PPIP5K2_N domain-containing protein

Overview


Name	PPIP5K2_N domain-containing protein
Smed ID	SMED30016945
Length (bp)	1626

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of PPIP5K2_N domain-containing protein (SMED30016945) t-SNE clustered cells

Violin plots show distribution of expression levels for PPIP5K2_N domain-containing protein (SMED30016945) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PPIP5K2_N domain-containing protein (SMED30016945) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PPIP5K2_N domain-containing protein (SMED30016945) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016945

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
prepharyngeal region	SMED30016945	h1SMcG0010019	dd_Smed_v6_17573_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30016945	h1SMcG0010019	dd_Smed_v4_4245_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of PPIP5K2_N domain-containing protein vs. TrEMBL
Match: A0A267FU33 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033074g3 PE=4 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 3.038e-32
Identity = 106/400 (26.50%), Postives = 183/400 (45.75%), Query Frame = 1

Query:  370 KLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPE-SMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWF 1566
            K + C   +     GW +++S  L  +  LSSWF+ + +   + +D  V    C I LS  D FQ +NFP +L   + + +R+ WT G + +  +KD      +++NG PWS   + +V+AR ++L +IR M+   + L  ST++K D +D++FFRS S      C E   P+  F+L+L     L ++   +   + + N    + T G       H      L    W     +   TR L+T L Q+L   GW   ++I+  R + D S  +F R  P    ++CL     + +  +NA  +V   +       Y I     +R F G  + +  +G  +   N +  +  +  +  I+  ++  GW L+ SAD S      D   +    +++LWF
Sbjct:   85 KQVACTLLQDLAHKGWQVLNSSELCRNKDLSSWFFERTNEACVNYDSTV----CCIALSGFDKFQLVNFPKQLLAKVADAVRRTWTLGIQEE--MKDAYGSMEMKMNGNPWSASERGAVEARRMILEIIRAMASEGYVLCMSTSIK-DTTDSLFFRSASAADQPSCSELGSPDASFVLSLNRHDRLRLIEAPSEAQEVVRNVLLHHWTSGLTGDRDYHGSREFKLGGSPWWTEGAESVRTRLLITLLLQELRDKGWRLVQTIELCRRLNDKSVFVFARAQPESSLHWCLSLHSKSVLRFVNAPVEVVDALRLVIAGNY-IHGIKTERVFAGY-HQVRLRGRPWSSHNGNDHVHGRHMMLGILEAMQQRGWSLVCSADVSAIYHHADSGQDYPVDVHSLWF 475

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BLAST of PPIP5K2_N domain-containing protein vs. TrEMBL
Match: A0A267EYC4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033074g1 PE=4 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 6.670e-32
Identity = 105/400 (26.25%), Postives = 183/400 (45.75%), Query Frame = 1

Query:  370 KLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPE-SMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWF 1566
            K + C   +     GW +++S  L  +  LSSWF+ + +   + +D  V    C I LS  D FQ +NFP +L   + + +R+ WT G + +  +KD      +++NG PWS   + +V+AR ++L +IR M+   + L  ST++K D +D++FFRS +      C E   P+  F+L+L     L ++   +   + + N    + T G       H      L    W     +   TR L+T L Q+L   GW   ++I+  R + D S  +F R  P    ++CL     + +  +NA  +V   +       Y I     +R F G  + +  +G  +   N +  +  +  +  I+  ++  GW L+ SAD S      D   +    +++LWF
Sbjct:   85 KQVACTLLQDLAHKGWQVLNSSELCRNKDLSSWFFERTNEACVNYDSTV----CCIALSGFDKFQLVNFPKQLLAKVADAVRRTWTLGIQEE--MKDAYGSMEMKMNGNPWSASERGAVEARRMILEIIRAMASEGYVLCMSTSIK-DTTDSLFFRSATAADQPSCSELGSPDASFVLSLNRHDRLRLIEAPSEAQEVVRNVLLHHWTSGLTGDRDYHGSREFKLGGSPWWTEGAESVRTRLLITLLLQELRDKGWRLVQTIELCRRLNDKSVFVFARAQPESSLHWCLSLHSKSVLRFVNAPVEVVDALRLVIAGNY-IHGIKTERVFAGY-HQVRLRGRPWSSHNGNDHVHGRHMMLGILEAMQQRGWSLVCSADVSAIYHHADSGQDYPVDVHSLWF 475

