Rap guanine nucleotide exchange factor 4

Query:  251 ILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMD---NNVRAMSIESAGASGLPDDANSQNLS--VPVRTTN-----PGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            I CLDK    R+SED+D I+  LK +K++   HP LL Q+CL   YE+L++ I +++ G    N Y V++GSL +    K+ E  +     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++QK F+ +W K  +++  L L+    VM+   NN R           +PD  N+  +   VP+R  N     P     I+ A   +  +   +L   P     +     + +Q  VG ++V WM Q    ++SR  A+G+WQVLLE+ +L  +   +  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G ++S  NQ N      Y+VM+GTPEKI++H LE  R++   + A          D +L  FI+ +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E    +  ++     + L ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+    +  + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R  + K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   16 IACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVSETSSH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTRESSELLRIEQKDFKALWEKYRQYMAGL-LAPPYGVMETGSNNDR-----------IPDKENTPLIEPHVPLRPANTITKVPSEK--ILRAGKILRNA---ILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEE----LQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAS--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEAT---------DSVLNDFIMMHCVFMPNTQLCPALVAHYH-----------AQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFY-VSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLG-SGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGT-----FELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 1010          

Query:  983 QQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +Q  VG ++V WM Q    ++SR  A+G+WQVLLE+ +L  +   +  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G ++S  NQ N      Y+VM+GTPEKI++H LE  R++   + A          D +L  FI+ +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E    +  ++     + L ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+    +  + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R  + K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   13 RQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEE----LQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAS--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEAT---------DSVLNDFIMMHCVFMPNTQLCPALVAHYH-----------AQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFY-VSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLG-SGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGT-----FELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 790          

Query:  983 QQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +Q  VG ++V WM Q    ++SR  A+G+WQVLLE+ +L  +   +  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G ++S  NQ N      Y+VM+GTPEKI++H LE  R++   + A          D +L  FI+ +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E    +  ++     + L ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+    +  + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R  + K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   62 RQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEE----LQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAS--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEAT---------DSVLNDFIMMHCVFMPNTQLCPALVAHYH-----------AQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFY-VSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLG-SGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGT-----FELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 839          

Query:  983 QQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +Q  VG ++V WM Q    ++SR  A+G+WQVLLE+ +L  +   +  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G ++S  NQ N      Y+VM+GTPEKI++H LE  R++   + A          D +L  FI+ +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E    +  ++     + L ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+    +  + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R  + K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   80 RQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEE----LQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAS--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEAT---------DSVLNDFIMMHCVFMPNTQLCPALVAHYH-----------AQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFY-VSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLG-SGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGT-----FELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 857          

Query:  983 QQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +Q  VG ++V WM Q    ++SR  A+G+WQVLLE+ +L  +   +  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G ++S  NQ N      Y+VM+GTPEKI++H LE  R++   + A          D +L  FI+ +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E    +  ++     + L ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+    +  + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R  + K  PP+IPF  +++KD+TF ++ NKT F DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   89 RQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEE----LQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAS--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEAT---------DSVLNDFIMMHCVFMPNTQLCPALVAHYH-----------AQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFY-VSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLG-SGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGT-----FELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKT-FIDNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 866          

Query:  974 SSTQQVMVGEDMVSWMRQLI-------KINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIP-PIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFG-RITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAK 3454
            +  Q  M+G +M+ W+  L           SR+    IWQVLL   ++  +   +   D  + YY +V  F             +K   + +++  +I  L   AP+ LF MI+ K G ER+ EE E +Y EL  IKALSHLS+MVKRQLS+ +  E +   G VVF QG  G  WYI+LKG+V+V++ GK +VC LR  DDFGKLALVN+ PRAA+I+  E+D  FL +DK  FN+IL  VE NTVRL ++G+DVL+ EK   D P R ++L N N+      YSVMAG  EKI++++LE RID       + D +  + D  +E FILT+ AF+  + +C+ L    ++Y  +TP       I D   +++    K RVV F+Y WC +    FF + V  SF E L   +  ++K            L  + +   +     S +   +   ++H          S      P P+   D+    ++ +     +L + V+ T ++I E   +  +   + L L E+KS+GE+++F   D  +   LS+N K+Y++  EE     +   +  G T   +  SSI       ELA  L  F  QL ++    ELL++V+GR  F   +  NLD  +R+F  +Q+W  TE+      + R+ I+KK I +A+   E +++ + FA+ +GL++++++RL +TW +L     K F +L +LLDPTRNH  +R  + K   P IPF  ++LKDL FI+  NK+++ + ++NFEKM M+A        C+++         M        I+ Q+ +RN + +DNQK+L QLS  +E K
Sbjct:  248 TRVQNCMIGAEMIDWLLTLFVSTSTTCSSLSRIQMSAIWQVLLNNGLISHIDGEHQFLDKTNSYYRWVQQF----------RSRNKVAPSIEEVSKSITLLSSVAPETLFLMIVSKPGFERSPEELEVVYEELTFIKALSHLSTMVKRQLSNFVKVEQYVHAGSVVFRQGEIGVYWYIVLKGAVEVNVNGK-IVCLLREGDDFGKLALVNDLPRAATIVTYEDDSMFLVVDKHHFNQILHQVEANTVRLKDYGEDVLVLEK--VDIP-RGAALENSNSCNFNCGYSVMAGKAEKILEYVLETRIDA------LGDDISEL-DVFVEDFILTHDAFMPDNTVCNFL----KSYYFRTPYRATRDSITDSCTEEVRC--KRRVVQFVYVWCSLLRVNFFLNPVTNSFVEELFCHVIDDRKR-----------LGGMEDILTRIGSIRSTRENMQLVLARHPAIVLDCGVLSAH---TPCPVLPSDVCNQIIYLADTTCFVLPIRVDKTAEEICELSRRRMSFSAEPLNLVEVKSNGEKLIFSPNDRAIPTVLSLNSKLYVVNREEIPL-LVPMEDQNGPT--PSSHSSILHLIDSQELAHQLFLFHLQLLRSTDSNELLYQVIGRESFPLSMPFNLDLLVRRFNEVQHWSTTEILLATE-ENRMEILKKFISIATIAREYRDLLTVFAITLGLSHTSISRLTLTWSKLPPASLKTFSELENLLDPTRNHRMYRLLVSKMSSPYIPFVPLILKDLMFIHQGNKSFY-NGLVNFEKMHMFAKIFRSFRQCKSQ---------MDNGAEHEFIEPQSLIRNLRVIDNQKKLMQLSYEIEPK 1028          

Query: 2459 ESTVQQIIETVAKH-----ENIPVDNLCLCEMKSDG----ERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTP--PPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARP 3316
            E++ Q +++   +      E  P  +LC C +  DG     R+  +ME++     +++N + YL      +    DE     L   +T+L S+    +   +A  LT  D+ +F  I   E L   FK+   SK+G  +  L+ F + F    +WV TE+C  +++Q+R  ++KK IK+A    +L+N +S FA++ GL+  AV RL  +WER+SSK+ ++  ++  L+DP+RN   +RQ+L +    PP++P + ++ KDLTF +D N TY  + +INFEK+++ A S+  V+   + P
Sbjct:  680 ETSAQNVVQLALQEFNMTAEGSPEWSLCECTVTIDGVIKQRRLPPQMENLA--ERIALNSRYYLKNNSRSEPLVPDELAPELLKEAQTQLLSL----NAQVVAAQLTLQDFSVFSAIEPTEFLDNLFKL--DSKYG--SPKLEEFEQLFNREMWWVATEICTERHVQKRAKLIKKFIKVARYCRDLRNFNSMFAIMSGLDKPAVRRLHSSWERVSSKYIRMLDEIHQLVDPSRNMSKYRQHLAEVAQEPPVVPIYPVIKKDLTFAHDGNATY-SEKLINFEKLRLIAKSIRGVMKLSSAP 968          

Query: 1283 RMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDV--ELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVM-AGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDP-MLETFILTYFAFL 1960
            R  L K   ERN E+   +   + H+ A + L   +KRQL   +++ +    G VV     + +SW +I+ G V+V +K  G     +  D FG             +    +DC F+ ++  DF  I+  +   +   R    G+ V   E+R                  G +   V+  G P+K+I HL++ R D N              DP  ++ F+LTY  F+
Sbjct:  197 RECLEKEPSERNSEDLAVLLDFMQHMSAFAALPMSIKRQLCLKMVFAVVNDAGTVVLAHNEKLDSWSVIVNGCVEV-VKPSGERVEYKLGDSFGAEPTPATQIHIGEMRTMVDDCEFVLVEHRDFCSIMSTIGDHIEKDRDGLTGEVVSEVERRT----------------VGTHCGQVLIKGKPDKLIHHLVDER-DHNV-------------DPHYVDDFLLTYRVFI 395          

Query: 2459 ESTVQQIIETVAKH-----ENIPVDNLCLCEMKSDG----ERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTP--PPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARP 3316
            E++ Q +++   +      E  P  +LC C +  DG     R+  +ME++     +++N + YL      +    DE     L   +T+L S+    +   +A  LT  D+ +F  I   E L   FK+   SK+G  +  L+ F + F    +WV TE+C  +++Q+R  ++KK IK+A    +L+N +S FA++ GL+  AV RL  +WER+SSK+ ++  ++  L+DP+RN   +RQ+L +    PP++P + ++ KDLTF +D N TY  + +INFEK+++ A S+  V+   + P
Sbjct:  680 ETSAQNVVQLALQEFNMTAEGSPEWSLCECTVTIDGVIKQRRLPPQMENLA--ERIALNSRYYLKNNSRSEPLVPDELAPELLKEAQTQLLSL----NAQVVAAQLTLQDFSVFSAIEPTEFLDNLFKL--DSKYG--SPKLEEFEQLFNREMWWVATEICTERHVQKRAKLIKKFIKVARYCRDLRNFNSMFAIMSGLDKPAVRRLHSSWERVSSKYIRMLDEIHQLVDPSRNMSKYRQHLAEVAQEPPVVPIYPVIKKDLTFAHDGNATY-SEKLINFEKLRLIAKSIRGVMKLSSAP 968          

Query: 1283 RMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDV--ELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVM-AGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDP-MLETFILTYFAFL 1960
            R  L K   ERN E+   +   + H+ A + L   +KRQL   +++ +    G VV     + +SW +I+ G V+V +K  G     +  D FG             +    +DC F+ ++  DF  I+  +   +   R    G+ V   E+R                  G +   V+  G P+K+I HL++ R D N              DP  ++ F+LTY  F+
Sbjct:  197 RECLEKEPSERNSEDLAVLLDFMQHMSAFAALPMSIKRQLCLKMVFAVVNDAGTVVLAHNEKLDSWSVIVNGCVEV-VKPSGERVEYKLGDSFGAEPTPATQIHIGEMRTMVDDCEFVLVEHRDFCSIMSTIGDHIEKDRDGLTGEVVSEVERRT----------------VGTHCGQVLIKGKPDKLIHHLVDER-DHNV-------------DPHYVDDFLLTYRVFI 395          

Query: 2459 ESTVQQIIETVAKH-----ENIPVDNLCLCEMKSDG----ERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTP--PPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARP 3316
            E++ Q +++   +      E  P  +LC C +  DG     R+  +ME++     +++N + YL      +    DE     L   +T+L S+    +   +A  LT  D+ +F  I   E L   FK+   SK+G  +  L+ F + F    +WV TE+C  +++Q+R  ++KK IK+A    +L+N +S FA++ GL+  AV RL  +WER+SSK+ ++  ++  L+DP+RN   +RQ+L +    PP++P + ++ KDLTF +D N TY  + +INFEK+++ A S+  V+   + P
Sbjct:  638 ETSAQNVVQLALQEFNMTAEGSPEWSLCECTVTIDGVIKQRRLPPQMENLA--ERIALNSRYYLKNNSRSEPLVPDELAPELLKEAQTQLLSL----NAQVVAAQLTLQDFSVFSAIEPTEFLDNLFKL--DSKYG--SPKLEEFEQLFNREMWWVATEICTERHVQKRAKLIKKFIKVARYCRDLRNFNSMFAIMSGLDKPAVRRLHSSWERVSSKYIRMLDEIHQLVDPSRNMSKYRQHLAEVAQEPPVVPIYPVIKKDLTFAHDGNATY-SEKLINFEKLRLIAKSIRGVMKLSSAP 926          

Query: 1283 RMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDV--ELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVM-AGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDP-MLETFILTYFAFL 1960
            R  L K   ERN E+   +   + H+ A + L   +KRQL   +++ +    G VV     + +SW +I+ G V+V +K  G     +  D FG             +    +DC F+ ++  DF  I+  +   +   R    G+ V   E+R                  G +   V+  G P+K+I HL++ R D N              DP  ++ F+LTY  F+
Sbjct:  155 RECLEKEPSERNSEDLAVLLDFMQHMSAFAALPMSIKRQLCLKMVFAVVNDAGTVVLAHNEKLDSWSVIVNGCVEV-VKPSGERVEYKLGDSFGAEPTPATQIHIGEMRTMVDDCEFVLVEHRDFCSIMSTIGDHIEKDRDGLTGEVVSEVERRT----------------VGTHCGQVLIKGKPDKLIHHLVDER-DHNV-------------DPHYVDDFLLTYRVFI 353          

Query: 2459 ESTVQQIIETVAKH-----ENIPVDNLCLCEMKSDG----ERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTP--PPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARP 3316
            E++ Q +++   +      E  P  +LC C +  DG     R+  +ME++     +++N + YL      +    DE     L   +T+L S+    +   +A  LT  D+ +F  I   E L   FK+   SK+G  +  L+ F + F    +WV TE+C  +++Q+R  ++KK IK+A    +L+N +S FA++ GL+  AV RL  +WER+SSK+ ++  ++  L+DP+RN   +RQ+L +    PP++P + ++ KDLTF +D N TY  + +INFEK+++ A S+  V+   + P
Sbjct:  638 ETSAQNVVQLALQEFNMTAEGSPEWSLCECTVTIDGVIKQRRLPPQMENLA--ERIALNSRYYLKNNSRSEPLVPDELAPELLKEAQTQLLSL----NAQVVAAQLTLQDFSVFSAIEPTEFLDNLFKL--DSKYG--SPKLEEFEQLFNREMWWVATEICTERHVQKRAKLIKKFIKVARYCRDLRNFNSMFAIMSGLDKPAVRRLHSSWERVSSKYIRMLDEIHQLVDPSRNMSKYRQHLAEVAQEPPVVPIYPVIKKDLTFAHDGNATY-SEKLINFEKLRLIAKSIRGVMKLSSAP 926          

Query: 1283 RMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDV--ELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVM-AGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDP-MLETFILTYFAFL 1960
            R  L K   ERN E+   +   + H+ A + L   +KRQL   +++ +    G VV     + +SW +I+ G V+V +K  G     +  D FG             +    +DC F+ ++  DF  I+  +   +   R    G+ V   E+R                  G +   V+  G P+K+I HL++ R D N              DP  ++ F+LTY  F+
Sbjct:  155 RECLEKEPSERNSEDLAVLLDFMQHMSAFAALPMSIKRQLCLKMVFAVVNDAGTVVLAHNEKLDSWSVIVNGCVEV-VKPSGERVEYKLGDSFGAEPTPATQIHIGEMRTMVDDCEFVLVEHRDFCSIMSTIGDHIEKDRDGLTGEVVSEVERRT----------------VGTHCGQVLIKGKPDKLIHHLVDER-DHNV-------------DPHYVDDFLLTYRVFI 353          

Query:  251 ILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPD----DANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSS-FGGKIVSKSSTQQVMVGEDMVSWMRQLIKI-NSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKS---FQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQ---NYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKF--SKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAK--HENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSI-FDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            I  +DK    R   D++ I   L+ ++    L    LQQ+ +   YE L++ + +++ G+  +  Y V+ GSL +          + D + +  +    +  G  FG +   +            L     VVT+  CELL ++Q+ F+ IW KN++ + D+  +  +     N    S+++  A+  P       +  N ++P+  T    +PA+    + +    + LLV+  SS    + VS    ++   G ++V W+  L  I ++R  A G+WQ LLEE +L  +      +D    Y   +D+      GG  A+G  ++       + +  A++ L +  PDA  RMIL K   ER  EE E ++ EL+HI ALSHLS+ +KR+LSS+ ++E H   G ++F QG EG SWYI+LKGSVDV I GKG V  L+T DDFGKLAL+N++PRAA+I+L+EN+CH L++DKE FNRILRDVE NT+RL EHGKDVL+ E R+    G+ S+          + Y+VM+GTP K+++HLLE R+  +         VG + DP L+ F+LT+  F+    L   L  YF    + + QTP        ED+E+   ++  K RV+ F+  W      A FE+  +  F E+L     A +  ++  LN+E   ++ +L Q  + +   ++  GQ+ K   +   I   + NAT  + V    I+  D   F V+ +    C LR  + +T + I    A     N   ++L L E+KS+GER +F+  DV +   LS+NG++++       ++ LD    +      TE   I  +  S  ELA+H+T F+W LF  +H YELL+   GR  FG+IT+NLD F+R+F  +QYW+VTE+    +L +RV +V+K IKLA+   E +N+++ FAV+MGL+N AV+RLQ TWE++ SK RK+FQ+  +L+DP+RNH A+R ++ K  PP+IPF  ++LKD+TF ++ NKT   D ++NFEKM M A +M  +  CR+R +  E  +   +       ++++Y+ +F+ +DNQ+ LT +S  +E
Sbjct:    6 ITAMDKRPCDRNLRDVELISCRLRRVEPLCRLPGSALQQLAMCGFYEDLEKGVTLFRAGEQGRFWYAVLGGSLEVRYH------AHADADGKSAVTLCNLGVGATFGESVLHD------------LPRDSTVVTKTTCELLRVEQQDFRLIWEKNKELMNDIFTNCKL----KNGFGPSVQATAAATSPTKRPLSPDHPNPALPITETP---SPAMNRMGWAL----RTLLVADNSSCLKDRKVSGKLIRKCAPGTELVDWLVNLSPIVHTRAQAAGMWQALLEEGVLAHVNKEQPFKDKCFLYRFRIDE-----EGGTAAAGVPQAEDLGAANEHIREALSALFQRGPDATLRMILRKPSHERTSEELELVFEELVHIAALSHLSTSIKRELSSIFVFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTGDDFGKLALINDAPRAATIVLKENNCHLLRVDKEHFNRILRDVEANTLRLQEHGKDVLVLE-RVAKQRGQHSA----------FKYTVMSGTPAKMLEHLLETRLGQS---------VGGM-DPFLDDFLLTHIVFMPVVQLVDELANYFHCDAHEDAQTP--------EDREY---IINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDL-----AAEVEADPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTV----IRPDDDIIFRVYCADHTYCTLRFPMHTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSVFKDNDVSIPTGLSLNGRLFVSV-----KDHLDALTQLQEQECPTEGVDIDLEILSTKELAYHITLFEWDLFWAVHEYELLYHTFGRHHFGKITANLDVFLRRFNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFEALIDPSRNHRAYRVFVGKLQPPLIPFMPLLLKDMTFAHEGNKTSL-DGLVNFEKMHMMAQTMRTIRFCRSRSLGLEPPSPKSEG------EVRSYISSFRVIDNQRVLTAMSQKVE 1001          

