SMED30017008

Overview


Name	SMED30017008
Smed ID	SMED30017008
Length (bp)	580

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30017008

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
neoblast	SMED30017008	AY067447	smed_ncbi_20200123	PMID:21566185 Wagner et al., 2011
neoblast	SMED30017008	H.39.11e	smed_ncbi_20200123	PMID:21566185 Wagner et al., 2011
Category 1 cell	SMED30017008	H.39.11e	smed_ncbi_20200123	PMID:18786419 Eisenhoffer et al., 2008
Category 1 cell	SMED30017008	H.39.11e	smed_ncbi_20200123	PMID:18786419 Eisenhoffer et al., 2008

Note: Hover over icons to view figure legend

Alignments

SMED30017008 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.036403:1436..2000 -	2095
v31.036428:1268..1831 -	2078

Homology

[Close]

BLAST of SMED30017008 vs. Ensembl Human
Match: RRM2B (ribonucleotide reductase regulatory TP53 inducible subunit M2B [Source:HGNC Symbol;Acc:HGNC:17296])

HSP 1 Score: 47.7506 bits (112), Expect = 1.047e-6
Identity = 26/57 (45.61%), Postives = 31/57 (54.39%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R L   G  K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:   62 LIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSE 118

[Close]

BLAST of SMED30017008 vs. Ensembl Human
Match: RRM2 (ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452])

HSP 1 Score: 48.9062 bits (115), Expect = 1.515e-6
Identity = 26/57 (45.61%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R +   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  312 LIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGE 368

[Close]

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R +   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  312 LIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGE 368

[Close]

BLAST of SMED30017008 vs. Ensembl Human
Match: RRM2 (ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452])

HSP 1 Score: 48.521 bits (114), Expect = 2.038e-6
Identity = 26/57 (45.61%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R +   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  372 LIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGE 428

[Close]

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R +   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  372 LIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGE 428

[Close]

BLAST of SMED30017008 vs. Ensembl Celegans
Match: rnr-2 (Ribonucleoside-diphosphate reductase small chain [Source:UniProtKB/Swiss-Prot;Acc:P42170])

HSP 1 Score: 59.6918 bits (143), Expect = 1.147e-10
Identity = 33/73 (45.21%), Postives = 39/73 (53.42%), Query Frame = -3

Query:  333 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENS---MSSGEGQPQFD 542
            + GMN        E VA   L   GCDK + +KNP DFM+ I IDGKTNFF KR  E     +   E + QFD
Sbjct:  304 MIGMNCRLMSQYIEFVADHLLVELGCDKLYKSKNPFDFMENISIDGKTNFFEKRVSEYQRPGVMVNEAERQFD 376

[Close]

BLAST of SMED30017008 vs. Ensembl Celegans
Match: F19G12.2 (pep chromosome:WBcel235:X:1427774:1430871:1 gene:WBGene00017610.1 transcript:F19G12.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F19G12.2)

HSP 1 Score: 51.9878 bits (123), Expect = 6.377e-8
Identity = 33/73 (45.21%), Postives = 37/73 (50.68%), Query Frame = -3

Query:  333 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE---NSMSSGEGQPQFD 542
            L GMN        E VA   L   G  K +NTKNP DFM+ I I+GKTNFF KR  E     M   E +  FD
Sbjct:  591 LIGMNQHMMCKYVEFVADLLLEELGYSKRYNTKNPFDFMENISIEGKTNFFEKRVSEYQRPEMMVDESEKVFD 663

[Close]

BLAST of SMED30017008 vs. Ensembl Fly
Match: RnrS (gene:FBgn0011704 transcript:FBtr0088046)

HSP 1 Score: 55.8398 bits (133), Expect = 3.063e-9
Identity = 29/57 (50.88%), Postives = 35/57 (61.40%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   G  K +NTKNP +FM+ I +DGKTNFF K+ GE
Sbjct:  316 LIGMNCDLMSQYIEFVADRLLVELGVGKIYNTKNPFNFMEMISLDGKTNFFEKKVGE 372

[Close]

BLAST of SMED30017008 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase M2 polypeptide [Source:NCBI gene;Acc:30733])

HSP 1 Score: 53.5286 bits (127), Expect = 2.550e-8
Identity = 28/57 (49.12%), Postives = 34/57 (59.65%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   G DK +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  280 LIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGE 336

