIQMISANEQLQSYAVSQLYHAAQKDAINAQPLLQVAFWTIGEFGDLLLQPTDVDSTPISENDVVGVFESVLPSALTSLWTKCYGVTALAKLGTRFQSTGDRIGALVR--MNQAHIQLELQQRSVEFNVILNLG--DLRDGLLERMPVIT 608

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BLAST of AP-2 complex subunit alpha vs. Ensembl Celegans
Match: apd-3 (AP-3 complex subunit delta [Source:UniProtKB/TrEMBL;Acc:Q95X88])

HSP 1 Score: 134.035 bits (336), Expect = 1.441e-31
Identity = 127/522 (24.33%), Postives = 246/522 (47.13%), Query Frame = 2

Query:   56 RGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHM------DCDPNLLIRACNQ-LGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYS-IREEMVLKVAILSE----KYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACH----------ENMVKV---GGYILGEF 1546
            + L   I  IRN K  E+  + I + +  I+ + + D     Y K   + KL ++ +LG+DI +     + ++ S KYTEK+IGYL  +   ++  +++ L    ++ D++S N     +AL  ++   T ++  + A ++  LL    + +  ++ A L L K+    PD +       R+   L D   GV ++AV++I  L +++P+ Y   ++LA      + TSS               W+ +K+++L     P             LE  L K    P +  +  ++A  ++L+E IN +I +        D    I+ C Q LG  +   + NL+YL L +M  +  +    +AV+ H++ V+  L  ++D S+R R++DLLY M  + N  EIV +++ ++E+A+ S  R+E++ ++  +      +Y T++ WY+  ++ L +V G     ++  ++  + +    ++ +S   +  AL     H           NM +V     +I GE+
Sbjct:   16 KSLTDLIRGIRNNKDNES--RYITQCMEEIKQELRQDSI---YVKANAIEKLAYLQMLGYDISWASFNVIEVMASTKYTEKRIGYLAAAQSFHDETDVLMLTTNLIRKDVNSSNMYESGIALGGLSCFVTPDLARDLAADVVNLLSC--SRNYTRKRAVLLLYKIFLKYPDALR--PTFPRLKEKLEDPDPGVQSSAVNVICELARKNPKNY---LTLAPVFFKLMTTSSNN-------------WMLIKIIKLFGALVP-------------LEPRLGKKLLEPLTNLINSTSAM-SLLYECINTVIAVLISISAGGDHTASIQLCVQKLGVLIEDSDQNLKYLGLLAMGKILKTH--PKAVQAHKDIVLRCL-DDKDESIRIRSLDLLYGMVSKKNIVEIVKKLMEHVEAAEGSHYRDELLSRIIGICSWSNYQYITNFEWYISVLVELTKVEGTEHGAKIAEQIQDVTVRVESIRHFSVSQM--ALLVENAHVLLAGSAQQRSNMCEVLLAAAWICGEY 493

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BLAST of AP-2 complex subunit alpha vs. Ensembl Fly
Match: AP-2alpha (gene:FBgn0264855 transcript:FBtr0089488)

HSP 1 Score: 1206.05 bits (3119), Expect = 0.000e+0
Identity = 609/955 (63.77%), Postives = 744/955 (77.91%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPP-PDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQ-HPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI-LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            M  V+GD MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKY+EKQIGYLFISVL+N + +L+ L++Q +K+DL SRNPV V LALQCIANIG+R+M E+F+ EIP+LLVSGDT+D VKQSAALCLL+L R++PD++   +WTSR+IHLLNDQHMGVVTAA SLI++LVKR+P+EYK CV+LAVSRLSRIVT+SYTDLQDYTYYFVPAPWLSVKLLRLLQNY P  ++A VR+RL E LE+IL+KAQEPPKSKKVQHSNAKNAVLFEAINLIIH D +PNLL+RACNQLGQFLS+RETNLRYLALESMC LATSEFSHE VKKHQE VI ++K E+DVSVRQ AVDLLYAMCDR NAEEIV EML+YLE+ADYSIREEMVLKVAIL+EKYATDY+WYVD ILNLIR+AGDYVSEEVW+RVIQIVINR +VQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGD RS+P +QF++LH+KYHLC+P TR LLLSTY+KFINLFPEI+  IQD+ +  SNLR+AD E+QQR  EYL LS +A+ DV+ATVLEEMPSF ERESSILA LK+KKP  +   E+   +   P    ++N+    N         A    DLLG   S    N   S S S  T   L+D+LG+ + S+ N N S+             N  K L+K++G+LFEN+ +QIG+KSEFR N+GRLG+FYGNK+   +T+F   L  S    + L + +  ++  + +G Q QQ L  EC + +    ++++ F       K  + LP+++NKF E   M+  +FF RWK L    Q  Q V K+ + P++L   + +L G  + +L  +DP   N V +GI++  SQ+VG L+RLEPN   +++RLTVR++K+ V+R++ +++
Sbjct:    1 MAPVRGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKSPAPLTSAAQNNALVNNSHSKLNNSNA--NTDLLG--LSTPPSNNIGSGSNSNST---LIDVLGDMYGSNSNNNSSAV-----------YNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPLTNFNPVLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLTAECIEDYADAPTIEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQ-PLDLPGARNKLMGFGMQLLDQVDPNPDNMVCAGIIHTQSQQVGCLMRLEPNKQAQMFRLTVRASKETVTREICDLL 936

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BLAST of AP-2 complex subunit alpha vs. Ensembl Fly
Match: AP-2alpha (gene:FBgn0264855 transcript:FBtr0089489)

HSP 1 Score: 1170.22 bits (3026), Expect = 0.000e+0
Identity = 592/934 (63.38%), Postives = 726/934 (77.73%), Query Frame = 2

Query:   92 CKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPP-PDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQ-HPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI-LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            CKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKY+EKQIGYLFISVL+N + +L+ L++Q +K+DL SRNPV V LALQCIANIG+R+M E+F+ EIP+LLVSGDT+D VKQSAALCLL+L R++PD++   +WTSR+IHLLNDQHMGVVTAA SLI++LVKR+P+EYK CV+LAVSRLSRIVT+SYTDLQDYTYYFVPAPWLSVKLLRLLQNY P  ++A VR+RL E LE+IL+KAQEPPKSKKVQHSNAKNAVLFEAINLIIH D +PNLL+RACNQLGQFLS+RETNLRYLALESMC LATSEFSHE VKKHQE VI ++K E+DVSVRQ AVDLLYAMCDR NAEEIV EML+YLE+ADYSIREEMVLKVAIL+EKYATDY+WYVD ILNLIR+AGDYVSEEVW+RVIQIVINR +VQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGD RS+P +QF++LH+KYHLC+P TR LLLSTY+KFINLFPEI+  IQD+ +  SNLR+AD E+QQR  EYL LS +A+ DV+ATVLEEMPSF ERESSILA LK+KKP  +   E+   +   P    ++N+    N         A    DLLG   S    N   S S S  T   L+D+LG+ + S+ N N S+             N  K L+K++G+LFEN+ +QIG+KSEFR N+GRLG+FYGNK+   +T+F   L  S    + L + +  ++  + +G Q QQ L  EC + +    ++++ F       K  + LP+++NKF E   M+  +FF RWK L    Q  Q V K+ + P++L   + +L G  + +L  +DP   N V +GI++  SQ+VG L+RLEPN   +++RLTVR++K+ V+R++ +++
Sbjct:   34 CKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKSPAPLTSAAQNNALVNNSHSKLNNSNA--NTDLLG--LSTPPSNNIGSGSNSNST---LIDVLGDMYGSNSNNNSSAV-----------YNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPLTNFNPVLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLTAECIEDYADAPTIEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQ-PLDLPGARNKLMGFGMQLLDQVDPNPDNMVCAGIIHTQSQQVGCLMRLEPNKQAQMFRLTVRASKETVTREICDLL 948

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Fly
Match: AP-1gamma (gene:FBgn0030089 transcript:FBtr0333808)

HSP 1 Score: 228.409 bits (581), Expect = 9.286e-62
Identity = 173/591 (29.27%), Postives = 310/591 (52.45%), Query Frame = 2

Query:  122 INRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQ--NYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDV--QGYSAKTVFEALQ-APACHEN--MVKVGGYILGEFGNLI---AGDPRSSPQIQFQILHAKYHLCTP-----TTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSF 1840
            +N+E A IRS F+ +   D   + + + KLL+I +LG+   FG  E + L  S ++T+K+IGYL   +L++E  ++  L+   LK+DL+S     V LAL  +  I + EM  + A E+ RL+ S +T   +++ A LC  ++IR  P+L+      +R   LL++++ G++   V+LI  + + S +    +K  V   V  L  ++   Y+   D +   V  P+L VK+LRLL+   +  PD        +E +  IL++     ++ K    N  N +L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL +  LL T      AV++H+ T++  LK + DVS+R+RA++L +A+ +  N   +  E+L +LE AD   + +    + + +E+Y+    W++DT L+++  AG+YV ++V    IQ+V + S V  Q Y     +E+LQ A  C +   +++V  + +GE+G+L    A +       +  ++   Y   T      T++Q  L +  K      +  EEIQ ++ +  +  N D  +QQR +E+  L       +   +LE+MP+ 
Sbjct:   55 VNKECAYIRSTFREE---DSVWRCRNIAKLLYIHMLGYPAHFGQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMARDLASEVERLMKSPNTY--IRKKATLCAFRVIRRVPELMEIFLPATR--SLLSEKNHGILITGVTLITEMCENSSDTLMHFKKIVPNLVRILKNLILGGYSPEHDVSG--VSDPFLQVKILRLLRILGHNDPD-------ASEAMNDILAQVATNTETSK----NVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNT--LLRTVHADTSAVQRHRTTILECLK-DPDVSIRRRAMELSFALINAQNIRTMTKELLLFLEKADAEFKAQCSSGMILAAERYSPTTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLV-SSSPVPEQTYITNRFWESLQVANHCEDKQPLLQVAVWAIGEYGDLFMYGANEDEFERPTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTRLQQCVEEIQALITSFGSHLNVD--LQQRGVEFTQLFG-HYKHLRPPLLEKMPAM 618

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Fly
Match: AP-1gamma (gene:FBgn0030089 transcript:FBtr0071298)

HSP 1 Score: 228.409 bits (581), Expect = 9.286e-62
Identity = 173/591 (29.27%), Postives = 310/591 (52.45%), Query Frame = 2

Query:  122 INRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQ--NYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDV--QGYSAKTVFEALQ-APACHEN--MVKVGGYILGEFGNLI---AGDPRSSPQIQFQILHAKYHLCTP-----TTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSF 1840
            +N+E A IRS F+ +   D   + + + KLL+I +LG+   FG  E + L  S ++T+K+IGYL   +L++E  ++  L+   LK+DL+S     V LAL  +  I + EM  + A E+ RL+ S +T   +++ A LC  ++IR  P+L+      +R   LL++++ G++   V+LI  + + S +    +K  V   V  L  ++   Y+   D +   V  P+L VK+LRLL+   +  PD        +E +  IL++     ++ K    N  N +L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL +  LL T      AV++H+ T++  LK + DVS+R+RA++L +A+ +  N   +  E+L +LE AD   + +    + + +E+Y+    W++DT L+++  AG+YV ++V    IQ+V + S V  Q Y     +E+LQ A  C +   +++V  + +GE+G+L    A +       +  ++   Y   T      T++Q  L +  K      +  EEIQ ++ +  +  N D  +QQR +E+  L       +   +LE+MP+ 
Sbjct:   55 VNKECAYIRSTFREE---DSVWRCRNIAKLLYIHMLGYPAHFGQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMARDLASEVERLMKSPNTY--IRKKATLCAFRVIRRVPELMEIFLPATR--SLLSEKNHGILITGVTLITEMCENSSDTLMHFKKIVPNLVRILKNLILGGYSPEHDVSG--VSDPFLQVKILRLLRILGHNDPD-------ASEAMNDILAQVATNTETSK----NVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNT--LLRTVHADTSAVQRHRTTILECLK-DPDVSIRRRAMELSFALINAQNIRTMTKELLLFLEKADAEFKAQCSSGMILAAERYSPTTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLV-SSSPVPEQTYITNRFWESLQVANHCEDKQPLLQVAVWAIGEYGDLFMYGANEDEFERPTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTRLQQCVEEIQALITSFGSHLNVD--LQQRGVEFTQLFG-HYKHLRPPLLEKMPAM 618

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Fly
Match: AP-1gamma (gene:FBgn0030089 transcript:FBtr0071295)

HSP 1 Score: 228.409 bits (581), Expect = 9.286e-62
Identity = 173/591 (29.27%), Postives = 310/591 (52.45%), Query Frame = 2

Query:  122 INRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQ--NYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDV--QGYSAKTVFEALQ-APACHEN--MVKVGGYILGEFGNLI---AGDPRSSPQIQFQILHAKYHLCTP-----TTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSF 1840
            +N+E A IRS F+ +   D   + + + KLL+I +LG+   FG  E + L  S ++T+K+IGYL   +L++E  ++  L+   LK+DL+S     V LAL  +  I + EM  + A E+ RL+ S +T   +++ A LC  ++IR  P+L+      +R   LL++++ G++   V+LI  + + S +    +K  V   V  L  ++   Y+   D +   V  P+L VK+LRLL+   +  PD        +E +  IL++     ++ K    N  N +L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL +  LL T      AV++H+ T++  LK + DVS+R+RA++L +A+ +  N   +  E+L +LE AD   + +    + + +E+Y+    W++DT L+++  AG+YV ++V    IQ+V + S V  Q Y     +E+LQ A  C +   +++V  + +GE+G+L    A +       +  ++   Y   T      T++Q  L +  K      +  EEIQ ++ +  +  N D  +QQR +E+  L       +   +LE+MP+ 
Sbjct:   55 VNKECAYIRSTFREE---DSVWRCRNIAKLLYIHMLGYPAHFGQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMARDLASEVERLMKSPNTY--IRKKATLCAFRVIRRVPELMEIFLPATR--SLLSEKNHGILITGVTLITEMCENSSDTLMHFKKIVPNLVRILKNLILGGYSPEHDVSG--VSDPFLQVKILRLLRILGHNDPD-------ASEAMNDILAQVATNTETSK----NVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNT--LLRTVHADTSAVQRHRTTILECLK-DPDVSIRRRAMELSFALINAQNIRTMTKELLLFLEKADAEFKAQCSSGMILAAERYSPTTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLV-SSSPVPEQTYITNRFWESLQVANHCEDKQPLLQVAVWAIGEYGDLFMYGANEDEFERPTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTRLQQCVEEIQALITSFGSHLNVD--LQQRGVEFTQLFG-HYKHLRPPLLEKMPAM 618

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BLAST of AP-2 complex subunit alpha vs. Ensembl Zebrafish
Match: ap2a1 (adaptor related protein complex 2 subunit alpha 1 [Source:ZFIN;Acc:ZDB-GENE-090302-2])

HSP 1 Score: 1212.98 bits (3137), Expect = 0.000e+0
Identity = 611/971 (62.92%), Postives = 737/971 (75.90%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXX-------XXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTS--DLLLDILGNGFDSDINENK--SSTNPITLEQS------ESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTEL-CNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L + +PDLV   +WTSRV+HLLNDQHMGVVTAA+SLI  L +++P+E+K CVSLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLS KLLRLLQ YPPP+D  V+ RL ECLE+IL+KAQEPPKSKKVQHSNAKNA+LFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EMLSYLE+ADYSIREEMVLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLS Y+KFINLFPE K  IQ++L++DS +RN+DVE+QQR +EYL LS IA+ DV+ATVLEEMP F ERESSILAK                EG+           +   ++  T   S A+   P+    DLLG         +T  + ++ P S   LL+D+     ++ +N++   SS  P  + +       ES+E   K + K++G+LFEN  +QIGIKSE+R N+GR+ +FYGNK+  Q   F T + C       L +   P++  I  G Q QQ +NIEC   F +   L + F        + L LP+TINKF +   M  + FFQRWK L QP QE Q + K+    M+  V++ +L GL +++L N+DP   NFV +G++   +Q+VG LLRLEPN   ++YRLT+RS+KD VS+++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMCLALHCIANVGSREMAEAFAGEIPRILVAGDTMDSVKQSAALCLLRLYKTSPDLVLMGEWTSRVVHLLNDQHMGVVTAAISLITCLSQKNPDEFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSCKLLRLLQCYPPPEDGAVKGRLVECLETILNKAQEPPKSKKVQHSNAKNAILFEAISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVAEMLSYLETADYSIREEMVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPLVQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPETKSTIQEVLRSDSQIRNSDVELQQRAVEYLKLSSIASTDVLATVLEEMPPFPERESSILAKLKKKKGPGAVSVNELEEGKREGGELNGGGGERGGDN-STIAASNASTPSPS---ADLLG--------LRTGPQVSAAPPSAGSLLVDVFS---EAGVNDDGFLSSAPPSAVSEDAAPPLPESNELLNKFVCKNNGVLFENQLLQIGIKSEYRQNLGRMYLFYGNKTSVQFVTFTTTVSCPGELHPQLNVQAKPVEPLIEGGAQVQQVINIECLGDFCEAPLLNIKFRYGGALQNLSLKLPVTINKFFQPTEMASHDFFQRWKQLSQPQQEAQKIFKASHA-MDTEVIKAKLLGLGMALLENVDPNPENFVCAGVIQTKAQQVGSLLRLEPNAQAQMYRLTLRSSKDTVSKRLCELL 955

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Zebrafish
Match: ap1g1 (adaptor related protein complex 1 subunit gamma 1 [Source:ZFIN;Acc:ZDB-GENE-030131-3187])

HSP 1 Score: 263.077 bits (671), Expect = 2.376e-74
Identity = 176/600 (29.33%), Postives = 324/600 (54.00%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPQIQ------FQILHAKY--HLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMP 1834
             I  IR  +++  E + I +E A IRS F+ +   D   + + V KLL++ +LG+   FG  E + L+ S K+T+K+IGYL   +L++E  ++  L+   +K+DL+        LAL  +  +G+ EM  + A E+ +LL + ++   +++ AALC + +IR  P+L+    +     +LL++++ GV+  +V L+  + +RSP+    ++  V   V  L  ++ S Y+   D +   +  P+L V++LRLL+     DD       +E +  IL++     ++ K    N  NA+L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL S  LL T +  H AV++H+ T++  LK + DVS+++RA++L +A+ + NN   ++ E+L +L+S D   + +    + + +EKYA    W++DTI+ ++  AG YV ++    +IQ++ N  ++  Y+ + +++AL      + +V+V  + +GE+G+ L++G       IQ        +L      +L  P TR   L+  +K    F  +    + +    S++   DVE+QQR +EY  L K   D +   +LE MP
Sbjct:   10 LIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPATKNLLSEKNHGVLHTSVVLLTEMCERSPDMLSHFRKLVPQLVRILKNLIMSGYSPEHDVS--GISDPFLQVRILRLLRILGKGDDDS-----SEAMNDILAQVATNTETSK----NVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTS--LLKTVQTDHNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCDPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDSVPNLIQLITNSVEMHAYTVQRLYKALLDDISQQPLVQVASWCIGEYGDLLVSGQCEEEEPIQVSEDEVLDVLEGLLVSNLSAPVTRGYSLTAIMKLSTRFSSVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRPALLERMP 584

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Zebrafish
Match: ap1g2 (adaptor related protein complex 1 subunit gamma 2 [Source:ZFIN;Acc:ZDB-GENE-030616-587])