Query:  623 NLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPD----DANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSS-FGGKIVSKSSTQQVMVGEDMVSWMRQLIKI-NSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKS---FQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQ---NYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSK--HQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAK--HENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSI-FDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +L     VVT+  CELL ++Q+ F+ IW KN++ + D+  +  +     N    S+++  A+  P       +  N ++P+  T    +PA+    + +    + LLV+  SS    + VS    ++   G ++V W+  L  I ++R  A G+WQ LLEE +L  +      +D    Y   +D+      GG  A+G  ++       + +  A++ L +  PDA  RMIL K   ER  EE E ++ EL+HI ALSHLS+ +KR+LSS+ ++E H   G ++F QG EG SWYI+LKGSVDV I GKG V  L+T DDFGKLAL+N++PRAA+I+L+EN+CH L++DKE FNRILRDVE NT+RL EHGKDVL+ E R+    G+ S+          + Y+VM+GTP K+++HLLE R+  +         VG + DP L+ F+LT+  F+    L   L  YF    + + QTP        ED+E+   ++  K RV+ F+  W      A FE+  +  F E+L     A +  ++  LN+E   ++ +L Q  + +   ++  GQ+ K       I   + NAT  + V    I+  D   F V+ +    C LR  + +T + I    A     N   ++L L E+KS+GER +F+  DV +   LS+NG++++       ++ LD    +      TE   I  +  S  ELA+H+T F+W LF  +H YELL+   GR  FG+IT+NLD F+R+F  +QYW+VTE+    +L +RV +V+K IKLA+   E +N+++ FAV+MGL+N AV+RLQ TWE++ SK RK+FQ+  +L+DP+RNH A+R ++ K  PP+IPF  ++LKD+TF ++ NKT   D ++NFEKM M A +M  +  CR+R +  E  +   +       ++++Y+ +F+ +DNQ+ LT +S  +E
Sbjct:   41 DLPRDSTVVTKTTCELLRVEQQDFRLIWEKNKELMNDIFTNCKL----KNGFGPSVQATAAATSPTKRPLSPDHPNPALPITETP---SPAMNRMGWAL----RTLLVADNSSCLKDRKVSGKLIRKCAPGTELVDWLVNLSPIVHTRAQAAGMWQALLEEGVLAHVNKEQPFKDKCFLYRFRIDE-----EGGTAAAGVPQAEDLGAANEHIREALSALFQRGPDATLRMILRKPSHERTSEELELVFEELVHIAALSHLSTSIKRELSSIFVFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTGDDFGKLALINDAPRAATIVLKENNCHLLRVDKEHFNRILRDVEANTLRLQEHGKDVLVLE-RVAKQRGQHSA----------FKYTVMSGTPAKMLEHLLETRLGQS---------VGGM-DPFLDDFLLTHIVFMPVVQLVDELANYFHCDAHEDAQTP--------EDREY---IINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDL-----AAEVEADPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTV----IRPDDDIIFRVYCADHTYCTLRFPMHTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSVFKDNDVSIPTGLSLNGRLFVSV-----KDHLDALTQLQEQECPTEGVDIDLEILSTKELAYHITLFEWDLFWAVHEYELLYHTFGRHHFGKITANLDVFLRRFNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFEALIDPSRNHRAYRVFVGKLQPPLIPFMPLLLKDMTFAHEGNKTSL-DGLVNFEKMHMMAQTMRTIRFCRSRSLGLEPPSPKSEG------EVRSYISSFRVIDNQRVLTAMSQKVE 930          

Query:  956 GKIVSKSSTQQVMVGEDMVSWMRQLIKI-NSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKS---FQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQ---NYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSK--HQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAK--HENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSI-FDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            GK++ K +      G ++V W+  L  I ++R  A G+WQ LLEE +L  +      +D    Y   +D+      GG  A+G  ++       + +  A++ L +  PDA  RMIL K   ER  EE E ++ EL+HI ALSHLS+ +KR+LSS+ ++E H   G ++F QG EG SWYI+LKGSVDV I GKG V  L+T DDFGKLAL+N++PRAA+I+L+EN+CH L++DKE FNRILRDVE NT+RL EHGKDVL+ E R+    G+ S+          + Y+VM+GTP K+++HLLE R+  +         VG + DP L+ F+LT+  F+    L   L  YF    + + QTP        ED+E+   ++  K RV+ F+  W      A FE+  +  F E+L     A +  ++  LN+E   ++ +L Q  + +   ++  GQ+ K       I   + NAT  + V    I+  D   F V+ +    C LR  + +T + I    A     N   ++L L E+KS+GER +F+  DV +   LS+NG++++       ++ LD    +      TE   I  +  S  ELA+H+T F+W LF  +H YELL+   GR  FG+IT+NLD F+R+F  +QYW+VTE+    +L +RV +V+K IKLA+   E +N+++ FAV+MGL+N AV+RLQ TWE++ SK RK+FQ+  +L+DP+RNH A+R ++ K  PP+IPF  ++LKD+TF ++ NKT   D ++NFEKM M A +M  +  CR+R +  E  +   +       ++++Y+ +F+ +DNQ+ LT +S  +E
Sbjct:   77 GKLIRKCAP-----GTELVDWLVNLSPIVHTRAQAAGMWQALLEEGVLAHVNKEQPFKDKCFLYRFRIDE-----EGGTAAAGVPQAEDLGAANEHIREALSALFQRGPDATLRMILRKPSHERTSEELELVFEELVHIAALSHLSTSIKRELSSIFVFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTGDDFGKLALINDAPRAATIVLKENNCHLLRVDKEHFNRILRDVEANTLRLQEHGKDVLVLE-RVAKQRGQHSA----------FKYTVMSGTPAKMLEHLLETRLGQS---------VGGM-DPFLDDFLLTHIVFMPVVQLVDELANYFHCDAHEDAQTP--------EDREY---IINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDL-----AAEVEADPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTV----IRPDDDIIFRVYCADHTYCTLRFPMHTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSVFKDNDVSIPTGLSLNGRLFVSV-----KDHLDALTQLQEQECPTEGVDIDLEILSTKELAYHITLFEWDLFWAVHEYELLYHTFGRHHFGKITANLDVFLRRFNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFEALIDPSRNHRAYRVFVGKLQPPLIPFMPLLLKDMTFAHEGNKTSL-DGLVNFEKMHMMAQTMRTIRFCRSRSLGLEPPSPKSEG------EVRSYISSFRVIDNQRVLTAMSQKVE 856          

Query:  956 GKIVSKSSTQQVMVGEDMVSWMRQLIKI-NSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKS---FQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQ---NYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSK--HQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAK--HENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSI-FDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            GK++ K +      G ++V W+  L  I ++R  A G+WQ LLEE +L  +      +D    Y   +D+      GG  A+G  ++       + +  A++ L +  PDA  RMIL K   ER  EE E ++ EL+HI ALSHLS+ +KR+LSS+ ++E H   G ++F QG EG SWYI+LKGSVDV I GKG V  L+T DDFGKLAL+N++PRAA+I+L+EN+CH L++DKE FNRILRDVE NT+RL EHGKDVL+ E R+    G+ S+          + Y+VM+GTP K+++HLLE R+  +         VG + DP L+ F+LT+  F+    L   L  YF    + + QTP        ED+E+   ++  K RV+ F+  W      A FE+  +  F E+L     A +  ++  LN+E   ++ +L Q  + +   ++  GQ+ K       I   + NAT  + V    I+  D   F V+ +    C LR  + +T + I    A     N   ++L L E+KS+GER +F+  DV +   LS+NG++++       ++ LD    +      TE   I  +  S  ELA+H+T F+W LF  +H YELL+   GR  FG+IT+NLD F+R+F  +QYW+VTE+    +L +RV +V+K IKLA+   E +N+++ FAV+MGL+N AV+RLQ TWE++ SK RK+FQ+  +L+DP+RNH A+R ++ K  PP+IPF  ++LKD+TF ++ NKT   D ++NFEKM M A +M  +  CR+R +  E  +   +       ++++Y+ +F+ +DNQ+ LT +S  +E
Sbjct:   77 GKLIRKCAP-----GTELVDWLVNLSPIVHTRAQAAGMWQALLEEGVLAHVNKEQPFKDKCFLYRFRIDE-----EGGTAAAGVPQAEDLGAANEHIREALSALFQRGPDATLRMILRKPSHERTSEELELVFEELVHIAALSHLSTSIKRELSSIFVFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTGDDFGKLALINDAPRAATIVLKENNCHLLRVDKEHFNRILRDVEANTLRLQEHGKDVLVLE-RVAKQRGQHSA----------FKYTVMSGTPAKMLEHLLETRLGQS---------VGGM-DPFLDDFLLTHIVFMPVVQLVDELANYFHCDAHEDAQTP--------EDREY---IINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDL-----AAEVEADPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTV----IRPDDDIIFRVYCADHTYCTLRFPMHTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSVFKDNDVSIPTGLSLNGRLFVSV-----KDHLDALTQLQEQECPTEGVDIDLEILSTKELAYHITLFEWDLFWAVHEYELLYHTFGRHHFGKITANLDVFLRRFNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFEALIDPSRNHRAYRVFVGKLQPPLIPFMPLLLKDMTFAHEGNKTSL-DGLVNFEKMHMMAQTMRTIRFCRSRSLGLEPPSPKSEG------EVRSYISSFRVIDNQRVLTAMSQKVE 856          

Query: 2732 ELAFHLTYFDWQLFKNIHVYEL---LFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKK---TPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTI 3370
            ELA  LT  D+  F+ I   E    LF++  RS++G     L  F        +WVV+E+C   N+ RR+ IVK+ IK+A    E +N +S FA++ GL + AV+RL+ TWE+L SK+++LF DL  L+DP+RN   +RQ +        PIIPF+ I+ KDLTFI+  N T   D +INFEK++M A  +  + H  + P    +   +K    SN +
Sbjct:  871 ELAIQLTLQDFANFRQIESTEYVDELFEL--RSRYG--VPMLSKFAELVNREMFWVVSEICAEHNIVRRMKIVKQFIKIARHCKECRNFNSMFAIVSGLGHGAVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAELLAQHPIIPFYPIVKKDLTFIHLGNDTRV-DGLINFEKLRMLAKEVRLLTHMCSSPYDLLSILELKGQSPSNAL 1084          

Query: 1283 RMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLT-EHGKDVLLFEKRI-----TDSPGRKSSLMNQNNPTGFYM-YSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTS-HGLCSLLLVYF 1999
            R  L K   ER++E+ E +      +KA ++++  V+R L SV+++ +    G VV   G E +SW +++ G+V++     G    L+  D FG L  ++       +  + +DC F+ I + D+ RI    E NT R   E+G  V++ E R      TDS G   S    +        + V+ GTPE+++  L+E    T+ +Y              +E F+LT+  F+ +   + S LL +F
Sbjct:  101 RDCLEKDPAERSEEDVEVLLEFTQGLKAFTNITLAVRRALCSVMVFAVVDKAGTVVMSDGEELDSWSVLINGAVEIE-HANGSREELQMGDSFGILPTMDKLYHRGVMRTKCDDCQFVCITQTDYYRIQHQGEENTRRHEDENGFVVMVTELRSIGGAGTDSAGSGGSATGASASLNMKRGHVVIRGTPERLLQQLVEENSMTDPTY--------------VEDFLLTHRIFIQNPQEVTSKLLHWF 332          

Query:  242 AKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPA--IINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLA-LNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELS-SIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            A+ I+CLDK    R+ ED+D I   LK +K++   HP LLQQ+C+   YE+L++ I +Y+ G    + Y V+SGSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +V++E+ ELL ++Q+ F+ +W K  + +  L L+    VMD+         A    +PD  N  N  +   + N    P+  I+ A   +  +   +L   P     +     + +Q  VG ++V W+ +Q   ++SR  A+G+WQVLLEE +L  +      +D    +Y F+DD             + +  +  ++L+  + +L +  PDA  RMIL K   +R  E+ E IY ELLHIKA+SHLS+ VKR+L+ VL++E H   G V+F QG EG SWYII KGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ +K +  S        +  N    + Y+VM+G+PEKI++HLLE  R+D + S           PDP L+ F+L +  F+ +  LC  LL ++ +  +Q     R             +  K RV+     W  +      ED     F E L   ++ + +    L  KE L  L  +++Q+             RS   KH++  +  ++  ++L    PI+  D     V+ S      +R+ V +T +++   VA       + L L  + + GE+ + +  DV V  +L VNG++++   E      LD  N +      +  S S F+  S  +LAF +T +DW+LF  +H YEL++   GR  + R T+NL+ F+R+F  +Q WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MG+ N AV+RL  TWE+L SK +K + +  SLLDP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT+  D ++NFEKM++ A ++  V HCR++P   E S + K     N  +++NYVR    +DNQ+ L+QLS  LE ++
Sbjct:   14 AEWIICLDKRPAERSGEDVDIILARLKGVKAFEKFHPNLLQQICMCGFYEYLEKGITLYRQGDIGTSWYAVLSGSLDV----KVSETANH----QDAVTICTLGVGTAFGESI-LDNTPRH-----------ATIVSRENSELLRIEQREFKTLWEKYRQCMAGL-LAPPYGVMDSG--------ATNDRMPDKDNLSNDPLNFMSKNLNKVPSEKILRAEKVLRNA---ILARAPHMIRDRKYHLKTYRQCCVGTELVDWLLQQSSCVHSRAHAVGMWQVLLEEGVLNHVDHELNFQDKYL-FYRFLDD----EEEDAVLPSDDEKREAEEELQETLLFLSQIGPDAHMRMILRKPPGQRTAEDLEIIYDELLHIKAVSHLSNTVKRELAGVLIFESHAKAGTVLFNQGEEGTSWYIIQKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHEQDVLVLQKSLRPS--------SHGNIPAHFKYTVMSGSPEKILEHLLETMRLDIHFSD----------PDPALDDFVLMHCVFMPNSQLCPALLAHYHSQASQGSEQDRL---------DYAVASKRRVLSLALRWAALQAHHLLEDDTALGFLEELHGFVSNDARVLRPL--KELLPELEKIIKQYPDD---------ARSSQKKHKVLLRQFSSGEERLAKKQPIRSFDDILLKVYCSDHTYTTIRVPVLATGREVTAAVADKLG-STEELLLINLSASGEKQILKPNDVSVFQSLGVNGRMFVCPRE-----LLDSLNPLPEQEGPSTGSMSSFELMSSKDLAFQMTQYDWELFSCVHEYELVYHTFGRQAYRRSTANLELFLRRFNQLQLWVVTEVCLCGTLSKRVQLLKKFIKIAAHCREFKNLNSFFAIIMGMCNPAVSRLIQTWEKLPSKFKKFYAEFESLLDPSRNHRAYRLTVAKMEPPIIPFMPLLIKDMTFTHEGNKTFI-DGLVNFEKMRLIANTVRAVRHCRSQPFNAEASPASK-----NPQEVRNYVRQLTVIDNQRTLSQLSFRLEPRR 1004          

Query:  233 SQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIIN--AAFFIYKSSKHL----LVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            S  A  I+CLDK    R+ ED+D I   LK +K++   HP LLQQ+CL   YE L++ I +Y+ G    N Y V+SGSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++QK F+ +W    + +  L L     VMD+           A  +PD  N  N       ++PG +P  +N   +  I ++ K L    L   P     +     + ++  +G ++V W+ Q    ++SR+ A+G+WQVLLEE +L  +      +D    +Y F+DD         G        ++ ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE+ CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK             N+++ +    Y+VM+GTPEKI++HLLE          + LD   +  DP L+ F+L +  F+ +  LC LL+  + +             I ++E     L  K RVV  +  W  I+     E+    SF +    ++  + + + +L +         L + +K  I  +   G+ S+  KH++  +  +  + +L    PIK  D   F V+ S      +R+ V ++V+++I  V+   +   D+L L  + S G++ L +  DV +  +LS+NG++++   ++      L E+      ++ T     F+  S  +LA  +T +DW+LF  +H +EL++   GR  F + T+NLD F+R+F  +Q WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MGL N AV RL  TWE+L SK +K + +  +L+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT F D ++NFEKM+M A ++  + +CR++P   E   +  K       D++ YVR+   +DNQ+ L+QLS  LE ++
Sbjct:   16 SASADWIVCLDKRPEERSGEDVDIIMVRLKSVKAFEKFHPPLLQQICLCGFYECLEKGITLYRQGDIGTNWYTVLSGSLDV----KVSETANH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTREFSELLRIEQKDFRNLWENYRQCMAGL-LVPPYGVMDSG--------PNADRMPDKENLSN-------SSPGLSPKHLNKVPSEKILRAGKVLRNIILSRAPHMIRDRKYHLKTYRRSCIGTELVDWLLQHTSCVHSRVQAVGMWQVLLEEGVLNHVDQEPTFQDKYL-FYRFLDD----ESEDSGMPSEEDKKESDEELQDTLLLLSQIGPDAHLRMILRKQPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDFCHFLRVDKEDFNRILRDVEANTVRLKEHEEDVLVLEK-----------ANNRSSSSSPLKYTVMSGTPEKILEHLLE---------TMKLDCQFSESDPALDDFLLMHCVFVPNSQLCPLLMTQYPSL------------INEQERMDYTLNNKRRVVRLVLQWASINTDHLQEEDSSFSFIQEFYEMVCEDSRLTPALKDH--------LPELEKI-IKQNSDDGRPSQ-KKHKVLLRQFSTGNDRLQKRQPIKSTDEILFKVYCSDHTYSTIRVPVSASVREVIAAVSDKLS-SGDDLLLIHLNSAGDKELLKPSDVSIFSSLSINGRLFVCPRDQIDSLTPLPEQEGPSAGSMST-----FELMSSKDLAHQMTLYDWELFHCVHEHELIYHTFGRHHFKKTTANLDLFLRRFNEVQLWVVTEVCLCPALSKRVQLLKKFIKIAAHCKEFKNLNSFFAIIMGLGNPAVCRLSQTWEKLPSKFKKFYGEFENLMDPSRNHRAYRLTMAKLEPPIIPFMPLLIKDMTFTHEGNKT-FTDRLVNFEKMRMIANTVRIIRYCRSQPFDQEAPQATGKSHQ----DVRTYVRHISVIDNQRSLSQLSHRLEPRR 1004          

Query: 1262 PAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKG------VVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRI 1666
            P+  A + + L K  +ER+ E+ + I   L  +KA       + +Q+     YE     G  ++ QG  G +WY +L GS+DV +           +C L     FG+ ++++N+PR A+I+ RE     L+I+++DF  +
Sbjct:   15 PSASADWIVCLDKRPEERSGEDVDIIMVRLKSVKAFEKFHPPLLQQICLCGFYECLE-KGITLYRQGDIGTNWYTVLSGSLDVKVSETANHQDAVTICTLGIGTAFGE-SILDNTPRHATIVTREFS-ELLRIEQKDFRNL 152          