[Close]

BLAST of SMED30017008 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:100330864])

HSP 1 Score: 53.5286 bits (127), Expect = 2.550e-8
Identity = 28/57 (49.12%), Postives = 34/57 (59.65%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   G DK +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  280 LIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGE 336

[Close]

BLAST of SMED30017008 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase M2 polypeptide [Source:NCBI gene;Acc:30733])

HSP 1 Score: 53.5286 bits (127), Expect = 2.593e-8
Identity = 28/57 (49.12%), Postives = 34/57 (59.65%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   G DK +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  257 LIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGE 313

[Close]

BLAST of SMED30017008 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:100330864])

HSP 1 Score: 53.5286 bits (127), Expect = 2.593e-8
Identity = 28/57 (49.12%), Postives = 34/57 (59.65%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   G DK +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  257 LIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGE 313

[Close]

BLAST of SMED30017008 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase M2 polypeptide [Source:NCBI gene;Acc:30733])

HSP 1 Score: 53.5286 bits (127), Expect = 2.779e-8
Identity = 28/57 (49.12%), Postives = 34/57 (59.65%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   G DK +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  309 LIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGE 365

[Close]

BLAST of SMED30017008 vs. Ensembl Xenopus
Match: rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:NCBI gene;Acc:100144925])

HSP 1 Score: 51.9878 bits (123), Expect = 1.184e-7
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R L   GC K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  206 LIGMNCTLMKTYIEFVADRLLVELGCSKAFKAENPFDFMENISLEGKTNFFEKRVSE 262

[Close]

BLAST of SMED30017008 vs. Ensembl Xenopus
Match: rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:NCBI gene;Acc:100144925])

HSP 1 Score: 51.6026 bits (122), Expect = 1.509e-7
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R L   GC K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  260 LIGMNCTLMKTYIEFVADRLLVELGCSKAFKAENPFDFMENISLEGKTNFFEKRVSE 316

[Close]

BLAST of SMED30017008 vs. Ensembl Xenopus
Match: rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:NCBI gene;Acc:100144925])

HSP 1 Score: 51.6026 bits (122), Expect = 1.733e-7
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R L   GC K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  269 LIGMNCTLMKTYIEFVADRLLVELGCSKAFKAENPFDFMENISLEGKTNFFEKRVSE 325

[Close]

BLAST of SMED30017008 vs. Ensembl Xenopus
Match: rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:NCBI gene;Acc:100144925])

HSP 1 Score: 51.2174 bits (121), Expect = 1.993e-7
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R L   GC K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  274 LIGMNCTLMKTYIEFVADRLLVELGCSKAFKAENPFDFMENISLEGKTNFFEKRVSE 330

[Close]

BLAST of SMED30017008 vs. Ensembl Xenopus
Match: rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:NCBI gene;Acc:100144925])

HSP 1 Score: 51.2174 bits (121), Expect = 2.128e-7
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R L   GC K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  339 LIGMNCTLMKTYIEFVADRLLVELGCSKAFKAENPFDFMENISLEGKTNFFEKRVSE 395

[Close]

BLAST of SMED30017008 vs. Ensembl Mouse
Match: Rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:MGI Symbol;Acc:MGI:2155865])

HSP 1 Score: 50.8322 bits (120), Expect = 5.568e-8
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R LG  G  K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:   62 LIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSE 118

[Close]

BLAST of SMED30017008 vs. Ensembl Mouse
Match: Rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:MGI Symbol;Acc:MGI:2155865])

HSP 1 Score: 50.8322 bits (120), Expect = 2.099e-7
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R LG  G  K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  222 LIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSE 278

[Close]

BLAST of SMED30017008 vs. Ensembl Mouse
Match: Rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:MGI Symbol;Acc:MGI:2155865])

HSP 1 Score: 50.8322 bits (120), Expect = 2.265e-7
Identity = 27/57 (47.37%), Postives = 32/57 (56.14%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R LG  G  K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  274 LIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSE 330

[Close]

BLAST of SMED30017008 vs. Ensembl Mouse
Match: Rrm2 (ribonucleotide reductase M2 [Source:MGI Symbol;Acc:MGI:98181])

HSP 1 Score: 50.0618 bits (118), Expect = 5.194e-7
Identity = 26/57 (45.61%), Postives = 33/57 (57.89%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN        E VA R +   G +K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  313 LIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGE 369