HSP 1 Score: 255.373 bits (651), Expect = 7.470e-72
Identity = 175/600 (29.17%), Postives = 324/600 (54.00%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPQIQF---QILHA-----KYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMP 1834
             I  IR+ +++  E   I +E A IR++F+     D  ++   + KLL++ +LG+   FG  E V L+ S +Y+EK+IGYL   +L++E  +   L+   +K+DLS  +    +LAL  +A +G+ EM  + A EI RLL +  +   +K+ A LC + +IR  P+L     +T     LL++++ GV+  AV LI  L +R+ E   +++  V   V+ +  +VTSSY+   ++    +  P+L V++LRLL+     +D+      ++ +  +L++      S K     A +AVL+E +  I+ ++ +  L + A N LG+FL + + N+RY+++ S+  +  ++  H AV++H+ T++  LK ++D SV++RA++L  A+    N   ++ E+L +L S    +R +    +   +E+Y+    W++DTIL+++  AG  V +E    +IQ++   S++  Y+   ++ AL      +++V+V  + +GE+G+ L+ G+      +Q     +L A     + H+  P TR   L+  +K      +  + I+ I+    +    D+E+QQR +EY  L K   D + A VLE MP
Sbjct:   10 MIRVIRSARTQGEERGIIQKECAEIRAQFR---QTDNGERSHSLAKLLYVHMLGYPAHFGQMECVRLIASPRYSEKRIGYLGAMMLLDEKQDASLLITNSIKNDLSHSSQYVQSLALCTLACMGSSEMCRDLAPEIERLLRASTSY--IKKKATLCAVHIIRKVPELAEL--FTPSARSLLSEKNHGVLHGAVVLITELCERNAETLDKFRKAVPELVTIMKGLVTSSYSP--EHNVAGISDPFLQVRILRLLRILGHNNDSA-----SDAMNDLLAQVATNTDSSK----TAGSAVLYETVLTIMDINSESGLRVLAVNILGRFLLNNDRNIRYISMTSLQKIVQTD--HNAVQRHRGTIVDCLK-DQDTSVKRRALELSLALVSPVNIRSMMKELLIFLSSCPVELRSQTASGIFNAAERYSPSKRWHIDTILHVLTTAGGDVRDETVPNLIQLITTASELHCYTVHKLYRALVKDISQQSLVQVACWCIGEYGDLLLKGECEEIEPVQVTEDDVLDALETVLQSHMSAPATRGFALTATMKLSTRITDNVDRIRSIVSIYGSC--IDLELQQRAVEYNALFK-KYDHMRAAVLERMP 585

[Close]

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPQIQF---QILHA-----KYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMP 1834
             I  IR+ +++  E   I +E A IR++F+     D  ++   + KLL++ +LG+   FG  E V L+ S +Y+EK+IGYL   +L++E  +   L+   +K+DLS  +    +LAL  +A +G+ EM  + A EI RLL +  +   +K+ A LC + +IR  P+L     +T     LL++++ GV+  AV LI  L +R+ E   +++  V   V+ +  +VTSSY+   ++    +  P+L V++LRLL+     +D+      ++ +  +L++      S K     A +AVL+E +  I+ ++ +  L + A N LG+FL + + N+RY+++ S+  +  ++  H AV++H+ T++  LK ++D SV++RA++L  A+    N   ++ E+L +L S    +R +    +   +E+Y+    W++DTIL+++  AG  V +E    +IQ++   S++  Y+   ++ AL      +++V+V  + +GE+G+ L+ G+      +Q     +L A     + H+  P TR   L+  +K      +  + I+ I+    +    D+E+QQR +EY  L K   D + A VLE MP
Sbjct:   10 MIRVIRSARTQGEERGIIQKECAEIRAQFR---QTDNGERSHSLAKLLYVHMLGYPAHFGQMECVRLIASPRYSEKRIGYLGAMMLLDEKQDASLLITNSIKNDLSHSSQYVQSLALCTLACMGSSEMCRDLAPEIERLLRASTSY--IKKKATLCAVHIIRKVPELAEL--FTPSARSLLSEKNHGVLHGAVVLITELCERNAETLDKFRKAVPELVTIMKGLVTSSYSP--EHNVAGISDPFLQVRILRLLRILGHNNDSA-----SDAMNDLLAQVATNTDSSK----TAGSAVLYETVLTIMDINSESGLRVLAVNILGRFLLNNDRNIRYISMTSLQKIVQTD--HNAVQRHRGTIVDCLK-DQDTSVKRRALELSLALVSPVNIRSMMKELLIFLSSCPVELRSQTASGIFNAAERYSPSKRWHIDTILHVLTTAGGDVRDETVPNLIQLITTASELHCYTVHKLYRALVKDISQQSLVQVACWCIGEYGDLLLKGECEEIEPVQVTEDDVLDALETVLQSHMSAPATRGFALTATMKLSTRITDNVDRIRSIVSIYGSC--IDLELQQRAVEYNALFK-KYDHMRAAVLERMP 585

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Zebrafish
Match: ap2a1 (adaptor related protein complex 2 subunit alpha 1 [Source:ZFIN;Acc:ZDB-GENE-090302-2])

HSP 1 Score: 196.438 bits (498), Expect = 1.054e-55
Identity = 106/277 (38.27%), Postives = 161/277 (58.12%), Query Frame = 2

Query: 2057 TNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTEL-CNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
             ++ ST  P++DLL    G    +      S    +  E   +D+ +L+ + K++G+LFEN  +QIGIKSE+R N+GR+ +FYGNK+  Q   F T + C       L +   P++  I  G Q QQ +NIEC   F +   L + F        + L LP+TINKF +   M  + FFQRWK L QP QE Q + K+    M+  V++ +L GL +++L N+DP   NFV +G++   +Q+VG LLRLEPN   ++YRLT+RS+KD VS+++  ++
Sbjct:   26 ASNASTPSPSADLLGLRTGPQVSAAPPSAGSLLVDVFSEAGVNDDGFLRFVCKNNGVLFENQLLQIGIKSEYRQNLGRMYLFYGNKTSVQFVTFTTTVSCPGELHPQLNVQAKPVEPLIEGGAQVQQVINIECLGDFCEAPLLNIKFRYGGALQNLSLKLPVTINKFFQPTEMASHDFFQRWKQLSQPQQEAQKIFKASHA-MDTEVIKAKLLGLGMALLENVDPNPENFVCAGVIQTKAQQVGSLLRLEPNAQAQMYRLTLRSSKDTVSKRLCELL 301

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BLAST of AP-2 complex subunit alpha vs. Ensembl Xenopus
Match: ap2a2 (adaptor related protein complex 2 subunit alpha 2 [Source:NCBI gene;Acc:407867])

HSP 1 Score: 1237.25 bits (3200), Expect = 0.000e+0
Identity = 613/957 (64.05%), Postives = 741/957 (77.43%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLD--TQNDSPATKEEPAIQEVDLLG-GLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTEL-CNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L R +PDLV  ++WTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LII+ D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLS Y+KFINLFPEIK  IQD+L++DS LRNADVE+QQR +EYL LS IA++D++ATVLEEMP F ERESSI       K    +G   +   +    + S + L+  T++   +T   P+    DLLG G  S S    +++ +T+     LL+D+               + P+    +E+D+N+ + + K++G+LFEN  +QIGIKSEFR N+GR+ IF+GNK   Q  +F T L C  P     +L   P +  I  G Q QQ +N+EC Q F     L + F        + + LPIT+NKF +   M+   FFQRWK L  P QE Q + K+ K PM+  + + RL G   +V+ N+DP  SN+VA+GI+   +++VG LLRLEPN   ++YRLT+R++K+ VS+ + +++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMGLALHCIANVGSREMAEAFAGEIPRILVAGDTMDSVKQSAALCLLRLYRTSPDLVLTNEWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIYHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPEIKTTIQDVLRSDSQLRNADVELQQRAVEYLRLSSIASNDILATVLEEMPPFPERESSI-----LAKLKKKKGPSTVTDLEETKKEKSNSDLNGITEHAPLSTTSTPS-PSADLLGLGAASGS----SSTPTTAPSAGSLLVDVFA-----------EPSLPVAAVTTEADDNFPRFICKNNGVLFENQLLQIGIKSEFRQNLGRMFIFFGNKMSSQFQNFTTTLICVLPKRASFRLPSKPAEPTIDGGAQVQQVVNVECVQEFTDLPLLNIQFRYGGAFQNVSVKLPITLNKFFQPTEMNSQDFFQRWKQLSSPNQEVQKIFKA-KNPMDTDITKARLIGFGPAVMDNVDPNPSNYVAAGIIQAKTRQVGCLLRLEPNEQAQMYRLTIRTSKEEVSQTLCDLL 935

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Xenopus
Match: ap2a2 (adaptor related protein complex 2 subunit alpha 2 [Source:NCBI gene;Acc:407867])

HSP 1 Score: 1231.08 bits (3184), Expect = 0.000e+0
Identity = 611/956 (63.91%), Postives = 738/956 (77.20%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLD--TQNDSPATKEEPAIQEVDLLG-GLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L R +PDLV  ++WTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LII+ D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLS Y+KFINLFPEIK  IQD+L++DS LRNADVE+QQR +EYL LS IA++D++ATVLEEMP F ERESSI       K    +G   +   +    + S + L+  T++   +T   P+    DLLG G  S S    +++ +T+     LL+D+               + P+    +E+D+N+ + + K++G+LFEN  +QIGIKSEFR N+GR+ IF+GNK   Q  +F T L       I      P +  I  G Q QQ +N+EC Q F     L + F        + + LPIT+NKF +   M+   FFQRWK L  P QE Q + K+ K PM+  + + RL G   +V+ N+DP  SN+VA+GI+   +++VG LLRLEPN   ++YRLT+R++K+ VS+ + +++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMGLALHCIANVGSREMAEAFAGEIPRILVAGDTMDSVKQSAALCLLRLYRTSPDLVLTNEWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIYHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPEIKTTIQDVLRSDSQLRNADVELQQRAVEYLRLSSIASNDILATVLEEMPPFPERESSI-----LAKLKKKKGPSTVTDLEETKKEKSNSDLNGITEHAPLSTTSTPS-PSADLLGLGAASGS----SSTPTTAPSAGSLLVDVFA-----------EPSLPVAAVTTEADDNFPRFICKNNGVLFENQLLQIGIKSEFRQNLGRMFIFFGNKMSSQFQNFTTTLIYGALAGIELRTQQPAEPTIDGGAQVQQVVNVECVQEFTDLPLLNIQFRYGGAFQNVSVKLPITLNKFFQPTEMNSQDFFQRWKQLSSPNQEVQKIFKA-KNPMDTDITKARLIGFGPAVMDNVDPNPSNYVAAGIIQAKTRQVGCLLRLEPNEQAQMYRLTIRTSKEEVSQTLCDLL 934

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Xenopus
Match: ap2a2 (adaptor related protein complex 2 subunit alpha 2 [Source:NCBI gene;Acc:407867])

HSP 1 Score: 1226.46 bits (3172), Expect = 0.000e+0
Identity = 610/957 (63.74%), Postives = 737/957 (77.01%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDS---PATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTS-DLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L R +PDLV  ++WTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LII+ D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLS Y+KFINLFPEIK  IQD+L++DS LRNADVE+QQR +EYL LS IA++D++ATVLEEMP F ERESSI       K    +G   +   +    + S + L+   +S    A+         DLLG        + ++S  T+ P++  LL+D+               + P+    +E+D+N+ + + K++G+LFEN  +QIGIKSEFR N+GR+ IF+GNK   Q  +F T L  S      +L   P +  I  G Q QQ +N+EC Q F     L + F        + + LPIT+NKF +   M+   FFQRWK L  P QE Q + K+ K PM+  + + RL G   +V+ N+DP  SN+VA+GI+   +++VG LLRLEPN   ++YRLT+R++K+ VS+ + +++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMGLALHCIANVGSREMAEAFAGEIPRILVAGDTMDSVKQSAALCLLRLYRTSPDLVLTNEWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIYHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPEIKTTIQDVLRSDSQLRNADVELQQRAVEYLRLSSIASNDILATVLEEMPPFPERESSI-----LAKLKKKKGPSTVTDLEETKKEKSNSDLNGITESVLMAASTSSTPSPSADLLG----LGAASGSSSTPTTAPSAGSLLVDVFA-----------EPSLPVAAVTTEADDNFPRFICKNNGVLFENQLLQIGIKSEFRQNLGRMFIFFGNKMSSQFQNFTTTLICSD-----ELSSKPAEPTIDGGAQVQQVVNVECVQEFTDLPLLNIQFRYGGAFQNVSVKLPITLNKFFQPTEMNSQDFFQRWKQLSSPNQEVQKIFKA-KNPMDTDITKARLIGFGPAVMDNVDPNPSNYVAAGIIQAKTRQVGCLLRLEPNEQAQMYRLTIRTSKEEVSQTLCDLL 931

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Xenopus
Match: ap2a2 (adaptor related protein complex 2 subunit alpha 2 [Source:NCBI gene;Acc:407867])

HSP 1 Score: 1222.22 bits (3161), Expect = 0.000e+0
Identity = 613/965 (63.52%), Postives = 739/965 (76.58%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQND-----SPATKEEPAIQEVDLLG-GLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLK------LLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L R +PDLV  ++WTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LII+ D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLS Y+KFINLFPEIK  IQD+L++DS LRNADVE+QQR +EYL LS IA++D++ATVLEEMP F ERESSI       K    +G   +   +    + S + L+   D     +P+T    A    DLLG G  S S    +++ +T+     LL+D+               + P+    +E+D+N+ +       + K++G+LFEN  +QIGIKSEFR N+GR+ IF+GNK   Q  +F T L  S      +L   P +  I  G Q QQ +N+EC Q F     L + F        + + LPIT+NKF +   M+   FFQRWK L  P QE Q + K+ K PM+  + + RL G   +V+ N+DP  SN+VA+GI+   +++VG LLRLEPN   ++YRLT+R++K+ VS+ + +++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMGLALHCIANVGSREMAEAFAGEIPRILVAGDTMDSVKQSAALCLLRLYRTSPDLVLTNEWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIYHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPEIKTTIQDVLRSDSQLRNADVELQQRAVEYLRLSSIASNDILATVLEEMPPFPERESSI-----LAKLKKKKGPSTVTDLEETKKEKSNSDLNGITDCSFTIAPSTPSPSA----DLLGLGAASGS----SSTPTTAPSAGSLLVDVFA-----------EPSLPVAAVTTEADDNFPRYQEQHQFICKNNGVLFENQLLQIGIKSEFRQNLGRMFIFFGNKMSSQFQNFTTTLICSD-----ELSSKPAEPTIDGGAQVQQVVNVECVQEFTDLPLLNIQFRYGGAFQNVSVKLPITLNKFFQPTEMNSQDFFQRWKQLSSPNQEVQKIFKA-KNPMDTDITKARLIGFGPAVMDNVDPNPSNYVAAGIIQAKTRQVGCLLRLEPNEQAQMYRLTIRTSKEEVSQTLCDLL 935

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Xenopus
Match: ap2a2 (adaptor related protein complex 2 subunit alpha 2 [Source:NCBI gene;Acc:407867])

HSP 1 Score: 1221.45 bits (3159), Expect = 0.000e+0
Identity = 607/949 (63.96%), Postives = 736/949 (77.56%), Query Frame = 2

Query:   53 MRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLD--TQNDSPATKEEPAIQEVDLLG-GLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDL--NPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L R +PDLV  ++WTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LII+ D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLS Y+KFINLFPEIK  IQD+L++DS LRNADVE+QQR +EYL LS IA++D++ATVLEEMP F ERESSI       K    +G   +   +    + S + L+  T++   +T   P+    DLLG G  S S    +++ +T+     LL+D+               + P+    +E+D+N+ + + K++G+LFEN  +QIGIKSEFR N+GR+ IF+GNK   Q  +F T L  S   ++  L L   P +  I  G Q QQ +N+EC Q F     L + F        + + LPIT+NKF +   M+   FFQRWK L  P QE Q + K+ K PM+  + + RL G   +V+ N+DP  SN+VA+GI+   +++VG LLRLEPN   ++YRLT+R++K+ VS+ + +++
Sbjct:    1 MRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMGLALHCIANVGSREMAEAFAGEIPRILVAGDTMDSVKQSAALCLLRLYRTSPDLVLTNEWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIYHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPEIKTTIQDVLRSDSQLRNADVELQQRAVEYLRLSSIASNDILATVLEEMPPFPERESSI-----LAKLKKKKGPSTVTDLEETKKEKSNSDLNGITEHAPLSTTSTPS-PSADLLGLGAASGS----SSTPTTAPSAGSLLVDVFA-----------EPSLPVAAVTTEADDNFPRFICKNNGVLFENQLLQIGIKSEFRQNLGRMFIFFGNKMSSQFQNFTTTLICSDELSVGDLCLISKPAEPTIDGGAQVQQVVNVECVQEFTDLPLLNIQFRYGGAFQNVSVKLPITLNKFFQPTEMNSQDFFQRWKQLSSPNQEVQKIFKA-KNPMDTDITKARLIGFGPAVMDNVDPNPSNYVAAGIIQAKTRQVGCLLRLEPNEQAQMYRLTIRTSKEEVSQTLCDLL 927

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BLAST of AP-2 complex subunit alpha vs. Ensembl Mouse
Match: Ap2a2 (adaptor-related protein complex 2, alpha 2 subunit [Source:MGI Symbol;Acc:MGI:101920])

HSP 1 Score: 1224.92 bits (3168), Expect = 0.000e+0
Identity = 611/968 (63.12%), Postives = 741/968 (76.55%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLL-LDIL-----------GNGFDSDI-NENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L R +PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPPD A VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS L+NADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+  K    T  D   TK E   + +D+ GG      P  T++ ST  P++DLL L  +           G G   D+ +++ S+  P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C     T L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE Q++ K+ K PM+  + + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++KD VS+++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPA-VRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEETKRE---RSIDVNGG--PEPVPASTSAASTPSPSADLLGLGAVPPAPTGPPPSSGGGLLVDVFSDSASAVAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVDPTVDGGAQVQQVVNIECISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKA-KHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELL 934

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BLAST of AP-2 complex subunit alpha vs. Ensembl Mouse
Match: Ap2a1 (adaptor-related protein complex 2, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:101921])

HSP 1 Score: 1191.79 bits (3082), Expect = 0.000e+0
Identity = 599/963 (62.20%), Postives = 723/963 (75.08%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQND-SPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNG------FDSDINENKSSTNP--ITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDF-GTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA +IPR+LV+GD++DSVKQSAALCLL+L +A+PDLV   +WT+RV+HLLNDQHMGVVTAAVSLI  L K++P+++K C+SLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+DA V+ RL ECLE++L+KAQEPPKSKKVQHSNAKNA+LFE I+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H +TVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EML YLE+ADY+IREE+VLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RV+QIV NR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLSTY+KFINLFPE K  IQ +L+  S LRNADVE+QQR +EYLTLS +A+ DV+ATVLEEMP F ERESSI       K    +G    +         S N ++   + +P+T   P+    DLLG      +     +   +    +LL+D+  +G            E   S  P  I     E+DE   K + K+SG+LFEN  +QIG+KSEFR N+GR+ +FYGNK+  Q  +F  T +      T L +    + + +  G Q QQ LNIEC + F     L V F     +  + L LP+TINKF +   M    FFQRWK L  P QE Q + K+   PM+  V + +L G   ++L N+DP   NFV +GI+   + +VG LLRLEPN   ++YRLT+R++K+ VSR +  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSI-----LAKLKRKKGPGAASALDDSRRDTSSNDINGGVEPTPSTVSTPS-PSADLLG-----LRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFLSPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFLPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGTAQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKA-NHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELL 951

[Close]

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQND-SPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNG------FDSDINENKSSTNP--ITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDF-GTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA +IPR+LV+GD++DSVKQSAALCLL+L +A+PDLV   +WT+RV+HLLNDQHMGVVTAAVSLI  L K++P+++K C+SLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+DA V+ RL ECLE++L+KAQEPPKSKKVQHSNAKNA+LFE I+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H +TVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EML YLE+ADY+IREE+VLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RV+QIV NR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLSTY+KFINLFPE K  IQ +L+  S LRNADVE+QQR +EYLTLS +A+ DV+ATVLEEMP F ERESSI       K    +G    +         S N ++   + +P+T   P+    DLLG      +     +   +    +LL+D+  +G            E   S  P  I     E+DE   K + K+SG+LFEN  +QIG+KSEFR N+GR+ +FYGNK+  Q  +F  T +      T L +    + + +  G Q QQ LNIEC + F     L V F     +  + L LP+TINKF +   M    FFQRWK L  P QE Q + K+   PM+  V + +L G   ++L N+DP   NFV +GI+   + +VG LLRLEPN   ++YRLT+R++K+ VSR +  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSI-----LAKLKRKKGPGAASALDDSRRDTSSNDINGGVEPTPSTVSTPS-PSADLLG-----LRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFLSPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFLPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGTAQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKA-NHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELL 951

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Mouse
Match: Ap2a1 (adaptor-related protein complex 2, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:101921])