Query:  233 SQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIIN--AAFFIYKSSKHL----LVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQN------YNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            S  A  I+CLDK    R+ ED+D I   LK +K++   HP LLQQ+CL   YE L++ I +Y+ G    N Y V+SGSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++QK F+ +W    + +  L L     VMD+           A  +PD  N  N       ++PG +P  +N   +  I ++ K L    L   P     +     + ++  +G ++V W+ Q    ++SR+ A+G+WQVLLEE +L  +      +D    +Y F+DD         G        ++ ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE+ CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK             N+++ +    Y+VM+GTPEKI++HLLE          + LD   +  DP L+ F+L +  F+ +  LC LL+  + +      ++ +TP+  +A+   ++E     L  K RVV  +  W  I+     E+    SF +    ++  + + + +L +         L + +K  I  +   G+ S+  KH++  +  +  + +L    PIK  D                                  EN                + L +  DV +  +LS+NG++++   ++      L E+      ++ T     F+  S  +LA  +T +DW+LF  +H +EL++   GR  F + T+NLD F+R+F  +Q WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MGL N AV RL  TWE+L SK +K + +  +L+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT F D ++NFEKM+M A ++  + +CR++P   E   +  K       D++ YVR+   +DNQ+ L+QLS  LE ++
Sbjct:   16 SASADWIVCLDKRPEERSGEDVDIIMVRLKSVKAFEKFHPPLLQQICLCGFYECLEKGITLYRQGDIGTNWYTVLSGSLDV----KVSETANH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTREFSELLRIEQKDFRNLWENYRQCMAGL-LVPPYGVMDSG--------PNADRMPDKENLSN-------SSPGLSPKHLNKVPSEKILRAGKVLRNIILSRAPHMIRDRKYHLKTYRRSCIGTELVDWLLQHTSCVHSRVQAVGMWQVLLEEGVLNHVDQEPTFQDKYL-FYRFLDD----ESEDSGMPSEEDKKESDEELQDTLLLLSQIGPDAHLRMILRKQPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDFCHFLRVDKEDFNRILRDVEANTVRLKEHEEDVLVLEK-----------ANNRSSSSSPLKYTVMSGTPEKILEHLLE---------TMKLDCQFSESDPALDDFLLMHCVFVPNSQLCPLLMTQYPSLIKPYCFSTKTPH--QASQGSEQERMDYTLNNKRRVVRLVLQWASINTDHLQEEDSSFSFIQEFYEMVCEDSRLTPALKDH--------LPELEKI-IKQNSDDGRPSQ-KKHKVLLRQFSTGNDRLQKRQPIKSTD----------------------------------EN----------------KELLKPSDVSIFSSLSINGRLFVCPRDQIDSLTPLPEQEGPSAGSMST-----FELMSSKDLAHQMTLYDWELFHCVHEHELIYHTFGRHHFKKTTANLDLFLRRFNEVQLWVVTEVCLCPALSKRVQLLKKFIKIAAHCKEFKNLNSFFAIIMGLGNPAVCRLSQTWEKLPSKFKKFYGEFENLMDPSRNHRAYRLTMAKLEPPIIPFMPLLIKDMTFTHEGNKT-FTDRLVNFEKMRMIANTVRIIRYCRSQPFDQEAPQATGKSHQ----DVRTYVRHISVIDNQRSLSQLSHRLEPRR 971          

Query: 1262 PAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKG------VVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRI 1666
            P+  A + + L K  +ER+ E+ + I   L  +KA       + +Q+     YE     G  ++ QG  G +WY +L GS+DV +           +C L     FG+ ++++N+PR A+I+ RE     L+I+++DF  +
Sbjct:   15 PSASADWIVCLDKRPEERSGEDVDIIMVRLKSVKAFEKFHPPLLQQICLCGFYECLE-KGITLYRQGDIGTNWYTVLSGSLDVKVSETANHQDAVTICTLGIGTAFGE-SILDNTPRHATIVTREFS-ELLRIEQKDFRNL 152          

Query:  767 NNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIKIN----SRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVD---DFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAAS-----KKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKF-GRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMI------------FENSTSMKKDKLSN-------TIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +N +   I     + LPD  ++Q+      T     +  I+ AA  +Y +   L+   P     +     + +Q   G+++V W   L+K+N    SR  A+G+WQVL++E IL  +       D  + +Y F++   D  H        + N K  +  D+L+ +++ L++  PDAL  MIL K   +R  E+ E IY ELLH+KA++HLS+ V+++L+SVL++E H   G V+F QG +G SWYII +GSV+V   GKG+V  L   DDFG+LALVN++PRAA+IILRE++CHFL++DK+DF RIL+DVE NTVRL EHGK VL+ EK    S  + +   N+        Y+VM+GTPEKI++H+LE  +++TN +  +         DP +  F+LT+  F+    LC+ L    Q++    P++G      D E     L  K +VV  +  W  +      +D V   F E     + A+ + S+ L  +        L   +KT+I  +      K+ Q+  +          +A  + +  +  IK +D   + +     ++  + L V+++V  I+ T+      P  N  L +M S G+R+  ++E   V  +L VN K++L    +  E    ++  +G    K+ + ++    S D  + H +Y DW+LF  +H  EL++ V GR KF G  T+NL+ F+R+F  +QYWVVTE+C C++L +R  ++KK IK+A  L E KN++S FAV+ GL+NSAV RL  TWERL +K ++++     L+DP+RNH A+R  + K  PP IPF  ++LKD+TFI++ NK Y  D ++NFEKM+M A ++  V  CR++P +            F ++ +++    S+          ++ Y++N K +DNQK+LTQLS  LE
Sbjct:   17 SNEKTPQIRGISWTPLPDAVDTQD------TIKQFLSDRILKAARVVYST---LMEGNPGLIRDRKHHLKTYRQCCSGKELVDW---LMKLNDCFQSRSQAVGMWQVLVDEGILGHVKQELNFHDKDTQFYRFMEAEFDLNH--------TTNEKDSKD-DELQESLSLLIQMGPDALLTMILRKCPSQRTPEDLEVIYEELLHVKAVAHLSTSVRKELASVLVFESHAKAGTVLFSQGDKGTSWYIIWRGSVNVITHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFIRILKDVEANTVRLEEHGKVVLVLEK----SSAQDTPSCNK--------YTVMSGTPEKILEHMLEAIKLETNGADFI---------DPCVTDFLLTHPVFMPCSQLCAAL----QHHYQAEPSEG-----SDLEKAAYALNTKQKVVKLVCHWVALFALLLRDDPVASEFLEKFREGVMADSRLSSMLREQ--------LRDRRKTKIMENGCHTLTKLNQKFDW---------FSAYEEPVGKLRSIKAQDKVLYEIFKPDHKAVTVMLPVDASVNDILTTLVD----PDRNYVLVKMNSSGDRVQLKLETTAVSASLGVNEKLFLCTSSQV-EQLTPDKEQLGPE--KSTMDTLEQICSKDMASQHTSY-DWELFMAMHEVELVYYVFGREKFPGSTTANLERFVRRFNEVQYWVVTELCLCEDLGKRAILLKKFIKMAVVLKEQKNLNSFFAVMFGLSNSAVQRLNKTWERLPNKTKRIYCAYERLMDPSRNHRAYRLTIAKLSPPYIPFMPLLLKDMTFIHEGNKNY-TDKLVNFEKMRMIARTVKTVRDCRSQPYVPSSPQKGLTERMFLDAQAIRISTYSDQSLNLRSATSIRQYIQNLKVIDNQKKLTQLSRALE 866          

Query:  884 IINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIKIN----SRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVD---DFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAAS-----KKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKF-GRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMI------------FENSTSMKKDKLSN-------TIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            I+ AA  +Y +   L+   P     +     + +Q   G+++V W   L+K+N    SR  A+G+WQVL++E IL  +       D  + +Y F++   D  H        + N K  +  D+L+ +++ L++  PDAL  MIL K   +R  E+ E IY ELLH+KA++HLS+ V+++L+SVL++E H   G V+F QG +G SWYII +GSV+V   GKG+V  L   DDFG+LALVN++PRAA+IILRE++CHFL++DK+DF RIL+DVE NTVRL EHGK VL+ EK    S  + +   N+        Y+VM+GTPEKI++H+LE  +++TN +  +         DP +  F+LT+  F+    LC+ L      Y    P++G      D E     L  K +VV  +  W  +      +D V   F E     + A+ + S+ L  +        L   +KT+I  +      K+ Q+  +          +A  + +  +  IK +D   + +     ++  + L V+++V  I+ T+      P  N  L +M S G+R+  ++E   V  +L VN K++L    +  E    ++  +G    K+ + ++    S D  + H +Y DW+LF  +H  EL++ V GR KF G  T+NL+ F+R+F  +QYWVVTE+C C++L +R  ++KK IK+A  L E KN++S FAV+ GL+NSAV RL  TWERL +K ++++     L+DP+RNH A+R  + K  PP IPF  ++LKD+TFI++ NK Y  D ++NFEKM+M A ++  V  CR++P +            F ++ +++    S+          ++ Y++N K +DNQK+LTQLS  LE
Sbjct:    6 ILKAARVVYST---LMEGNPGLIRDRKHHLKTYRQCCSGKELVDW---LMKLNDCFQSRSQAVGMWQVLVDEGILGHVKQELNFHDKDTQFYRFMEAEFDLNH--------TTNEKDSKD-DELQESLSLLIQMGPDALLTMILRKCPSQRTPEDLEVIYEELLHVKAVAHLSTSVRKELASVLVFESHAKAGTVLFSQGDKGTSWYIIWRGSVNVITHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFIRILKDVEANTVRLEEHGKVVLVLEK----SSAQDTPSCNK--------YTVMSGTPEKILEHMLEAIKLETNGADFI---------DPCVTDFLLTHPVFMPCSQLCAALQ---HQYPYTEPSEG-----SDLEKAAYALNTKQKVVKLVCHWVALFALLLRDDPVASEFLEKFREGVMADSRLSSMLREQ--------LRDRRKTKIMENGCHTLTKLNQKFDW---------FSAYEEPVGKLRSIKAQDKVLYEIFKPDHKAVTVMLPVDASVNDILTTLVD----PDRNYVLVKMNSSGDRVQLKLETTAVSASLGVNEKLFLCTSSQV-EQLTPDKEQLGPE--KSTMDTLEQICSKDMASQHTSY-DWELFMAMHEVELVYYVFGREKFPGSTTANLERFVRRFNEVQYWVVTELCLCEDLGKRAILLKKFIKMAVVLKEQKNLNSFFAVMFGLSNSAVQRLNKTWERLPNKTKRIYCAYERLMDPSRNHRAYRLTIAKLSPPYIPFMPLLLKDMTFIHEGNKNY-TDKLVNFEKMRMIARTVKTVRDCRSQPYVPSSPQKGLTERMFLDAQAIRISTYSDQSLNLRSATSIRQYIQNLKVIDNQKKLTQLSRALE 823          

Query:  233 SQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMD--NNVRAMSIESAGASGLPDDANSQNLSV--------PVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFS--KHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +  A+ I CLDK    R+ ED+D I+  LK +K++   HP LLQQ+C    YE+L++ I +Y+ G    + Y V++GSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E+ ELL ++QK F+ +W K  +++    L+    V++  +N R    E+  ++  P   N     +        P +T     +  I+ A   +  +   +L   P     +     + +Q  VG ++V W M+Q   ++SR  A+G+WQVLLEE +L  +   Y  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R+ ++ E I+ EL+HIKALSHLS+ VKR+L+  L++E HP  G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK +  S G       Q N    Y Y+VM+G PEK+++H LE  R+D + + A          D  L+ FIL +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E     ++ + + + +           L EQ    E  A K+I + +K    KH++  +  +   ++L     I+  D   F V+        +R+ V ++V++++  VA       D+L L ++ S GE+++ +  ++ V   LSVNG+++    +++     L E+       + T     F+  S  +LA+ +T  DW LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K++ +  +L+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT+  DN++NFEKM+M A ++  + +CR+ P   + S + K     N  D++NYVR F  +DNQ+ L+Q+S  LE ++
Sbjct:   10 TSSAEWIACLDKRPLERSGEDVDIIFARLKEVKAFERFHPNLLQQICFCGYYENLEKGITLYRQGDIGTSWYAVLTGSLDV----KVSETNNH----QDAVVICTLGVGTAFGESI-LDNTPRH-----------ATIVTRENSELLRIEQKDFKTLWEKYRQYMAGF-LAPPYGVLETGSNDRLSDKENMNSALGPGSKNCNKTPLIENQIPIRPAKTITEVPSERILRAGKTLRNA---ILTRAPHMIRDRKYHLKTYRQCCVGTELVDWLMQQSSCVHSRTQAVGMWQVLLEEGVLNHVDQEYYFQDKYL-FYRFLDDEHEDAPMPTEEEKKESDEE----LQDTLLLLSQIGPDAHMRMILRKPPGQRSADDLEIIFEELIHIKALSHLSTTVKRELAGFLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKILAGSQGSA-----QGNTQSPYKYTVMSGNPEKLLEHFLETMRLDPSLNDAT---------DTALDDFILMHCVFMPNSQLCPALMSHYH-----------AQPSQGTEQEKLDYTLNNKRRVIRLVQQWATLYGDLLREDEVSMAFLEEFYVSVSDDTRTTAA-----------LKEQLPDLE-RAIKQISEDAKGQQKKHKVLLRQFSTGDERLQKRQAIRSSDELLFKVYCIDHTYTTIRVAVAASVKEVLSAVADKLG-SGDSLILVKISSAGEKVVLKPNEISVFTTLSVNGRLFACPRDQFDSLTPLPEQEGPSAGTMST-----FELMSSKDLAYQMTIHDWDLFSCVHELELIYHTFGRQNFKKTTANLDLFLRRFNEIQFWVVTEICLCPQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLSLTWEKLPSKFKKIYAEFENLMDPSRNHRAYRLTVAKLDPPIIPFTPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTLRTIRYCRSVPFNPDASLAGK-----NHQDVRNYVRQFNVIDNQRTLSQMSHRLEPRR 1023          

Query:  281 RTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSE-GNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNN-QTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFS--KHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            R+ ED+D I+  LK +K++   HP LLQQ+C    YE+L++ I +Y+ G    + Y V++GSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E+ ELL ++QK F+ +W K  ++                   M+   A   G P   N   +  P +T     +  I+ A   +  +   +L   P     +     + +Q  VG ++V W M+Q   ++SR  A+G+WQVLLEE +L  +   Y  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R+ ++ E I+ EL+HIKALSHLS+ VKR+L+  L++E HP  G V   QGSE   +W +     +++ I    VVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK +  S G       Q N    Y Y+VM+G PEK+++H LE  R+D + + A          D  L+ FIL +  F+ +  LC  L+  +   N+  +P+ G      ++E     L  K RV+  +  W  +      ED V  +F E     ++ + + + +L            EQ    E  A K+I + +K    KH++  +  +   ++L     I+  D   F V+        +R+ V ++V++++  VA       D+L L ++ S GE+++ +  ++ V   LSVNG+++    +++     L E+       + T     F+  S  +LA+ +T  DW LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K++ +  +L+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT+  DN++NFEKM+M A ++  + +CR+ P   + S + K     N  D++NYVR F  +DNQ+ L+Q+S  LE ++
Sbjct:   26 RSGEDVDIIFARLKEVKAFERFHPNLLQQICFCGYYENLEKGITLYRQGDIGTSWYAVLTGSLDV----KVSETNNH----QDAVVICTLGVGTAFGESI-LDNTPRH-----------ATIVTRENSELLRIEQKDFKTLWEKYRQY-------------------MAGFLAPPYGTPLIENQIPIR-PAKTITEVPSERILRAGKTLRNA---ILTRAPHMIRDRKYHLKTYRQCCVGTELVDWLMQQSSCVHSRTQAVGMWQVLLEEGVLNHVDQEYYFQDKYL-FYRFLDDEHEDAPMPTEEEKKESDEE----LQDTLLLLSQIGPDAHMRMILRKPPGQRSADDLEIIFEELIHIKALSHLSTTVKRELAGFLIFESHPKAGTVC-NQGSEFSKNWRVTCDFKINIIIT---VVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKILAGSQGSA-----QGNTQSPYKYTVMSGNPEKLLEHFLETMRLDPSLNDAT---------DTALDDFILMHCVFMPNSQLCPALMSQYPFSNHISSPSQG-----TEQEKLDYTLNNKRRVIRLVQQWATLYGDLLREDEVSMAFLEEFYVSVSDDTRTTAALK-----------EQLPDLE-RAIKQISEDAKGQQKKHKVLLRQFSTGDERLQKRQAIRSSDELLFKVYCIDHTYTTIRVAVAASVKEVLSAVADKLG-SGDSLILVKISSAGEKVVLKPNEISVFTTLSVNGRLFACPRDQFDSLTPLPEQEGPSAGTMST-----FELMSSKDLAYQMTIHDWDLFSCVHELELIYHTFGRQNFKKTTANLDLFLRRFNEIQFWVVTEICLCPQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLSLTWEKLPSKFKKIYAEFENLMDPSRNHRAYRLTVAKLDPPIIPFTPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTLRTIRYCRSVPFNPDASLAGK-----NHQDVRNYVRQFNVIDNQRTLSQMSHRLEPRR 996          

Query: 1310 ERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHI------KGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDF 1657
            ER+ E+ + I+  L  +KA       + +Q+     YE +   G  ++ QG  G SWY +L GS+DV +      +   V+C L     FG+ ++++N+PR A+I+ REN    L+I+++DF
Sbjct:   25 ERSGEDVDIIFARLKEVKAFERFHPNLLQQICFCGYYE-NLEKGITLYRQGDIGTSWYAVLTGSLDVKVSETNNHQDAVVICTLGVGTAFGE-SILDNTPRHATIVTRENS-ELLRIEQKDF 143          

Query:  233 SQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSE-GNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +  A+ I CLDK    R+ ED+D I+  LK +K++   HP LLQQ+C    YE+L++ I +Y+ G    + Y V++GSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E+ ELL ++QK F+ +W K  +++    L+    V++       I  AG +                      N  +  A   I     HL                + +Q  VG ++V W M+Q   ++SR  A+G+WQVLLEE +L  +   Y  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R+ ++ E I+ EL+HIKALSHLS+ VKR+L+  L++E HP  G V   QGSE   +W +     +++ I    VVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK +  S G       Q N    Y Y+VM+G PEK+++H LE  R+D               P+  L+ FIL +  F+ +  LC  L+  +   N+          I  +E     L  K RV+  +  W  +      ED V  +F E     ++ + + + +L  KE                       Q     +H++  +  +   ++L     I+  D   F V+        +R+ V ++V++++  VA       D+L L ++ S GE+++ +  ++ V   LSVNG+++    +++     L E+       + T     F+  S  +LA+ +T  DW LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K++ +  +L+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT+  DN++NFEKM+M A ++  + +CR+ P   + S + K     N  D++NYVR F  +DNQ+ L+Q+S  LE ++
Sbjct:   10 TSSAEWIACLDKRPLERSGEDVDIIFARLKEVKAFERFHPNLLQQICFCGYYENLEKGITLYRQGDIGTSWYAVLTGSLDV----KVSETNNH----QDAVVICTLGVGTAFGESI-LDNTPRH-----------ATIVTRENSELLRIEQKDFKTLWEKYRQYMAGF-LAPPYGVLETGSNDKRILRAGKTL--------------------RNAILTRAPHMIRDRKYHL---------------KTYRQCCVGTELVDWLMQQSSCVHSRTQAVGMWQVLLEEGVLNHVDQEYYFQDKYL-FYRFLDDEHEDAPMPTEEEKKESDEE----LQDTLLLLSQIGPDAHMRMILRKPPGQRSADDLEIIFEELIHIKALSHLSTTVKRELAGFLIFESHPKAGTVC-NQGSEFSKNWRVTCDFKINIIIT---VVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKILAGSQGSA-----QGNTQSPYKYTVMSGNPEKLLEHFLETMRLD---------------PNTALDDFILMHCVFMPNSQLCPALMSQYPFSNH----------ISSQEKLDYTLNNKRRVIRLVQQWATLYGDLLREDEVSMAFLEEFYVSVSDDTRTTAAL--KE-----------------------QLPDLERHKVLLRQFSTGDERLQKRQAIRSSDELLFKVYCIDHTYTTIRVAVAASVKEVLSAVADKLG-SGDSLILVKISSAGEKVVLKPNEISVFTTLSVNGRLFACPRDQFDSLTPLPEQEGPSAGTMST-----FELMSSKDLAYQMTIHDWDLFSCVHELELIYHTFGRQNFKKTTANLDLFLRRFNEIQFWVVTEICLCPQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLSLTWEKLPSKFKKIYAEFENLMDPSRNHRAYRLTVAKLDPPIIPFTPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTLRTIRYCRSVPFNPDASLAGK-----NHQDVRNYVRQFNVIDNQRTLSQMSHRLEPRR 956          