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BLAST of PPIP5K2_N domain-containing protein vs. TrEMBL
Match: A0A267EJP5 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032498g1 PE=4 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 8.374e-31
Identity = 115/424 (27.12%), Postives = 186/424 (43.87%), Query Frame = 1

Query:  343 SFQSDSAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVE-NEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGC---------DAN-LGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGD---AFRGSN-LHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFC 1569
            S +S++   KL      +     GW  V S  L  S  L +WF+ + +      D+    +  C + LS++D  Q I FP  L   +++ IRQ W+ G +             L+L+G PW    +++VDAR ++L ++R M     RL  S+++K D +D++FF      L     + +    F+L+L     L ++G          D N L   I      Y  KG +     +    L L    W         +R L+T L Q L  IGW   E++D  R ++D S +LF R PP    + C+     + +  INA EDV + +     + Y   R       Y   + I  +G    AF G++ +HG     L LA + ++ +D+GW L+ SAD S +    D   +    +++ WFC
Sbjct:   88 SSRSEAIAGKLAGIAILRRLLSRGWRAVVSSDLCRSNDLGTWFFSRTEPGVDFADESDRTSSICCLALSSSDRLQLIGFPASLTPRVVDRIRQEWSCGVQRGPEAVCNGQAVELKLHGNPWLASEQEAVDARQMLLAIVREMHRWGCRLYLSSSLK-DTTDSLFFLC-PRRLKPPVEQLLATEMFVLSLNRRDRLRLMGTSEQSEVEDKDCNQLMDVIRECVLNYWPKGLRQERDWYGARELHLTGSPWWTEGSDSVHSRLLITLLLQRLRQIGWRVVETVDVCRRLSDKSILLFERSPPRSTLHCCISLNGTSLLRFINAPEDVVSTMQQVVSDNY--ARGIKSEKIYAGYHQIHLRGQPWSAFSGNDHMHG---RHLMLAVLSAMRQDLGWSLVCSADVSAKYHHSDSGQDYPLDVHSWWFC 504

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BLAST of PPIP5K2_N domain-containing protein vs. TrEMBL
Match: A0A267GD37 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011687g1 PE=4 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 1.735e-30
Identity = 115/426 (27.00%), Postives = 187/426 (43.90%), Query Frame = 1

Query:  343 SFQSDSAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVE-NEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGC---------DAN-LGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGD---AFRGSN-LHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRP 1575
            S +S++   KL      +     GW  V S  L  S  L +WF+ + +      D+    +  C + LS++D  Q I FP  L   +++ IRQ W+ G +             L+L+G PW    +++VDAR ++L ++R M     RL  S+++K D +D++FF      L     + +    F+L+L     L ++G          D N L   I      Y  KG +     +    L L    W         +R L+T L Q L  IGW   E++D  R ++D S +LF R PP    + C+     + +  INA EDV + + +   + Y   R       Y   + I  +G    AF G++ +HG     L LA + ++ +D+GW L+ SAD S +    D   +    +++ WF  P
Sbjct:   88 SSRSEAIAGKLAGIAILRRLLSRGWRAVVSSDLCRSNDLGTWFFSRTEPGVDFADESDRTSSICCLALSSSDRLQLIGFPASLTPRVVDRIRQEWSCGVQRGPEAVCNGQAVELKLHGNPWLASEQEAVDARQMLLAIVREMHRWGCRLYLSSSLK-DTTDSLFFLC-PRRLKPPVEQLLATEMFVLSLNRRDRLRLMGTSEQSEVEDKDCNQLMDVIRECVLNYWPKGLRQERDWYGARELHLTGSPWWTEGSDSVHSRLLITLLLQRLRQIGWRVVETVDVCRRLSDKSILLFERSPPRSTLHCCISLNGTSLLRFINAPEDVVSAMRHVVSDNY--ARGIKSEKIYAGYHQIHLRGQPWSAFSGNDHMHG---RHLMLAVLSAMRQDLGWSLVCSADVSAKYHHSDSGQDYPLDVHSWWFSAP 506