HSP 1 Score: 1185.63 bits (3066), Expect = 0.000e+0
Identity = 600/986 (60.85%), Postives = 729/986 (73.94%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQND-SPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNG--------------FDSDINENKSSTNPITLEQS-----------------ESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDF-GTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA +IPR+LV+GD++DSVKQSAALCLL+L +A+PDLV   +WT+RV+HLLNDQHMGVVTAAVSLI  L K++P+++K C+SLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+DA V+ RL ECLE++L+KAQEPPKSKKVQHSNAKNA+LFE I+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H +TVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EML YLE+ADY+IREE+VLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RV+QIV NR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLSTY+KFINLFPE K  IQ +L+  S LRNADVE+QQR +EYLTLS +A+ DV+ATVLEEMP F ERESSI       K    +G    +         S N ++   + +P+T   P+    DLLG      +     +   +    +LL+D+  +G              F S++ E  +  +P+ L                    E+DE   K + K+SG+LFEN  +QIG+KSEFR N+GR+ +FYGNK+  Q  +F  T +      T L +    + + +  G Q QQ LNIEC + F     L V F     +  + L LP+TINKF +   M    FFQRWK L  P QE Q + K+   PM+  V + +L G   ++L N+DP   NFV +GI+   + +VG LLRLEPN   ++YRLT+R++K+ VSR +  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSI-----LAKLKRKKGPGAASALDDSRRDTSSNDINGGVEPTPSTVSTPS-PSADLLG-----LRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFLSEL-EPPAPESPMALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFLPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGTAQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKA-NHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELL 973

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Mouse
Match: Ap2a1 (adaptor-related protein complex 2, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:101921])

HSP 1 Score: 1185.63 bits (3066), Expect = 0.000e+0
Identity = 600/986 (60.85%), Postives = 729/986 (73.94%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQND-SPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNG--------------FDSDINENKSSTNPITLEQS-----------------ESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDF-GTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA +IPR+LV+GD++DSVKQSAALCLL+L +A+PDLV   +WT+RV+HLLNDQHMGVVTAAVSLI  L K++P+++K C+SLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+DA V+ RL ECLE++L+KAQEPPKSKKVQHSNAKNA+LFE I+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H +TVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EML YLE+ADY+IREE+VLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RV+QIV NR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLSTY+KFINLFPE K  IQ +L+  S LRNADVE+QQR +EYLTLS +A+ DV+ATVLEEMP F ERESSI       K    +G    +         S N ++   + +P+T   P+    DLLG      +     +   +    +LL+D+  +G              F S++ E  +  +P+ L                    E+DE   K + K+SG+LFEN  +QIG+KSEFR N+GR+ +FYGNK+  Q  +F  T +      T L +    + + +  G Q QQ LNIEC + F     L V F     +  + L LP+TINKF +   M    FFQRWK L  P QE Q + K+   PM+  V + +L G   ++L N+DP   NFV +GI+   + +VG LLRLEPN   ++YRLT+R++K+ VSR +  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSI-----LAKLKRKKGPGAASALDDSRRDTSSNDINGGVEPTPSTVSTPS-PSADLLG-----LRAAPPPAAPPAPVGGNLLVDVFSDGPTAQPSLGPTPEEAFLSEL-EPPAPESPMALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFLPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGTAQSLTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPLQEAQKIFKA-NHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELL 973

[Close]

BLAST of AP-2 complex subunit alpha vs. UniProt/SwissProt
Match: sp|P17427|AP2A2_MOUSE (AP-2 complex subunit alpha-2 OS=Mus musculus OX=10090 GN=Ap2a2 PE=1 SV=2)

HSP 1 Score: 1224.92 bits (3168), Expect = 0.000e+0
Identity = 611/968 (63.12%), Postives = 741/968 (76.55%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLL-LDIL-----------GNGFDSDI-NENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L R +PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPPD A VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS L+NADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+  K    T  D   TK E   + +D+ GG      P  T++ ST  P++DLL L  +           G G   D+ +++ S+  P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C     T L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE Q++ K+ K PM+  + + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++KD VS+++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPA-VRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEETKRE---RSIDVNGG--PEPVPASTSAASTPSPSADLLGLGAVPPAPTGPPPSSGGGLLVDVFSDSASAVAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVDPTVDGGAQVQQVVNIECISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKA-KHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELL 934

[Close]

BLAST of AP-2 complex subunit alpha vs. UniProt/SwissProt
Match: sp|P18484|AP2A2_RAT (AP-2 complex subunit alpha-2 OS=Rattus norvegicus OX=10116 GN=Ap2a2 PE=1 SV=3)

HSP 1 Score: 1223.38 bits (3164), Expect = 0.000e+0
Identity = 610/968 (63.02%), Postives = 741/968 (76.55%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLL-LDIL-----------GNGFDSDI-NENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KG+ MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L R +PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPPD A VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS L+NADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+  K    T  D   TK E   + +D+ GG      P  T++ ST  P++DLL L  +           G G   D+ +++ S+  P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C     T L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE Q++ K+ K PM+  + + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++KD VS+++  ++
Sbjct:    1 MPAVSKGEGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPA-VRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEETKRE---RSIDVNGG--PEPVPASTSAASTPSPSADLLGLGAVPPAPTGPPPSSGGGLLVDVFSDSASAVAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVDPTVDGGAQVQQVINIECISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKA-KHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELL 934

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BLAST of AP-2 complex subunit alpha vs. UniProt/SwissProt
Match: sp|Q0VCK5|AP2A2_BOVIN (AP-2 complex subunit alpha-2 OS=Bos taurus OX=9913 GN=AP2A2 PE=1 SV=1)

HSP 1 Score: 1216.45 bits (3146), Expect = 0.000e+0
Identity = 605/970 (62.37%), Postives = 738/970 (76.08%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQE--VDLLGGLFSYSQP--NQTNSKSTSQPTSDLL-----------LDILGNGFDSDI-NENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L RA+PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+L+ H D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP  QF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS L+NADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+ K     +  S  T  E A +E   D+ GG     +P    T++ ST  P++DLL                 G   D+ +++ S+  P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C+      L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE QS+ K+ K PM+  V + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++++ VS+++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLHRASPDLVPVGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLEAILNKAQEPPKSKKVQHSNAKNAVLFEAISLVTHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLTQFHLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKGTIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKK----KGPSTVTDLEEAKRERSADVNGG----PEPALASTSAVSTPSPSADLLGLGAAPPVPAGPPPSSGGLLVDVFSDSPSAAAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQANLSLQTKPVDPTVDGGAQVQQAVNIECVSDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQSIFKA-KHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTRTAQIGCLLRLEPNLQAQMYRLTLRTSRETVSQRLCELL 934

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BLAST of AP-2 complex subunit alpha vs. UniProt/SwissProt
Match: sp|Q29N38|AP2A_DROPS (AP-2 complex subunit alpha OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=alpha-Adaptin PE=3 SV=1)

HSP 1 Score: 1209.9 bits (3129), Expect = 0.000e+0
Identity = 609/959 (63.50%), Postives = 746/959 (77.79%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPP-PDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQEL-----IAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI-LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            M  V+GD MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKY+EKQIGYLFISVL+N + +L+ L++Q +K+DL SRNPV V LALQCIANIG+R+M E+F+ EIP+LLVSGDT+D VKQSAALCLL+L R++PD++   +WTSR+IHLLNDQHMGVVTAA SLI++LVK +P+EYK CV+LAVSRLSRIVT+SYTDLQDYTYYFVPAPWLSVKLLRLLQNY P  ++A VR+RL E LE+IL+KAQEPPKSKKVQHSNAKNAVLFEAINLIIH D +PNLL+RACNQLGQFLS+RETNLRYLALESMC LATSEFSHE VKKHQE VI ++K E+DVSVRQ AVDLLYAMCDR NAEEIV EML+YLE+ADYSIREEMVLKVAIL+EKYATDY+WYVD ILNLIR+AGDYVSEEVW+RVIQIVINR +VQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGD RS+P +QF++LH+KYHLC+P TR LLLSTY+KFINLFPEI+  IQD+ +  SNLR+AD E+QQR  EYL LS +A+ DV+ATVLEEMPSF ERESSILA LK+KKP  +   E+      AP   P   + +N++   N         A    DLLG     S P   N  S S  T   L+D+LG+ + S+ N             S +  N  K L+K++G+LFEN+ +QIG+KSEFR N+GRLG+FYGNK+   +++F   L  S   T+ L + +  ++  + +G Q QQ L  EC + +    ++++ F       K  + LP+++NKF E   M+  +FF RWK L    Q  Q V K+ + P++L   + +L G  + +L ++DP   N V +GI++  SQ+VG L+RLEPN   +++RLTVR++K+ V+R++ +++
Sbjct:    1 MAPVRGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKCNPDEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKSPAPTSGP-GSVLQNNVHVNNSHSKLNNSNA--NTDLLG----LSTPPANNVGSNSNST---LIDVLGDIYGSNNN-------------SSAVYNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPLSNFNPVLQWSAEETLKLNVQMKAVEPTLEAGAQIQQLLTAECIEDYADAPTIEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQ-PLDLPGARNKLMGFGMQLLDSVDPNPDNMVCAGIIHTQSQQVGCLMRLEPNKQAQMFRLTVRASKETVTREICDLL 935

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BLAST of AP-2 complex subunit alpha vs. UniProt/SwissProt
Match: sp|O94973|AP2A2_HUMAN (AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2)

HSP 1 Score: 1208.74 bits (3126), Expect = 0.000e+0
Identity = 606/971 (62.41%), Postives = 735/971 (75.70%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSD--------------INENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFG-TELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIES 2890
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SN+YTEKQIGYLFISVL+N +  L+ L+   +K+DL+SRNP F+ LAL CIA++G+REM E FA EIP++LV+GDT+DSVKQSAALCLL+L R +PDLV   DWTSRV+HLLNDQH+GVVTAA SLI +L +++PEE+K  VSLAVSRLSRIVTS+ TDLQDYTYYFVPAPWLSVKLLRLLQ YPPPD A VR RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA +IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP IQF +LH+K+HLC+  TR LLLSTY+KF+NLFPE+K  IQD+L++DS LRNADVE+QQR +EYL LS +A+ D++ATVLEEMP F ERESSIL                        AK+  K    T  D   TK +   + VD+ GG      P  T++ ST  P++DLL         +                +++ S   P+      S++N+ + + K++G+LFEN  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F  T +C+      L L   P+   +  G Q QQ +NIEC   F +   L + F        + + LPIT+NKF +   M    FFQRWK L  P QE Q++ K+ K PM+  V + ++ G   ++L  +DP  +NFV +GI++  + ++G LLRLEPN+  ++YRLT+R++K+ VS+++  ++ +
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPA-VRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEDTKRD---RSVDVNGG--PEPAPASTSAVSTPSPSADLLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLA---PGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEGGAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKA-KHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSA 937

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BLAST of AP-2 complex subunit alpha vs. TrEMBL
Match: A0A1S8WI37 (AP-2 complex subunit alpha OS=Opisthorchis viverrini OX=6198 GN=X801_10093 PE=3 SV=1)

HSP 1 Score: 1332.01 bits (3446), Expect = 0.000e+0
Identity = 663/982 (67.52%), Postives = 785/982 (79.94%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATK---------EEPAIQEVDLLG-GLFSYSQP--NQTNSKST----SQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI-------------LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIE 2887
            MP+ KG++MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGH+EAVNLLCSN+YTEKQIGYLFISVLINE+H LMNLV+ RLKDDLSSRNPVFV LALQCIANIG+REM ENFA+EIP+LLVSGDTIDS+KQ+AALC+L+LIR AP+L+ +DDWT R IHLLNDQH+GVVT+AVSLI++LVKRSPEE+K CV LAVSRLSR++TSSYTDLQDYTYYFV APWLSVKLLRLLQNYPPP+D  VR+RLTECLE+IL K QEPPKSKKVQH NAKNAVLFEAINLIIHMDCD  LL+RACNQLGQFL H+ETNLRYLALES+CLLATSEFSHEAVKKHQET++SALKSERDVSVRQRAVDLLYA+CDR NA+ IVGEMLSYLE ADYSIREEMVLKVAIL+EKYATDYSWYVDTILNLIRVAGDYVS+EVWHRVIQIV+NR D+QGY+AKTVFEALQAPACHENMVKVG Y+LGEFGNLIAGD RSSP+IQF +LH+K+HLCTP TRQL+LSTY+KFINLFPEIK +IQD+L NDSNLR+++VEIQQR  EYL LS+IATDDV+ATVLEEMP F ERESSILAKLK                ++P +++  N  +T   + AT           +P  +E DLLG G  S SQP  NQ + K+T    S P + LL+DILG+   ++ +    ST    L + E    ++ LL + SG+LFEN  IQIG++S+   ++ RL +FYGN S   +T+F  +L +    T              L + L P    +  G Q QQ +NIEC Q F    SL V F   +  Y  +L LPIT+ KF++ A MDQN +F RWK+L QPGQECQS+ ++ + PM+ +V++ +L G  +SVL  +DP   NFV +GI+ MS+Q+VG+L RLEPN   K+YRLTVRST+D+V++++  ++E
Sbjct:    1 MPSAKGETMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHTEAVNLLCSNRYTEKQIGYLFISVLINEAHPLMNLVITRLKDDLSSRNPVFVNLALQCIANIGSREMAENFAQEIPKLLVSGDTIDSIKQNAALCMLRLIRIAPELITYDDWTVRTIHLLNDQHLGVVTSAVSLIDALVKRSPEEHKGCVPLAVSRLSRLITSSYTDLQDYTYYFVTAPWLSVKLLRLLQNYPPPEDTSVRARLTECLETILRKVQEPPKSKKVQHPNAKNAVLFEAINLIIHMDCDSKLLVRACNQLGQFLQHKETNLRYLALESLCLLATSEFSHEAVKKHQETIVSALKSERDVSVRQRAVDLLYAVCDRTNAQAIVGEMLSYLEVADYSIREEMVLKVAILAEKYATDYSWYVDTILNLIRVAGDYVSDEVWHRVIQIVVNREDIQGYAAKTVFEALQAPACHENMVKVGAYVLGEFGNLIAGDERSSPKIQFHLLHSKFHLCTPNTRQLMLSTYMKFINLFPEIKADIQDVLMNDSNLRSSNVEIQQRATEYLALSRIATDDVLATVLEEMPPFPERESSILAKLKA---------------KNPNSEVPMNKSETPAPTDATTPSTPRLAQLAKPG-EEADLLGLGFLSSSQPSQNQESEKATTLSGSTPGNRLLVDILGSEHPTNGSFMDEST---ILNKGE----FISLLSRPSGVLFENRVIQIGLRSQSNRHLCRLTLFYGNNSSHPLTNFNVQLSSESAETTGQQMDALNGLSAPLSIQLLPGPDMVELGAQVQQVINIECHQPFTHHTSLVVSFVSGEWKYHYVLLLPITLGKFIQPAEMDQNLYFTRWKLLSQPGQECQSIFRA-QFPMDSNVVKKKLLGFGISVLQGVDPNPQNFVGAGILTMSNQEVGILTRLEPNFQAKMYRLTVRSTRDVVAKRVGQLLE 958

[Close]

BLAST of AP-2 complex subunit alpha vs. TrEMBL
Match: A0A4S2L4V5 (AP-2 complex subunit alpha OS=Opisthorchis felineus OX=147828 GN=CRM22_009954 PE=3 SV=1)

HSP 1 Score: 1328.92 bits (3438), Expect = 0.000e+0
Identity = 660/976 (67.62%), Postives = 781/976 (80.02%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXX---XXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKE--EPAIQEVDLLG-GLFSYSQP--NQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSE--SDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPP-------------TTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIE 2887
            MP+ K ++MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGH+EAVNLLCSN+YTEKQIGYLFISVLINE+H LMNLV+ RLKDDLSSRNPVFV LALQCIANIG+REM ENFA+EIP+LLVSGDTIDS+KQ+AALC+L+LIR AP+L+ +DDWT R IHLLNDQH+GVVT+AVSLI++LVKRSPEE+K CV LAVSRLSR++TSSYTDLQDYTYYFV APWLSVKLLRLLQNYPPP+D  VR+RLTECLE+IL K QEPPKSKKVQH NAKNAVLFEAINLIIHMDCD  LL+RACNQLGQFL H+ETNLRYLALES+CLLATSEFSHEAVKKHQET++SALKSERDVSVRQRAVDLLYA+CDR NA+ IVGEMLSYLE ADYSIREEMVLKVAIL+EKYATDYSWYVDTILNLIRVAGDYVS+EVWHRVIQIV+NR D+QGY+AKTVFEALQAPACHENMVKVG Y+LGEFGNLIAGD RSSP+IQF +LH+K+HLCTP TRQL+LSTY+KFINLFPEIK +IQD+L NDSNLR+++VEIQQR  EYL LS+IATDDV+ATVLEEMP F ERESSILAKLK K       +   E  AP    T    + +   + D+ AT +  +P   EVDLLG G  S SQP  NQ   K+T+ P S       GNG   DI  ++  TN   +++S   +   ++ LL + SG+LFEN  IQIG++S+   ++ RL +FYGN S   +T F  +L +                +  L + L P    +  G Q QQ +NIEC Q F    SL V F      ++ +L LPIT+ KF++ A MDQN +F RWK+L QPGQECQS+ ++ +  M+ +V++ +L G  +SVL  +DP   NFV +GI+ +S+Q+VG+L RLEPN   K+YRLTVRST+D+V++++  ++E
Sbjct:    1 MPSAKSETMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHTEAVNLLCSNRYTEKQIGYLFISVLINEAHPLMNLVITRLKDDLSSRNPVFVNLALQCIANIGSREMAENFAQEIPKLLVSGDTIDSIKQNAALCMLRLIRIAPELITYDDWTVRTIHLLNDQHLGVVTSAVSLIDALVKRSPEEHKGCVPLAVSRLSRLITSSYTDLQDYTYYFVTAPWLSVKLLRLLQNYPPPEDTSVRARLTECLETILRKVQEPPKSKKVQHPNAKNAVLFEAINLIIHMDCDSKLLVRACNQLGQFLQHKETNLRYLALESLCLLATSEFSHEAVKKHQETIVSALKSERDVSVRQRAVDLLYAVCDRTNAQAIVGEMLSYLEVADYSIREEMVLKVAILAEKYATDYSWYVDTILNLIRVAGDYVSDEVWHRVIQIVVNREDIQGYAAKTVFEALQAPACHENMVKVGAYVLGEFGNLIAGDERSSPKIQFHLLHSKFHLCTPNTRQLMLSTYMKFINLFPEIKADIQDVLMNDSNLRSSNVEIQQRATEYLALSRIATDDVLATVLEEMPPFPERESSILAKLKAKNPNSEVPMNKSETPAPTDATTPSTPRLAQLAKGDNAATNQTSQPG-GEVDLLGLGFLSSSQPSQNQDFQKTTTLPAS-----TPGNGLLVDILGSEHPTNGSFMDESTILNKREFVSLLSRPSGVLFENSVIQIGLRSQSNRHLCRLTLFYGNNSSHPLTSFNVQLSSESAEATGQQTDALNGLSAPLSIQLLPGPDMVELGAQVQQVINIECHQPFTHHTSLVVSFVCGDSKHRYVLLLPITLGKFIQPAEMDQNLYFTRWKLLSQPGQECQSIFRA-QFSMDSNVIKKKLLGFGISVLQGVDPNPQNFVGAGILTLSNQEVGILTRLEPNFQAKMYRLTVRSTRDVVAKRVGQLLE 969

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BLAST of AP-2 complex subunit alpha vs. TrEMBL
Match: A0A4S2LAF5 (AP-2 complex subunit alpha OS=Opisthorchis felineus OX=147828 GN=CRM22_009954 PE=3 SV=1)