Query:  983 QQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFS--KHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +Q  VG ++V W M+Q   ++SR  A+G+WQVLLEE +L  +   Y  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R+ ++ E I+ EL+HIKALSHLS+ VKR+L+  L++E HP  G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK +  S G       Q N    Y Y+VM+G PEK+++H LE  R+D + + A          D  L+ FIL +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E     ++ + + + +           L EQ    E  A K+I + +K    KH++  +  +   ++L     I+  D   F V+        +R+ V ++V++++  VA       D+L L ++ S GE+++ +  ++ V   LSVNG+++    +++     L E+       + T     F+  S  +LA+ +T  DW LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K++ +  +L+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT+  DN++NFEKM+M A ++  + +CR+ P   + S + K     N  D++NYVR F  +DNQ+ L+Q+S  LE ++
Sbjct:   93 RQCCVGTELVDWLMQQSSCVHSRTQAVGMWQVLLEEGVLNHVDQEYYFQDKYL-FYRFLDDEHEDAPMPTEEEKKESDEE----LQDTLLLLSQIGPDAHMRMILRKPPGQRSADDLEIIFEELIHIKALSHLSTTVKRELAGFLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKILAGSQGSA-----QGNTQSPYKYTVMSGNPEKLLEHFLETMRLDPSLNDAT---------DTALDDFILMHCVFMPNSQLCPALMSHYH-----------AQPSQGTEQEKLDYTLNNKRRVIRLVQQWATLYGDLLREDEVSMAFLEEFYVSVSDDTRTTAA-----------LKEQLPDLE-RAIKQISEDAKGQQKKHKVLLRQFSTGDERLQKRQAIRSSDELLFKVYCIDHTYTTIRVAVAASVKEVLSAVADKLG-SGDSLILVKISSAGEKVVLKPNEISVFTTLSVNGRLFACPRDQFDSLTPLPEQEGPSAGTMST-----FELMSSKDLAYQMTIHDWDLFSCVHELELIYHTFGRQNFKKTTANLDLFLRRFNEIQFWVVTEICLCPQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLSLTWEKLPSKFKKIYAEFENLMDPSRNHRAYRLTVAKLDPPIIPFTPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTLRTIRYCRSVPFNPDASLAGK-----NHQDVRNYVRQFNVIDNQRTLSQMSHRLEPRR 870          

Query:  281 RTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVP----VRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSE-GNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNN-QTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFS--KHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIML--KDLTFINDANKTYFD 3238
            R+ ED+D I+  LK +K++   HP LLQQ+C    YE+L++ I +Y+ G    + Y V++GSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E+ ELL ++QK F+ +W K  +++    L+    V+         E+     L D  N    SVP    +R      N  +  A   I     HL                + +Q  VG ++V W M+Q   ++SR  A+G+WQVLLEE +L  +   Y  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R+ ++ E I+ EL+HIKALSHLS+ VKR+L+  L++E HP  G V   QGSE   +W +     +++ I    VVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK +  S G       Q N    Y Y+VM+G PEK+++H LE  R+D + + A          D  L+ FIL +  F+ +  LC  L+  +   N+  +P+ G      ++E     L  K RV+  +  W  +      ED V  +F E     ++ + + + +L            EQ    E  A K+I + +K    KH++  +  +   ++L     I+  D   F V+        +R+ V ++V++++  VA       D+L L ++ S GE+++ +  ++ V   LSVNG+++    +++     L E+       + T     F+  S  +LA+ +T  DW LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K++ +  +L+DP+RNH A+R  + K  PPIIPF  +++  K+  + N+  KT F+
Sbjct:   26 RSGEDVDIIFARLKEVKAFERFHPNLLQQICFCGYYENLEKGITLYRQGDIGTSWYAVLTGSLDV----KVSETNNH----QDAVVICTLGVGTAFGESI-LDNTPRH-----------ATIVTRENSELLRIEQKDFKTLWEKYRQYMAGF-LAPPYGVL---------ETGSNDRLSDKENMN--SVPSERILRAGKTLRNAILTRAPHMIRDRKYHL---------------KTYRQCCVGTELVDWLMQQSSCVHSRTQAVGMWQVLLEEGVLNHVDQEYYFQDKYL-FYRFLDDEHEDAPMPTEEEKKESDEE----LQDTLLLLSQIGPDAHMRMILRKPPGQRSADDLEIIFEELIHIKALSHLSTTVKRELAGFLIFESHPKAGTVC-NQGSEFSKNWRVTCDFKINIIIT---VVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKILAGSQGSA-----QGNTQSPYKYTVMSGNPEKLLEHFLETMRLDPSLNDAT---------DTALDDFILMHCVFMPNSQLCPALMSQYPFSNHISSPSQG-----TEQEKLDYTLNNKRRVIRLVQQWATLYGDLLREDEVSMAFLEEFYVSVSDDTRTTAALK-----------EQLPDLE-RAIKQISEDAKGQQKKHKVLLRQFSTGDERLQKRQAIRSSDELLFKVYCIDHTYTTIRVAVAASVKEVLSAVADKLG-SGDSLILVKISSAGEKVVLKPNEISVFTTLSVNGRLFACPRDQFDSLTPLPEQEGPSAGTMST-----FELMSSKDLAYQMTIHDWDLFSCVHELELIYHTFGRQNFKKTTANLDLFLRRFNEIQFWVVTEICLCPQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLSLTWEKLPSKFKKIYAEFENLMDPSRNHRAYRLTVAKLDPPIIPFTPLLIKGKEPAYRNNTAKTLFN 931          

Query:  242 AKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMD---NNVRAMSIESAGASGLPDDANSQNLS--VPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKS----STQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            A+ I CLDK    R+SED+D I+  LK +K++   HP LL+Q+CL   YE+L++ I +++ G    N Y V++GSL +    K+ E  +     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++Q+ F+ +W K  +++  L L+    VM+   NN R           +PD  N+  +   VP+R   P H    + +   I ++ K L +++ S     I  +     + +Q  VG ++V WM +Q   ++SR  A+G+WQVLLE+ +L  +      +D    +Y F+DD               +  +  ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G +++  NQ N      Y+VM+GTPEKI++H LE  R++ + + A          D +L  F++ +  F+ +  LC  L+ ++    +  P+ G      ++E     L  K RV+  +  W  +      ED V  +F E    +  ++     +   ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+       + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R    K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   13 AEWIACLDKRPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVSETSSH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTRESSELLRIEQEDFKALWEKYRQYMAGL-LAPPYGVMETGSNNDR-----------IPDKENTPLIEPHVPLR---PAHTITKVPSEK-ILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYL-FYRFLDD----EREDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAA--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEAT---------DSVLNDFVMMHCVFMPNTQLCPALVAHY----HAQPSQG-----TEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFY-VSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLG-SGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGT-----FELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 1010          

Query:  242 AKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            A+ I CLDK    R+SED+D I+  LK +K++   HP LL+Q+CL   YE+L++ I +++ G    N Y V++GSL +    K+ E  +     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++Q+ F+ +W K  +++  L L+    VM+                     S N  +P +   P     I+ A   +  +   +L   P     +     + +Q  VG ++V WM +Q   ++SR  A+G+WQVLLE+ +L  +      +D    +Y F+DD               +  +  ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G +++  NQ N      Y+VM+GTPEKI++H LE  R++ + + A          D +L  F++ +  F+ +  LC  L+ ++    +  P+ G      ++E     L  K RV+  +  W  +      ED V  +F E    +  ++     +   ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+       + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R    K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   13 AEWIACLDKRPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVSETSSH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTRESSELLRIEQEDFKALWEKYRQYMAGL-LAPPYGVMETG-------------------SNNDRIPDKENVPSEK--ILRAGKILRIA---ILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYL-FYRFLDD----EREDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAA--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEAT---------DSVLNDFVMMHCVFMPNTQLCPALVAHY----HAQPSQG-----TEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFY-VSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLG-SGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGT-----FELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 992          

Query:  812 LPDDANSQNLS--VPVRTTNPGHNPAIINAAFFIYKSSKHLLVSL----PSSFGGKIVSKSSTQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            +PD  N+  +   VP+R   P H    + +   I ++ K L +++    P     +     + +Q  VG ++V WM +Q   ++SR  A+G+WQVLLE+ +L  +      +D    +Y F+DD               +  +  ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G +++  NQ N      Y+VM+GTPEKI++H LE  R++ + + A          D +L  F++ +  F+ +  LC  L+ ++    +  P+ G      ++E     L  K RV+  +  W  +      ED V  +F E    +  ++     +   ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++ ++        G T   T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R    K  PP+IPF  +++KD+TF ++ NKT F DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   30 IPDKENTPLIEPHVPLR---PAHTITKVPSEK-ILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYL-FYRFLDD----EREDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAA--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEAT---------DSVLNDFVMMHCVFMPNTQLCPALVAHY----HAQPSQG-----TEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFY-VSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLG-SGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQF-DSLTPLPEQEGPT---TGTVGTFELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKT-FIDNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 866          

Query:  920 KHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQL-IKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLET----AINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDS-PGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDP---MLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTE-----IAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPP--IKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRI-TSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRAR---PM---------IFENSTSMKKDKLS-------NTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +HLL + P+    +       +    G ++V  +  L + ++SR  A+GI QVLL+E  L  +   +  +D  + +Y F               G         D+E     A+  L +  PDAL  + L K   +R  EE + I+ ELLHIKA++HLS+ VKR+L++VL++E H   G V+F QG +G SWYII KGSV+V   GKG+V  L   DDFG+LALVN++PRAA+IILREN+CHFL++DK+DFNRI++DVE  T+RL EHGK VL+ E+    + P R  +        G   Y+VM+GTPEKI++ LLE  R D++              DP    L  F+LT+  F+ S  L + LL +F +     P  G      ++EH   +  ++ +++  +  W  +       D V  SF + L ++++ + + SN LL +++        +  + E     ++   K      +  +Q     S+A + ++ D  P  I   D S  T+H          L V ++V++++  +A HE+       L ++ S G+ +  + +  GV  +L +N +++++  +E  E        +G T   +E+    D  S  +LA  LT  DW LF  IH  EL+  VLG      + T+NL+ F+R+F  +QYWV TE+C C     R  +++K IKLA+ L E KN++S FAV+ GL+NSA++RL  TWERL  K RKL+  L  LLDP+ NH  +R  L K  PP+IPF  ++LKD+TFI++ N T   +N+INFEKM+M A ++  + HCR+    P+         I E+S   +    S       +      YV+  K +DNQ++L++LS  LE
Sbjct:  106 RHLLATYPTLIRDRKYHLRLYRHCCSGRELVDGILALGLGVHSRSQAVGICQVLLDEGALCHVKHDWTFQDRDAQFYRF--------------PGPEPEPTGTQDVEEELVEAMALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRENNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERTSQGAGPSRPPT-------PGRNRYTVMSGTPEKILELLLEAMRPDSSAH------------DPTETFLSDFLLTHSVFMPSTQLFTALLHHF-HVEPADPAGG-----SEQEHSTYICNKRQQILRLVGRWVALYSPMLHSDPVATSFLQKLSDLVSRDARLSN-LLREQYPERR----RHHRLENGCGNVSPQTKARNAPVWLPNQEEPLPSSAGAIRVGDKVPYDICRPDHSVLTLH----------LPVTASVREVMAALA-HEDHWTKGQVLVKVNSAGDVVGLQPDARGVATSLGLNERLFVVDPQEVHE-LTPHPEQLGPTLGSSEM---LDLVSAKDLAGQLTDHDWNLFNRIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGSRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALTKLSPPVIPFMPLLLKDVTFIHEGNHTLV-ENLINFEKMRMMARAVRMLHHCRSHSTAPLSPLRSRVSHIHEDSQGSRISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELE 925          

Query:  920 KHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQL-IKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLET----AINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDS-PGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDP---MLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTE-----IAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPP--IKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRI-TSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRAR---PM---------IFENSTSMKKDKLS-------NTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +HLL + P+    +       +    G ++V  +  L + ++SR  A+GI QVLL+E  L  +   +  +D  + +Y F               G         D+E     A+  L +  PDAL  + L K   +R  EE + I+ ELLHIKA++HLS+ VKR+L++VL++E H   G V+F QG +G SWYII KGSV+V   GKG+V  L   DDFG+LALVN++PRAA+IILREN+CHFL++DK+DFNRI++DVE  T+RL EHGK VL+ E+    + P R  +        G   Y+VM+GTPEKI++ LLE  R D++              DP    L  F+LT+  F+ S  L + LL +F +     P  G      ++EH   +  ++ +++  +  W  +       D V  SF + L ++++ + + SN LL +++        +  + E     ++   K      +  +Q     S+A + ++ D  P  I   D S  T+H          L V ++V++++  +A HE+       L ++ S G+ +  + +  GV  +L +N +++++  +E  E        +G T   +E+    D  S  +LA  LT  DW LF  IH  EL+  VLG      + T+NL+ F+R+F  +QYWV TE+C C     R  +++K IKLA+ L E KN++S FAV+ GL+NSA++RL  TWERL  K RKL+  L  LLDP+ NH  +R  L K  PP+IPF  ++LKD+TFI++ N T   +N+INFEKM+M A ++  + HCR+    P+         I E+S   +    S       +      YV+  K +DNQ++L++LS  LE
Sbjct:   64 RHLLATYPTLIRDRKYHLRLYRHCCSGRELVDGILALGLGVHSRSQAVGICQVLLDEGALCHVKHDWTFQDRDAQFYRF--------------PGPEPEPTGTQDVEEELVEAMALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRENNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERTSQGAGPSRPPT-------PGRNRYTVMSGTPEKILELLLEAMRPDSSAH------------DPTETFLSDFLLTHSVFMPSTQLFTALLHHF-HVEPADPAGG-----SEQEHSTYICNKRQQILRLVGRWVALYSPMLHSDPVATSFLQKLSDLVSRDARLSN-LLREQYPERR----RHHRLENGCGNVSPQTKARNAPVWLPNQEEPLPSSAGAIRVGDKVPYDICRPDHSVLTLH----------LPVTASVREVMAALA-HEDHWTKGQVLVKVNSAGDVVGLQPDARGVATSLGLNERLFVVDPQEVHE-LTPHPEQLGPTLGSSEM---LDLVSAKDLAGQLTDHDWNLFNRIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGSRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALTKLSPPVIPFMPLLLKDVTFIHEGNHTLV-ENLINFEKMRMMARAVRMLHHCRSHSTAPLSPLRSRVSHIHEDSQGSRISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELE 883          

Query:  251 ILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMD---NNVRAMSIESAGASGLPDDANSQNLS--VPVRTTN-----PGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            I CLDK    R+SED+D I+  LK +K++   HP LL Q+CL   YE+L++ I +++ G    N Y V++GSL +    K+ E  +     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++QK F+ +W K  +++  L L+    VM+   NN R           +PD  N+  +   VP+R  N     P     I+ A   +  +   +L   P     +     + +Q  VG ++V WM Q    ++SR  A+G+WQVLLE+ +L  +   +  +D    +Y F+DD +                +    L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G ++S  NQ N      Y+VM+GTPEKI++H LE  R++   + A          D +L  FI+ +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED V  +F E    +  ++     + L ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+    +  + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R  + K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   16 IACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVSETSSH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTRESSELLRIEQKDFKALWEKYRQYMAGL-LAPPYGVMETGSNNDR-----------IPDKENTPLIEPHVPLRPANTITKVPSEK--ILRAGKILRNA---ILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEE----LQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAS--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEAT---------DSVLNDFIMMHCVFMPNTQLCPALVAHYH-----------AQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFY-VSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLG-SGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGT-----FELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 1010          

Query:  242 AKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMD---NNVRAMSIESAGASGLPDDANSQNLS--VPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKS----STQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            A+ I CLDK    R+SED+D I+  LK +K++   HP LL+Q+CL   YE+L++ I +++ G    N Y V++GSL +    K+ E  +     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++Q+ F+ +W K  +++  L L+    VM+   NN R           +PD  N+  +   VP+R   P H    + +   I ++ K L +++ S     I  +     + +Q  VG ++V WM +Q   ++SR  A+G+WQVLLE+ +L  +      +D    +Y F+DD               +  +  ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G +++  NQ N      Y+VM+GTPEKI++H LE  R++ + + A          D +L  F++ +  F+ +  LC  L+ ++    +  P+ G      ++E     L  K RV+  +  W  +      ED V  +F E    +  ++     +   ++   L  +++Q  +   A  K         KH++  +  N   ++     PI+G D   F V+        +R+ V ++V+++I  VA       + L + +M S GE+++ +  DV V   L++NG+++    E++     L E+       + T     F+  S  +LA+ +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K + +  SL+DP+RNH A+R    K  PP+IPF  +++KD+TF ++ NKT+  DN++NFEKM+M A +   V + R++P    N  + + +K  N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   13 AEWIACLDKRPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVSETSSH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTRESSELLRIEQEDFKALWEKYRQYMAGL-LAPPYGVMETGSNNDR-----------IPDKENTPLIEPHVPLR---PAHTITKVPSEK-ILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYL-FYRFLDD----EREDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV---PAGNRAA--NQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEAT---------DSVLNDFVMMHCVFMPNTQLCPALVAHY----HAQPSQG-----TEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFY-VSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQK---------KHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLG-SGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGT-----FELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFI-DNLVNFEKMRMIANTARTVRYYRSQPF---NPDAAQANK--NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 1010          

Query:  920 KHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQL-IKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDS-PGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDP---MLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLA--LNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPP--IKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRI-TSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRAR---PM---------IFENSTSMKKDKLS-------NTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +HLL + P+    +       +Q   G ++V  +  L + ++SR  A+GI QVLL+E  L  +   +  +D  + +Y F                 + +    ++L  A+  L +  PDAL  + L KS  +R  EE + I+ EL+HIKA++HLS+ VKR+L++VL++E H   G V+F QG +G SWYII KGSV+V  +GKG+V  L   DDFG+LALVN++PRAA+IILREN+CHFL++DK+DFNRI++DVE  T+RL EHGK VL+ E+    + P R  +        G   Y+VM+GTPEKI++ LLE  R D++              DP    L  F+LT+  F+    L + LL +F +     P  G      ++E    +  ++ +++  +  W  +       D V  SF + L ++++ + + SN LL +++     +  LE         +K       F  H+     S+A + ++ D  P  I   D S  T+H          L V ++V++++  +A HE+       L ++ S G+ +  + +  GV  +L +N +I+++  +E  E        +G T   +E+    D  S  +LA  LT  DW LF  IH  EL+  VLG      + T+NL+ F+R+F  +QYWV TE+C C     R  +++K IKLA+ L E KN++S FAV+ GL+NSA++RL  TWERL  K RKL+  L  LLDP+ NH  +R  L K  PP+IPF  ++LKD+TFI++ N T   +N+INFEKM+M A ++  + HCR+    P+         I E+S + +    S       +      YV+  K +DNQ++L++LS  LE
Sbjct:  106 RHLLATYPTLIRDRKYHLRLHRQCCSGRELVDGILALGLGVHSRSQAVGICQVLLDEGALCHVKHDWTFQDRDAQFYRFPGP----------EPQPAGTHDVEEELVEAMALLSQRGPDALLTVALRKSPGQRTDEELDLIFEELVHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTRGKGLVTTLHEGDDFGQLALVNDAPRAATIILRENNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERTSQGAGPSRPPT-------PGRNRYTVMSGTPEKILELLLEAMRPDSSAH------------DPTETFLSDFLLTHSVFMPCTQLFAALLHHF-HVEPSEPAGG-----SEQERSTYICNKRQQILRLVSRWVALYSPMLRSDPVATSFLQKLSDLVSRDTRLSN-LLREQYPERRRHHRLENGCGNVSPQTKARNAPVWFPNHE-EPLPSSAGAIRVGDKVPYDICRPDHSVLTLH----------LPVTASVREVMAALA-HEDHWTKGQVLVKVNSAGDVVGLQPDARGVATSLGLNERIFVVDPQEVHE-LTPHPEQLGPTLGSSEM---LDLVSAKDLAGQLTEHDWNLFNRIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALTKLSPPVIPFMPLLLKDMTFIHEGNHTLV-ENLINFEKMRMMARAVRMLHHCRSHSTAPLSPLRSRVSHIHEDSQASRISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELE 925          