[Close]

BLAST of SMED30017008 vs. Ensembl Mouse
Match: Rrm2 (ribonucleotide reductase M2 [Source:MGI Symbol;Acc:MGI:98181])

HSP 1 Score: 46.2098 bits (108), Expect = 7.568e-6
Identity = 22/44 (50.00%), Postives = 29/44 (65.91%), Query Frame = -3

Query:  372 EXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 503
            E VA R +   G +K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  179 EFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGE 222

[Close]

BLAST of SMED30017008 vs. UniProt/SwissProt
Match: sp|P0DKH3|RI2BL_ARATH (Ribonucleoside-diphosphate reductase small chain B OS=Arabidopsis thaliana OX=3702 GN=RNR2B PE=2 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 5.423e-10
Identity = 35/77 (45.45%), Postives = 41/77 (53.25%), Query Frame = -3

Query:  324 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE----NSMSSGEGQPQFDDVH 542
            L GMN E      E VA R L   GC K +   NP D+M+ I + GKTNFF KR GE    + MSS  G   F+D H
Sbjct:  249 LVGMNRELMSQYIEFVADRLLAALGCAKVYGVSNPFDWMELISLQGKTNFFEKRVGEYQKASIMSSVHGNAAFNDDH 325

[Close]

BLAST of SMED30017008 vs. UniProt/SwissProt
Match: sp|P42170|RIR2_CAEEL (Ribonucleoside-diphosphate reductase small chain OS=Caenorhabditis elegans OX=6239 GN=rnr-2 PE=3 SV=1)

HSP 1 Score: 59.6918 bits (143), Expect = 1.459e-9
Identity = 33/73 (45.21%), Postives = 39/73 (53.42%), Query Frame = -3

Query:  333 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENS---MSSGEGQPQFD 542
            + GMN        E VA   L   GCDK + +KNP DFM+ I IDGKTNFF KR  E     +   E + QFD
Sbjct:  304 MIGMNCRLMSQYIEFVADHLLVELGCDKLYKSKNPFDFMENISIDGKTNFFEKRVSEYQRPGVMVNEAERQFD 376

[Close]

BLAST of SMED30017008 vs. UniProt/SwissProt
Match: sp|P07201|RIR2_SPISO (Ribonucleoside-diphosphate reductase small chain OS=Spisula solidissima OX=6584 PE=2 SV=2)

HSP 1 Score: 57.7658 bits (138), Expect = 7.819e-9
Identity = 31/61 (50.82%), Postives = 37/61 (60.66%), Query Frame = -3

Query:  372 CRFXLXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 554
            CR  L GMN +      E VA R L    CDK +N +NP DFM+ I ++GKTNFF KR GE
Sbjct:  302 CR--LIGMNCDLMRQYIEFVADRLLLELKCDKLYNKENPFDFMEHISLEGKTNFFEKRVGE 360

[Close]

BLAST of SMED30017008 vs. UniProt/SwissProt
Match: sp|Q9DHU2|RIR2_YLDV (Ribonucleoside-diphosphate reductase small chain OS=Yaba-like disease virus OX=132475 GN=20L PE=3 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 8.406e-9
Identity = 29/57 (50.88%), Postives = 36/57 (63.16%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   GCDK++ +KNP DFM+ I ++GKTNFF KR  E
Sbjct:  248 LIGMNCDLMKQYIEFVADRLLLELGCDKYYCSKNPFDFMENISLEGKTNFFEKRVSE 304

[Close]

BLAST of SMED30017008 vs. UniProt/SwissProt
Match: sp|O15910|RIR2_TRYBB (Ribonucleoside-diphosphate reductase small chain OS=Trypanosoma brucei brucei OX=5702 GN=RNR2 PE=2 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 1.040e-8
Identity = 29/57 (50.88%), Postives = 35/57 (61.40%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R L   G D+ +N+KNP DFMD I + GKTNFF K+ GE
Sbjct:  259 LIGMNSQLMTQYIEFVADRLLVSLGYDRHYNSKNPFDFMDMISLQGKTNFFEKKVGE 315

[Close]

BLAST of SMED30017008 vs. TrEMBL
Match: I1ZI90 (Ribonucleoside diphosphate reductase subunit M2-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 8.853e-20
Identity = 48/73 (65.75%), Postives = 52/73 (71.23%), Query Frame = -3