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BLAST of PPIP5K2_N domain-containing protein vs. TrEMBL
Match: A0A267GR50 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002187g2 PE=4 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.296e-28
Identity = 114/425 (26.82%), Postives = 183/425 (43.06%), Query Frame = 1

Query:  343 SFQSDSAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVE-NEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGC---------DAN-LGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGD---AFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRP 1575
            S +S++   KL      +     GW  V S  L  S  L +WF+ + +      D+    +  C + LS++D  Q I FP  L   ++  IRQ W+ G +             L+L+G PW    +++V+AR ++L ++R M     RL  S+++K D +D++FF      L     +      F+L+L     L ++G          D N L   I      Y  KG +     +    L L    W         +R L+T L Q L  IGW   E++D  R ++D S +LF R PP    + C+     + +  INA EDV + +     + Y   R       Y   + I  +G    AF G N H ++   L LA + ++ +D+GW L+ SAD S +    D   +    +++ WF  P
Sbjct:   88 SSRSEAIAGKLAGIAILRRLLSRGWRAVVSSDLCRSNDLGTWFFSRTEPGVDFADESDRTSSICCLALSSSDRLQLIGFPASLTPRVVERIRQEWSCGVQRGPEAVCNGQAVELKLHGNPWLASEQEAVEARQMLLAIVREMHRWGCRLYLSSSLK-DTTDSLFFLC-PRRLKPPVEQLQATEMFVLSLNRRDRLRLMGTSEQSEVEDKDCNQLMDVIRECVLNYWPKGLRQERDWYGARELHLTGSPWWTEGSDSVHSRLLITLLLQRLRQIGWRVVETVDVCRRLSDKSILLFERSPPRSTLHCCISLNGTSLLRFINAPEDVVSAMQQVVSDNY--ARGIKSEKIYAGYHQIHLRGQPWSAFSG-NDH-MLGRHLMLAVLSAMRQDLGWSLVCSADVSAKYHHSDSGQDYPLDVHSWWFAAP 506

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BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Nematostella
Match: EDO36791 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHJ7])

HSP 1 Score: 90.8929 bits (224), Expect = 2.188e-19
Identity = 115/485 (23.71%), Postives = 193/485 (39.79%), Query Frame = 1

Query:  148 EIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSDSAKFK------LMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGK-QSVDARYLVLCLIR-FMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYET---KGSKLLYTKHNYVS---LDLNSKVWSRRNEKETETRRLMTC-LFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFK----------GDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDE 1527
            E++  P+ +CV  +  +  + IN   +    + E   E+W + I+     +T  K      L  F F  +   F        +  K  +   K+GW L     L+     S WF+ +         +  E ++  + LS+ D   F+N P +    I   I + W KG K  K  ++T+ L   QL G PW  +GK  S+ AR L+  L   F   +N  L     ++  A D+  FR +         ES  E  FM  +   G   +L  DA             ET   +G   +  +  YV+     L    W  R  K++   RL+ C L ++L +  W        ++H  +   ++F +  P+ +   CLCP   N + L+NA  ++   +      ++P  R   +R +   A  ++FK           D+F  SN+         +  I+  L+  GW L +SAD + + M   E
Sbjct:   33 ELQSPPNYLCVTAVKPATIHLINGGKDEQIIIQEAITESWEQGIKD----ETPQKHGHSWTLQEFPFGYNKQGFYCPAREIRVLSKIIQSLDKNGWLLAGVADLSRRFVFSQWFFIRGSG------QHSELDYPCVSLSSVDTILFVNIPSQFYARIKELILKYWDKGIKESKEEENTLEL---QLKGKPW--HGKILSMPARLLMTQLFGLFHRKYNLELYCRLNLRCKA-DSFLFRPK-------VKESKDENTFM-GICLYGKSGVLIIDAQSEAITIVRKVLQETWMWRGG--IKDEKEYVACYGFTLAGSPWWSRKRKQSAMSRLVICRLIEELQSSSWKIITGAAFSKHSMNKDMLVFQKCKPMNVSSMCLCPVGANKLRLVNATSEIFATVRELIQTHWPT-RIKRERRYRTPAAFLEFKLNGKPWSGKTTDSFSASNM---------MCYIMQELQRQGWKLALSADIAAKYMYPGE 481

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BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Nematostella
Match: EDO25994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TD61])

HSP 1 Score: 56.6102 bits (135), Expect = 2.891e-9
Identity = 37/139 (26.62%), Postives = 71/139 (51.08%), Query Frame = 1

Query:  331 LHFFSFQSDSAKFKLMFCK--FHKLFYKH---GWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDA 732
            L  F F   S++ + +  +    KL +K    GW LV +  L+  + L ++F+ K +       + V   F  I LS++D  QF+NF   L    ++ I   WT+G   + +  +  NL+ ++++G PW  +G++S+++
Sbjct:   72 LTGFPFDKGSSQVEAVNARKLVSKLLWKLNNVGWKLVMTTDLSRKLGLGTFFFVKEET------EAVTYTFPCINLSSSDKIQFVNFSQRLYPQFLSVIESTWTQGI--QMIESEEENLYEVKMHGDPWKGFGQESIES 202

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BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Nematostella
Match: EDO45093 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTU8])

HSP 1 Score: 55.0694 bits (131), Expect = 1.802e-8
Identity = 45/228 (19.74%), Postives = 90/228 (39.47%), Query Frame = 1

Query:  532 AIGLSNTDGFQFINFPIELENPIINCIRQNWT-KGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNS--TAMKQDASDTMFFRSQSNMLN---------------VDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCT 1161
            +I L+ TDG + IN+P  +++ +   +  NW  +G    +  ++    +  +LNG PW    K+S+ ARYL+L L+  +  + W ++     + +     T+ F+  + M                 ++ P++  E   M  +++      +  +      +  SC                 V   +N   W   ++ +   R +M  L Q L+   W P  S D +
Sbjct:    3 SISLNGTDGVRLINYPANMQSVVQQVLVDNWAWRGGVASE--REFYGGYEYKLNGNPWWSEEKESIMARYLILKLLEALQGYGWHVIGGFDVSRRLTTKSTLIFQQSAPMKTPLLCISASGSDKLRFINTPDA--ELSIMREIMHKHWPKKISAEKRKDTALGVSC-----------------VQFKMNGTPWHGEDDDKYYARSMMCFLLQALSKRSWKPVLSADVS 209

HSP 2 Score: 47.7506 bits (112), Expect = 4.482e-6
Identity = 44/237 (18.57%), Postives = 96/237 (40.51%), Query Frame = 1

Query:  892 FMLALINPGSLSILGCDANLGQFIANS-CDKYETKGS----KLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYS-IDFKGDAFRGSNLHG----VILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCR 1572
            F ++L     + ++   AN+   +     D +  +G     +  Y  + Y    LN   W    ++    R L+  L + L   GW      D +R +T  S+++F +  P++    C+     + +  IN  +   +++     +++P + +  KR    +  S + FK     G+  HG        +  +  ++  L    W  ++SAD S +    D++ +    +++ WF +
Sbjct:    2 FSISLNGTDGVRLINYPANMQSVVQQVLVDNWAWRGGVASEREFYGGYEY---KLNGNPWWSEEKESIMARYLILKLLEALQGYGWHVIGGFDVSRRLTTKSTLIFQQSAPMKTPLLCISASGSDKLRFINTPDAELSIMREIMHKHWPKKISAEKRKDTALGVSCVQFK---MNGTPWHGEDDDKYYARSMMCFLLQALSKRSWKPVLSADVSAQYDKDDDDEKYPKDVHSWWFMK 232

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BLAST of PPIP5K2_N domain-containing protein vs. Planmine SMEST
Match: SMESG000064344.1 (SMESG000064344.1)

HSP 1 Score: 1019.61 bits (2635), Expect = 0.000e+0
Identity = 489/489 (100.00%), Postives = 489/489 (100.00%), Query Frame = 1