Query:  920 KHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQL-IKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLET----AINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDS-PGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDP---MLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTE-----IAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPP--IKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIH-VYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRAR---PM---------IFENSTSMKKDKLS-------NTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +HLL + P+    +       +    G ++V  +  L + ++SR  A+GI QVLL+E  L  +   +  +D  + +Y F               G         D+E     A+  L +  PDAL  + L K   +R  EE + I+ ELLHIKA++HLS+ VKR+L++VL++E H   G V+F QG +G SWYII KGSV+V   GKG+V  L   DDFG+LALVN++PRAA+IILREN+CHFL++DK+DFNRI++DVE  T+RL EHGK VL+ E+    + P R  +        G   Y+VM+GTPEKI++ LLE  R D++              DP    L  F+LT+  F+ S  L + LL +F +     P  G      ++EH   +  ++ +++  +  W  +       D V  SF + L ++++ + + SN LL +++        +  + E     ++   K      +  +Q     S+A + ++ D  P  I   D S  T+H          L V ++V++++  +A HE+       L ++ S G+ +  + +  GV  +L +N +++++  +E  E        +G T   +E+    D  S  +LA  LT  DW LF  IH V E L  V         T+NL+ F+R+F  +QYWV TE+C C     R  +++K IKLA+ L E KN++S FAV+ GL+NSA++RL  TWERL  K RKL+  L  LLDP+ NH  +R  L K  PP+IPF  ++LKD+TFI++ N T   +N+INFEKM+M A ++  + HCR+    P+         I E+S   +    S       +      YV+  K +DNQ++L++LS  LE
Sbjct:  106 RHLLATYPTLIRDRKYHLRLYRHCCSGRELVDGILALGLGVHSRSQAVGICQVLLDEGALCHVKHDWTFQDRDAQFYRF--------------PGPEPEPTGTQDVEEELVEAMALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRENNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERTSQGAGPSRPPT-------PGRNRYTVMSGTPEKILELLLEAMRPDSSAH------------DPTETFLSDFLLTHSVFMPSTQLFTALLHHF-HVEPADPAGG-----SEQEHSTYICNKRQQILRLVGRWVALYSPMLHSDPVATSFLQKLSDLVSRDARLSN-LLREQYPERR----RHHRLENGCGNVSPQTKARNAPVWLPNQEEPLPSSAGAIRVGDKVPYDICRPDHSVLTLH----------LPVTASVREVMAALA-HEDHWTKGQVLVKVNSAGDVVGLQPDARGVATSLGLNERLFVVDPQEVHE-LTPHPEQLGPTLGSSEM---LDLVSAKDLAGQLTDHDWNLFNRIHQVQEHLRDV--------TTANLERFMRRFNELQYWVATELCLCPVPGSRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALTKLSPPVIPFMPLLLKDVTFIHEGNHTLV-ENLINFEKMRMMARAVRMLHHCRSHSTAPLSPLRSRVSHIHEDSQGSRISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELE 917          

Query:  920 KHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQL-IKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDS-PGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDP---MLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRS--KFSKHQIGSKTSNATSQQLVDIPP--IKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRI-TSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRAR---PM---------IFENS-----TSMKKDKLS--NTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +HLL + P+    +       +Q   G ++V  +  L + ++SR   +GI QVLL+E  L  +   +  +D  + +Y F                  ++ +  ++L  A+  L +  PDAL  + L K   +R  EE + I+ ELLHIKA++HLS+ VKR+L++VL++E H   G V+F QG +G SWYII KGSV+V   GKG+V  L   DDFG+LALVN++PRAA+IILRE++CHFL++DK+DFNRI++DVE  T+RL EHGK VL+ E+    + P R  +        G   Y+VM+GTPEKI++ LLE     + ++           DP    L  F+LT+  F+ S  LC+ LL +F    +  P  G      ++E    V  ++ +++  +  W  +       D V  SF + L +++  + + SN L  +      C   + +     AS ++  R+   +  +Q      ++ + Q+ D  P  I   D S  T          L+L V ++V++++  +A+ +        L ++ S G+ I  + +  GV  +L +N +++++  +E  E  +   + +G T    E     D  S  +LA  LT  DW LF +IH  EL+  VLG      + T+NL+ F+R+F  +QYWV TE+C C     R  +++K IKLA+ L E KN++S FAV+ GL+NSA++RL  TWERL  K RKL+  L  LLDP+ NH  +R  L K  PP+IPF  ++LKD+TFI++ N T   +N+INFEKM+M A +   + HCR+    P+         + E+S     ++  +  LS  +      YV+  K +DNQ++L++LS  LE
Sbjct:  106 RHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGP----------EPEPVRTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPT-------PGRNRYTVMSGTPEKILELLLEAMGPDSSAH-----------DPTETFLSDFLLTHRVFMPSAQLCAALLHHF----HVEPAGG-----SEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRC--HRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLT----------LQLPVTASVREVMAALAQEDGW-TKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHE-LIPHPDQLGPTVGSAE---GLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLV-ENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELE 922          

Query:  281 RTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFL-ALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            RT EDLD IY+ LK +K++   HP LLQQ+C    YEHL+  +++++ G    N Y V+SGSL +         +++  + +D +    ++ G AFG +  LN T  H             VVT E+CELL ++QK F+ +W +N++ +  + L+   S + N  +  +  +    G+P      N + P+ T  P    A              LL+  P     +     + ++ MVG +MV W+ Q    ++SR   +G+WQ LLEE ++V +    C      D Y+F   F+    G G    N    ++ ++    ++ L +  PDA+ RMIL K   ER  E+ E IY ELLHIKALSHLS+MVKR+L+SVL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAA+I+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK  T+   +  ++ +       Y YSVMAGTPEK+++HLLE RI   +  +          D  +E FILT+  F+ S+ LC  L+  +  Y        R T +++ + D   L  KTRVV F+  WC      FFED  I +F E  ++I +  +  + S+  KE + A++   + FQ+       +I +  + S H       +      VDI          F ++ +      L+L ++++V++II+       +  D+L LCE+KS+GER++F   DV V   LS+NG ++  A  E+ ++        G T       +I +  S  E+A+ LT +DW+LF  +H YEL++ V GR  FGRIT+NLD F+R+F  +QYWV +E+C  Q + +RV +++K+IK+A+   E++N++S FA+ MGL+N AV+RL  TWE+L +K +K+F D    +DP+RNH  +R  + K  PPI+PF  +++KD+TF ++ NKT+F D +INFEKM M A ++  +  CR++ +  E   S+K     N+ ++++Y R  K +DNQ+ LTQLS  LE ++
Sbjct:    9 RTGEDLDIIYSRLKDLKAFEKFHPLLLQQICYYSYYEHLERGVILFRQGDIGTNWYAVLSGSLDVN--------ISETGDAKDAVTLCTLSIGTAFGESI-LNDTPRH-----------ATVVTSENCELLRVEQKDFKVLWERNKQLMEGV-LAPSYSTLANAGKG-NTRNERKEGMP------NPAAPI-TAVPSEKLARAGQVLRTI-----LLMRAPHMIRDRKYHLRTYRRCMVGSEMVDWLIQHGGLVHSRNQGVGMWQALLEEGVIVHV----CHEHQFKDKYLFYR-FHDDDQGVGMTPSNIDRRESDENFHDVLSLLTQIGPDAMMRMILRKPPHERTLEDLEIIYEELLHIKALSHLSTMVKRELASVLVFESHAKAGTVLFNQGDEGKSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAATIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHNQDVLVLEKIPTNIQAQDGTIHSH------YKYSVMAGTPEKMLEHLLETRIGKTEDSS----------DTFMEDFILTHVIFMPSNHLCPTLMAQYPFYLAVL----RVT-MQEGDGD-YALCNKTRVVQFVQEWCCTIGEHFFEDKTIMAFLE--VSIQSTNRSVNQSISLKELISAVSEDAKIFQRFNCVIIAQIHRNVQCSDHLSPLTAEDGVVVAFVDI----------FKIYCADHTYSTLKLKMDTSVEEIIQHACNKLGLG-DDLVLCEVKSNGERVVFNENDVCVTTGLSINGHLF-TAPREHIDSLTPLVEQDGPTQ---GTWNILELLSSREVAYQLTLYDWELFNCVHEYELIYLVFGRQNFGRITANLDIFLRRFNEVQYWVASEMCLTQPVNKRVQLLRKLIKIAAYCKEMQNLNSFFAIAMGLSNIAVSRLSQTWEKLPNKFKKIFADFEMSMDPSRNHRVYRLSVAKMQPPIVPFMPLLMKDMTFTHEGNKTHF-DGLINFEKMHMIAQTLRTIRFCRSKSLDLEPPQSLK-----NSQEVKSYARTLKVIDNQRVLTQLSHKLEPRR 985          

Query:  242 AKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMD---NNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIIN--AAFFIYKSSKHL----LVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIK-INSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQI--VLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
             + I CLDK    R+SED+D I+  LK +K++   HP LLQQ+CL   YE+L++ I +++ G    N Y V++GSL +   D          N +D +    +  G AFG +  L++T  H             +VT+E  ELL ++QK F+ +W K  +++  L L+    VM+   NN R    +S  +S L   + + N + P+    P      I    +  I ++ K L    L   P     +     + +Q  VG ++V WM Q    ++SR  A+G+WQVLLEE +L  +   +  +D    +Y F+DD +                +    L+  + +L +  PDA  RMIL K   +R+ ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E HP  G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK      G + S  NQ N    + Y VM+GTPEKI++H LE  R++   + A          D +L  FI+ +  F+ +  LC  L+ ++            A P +  E +++   L  K RV+  +  W  +      ED    +F E    +  ++     + L ++   L  +++Q  +   A  K         KH++  +  N +  +     PI+G D   F V+        +R+ V S+V+++I  VA       + L + +M S GE+++ +  DV V   LSVNG+++    +++     L E+       + T     F+  S  +LA  +T +DW+LF  +H  EL++   GR  F + T+NLD F+R+F  IQ+WVVTE+C C  L +RV ++KK IK+A+   E KN++S FA++MGL+N AV+RL +TWE+L SK +K++ +  SL+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT F DN++NFEKM+M A ++  V  CR++    + + + K     N  D+++YVR    +DNQ+ L+Q+S  LE ++
Sbjct:   13 GEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLQQICLCGYYENLEKGITLFRQGDIGTNWYAVLTGSLDVKVSDTS--------NHQDAVTICTLGVGTAFGESI-LDNTPRH-----------ATIVTREYSELLRIEQKDFKALWEKYRQYMSGL-LTPPYGVMETGSNNDRMPDKDSMSSSALCQVSKNCNKTPPIEPHIPPRPTKTITQVPSEKILRAGKILRNTILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQSPCVHSRSQAVGMWQVLLEEGVLNHVDQEHYFQDKYL-FYRFLDDEHEDAPLPTEEEKKECDEE----LQDTMLFLSQIGPDAHMRMILRKPPGQRSVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKI---PAGNRIS--NQGNSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEAT---------DSVLNDFIMMHCVFMPNSQLCPALMAHYH-----------AQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFY-VSVSDDTRMIAALKEQLPELEKIVKQVSEEPKAPQK---------KHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLG-SGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGT-----FELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKT-FTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALTNK-----NHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRR 1025          

Query:  281 RTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLP---DDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKH-------LLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDD-LETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENL-LNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEI-----AASKKIGQRSKFSKHQIGSKTSNATSQQLVDIP-PIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKL 3358
            RT+EDLD I++ LK +K     HP+LLQQ+C    YE L++ I +++ G    N Y V++GSL ++  D     ++QD      +   ++  G +FG            KP+S+       VVT++  ELL ++ K F+ +W  +    R++  S    +   N + M       S LP   +D    N +  V   +   NPA     F   K +         L+ S P     +     + ++ MVG +M  W+  Q   + +R   +G+WQVLLEE +LV +   +  +D    Y    DD       G G + ++   + C++ L+  +  L K  PDA+ RMIL K G +R  EE E IY ELLHI ALSHLS MVKR+L+SV+++E HP  G V+F QG EG SWYIILKGSV+V I GKG+V  L+  DDFGKLALVN++PRAA+I+L+E++CHFL++DK+DFNRILRDVE NTVRL EHG+DVLL EK     P    S  +Q      Y YSVMAGTPEK+ ++LLE  ID   ++              L+ F+LTY  F++   LC       Q  NNQ           D+E    +L  K  VV F+  W  ++  AF E+  I  F + + LNI          L+N ++ A  C++  F  + I       S     + K +   I S+ S+  SQQ  +   PIK KD + F V+ +      LRL ++STV++II   A+ +    D+  LCE+KS GERI+F  ED+ +  +LS+NG++++   E       L E+         T  S+  +  S  ELA+H+T +DW+LF  IH YEL++ V G SKFGRIT+NLD F+R+F  +Q+WVVTE+    N+ +RV +++K+IKLAS   + +N+ S FA++MGL+N AV+RL  TWE+L  K +KLF++  +++DP+RNH  +R  + K  PPIIPF  +++KD+TF +D NKTYF DN++NFEKM M A ++  V +CR++P+  E+    K+ KL
Sbjct:   54 RTAEDLDVIHSKLKELKVLEKFHPFLLQQLCYYGFYECLEKGITLFRQGDVGTNWYTVLTGSLAVLTSDSTRPKVHQD-----GVMLCIVGPGTSFGEGILTG------KPHSVT------VVTKDTTELLRVELKDFKVLWEVS----RNIASSPLTVLSSRNKQQMESAVTPLSALPCLSEDMRKLNCNQFVEPGDTIPNPAAPITTFPSEKVAHAAHVLRTVLMTSAPYMIRDRKFHLRTYRRCMVGSEMTDWLLSQNTLVQTRQQGVGMWQVLLEEGVLVHVCHEHQFKDKYLFYRFTTDD------QGTGVTPSAADRKACEEQLQDTLLMLAKIGPDAMMRMILRKPGADRTFEEIEIIYEELLHISALSHLSCMVKRELASVIVFESHPKAGTVLFNQGDEGKSWYIILKGSVNVVIYGKGIVSTLQEGDDFGKLALVNDAPRAATIVLKEDNCHFLRVDKDDFNRILRDVEANTVRLKEHGQDVLLLEKIPVTVPTTGGSFHSQ------YKYSVMAGTPEKMFEYLLETLIDNKNTF--------------LQDFLLTYVIFMSDESLC-------QAINNQYLFIHNI--YLDQEAVDFILSHKKGVVQFVLEWYNVAGDAFLENPAITKFLKVMHLNIY---------LINLQYTA--CMVSIFLTSSIFVLYSTTSTGRPTKKKATHSLIISRKSSLKSQQGSEKKRPIKAKDENIFKVYCADHTYSTLRLPMDSTVKEII-IAARDKLCLGDDPVLCEVKSTGERIVFRDEDICITTSLSLNGRLFITPPEHLDALTPLPEQE-----GPSTGTSNTLEMMSTKELAYHMTCYDWELFSCIHEYELIYHVFGPSKFGRITANLDLFLRRFNEVQFWVVTEMLLVTNVSKRVQLLRKLIKLASHCKDFQNLHSFFAIVMGLSNIAVSRLSQTWEKLPGKLKKLFEEFETIMDPSRNHRVYRLTVAKMAPPIIPFMPLLMKDMTFTHDGNKTYF-DNLVNFEKMHMIAQTLRTVGYCRSQPLHSEDEGPDKQLKL 1025          

Query:  233 SQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIES--------AGASGLPDDANSQNLSVPVRTTNPGHNPA--IINAAFFIYKSSKHLLVS-LPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQS---FTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTE-IAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENF-LDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            S+ A+ I+CLDK    R+ ED+D I   L+ +K+  G HP LLQQ+CL   YE L++ I +++ G    + Y V+SGSL +         +++  + RD +    +  G AFG +  L++T  H             +VT+E  ELL ++QK F+ +W K    +  L L+    VMD+N      E            S  P+  +       + T +P   P+  I+ A     K  +H ++S +P     +     + +Q  VG ++V W M Q   ++SR+ A+G+WQVLLEE +L  +      +D    +Y F+DD               +  ++ ++L+  + +L +  PDAL RMIL K   ER  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F+QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE+DCHFL++DKEDFNRILRDVE NTVRL EHG+DVL+ EK ++ S   ++S+  Q +    + Y++M+GTPEKI++HLLE          +  D   T  D  L+ F+LT+  F+ +  LC +L     +Y+ Q   D     ++        L  K RV+  +  W      A   +H+ Q    F E  L  ++ + K            L  L +Q  + E I  S     RS   KH++  +  N   ++L    PIKG D   F V+        +R+ V S+V++++E VA       ++L L  + S GE+++F+  DV +   LS+NG+++    ++      L E+    L ++       F+  S  ++A+H+T++DW+LF  +H  EL++   GR    + T NLD F+++F  IQ+WV+TEVC C  L +RV ++KK IK+A+   E KN+++ FAV++GL++ AV+RL  TWE+L SK +K + +  +L+DP+RNH A+R  + K  PP+IPF  +M+KD+TF ++ NKT+  DN++NFEKM+M A ++  V + R++    ++  + K        D+  YVR    +DNQ+ LTQLS GLE ++
Sbjct:   11 SESAEWIICLDKRPAERSGEDVDIILARLRNVKALEGFHPRLLQQICLCGFYECLEKGITLFRQGDIGTSWYAVLSGSLDVK--------VSETSSYRDAVTICTLGTGTAFGESI-LDNTPRH-----------ATIVTREFSELLRIEQKEFRSLWEKFHHCMAGL-LAPPYGVMDSNGSDRMPEKENISSNSFVSVSKHPNKKSFPESPAKLHTKSPTQVPSEKILRAG----KILRHAILSRVPHMIRDRKYHLKTYRQCCVGTELVDWQMLQCSCVHSRIQAVGMWQVLLEEGVLNHVDGETVFQDKYL-FYRFLDD----EQEDALIPSEEERRESQEELQDTLLFLSQIGPDALMRMILRKPPSERTPDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHERAGTVLFHQGEEGTSWYIILKGSVNVVIYGKGVVCTLYEGDDFGKLALVNDAPRAASIVLREDDCHFLRVDKEDFNRILRDVEANTVRLKEHGQDVLVLEKSLSSS---RNSV--QGSSAAHHKYNIMSGTPEKILEHLLE---------MMRSDSQFTESDSALDDFVLTHCVFIPNSRLCPVL---SDHYHAQASQDSEMEKLD------YTLNNKRRVIRLVMKW-----AAVHGEHLQQQDMVFLEEFLVAVSEDAK-----------VLPALRDQLTELEKIIKSSADDARSSQRKHKVLLQHFNMVDEKLQKRQPIKGDDEILFKVYCCDHTYTTIRVPVASSVREVLEAVADKLG-SAEDLILVGLSSAGEKVVFKPNDVSIFSTLSINGRLFACQRDQLDVLVPLSEQEGPSLGSLAN-----FELMSSKDVAYHMTFYDWELFHCVHELELIYHTFGRQHVKKTTVNLDLFLQRFNEIQFWVITEVCLCSQLNKRVQLLKKFIKIAAHCKEYKNLNAFFAVILGLSHPAVSRLSQTWEKLPSKFKKFYGEFENLMDPSRNHRAYRLTVAKLAPPVIPFMPLMIKDMTFTHEGNKTFI-DNLVNFEKMRMIAKTVKTVRYFRSQTFSPDSPQAGKHHP-----DVWTYVRQLSVIDNQRTLTQLSHGLEPRR 1021          