Query:  324 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMSSGEGQPQFDDVH 542
            L GMN E      E VA R L   GCDKFWNT+NPLDFMD ICIDGKTNFF KR GE SMSS E + +FDDV+
Sbjct:  244 LIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 316

HSP 2 Score: 56.6102 bits (135), Expect = 4.545e-6
Identity = 26/41 (63.41%), Postives = 34/41 (82.93%), Query Frame = -3

Query:  120 FVEKICLDGETNCF*RRVSEYSLSSGEGKPQFDDVHFDIDF 242
            F++ IC+DG+TN F +RV EYS+SS E K +FDDV+FDIDF
Sbjct:  281 FMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVNFDIDF 321

[Close]

BLAST of SMED30017008 vs. TrEMBL
Match: A0A1J5L025 (Ribonucleoside-diphosphate reductase OS=Crocinitomix sp. MedPE-SWsnd OX=1860084 GN=BM555_06130 PE=4 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 5.720e-10
Identity = 37/70 (52.86%), Postives = 41/70 (58.57%), Query Frame = -3

Query:  345 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENS----MSSGEGQ 542
            L GMN E      E VA R LG  GC+K +NT NP DFMD I I GKTNFF KR  E      ++SGE Q
Sbjct:  248 LIGMNAELMQQYIEFVADRLLGELGCEKVYNTTNPFDFMDMISIQGKTNFFEKRVAEYQKAGVLNSGENQ 317

[Close]

BLAST of SMED30017008 vs. TrEMBL
Match: E3M8C7 (Uncharacterized protein OS=Caenorhabditis remanei OX=31234 GN=CRE_13354 PE=4 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 8.469e-10
Identity = 35/73 (47.95%), Postives = 40/73 (54.79%), Query Frame = -3

Query:  333 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENS---MSSGEGQPQFD 542
            + GMN        E VA   L   GCDK +N KNP DFM+ I IDGKTNFF KR  E     + S E + QFD
Sbjct:   70 MIGMNCRLMSQYIEFVADHLLAELGCDKLYNVKNPFDFMENISIDGKTNFFEKRVSEYQRPGVMSTETERQFD 142

[Close]

BLAST of SMED30017008 vs. TrEMBL
Match: A0A1I7BDU3 (Ribonucleoside-diphosphate reductase beta chain OS=Lishizhenia tianjinensis OX=477690 GN=SAMN05216474_2715 PE=4 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 2.858e-9
Identity = 37/71 (52.11%), Postives = 39/71 (54.93%), Query Frame = -3

Query:  342 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENS----MSSGEGQP 542
            L GMN E      E VA R L   GC+K +N  NP DFMD I I GKTNFF KR GE      MS  EGQ 
Sbjct:  247 LIGMNSELMSQYIEFVADRLLAELGCEKVFNVSNPFDFMDMISIQGKTNFFEKRVGEYQKAGVMSGNEGQS 317

[Close]

BLAST of SMED30017008 vs. TrEMBL
Match: A0A261C734 (Uncharacterized protein (Fragment) OS=Caenorhabditis latens OX=1503980 GN=FL83_07231 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 4.169e-9
Identity = 34/73 (46.58%), Postives = 39/73 (53.42%), Query Frame = -3

Query:  333 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENS---MSSGEGQPQFD 542
            + GMN        E V    L   GCDK +N KNP DFM+ I IDGKTNFF KR  E     + S E + QFD
Sbjct:   61 MIGMNCRLMSQYIEIVTDHLLAELGCDKVYNVKNPFDFMENISIDGKTNFFEKRVSEYQRPGVMSTETERQFD 133

[Close]

BLAST of SMED30017008 vs. Ensembl Cavefish
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:103024314])

HSP 1 Score: 50.8322 bits (120), Expect = 1.808e-7
Identity = 26/57 (45.61%), Postives = 33/57 (57.89%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R +   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  309 LIGMNCDLMKQYIEFVADRLMLELGFSKIYKVENPFDFMENISLEGKTNFFEKRVGE 365

[Close]

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R +   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  309 LIGMNCDLMKQYIEFVADRLMLELGFSKIYKVENPFDFMENISLEGKTNFFEKRVGE 365

[Close]