Query:  118 MGVNYSKYIPEIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSDSAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRPLPT 1584
            MGVNYSKYIPEIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSDSAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRPLPT
Sbjct:    1 MGVNYSKYIPEIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSDSAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRPLPT 489

[Close]

BLAST of PPIP5K2_N domain-containing protein vs. Planmine SMEST
Match: SMESG000064337.1 (SMESG000064337.1)

HSP 1 Score: 589.726 bits (1519), Expect = 0.000e+0
Identity = 279/490 (56.94%), Postives = 366/490 (74.69%), Query Frame = 1

Query:  118 MGVNYSKYIPEIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSD-SAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRPLPT 1584
            MG +YS+Y+ EI+++PSN+CV++  +   YG+NL  ++I  + +++ E WGKE++IK  C++I+KF     + + +  +  SAK K MFC+F K+F   GWSLVSSPTLTF  SLS+WF++K  NP ++     ENEFC IGLS+ D  QFI+FP  LE  +INC ++NW KGT+ K++I    + WSLQLN    S  G+QS+DAR LVLCLIRFMSHHNWRLVNSTAMK DASDTMFFR  +   ++DCPE+MPEYYFMLAL+     SILG D  +   +A+SC KYE+KG +    KH Y S+   S +WSRRNEK  ET+ L+TC+FQ+LAAIGW+P ESIDCTR I DLSSI F R+P VRM YFCLCPRKYNGICLINA E+VQ+++++TFV+YY I++ +IKRS YG+A SIDF G  FRG N HG++LFQ+ALAAII+ LK+ GW+L+VSADTSNET++  + ++IKWSIY LWF + L +
Sbjct:    1 MGNDYSQYMLEIRQIPSNICVIHATSFLLYGVNLTQDLIKSMADIYLEIWGKEVKIKPMCNSIVKFKPHKLIMYTAGDAKTSAKSKQMFCRFQKIFCHFGWSLVSSPTLTFQFSLSTWFFYKNINPCMVETGGSENEFCVIGLSSFDKLQFIDFPQALEQSVINCTKKNWIKGTQEKEVIYTGSSSWSLQLNVTDTS--GEQSLDARNLVLCLIRFMSHHNWRLVNSTAMKPDASDTMFFRQYTKAFSIDCPETMPEYYFMLALMGKDYFSILGGDTVIWNTVADSCRKYESKGIETPKVKHKYPSVTAVSDLWSRRNEKSMETKLLITCIFQELAAIGWLPIESIDCTRSIKDLSSIAFVRIPAVRMIYFCLCPRKYNGICLINAVEEVQSIVYDTFVQYYVIKKEEIKRSTYGIATSIDFIGSPFRGGNEHGILLFQVALAAIITTLKEAGWFLVVSADTSNETLSRSKQSDIKWSIYGLWFSKLLAS 488

[Close]

BLAST of PPIP5K2_N domain-containing protein vs. Planmine SMEST
Match: SMESG000064337.1 (SMESG000064337.1)

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 274/480 (57.08%), Postives = 358/480 (74.58%), Query Frame = 1