Query:  233 SQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPA--IINAAFFIYKSSKHLLVS-LPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIG---QRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENF-LDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            S+ A+ I+CLDK    R+ ED+D I   LK +K+    HP LLQQ+CL   YE L++ I +++ G    + Y V+SGSL +         +++  + +D +    +  G AFG +  L++T  H             +VT+E  ELL ++QK F+ +W K    +  L L+    VM         ES+G+  +P+  N+ + S    + +P   P+  I+ A     K  +H ++S  P     +     + +Q  VG ++V W M Q   ++SR+ A+G+WQVLLEE +L  +      +D    +Y F+DD               +  ++ ++L+  +  L +  PDAL RMIL K   ER  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F+QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE+DCHFL++DKEDFNRILRDVE NTVRL EHG+DVL+ EK ++ +    SS          + Y++M+GTPEKI++HLLE          + LD   T  D  L+ F+LT+  F+ +  LC +L  ++           +A+   + E     L  K RV+  +  W  +      +  ++  F E  L  ++ + K            L  L +Q   TE+    KI     RS   KH++  +  N   ++L    PI G D   F V+        +R+ V S+V++++E VA       ++L L  + S GE+++F+  DV +   LS+NG+++     +      L E+    L ++       F+  S  ++A+H+T++DW+LF  +H  EL++   GR    + T NLD F+++F  IQ+WV+TEVC C  L +RV ++KK IK+A+   E KN+++ FAV+MGL++ AV+RL  TWE+L SK +K + +  +L+DP+RNH A+R  + K  PP+IPF  +M+KD+TF ++ NKT+  DN++NFEKM+M A ++  V +CR++    ++  + K        D+  YVR    +DNQ+ LTQLS GLE ++
Sbjct:   11 SESAEWIICLDKRPAERSGEDVDIILARLKNVKALERFHPRLLQQICLCGFYECLEKGITLFRQGDIGTSWYAVLSGSLEVK--------VSETSSYQDAVTICTLGTGTAFGESI-LDNTPRH-----------ATIVTREFSELLRIEQKEFRSLWEKYHPCMAGL-LAPPYGVM---------ESSGSDRMPEKENTSSNSFVSVSKHPNKVPSEKILRAG----KILRHAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWQMLQSSFVHSRIQAVGMWQVLLEEGVLNHVDGETVFQDKYL-FYRFLDD----EQEEALIPSEEEKRESQEELQDTLLNLSQIGPDALMRMILRKPPSERTPDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHERAGTVLFHQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDDCHFLRVDKEDFNRILRDVEANTVRLKEHGQDVLVLEKSLSRNSVHGSS-------AAHHKYNIMSGTPEKILEHLLE---------MMRLDSQFTESDSALDDFVLTHCVFIPNSQLCPVLSDHYH---------AQASQGSEMEKLDYTLNNKRRVIRLVMKWAAVHGEDLQQQDMV--FLEEFLVAVSEDAK-----------VLPALRDQL--TELEKVIKISADDARSSQRKHKVLLQHFNMVDEKLQKRQPINGADEILFKVYCCDHTYTTIRVPVASSVREVLEAVADKLG-SAEDLILVGLSSAGEKVVFKPNDVSIFSTLSINGRLFACQRAQLDVLMPLSEQEGPSLGSLPN-----FELMSSKDVAYHMTFYDWELFHCVHELELIYHTFGRQHVKKTTVNLDLFLQRFNEIQFWVITEVCLCSQLNKRVQLLKKFIKIAAHCKEYKNLNAFFAVIMGLSHPAVSRLSQTWEKLPSKFKKFYGEFENLMDPSRNHRAYRLTVAKLDPPVIPFMPLMIKDMTFTHEGNKTFI-DNLVNFEKMRMIAKTVKTVRYCRSQTFSPDSPQAGKHHP-----DVWTYVRQLSVIDNQRTLTQLSHGLEPRR 1002          

Query:  221 SIDVSQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPA--IINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEK-RITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTE--IAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            S   S  A+ I+CLDK    R++ED+D I   LK +K++   HP LLQQ+ L   YE L++ I +Y+ G    + Y V+SGSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++Q+ F+ +W K  + +  L L+    VM++           A  +PD  N  N S+   + +    P+  I+ A   +  +   +L   P     +     + +Q  VG ++V W M+Q   ++SR+ A+G+WQVLLEE +L  +      +D    +Y F+DD               ++ ++ ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK  I  S    SS +          Y+VM+GTPEKI++H LE          + LD   T  DP L+ F+L +  F+ +  LC LLL ++  + +Q           D+E     L  K RV+  +  W  I+     E+    +F +     ++ + +            +  L EQ  + E  +  + + G+ S+  KH++  +  +   ++L    PIK  D   F V+ S      +R+ V ++V++++  V        D+L L  + S G++++ +  +V +  +LS+NG+++  + E+      L E+    + ++     S F+  S  +LA+ LT +DW+LF  +H +EL++   GR  F + T+NLD F+R+F  IQ WVVTEVC C  L +RV ++KK IK+A+   E +N++S F+++MGL N AV+RL  TWE+L SK +K + +  +L+DP+RNH A+R  + K  PPIIPF  +++KD+TF ++ NKT+  D+++NFEKM+M A ++  + +CR++P   E   + K     N  D+++Y+R    +DNQ+ L+QLS  LE ++
Sbjct:   12 SAHSSASAEWIVCLDKRPAERSAEDVDIIMARLKSVKAFEKFHPTLLQQISLCGFYERLEKGITLYRQGDIGTSWYAVLSGSLDV----KVSETANH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTREFSELLRIEQREFRTLWEKYRQCMAGL-LAPPYGVMESG--------PSADRMPDKENLGNNSLGSVSKHLNKVPSEKILRAGKVLRSA---ILSQAPHMIRDRKFHLKTYRQCCVGTELVDWHMQQSSCVHSRVQAVGMWQVLLEEGVLNHVDQELNFQDKYL-FYRFLDD----EQEDAPLPSEEETKESNEELQDTLLLLSQMGPDAHMRMILRKQPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHEEDVLVLEKSNIRSSSHAGSSPLK---------YTVMSGTPEKILEHFLET---------MKLDSQFTESDPALDDFVLMHCVFIPNTQLCPLLLAHYHAHASQG---------SDQERLDYALNNKRRVIRLVLQWAAINTDHLQEEESSLAFLQEFYMAVSEDAR-----------LIPALKEQLPELEKILKHNSEDGKPSQ-KKHKVLLRQFSMGDEKLQKRQPIKSTDEILFKVYCSDHTYTTIRVLVSASVREVLSAVVDKLG-SRDDLLLVHLSSAGDKVVLKPSEVSIFSSLSINGRLFACSREQLDSLTPLPEQEGPSVGSM-----SNFELMSSKDLAYQLTMYDWELFNCVHEHELIYHTFGRQHFKKTTANLDLFLRRFNEIQLWVVTEVCLCSALSKRVQLLKKFIKIAAHCKEFRNLNSFFSIIMGLGNPAVSRLSQTWEKLPSKFKKFYGEFENLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTFI-DSLVNFEKMRMIANTVRIMRYCRSQPFTHEAPQATK-----NHQDVRSYIRQISVIDNQRTLSQLSHKLEPRR 1009          

Query:  266 KPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPA--IINAAFF----IYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCS------LLDPTRNHCAFRQYLKK 3154
            +P   R++ED+D I   LK +K++   HP LLQQ+ L   YE L++ I +Y+ G    + Y V+SGSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +VT+E  ELL ++Q+ F+ +W K  + +  L L+    VM++           A  +PD  N  N S+   + +    P+  I+ A       I   + H++             K S     VG ++V W M+Q   ++SR+ A+G+WQVLLEE +L  +      +D    +Y F+DD               ++ ++ ++L+  +  L +  PDA  RMIL K   +R  ++ E IY ELLHIKALSHLS+ VKR+L+ VL++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH +DVL+ EK        +SS    ++P     Y+VM+GTPEKI++H LE          + LD   T  DP L+ F+L +  F+ +  LC LLL  +  + +Q           D+E     L  K RV+  +  W  I+      DH+              E+++S + L + ++A++    +  +   A  +++ +  K  KH +G        ++L    PIK  D   F V+ S      +R+ V ++V++++  V        D+L L  + S G++++ +  +V +  +LS+NG+++  + E+      L E+    + ++     S F+  S  +LA+ LT +DW+LF  +H +EL++   GR  F + T+NLD F+R+F  IQ WVVTEVC C  L +RV ++KK IK+A+   E +N++S F+++MGL N AV+RL  TWER+ +   ++ +   S          T+NH   R Y+++
Sbjct:    3 QPDSERSAEDVDIIMARLKSVKAFEKFHPTLLQQISLCGFYERLEKGITLYRQGDIGTSWYAVLSGSLDV----KVSETANH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVTREFSELLRIEQREFRTLWEKYRQCMAGL-LAPPYGVMESG--------PSADRMPDKENLGNNSLGSVSKHLNKVPSEKILRAGKVLRSAILSQAPHMIRDRKFHLKTMYCKKKS---CCVGTELVDWHMQQSSCVHSRVQAVGMWQVLLEEGVLNHVDQELNFQDKYL-FYRFLDD----EQEDAPLPSEEETKESNEELQDTLLLLSQMGPDAHMRMILRKQPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHEEDVLVLEK-----SNIRSSSHAGSSP---LKYTVMSGTPEKILEHFLET---------MKLDSQFTESDPALDDFVLMHCVFIPNTQLCPLLLCTYHAHASQG---------SDQERLDYALNNKRRVIRLVLQWAAINT-----DHL-------------QEEESSLAFLQEFYMAVS----EDARLIPALKEQLPELEKILKHNMG-------DEKLQKRQPIKSTDEILFKVYCSDHTYTTIRVLVSASVREVLSAVVDKLG-SRDDLLLVHLSSAGDKVVLKPSEVSIFSSLSINGRLFACSREQLDSLTPLPEQEGPSVGSM-----SNFELMSSKDLAYQLTMYDWELFNCVHEHELIYHTFGRQHFKKTTANLDLFLRRFNEIQLWVVTEVCLCSALSKRVQLLKKFIKIAAHCKEFRNLNSFFSIIMGLGNPAVSRLSQTWERMIANTVRIMRYCRSQPFTHEAPQATKNHQDVRSYIRQ 881          

Query:  980 TQQVMVGEDMVSWMRQLIKIN----SRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMA------FEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKF-GRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARP------------MIFEN-----STSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            T Q   G+++V W   LIK+N    SR  A G+WQVL++E ILV         D  + +Y F++  +         S N K  +  D+L+  +  L++  PDAL  MIL K   +R+ E+ E IY ELLH+KA+ HLS+ V+++L++VL++E H   G  VF QG +G SWYII KGSV+V   GKG+V  L   DDFG+LALVN++PRAA+IILRE++CHFL++DK+DF RIL+DVE NTVRL EHGK VL+ EK    S G+               Y+VM+GTPEKI++HLLE  ++DTN          G+ P P +  F+LT   F+ S  LC  L    Q+Y+ + P++G      + E     L  K ++V  +  W  +      ED V   F E L   + A+ + S+ L  +        LE   +T    ++K    +             A  + L    PI+ +D   + +      +  L L V S+V+ I+  VA+    P D++ L +M S G R+  ++E   V  +L +N +++L         E  KE    E++ +             +     ++A  LT +DW+LF  +H  EL++ V GR+KF G  T+NL+ F+R+F  +QYWVVTE+C C++L +R  ++KK+IK+A+ L E KN++S FAV+ GL+NSAV RL  TW+R+ SK ++++     LLDP+RNH A+R  + K  PP IPF  ++LK +TFI++ NK Y  D+++NFEKM+M A ++  V  CR++P            M  E      STS     L +  ++++Y++N K +DNQK+LTQLS  +E
Sbjct:   77 TYQCCSGKELVDW---LIKLNDCFQSRSQAAGMWQVLVDEGILVH-KQELNFHDKDTQFYRFMETEFDLN-----PSTNEKDSKE-DELQEGLALLVQMGPDALLNMILRKPS-QRSSEDVEVIYEELLHVKAVGHLSTSVRKELAAVLVFESHAKAG-TVFSQGDKGTSWYIIWKGSVNVITHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFIRILKDVEANTVRLEEHGKVVLVLEK----SSGQ---------------YTVMSGTPEKILEHLLETIKLDTN----------GSEPIPCVSDFLLTQQVFMPSAQLCPAL----QHYHAE-PSEG-----SELEKAAYALNTKQKIVKLVGQWVALYGPLLKEDPVACQFLEKLREEVMADLRLSSMLKEQLRDRRKNRLENGCQTLTKLNQKFDWFA-------------AYEEPLGKCEPIRAQDKVLYEIFKPDHNTVTLMLPVNSSVKDILSAVAE----PGDHV-LVKMNSTG-RVQLKLEATAVSTSLGLNERLFLCTASQVEQLEPLKEQLGPEQSTI----------DTLEQMCSKDIASQLTNYDWELFTAMHEVELVYYVFGRNKFAGVTTANLERFVRRFNEVQYWVVTELCLCEDLMKRALMLKKLIKIAT-LKEQKNLNSFFAVMFGLSNSAVHRLYKTWDRIPSKTKRIYCAYERLLDPSRNHRAYRLAVAKLNPPYIPFMPLLLK-MTFIHEGNKNY-TDSLVNFEKMRMIAKTVKIVRGCRSQPYPSSPQKGLTERMFLEAPAIRISTSDPSLTLRSVANIRHYIQNLKVIDNQKKLTQLSRAIE 845          

Query:  251 ILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASG--LPDDANSQNLSVPVRTTNPGHNPA----IINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKE-NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERL 3064
            +LC+      R+ ED+D I   LK++K++   HP LLQQ+CL   YE+L++ I +Y+ G    + Y V+SGSL +         +++  N +D +    +  G AFG +  L++T  H             +V++E+ ELL ++Q+ F+ +W K  + +  L L+    VM+          +GAS   +PD  + ++ S  +   +  HN      ++ A   +  +   +L   P     +     + +Q  VG ++V W ++Q   ++SR  A+G+WQ LLEE IL  +      +D    +Y F+DD               +  +  ++L+  + +L +  PD+  RMIL K   +R  E+ E IY ELLHIKAL+HLS+ VKR+L+ VL++E H   G V+F QG EG SWYII KGSV+V I GKGVVC L   DDFGKLALVN++PRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH KDVL+ +K +  S        +  N    + Y+VMAGTPEKI++HLLE  R+D N +           PDP L+ F+L +  F+ +  LC  LL     Y  QT      +PI+                             FF  H  Q         L  + K  N  ++K       LL QF   E   +KK                            P++  D     V+ +      +R+ V +T +++   VA+      + L L  + +  E+ + +  DV V  +L VNG++++   E+      L E+         T   S F+  S  +LAF +T +DW+LF  +H YEL++   GR  + R T+NL+ F+R+F  +Q WVVTEV  C  L +RV ++KK IK+A+   E +N++S FA++MG+ N AV+RL  TWERL
Sbjct:   15 VLCVFLRPGERSGEDVDIILARLKVVKAFEKFHPSLLQQICLCGFYEYLEKGITLYRQGDIGTSWYAVLSGSLDVK--------VSETANYQDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVSRENSELLRIEQREFKTLWEKYRQCMAGL-LAPPYGVME----------SGASNDRMPDKDSLRSDSDALNFLSKNHNKVPSEKLLRAGKILRNA---ILARAPHMIRDRKYHLKTYRQCCVGTELVDWQLQQSSCVHSRAHAVGMWQALLEEGILNHVDQELNFQDKYL-FYRFLDD----EDEEAVLPSEDEKREAEEELQETLLFLSQIGPDSHMRMILRKPPGQRTPEDLEIIYDELLHIKALAHLSNTVKRELAGVLIFESHAKAGTVLFNQGEEGTSWYIIQKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDKDVLVLQKSLRPS--------SHGNVPAHFKYTVMAGTPEKILEHLLETMRLDINFA----------DPDPALDDFVLMHCVFMPNSQLCPALLA---QYPAQT-----CSPIK----------------------------FFFLGHFYQ-------KDLEVQGKQINKKIDKH----KVLLRQFSSGEERLAKK---------------------------QPMRSFDDILLKVYCADHTYTTIRVPVLATGREVTAAVAEKLG-STEELLLISLSASAEKQILKPNDVSVFQSLGVNGRMFVCTREQLDSLAPLPEQE-----GPSTGSMSSFELMSSKDLAFQMTQYDWELFSCVHEYELVYHTFGRQAYRRSTANLELFLRRFNQVQLWVVTEVSLCGTLSKRVQLLKKFIKIAAHCREFRNLNSFFAIIMGMCNPAVSRLTQTWERL 824          

Query: 1805 YSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAK 3454
            Y V++GTP KI++HLL + R+D ++         G   + +L+ F+LTY  F++++ LC  LL             G+   +  KE     L RK +V+H +  W  +      E+  ++ F + L   +  +          EF  L   L++FQK        + +R    ++ I  + +++ S++++              V+ S      +R+      Q+++ TVA+    PV+++ L      GE+ L +  D     +L++ G++ +  +++  E      +   L    T L  I    +  +++  LT  DW LF ++H  EL++    R      T  L+  +++   +Q WV++E+  C +L +RV ++KK IK+A+     +N++S FA++MGLN +AV+RL +TWE++  K +KLF +L  L DP+ NH A+R   +K  PP IPF  ++LKD+TFI++ NKT F DN++NFEK+ M A ++  + HC+              D+ +   DL+  V     +DNQ+ L +LS  LE +
Sbjct:   93 YVVVSGTPHKILEHLLSDLRLDEHQ---------GATEEMLLDDFLLTYLVFMSTNDLCQALL-------------GQYPSLPRKE----ALYRKRKVLHLVSQWSSLYKDFLREEEHVKLFMKTLYRYVLEDVY--------EFPTLEKDLKEFQK--------LLRRRHLKENGIQIRGAHSDSREVM------------CRVYVSSDSYLGIRVRTTIVAQELLHTVAQRMEKPVEDMVLVAQTYSGEKRLIQPHDCIFSESLTLPGRL-MACWKDLSEILPPLTDCPELAQRSTRLLGI----NTWDISVALTNLDWSLFNSVHEQELVYYTFSRQASSGHTVALEQLLQRCNEVQQWVMSEILLCPSLGKRVQLLKKFIKIAAHCKAQRNLNSSFAIIMGLNTAAVSRLNLTWEKVPGKFKKLFSELELLTDPSLNHKAYRDAFRKMKPPKIPFMPLLLKDITFIHEGNKT-FHDNLVNFEKLHMIADTVRLIRHCQT-------------DQ-TGGPDLRASVHYLHIIDNQQTLFELSHRLEPR 569          

Query: 2732 ELAFHLTYFDWQLFKNIHVYEL---LFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTP--PPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVL 3298
            E+A  ++  D+ LF+ I   E    LFK+  RS+ G  T  L  F        +WV +EV       +RV ++K  IK+A    E KN +S FA++ GL++S+VARL  TWE+L +K+  L+++L  L DP+RN   +R  L      PP+IP F ++ KDLTF+++ N +   D M+NFEK++M A  + QV+
Sbjct:    2 EVAAQVSMGDFDLFRTIEPTEYVDDLFKL--RSRTG--TRALKLFEGALNQETFWVASEVLAEPGQIKRVKVLKHFIKIALHCRECKNFNSMFAIISGLSHSSVARLNGTWEKLPTKYESLYRELQDLFDPSRNMAKYRNVLSSQSLQPPLIPLFPVVKKDLTFLHEGNDSRV-DGMVNFEKLRMIAKEVRQVV 190          