BLAST of SMED30017008 vs. Ensembl Cavefish
Match: rrm2b (ribonucleoside-diphosphate reductase subunit M2 B-like [Source:NCBI gene;Acc:103028967])

HSP 1 Score: 46.595 bits (109), Expect = 4.595e-6
Identity = 24/57 (42.11%), Postives = 30/57 (52.63%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L G+N        E VA R L      K +  +NP DFM+ I ++GKTNFF KR  E
Sbjct:  272 LIGINCSLMKQYIEFVADRLLTDLAMPKVYKAENPFDFMESISLEGKTNFFEKRVAE 328

[Close]

BLAST of SMED30017008 vs. Ensembl Sea Lamprey
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:100330864])

HSP 1 Score: 54.299 bits (129), Expect = 2.285e-9
Identity = 27/57 (47.37%), Postives = 34/57 (59.65%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN +      E VA R LG  GC K +  +NP DFM+ I ++GKTNFF K+  E
Sbjct:  261 LIGMNCDLMKQYIEFVADRLLGELGCAKVYRAENPFDFMENISLEGKTNFFEKKVAE 317

[Close]

BLAST of SMED30017008 vs. Ensembl Yeast
Match: RNR2 (Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits; RNR2 has a paralog, RNR4, that arose from the whole genome duplication [Source:SGD;Acc:S000003563])

HSP 1 Score: 49.2914 bits (116), Expect = 8.449e-8
Identity = 25/54 (46.30%), Postives = 31/54 (57.41%), Query Frame = -3

Query:  381 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KR 542
            L GMN +      E VA R L   G  K++  +NP DFM+ I + GKTNFF KR
Sbjct:  319 LLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKR 372

[Close]

BLAST of SMED30017008 vs. Ensembl Nematostella
Match: EDO42117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2C2])

HSP 1 Score: 55.0694 bits (131), Expect = 2.072e-9
Identity = 29/61 (47.54%), Postives = 34/61 (55.74%), Query Frame = -3

Query:  360 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMS 542
            L GMN        E VA R L    C K +N +NP DFM+ I ++GKTNFF KR GE   S
Sbjct:  264 LIGMNCALMRQYIEFVADRLLVALNCQKVYNVENPFDFMENISLEGKTNFFEKRVGEYQKS 324

[Close]

BLAST of SMED30017008 vs. Ensembl Nematostella
Match: EDO42116 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2C0])

HSP 1 Score: 55.0694 bits (131), Expect = 2.892e-9
Identity = 29/61 (47.54%), Postives = 34/61 (55.74%), Query Frame = -3

Query:  360 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMS 542
            L GMN        E VA R L    C K +N +NP DFM+ I ++GKTNFF KR GE   S
Sbjct:  307 LIGMNCALMRQYIEFVADRLLVALNCQKVYNAENPFDFMENISLEGKTNFFEKRVGEYQKS 367

[Close]

BLAST of SMED30017008 vs. Ensembl Nematostella
Match: EDO42087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2C1])

HSP 1 Score: 54.299 bits (129), Expect = 4.820e-9
Identity = 28/61 (45.90%), Postives = 34/61 (55.74%), Query Frame = -3

Query:  360 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMS 542
            L GMN        E VA R L    C K +N +NP DFM+ I ++GKTNF+ KR GE   S
Sbjct:  307 LIGMNCALMRQYIEFVADRLLVALNCQKVYNVENPFDFMENISLEGKTNFYEKRVGEYQKS 367

[Close]

BLAST of SMED30017008 vs. Ensembl Medaka
Match: ENSORLT00000040809.1 (ribonucleoside-diphosphate reductase subunit M2 [Source:NCBI gene;Acc:101158912])

HSP 1 Score: 52.7582 bits (125), Expect = 8.610e-9
Identity = 28/57 (49.12%), Postives = 33/57 (57.89%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN E      E VA R L   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:   62 LIGMNCELMKQYIEFVADRLLLELGFSKIYRAENPFDFMENISLEGKTNFFEKRVGE 118

[Close]

BLAST of SMED30017008 vs. Ensembl Medaka
Match: ENSORLT00000025443.2 (ribonucleoside-diphosphate reductase subunit M2 [Source:NCBI gene;Acc:101158912])