Query:  148 EIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSD-SAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKDIGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRPLPT 1584
            EI+++PSN+CV++  +   YG+NL  ++I  + +++ E WGKE++IK  C++I+KF     + + +  +  SAK K MFC+F K+F   GWSLVSSPTLTF  SLS+WF++K  NP ++     ENEFC IGLS+ D  QFI+FP  LE  +INC ++NW KGT+ K++I    + WSLQLN    S  G+QS+DAR LVLCLIRFMSHHNWRLVNSTAMK DASDTMFFR  +   ++DCPE+MPEYYFMLAL+     SILG D  +   +A+SC KYE+KG +    KH Y S+   S +WSRRNEK  ET+ L+TC+FQ+LAAIGW+P ESIDCTR I DLSSI F R+P VRM YFCLCPRKYNGICLINA E+VQ+++++TFV+YY I++ +IKRS YG+A SIDF G  FRG N HG++LFQ+ALAAII+ LK+ GW+L+VSADTSNET++  + ++IKWSIY LWF + L +
Sbjct:    3 EIRQIPSNICVIHATSFLLYGVNLTQDLIKSMADIYLEIWGKEVKIKPMCNSIVKFKPHKLIMYTAGDAKTSAKSKQMFCRFQKIFCHFGWSLVSSPTLTFQFSLSTWFFYKNINPCMVETGGSENEFCVIGLSSFDKLQFIDFPQALEQSVINCTKKNWIKGTQEKEVIYTGSSSWSLQLNVTDTS--GEQSLDARNLVLCLIRFMSHHNWRLVNSTAMKPDASDTMFFRQYTKAFSIDCPETMPEYYFMLALMGKDYFSILGGDTVIWNTVADSCRKYESKGIETPKVKHKYPSVTAVSDLWSRRNEKSMETKLLITCIFQELAAIGWLPIESIDCTRSIKDLSSIAFVRIPAVRMIYFCLCPRKYNGICLINAVEEVQSIVYDTFVQYYVIKKEEIKRSTYGIATSIDFIGSPFRGGNEHGILLFQVALAAIITTLKEAGWFLVVSADTSNETLSRSKQSDIKWSIYGLWFSKLLAS 480

[Close]

BLAST of PPIP5K2_N domain-containing protein vs. Planmine SMEST
Match: SMESG000064337.1 (SMESG000064337.1)

HSP 1 Score: 485.723 bits (1249), Expect = 3.180e-169
Identity = 231/414 (55.80%), Postives = 304/414 (73.43%), Query Frame = 1

Query:  118 MGVNYSKYIPEIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSD-SAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFY 1356
            MG +YS+Y+ EI+++PSN+CV++  +   YG+NL  ++I  + +++ E WGKE++IK  C++I+KF     + + +  +  SAK K MFC+F K+F   GWSLVSSPTLTF  SLS+WF++K  NP ++     ENEFC IGLS+ D  QFI+FP  LE  +INC ++NW KGT+ K++I    + WSLQLN    S  G+QS+DAR LVLCLIRFMSHHNWRLVNSTAMK DASDTMFFR  +   ++DCPE+MPEYYFMLAL+     SILG D  +   +A+SC KYE+KG +    KH Y S+   S +WSRRNEK  ET+ L+TC+FQ+LAAIGW+P ESIDCTR I DLSSI F R+P VRM YFCLCPRKYNGICLINA E+VQ+++++TFV+YY I++ +IK + Y
Sbjct:    1 MGNDYSQYMLEIRQIPSNICVIHATSFLLYGVNLTQDLIKSMADIYLEIWGKEVKIKPMCNSIVKFKPHKLIMYTAGDAKTSAKSKQMFCRFQKIFCHFGWSLVSSPTLTFQFSLSTWFFYKNINPCMVETGGSENEFCVIGLSSFDKLQFIDFPQALEQSVINCTKKNWIKGTQEKEVIYTGSSSWSLQLNVTDTS--GEQSLDARNLVLCLIRFMSHHNWRLVNSTAMKPDASDTMFFRQYTKAFSIDCPETMPEYYFMLALMGKDYFSILGGDTVIWNTVADSCRKYESKGIETPKVKHKYPSVTAVSDLWSRRNEKSMETKLLITCIFQELAAIGWLPIESIDCTRSIKDLSSIAFVRIPAVRMIYFCLCPRKYNGICLINAVEEVQSIVYDTFVQYYVIKKEEIKVNLY 412

[Close]

BLAST of PPIP5K2_N domain-containing protein vs. Planmine SMEST
Match: SMESG000064337.1 (SMESG000064337.1)

HSP 1 Score: 474.937 bits (1221), Expect = 3.826e-165
Identity = 226/404 (55.94%), Postives = 296/404 (73.27%), Query Frame = 1

Query:  148 EIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETWGKEIQIKTYCDTIMKFDLKSCLHFFSFQSD-SAKFKLMFCKFHKLFYKHGWSLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQFINFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGKQSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDCPESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTKHNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRHITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEYYPIQRNDIKRSFY 1356
            EI+++PSN+CV++  +   YG+NL  ++I  + +++ E WGKE++IK  C++I+KF     + + +  +  SAK K MFC+F K+F   GWSLVSSPTLTF  SLS+WF++K  NP ++     ENEFC IGLS+ D  QFI+FP  LE  +INC ++NW KGT+ K++I    + WSLQLN    S  G+QS+DAR LVLCLIRFMSHHNWRLVNSTAMK DASDTMFFR  +   ++DCPE+MPEYYFMLAL+     SILG D  +   +A+SC KYE+KG +    KH Y S+   S +WSRRNEK  ET+ L+TC+FQ+LAAIGW+P ESIDCTR I DLSSI F R+P VRM YFCLCPRKYNGICLINA E+VQ+++++TFV+YY I++ +IK + Y
Sbjct:    3 EIRQIPSNICVIHATSFLLYGVNLTQDLIKSMADIYLEIWGKEVKIKPMCNSIVKFKPHKLIMYTAGDAKTSAKSKQMFCRFQKIFCHFGWSLVSSPTLTFQFSLSTWFFYKNINPCMVETGGSENEFCVIGLSSFDKLQFIDFPQALEQSVINCTKKNWIKGTQEKEVIYTGSSSWSLQLNVTDTS--GEQSLDARNLVLCLIRFMSHHNWRLVNSTAMKPDASDTMFFRQYTKAFSIDCPETMPEYYFMLALMGKDYFSILGGDTVIWNTVADSCRKYESKGIETPKVKHKYPSVTAVSDLWSRRNEKSMETKLLITCIFQELAAIGWLPIESIDCTRSIKDLSSIAFVRIPAVRMIYFCLCPRKYNGICLINAVEEVQSIVYDTFVQYYVIKKEEIKVNLY 404

The following BLAST results are available for this feature:

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Human
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Celegans
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Fly
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Zebrafish
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Xenopus
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Mouse
BLAST of PPIP5K2_N domain-containing protein vs. UniProt/SwissProt
BLAST of PPIP5K2_N domain-containing protein vs. TrEMBL
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Cavefish
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Sea Lamprey
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Yeast
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Nematostella
BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Medaka
BLAST of PPIP5K2_N domain-containing protein vs. Planmine SMEST