Query: 2561 LFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYEL---LFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTP--PPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQV 3295
            L E   +   Y L  N +   +  +E+ +  L E + + L  + T            E+A  ++  D+Q+F++I   E    LF++ G +       +L AF        +WV +EV +   L +RV ++K  +K+A    + +N +S FA++ GL++S+V RL+  W++L SK+ KLF DL  L DP+RN   +R  L      PPIIP F ++ KDLTF++D N +   + ++NFEK++M A  +  V
Sbjct:  626 LAESIQLNARYYLKNNSQTEPLCSDEHAQELLKE-SQISLLQLSTL-----------EVATQISIRDFQIFRSIEPTEYVANLFRLGGAAA----CEHLQAFEETLNRETFWVPSEVLRETGLLKRVKLIKHYLKIALNCRDSRNFNSMFAIISGLSHSSVMRLRSAWDKLPSKYEKLFSDLQDLFDPSRNMAKYRNLLSSPSLQPPIIPLFPVVKKDLTFLHDGNDSRV-EGLVNFEKLRMIAKEVRHV 858          

Query: 1382 SMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGL 1975
            S ++R+L + +++ +    G VV   G E +SW +IL GSV++  +  G    L   + FG    +        +  + +DC F+ I ++D+ RIL  VE N  ++ E G+ V++ E R  D  G +              + V+ GTPE++I+HL+E     + +Y              +E F+LTY  F   HGL
Sbjct:  102 SFLRRELCASMVFAVVEKAGTVVLRDGEELDSWCVILNGSVEIS-RADGRTETLCMGNCFGVSPSMEKELMTGVMKTKVDDCQFVCIAQKDYCRILNKVERNMQKVEEEGEIVMVKEHRELDRTGTRKG------------HIVIKGTPERLINHLVEEHSVVDPTY--------------VEDFLLTYRTF-QPHGL 271          

Query: 2735 LAFHLTYFDWQLFKNIHVYELLFKVLGRS--KFGR-ITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVN-----------------IVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPP------------------------IIPFFAIMLKDLTFINDANKTYFDDNMINFEK 3262
            +A  LT  D +LFK +  +  L  V  R   K  R +  ++ A I QF  +   V   V +C + Q                     +V+  I +A     LKN SS  A+L  L  + + RL+ TW  +S +    F +L  +     NH   R+ L K                             IP+    L DLT ++ A   Y +  +INFEK
Sbjct:  340 VARQLTLRDAELFKKVAPHHCLGCVWSRRDRKGNRHLAPSVRATIAQFNAVAACVACTVLRCLSGQAAAGHGAPGTGARHAAAQRARVVEHWIAVAQECRMLKNFSSLRAILSALQTNPIHRLKKTWCCVSREKIVAFAELSEIFSDENNHFTSRELLMKEGTSKFASLDSNGKESQKRTFKAGLMQGTIPYLGTFLTDLTMLDTALPDYVEGGLINFEK 559          

Query: 2840 SNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCS--LLDPTRNHCAFRQYLKKTPPPIIP---FFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQ 3430
             +L  F+    NI  WV  E+  C +++ ++ ++ K + +A   S L+N +S   +L GL N  V +L + W  L SK   + ++L +  +   + + C       + P P IP    F++ ++ L    +       + M  + K++  A ++HQ+   ++R         +K       + L+  +  F+ +D Q   +Q
Sbjct:  422 GSLWKFLDHSANISTWVSAEILSCDSIKTQLAVLSKFLHVAKTCSSLRNFASSMQILNGLENFTVRQLPV-WRSLPSKAMAIMEELVAVKVFLKSDSECLLEADTSR-PKPTIPCPHLFSMHVQQL----EVGGFTMANRMYKWPKLRSLARTVHQIAAFQSRTYALAPDEELK-------VQLRARICRFRGVDLQALASQ 610          

Query: 1283 RMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVL--MYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGV---VCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRIL 1669
            R+I  K+ ++RN+     +     HI    +L    + Q+S VL  M+E     G+ V  QG++G+++Y+I +G  D+++    V   V        FG+LAL+ N+ RAA+II   ++     +D+  F RI+
Sbjct:  129 RVIHPKTDEQRNR-----LQEACKHILIFKNLD---QEQMSQVLDAMFEKTVETGEHVIDQGADGDNFYVIERGMYDIYVTTNDVSRCVGAYNNRGSFGELALMYNTSRAATIIA-TSEGALWGLDRLTFRRII 253          

Query: 2738 AFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRI--TSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKK-TPPPIIPFFAIMLKDLTFINDANKTYFDD--NMINFEKMQMYAASMHQVL 3298
            A  LT  +  L+  I ++E L +  G +K+  +  + N+  FI     +  +V   + +  +++ R  + +  + +A    EL N SS  A++  L +S + RL+ TW+ +S++ + L ++L +L+D  RN   +R+ L+  T    +PFF + L DLTF    N  +  +  N+INF K    A  + +++
Sbjct: 1310 ATQLTVLEHDLYLRITMFECLDRAWG-TKYCNMGGSPNITKFIANANTLTNFVSHTIVKQADVKTRSKLTQYFVTVAQHCKELNNFSSMTAIVSALYSSPIYRLKKTWDLVSTESKDLLKNLNNLMDSKRNFVKYRELLRSVTDVACVPFFGVYLSDLTFTFVGNPDFLHNSTNIINFSKRTKIANIVEEII 1500          

Query: 1283 RMILHKSGKERNKEEFEFIYGELLH-IKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRIL 1669
            +++L  S K+R       +Y +LL  +  L  L++  + +L+  L  +I+   G+ +  +G +G ++Y+I  G+VDV  KG+GV+ +L+ +D FG++AL+N+ PR A++   +       + K  F R+L
Sbjct:  280 KILLGSSFKKR------LMYDDLLKSMPVLKSLTTYDRAKLADALDTKIY-QPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLPRQATVTATKR-TKVATLGKSGFQRLL 401          

Query: 1307 KERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRIL 1669
            KE+++++ + +   + +    + L S  KR + + L  +  P  G  +  QG +G+ +Y++ KG+VD ++    V         FG+LAL+ NSPRAA+++   +DC    +D+  F +IL
Sbjct:  165 KEKSEQQLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEKSVPK-GATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSS-GPGSSFGELALMYNSPRAATVVA-TSDCLLWALDRLTFRKIL 282          

Query: 2978 LKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKK---TPPPIIPFFAIMLKDLTFINDANKTYF-DDNMINFEK 3262
            L+N++S  +++  L N ++ RL +    +  K   LFQ L  ++ P  N+  +R+ +K    +  P +PF +++++D+TFI D N T+  D N +N +K
Sbjct:  485 LRNLNSLASIITSLQNHSIERLSLP---IDVKSDHLFQRLKVVVHPNNNYNVYRRTIKHIFHSQLPCVPFTSLLIRDITFIRDGNDTFTKDGNNVNMQK 580          

Query: 2840 SNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPI--IPFFAIMLKDLTFINDANKTYFDDNMINFEK 3262
            S +D  I +F     W+++E+   ++ + + N++++ I +A      +N ++   +++ L++S V +    W  +       +++L  +    RN+   R  L    P +  +PF  + L DL+   +      +D ++N+ K
Sbjct: 1244 SGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNK 1386          

Query: 2303 QRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            QR   S       T++    +   + PI+  D  TF V+ +      +R+    T Q I++T AK   +  D+  LCE+KS GER++F+  ++ V+  +S+N K+++ A +E+ ++        G     T L  +  S    E+A++LT ++++LF+  ++YE +++   R KFG+I++NLD  + +F  + YWV+TE+C    L +RV ++KK IK+AS   + KN++S FA++M LN +A++RL  TWE++ +K++KL+++L ++LDP+ NH  +R  + K  PP+IPF  +++KD+T IN  NKT+ ++ ++NFEKM+M   S+  V +CR+ P      +S+K        ++ +YVRN + +DN K LTQLS  LE
Sbjct:  594 QRRTMSFSSRRGGTADLKQPRRSKMTPIEKDDYVTFRVYCADHTYSTVRMRYGDTAQMIVDT-AKERLLLGDDCVLCEVKSSGERLVFQGNEISVITRISINSKLFI-APKEHIDSLTPLMEQEG-PECGTRLIEVISSR---EIAYYLTQYEYELFERCNIYEFIYQSFDREKFGQISANLDICLSRFNEVHYWVITEICLATQLSKRVFLLKKFIKIASYCKDYKNLNSAFAIIMALNCAAISRLTQTWEKIPNKYKKLYRELDAILDPSGNHRVYRLVVAKMKPPVIPFMVLIMKDITIINYGNKTFVNE-LVNFEKMRMITISLRLVEYCRSAPFDTPAPSSLKIPS-----EVPSYVRNLQVIDNGKTLTQLSYRLE 963          

Query:  335 YSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWM----RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRV 1903
            +  +HP++++Q+C    YE L+   V+Y+      N Y +++GS+ I         ++Q   + D +    +  G  FG +    S              +   +T + CELL ++ +  + I+ +N ++L  + L  +        +  ++E   A G     ++  L + ++ +       ++NAA  ++     ++ S P  F  +  +  +      G + V W+    RQ   ++SR  A+ ++Q LLEE         + L      Y    D  Y         +  +    T   + TA +  +          ++      R++E+ + IY ELL IK+LS++SS VK+++++ ++ E     G V+F QG EG+SWYIILKGSV+V + GKG+VC+L T DDFG+L+LVNN+PRAASI   E++CHFL++ KE F+ IL+DVE +++ L EHG DVL+ E+     P  +     + +      Y+VMAGT  K++D+LL+  I TNK    I++ V
Sbjct:   15 FKKVHPHVVRQICFYAYYEDLEPGTVLYRQDAKGLNWYAILTGSVNIC--------VSQTSKIEDAVTLCCLGPGSTFGESVLDGSPR------------TATAITNDYCELLCVNGEYLKTIFQQNRRYLVGIELPGE--------QCNTVEVTEADG----ESTLKLELQLKLSQ-----IMLNAAVVLHNK---MVKSAPHLFKERSCNSGTFPDCFAGSEAVDWLLDSSRQ---VHSRFHAVSVFQALLEEG-----RDHHNLDQRDHHYRNQCDHHYRDQRDHITVTSVTIITVTSVTIITATSVTIITVTSVTIIGVISVPNA-RSQEDVDTIYEELLRIKSLSYISSTVKKEMAAAVVLESCEHKGTVLFNQGDEGDSWYIILKGSVNVVVLGKGIVCQLHTWDDFGRLSLVNNAPRAASIETCEDNCHFLRVSKETFDNILKDVESSSLVLKEHGSDVLVLEEFKDRVPVNEKGQFKEKS-----YYAVMAGTASKMVDYLLQ--IPTNKETEKIVNNV 485          

Query: 2519 NLCLCEMKSDGERILFEMEDVGVMYNL----SVNGKIYLMAFEEYKE-------NFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFG-RITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYL--KKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARP 3316
            N  LCE+  +   ++ +      + NL    S+N + YL    E  +       + L +  HV L  +KT+           E+A HLT  D++LF+ I   E ++ V    +FG   + NL  F        +WVVTE+C   N+ +R+ ++K  IK+A    + KNI+S FA++ GL ++AV RL+ TWE+L +++ K+++DL +L+DP+R+   +R  L  +   PP+IPFF ++ +DLT I   NK+   D +INFEK++M A  + QV  C + P
Sbjct:  495 NYSLCEVTVEESGLVRQRRQPDSLANLADRISLNSRYYLKNNNETAQLLQGDATHDLGKECHVTLLQLKTQ-----------EVARHLTLQDFELFRAIDPREYIYDVW---EFGPEFSPNLAKFEETVNRETFWVVTEICGESNVVKRMKLIKHFIKIAKYCKDCKNINSAFAIISGLGHTAVKRLKNTWEKLPNRYYKMYEDLENLMDPSRSMFKYRSLLNSEHVNPPLIPFFPVIKRDLTLIYLNNKSVV-DGLINFEKLRMIAREVRQVSKCHSMP 759          

Query: 1376 LSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDP-MLETFILTYFAFLTS-HGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEK 2203
            ++  V+R L +V+++ +      +V   G E +SW +IL GSV + ++ +  +  L   D FG    +        +  R NDC F+ I + D+ RIL   E N   + E G+ V++ E R TD   R+  +             V+     K+I HL+E+       ++VI        DP  +E F+LT+  F      +C  LL +F               +ED   D++     TRV   +  W       F  DHV++ + +   + L  +K
Sbjct:    1 MTQNVRRSLCAVMVFAVVEKADAIVMKDGEELDSWCVILNGSVIIEVENEPPI-ELHLGDSFGVEPSLKKMYHHGLMRTRVNDCQFVCIAQSDYYRILTQGESNIQVIEEDGEVVMVTEHRSTDGGNRQGQV-------------VIKAKSGKLITHLVED-------HSVI--------DPTFVEDFLLTFKTFFDQPTKICGKLLNWF---------------LEDDLRDKV-----TRV---MLLWVNNHYNDFEGDHVMEDYLQAFESALEVQK 226          

Query: 2687 IKTELSSIFDSTSI--DELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRI--TSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFIN 3214
            IK   + +FD T +  D  A  LTY D  +FK+I   E  F   G +K  +   + N+ A  ++F ++ +WVV E+   + L+ RV ++   I++A RL E+ N+ S  AV+ GL ++ V RL  TWE+LS +   +F+ L  LL   +N    R +L  T  P IP   + L DL +I+
Sbjct:   50 IKNYDAVVFDITKVTPDNFARQLTYMDLAVFKSIQPEE--FSSCGWTKKNKSVQSPNVVALTKRFNHVSFWVVREILNAKKLKTRVAVMSHFIRIAKRLYEMNNLHSLKAVIAGLQSAPVYRLNQTWEQLSRRDHTIFEKLEDLLSEDQNRKRLRDHLNSTRLPCIPHLGMYLTDLMYID 227          

Query: 2837 TSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFR-----QYLKKTPPP--IIPFFAIMLKDLTFINDANKTYFDDNMINFEKM 3265
            TS+L+A++  F  + Y V TE+C   N + R  ++   I++A+   +  N +S  A++ G+N S VARL+ TW ++  K+RK F  L   ++P  N  A+R      +L+K+     +IPFF + +KD+ F+N+       +  INFEK 
Sbjct:  207 TSSLEAYVEWFNRLGYLVATEICLGHNKKVRAKVIDYFIEVATDCYDRGNFNSAMAIIAGINMSPVARLKKTWSKV--KNRK-FDRLEREMNPASNFAAYRASFKAAHLRKSDKNEYVIPFFGLFIKDVYFLNEGYSNRHSNGYINFEKF 353          

Query: 2711 FDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVR-NFKCLDNQKQLTQLSLGLEAKQLSS 3466
            F     +E+A  LTY ++++ + I   +  +K    +     T+ L+ ++  F  +  W+   V    + + R   ++K  K+A  L EL+N +   AV  GLNNS ++RL  T E +S   ++    L   L    N+  +R+ L       IP   I LKDL   + A     +D +IN  K+   A  + + + C+  P +           ++  ++L N +R + +   ++ +L +LSL  E + ++S
Sbjct:    6 FQDQQPEEIAEQLTYLEFRMLRRIPFSD--WKAYSLTSKLENTTYLERYVSMFNGLSKWIQAMVLNHTSAEDRAKCIEKFQKVAQSLKELQNFNGLLAVTGGLNNSVLSRLLQTREYVSKDCKEYMNLLTEFLSSENNYATYRKRLSCCAGFYIPILRIQLKDLIATHTALSDTVNDKLINVHKLVTLAGIISKSIVCQTTPPL-----------VTPNMELLNMLRVSLQPRLSEDELYELSLAREPRTMNS 245          

Query:  242 AKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMD---NNVRAM---SIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQ 3457
            A+ I CLDK    R+ ED+D I   L+ +K++    P LL Q+C    YE L++ I +++ G    + Y V+SGSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +V++E  ELL ++Q+ F+ +W K  + L  L L+     M+   NN R     ++ S   S   +   S+ L    R      N  +  A   I     HL                + +Q  VG ++V W+  Q   + +R  A+G+WQVLLEE +L  +      +D    +Y F+DD               +  ++ ++L   I +L +  PDAL RMIL KS  +R  ++ E IY ELLHIKAL+HLS+ VKR+L+SV+++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALV +SPRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH + VL+ EK    SP R S+L       G   Y+V++GTPEKI++H LE         A+ LD     PDP ++ F+L +  F+ +  LC LL+ +   Y+  +P      P  ++E  +  L  K RV+     W         E+    SF E L   ++    +S  L   + LA++  LE+  K          + +K SK +   +  +   ++L    PIK +D     V+ S      +R+ V +T +++I  V        D L L  + S GE+ + +  DV V   LS+NG+++       ++       H           S F+  S  +LA+ +T FDW+LF  +H +ELL+   GR  F R T+NLD F+R+F  +  WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MG++N AV+RL  TWE+L +K +K + +  S++DP+RNH  +R  + K  PPIIPF  ++LKD+TF ++ NKT+  DNM+NFEKM++ A ++ QV HCR++P    N    + +K  N  +++ YVR    +DNQ+ LTQLS  LE ++
Sbjct:   20 AEWICCLDKRPSERSGEDVDIILTRLREVKAFQRFPPPLLLQICACAFYECLEKGITLFRQGDIGTSWYAVLSGSLDV----KVSETANH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVSRETSELLRIEQREFKTLWEKYRQSLAGL-LAPPYGAMESGSNNDRLADKDNMNSESGSKAHNKIPSEKLQ---RAGKVLRNAILSRAPHMIRDRKYHL---------------KTYRQCCVGTELVDWLVMQSACVLTRSHAVGMWQVLLEEGVLNHVDQDLGFQDKYL-FYRFLDD----EDEDTPLPSEEEKRESEEELPETILFLAQIGPDALLRMILRKSPGQRTGDDLEIIYDELLHIKALAHLSNTVKRELASVVIFESHAKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVTDSPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHEQSVLVLEK----SP-RASTL-------GGIKYTVISGTPEKILEHFLE---------AMRLDIHHNEPDPAVDDFVLMHCVFMPNSQLCPLLMAH---YHAASP------PGSEQERLEYALNCKRRVLILALRWVNAHTYLLQEEPAAISFLEELYGSVS---NDSRILRGLKDLAVD--LEKVVKLH-------SEEAKSSKRKTLIRQFSNGEERLQKKQPIKNQDDILLKVYCSDHTYTTIRIAVAATGREVISAVTDKLGT-ADELLLIHLSSAGEKQILKPNDVSVFSTLSINGRLFACP----RDQLSGLTPHPDQEGPSAGSMSTFELMSSKDLAYQMTMFDWELFSCVHEHELLYHTFGRQSFRRTTANLDLFLRRFNQVMLWVVTEVCLCNQLSKRVQLLKKFIKIAAHCREFKNLNSFFAIIMGMSNPAVSRLSQTWEKLPTKFKKFYAEFESMMDPSRNHRTYRITVTKLEPPIIPFMPLLLKDMTFTHEGNKTFI-DNMVNFEKMRIIANTIRQVRHCRSQPF---NPDICQPNK--NQAEVRGYVRKLCVIDNQRALTQLSYRLEPRR 1001          

Query:  242 AKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSS---------KHRKLFQDLCSLLDPTRNHCAFRQYLKK 3154
            A+ I CLDK    R+ ED+D I   L+ +K++    P LL Q+C    YE L++ I +++ G    + Y V+SGSL +    K+ E  N     +D +    +  G AFG +  L++T  H             +V++E  ELL ++Q+ F+ +W K  + L  L        +     AM   S   S +     S+ L    R      N  +  A   I     HL                + +Q  VG ++V W+  Q   + +R  A+G+WQVLLEE +L  +      +D    +Y F+DD               +  ++ ++L   I +L +  PDAL RMIL KS  +R  ++ E IY ELLHIKAL+HLS+ VKR+L+SV+++E H   G V+F QG EG SWYIILKGSV+V I GKGVVC L   DDFGKLALV +SPRAASI+LRE++CHFL++DKEDFNRILRDVE NTVRL EH + VL+ EK    SP R S+L       G   Y+V++GTPEKI++H LE         A+ LD     PDP ++ F+L +  F+ +  L    LV    Y+  +P      P  ++E  +  L  K RV+                             IL     N+++ L +E  A    LE+            G  S  S+   G K         VD+  +         V+ S      +R+ V +T +++I  V        D L L  + S GE+ + +  DV V   LS+NG+++       ++       H           S F+  S  +LA+ +T FDW+LF  +H +ELL+   GR  F R T+NLD F+R+F  +  WVVTEVC C  L +RV ++KK IK+A+   E KN++S FA++MG++N AV+RL  TWER+ +         + +    D+C    P +N    R Y++K
Sbjct:   15 AEWICCLDKRPSERSGEDVDIILTRLREVKAFQRFPPPLLLQICACAFYECLEKGITLFRQGDIGTSWYAVLSGSLDV----KVSETANH----QDAVTICTLGIGTAFGESI-LDNTPRH-----------ATIVSRETSELLRIEQREFKTLWEKYRQSLAGL--------LAPPYGAMESGSNNDSDVTKQIPSEKLQ---RAGKVLRNAILSRAPHMIRDRKYHL---------------KTYRQCCVGTELVDWLVMQSACVLTRSHAVGMWQVLLEEGVLNHVDQDLGFQDKYL-FYRFLDD----EDEDTPLPSEEEKRESEEELPETILFLAQIGPDALLRMILRKSPGQRTGDDLEIIYDELLHIKALAHLSNTVKRELASVVIFESHAKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVTDSPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHEQSVLVLEK----SP-RASTL-------GGIKYTVISGTPEKILEHFLE---------AMRLDIHHNEPDPAVDDFVLMHCVFMPNSQLFIFNLVC--TYHAASP------PGSEQERLEYALNCKRRVL-----------------------------ILALRWVNAHTYLLQEEPAAISFLEEL----------YGSVSNDSRILRGLK------DLAVDLEKV---------VYCSDHTYTTIRIAVAATGREVISAVTDKLGT-ADELLLIHLSSAGEKQILKPNDVSVFSTLSINGRLFACP----RDQLSGLTPHPDQEGPSAGSMSTFELMSSKDLAYQMTMFDWELFSCVHEHELLYHTFGRQSFRRTTANLDLFLRRFNQVMLWVVTEVCLCNQLSKRVQLLKKFIKIAAHCREFKNLNSFFAIIMGMSNPAVSRLSQTWERIIANTIRQVRHCRSQPFNPDICQ---PNKNQAEVRGYVRK 853          

Query:  983 QQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVD-DFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIP-DPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKF-GRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            +Q   G+++V W M+Q   + SR  A+G+WQVL++E ILV +      +D  + +Y F D DF        G S      ++ ++L+ A+  L +  PDAL  MIL K+  +R  E+ E IY ELLH+KA +HLS+ V+++L++VL++E H   G V+F QG +G SWYII KGSV+V   GKG+V  L   +DFG+LAL+N++PRAA+IILRE++CHFL++DK+DF RIL+DVE NTVRL EHGK VL+ E+  T S  + S+  N         Y+VM+GTPEKI++HLLE          + LD  G  P DP +  F+LT+  F+ +  LC  L   +    +Q    G      ++E D  ++  K +VV  +  W  +      ED V   F E        ++  ++S L+        L EQ+++             + +K+Q     SN   + L  I PIK KD   + ++    ++  L L V+S VQ ++  V +    P     L +M S G+R   ++E   V   L +N ++++    E  E+    +   G     T+   I +     ++A  LT FDW+LF  +H  EL++ + GR+KF G IT+NL+ F+R F  +QYWVVTE+C C++L +R  ++KK IK+AS L E KN++S FAV+ GL+NSAV R    W                       + A+R  + K  PP IPF  ++LKD+TFI++ N +Y  D ++NFEKM +        +H R       +S      +    I L  Y++N K +DNQ+QLTQ S  LE
Sbjct:   68 RQCCSGKELVDWLMKQNECLQSRSQAVGMWQVLVDEGILVHVKHELNFQDKEAQFYRFQDSDF--------GLSHIPNEKESEEELQEALALLSQLGPDALLTMILRKTPSQRTPEDIEVIYEELLHVKAAAHLSTSVRKELAAVLVFESHAKAGTVLFSQGDKGTSWYIIWKGSVNVITHGKGIVTTLHEGEDFGQLALLNDAPRAATIILREDNCHFLRVDKQDFIRILKDVEANTVRLEEHGKTVLVLEQS-TQSARQGSAGTNSK-------YTVMSGTPEKILEHLLET---------IKLDSNGYDPIDPCVIDFLLTHKVFMPTSQLCPALQHQYPQMLDQFCFSG-----SEQEKDAYIIDTKQKVVKLISHWVAVYGFLLKEDPVAMDFLE--------KEVAADSRLS------GMLKEQYRE------------RRRTKNQHFDWFSNC-DEALGRIQPIKAKDKILYEIYRPDHKALTLMLPVDSPVQDVLSGVVE----PGGGHVLVKMNSTGDRAELKLEASAVYTALGLNERLFICTSSEV-EHLRPLKEQQGPEQGTTD---ILEQIGSKDMAAELTNFDWELFTAVHEVELVYYIFGRNKFPGAITANLERFVRHFNKLQYWVVTELCLCEDLMKRALLLKKFIKIASVLKEQKNLNSFFAVMFGLSNSAVQREYQIW-----------------------NVAYRLAVAKLNPPYIPFMPLLLKDMTFIHEGNPSYV-DKLVNFEKMGVLCQ-----IHSRVISSSHSDSDHSLPQRSPTNIRL--YIQNLKVIDNQRQLTQRSRALE 797          

Query:  983 QQVMVGEDMVSW-MRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVD-DFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIP-DPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTEN 2176
            +Q   G+++V W M+Q   + SR  A+G+WQVL++E ILV +      +D  + +Y F D DF        G S      ++ ++L+ A+  L +  PDAL  MIL K+  +R  E+ E IY ELLH+KA +HLS+ V+++L++VL++E H   G V+F QG +G SWYII KGSV+V   GKG+V  L   +DFG+LAL+N++PRAA+IILRE++CHFL++DK+DF RIL+DVE NTVRL EHGK VL+ E+  T S  + S+  N         Y+VM+GTPEKI++HLLE          + LD  G  P DP +  F+LT+  F+ +  LC   L           ++G      ++E D  ++  K +VV  +  W  +      ED V   F E 
Sbjct:   84 RQCCSGKELVDWLMKQNECLQSRSQAVGMWQVLVDEGILVHVKHELNFQDKEAQFYRFQDSDF--------GLSHIPNEKESEEELQEALALLSQLGPDALLTMILRKTPSQRTPEDIEVIYEELLHVKAAAHLSTSVRKELAAVLVFESHAKAGTVLFSQGDKGTSWYIIWKGSVNVITHGKGIVTTLHEGEDFGQLALLNDAPRAATIILREDNCHFLRVDKQDFIRILKDVEANTVRLEEHGKTVLVLEQS-TQSARQGSAGTNSK-------YTVMSGTPEKILEHLLET---------IKLDSNGYDPIDPCVIDFLLTHKVFMPTSQLCPAEL-----------SEG-----SEQEKDAYIIDTKQKVVKLISHWVAVYGFLLKEDPVAMDFLEK 443          

Query: 2546 DGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKF-GRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLE 3448
            D  R   ++E   V   L +N ++++    E  E+    +   G     T+   I +     ++A  LT FDW+LF  +H  EL++ + GR+KF G IT+NL+ F+R F  +QYWVVTE+C C++L +R  ++KK IK+AS                   NSAV RL  TWER+ SK ++++     L+DP+RNH A+R  + K  PP IPF  ++LKD+TFI++ N +Y  D ++NFEKM      + Q+ H R       +S      +    I L  Y++N K +DNQ+QLTQ S  LE
Sbjct:  490 DKNRAELKLEASAVYTALGLNERLFICTSSEV-EHLRPLKEQQGPEQGTTD---ILEQIGSKDMAAELTNFDWELFTAVHEVELVYYIFGRNKFPGAITANLERFVRHFNKLQYWVVTELCLCEDLMKRALLLKKFIKIAS------------------VNSAVQRLYKTWERIPSKIKRIYCTYERLMDPSRNHRAYRLAVAKLNPPYIPFMPLLLKDMTFIHEGNPSYV-DKLVNFEKMVWLKGVLCQI-HSRVISSSHSDSDHSLPQRSPTNIRL--YIQNLKVIDNQRQLTQRSRALE 765          

Query:  995 VGEDMVSWM-RQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCD-----------DLETAINYLMKPAPDALFRMILH-KSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDK-----EDFNRILRD-----------VELNTVRLTEHGKDVLLFEKRIT-------DSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLEN-RIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQK----TEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTI------DLQNYVRNFKCLDNQKQLTQLSLGLEAK 3454
            VG ++V W+  Q + +  R  A+ +WQVLLE  +L+S+       DS S YY F                   SF+ CD           +   A+  L++ AP   FR      S  E + E    I  E+L +KAL  L+S V+ +L++ L  +      K +  Q SE          +        G VC LR + D         S    S+  RE     L ++      +D  RIL++             L  V L E G+DVL+ + R+T       D P   SS            Y V++GTP KI++HLL + R+D  +      +R   +   +L+ F+LTY  F+++H LC  LL ++     +   +G+             L RK +V+  +  W R+      E+  ++SF + L   +  +          EF +L   L++FQK              Q+SK    Q+  K +       +  P  + K++    V+ S      +         +++  V    +   +++ L  +   GER + +  D     +L+ NGK+ +    +  E      +   L      L  I    +  ++A  LT+ DW LFK+IH  EL++  L R      T+ L   +++   +Q WV++EV  C +L +RV ++KK IK+A+     +N++S FA++MGLN +AV+RL  TWE+   K +KLF +L  + DP+ NH A+R+  K+  PP IPF  ++LKD+TFI++ NKT F DN++NFEK+ M A ++  + HC++             D+  N +      D++  V     +DNQ+ L +LS  LE +
Sbjct:  105 VGVELVQWLCEQCVCVRYRTAAVRVWQVLLELGVLLSVDQRVVFSDSNS-YYQF-------------------SFEECDSPSCEFRLNEAEWPEAVKLLLQLAPYVQFRSGGGTNSPSEEDSEGNRDICSEILQLKALERLTSTVQSELAAALARKTR----KALSEQDSETTEARQQESCTPSEESSPLGGVCSLRDSGDSSSGGSGGGSGGTGSVCCREELTSRLGLEAVQRLAKDGCRILQNHNYQISDRSQAEALGRVCLKERGRDVLVLQ-RVTSSLTSPSDRPSPTSSGGGLRQDDSNKRYVVVSGTPLKILEHLLSDLRLDDQRGAQE--NRESEM---LLDDFLLTYLVFMSTHDLCQALLGHYGGARCRGQEEGKD-----------ALFRKRKVLQLVSHWSRLYKDFLKEEEHVRSFMKTLYRCVLEDLY--------EFPSLEKDLKEFQKLLRRRHTVDDCPPNQKSKQMHQQLSLKENYLH----LRTPQTEHKEV-MCCVYVSADSYLSVHTHPSLEAHELLRIVGMKMDRAEEDMVLAVVSHTGERRVLQPSDCVYSESLTPNGKL-VACRRDLNEVLPPLADSAELNKRPVRLLGI----NTWDVATALTHLDWTLFKSIHEQELVYYTLSRPPGSGHTAALSLLLQRCNEVQQWVMSEVLMCVSLNKRVQLLKKFIKIAAHCKAQRNLNSAFAIIMGLNTAAVSRLNQTWEKCPGKFKKLFSELELITDPSLNHKAYREAFKRMKPPKIPFMPLLLKDITFIHEGNKT-FHDNLVNFEKLHMIADTVRNIRHCQS-------------DQAGNEVIGVDSADVRASVHCLHIIDNQQTLFKLSHKLEPR 898          

Query:  218 MSIDVSQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHXXXXXXXASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEMKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQLSSNSLPVEFSTE 3496
            MSIDVSQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHGCCGGGGASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCE+KSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGL+NIKTE SSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQLSSNSLPVEFSTE
Sbjct:    1 MSIDVSQKAKLILCLDKPSHLRTSEDLDAIYNCLKLIKSYSGLHPYLLQQMCLEVQYEHLKERIVVYQGGKPEKNCYVVMSGSLIIVDRDKLPEILNQDLNLRDTIFQPLITEGCAFGNNFRLNSTNNHIKPYSINLLDSKAVVTQEDCELLYMDQKIFQEIWSKNEKFLRDLNLSRDISVMDNNVRAMSIESAGASGLPDDANSQNLSVPVRTTNPGHNPAIINAAFFIYKSSKHLLVSLPSSFGGKIVSKSSTQQVMVGEDMVSWMRQLIKINSRLLAIGIWQVLLEECILVSLTSPYCLRDSASDYYVFVDDFYHGCCGGGGASGNSKSFQTCDDLETAINYLMKPAPDALFRMILHKSGKERNKEEFEFIYGELLHIKALSHLSSMVKRQLSSVLMYEIHPVVGKVVFYQGSEGNSWYIILKGSVDVHIKGKGVVCRLRTNDDFGKLALVNNSPRAASIILRENDCHFLKIDKEDFNRILRDVELNTVRLTEHGKDVLLFEKRITDSPGRKSSLMNQNNPTGFYMYSVMAGTPEKIIDHLLENRIDTNKSYAVILDRVGTIPDPMLETFILTYFAFLTSHGLCSLLLVYFQNYNNQTPNDGRATPIEDKEHDQIVLLRKTRVVHFLYWWCRISDGAFFEDHVIQSFTENLLNILTAEKKNSNSLLNKEFLALNCLLEQFQKTEIAASKKIGQRSKFSKHQIGSKTSNATSQQLVDIPPIKGKDLSTFTVHFSGGRSCMLRLTVESTVQQIIETVAKHENIPVDNLCLCEVKSDGERILFEMEDVGVMYNLSVNGKIYLMAFEEYKENFLDERNHVGLSNIKTESSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELLFKVLGRSKFGRITSNLDAFIRQFTNIQYWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYLKKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLHCRARPMIFENSTSMKKDKLSNTIDLQNYVRNFKCLDNQKQLTQLSLGLEAKQLSSNSLPVEFSTE 1093          

Query: 2597 LSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLG---------RSKFGRITSNLDAFIRQFTNIQ----------YWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYL--KKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLH 3301
            LS+N + YL       +   DE+  V L   K  L+ +       E+A  LT  D+ LF++I   E +   FK+                   SNL+ F   + N +          +W  TE+C   N+ +R  ++KK IK+A    +LKN +S   ++ GL  + V+RL++TWE++ +K+ KL++DL  L D + N    RQ +  + + PP+IP  A+  KDL  I+  NKT   D +INFEK++M A+ + ++L 
Sbjct:  170 LSLNQRYYLKNNITDSQLITDEQAKVLLNESKVTLAQM----EPIEIATRLTLIDYALFRDIPSAEYINYVFKLPPLKDDDKKALDPSLEDYKSNLEGFSNGYENYKNFEDLINRESFWPTTEICMEPNINKRAELIKKFIKVAKFCKDLKNFNSLMCIITGLTLTPVSRLKLTWEKVPNKYIKLYEDLSDLTDMSLNFRRIRQLVLPEISEPPLIPCLALHSKDLAAIHLGNKTSTKDELINFEKLRMMASEIRKLLR 424          

Query: 2597 LSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLG---------RSKFGRITSNLDAFIRQFTNIQ----------YWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYL--KKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLH 3301
            LS+N + YL       +   DE+  V L   K  L+ +       E+A  LT  D+ LF++I   E +   FK+                   SNL+ F   + N +          +W  TE+C   N+ +R  ++KK IK+A    +LKN +S   ++ GL  + V+RL++TWE++ +K+ KL++DL  L D + N    RQ +  + + PP+IP  A+  KDL  I+  NKT   D +INFEK++M A+ + ++L 
Sbjct:  229 LSLNQRYYLKNNITDSQLITDEQAKVLLNESKVTLAQM----EPIEIATRLTLIDYALFRDIPSAEYINYVFKLPPLKDDDKKALDPSLEDYKSNLEGFSNGYENYKNFEDLINRESFWPTTEICMEPNINKRAELIKKFIKVAKFCKDLKNFNSLMCIITGLTLTPVSRLKLTWEKVPNKYIKLYEDLSDLTDMSLNFRRIRQLVLPEISEPPLIPCLALHSKDLAAIHLGNKTSTKDELINFEKLRMMASEIRKLLR 483          

Query: 2597 LSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLG---------RSKFGRITSNLDAFIRQFTNIQ----------YWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYL--KKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLH 3301
            LS+N + YL       +   DE+  V L   K  L+ +       E+A  LT  D+ LF++I   E +   FK+                   SNL+ F   + N +          +W  TE+C   N+ +R  ++KK IK+A    +LKN +S   ++ GL  + V+RL++TWE++ +K+ KL++DL  L D + N    RQ +  + + PP+IP  A+  KDL  I+  NKT   D +INFEK++M A+ + ++L 
Sbjct:  229 LSLNQRYYLKNNITDSQLITDEQAKVLLNESKVTLAQM----EPIEIATRLTLIDYALFRDIPSAEYINYVFKLPPLKDDDKKALDPSLEDYKSNLEGFSNGYENYKNFEDLINRESFWPTTEICMEPNINKRAELIKKFIKVAKFCKDLKNFNSLMCIITGLTLTPVSRLKLTWEKVPNKYIKLYEDLSDLTDMSLNFRRIRQLVLPEISEPPLIPCLALHSKDLAAIHLGNKTSTKDELINFEKLRMMASEIRKLLR 483          

Query: 2597 LSVNGKIYLMAFEEYKENFLDERNHVGLTNIKTELSSIFDSTSIDELAFHLTYFDWQLFKNIHVYELL---FKVLG---------RSKFGRITSNLDAFIRQFTNIQ----------YWVVTEVCQCQNLQRRVNIVKKMIKLASRLSELKNISSGFAVLMGLNNSAVARLQMTWERLSSKHRKLFQDLCSLLDPTRNHCAFRQYL--KKTPPPIIPFFAIMLKDLTFINDANKTYFDDNMINFEKMQMYAASMHQVLH 3301
            LS+N + YL       +   DE+  V L   K  L+ +       E+A  LT  D+ LF++I   E +   FK+                   SNL+ F   + N +          +W  TE+C   N+ +R  ++KK IK+A    +LKN +S   ++ GL  + V+RL++TWE++ +K+ KL++DL  L D + N    RQ +  + + PP+IP  A+  KDL  I+  NKT   D +INFEK++M A+ + ++L 
Sbjct:  229 LSLNQRYYLKNNITDSQLITDEQAKVLLNESKVTLAQM----EPIEIATRLTLIDYALFRDIPSAEYINYVFKLPPLKDDDKKALDPSLEDYKSNLEGFSNGYENYKNFEDLINRESFWPTTEICMEPNINKRAELIKKFIKVAKFCKDLKNFNSLMCIITGLTLTPVSRLKLTWEKVPNKYIKLYEDLSDLTDMSLNFRRIRQLVLPEISEPPLIPCLALHSKDLAAIHLGNKTSTKDELINFEKLRMMASEIRKLLR 483