HSP 1 Score: 53.1434 bits (126), Expect = 2.519e-8
Identity = 28/57 (49.12%), Postives = 33/57 (57.89%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN E      E VA R L   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  220 LIGMNCELMKQYIEFVADRLLLELGFSKIYRAENPFDFMENISLEGKTNFFEKRVGE 276

[Close]

BLAST of SMED30017008 vs. Ensembl Medaka
Match: RRM2 (ribonucleoside-diphosphate reductase subunit M2-like [Source:NCBI gene;Acc:101166844])

HSP 1 Score: 53.1434 bits (126), Expect = 2.778e-8
Identity = 28/57 (49.12%), Postives = 33/57 (57.89%), Query Frame = -3

Query:  372 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGE 542
            L GMN E      E VA R L   G  K +  +NP DFM+ I ++GKTNFF KR GE
Sbjct:  302 LIGMNCELMKQYIEFVADRLLLELGFSKIYRAENPFDFMENISLEGKTNFFEKRVGE 358

[Close]

BLAST of SMED30017008 vs. Planmine SMEST
Match: SMESG000044184.1 (SMESG000044184.1)

HSP 1 Score: 93.9745 bits (232), Expect = 2.766e-24
Identity = 48/73 (65.75%), Postives = 52/73 (71.23%), Query Frame = -3

Query:  324 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMSSGEGQPQFDDVH 542
            L GMN E      E VA R L   GCDKFWNT+NPLDFMD ICIDGKTNFF KR GE SMSS E + +FDDV+
Sbjct:   88 LIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRCGEYSMSSVEDKHKFDDVN 160

HSP 2 Score: 53.5286 bits (127), Expect = 4.726e-9
Identity = 25/41 (60.98%), Postives = 33/41 (80.49%), Query Frame = -3

Query:  120 FVEKICLDGETNCF*RRVSEYSLSSGEGKPQFDDVHFDIDF 242
            F++ IC+DG+TN F +R  EYS+SS E K +FDDV+FDIDF
Sbjct:  125 FMDNICIDGKTNFFEKRCGEYSMSSVEDKHKFDDVNFDIDF 165

[Close]

BLAST of SMED30017008 vs. Planmine SMEST
Match: SMESG000079368.1 (SMESG000079368.1)

HSP 1 Score: 94.7449 bits (234), Expect = 2.462e-23
Identity = 48/73 (65.75%), Postives = 52/73 (71.23%), Query Frame = -3

Query:  324 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMSSGEGQPQFDDVH 542
            L GMN E      E VA R L   GCDKFWNT+NPLDFMD ICIDGKTNFF KR GE SMSS E + +FDDV+
Sbjct:  244 LIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 316

HSP 2 Score: 56.6102 bits (135), Expect = 1.264e-9
Identity = 26/41 (63.41%), Postives = 34/41 (82.93%), Query Frame = -3

Query:  120 FVEKICLDGETNCF*RRVSEYSLSSGEGKPQFDDVHFDIDF 242
            F++ IC+DG+TN F +RV EYS+SS E K +FDDV+FDIDF
Sbjct:  281 FMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVNFDIDF 321

[Close]

BLAST of SMED30017008 vs. Planmine SMEST
Match: SMESG000044188.1 (SMESG000044188.1)

HSP 1 Score: 94.7449 bits (234), Expect = 2.462e-23
Identity = 48/73 (65.75%), Postives = 52/73 (71.23%), Query Frame = -3

Query:  324 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMSSGEGQPQFDDVH 542
            L GMN E      E VA R L   GCDKFWNT+NPLDFMD ICIDGKTNFF KR GE SMSS E + +FDDV+
Sbjct:  244 LIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 316

HSP 2 Score: 56.6102 bits (135), Expect = 1.264e-9
Identity = 26/41 (63.41%), Postives = 34/41 (82.93%), Query Frame = -3

Query:  120 FVEKICLDGETNCF*RRVSEYSLSSGEGKPQFDDVHFDIDF 242
            F++ IC+DG+TN F +RV EYS+SS E K +FDDV+FDIDF
Sbjct:  281 FMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVNFDIDF 321

[Close]

BLAST of SMED30017008 vs. Planmine SMEST
Match: SMESG000044184.1 (SMESG000044184.1)

HSP 1 Score: 92.4337 bits (228), Expect = 7.065e-23
Identity = 48/73 (65.75%), Postives = 52/73 (71.23%), Query Frame = -3