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267FU33	3.038e-32	26.50	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267EYC4	6.670e-32	26.25	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267EJP5	8.374e-31	27.12	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A267GD37	1.735e-30	27.00	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A267GR50	1.296e-28	26.82	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO36791	2.188e-19	23.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO25994	2.891e-9	26.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45093	1.802e-8	19.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of PPIP5K2_N domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PPIP5K2_N domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000064344.1	0.000e+0	100.00	SMESG000064344.1	[more]
SMESG000064337.1	0.000e+0	56.94	SMESG000064337.1	[more]
SMESG000064337.1	0.000e+0	57.08	SMESG000064337.1	[more]
SMESG000064337.1	3.180e-169	55.80	SMESG000064337.1	[more]
SMESG000064337.1	3.826e-165	55.94	SMESG000064337.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016945 ID=SMED30016945|Name=PPIP5K2_N domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1626bp
CAAAATTTATTAATTTGTGCTATTATATATTTGCCAATTTTATTTTTTAA
TTTATAATTAGTTTGTAATATTAAACCACGTATTTAATTTATCCAACCTT
ATAGTTAATTAGTTGGAATGGGAGTTAATTATTCTAAATATATTCCTGAG
ATTAAAAAATTACCATCAAATGTCTGTGTTCTATATCTCAATACTTCCGC
TTTCTATGGAATTAATTTACCGGTTGAAGTAATTCATGATGTTGGTGAAG
TTTTTCGTGAAACATGGGGAAAAGAAATTCAAATTAAAACATACTGTGAT
ACAATAATGAAATTTGATTTGAAAAGTTGTTTACATTTTTTTTCTTTTCA
AAGCGATAGTGCCAAATTTAAACTTATGTTTTGCAAATTTCATAAATTAT
TCTATAAACATGGTTGGAGTCTTGTAAGTTCTCCAACACTCACGTTTTCT
GTATCGTTGTCTAGTTGGTTTTATTTCAAATATGATAATCCATTTCTATT
GCATGATAAAAAGGTTGAAAATGAGTTCTGTGCTATTGGATTATCTAATA
CGGATGGGTTTCAGTTCATTAATTTTCCTATTGAGTTGGAAAATCCAATT
ATTAATTGTATTAGACAAAATTGGACAAAAGGTACCAAAAATAAAAAGCT
TATTAAAGACACAGTAAATTTGTGGTCATTGCAATTAAACGGTTTTCCTT
GGTCTTGTTATGGAAAACAGAGTGTTGATGCAAGATATCTCGTTTTGTGT
TTGATAAGATTTATGAGCCATCATAACTGGCGGTTGGTCAATTCTACTGC
AATGAAGCAAGACGCTTCAGATACGATGTTTTTTCGATCACAATCCAATA
TGCTCAATGTGGATTGCCCAGAATCTATGCCAGAATACTATTTCATGTTA
GCTTTAATCAATCCTGGTTCTCTATCGATCCTAGGCTGTGATGCTAATCT
TGGACAATTTATCGCTAATTCTTGTGATAAATATGAAACCAAAGGCAGCA
AGCTTCTTTATACTAAACATAATTACGTGTCATTAGATTTAAATAGTAAA
GTTTGGAGCAGACGAAATGAAAAAGAAACAGAAACAAGGCGATTAATGAC
TTGTTTATTTCAGGATCTTGCAGCAATTGGATGGATACCAACTGAATCAA
TTGATTGCACAAGACATATTACAGATTTAAGCAGCATATTGTTCACCAGA
GTGCCTCCAGTTCGGATGCAATACTTTTGCCTTTGCCCTAGAAAGTATAA
TGGTATTTGTCTGATAAATGCAGAAGAAGATGTTCAGACTTTAATTTTCA
ATACTTTCGTTGAATATTATCCAATACAAAGAAATGACATAAAAAGATCT
TTTTACGGAGTAGCTTATTCAATTGATTTCAAAGGTGATGCTTTTAGAGG
TAGCAATTTACACGGCGTTATTCTATTTCAGTTAGCATTGGCAGCCATTA
TTAGTGTATTGAAAGATATTGGATGGTATCTATTAGTGTCTGCGGATACC
TCAAATGAAACTATGACAGTTGATGAAAACACCGAAATAAAATGGAGCAT
ATATGCATTATGGTTTTGCAGACCTTTGCCTACATGATTTATTTAAAATT
CTTACATAATTGCATAGATCGGAAGA

protein sequence of SMED30016945-orf-1

>SMED30016945-orf-1 ID=SMED30016945-orf-1|Name=SMED30016945-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=490bp
MGVNYSKYIPEIKKLPSNVCVLYLNTSAFYGINLPVEVIHDVGEVFRETW
GKEIQIKTYCDTIMKFDLKSCLHFFSFQSDSAKFKLMFCKFHKLFYKHGW
SLVSSPTLTFSVSLSSWFYFKYDNPFLLHDKKVENEFCAIGLSNTDGFQF
INFPIELENPIINCIRQNWTKGTKNKKLIKDTVNLWSLQLNGFPWSCYGK
QSVDARYLVLCLIRFMSHHNWRLVNSTAMKQDASDTMFFRSQSNMLNVDC
PESMPEYYFMLALINPGSLSILGCDANLGQFIANSCDKYETKGSKLLYTK
HNYVSLDLNSKVWSRRNEKETETRRLMTCLFQDLAAIGWIPTESIDCTRH
ITDLSSILFTRVPPVRMQYFCLCPRKYNGICLINAEEDVQTLIFNTFVEY
YPIQRNDIKRSFYGVAYSIDFKGDAFRGSNLHGVILFQLALAAIISVLKD
IGWYLLVSADTSNETMTVDENTEIKWSIYALWFCRPLPT*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PANTHER	PTHR38696	FAMILY NOT NAMED	coord: 134..280 coord: 250..464
None	No IPR available	TMHMM	TMhelix		coord: 435..457

Main menu

PPIP5K2_N domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

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