HSP 1 Score: 1313.13 bits (3397), Expect = 0.000e+0
Identity = 660/1003 (65.80%), Postives = 781/1003 (77.87%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVM---------------------------ATVLEEMPSFTERESSIXXXXXXX---XXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKE--EPAIQEVDLLG-GLFSYSQP--NQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSE--SDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPP-------------TTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIE 2887
            MP+ K ++MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGH+EAVNLLCSN+YTEKQIGYLFISVLINE+H LMNLV+ RLKDDLSSRNPVFV LALQCIANIG+REM ENFA+EIP+LLVSGDTIDS+KQ+AALC+L+LIR AP+L+ +DDWT R IHLLNDQH+GVVT+AVSLI++LVKRSPEE+K CV LAVSRLSR++TSSYTDLQDYTYYFV APWLSVKLLRLLQNYPPP+D  VR+RLTECLE+IL K QEPPKSKKVQH NAKNAVLFEAINLIIHMDCD  LL+RACNQLGQFL H+ETNLRYLALES+CLLATSEFSHEAVKKHQET++SALKSERDVSVRQRAVDLLYA+CDR NA+ IVGEMLSYLE ADYSIREEMVLKVAIL+EKYATDYSWYVDTILNLIRVAGDYVS+EVWHRVIQIV+NR D+QGY+AKTVFEALQAPACHENMVKVG Y+LGEFGNLIAGD RSSP+IQF +LH+K+HLCTP TRQL+LSTY+KFINLFPEIK +IQD+L NDSNLR+++VEIQQR  EYL LS+IATDDV+                           ATVLEEMP F ERESSILAKLK K       +   E  AP    T    + +   + D+ AT +  +P   EVDLLG G  S SQP  NQ   K+T+ P S       GNG   DI  ++  TN   +++S   +   ++ LL + SG+LFEN  IQIG++S+   ++ RL +FYGN S   +T F  +L +                +  L + L P    +  G Q QQ +NIEC Q F    SL V F      ++ +L LPIT+ KF++ A MDQN +F RWK+L QPGQECQS+ ++ +  M+ +V++ +L G  +SVL  +DP   NFV +GI+ +S+Q+VG+L RLEPN   K+YRLTVRST+D+V++++  ++E
Sbjct:    1 MPSAKSETMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHTEAVNLLCSNRYTEKQIGYLFISVLINEAHPLMNLVITRLKDDLSSRNPVFVNLALQCIANIGSREMAENFAQEIPKLLVSGDTIDSIKQNAALCMLRLIRIAPELITYDDWTVRTIHLLNDQHLGVVTSAVSLIDALVKRSPEEHKGCVPLAVSRLSRLITSSYTDLQDYTYYFVTAPWLSVKLLRLLQNYPPPEDTSVRARLTECLETILRKVQEPPKSKKVQHPNAKNAVLFEAINLIIHMDCDSKLLVRACNQLGQFLQHKETNLRYLALESLCLLATSEFSHEAVKKHQETIVSALKSERDVSVRQRAVDLLYAVCDRTNAQAIVGEMLSYLEVADYSIREEMVLKVAILAEKYATDYSWYVDTILNLIRVAGDYVSDEVWHRVIQIVVNREDIQGYAAKTVFEALQAPACHENMVKVGAYVLGEFGNLIAGDERSSPKIQFHLLHSKFHLCTPNTRQLMLSTYMKFINLFPEIKADIQDVLMNDSNLRSSNVEIQQRATEYLALSRIATDDVLLIRPNDNGEVPPQPLLPTGRTFLSCPQATVLEEMPPFPERESSILAKLKAKNPNSEVPMNKSETPAPTDATTPSTPRLAQLAKGDNAATNQTSQPG-GEVDLLGLGFLSSSQPSQNQDFQKTTTLPAS-----TPGNGLLVDILGSEHPTNGSFMDESTILNKREFVSLLSRPSGVLFENSVIQIGLRSQSNRHLCRLTLFYGNNSSHPLTSFNVQLSSESAEATGQQTDALNGLSAPLSIQLLPGPDMVELGAQVQQVINIECHQPFTHHTSLVVSFVCGDSKHRYVLLLPITLGKFIQPAEMDQNLYFTRWKLLSQPGQECQSIFRA-QFSMDSNVIKKKLLGFGISVLQGVDPNPQNFVGAGILTLSNQEVGILTRLEPNFQAKMYRLTVRSTRDVVAKRVGQLLE 996

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BLAST of AP-2 complex subunit alpha vs. TrEMBL
Match: A0A4Z2CS53 (AP-2 complex subunit alpha OS=Schistosoma japonicum OX=6182 GN=EWB00_007966 PE=3 SV=1)

HSP 1 Score: 1308.51 bits (3385), Expect = 0.000e+0
Identity = 650/962 (67.57%), Postives = 768/962 (79.83%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDS-DINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI------LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIE--KQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIE 2887
            MP+ KGD+MRGLAVFISDIRNCKSKE+EI+R+N+ELANIRSKF+GDKTLDGYQKKKYVCKLLFIFLLGH+IDFGH+EAVNLLCSN+YTEKQIGYLFISVLINESH LMNLV+ RLKDDL+SRNPVF+ LALQCIANIG+REM ENFA +IP+LLVSGDTIDS+KQ+AALCLLKLIR AP+LV +DDWT R +HLLNDQH+GVVT+AVSLI++LVKRSPEE+K C+SLAVSRLSR++TSSYTDLQDYTYYFV APWLSVKLLRLLQNYPPP+D  VR+RL ECL++IL K QE PKSKKVQH NAKNAVLFEAINLIIHMDCDP LL+RACNQLGQFL H+ETNLRYLALES+CLLATSEFSHEAVKKHQET+++ALKSERDVSVRQRAVDLLYAMCDR NA+ IVGEMLSYLE ADY+IREEMVLKVAIL+EKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRS+P++QF +LH+K+HLCTPTTRQLLLSTY+KFINLFPEIK +IQ +L+NDSNLR+++VEIQQR  EYL LS+IATDDV+ATVLEEMP F ER SSI     + K    +G    +     +  +S + ++  N     +      E DLL    S +  N   SK      S LL+DI+GNG  S DIN    ++     +Q  + + +   L + + IL+EN  I+IGI+ E RG   RLG+FYGNKS    T F +++       +      + ++L P    I +G Q QQ LN+EC + F + + L V +  E  KQ Y +M  LPIT+NKF++ A MDQ TFF RWK+L QPGQECQ +  +L  P+E + ++T  +    S+L  IDP   N V +GIV  SSQ++GVLLRLEPN  +K+YRLT+RST+DIVS  +  ++E
Sbjct:    1 MPSTKGDAMRGLAVFISDIRNCKSKESEIRRVNKELANIRSKFRGDKTLDGYQKKKYVCKLLFIFLLGHEIDFGHTEAVNLLCSNRYTEKQIGYLFISVLINESHPLMNLVISRLKDDLNSRNPVFMNLALQCIANIGSREMAENFADKIPKLLVSGDTIDSIKQNAALCLLKLIRVAPELVTYDDWTVRAMHLLNDQHLGVVTSAVSLIDALVKRSPEEHKGCISLAVSRLSRLITSSYTDLQDYTYYFVTAPWLSVKLLRLLQNYPPPEDTTVRARLAECLDTILKKVQEAPKSKKVQHPNAKNAVLFEAINLIIHMDCDPKLLVRACNQLGQFLQHKETNLRYLALESLCLLATSEFSHEAVKKHQETIVNALKSERDVSVRQRAVDLLYAMCDRTNAQAIVGEMLSYLEVADYAIREEMVLKVAILAEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINREDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSAPKVQFNLLHSKFHLCTPTTRQLLLSTYMKFINLFPEIKSDIQSVLQNDSNLRSSNVEIQQRATEYLALSRIATDDVLATVLEEMPPFPERHSSI-LAKLKAKNPNTDGATPKSDAVGESYGLSSSKVNHDNSHNLNR------EADLLNFGNSGTVYNDVQSKPNG---SCLLVDIIGNGVTSTDINNLLHTSGG---DQYMNRKEFTNFLTRHNAILYENSLIRIGIRMESRGQFCRLGVFYGNKSPHPFTVFCSQVTCPDAMDVNEIAKAISIELQPGPDRIEAGTQVQQSLNVECLRPFTEVVKLDVSYLCEDSKQHYALM--LPITLNKFLQPAEMDQATFFSRWKLLSQPGQECQKIHPAL-FPLETTTMRTTTKNFGFSLLDGIDPNPQNIVGAGIVVTSSQQIGVLLRLEPNSQSKMYRLTIRSTRDIVSSHLVKLME 946

[Close]

BLAST of AP-2 complex subunit alpha vs. TrEMBL
Match: A0A4E0RYB5 (AP-2 complex subunit alpha OS=Fasciola hepatica OX=6192 GN=D915_007766 PE=3 SV=1)

HSP 1 Score: 1303.5 bits (3372), Expect = 0.000e+0
Identity = 642/967 (66.39%), Postives = 776/967 (80.25%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSG-DTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAI-QEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILG-NGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTEL-CNSPPTTI--------LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNI--EKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIE 2887
            MP+ K ++MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGH+EAVNLLCSN+YTEKQIGYLFISVLINE+H LMNLV+ RLKDDLSSRNPVFV LALQCIANIG+REM ENF +E+P+LLVSG DTIDS+KQ+AALC+L+LIR AP+L+ +DDWT R IHLLNDQH+GVVT+AVSLI++LVKR+PEE+K CVSLAVSRLSR++TSSYTDLQDYTYYFV APWLSVKLLRLLQNYPPP+D  VR+RLTECL++IL K QEPPKSKKVQHSNAKNAVLFEAINLIIHMDCD  LL+RACNQLGQFL H+ETNLRYLALES+CLLATSEFSHEAVKKHQET+++ALKSERDVSVRQRAV+LLYAMCDR NA+ IVGEMLSYLE ADYSIREEMVLKVAIL+EKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIV+NR DVQGY+AKTVFEALQAPACHENMVKVG YILGEFGNLIAGDPRS+P +QF +LH+K+HLCT TTRQL+LSTY+KFINLFPEIK +IQD+L+NDSNLR++D+EIQQR  EYL LS+ A+DD +A VLEEMP F ERESSI   L + K      + +   +  P  ++ +     +ND   +    A+  EVDLL GL S S       K       +LL+DILG NG   +   + +  +      + + + ++ LL ++SGILFE+  IQIG +S+   ++ RL +FYGNKS   +T+F T++ C   P TI        L ++L P  + +    Q QQ +N+ECF  F ++  L +  N    +Q Y I+  LPITI +F++ A M+QN FF RWK+L QPGQE Q +  + + PM+ +V++ +L G  +SVL  IDP   N V +GI+ +S+Q++G+LLRLEPN   ++YRLTVRST+DIV++++ +++E
Sbjct:    1 MPSSKSEAMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHTEAVNLLCSNRYTEKQIGYLFISVLINEAHPLMNLVITRLKDDLSSRNPVFVNLALQCIANIGSREMAENFVQEVPKLLVSGSDTIDSIKQNAALCMLRLIRIAPELITYDDWTVRTIHLLNDQHLGVVTSAVSLIDALVKRNPEEHKGCVSLAVSRLSRLITSSYTDLQDYTYYFVTAPWLSVKLLRLLQNYPPPEDPTVRARLTECLDTILKKVQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDSKLLVRACNQLGQFLQHKETNLRYLALESLCLLATSEFSHEAVKKHQETIVNALKSERDVSVRQRAVNLLYAMCDRTNAQAIVGEMLSYLEVADYSIREEMVLKVAILAEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVVNREDVQGYAAKTVFEALQAPACHENMVKVGAYILGEFGNLIAGDPRSAPSVQFDLLHSKFHLCTSTTRQLMLSTYIKFINLFPEIKPQIQDVLQNDSNLRSSDIEIQQRAAEYLALSRTASDDFLAKVLEEMPPFPERESSI---LVKLKARNPNSEHVTTTKMEPNVRV-EGVQSIKNDIAKSNANAALGSEVDLL-GLGSLSPVAPVQQKVAQSAGDNLLVDILGTNGTTENGTMSSALMHADLSAAAMNKKEFISLLSRTSGILFEDRVIQIGFRSQSNRHLSRLTLFYGNKSPHPLTEFRTQVHC---PETIDLTGHGRALSIELQPGPNTVELDAQIQQVVNVECFHPFTESAVLSLSLNCGGSQQQYTIL--LPITIGRFIQPAEMEQNLFFTRWKLLSQPGQESQKIFHA-QFPMDPNVVRNKLLGFGISVLQGIDPNPQNLVGAGILTVSTQEIGILLRLEPNTQAQMYRLTVRSTRDIVAKRVCDLLE 956

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Cavefish
Match: ap2a1 (adaptor related protein complex 2 subunit alpha 1 [Source:ZFIN;Acc:ZDB-GENE-090302-2])

HSP 1 Score: 1224.15 bits (3166), Expect = 0.000e+0
Identity = 612/954 (64.15%), Postives = 726/954 (76.10%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTS-DLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L + +PDLV   +WTSRV+HLLNDQHMGVVTAA+SLI  L +++P+E+K CVSLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLS KLLRLLQ YPPP+D  V+ RL ECLE+IL+KAQEPPKSKKVQHSNAKNA+LFEAI LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EMLSYLE+ADYSIREEMVLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLS Y+KFINLFPE K  IQ++L+ DS +RN+DVE+QQR +EYL LS IA+ DV+ATVLEEMP F ERESSILAKLK+KK       EL         K     L+   + P           DLLG     + P      S + P++  LL+D+             S   P     S +D+ +L+ + K++G+LFEN  +QIGIKSE+R N+GR+ +FYGNK+  Q   F         TT L + L P+   +  G Q QQ +NIEC   F +   L + F        + L LP+TINKF +   M  N FFQRWK L QP QE Q + K+    M+  V++ +L GL  ++L  +DP   NFV +G++   SQ+VG LLRLEPN   ++YRLT+RS+KD VS+++ +++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMCLALHCIANVGSREMAEAFAGEIPRILVAGDTMDSVKQSAALCLLRLYKTSPDLVLMGEWTSRVVHLLNDQHMGVVTAAISLITCLSQKNPDEFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSCKLLRLLQCYPPPEDGAVKGRLVECLETILNKAQEPPKSKKVQHSNAKNAILFEAIALIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVAEMLSYLETADYSIREEMVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPLVQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPETKTTIQEVLRCDSQIRNSDVELQQRAVEYLKLSSIASTDVLATVLEEMPPFPERESSILAKLKKKKGPGAVSNEL------EEGKREGGELNGAGERPGDSSSTPSPSADLLG--LRSAAP-----VSAAPPSAGSLLVDVF------------SEAGPAAPAASVNDDGFLRFVCKNNGVLFENQLLQIGIKSEYRQNLGRMYLFYGNKTSVQFVSF---------TTTLNVQLKPVDPLVEGGAQVQQVINIECITDFSEAPILNIKFRYGGALQNLSLKLPVTINKFFQPTEMASNDFFQRWKQLSQPQQEAQKIFKA-NHAMDTEVIKAKLLGLGTALLDKVDPNPENFVCAGVIQTKSQQVGCLLRLEPNAQAQMYRLTLRSSKDTVSKRLCDLL 919

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BLAST of AP-2 complex subunit alpha vs. Ensembl Cavefish
Match: ENSAMXT00000003083.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:1159885:1191476:1 gene:ENSAMXG00000002953.2 transcript:ENSAMXT00000003083.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 1177.93 bits (3046), Expect = 0.000e+0
Identity = 588/938 (62.69%), Postives = 711/938 (75.80%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSES----DENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTE-LCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKI 2824
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N + +L+ L+   +K+DLSSRNP ++ LAL CIAN+G+REM E FA E+PR+LV+GDT+DSVKQSAALCLL+L R +PDLV   +WTSRV+HLLNDQH+GVVTAA SLI +L +++P+++K  VSLAV+RLSRIVTS+ TDLQDYTYYFV APWLSVKLLRLLQ YPPP++  +R RLTECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAI+LIIH D +P LL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI++LK+ERDVSVRQRAVDLLYAMCDR+NA++IV EMLSYLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLS YVKFINLFPE+K  IQ++L++DS LRNADVE+QQR +EYL LS IAT D++ATVLEEMP F ERESSI       K    +G   ++  +    + + N+      SP++         DLLG     S    + S  TS   + LL+D+             S + P+    S S    +EN+ + + K++G+LFE+  +QIG+KSEFR N+GR+ IFYGNK+  Q  +F +  +C  P T    LD          G Q QQ LNIEC   F +   L + F     +  I + LP+T+NKF +   M    FFQRWK L  P QE Q + K+ K  M+  + + ++ G   ++L  +DP  SNFV +G+++  + +VG LLRLEPN   ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSDLIRLINNAIKNDLSSRNPTYMNLALHCIANVGSREMAEAFASEVPRILVAGDTMDSVKQSAALCLLRLNRTSPDLVPMGEWTSRVVHLLNDQHLGVVTAATSLISTLAQKNPDDFKTSVSLAVARLSRIVTSASTDLQDYTYYFVAAPWLSVKLLRLLQCYPPPEEGAIRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPTLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINSLKTERDVSVRQRAVDLLYAMCDRSNAKQIVTEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLVQFHLLHSKFHLCSVPTRALLLSAYVKFINLFPEVKGTIQEVLRSDSQLRNADVELQQRAVEYLRLSCIATTDILATVLEEMPPFPERESSI-----LAKLKKKKGSGTVSDIEDSRKERNVNANANVTSSPSS---------DLLG--LGNSSAVNSASPPTSSHAASLLVDVF------------SESLPVAALGSASAHVIEENFSRFVCKNNGVLFESQLLQIGLKSEFRQNLGRMYIFYGNKTSTQFLNFSSSVVCPEPLTADPVLD---------GGAQLQQILNIECISDFVEAPVLNIQFRYGGSTQNISVRLPVTLNKFFQPTEMTSQDFFQRWKQLSPPQQEVQKIFKA-KHSMDTEITKAKIIGFGTALLDGVDPNPSNFVGAGVIHTKTIQVGCLLRLEPNTQAQV 900

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Cavefish
Match: ap1g1 (adaptor related protein complex 1 subunit gamma 1 [Source:NCBI gene;Acc:103024714])

HSP 1 Score: 264.233 bits (674), Expect = 4.369e-75
Identity = 177/600 (29.50%), Postives = 324/600 (54.00%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPQIQ------FQILHAKY--HLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMP 1834
             I  IR  +++  E + I +E A IRS F+ +   D   + + V KLL++ +LG+   FG  E + L+ S K+T+K+IGYL   +L++E  ++  L+   +K+DL+        LAL  +  +G+ EM  + A E+ +LL + ++   +++ AALC + +IR  P+L+    +     +LL++++ GV+  +V L+  + +RSP+    ++  V   V  L  ++ S Y+   D +   +  P+L V++LRLL+     DD       +E +  IL++     ++ K    N  NA+L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL S  LL T +  H AV++H+ T++  LK + DVS+++RA++L +A+ + NN   ++ E+L +L+S D   + +    V + +EKYA    W++DTI+ ++  AG YV ++    +IQ++ N  ++  Y+ + +++AL      + +V+V  + +GE+G+ L++G       IQ        +L      +L  P TR   L+  +K    F  +    + +    S++   DVE+QQR +EY  L K   D +   +LE MP
Sbjct:   10 LIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPATKNLLSEKNHGVLHTSVVLLTEMCERSPDMLTHFRKLVPQLVRILKNLIMSGYSPEHDVS--GISDPFLQVRILRLLRILGKSDDDS-----SEAMNDILAQVATNTETSK----NVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTS--LLKTVQTDHNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCDPDFKADCASGVFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDSVPNLIQLITNSVEMHAYTVQRLYKALLDDISQQPLVQVASWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDVLEGLLVSNLSAPVTRGYSLTAIMKLSTRFSSVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRPALLERMP 584

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Cavefish
Match: ap1g1 (adaptor related protein complex 1 subunit gamma 1 [Source:NCBI gene;Acc:103024714])

HSP 1 Score: 263.848 bits (673), Expect = 9.394e-75
Identity = 177/600 (29.50%), Postives = 324/600 (54.00%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPQIQ------FQILHAKY--HLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMP 1834
             I  IR  +++  E + I +E A IRS F+ +   D   + + V KLL++ +LG+   FG  E + L+ S K+T+K+IGYL   +L++E  ++  L+   +K+DL+        LAL  +  +G+ EM  + A E+ +LL + ++   +++ AALC + +IR  P+L+    +     +LL++++ GV+  +V L+  + +RSP+    ++  V   V  L  ++ S Y+   D +   +  P+L V++LRLL+     DD       +E +  IL++     ++ K    N  NA+L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL S  LL T +  H AV++H+ T++  LK + DVS+++RA++L +A+ + NN   ++ E+L +L+S D   + +    V + +EKYA    W++DTI+ ++  AG YV ++    +IQ++ N  ++  Y+ + +++AL      + +V+V  + +GE+G+ L++G       IQ        +L      +L  P TR   L+  +K    F  +    + +    S++   DVE+QQR +EY  L K   D +   +LE MP
Sbjct:   10 LIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPATKNLLSEKNHGVLHTSVVLLTEMCERSPDMLTHFRKLVPQLVRILKNLIMSGYSPEHDVS--GISDPFLQVRILRLLRILGKSDDDS-----SEAMNDILAQVATNTETSK----NVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTS--LLKTVQTDHNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCDPDFKADCASGVFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDSVPNLIQLITNSVEMHAYTVQRLYKALLDDISQQPLVQVASWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDVLEGLLVSNLSAPVTRGYSLTAIMKLSTRFSSVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRPALLERMP 584

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Cavefish
Match: ap1g2 (AP-1 complex subunit gamma-1 [Source:NCBI gene;Acc:103044685])

HSP 1 Score: 259.225 bits (661), Expect = 2.256e-73
Identity = 181/608 (29.77%), Postives = 328/608 (53.95%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPQIQF---QILHA-----KYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESS 1858
             I  IR  +++  E   I RE A IR++F+     D   +   + KLL++ +LG+   FG  E V L+ S+KY+EK+IGYL   +L++E  +   L+   +K+DLS  +    +LAL  +A +G+ EM  + A EI RLL + ++   +K+ AALC + ++R  P+L     +T     LL++++ GV+  AV LI  L +R+P+   +++  V   V  +  +VTS Y+   ++    +  P+L V++LRLL+     +DA      ++ +  +L++      S K     A +AVL+E +  I+ +  +  L + A N LG+FL + + N+RY+++ S+  +  ++  H AV++H+ T++  LK ++D SV++RA++L  A+    N   ++ E+L +L +    +R      +   +E+YA    W++DTIL+++  AG  V +E    +IQ++   S++  Y+   ++ AL +    +++V+V  + +GE+G+ L+ G+      +Q     +L A     + H+ TPT+R   L+  +K         + I+ ++    +    DVE+QQR +EY  L K   D + A VLE MP   +R SS
Sbjct:   10 MIRVIRGARTQGEERGVIQRECAAIRAQFR---QADNGGRSHNLAKLLYVHMLGYPAHFGQMECVRLIASSKYSEKRIGYLGAMMLLDEKQDASLLITNSIKNDLSHSSQHVQSLALCTLACMGSAEMCRDLAPEIERLLKASNSY--IKKKAALCAVHIVRKIPELGEM--FTPSAHSLLSEKNHGVLHGAVILITELCERNPDNLKQFRKSVPELVQIMKNLVTSGYSP--EHNVAGISDPFLQVRILRLLRILGRNNDAA-----SDAMNDLLAQVATNTDSSKT----AGSAVLYETVLTIMDIRSESGLRVLAVNILGRFLLNNDRNIRYISMTSLQKIVQTD--HTAVQRHRGTIVDCLK-DQDASVKRRALELSLALVSAANIRSMMKELLLFLSTCPPELRSHAASGIFNAAERYAPSQRWHIDTILHVLVTAGGDVRDETVPNLIQLITAASELHCYTVHKLYRALISDIVQQSLVQVACWCIGEYGDLLLKGECEEITPMQVTEDDVLDALETVLQSHMSTPTSRGFALTAIMKLSTRITNNVDRIRSVVSIYGSC--IDVELQQRAVEYNALFK-KYDHMRAAVLERMP-VIDRNSS 592

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BLAST of AP-2 complex subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002119.1 (pep scaffold:Pmarinus_7.0:GL476740:177496:198372:1 gene:ENSPMAG00000001871.1 transcript:ENSPMAT00000002119.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 1160.59 bits (3001), Expect = 0.000e+0
Identity = 581/962 (60.40%), Postives = 713/962 (74.12%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFK-GDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLN--------PIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFK GDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   LK+DL SRNPV + LAL CIAN+G+REM E  A EIP+LL+S DT+  VKQSAALCLL+LIR +P+LV   DW SRVIHLLNDQHMGV TAA SLI +L ++SP+EY+  VSLAVSRLSR+VT++YTDLQDYTYY+V APWLSVKLLRLLQ +P P++  VR RL ECLESIL+KAQEPPKSKKVQHSNAKNAVLFEAINLIIH D +PNLL+RACNQLGQFL HRETNLRYLALE +CLLA+SEFSHEAVKKHQETVI+ALK+ERDVSVRQRAVDLLY MCDR NA+++V EML YLE+ADYSIREEMVLKVAIL+EKYA DY+WYVDT+LNLIRVAGDYVSEEVW+RVI IV+N  +VQGY+AKTVFEALQAP+CHENMVKVGGY+LGEFGNLIAGDPRSSP +QF +LH+K+HLC+ +TR LLLSTYVKFINLFPEI+  +Q +L++D+ L NAD E+QQR +EYLTLS +A+ DV+ATVLEEMP F ERESSI       K     G  +  P     AK    S       P     P++  V +  G       +   +         LL+DI      +D   +++   P      + +EN+L+ + K++G+L+EN  +QIG+KSE++ N+G++ +FYGNK+  Q  +F        PT     DL          ++  + +G Q QQ L +EC   F +   L +         +I L LPI INKF +   M+   FF RWK L  P QE Q + K+    M+  V + +L G  +++L  +DP   N+V++GI++  S ++G LLRLEPNM +++YRLT+RS+K+ VS+++ +++
Sbjct:   12 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKAGDKPLDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNALKNDLMSRNPVSICLALHCIANVGSREMAEALAAEIPKLLISADTMHGVKQSAALCLLRLIRGSPELVPQGDWASRVIHLLNDQHMGVATAAASLITALAQKSPDEYRGSVSLAVSRLSRVVTAAYTDLQDYTYYYVQAPWLSVKLLRLLQCFPLPEETTVRGRLNECLESILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHQDSEPNLLVRACNQLGQFLQHRETNLRYLALEGLCLLASSEFSHEAVKKHQETVITALKTERDVSVRQRAVDLLYGMCDRTNAQQVVSEMLGYLETADYSIREEMVLKVAILAEKYAVDYTWYVDTVLNLIRVAGDYVSEEVWYRVIHIVVNNDEVQGYAAKTVFEALQAPSCHENMVKVGGYVLGEFGNLIAGDPRSSPIVQFNLLHSKFHLCSASTRALLLSTYVKFINLFPEIRSSVQQVLRSDNQLCNADAELQQRAVEYLTLSNVASTDVLATVLEEMPPFPERESSI-----LTKLRKKRGTSITEPDD---AKKPSGSEVNGGSEPM----PSVGAVHVPVGSGPGLAGHSGAATGGGSGGGSLLVDIF-----ADAAGSQAGAVP------DIEENFLRFVCKNNGVLYENSFLQIGVKSEYQQNVGQVCLFYGNKTSSQFQNF-------TPTIAYPGDLQANILFQSKAVQPQVDAGAQVQQLLRVECLGDFTEAPGLTLQLWHGGSLQQISLKLPIMINKFFQPTEMNSQDFFVRWKQLSSPQQEAQKIFKAAHS-MDTEVCKAKLLGSGMALLEGVDPNPGNYVSAGIIHTKSLQIGCLLRLEPNMQSEMYRLTIRSSKESVSQRLCDLL 942

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BLAST of AP-2 complex subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000025.1 (pep scaffold:Pmarinus_7.0:GL482217:474:17538:-1 gene:ENSPMAG00000000021.1 transcript:ENSPMAT00000000025.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 881.322 bits (2276), Expect = 0.000e+0
Identity = 415/516 (80.43%), Postives = 463/516 (89.73%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRS 1576
            +P++     RG    I+D    KSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +++DLSSRNP+F+ LAL CIAN+G+REM E  A E+P+LL++ DT+DSVKQSAALCLL+L R +PD++   DWTSRVIHLLNDQHMGVVTAA SLI +L +++PEEYK  VSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQ YPPP+D  VR RL+ECLE+IL+KAQEPPKSKKVQHSNAKNAVLFEAINLIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMCLLA+SEFSHEAVKKHQETVI+ALK+ERDVSVRQRAVDLLYAMCDR+NA+EI  EML+YLE+ADYSIREEMVLKVAIL+E+YA DY+WYVDTILNLIR+AGDYVSEEVW+RVIQIV NR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRS
Sbjct:    1 VPSLLEVQARGTRTIIADCARRKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLISNAIRNDLSSRNPIFINLALHCIANVGSREMAEALASEVPKLLIASDTMDSVKQSAALCLLRLYRTSPDVIPVGDWTSRVIHLLNDQHMGVVTAATSLITALAQKNPEEYKGSVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLSECLENILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCLLASSEFSHEAVKKHQETVINALKTERDVSVRQRAVDLLYAMCDRSNAQEITSEMLNYLETADYSIREEMVLKVAILAERYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRS 516

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BLAST of AP-2 complex subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003410.1 (pep scaffold:Pmarinus_7.0:GL480964:25073:33111:1 gene:ENSPMAG00000003123.1 transcript:ENSPMAT00000003410.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 170.244 bits (430), Expect = 2.770e-48
Identity = 101/247 (40.89%), Postives = 138/247 (55.87%), Query Frame = 2

Query: 1601 LHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKI-SKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDF 2338
            LH+K+HLC+ +TR LLLSTY+KF+NLFPEIK  IQ++L++ + LRNAD E+QQR +EYL LS +AT DV+ATVLEEMP F ERESSIL                        AK+  K    T  D    K+   + +V  L  +   S P+ + S       +       G G    ++          L    SDE + K + K++G+LFEN  +QIG+KSE+R N+GR+ +FYGNK+  Q   F
Sbjct:    1 LHSKFHLCSVSTRALLLSTYIKFVNLFPEIKPTIQEVLRSGNQLRNADAELQQRAVEYLKLSTVATTDVLATVLEEMPPFPERESSIL------------------------AKLKKKKGPSTVTDLEDGKKTGPVPDVFFLNVVSVQSTPSPSASADLLGLGAPPPGGGGGGGGGLLVDVFSDIGTAAALPSISSDEYFAKFVCKNNGVLFENQLLQIGVKSEYRQNLGRVCLFYGNKTSVQFQSF 223

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BLAST of AP-2 complex subunit alpha vs. Ensembl Sea Lamprey
Match: ap3d1 (adaptor related protein complex 3 subunit delta 1 [Source:ZFIN;Acc:ZDB-GENE-050208-437])

HSP 1 Score: 133.265 bits (334), Expect = 7.629e-32
Identity = 128/529 (24.20%), Postives = 251/529 (47.45%), Query Frame = 2

Query:   38 VKG--DSM--RGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDC-------DPNLLIRACNQ-LGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESAD-YSIREEMVLKVA-ILSE---KYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTV---FEALQAPACHEN------MVKVGGYILGEF 1546
            VKG  D M  + L   +  IRN   KE E K + + +  I+ + K D       K   V KL ++ +LG+D+ +G    + ++ S K+T K++GYL  S   +E  +++ L    ++ DL+S+N     +AL  ++   T ++  + A ++  L+ S  T   V++ A L + K+    P+         R+   L D    + +AAV++I  L +R+P+ Y +   L      +++TSS  +            W+ +K+++L     P             LE  L K    P +  + HS +  ++L+E +N +I +         D +  I+ C Q L   +   + NL+YL L +M  +  +    ++V+ H++ ++  L  ++D S+R R++DLLY M  + N  EIV  ++ +++ A+  + R+E++ K+  I S+   ++ T++ WYV  ++ L R+ G      +  +V+ + I    ++ +  + +    + +  PA +        ++    +I GEF
Sbjct:    6 VKGSLDRMFDKNLQDLVRGIRN--HKEEEAKFVAQCIEEIKHELKQDNI---NVKGNAVAKLAYLQMLGYDVSWGAFNIIEVMSSGKFTHKRVGYLAASQSFHEGTDVLMLTTNMIRKDLNSQNQYDAGVALTGVSCFITPDLARDLANDLMTLMSS--TRPYVRKKAVLIMYKVFLKYPE--SLRPAFPRLKEKLEDPDPDLKSAAVNVICELARRNPKNYLSLAPL----FFKLMTSSTNN------------WVLIKIIKLFGALTP-------------LEPRLGKKLIEPLTNLI-HSTSAMSLLYECVNTVIAVLISLSSGMPDHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILRTH--PKSVQSHKDLILQCL-DDKDESIRLRSLDLLYGMVSKKNLMEIVKRLMVHMDKAEGTTYRDELLTKIIDICSQSNYQHVTNFEWYVSILVELTRLEGTRHGHLIAEQVLDVAIRVRAIRAFGVRQMALLLDNVHVPASNGQRNGICEVLYAAAWICGEF 492

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BLAST of AP-2 complex subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007788.1 (pep scaffold:Pmarinus_7.0:GL482991:1901:4831:1 gene:ENSPMAG00000007042.1 transcript:ENSPMAT00000007788.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.457 bits (267), Expect = 1.889e-27
Identity = 48/122 (39.34%), Postives = 78/122 (63.93%), Query Frame = 2

Query: 2519 IMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            I + LP+ +NKF +   M    FF RWK L  P QE Q + K+   PMEL V + +L G  +++L  +DP   N+V +GI+   + ++G LLRLEPN+  ++YRLT+R++K+ VS+++  ++
Sbjct:   20 ITMQLPVVLNKFFQPTEMASQDFFTRWKQLSSPQQEAQRIFKATT-PMELEVTKAKLVGFGMAMLERVDPNPDNYVGAGIIQTKTLQIGCLLRLEPNLQAQMYRLTLRTSKESVSKRLCELL 140

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BLAST of AP-2 complex subunit alpha vs. Ensembl Yeast
Match: APL3 (Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport [Source:SGD;Acc:S000000133])

HSP 1 Score: 239.195 bits (609), Expect = 4.382e-66
Identity = 193/671 (28.76%), Postives = 336/671 (50.07%), Query Frame = 2

Query:   50 SMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKT-------LDGYQKKKYVCKLLFIFLLGH-----DIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNL---VVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKE------IPRLLVSGDTIDSVKQSAALCLLKLIRA-----APDLVHFDDWTSRVIHLLND-QHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIV-------TSSYTDLQ---DYTYYFVPAPWLSVK---LLRLLQNYPPPDDA-----------PVRSRLTECLESIL---SKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATS--EFSHEAVK-KHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLES----ADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYV--SEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIA----TDDVMATVLEEMPSFTERESSI 1861
            +++GL +FI+D+R+ +  + + KRI  E+  I+  F   K        L GYQ+KKYV KL +I++  +     +I FG  + V LL S+ ++EK IGY+ + +L   S  +  +   V  +L  DLSS +  FV LAL  +  +G  E+T   A        + ++L S  +   +K+ +AL  L L+++       DL     W  R++ LL+D ++  +  A + LIE + K     Y  C  L + +L+ I+       TS  +D Q   +YT+  +P PWL  K   LL +L   P   D+            + ++L +C+   +   ++  + P  + VQ     N VLF  IN    +D     +  +   L   L+ +E N+RYL L+S+  L +S  + + +AV+ K+ + +   L +ERD S+ ++ VDLLY   D  N + IV  +L Y+ S    A+  I+ ++ +K+AIL+EKYATD +W+V   L L+ +  +     +E+W R+ QIV+N   +   + + + + L      E ++K   ++LGE+ +LI  D  SS  + F +   KY       + ++L+T +K     PEI   +    + +  L + D+E+Q R+ EYL + ++A      D++  + E MP F  + + +
Sbjct:   18 TIKGLQLFIADLRSAQQAQEQEKRIQSEIVKIKQHFDAAKKKQGNHDRLGGYQRKKYVAKLAYIYITSNTTKLNEILFGLEQTVELLKSSIFSEKFIGYMTLELLYERSEVVAKVNDEVNYQLMKDLSSSDDNFVMLALNFVGVVG--ELTNRLAYNDDITTGVFKILRSPTSSIYLKKKSALSFLALLKSNHSILTEDLQRKQLWIQRILSLLDDTENYRLTLATIPLIEFIAKYIDPSY--CTRL-LPQLTEILYNCVVVGTSRSSDNQFPLEYTFANMPNPWLITKVVSLLSILIASPTERDSGSLLQTNNIDNELLNKLRKCVSVAIELGTRQAQDPMERIVQ-----NTVLFSLINFASKLDPSDEAISNSVTALCSLLTSKEINIRYLTLDSLVKLCSSSGKPAIDAVRYKNLDMIFHLLNTERDSSIVRKVVDLLYTFTDVENVKIIVDGLLQYILSPKNLAEPQIKSDIAVKIAILTEKYATDINWFVIISLQLLSLTSNTTINDDEIWQRLCQIVVNNPSLHRITCERLVDYLCKKQASEAIIKAAAFLLGEYSSLIT-DRISSANL-FTLFAEKYFSAPNVAKAMILTTMIKLYKTSPEIGSNVIKFFQLE--LNSLDIELQTRSFEYLNIIQLAKVNGNTDILQILFEPMPPFNSKSNPL 674

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BLAST of AP-2 complex subunit alpha vs. Ensembl Yeast
Match: APL4 (Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport [Source:SGD;Acc:S000006233])

HSP 1 Score: 117.857 bits (294), Expect = 1.679e-27
Identity = 114/482 (23.65%), Postives = 245/482 (50.83%), Query Frame = 2

Query:   44 GDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHM---GVVTAAVSLIESLV------KRSPEEYKACVSLA---VSRLSRIVTSSYTDLQD---------YTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLES---ILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYAT----DYSWYVDTILNLIRVAGDYVSEE 1405
            G S+R    FI D+R  K+   E   I ++ A IR+K + D  L   +++  + KLL++++LG    FG  E++NL+ S+ + +K++GYL  ++L++ES +L+ L+   L +DL   N   V+LAL  +  + + E+  +   ++  ++ +      +K+ A  C  KLI     L+   +    +  +L+   +   GV+     +I+S++      K+  +E +  +  +   +S LS ++   +  L++         Y    +  P+L  +++  L+ Y    +    + + +  ++   +L++      S K    N+  A+L+E +  I  +D +  L +   N L +FL+ ++ N +Y++L ++  +   E +  AV++H++ +   L+ + DVS+R RA++L +A+ D +N  E+V E++ +L   D   ++ ++  +  L + + T    D SW +D   N++++ G +++ E
Sbjct:    2 GSSLRS---FIKDVRGAKTLADERAIITKQSAKIRTKLRDDH-LPHEKRRVNIQKLLYLYILGEKTHFGQVESINLIASDDFVDKRLGYLAATLLLDESEDLLTLLTNMLNNDLHHPNKYAVSLALTSLGFLSSPELARDLYPDVENIIKNSRDPFLLKK-ALQCAAKLIFKDVSLLEIFN-IEDITKILSSHSICTHGVLLGVTKIIQSILLIGLNRKKDEDEDEDGIDYSNDILSPLSLLLRDFFIRLENMNSKNIEPGYDVQGICDPFLQCEIIYTLKLYFQVGELLNSNNVLDYKDNFCDLLTRIATNTDSTK----NSGQAILYETVKTIFSLDLNQPLRVLGINILAKFLAGKDNNTKYVSLNTLLKVVPQEPT--AVQRHRKFISHCLQ-DTDVSIRMRALELSFAILDDSNLVELVNELMKFLAKQDEDSKDLIIYTIDHLIDTFDTRVVKDESWKLDVFFNILKLVGSFINYE 470

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BLAST of AP-2 complex subunit alpha vs. Ensembl Yeast
Match: APL5 (Delta adaptin-like subunit of the clathrin associated protein complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; suppressor of loss of casein kinase 1 function; the clathrin associated protein complex is also known as AP-3 [Source:SGD;Acc:S000006116])

HSP 1 Score: 93.9745 bits (232), Expect = 5.534e-20
Identity = 131/616 (21.27%), Postives = 278/616 (45.13%), Query Frame = 2

Query:  176 DGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDL---SSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLV--HFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIH---MDCDPNLLIRAC-NQLGQFLSHRETNLRYLALESMCLL--ATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESAD------------------------YSIREEMVLKVAILSEKYAT--DYSWYVDTILNLIRVAGDYVSEEVWHRVIQ----IVINRSDVQGYSAKTVFEALQAPACHENMVKVGG---YILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVK----FINLFP-----EIKEEIQDILKNDSNLR-NADVEIQQRTIEYLTLSKIA-------TDDVMATVLEEMPSF 1840
            D   K   V KL ++ + G D+ + +   + ++ SNK  +K++GYL  S    +  +++ L    LK DL    + + V V +AL  ++ I T  +  + A ++  +L S  T   +++ A   L K+    P+ +  +FD + S+    L+D  + VV+AAVS+I  L K++P+ +   + L+      +VT             +   W+ ++LL+L  N      + V  +L         +A+  PK  ++  S    +V++E++N I+    ++ D      AC  +L  F   ++ NLRY++    C+L     + + + + +  + +I  L S+ DVS+R +A++L+  + D +N + IV  ++      D                        Y I+   V+     ++ Y++  D+ WY   I++L  +  D   + +  ++ +    ++I    ++  +   + + +     ++ +  V     + LGEF  L+      +  I+    +  Y+  + + +++L+   VK    + N F      EIK  ++++++   NL  ++  E+Q+R++E L   +++       T+ +   + E +PSF
Sbjct:   63 DLNSKTNAVLKLTYLEMYGFDMAWCNFHILEVMSSNKLQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDGNNDVVKVGIALSGLSTIITPSLARDIADDLFTMLNS--TRPYIRKKAITALFKVFLQYPEALRDNFDKFVSK----LDDDDISVVSAAVSVICELSKKNPQPF---IQLSPLLYEILVT-------------IDNNWIIIRLLKLFTNL-----SQVEPKL---------RAKLLPKILELMESTVATSVIYESVNCIVKGNMLEEDDFETAMACLERLHTFCDSQDPNLRYIS----CILFYKIGKINTDFISRFDQLIIRLL-SDVDVSIRSKAIELVEGIVDEDNLKAIVQTLMKQFVDEDVVILQTGSIVYEKSKRIPIIIPENYKIKMVNVIISICSADNYSSVNDFEWYNAVIMDLAMLCQDISDKSLGSKIGEQFRNLMIKVPSMREVTIANIIKLISNDNINKQLPTVLRECIWCLGEFSTLVEN---GNDLIKIMTENISYY--SHSVQEVLILALVKVFSNWCNNFQEDKRFEIKMVLKELIEFFENLSYSSTFEVQERSVEVLEFLRLSLEALEEDTEGLPMLLSEVLPSF 632

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BLAST of AP-2 complex subunit alpha vs. Ensembl Nematostella
Match: EDO49151 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH33])

HSP 1 Score: 1182.55 bits (3058), Expect = 0.000e+0
Identity = 601/964 (62.34%), Postives = 742/964 (76.97%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQ--NDSPATK------EEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI---LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMS-SQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP VKG+ MRGLAVFISDIRNCKSKEAEIKRIN+ELANIR+KFKGDK LDGYQKKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL++ +  L+ L+VQ +K+DLSSRN +FV LALQCIANIG +EM +    E+P+LLVS DT DSVKQ AALC+LKL R   +L+   +WTSR++ LLND+H+GVVT+A SLI+ LV++SP+EYK C+ LAVSRLSRIVTSSYTDLQDYTYYFVPAPWL +KL++LLQ YPPPDD  + +RL ECL++IL+KAQEPPKSKKVQHSNA+NAVLFEAINLIIHMD D +LLIR CNQLGQFL+HRETNLRYLALE +CL++ SEFS +AV+KHQETV+ ALK+ERDVSVRQRAVDLLYAMCD+NNAEEIV EML YLE+ADYSI+EEMVLKVAILSEKYATDYSWYVDTIL LIR+AGDYVSEEVW+RVIQIVINR D+QGY+AKTVFEALQ PACHENMVKVGGYILGEFGNLIAGDPRSSP +QFQ+LH+K+ LC  +TR LLLSTY+KFINLFPEIK  IQ+IL++DSNLRN+D EIQQR +EYL LS +A+ DV+ATVLEEMP F ERESSILAKLK+KKP A++ ++     + PT    K + + Q  N +P  K        PA+Q  DL+GG+ S        S  T    + LL+D+    F++    +  ST  +T+ Q  ++E   K + K++G+L+E+D IQIG+KSEF+   GR+G+F+GNK+  Q  +F   +    P  +   LK + + +   I  G Q QQ + +EC + F Q   + + F++   S + +L +PI + KF  S  M+   FF RWK L  P QECQ + ++ K PME   + T+L G  L++ + +DP   NFV +GI+ M  + +VG LLRLEPN   K+YRLT+RS++  V+  +  ++
Sbjct:    1 MPAVKGEGMRGLAVFISDIRNCKSKEAEIKRINKELANIRNKFKGDKQLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVSANSELIKLIVQSIKNDLSSRNAIFVCLALQCIANIGNQEMVDQLGSEVPKLLVSPDTSDSVKQCAALCVLKLFRLNENLLPPGEWTSRIVQLLNDKHLGVVTSATSLIQGLVQKSPDEYKGCIQLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLCIKLIKLLQMYPPPDDPAISARLHECLDTILNKAQEPPKSKKVQHSNARNAVLFEAINLIIHMDSDQSLLIRGCNQLGQFLTHRETNLRYLALEGLCLMSNSEFSVDAVRKHQETVMGALKTERDVSVRQRAVDLLYAMCDKNNAEEIVSEMLEYLETADYSIKEEMVLKVAILSEKYATDYSWYVDTILTLIRIAGDYVSEEVWYRVIQIVINRDDIQGYAAKTVFEALQHPACHENMVKVGGYILGEFGNLIAGDPRSSPMVQFQLLHSKFPLCASSTRGLLLSTYIKFINLFPEIKPYIQEILRSDSNLRNSDAEIQQRALEYLKLSTVASPDVLATVLEEMPPFPERESSILAKLKKKKPNAVKERD-----EKPTDSSDKPTTNGQVSNAAPQVKVNAQPTPSPAMQ-ADLIGGIGS--------SAPTPAGGAGLLVDV----FET---PSPVSTGALTMTQG-AEEMLQKFVIKNTGVLYESDIIQIGVKSEFKEVEGRVGLFFGNKTSSQFVNFTATI--QMPDDLGERLKAESSQVTPVIEGGAQVQQLITVECVKDFYQCPFIVIQFSVNGISQQFVLKVPIFLAKFFTSVEMNSQDFFTRWKGLSSPQQECQKIFQA-KYPMESGTIATKLSGFGLAIQNGVDPNPENFVCAGIIKMKVAGQVGCLLRLEPNRQAKMYRLTLRSSRPEVATHLCELL 939

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Nematostella
Match: EDO41985 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2T7])

HSP 1 Score: 259.61 bits (662), Expect = 2.124e-75
Identity = 167/602 (27.74%), Postives = 332/602 (55.15%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQ----------ILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPS 1837
             I  IR  ++   E   I++E A IR  F+ +   D   + + V KLL++ +LG+   FG  E + L+ S K+T+K+IGYL   +L++E  ++  LV   +K++++  N   V LA+  + +I ++EM+ + A EI +L+ S ++   +++ A LC  ++IR  P+L+     ++R   L+++++ GV+   ++L+  + K + E    +K  V   V  L  ++ S Y+   D +   +  P+L V+++RLL+     D+       +E +  +L++     ++ K    N  NA+L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL +  LL T +  + AV++H+ T++  LK + D+S+R+RA++L +A+ + +N   ++ E++S+L+ AD   +  +   +  +++KY+    W++DT++ ++  AG++V ++    +I +V   SD+Q Y  + +F+A+Q     +++V+VG +  GE+G+ +  D      +             +L++ +   T TTR   L+  +K    F    E I+ +L+      + D+E+QQR +EY+TL K   D++   +LE+MP+
Sbjct:   10 LIRTIRAARTAADERAVISKECAAIRDSFREE---DNDFRCRSVAKLLYVHMLGYPAHFGQLECLKLIASPKFTDKRIGYLGAMMLLDERQDVHLLVTNSMKNNMTHSNQFVVDLAMCALGSICSQEMSRDLAGEIEKLIKSSNSY--LRKKATLCATRIIRKVPELMEIFVPSTR--SLISERNHGVLLTGITLVTVMCKLNTETLQHFKRHVPTLVKTLKNLIMSGYSPEHDVSG--ISDPFLQVQIIRLLRILGKDDEET-----SEQMNDVLAQVATNTETSK----NVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALNT--LLRTVQADYNAVQRHRSTILDCLK-DPDISIRRRAIELSFALVNSSNIRGMMKELISFLDKADEEFKSYVTSNIFEVADKYSPSKRWHIDTMMKVLTTAGNFVRDDTVPHLIHLVSTSSDLQAYGVQQLFKAMQHDISQQSLVQVGSWCCGEYGDKLLVDIEEDEPLGITENDVLDVLECVLYSSH--STSTTRDYALTAIMKLSTRFTTSTERIKSLLERFGC--SMDMELQQRGVEYITLFK-KYDNMRPALLEKMPA 585

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BLAST of AP-2 complex subunit alpha vs. Ensembl Nematostella
Match: EDO49859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7REW0])

HSP 1 Score: 156.377 bits (394), Expect = 1.433e-39
Identity = 139/599 (23.21%), Postives = 279/599 (46.58%), Query Frame = 2

Query:   41 KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYL-ESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSD-------VQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKY--HLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILK-----NDSNLRNADVEIQQRTIEYLTLSKI 1792
            +  + R   + +  I   KSK  E + I  E   ++ K     +    Q ++++ +L++  +LG D    H  A+N        +K+IGYL +S+ ++E+H L+ L+V  L+ DL S N + +  AL     +   EM     +++  LL      D V++ A + L +L +  P +V   +     +  L+D+  GV ++++ +   L+  +P ++K  V   V+ L + V S   D Q + Y+ +P PW+ +KLL++       DD  V S++ + +   +S             +    A+ +E    I  +  +  L+ +A   +G FL  +  +++YL + ++  L     S       Q  +I  L  + D  ++++ +DLL  + +  N E +  + L +L  + D   R E+V +V  L+E+YA D SWY+ T+  ++ + GD V  +V + +++++    D       ++ ++  +  + L+ PA  + ++ V  ++LGE+  ++     S P    + LH+     L    T++ ++S   K +     I + +   L       D +LR    EIQQ + +   ++K+
Sbjct:   19 RSSASRAFQLLVRGIGEAKSKHEEERIIREEFLVLKQKISQPSS--PKQMREFLVRLIYCEMLGIDASDLHIHAINFAQQQNMMDKRIGYLALSLFLHENHPLLVLLVNTLQRDLKSTNVLVIMSALTAFCKLINTEMVPAVLQQVLSLL--DFKRDIVRKKAVMALHRLHQKCPSMV--SNIEEHALKALHDRDFGVFSSSLHIFYDLIFENPMKFKHLVQDFVN-LQQKVISGKLDKQ-FEYHNIPGPWIQIKLLKIFA-LLGTDDQKVSSQMYDVINKTISSLS--------TGALIGYAIAYECCRTITLIYPNKQLITKAGKAVGLFLVAKSNDIKYLGITALAALVQVNASLATEAAFQLIIIDCL-DDPDEMLKRKTLDLLCRITNATNVETVCDKFLQHLRHTNDAHFRSELVARVTELAERYAPDNSWYILTMNEVLELGGDLVRPDVAYNLMRLIAEGHDDEELDDELRRFAVLSYLDLLEKPALPDILIHVICWVLGEYSYIV-----SEPNTVLEQLHSLLDGKLKDSKTKRWVVSAMGKLVAQIGRIPDSVAGALAKCRADGDVDLRQRVYEIQQLSCDPNLMAKV 594

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BLAST of AP-2 complex subunit alpha vs. Ensembl Nematostella
Match: EDO38269 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDJ0])

HSP 1 Score: 141.739 bits (356), Expect = 1.202e-34
Identity = 123/486 (25.31%), Postives = 241/486 (49.59%), Query Frame = 2

Query:   56 RGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLL---------IRAC-NQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESAD-YSIREEMVLKVAILSE----KYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAK 1468
            + L   +  IRN K  EA  K +   L +I+++ + +   +   K   V KL ++ +LG+DI +     + ++ S+K+T K+IGYL  S   +E  +++ L    ++ DL S N     +AL   +   T ++  + A ++  LLVS  T   +++ + L + K+    P+ +       R+   L D   GV +AAV++I  L +++P+ Y +   L      +++TSS  +            W+ +K+++L     P             LE  L K    P +  + HS +  ++L+E IN +I +  D + L         I+ C ++L   L   + NL+YLAL +M  +  +    +AV+ H++ +I  L  ++D S+R RA+DL+  M  + N  +I+ +++ +++ AD  + R+E++ K+ ++      +Y T++ WYVD ++ L R+ G    ++V  +++ + I    V+ Y+ +
Sbjct:    5 KNLTDLVRGIRNNKDNEA--KYVASCLDDIKTELRQE---NASIKANAVAKLAYLEMLGYDISWAAFNIIEVMSSSKFTYKRIGYLAASQSFHEGLDILMLTTNMIRKDLCSMNMYDSGVALAGFSCFVTPDLARDLANDVMSLLVS--TKPYIRKRSILLMYKIFLKFPEALR--PAFPRLREKLEDPEPGVQSAAVNVICELARKNPKNYLSLAPL----FFKLMTSSTNN------------WMLIKIIKLFGALCP-------------LEPRLGKKLLEPLTNLI-HSTSAMSLLYECINTVICVLIDLDSLLGLSDHQPSIQLCVSKLRLLLEDPDQNLKYLALLAMSKILKTH--PKAVQSHKDIIIHCL-DDKDESIRLRALDLVVGMVSKKNIMDIIKKLMIHIDKADSQNYRDELLSKIIMICSQGDYQYVTNFEWYVDVLIQLTRIEGTRYGKQVAAQMMDVTIRVKAVRPYAVQ 448

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Nematostella
Match: EDO36135 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJK8])

HSP 1 Score: 70.0922 bits (170), Expect = 3.899e-12
Identity = 129/604 (21.36%), Postives = 254/604 (42.05%), Query Frame = 2

Query:  131 ELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLII-HMD-CDP------NLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAK------TVFE---ALQAPACHENMVKVGGYILGEFG-----------NLIAGDPRSSPQIQFQILHA--KYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMA--TVLEEMPSFTE 1846
            E+  ++++   DK     +KK+ V K++    +G D+     + VN + ++    K++ YL++        ++  + V     D    NP+   LA++ +  I   ++TE   + + + L   D    V+++AA+C+ KL      LV    +   +  LL+D +  VV  A++ +  +   SP    A + +    +++++T+    L + T       W  + +L  L  Y P D+           +SI  +      + ++ H+NA  AV+  AI +++ +M+   P      N+L +    L   LS  E  ++Y+AL ++ L+       E +K   +     +K    + V+   +D++  + +  N  +++ E+  Y    D     + V  +   + K        V T+L+LI+   +YV +E       IV+ +   + Y  K      T+ E   +L  P    +M+    +I+GE+            + + G    + Q+Q Q+L +  K  L  PT  Q              E+ +++  +   DS+  N D+    R   Y+    ++TD V A   VL E P  +E
Sbjct:   14 EIFELKAELNSDKK---DRKKEAVKKVIASMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPY--VRKTAAVCVAKLHDINAQLVEDQGFLDSLKELLSDSNPMVVANAMAALSEINDASPTA-AAMMEMNSQTINKLLTA----LNECTE------WGQIFILDSLAQYTPKDEREA--------QSICERV-----TPRLSHANA--AVVLSAIKVLMKYMEMMTPSTGFVQNILKKLAPPLVTLLSS-EPEVQYVALRNINLIVQKR--PEILKNEMKVFF--VKYNDPIYVKLEKLDIMIRLANELNIAQVLAELKEYATEVDVDFVRKSVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEA------IVVIKDIFRKYPNKYESIISTLCENLDSLDEPEARASMI----WIIGEYAERIDNAAELLESFLEGFQDENTQVQLQLLTSIVKLFLKRPTDTQ--------------ELVQQVLSLATQDSD--NPDL----RDRGYIYWRLLSTDPVAAKEVVLAEKPLISE 551

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Medaka
Match: ap2a1 (adaptor related protein complex 2 subunit alpha 1 [Source:NCBI gene;Acc:101174026])

HSP 1 Score: 1207.2 bits (3122), Expect = 0.000e+0
Identity = 603/963 (62.62%), Postives = 717/963 (74.45%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQ-------EVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI---LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L + +PDLV   +WTSRV+HLLNDQHMGVVTAA+SLI  L +++P+E+K CVSLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLS KLLRLLQ YPPP+D  V+ RL ECLE+IL+KAQEPPKSKKVQHSNAKNA+LFEAI LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EMLSYLE+ADYSIREEMVLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLS Y+KFINLFPE K  IQ++L+ DS +RN+DVE+QQR +EYL LS IA+ DV+ATVLEEMP F ERESSI       K    +G   ++  +    K     L+   D        A           DLLG              +       LL+D+             S   P     + +DE +L+ + K++G+LFEN  +QIGIKSE+R N+GR+ +FYGNK+  Q   F T +  S P  +   L +   P++  +  G Q QQ LNIEC   F +   L + F        + L LP+TINKF +   M    FFQRWK L QP QE Q + K+    M+  VL+ +L GL +++L N+DP   N+V +G++    Q+VG LLRLEPN   ++YRLT+R +KD VSR++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMCLALHCIANVGSREMAEAFASEIPRILVAGDTMDSVKQSAALCLLRLYKTSPDLVLMGEWTSRVVHLLNDQHMGVVTAAISLITCLSQKNPDEFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSCKLLRLLQCYPPPEDGAVKGRLVECLETILNKAQEPPKSKKVQHSNAKNAILFEAIALIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVAEMLSYLETADYSIREEMVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPLVQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPETKATIQEVLRCDSQIRNSDVELQQRAVEYLKLSSIASTDVLATVLEEMPPFPERESSI-----LAKLKKKKGPGAVSVTEMEDGKREGGELNGGGDRGPDASAMAASNASTPSPSADLLG------IRPAAPVSAAPASVGSLLVDVF------------SEAGPAASSAAVNDEGFLRFVCKNNGVLFENQLLQIGIKSEYRQNLGRMYLFYGNKTSVQFASFTTTV--SYPGELQSQLNVQSKPVEPLVEGGAQIQQVLNIECLTDFSEAPLLNIKFRYGGALQNLTLKLPVTINKFFQPTEMASQDFFQRWKQLSQPQQEAQKIFKA-NNSMDTEVLKAKLLGLGMALLDNVDPNPENYVCAGVIQTKGQQVGCLLRLEPNAQAQMYRLTLRCSKDSVSRRLCELL 937

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Medaka
Match: ap2a1 (adaptor related protein complex 2 subunit alpha 1 [Source:NCBI gene;Acc:101174026])

HSP 1 Score: 1206.05 bits (3119), Expect = 0.000e+0
Identity = 612/987 (62.01%), Postives = 730/987 (73.96%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSI-----------XXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPAT----------KEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQ----------PTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI---LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L + +PDLV   +WTSRV+HLLNDQHMGVVTAA+SLI  L +++P+E+K CVSLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLS KLLRLLQ YPPP+D  V+ RL ECLE+IL+KAQEPPKSKKVQHSNAKNA+LFEAI LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EMLSYLE+ADYSIREEMVLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLS Y+KFINLFPE K  IQ++L+ DS +RN+DVE+QQR +EYL LS IA+ DV+ATVLEEMP F ERESSI              + + +    EG EL           +  + +    SP+                     LL  +FS + P  +++    +           TSD LL + G+G DSD         P     SE+DE   K + K++G+LFEN  +QIGIKSE+R N+GR+ +FYGNK+  Q   F T +  S P  +   L +   P++  +  G Q QQ LNIEC   F +   L + F        + L LP+TINKF +   M    FFQRWK L QP QE Q + K+    M+  VL+ +L GL +++L N+DP   N+V +G++    Q+VG LLRLEPN   ++YRLT+R +KD VSR++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMCLALHCIANVGSREMAEAFASEIPRILVAGDTMDSVKQSAALCLLRLYKTSPDLVLMGEWTSRVVHLLNDQHMGVVTAAISLITCLSQKNPDEFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSCKLLRLLQCYPPPEDGAVKGRLVECLETILNKAQEPPKSKKVQHSNAKNAILFEAIALIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVAEMLSYLETADYSIREEMVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPLVQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPETKATIQEVLRCDSQIRNSDVELQQRAVEYLKLSSIASTDVLATVLEEMPPFPERESSILAKLKKKKGPGAVSVTEMEDGKREGGELNGGGDRGPDASAMAASNASTPSPSADLLGIRPAAPVSAAPASVGSLLVDVFSEAGPAASSAAVNDEGFLRDLEPPTETSDSLL-VEGSG-DSDSAPPSEDPAP---PLSEADELLNKFVCKNNGVLFENQLLQIGIKSEYRQNLGRMYLFYGNKTSVQFASFTTTV--SYPGELQSQLNVQSKPVEPLVEGGAQIQQVLNIECLTDFSEAPLLNIKFRYGGALQNLTLKLPVTINKFFQPTEMASQDFFQRWKQLSQPQQEAQKIFKA-NNSMDTEVLKAKLLGLGMALLDNVDPNPENYVCAGVIQTKGQQVGCLLRLEPNAQAQMYRLTLRCSKDSVSRRLCELL 979

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Medaka
Match: ap2a1 (adaptor related protein complex 2 subunit alpha 1 [Source:NCBI gene;Acc:101174026])

HSP 1 Score: 1203.73 bits (3113), Expect = 0.000e+0
Identity = 607/977 (62.13%), Postives = 725/977 (74.21%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSI-----------XXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPAT----------KEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTI---LKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAEIKRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N +  L+ L+   +K+DLSSRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GDT+DSVKQSAALCLL+L + +PDLV   +WTSRV+HLLNDQHMGVVTAA+SLI  L +++P+E+K CVSLAVSRLSRIV+S+ TDLQDYTYYFVPAPWLS KLLRLLQ YPPP+D  V+ RL ECLE+IL+KAQEPPKSKKVQHSNAKNA+LFEAI LIIH D +PNLL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVI+ALK+ERDVSVRQRA DLLYAMCDR+NA++IV EMLSYLE+ADYSIREEMVLKVAIL+EKYA DYSWYVDTILNLIR+AGDYVSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLS Y+KFINLFPE K  IQ++L+ DS +RN+DVE+QQR +EYL LS IA+ DV+ATVLEEMP F ERESSI              + + +    EG EL           +  + +    SP+                     LL  +FS + P      ++S   +D        GF S    ++    P+    SE+DE   K + K++G+LFEN  +QIGIKSE+R N+GR+ +FYGNK+  Q   F T +  S P  +   L +   P++  +  G Q QQ LNIEC   F +   L + F        + L LP+TINKF +   M    FFQRWK L QP QE Q + K+    M+  VL+ +L GL +++L N+DP   N+V +G++    Q+VG LLRLEPN   ++YRLT+R +KD VSR++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLSSRNPTFMCLALHCIANVGSREMAEAFASEIPRILVAGDTMDSVKQSAALCLLRLYKTSPDLVLMGEWTSRVVHLLNDQHMGVVTAAISLITCLSQKNPDEFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSCKLLRLLQCYPPPEDGAVKGRLVECLETILNKAQEPPKSKKVQHSNAKNAILFEAIALIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVAEMLSYLETADYSIREEMVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPLVQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPETKATIQEVLRCDSQIRNSDVELQQRAVEYLKLSSIASTDVLATVLEEMPPFPERESSILAKLKKKKGPGAVSVTEMEDGKREGGELNGGGDRGPDASAMAASNASTPSPSADLLGIRPAAPVSAAPASVGSLLVDVFSEAGP-----AASSAAVND-------EGFLSSAPPSEDPAPPL----SEADELLNKFVCKNNGVLFENQLLQIGIKSEYRQNLGRMYLFYGNKTSVQFASFTTTV--SYPGELQSQLNVQSKPVEPLVEGGAQIQQVLNIECLTDFSEAPLLNIKFRYGGALQNLTLKLPVTINKFFQPTEMASQDFFQRWKQLSQPQQEAQKIFKA-NNSMDTEVLKAKLLGLGMALLDNVDPNPENYVCAGVIQTKGQQVGCLLRLEPNAQAQMYRLTLRCSKDSVSRRLCELL 958

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000022962.2 (AP-2 complex subunit alpha-2 [Source:NCBI gene;Acc:101164872])

HSP 1 Score: 1166.76 bits (3017), Expect = 0.000e+0
Identity = 585/956 (61.19%), Postives = 723/956 (75.63%), Query Frame = 2

Query:   29 MPTV-KGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTS--DLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPT-TILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNII 2884
            MP V KGD MRGLAVFISDIRNCKSKEAE+KRIN+ELANIRSKFKGDK LDGY KKKYVCKLLFIFLLGHDIDFGH EAVNLL SNKYTEKQIGYLFISVL+N + +L+ L+   +K+DL+SRNP F+ LAL CIAN+G+REM E FA EIPR+LV+GD++DSVKQSAALCLL+L R +PDLV  ++WT+RV+HLLNDQH+GVVTAA SLI +L ++SP+++K  VSLAV+RLSRIVTS+  DLQDYTYYFV APWLSVKLLRLLQ YPPP+D  +RSRLTECLE+IL+KAQEPPKSKKVQHSNA+NAVL EAI LIIH D +P LL+RACNQLGQFL HRETNLRYLALESMC LA+SEFSHEAVK H ETVISALK+ERDVSVRQRAVDLLYAMCDR+NA +IV EML YLE+ADYSIREE+VLKVAIL+EKYA DY+WYVDTILNLIR+AGD+VSEEVW+RVIQIVINR DVQGY+AKTVFEALQAPACHEN+VKVGGYILGEFGNLIAGDPRSSP +QF +LH+K+HLC+  TR LLLS Y+KFINLFPE+K  IQD+L++DS LRNADVE+QQR +EYL LS IA+ D++ATVLEEMP F ERESSILAKLK+KK +    +                  +   ++    EEPA           S   P +  + + + P +   LL+D+  +               ++   + ++++  + + K++G+L+E+  +Q+G+KSE+R N+GR+ +FYGNK+      F + + +S    T L +    ++  I  G Q QQ LNIEC   F     L V F        I + LP+ +NKF +   M    FFQRWK L  P QE Q + K+ + PME    + +L G  +++L  +DP  +NFV +GI++  S +VG LLRLEPN   ++YRLT+R+++D VS+++  ++
Sbjct:    1 MPAVSKGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSDLIRLINNAIKNDLASRNPTFMNLALHCIANVGSREMAEAFASEIPRILVAGDSMDSVKQSAALCLLRLNRTSPDLVPMEEWTARVVHLLNDQHLGVVTAATSLIITLAQKSPDDFKTSVSLAVTRLSRIVTSASIDLQDYTYYFVAAPWLSVKLLRLLQCYPPPEDTALRSRLTECLETILNKAQEPPKSKKVQHSNARNAVLLEAIALIIHHDSEPTLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVISALKTERDVSVRQRAVDLLYAMCDRSNARQIVAEMLGYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDHVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLVQFNLLHSKFHLCSVPTRALLLSAYIKFINLFPEVKATIQDVLRSDSQLRNADVELQQRAVEYLRLSCIASADILATVLEEMPPFPERESSILAKLKKKKGSGKLPE------------------NVNGNAELHAEEPAA------ANKASPPPPTEVLALNPTPPAAAHSLLVDVFSD---------------LSAPTAVAEDHLSRFVCKNNGVLYESQLLQVGLKSEYRQNLGRIYVFYGNKTSSSFLSFSSWVSSSDVLKTQLNVHAKAVEPVIEGGAQVQQVLNIECVTDFSDVPVLNVQFRYAGTLQNIEVKLPVMLNKFFQPTEMTSQDFFQRWKQLGAPQQEVQKIFKA-QHPMETDAAKAKLLGFGVALLEGVDPNPANFVGAGIIHSKSAQVGCLLRLEPNTHAQMYRLTLRTSRDSVSQRLCQLL 916

[Close]

BLAST of AP-2 complex subunit alpha vs. Ensembl Medaka
Match: ap1g1 (adaptor related protein complex 1 subunit gamma 1 [Source:NCBI gene;Acc:101160887])

HSP 1 Score: 264.233 bits (674), Expect = 8.971e-75
Identity = 178/600 (29.67%), Postives = 325/600 (54.17%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPE---EYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGN-LIAGDPRSSPQIQ------FQILHAKY--HLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMP 1834
             I  IR  +++  E + I +E A IRS F+ +   D   + + V KLL++ +LG+   FG  E + L+ S K+T+K+IGYL   +L++E  ++  L+   +K+DL+        LAL  +  +G+ EM  + A E+ +LL + ++   +++ AALC + +IR  P+L+    +     +LL++++ GV+  +V L+  + +RSP+    ++  V   V  L  ++ S Y+   D +   +  P+L V++LRLL+     DD       +E +  IL++     ++ K    N  NA+L+E +  I+ +  +  L + A N LG+FL + + N+RY+AL S  LL T +  H AV++H+ T++  LK + DVS+++RA++L +A+ + NN   ++ E+L +L+S D   + +    V + +EKYA    W++DTI+ ++  AG YV ++    +IQ++ N  ++  Y+ + +++AL      + +V+V  + +GE+G+ LI+G       IQ        +L      +L +P TR   L+  +K    F  +    + +    S++   DVE+QQR +EY  L K   D +   +LE MP
Sbjct:   24 LIRTIRTARTQAEEREMIQKECAAIRSSFREE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSY--LRKKAALCAVHVIRKVPELMEM--FLPATKNLLSEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSG--ISDPFLQVRILRLLRILGKGDDDS-----SEAMNDILAQVATNTETSK----NVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTS--LLKTVQTDHNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCDPEFKADCASGVFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDSVPNLIQLITNSVEMHAYTVQRLYKALLDDISQQPLVQVASWCIGEYGDLLISGQCEEEEPIQVTEDEVLDVLEGLLVSNLSSPVTRGYSLTAIMKLSTRFSSVNRIKKVVSIYGSSI---DVELQQRAVEYNALFK-KYDHMRPALLERMP 598

[Close]

BLAST of AP-2 complex subunit alpha vs. Planmine SMEST
Match: SMESG000036030.1 (SMESG000036030.1)

HSP 1 Score: 1943.7 bits (5034), Expect = 0.000e+0
Identity = 954/954 (100.00%), Postives = 954/954 (100.00%), Query Frame = 2

Query:   29 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSIXXXXXXXXXXXXEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIES 2890
            MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSILAKLKQKKPAALEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIES
Sbjct:    1 MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTERESSILAKLKQKKPAALEGQELIAPRQHPTAKISKNSLDTQNDSPATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDSDINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRGNMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQEQQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQNTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDPVASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFNIIES 954

[Close]

BLAST of AP-2 complex subunit alpha vs. Planmine SMEST
Match: SMESG000031293.1 (SMESG000031293.1)

HSP 1 Score: 234.572 bits (597), Expect = 2.232e-64
Identity = 168/633 (26.54%), Postives = 326/633 (51.50%), Query Frame = 2

Query:   71 FISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEE---YKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSK-AQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGGYILGEFGNL-------------IAGDPRSSPQIQFQILHAKYHLC-TPTTRQLLLSTYVKFINLFPEIKEEIQDI-----------LKNDSNLR-----------NADVEIQQRTIEYLTLSKIATDDVMATVLEEMPSFTER 1849
             + DIR+ ++   E   +NRE A IR  F+ +   D   + + V KLL+I +LG+   FG  + + L+ SNK+T+K+IGYL   +L++E  ++  LV   LK+DL+  N   V+LAL  + +I + EM+ +   E+ +L+ S +    +++ A LC  ++IR  PDL+      +R   LLN+++ GV+  A +LI  + ++SP+    ++  V   V  L  ++ S Y+   D     V  P+L VK+L+LL+     D        ++ +  IL++ A     SK V H     A+L+E +  I+ ++ +  L + A N LG+FL + + N+RY+AL +  L       ++AV++H+ T++  L  + DVS+++RA++L + + + +N   +  E+LS+L   +   + +    + + +EKYA + +W+ +T+L L+  AG+Y  ++V   ++ ++   S +  Y+   ++ AL      + ++++  + +GE+G               I  +P ++ +    ++      C TP +   LLS   K + L   + +  + I           LK +S+++           + ++E+QQR++E+ ++ +   D++   +LE MP    R
Sbjct:   10 LVRDIRSARTAAEERSVVNRECAQIRDNFREE---DSIYRCRNVAKLLYIHMLGYSAHFGQLDCLKLIASNKFTDKRIGYLGAMLLLDERTDIHVLVTNSLKNDLNHTNQYIVSLALCTLGSICSTEMSRDLVTEVEKLIKSSNAY--LRKKAILCAFRMIRKVPDLIELFIPATR--SLLNEKNHGVLITAATLITEMCQQSPDTLSFFRRMVPNLVRILKNLIMSGYSPEHDVN--GVSDPFLQVKVLKLLRIVGKGDHEA-----SDAMNDILAQVATNTDTSKNVGH-----AILYEIVLTIMGVESEAGLRVLAVNILGRFLLNNDKNIRYVALNT--LQQVVHVDYKAVQRHRSTIVDCLL-DPDVSIQRRAMELCFVLINTSNIRGMTKELLSFLHRCEPEFKADTCSSLVLAAEKYAPNKTWHFETMLQLLTTAGNYARDDVLSSLVALISQASAMHAYAVLRLYSALLYDMSQQPLIQIASWCIGEYGEYLITSQNITPPDDEINNEPVNNSENSGCVISISIPNCKTPVSENALLSVLEKAL-LSSSVTQYTKQIIQISLVKLSTRLKLESSIKLIRQLICVHSTSINLELQQRSVEFSSIFR-NYDNLRIGLLEAMPVMETR 618

[Close]

BLAST of AP-2 complex subunit alpha vs. Planmine SMEST
Match: SMESG000074044.1 (SMESG000074044.1)

HSP 1 Score: 148.288 bits (373), Expect = 5.828e-36
Identity = 146/596 (24.50%), Postives = 285/596 (47.82%), Query Frame = 2

Query:   56 RGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDCDPNLLIRACNQ-LGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYS-IREEMVLKVAILSEK----YATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEAL-----------QAPACHENMVKVGGYILGEFGNLIAGDPRSSPQ-IQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNAD--VEIQQRTIEYLTL 1783
            + L   +  IRN   KE E K I   L  I+++ K D       K   + KL+++ +LG+DI++     + ++ S K+T K+IGYL  +   +E  +++ L    ++ DL+S N     +AL  +A   T ++  + A +I  L+ S  T   +++ A L + K+    PD +       R+   L D   GV +AAV++I  L +++P+ Y   +SLA      + TS+               W+ +K+++L     P             LE  L K    P +  + HS +  ++L+E IN +I    D +  I+ C Q L   +   + NL+YL L +M  +  S    ++V+ H++ +++ L  ++D S+R RA+DLLY M  + N  EIV +++++++ A+ S  R E+++K+  ++ +    Y T++ WY+  ++ L R+ G    E +  +++ + I    V+ ++   +   L           Q+  C   ++    ++ GE+ + +    ++  Q IQ  I     H+ +     L+ +T   +  L  +++ EI   ++ D N+  +D  +E+ Q  ++ + L
Sbjct:   16 KNLQDLVRGIRN--HKEDEAKYIAECLDEIKNELKLDNL---AAKANAINKLIYLQMLGNDINWAAFNIIEVMSSTKFTYKRIGYLAAAQSFHEQTDVLMLTTNLIRKDLNSPNFYETGIALSGLACFITPDLARDLASDIMTLMTS--TKPYIRKKAVLLMYKVFLKFPDALR--PAFPRLKEKLEDPDPGVQSAAVNVICELARKNPKNY---LSLAPLFFKLMNTSNNN-------------WVLIKIIKLFGALTP-------------LEPRLGKKLIEPLTNLI-HSTSAMSLLYECINTVIAGIPDHSASIQLCVQKLRILIEDSDQNLKYLGLLAMTKILKSH--PKSVQTHKDLILNCL-DDKDESIRLRALDLLYGMISKKNIMEIVKKLMTHMDKAEGSHYRNELLIKIIEITSQNNYHYITNFEWYITILVELTRIDGIRNGELIAAQLLDVAIRVPTVRSFTVNQMANILHTSSELLANSKQSGVCE--VIYAAAWVCGEYADYLESPRKTLDQMIQTTIGSLPGHIQS----VLVQNTLKLYCRLLLKLESEIPSEIQLDENINPSDTCIELTQFVLDKMAL 563

[Close]

BLAST of AP-2 complex subunit alpha vs. Planmine SMEST
Match: SMESG000074044.1 (SMESG000074044.1)

HSP 1 Score: 142.895 bits (359), Expect = 2.908e-34
Identity = 146/603 (24.21%), Postives = 286/603 (47.43%), Query Frame = 2

Query:   56 RGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHMDC-------DPNLLIRACNQ-LGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYS-IREEMVLKVAILSEK----YATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEAL-----------QAPACHENMVKVGGYILGEFGNLIAGDPRSSPQ-IQFQILHAKYHLCTPTTRQLLLSTYVKFINLFPEIKEEIQDILKNDSNLRNAD--VEIQQRTIEYLTL 1783
            + L   +  IRN   KE E K I   L  I+++ K D       K   + KL+++ +LG+DI++     + ++ S K+T K+IGYL  +   +E  +++ L    ++ DL+S N     +AL  +A   T ++  + A +I  L+ S  T   +++ A L + K+    PD +       R+   L D   GV +AAV++I  L +++P+ Y   +SLA      + TS+               W+ +K+++L     P             LE  L K    P +  + HS +  ++L+E IN +I +         D +  I+ C Q L   +   + NL+YL L +M  +  S    ++V+ H++ +++ L  ++D S+R RA+DLLY M  + N  EIV +++++++ A+ S  R E+++K+  ++ +    Y T++ WY+  ++ L R+ G    E +  +++ + I    V+ ++   +   L           Q+  C   ++    ++ GE+ + +    ++  Q IQ  I     H+ +     L+ +T   +  L  +++ EI   ++ D N+  +D  +E+ Q  ++ + L
Sbjct:   16 KNLQDLVRGIRN--HKEDEAKYIAECLDEIKNELKLDNL---AAKANAINKLIYLQMLGNDINWAAFNIIEVMSSTKFTYKRIGYLAAAQSFHEQTDVLMLTTNLIRKDLNSPNFYETGIALSGLACFITPDLARDLASDIMTLMTS--TKPYIRKKAVLLMYKVFLKFPDALR--PAFPRLKEKLEDPDPGVQSAAVNVICELARKNPKNY---LSLAPLFFKLMNTSNNN-------------WVLIKIIKLFGALTP-------------LEPRLGKKLIEPLTNLI-HSTSAMSLLYECINTVIAVLISISSGIPDHSASIQLCVQKLRILIEDSDQNLKYLGLLAMTKILKSH--PKSVQTHKDLILNCL-DDKDESIRLRALDLLYGMISKKNIMEIVKKLMTHMDKAEGSHYRNELLIKIIEITSQNNYHYITNFEWYITILVELTRIDGIRNGELIAAQLLDVAIRVPTVRSFTVNQMANILHTSSELLANSKQSGVCE--VIYAAAWVCGEYADYLESPRKTLDQMIQTTIGSLPGHIQS----VLVQNTLKLYCRLLLKLESEIPSEIQLDENINPSDTCIELTQFVLDKMAL 570

[Close]

BLAST of AP-2 complex subunit alpha vs. Planmine SMEST
Match: SMESG000029126.1 (SMESG000029126.1)

HSP 1 Score: 62.003 bits (149), Expect = 2.155e-9
Identity = 107/504 (21.23%), Postives = 211/504 (41.87%), Query Frame = 2

Query:  227 LGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVLINESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEIPRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHMGVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQHSNAKNAVLFEAINLIIHM--------DCDPNLLIRACNQLGQFLSHRETNLRYLALESMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNNAEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIRVAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGG--------YILGEFG-----------NLIAGDPRSSPQIQFQILHA--KYHLCTPTTRQLLL 1651
            +G D+     + VN + ++    K++ YL++        +   L V     D    NP+   LA++ +  I   ++T      + + L   D    V+++AA+C+ KL      +V  + +   +  LL+D +  VV  AV+ I  +++ +  +  A   LA S+   +V    T L + T       W  V +L  + NY P DD+  +       E ++          ++ H+NA  AV+  A+ +I+ +        D    ++ +    L   LS  E  ++Y+AL ++ L+       E +K   E  +  +K    + V+   +D++  + +  N  +++ E+  Y +  D     + V  +   + K        + T+++LI+   +YV +E       IV+ +   + Y  K  +E++ A  C EN+  +          +I+GE+            + + G    + Q+Q Q+L A  K  L  P   Q L+
Sbjct:   70 VGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKTQPDTAILAVNTFVRDCDDPNPLIRALAVRTMGCIRVDKITAYLCDPLRKCLKDEDPY--VRKTAAVCVAKLYDIDATIVEDNGFLELLKDLLSDSNPMVVANAVAAISEILECTQSD-SAHQMLAFSQ--SVVNKLLTALNECT------EWGQVFILDAIANYQPKDDSEAQG----ICERVVP---------RLSHANA--AVVLSAVKVIMKLLEMLNPSDDFVQTMIKKLAPPLVTQLSA-EPEIQYVALRNINLIVQKR--SEILK--NEVKVFFVKYNDPIYVKLEKLDIMIRLTNHQNIPQVLAELKEYAKEVDVDFVRKSVRAIGRCAIKVEAAAERCMTTLIDLIQTKVNYVVQEA------IVVIKDIFRKYPNK--YESIIATLC-ENLDTLDEPEAKASMIWIIGEYAERIDNAEELLESFLEGFQDENTQVQLQLLTAIVKLFLKRPAHTQELV 533

The following BLAST results are available for this feature:

BLAST of AP-2 complex subunit alpha vs. Ensembl Human
BLAST of AP-2 complex subunit alpha vs. Ensembl Celegans
BLAST of AP-2 complex subunit alpha vs. Ensembl Fly
BLAST of AP-2 complex subunit alpha vs. Ensembl Zebrafish
BLAST of AP-2 complex subunit alpha vs. Ensembl Xenopus
BLAST of AP-2 complex subunit alpha vs. Ensembl Mouse
BLAST of AP-2 complex subunit alpha vs. UniProt/SwissProt
BLAST of AP-2 complex subunit alpha vs. TrEMBL
BLAST of AP-2 complex subunit alpha vs. Ensembl Cavefish
BLAST of AP-2 complex subunit alpha vs. Ensembl Sea Lamprey
BLAST of AP-2 complex subunit alpha vs. Ensembl Yeast
BLAST of AP-2 complex subunit alpha vs. Ensembl Nematostella
BLAST of AP-2 complex subunit alpha vs. Ensembl Medaka
BLAST of AP-2 complex subunit alpha vs. Planmine SMEST

BLAST of AP-2 complex subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AP2A2	0.000e+0	62.31	adaptor related protein complex 2 subunit alpha 2 ...	[more]
AP2A2	0.000e+0	62.41	adaptor related protein complex 2 subunit alpha 2 ...	[more]
AP2A1	0.000e+0	62.69	adaptor related protein complex 2 subunit alpha 1 ...	[more]
AP2A1	0.000e+0	61.59	adaptor related protein complex 2 subunit alpha 1 ...	[more]
AP2A2	0.000e+0	61.81	adaptor related protein complex 2 subunit alpha 2 ...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
apa-2	0.000e+0	60.52	AP-2 complex subunit alpha [Source:UniProtKB/TrEM...	[more]
apa-2	0.000e+0	60.52	AP-2 complex subunit alpha [Source:UniProtKB/TrEM...	[more]
apa-2	0.000e+0	60.52	AP-2 complex subunit alpha [Source:UniProtKB/TrEM...	[more]
apg-1	1.736e-73	29.30	AP-1 complex subunit gamma [Source:UniProtKB/TrEM...	[more]
apd-3	1.441e-31	24.33	AP-3 complex subunit delta [Source:UniProtKB/TrEM...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AP-2alpha	0.000e+0	63.77	gene:FBgn0264855 transcript:FBtr0089488	[more]
AP-2alpha	0.000e+0	63.38	gene:FBgn0264855 transcript:FBtr0089489	[more]
AP-1gamma	9.286e-62	29.27	gene:FBgn0030089 transcript:FBtr0333808	[more]
AP-1gamma	9.286e-62	29.27	gene:FBgn0030089 transcript:FBtr0071298	[more]
AP-1gamma	9.286e-62	29.27	gene:FBgn0030089 transcript:FBtr0071295	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ap2a1	0.000e+0	62.92	adaptor related protein complex 2 subunit alpha 1 ...	[more]
ap1g1	2.376e-74	29.33	adaptor related protein complex 1 subunit gamma 1 ...	[more]
ap1g2	7.470e-72	29.17	adaptor related protein complex 1 subunit gamma 2 ...	[more]
ap1g2	7.470e-72	29.17	adaptor related protein complex 1 subunit gamma 2 ...	[more]
ap2a1	1.054e-55	38.27	adaptor related protein complex 2 subunit alpha 1 ...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ap2a2	0.000e+0	64.05	adaptor related protein complex 2 subunit alpha 2 ...	[more]
ap2a2	0.000e+0	63.91	adaptor related protein complex 2 subunit alpha 2 ...	[more]
ap2a2	0.000e+0	63.74	adaptor related protein complex 2 subunit alpha 2 ...	[more]
ap2a2	0.000e+0	63.52	adaptor related protein complex 2 subunit alpha 2 ...	[more]
ap2a2	0.000e+0	63.96	adaptor related protein complex 2 subunit alpha 2 ...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ap2a2	0.000e+0	63.12	adaptor-related protein complex 2, alpha 2 subunit...	[more]
Ap2a1	0.000e+0	62.20	adaptor-related protein complex 2, alpha 1 subunit...	[more]
Ap2a1	0.000e+0	62.20	adaptor-related protein complex 2, alpha 1 subunit...	[more]
Ap2a1	0.000e+0	60.85	adaptor-related protein complex 2, alpha 1 subunit...	[more]
Ap2a1	0.000e+0	60.85	adaptor-related protein complex 2, alpha 1 subunit...	[more]

BLAST of AP-2 complex subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P17427\|AP2A2_MOUSE	0.000e+0	63.12	AP-2 complex subunit alpha-2 OS=Mus musculus OX=10...	[more]
sp\|P18484\|AP2A2_RAT	0.000e+0	63.02	AP-2 complex subunit alpha-2 OS=Rattus norvegicus ...	[more]
sp\|Q0VCK5\|AP2A2_BOVIN	0.000e+0	62.37	AP-2 complex subunit alpha-2 OS=Bos taurus OX=9913...	[more]
sp\|Q29N38\|AP2A_DROPS	0.000e+0	63.50	AP-2 complex subunit alpha OS=Drosophila pseudoobs...	[more]
sp\|O94973\|AP2A2_HUMAN	0.000e+0	62.41	AP-2 complex subunit alpha-2 OS=Homo sapiens OX=96...	[more]

BLAST of AP-2 complex subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S8WI37	0.000e+0	67.52	AP-2 complex subunit alpha OS=Opisthorchis viverri...	[more]
A0A4S2L4V5	0.000e+0	67.62	AP-2 complex subunit alpha OS=Opisthorchis felineu...	[more]
A0A4S2LAF5	0.000e+0	65.80	AP-2 complex subunit alpha OS=Opisthorchis felineu...	[more]
A0A4Z2CS53	0.000e+0	67.57	AP-2 complex subunit alpha OS=Schistosoma japonicu...	[more]
A0A4E0RYB5	0.000e+0	66.39	AP-2 complex subunit alpha OS=Fasciola hepatica OX...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ap2a1	0.000e+0	64.15	adaptor related protein complex 2 subunit alpha 1 ...	[more]
ENSAMXT00000003083.2	0.000e+0	62.69	pep primary_assembly:Astyanax_mexicanus-2.0:5:1159...	[more]
ap1g1	4.369e-75	29.50	adaptor related protein complex 1 subunit gamma 1 ...	[more]
ap1g1	9.394e-75	29.50	adaptor related protein complex 1 subunit gamma 1 ...	[more]
ap1g2	2.256e-73	29.77	AP-1 complex subunit gamma-1 [Source:NCBI gene;Acc...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000002119.1	0.000e+0	60.40	pep scaffold:Pmarinus_7.0:GL476740:177496:198372:1...	[more]
ENSPMAT00000000025.1	0.000e+0	80.43	pep scaffold:Pmarinus_7.0:GL482217:474:17538:-1 ge...	[more]
ENSPMAT00000003410.1	2.770e-48	40.89	pep scaffold:Pmarinus_7.0:GL480964:25073:33111:1 g...	[more]
ap3d1	7.629e-32	24.20	adaptor related protein complex 3 subunit delta 1 ...	[more]
ENSPMAT00000007788.1	1.889e-27	39.34	pep scaffold:Pmarinus_7.0:GL482991:1901:4831:1 gen...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
APL3	4.382e-66	28.76	Alpha-adaptin; large subunit of the clathrin assoc...	[more]
APL4	1.679e-27	23.65	Gamma-adaptin; large subunit of the clathrin-assoc...	[more]
APL5	5.534e-20	21.27	Delta adaptin-like subunit of the clathrin associa...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49151	0.000e+0	62.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41985	2.124e-75	27.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49859	1.433e-39	23.21	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38269	1.202e-34	25.31	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36135	3.899e-12	21.36	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of AP-2 complex subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ap2a1	0.000e+0	62.62	adaptor related protein complex 2 subunit alpha 1 ...	[more]
ap2a1	0.000e+0	62.01	adaptor related protein complex 2 subunit alpha 1 ...	[more]
ap2a1	0.000e+0	62.13	adaptor related protein complex 2 subunit alpha 1 ...	[more]
ENSORLT00000022962.2	0.000e+0	61.19	AP-2 complex subunit alpha-2 [Source:NCBI gene;Acc...	[more]
ap1g1	8.971e-75	29.67	adaptor related protein complex 1 subunit gamma 1 ...	[more]

BLAST of AP-2 complex subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000036030.1	0.000e+0	100.00	SMESG000036030.1	[more]
SMESG000031293.1	2.232e-64	26.54	SMESG000031293.1	[more]
SMESG000074044.1	5.828e-36	24.50	SMESG000074044.1	[more]
SMESG000074044.1	2.908e-34	24.21	SMESG000074044.1	[more]
SMESG000029126.1	2.155e-9	21.23	SMESG000029126.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30017036 ID=SMED30017036|Name=AP-2 complex subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=2958bp
CTATATAAATCTTATATGATTTTGAATAATGCCAACTGTTAAAGGAGATT
CAATGAGAGGCTTAGCAGTGTTCATATCTGATATCCGAAATTGTAAAAGT
AAAGAAGCTGAAATAAAAAGAATAAACAGGGAATTAGCAAATATTCGATC
AAAATTTAAAGGAGATAAAACATTAGATGGATATCAAAAGAAAAAATACG
TTTGCAAATTATTATTCATTTTCTTGTTGGGACATGATATAGACTTTGGC
CATTCGGAAGCTGTAAATTTACTCTGTTCAAATAAATATACTGAAAAACA
AATTGGATATCTTTTTATATCTGTACTAATCAACGAGTCACATAATTTAA
TGAATTTAGTCGTACAAAGATTAAAAGATGATTTAAGCAGTAGAAATCCC
GTTTTCGTTACTCTAGCCTTACAATGTATTGCTAATATTGGAACGAGAGA
AATGACGGAAAATTTTGCTAAAGAAATTCCTCGACTTCTTGTATCTGGAG
ATACTATTGATTCAGTTAAACAGAGTGCGGCTTTATGTCTATTAAAATTA
ATCAGAGCAGCTCCTGATTTAGTTCACTTCGATGATTGGACATCTCGTGT
TATACACTTACTTAATGACCAACACATGGGTGTCGTTACCGCCGCAGTAA
GCTTAATCGAAAGCCTCGTTAAGCGATCACCTGAAGAATACAAAGCATGT
GTATCACTAGCAGTTTCTCGATTGAGCAGAATAGTCACTTCATCCTACAC
TGATCTTCAAGACTATACTTATTACTTTGTACCTGCTCCATGGCTATCCG
TGAAACTGTTGAGGCTGTTGCAAAACTATCCCCCACCAGACGATGCACCT
GTGAGAAGCCGTTTAACTGAATGCCTTGAAAGCATACTAAGTAAAGCCCA
AGAGCCACCAAAATCGAAAAAGGTCCAACATTCAAATGCCAAAAATGCTG
TTTTATTCGAAGCTATTAATTTAATAATCCACATGGATTGTGATCCGAAT
CTCTTGATACGGGCATGTAATCAGCTCGGTCAATTTCTGTCGCACAGGGA
AACCAATTTACGCTACCTTGCACTGGAATCAATGTGCTTATTGGCTACTA
GCGAATTCAGTCATGAGGCAGTTAAAAAGCACCAAGAAACGGTTATTTCT
GCACTTAAGAGTGAACGAGATGTTTCAGTAAGACAACGAGCTGTGGACTT
GCTTTATGCAATGTGTGATAGGAATAATGCAGAGGAAATCGTAGGGGAAA
TGTTGTCCTATCTAGAGTCTGCTGATTATTCTATACGAGAAGAAATGGTT
TTAAAAGTGGCAATATTATCAGAAAAATACGCAACCGATTACAGCTGGTA
TGTTGATACTATTCTAAATTTGATTCGGGTTGCTGGCGACTATGTGAGTG
AAGAAGTTTGGCATAGAGTCATTCAGATTGTGATCAATAGAAGCGATGTT
CAGGGATATTCTGCCAAAACAGTGTTTGAAGCCCTACAGGCTCCAGCATG
CCATGAAAATATGGTCAAAGTTGGTGGCTATATTCTCGGCGAGTTTGGAA
ATTTAATTGCTGGAGATCCTAGATCCAGTCCTCAAATACAATTTCAAATT
CTCCATGCAAAATACCATTTATGCACACCAACAACTAGACAGTTACTGCT
TTCTACATATGTTAAGTTTATTAATCTATTTCCTGAAATCAAAGAAGAAA
TACAAGATATTTTAAAAAATGATTCTAATCTGCGAAATGCAGACGTAGAA
ATCCAGCAAAGAACAATAGAATATTTAACTTTATCTAAAATTGCCACAGA
TGATGTTATGGCGACTGTACTTGAAGAGATGCCTTCATTTACAGAAAGAG
AATCTAGTATATTAGCAAAATTAAAACAAAAAAAACCGGCGGCACTAGAA
GGCCAAGAATTGATTGCTCCTAGACAGCATCCAACTGCTAAAATATCTAA
AAATTCACTTGATACTCAAAATGATAGCCCAGCTACTAAAGAAGAACCCG
CTATACAAGAAGTTGATCTATTAGGGGGGCTGTTTTCTTATTCTCAACCA
AACCAAACTAATTCCAAATCAACATCTCAACCAACTTCAGATCTACTCCT
TGATATTTTAGGAAATGGATTCGATTCAGATATAAATGAAAATAAATCTT
CAACTAATCCAATTACTTTGGAACAATCCGAGTCCGATGAAAACTATTTA
AAATTACTTTGGAAATCAAGTGGAATTCTCTTTGAAAATGATAAAATACA
AATCGGAATCAAGTCGGAATTTCGAGGAAATATGGGTCGATTGGGCATTT
TCTATGGGAATAAGAGTTTGAAGCAAATGACAGATTTCGGAACGGAATTA
TGCAATTCTCCTCCAACAACGATTTTGAAATTGGATTTGAATCCAATCAA
ATCCGATATAGCTTCCGGGGATCAAGAACAGCAGCGCCTCAACATCGAAT
GTTTCCAGGCGTTTGATCAAACGATTTCACTGAAAGTTTTTTTCAACATT
GAAAAGCAATCCTATAAAATAATGCTGAACCTACCGATAACGATCAATAA
ATTTGTGGAATCAGCAGTTATGGATCAGAATACGTTTTTCCAAAGGTGGA
AAATTCTTTGTCAGCCCGGTCAAGAATGCCAAAGTGTTGTTAAATCATTG
AAATGCCCGATGGAGCTCTCAGTGTTGCAAACAAGATTAGAAGGTCTTAA
TTTAAGTGTCCTATCCAATATCGATCCTGTTGCCAGTAATTTTGTTGCTT
CTGGAATAGTTAATATGTCATCGCAAAAAGTTGGAGTTCTATTGCGACTG
GAACCAAATATGGCTACAAAGATATATCGGCTGACTGTCCGTAGCACGAA
GGATATAGTATCACGGAAAATGTTCAATATTATTGAATCGTTATTATAAA
TATTATTATTATTATTTATTATAATAATAATTATTTATTATTATTATTAT
TATTTATT

protein sequence of SMED30017036-orf-1

>SMED30017036-orf-1 ID=SMED30017036-orf-1|Name=SMED30017036-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=957bp
MPTVKGDSMRGLAVFISDIRNCKSKEAEIKRINRELANIRSKFKGDKTLD
GYQKKKYVCKLLFIFLLGHDIDFGHSEAVNLLCSNKYTEKQIGYLFISVL
INESHNLMNLVVQRLKDDLSSRNPVFVTLALQCIANIGTREMTENFAKEI
PRLLVSGDTIDSVKQSAALCLLKLIRAAPDLVHFDDWTSRVIHLLNDQHM
GVVTAAVSLIESLVKRSPEEYKACVSLAVSRLSRIVTSSYTDLQDYTYYF
VPAPWLSVKLLRLLQNYPPPDDAPVRSRLTECLESILSKAQEPPKSKKVQ
HSNAKNAVLFEAINLIIHMDCDPNLLIRACNQLGQFLSHRETNLRYLALE
SMCLLATSEFSHEAVKKHQETVISALKSERDVSVRQRAVDLLYAMCDRNN
AEEIVGEMLSYLESADYSIREEMVLKVAILSEKYATDYSWYVDTILNLIR
VAGDYVSEEVWHRVIQIVINRSDVQGYSAKTVFEALQAPACHENMVKVGG
YILGEFGNLIAGDPRSSPQIQFQILHAKYHLCTPTTRQLLLSTYVKFINL
FPEIKEEIQDILKNDSNLRNADVEIQQRTIEYLTLSKIATDDVMATVLEE
MPSFTERESSILAKLKQKKPAALEGQELIAPRQHPTAKISKNSLDTQNDS
PATKEEPAIQEVDLLGGLFSYSQPNQTNSKSTSQPTSDLLLDILGNGFDS
DINENKSSTNPITLEQSESDENYLKLLWKSSGILFENDKIQIGIKSEFRG
NMGRLGIFYGNKSLKQMTDFGTELCNSPPTTILKLDLNPIKSDIASGDQE
QQRLNIECFQAFDQTISLKVFFNIEKQSYKIMLNLPITINKFVESAVMDQ
NTFFQRWKILCQPGQECQSVVKSLKCPMELSVLQTRLEGLNLSVLSNIDP
VASNFVASGIVNMSSQKVGVLLRLEPNMATKIYRLTVRSTKDIVSRKMFN
IIESLL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005905	clathrin-coated pit
GO:0030122	AP-2 adaptor complex
GO:0030131	clathrin adaptor complex
GO:0016020	membrane
GO:0030117	membrane coat
GO:0005737	cytoplasm

Vocabulary: **biological process**
Term	Definition
GO:0006897	endocytosis
GO:0072583	clathrin-dependent endocytosis
GO:0006886	intracellular protein transport
GO:0016192	vesicle-mediated transport
GO:0015031	protein transport
GO:0006810	transport

Vocabulary: **molecular function**
Term	Definition
GO:0035615	clathrin adaptor activity
GO:0008565	protein transporter activity
GO:0005488	binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000099	neuron

Vocabulary: **INTERPRO**
Term	Definition
IPR012295	TBP_dom_sf
IPR008152	Clathrin_a/b/g-adaptin_app_Ig
IPR013038	Clathrin_a-adaptin_app_Ig-like
IPR017104	AP2_complex_asu
IPR002553	Clathrin/coatomer_adapt-like_N
IPR003164	Clathrin_a-adaptin_app_sub_C
IPR011989	ARM-like
IPR015873	Clathrin_a/coatomer_app_sub_C
IPR013041	Clathrin_app_Ig-like_sf
IPR009028	Coatomer/calthrin_app_sub_C
IPR016024	ARM-type_fold

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 22..42
None	No IPR available	GENE3D	G3DSA:2.60.40.1230		coord: 711..842 e-value: 1.0E-36 score: 127.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 636..654
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 625..655
None	No IPR available	PANTHER	PTHR22780	ADAPTIN, ALPHA/GAMMA/EPSILON	coord: 4..952
None	No IPR available	PANTHER	PTHR22780:SF33	AP-2 COMPLEX SUBUNIT ALPHA-1	coord: 4..952
IPR008152	Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain	SMART	SM00809	alpha_adaptinc2	coord: 724..836 e-value: 2.3E-13 score: 60.4
IPR008152	Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain	PFAM	PF02883	Alpha_adaptinC2	coord: 731..828 e-value: 2.7E-14 score: 53.4
IPR003164	Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain	PFAM	PF02296	Alpha_adaptin_C	coord: 842..950 e-value: 4.7E-30 score: 104.1
IPR011989	Armadillo-like helical	GENE3D	G3DSA:1.25.10.10		coord: 3..620 e-value: 1.6E-222 score: 742.3
IPR017104	Adaptor protein complex AP-2, alpha subunit	PIRSF	PIRSF037091	AP2_alpha	coord: 3..956 e-value: 0.0 score: 1148.8
IPR002553	Clathrin/coatomer adaptor, adaptin-like, N-terminal	PFAM	PF01602	Adaptin_N	coord: 30..587 e-value: 5.4E-143 score: 477.3
IPR012295	TBP domain superfamily	GENE3D	G3DSA:3.30.310.10		coord: 843..955 e-value: 2.5E-33 score: 116.2
IPR016024	Armadillo-type fold	SUPERFAMILY	SSF48371	ARM repeat	coord: 9..590
IPR013041	Clathrin adaptor, appendage, Ig-like subdomain superfamily	SUPERFAMILY	SSF49348	Clathrin adaptor appendage domain	coord: 719..841
IPR009028	Coatomer/calthrin adaptor appendage, C-terminal subdomain	SUPERFAMILY	SSF55711	Subdomain of clathrin and coatomer appendage domain	coord: 842..955