Query:  324 LXGMNPEXXXXDXEXVAXRXLG*XGCDKFWNTKNPLDFMDKICIDGKTNFF*KRGGENSMSSGEGQPQFDDVH 542
            L GMN E      E VA R L   GCDKFWNT+NPLDFMD ICIDGKTNFF KR GE SMSS E + +FDDV+
Sbjct:  190 LIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRCGEYSMSSVEDKHKFDDVN 262

HSP 2 Score: 53.5286 bits (127), Expect = 1.246e-8
Identity = 25/41 (60.98%), Postives = 33/41 (80.49%), Query Frame = -3

Query:  120 FVEKICLDGETNCF*RRVSEYSLSSGEGKPQFDDVHFDIDF 242
            F++ IC+DG+TN F +R  EYS+SS E K +FDDV+FDIDF
Sbjct:  227 FMDNICIDGKTNFFEKRCGEYSMSSVEDKHKFDDVNFDIDF 267

The following BLAST results are available for this feature:

BLAST of SMED30017008 vs. Ensembl Human
BLAST of SMED30017008 vs. Ensembl Celegans
BLAST of SMED30017008 vs. Ensembl Fly
BLAST of SMED30017008 vs. Ensembl Zebrafish
BLAST of SMED30017008 vs. Ensembl Xenopus
BLAST of SMED30017008 vs. Ensembl Mouse
BLAST of SMED30017008 vs. UniProt/SwissProt
BLAST of SMED30017008 vs. TrEMBL
BLAST of SMED30017008 vs. Ensembl Cavefish
BLAST of SMED30017008 vs. Ensembl Sea Lamprey
BLAST of SMED30017008 vs. Ensembl Yeast
BLAST of SMED30017008 vs. Ensembl Nematostella
BLAST of SMED30017008 vs. Ensembl Medaka
BLAST of SMED30017008 vs. Planmine SMEST

BLAST of SMED30017008 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RRM2B	1.047e-6	45.61	ribonucleotide reductase regulatory TP53 inducible...	[more]
RRM2	1.515e-6	45.61	ribonucleotide reductase regulatory subunit M2 [So...	[more]
RRM2	1.515e-6	45.61	ribonucleotide reductase regulatory subunit M2 [So...	[more]
RRM2	2.038e-6	45.61	ribonucleotide reductase regulatory subunit M2 [So...	[more]
RRM2	2.038e-6	45.61	ribonucleotide reductase regulatory subunit M2 [So...	[more]

BLAST of SMED30017008 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
rnr-2	1.147e-10	45.21	Ribonucleoside-diphosphate reductase small chain ...	[more]
F19G12.2	6.377e-8	45.21	pep chromosome:WBcel235:X:1427774:1430871:1 gene:W...	[more]

BLAST of SMED30017008 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
RnrS	3.063e-9	50.88	gene:FBgn0011704 transcript:FBtr0088046	[more]

BLAST of SMED30017008 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rrm2	2.550e-8	49.12	ribonucleotide reductase M2 polypeptide [Source:NC...	[more]
rrm2	2.550e-8	49.12	ribonucleotide reductase regulatory subunit M2 [So...	[more]
rrm2	2.593e-8	49.12	ribonucleotide reductase M2 polypeptide [Source:NC...	[more]
rrm2	2.593e-8	49.12	ribonucleotide reductase regulatory subunit M2 [So...	[more]
rrm2	2.779e-8	49.12	ribonucleotide reductase M2 polypeptide [Source:NC...	[more]

BLAST of SMED30017008 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rrm2b	1.184e-7	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]
rrm2b	1.509e-7	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]
rrm2b	1.733e-7	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]
rrm2b	1.993e-7	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]
rrm2b	2.128e-7	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]

BLAST of SMED30017008 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rrm2b	5.568e-8	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]
Rrm2b	2.099e-7	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]
Rrm2b	2.265e-7	47.37	ribonucleotide reductase M2 B (TP53 inducible) [So...	[more]
Rrm2	5.194e-7	45.61	ribonucleotide reductase M2 [Source:MGI Symbol;Acc...	[more]
Rrm2	7.568e-6	50.00	ribonucleotide reductase M2 [Source:MGI Symbol;Acc...	[more]

BLAST of SMED30017008 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0DKH3\|RI2BL_ARATH	5.423e-10	45.45	Ribonucleoside-diphosphate reductase small chain B...	[more]
sp\|P42170\|RIR2_CAEEL	1.459e-9	45.21	Ribonucleoside-diphosphate reductase small chain O...	[more]
sp\|P07201\|RIR2_SPISO	7.819e-9	50.82	Ribonucleoside-diphosphate reductase small chain O...	[more]
sp\|Q9DHU2\|RIR2_YLDV	8.406e-9	50.88	Ribonucleoside-diphosphate reductase small chain O...	[more]
sp\|O15910\|RIR2_TRYBB	1.040e-8	50.88	Ribonucleoside-diphosphate reductase small chain O...	[more]

BLAST of SMED30017008 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZI90	8.853e-20	65.75	Ribonucleoside diphosphate reductase subunit M2-2 ...	[more]
A0A1J5L025	5.720e-10	52.86	Ribonucleoside-diphosphate reductase OS=Crocinitom...	[more]
E3M8C7	8.469e-10	47.95	Uncharacterized protein OS=Caenorhabditis remanei ...	[more]
A0A1I7BDU3	2.858e-9	52.11	Ribonucleoside-diphosphate reductase beta chain OS...	[more]
A0A261C734	4.169e-9	46.58	Uncharacterized protein (Fragment) OS=Caenorhabdit...	[more]

BLAST of SMED30017008 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
rrm2	1.808e-7	45.61	ribonucleotide reductase regulatory subunit M2 [So...	[more]
rrm2	1.808e-7	45.61	ribonucleotide reductase regulatory subunit M2 [So...	[more]
rrm2b	4.595e-6	42.11	ribonucleoside-diphosphate reductase subunit M2 B-...	[more]

BLAST of SMED30017008 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
rrm2	2.285e-9	47.37	ribonucleotide reductase regulatory subunit M2 [So...	[more]

BLAST of SMED30017008 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
RNR2	8.449e-8	46.30	Ribonucleotide-diphosphate reductase (RNR), small ...	[more]

BLAST of SMED30017008 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO42117	2.072e-9	47.54	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42116	2.892e-9	47.54	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42087	4.820e-9	45.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30017008 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSORLT00000040809.1	8.610e-9	49.12	ribonucleoside-diphosphate reductase subunit M2 [S...	[more]
ENSORLT00000025443.2	2.519e-8	49.12	ribonucleoside-diphosphate reductase subunit M2 [S...	[more]
RRM2	2.778e-8	49.12	ribonucleoside-diphosphate reductase subunit M2-li...	[more]

BLAST of SMED30017008 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4


Match Name	E-value	Identity	Description
SMESG000044184.1	2.766e-24	65.75	SMESG000044184.1	[more]
SMESG000079368.1	2.462e-23	65.75	SMESG000079368.1	[more]
SMESG000044188.1	2.462e-23	65.75	SMESG000044188.1	[more]
SMESG000044184.1	7.065e-23	65.75	SMESG000044184.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30017008 ID=SMED30017008|Name=SMED30017008|organism=Schmidtea mediterranea sexual|type=transcript|length=580bp
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAAAATGG
CCGTTTATTAAAACATTTCCACCCAAAACACATTAAAGGCCCCCGGGGGC
CAAAAGCCGGAATCCCTCAAAAGTCAATATCGAAATGGACATCATCAAAT
TGGGGTTTGCCCTCACCGCTCGACAGGGAATACTCACTGACTCGACGCTA
AAAACAATTAGTTTCCCCATCGAGGCAAATTTTTTCAACAAACAAAAATA
GCCATTTCCACCCAAAACACTTTAATTGCCCCCTGGCCCCAAAAAACGGA
ATCCCTCAAAAATCAATATCGAAATGGACATCATCAAATTGGGGTTGGCC
CTCACCGCTCGACATGGAATTTTCCCCGCCTCGTTTTTAAAAAAAATTAG
TTTTCCCATCGATGCAAATTTTATCCATGAAATCCAACGGGTTCTTTGTG
TTCCAAAACTTGTCACAGCCCANTTAACCCAGCANCCGGNGGGCCACAAN
TTCANTATCCNCNCACNTCGNTTCAGGGTTCATGCCANTCAANTNAAACC
GGCANTGCGTNGGGGANAAATTCCTTTTCG

Annotated Terms

The following terms have been associated with this transcript: