Protein kinase domain-containing protein

Overview
NameProtein kinase domain-containing protein
Smed IDSMED30016907
Length (bp)2947
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein kinase domain-containing protein (SMED30016907) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase domain-containing protein (SMED30016907) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase domain-containing protein (SMED30016907) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase domain-containing protein (SMED30016907) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016907

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30016907h1SMcG0012236 dd_Smed_v4_6544_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30016907h1SMcG0012236 dd_Smed_v4_6544_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30016907h1SMcG0012236 dd_Smed_v4_6544_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30016907h1SMcG0012236 dd_Smed_v4_6544_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016907h1SMcG0012236 Contig39992newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016907h1SMcG0012236 Contig39992uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016907h1SMcG0012236 Contig39024newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016907h1SMcG0012236 Contig39024uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: DSTYK (dual serine/threonine and tyrosine protein kinase [Source:HGNC Symbol;Acc:HGNC:29043])

HSP 1 Score: 118.242 bits (295), Expect = 2.508e-26
Identity = 88/356 (24.72%), Postives = 166/356 (46.63%), Query Frame = 2 
Query: 1862 EWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSD----DGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            EWK   A+E ++      LA+ +C          H+ F  ++       S  ++K      ++R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G S  D     G SI +   +M+   RD Y      ++++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ WQLM  CW   P  RP
Sbjct:  563 EWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLRVRK---DHAPRLARLSLESCSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHG-SVIDYNYGGGSSIAVLL-IMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYICSGSVKLPEA------FERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRP 897
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MATK (megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906])

HSP 1 Score: 110.923 bits (276), Expect = 8.076e-25
Identity = 72/254 (28.35%), Postives = 130/254 (51.18%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM----KSNLRDYINYNVISMKNKIKI---AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  HEN++ +LG+         Q  Y +M    K NL +++     ++ N  ++   ++ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE +K  +FT K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P +    P  +  LMS CW   P  RP
Sbjct:  191 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKMQHENLVRLLGVILH------QGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPPE--GCPGPVHVLMSSCWEAEPARRP 428
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MATK (megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906])

HSP 1 Score: 111.309 bits (277), Expect = 8.502e-25
Identity = 72/262 (27.48%), Postives = 130/262 (49.62%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM----KSNLRDYINYNVISMKNKIKI---AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINEL 2878
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  HEN++ +LG+         Q  Y +M    K NL +++     ++ N  ++   ++ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE     FT K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P +    P  +  LMS CW   P  RP    +  +L
Sbjct:  232 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKMQHENLVRLLGVILH------QGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGFTSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPPE--GCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 477
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MATK (megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906])

HSP 1 Score: 110.923 bits (276), Expect = 1.218e-24
Identity = 73/263 (27.76%), Postives = 133/263 (50.57%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM----KSNLRDYINYNVISMKNKIKI---AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINEL 2878
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  HEN++ +LG+         Q  Y +M    K NL +++     ++ N  ++   ++ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE +K  +FT K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P +    P  +  LMS CW   P  RP    +  +L
Sbjct:  233 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKMQHENLVRLLGVILH------QGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPPE--GCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 479
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MATK (megakaryocyte-associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6906])

HSP 1 Score: 110.923 bits (276), Expect = 1.218e-24
Identity = 73/263 (27.76%), Postives = 133/263 (50.57%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM----KSNLRDYINYNVISMKNKIKI---AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINEL 2878
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  HEN++ +LG+         Q  Y +M    K NL +++     ++ N  ++   ++ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE +K  +FT K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P +    P  +  LMS CW   P  RP    +  +L
Sbjct:  233 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKMQHENLVRLLGVILH------QGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPPE--GCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 479
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: dlk-1 (Mitogen-activated protein kinase kinase kinase dlk-1 [Source:UniProtKB/Swiss-Prot;Acc:O01700])

HSP 1 Score: 98.5969 bits (244), Expect = 5.516e-21
Identity = 61/193 (31.61%), Postives = 104/193 (53.89%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI-NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC------KSMVIAFYNERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLF 2671
            F+ +S+ + +G G+Q  VF+G   N  + +K++     T      E+ H     H+NI+  LG+        I + Y   K  L   + + N I+ +   +   EIA+G+HYLH+ +VIH+DLK PNILIS+ DS+ I D+G         S +++F        +APE +K +   +K+D+Y++G++LW + 
Sbjct:  132 FDAISELEWLGSGSQGAVFRGQLENRTVAVKKVNQLKET------EIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEY-CSKGQLCTVLKSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFCGTVS--WMAPEMIKKQPCNEKVDVYSFGVVLWEML 315
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: dlk-1 (Mitogen-activated protein kinase kinase kinase dlk-1 [Source:UniProtKB/Swiss-Prot;Acc:O01700])

HSP 1 Score: 98.2117 bits (243), Expect = 1.431e-20
Identity = 61/193 (31.61%), Postives = 104/193 (53.89%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI-NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC------KSMVIAFYNERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLF 2671
            F+ +S+ + +G G+Q  VF+G   N  + +K++     T      E+ H     H+NI+  LG+        I + Y   K  L   + + N I+ +   +   EIA+G+HYLH+ +VIH+DLK PNILIS+ DS+ I D+G         S +++F        +APE +K +   +K+D+Y++G++LW + 
Sbjct:   59 FDAISELEWLGSGSQGAVFRGQLENRTVAVKKVNQLKET------EIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEY-CSKGQLCTVLKSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFCG--TVSWMAPEMIKKQPCNEKVDVYSFGVVLWEML 242
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: dlk-1 (Mitogen-activated protein kinase kinase kinase dlk-1 [Source:UniProtKB/Swiss-Prot;Acc:O01700])

HSP 1 Score: 98.2117 bits (243), Expect = 1.462e-20
Identity = 61/193 (31.61%), Postives = 104/193 (53.89%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI-NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC------KSMVIAFYNERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLF 2671
            F+ +S+ + +G G+Q  VF+G   N  + +K++     T      E+ H     H+NI+  LG+        I + Y   K  L   + + N I+ +   +   EIA+G+HYLH+ +VIH+DLK PNILIS+ DS+ I D+G         S +++F        +APE +K +   +K+D+Y++G++LW + 
Sbjct:  132 FDAISELEWLGSGSQGAVFRGQLENRTVAVKKVNQLKET------EIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEY-CSKGQLCTVLKSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFCGTVS--WMAPEMIKKQPCNEKVDVYSFGVVLWEML 315
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: dlk-1 (Mitogen-activated protein kinase kinase kinase dlk-1 [Source:UniProtKB/Swiss-Prot;Acc:O01700])

HSP 1 Score: 98.2117 bits (243), Expect = 1.503e-20
Identity = 61/193 (31.61%), Postives = 104/193 (53.89%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI-NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC------KSMVIAFYNERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLF 2671
            F+ +S+ + +G G+Q  VF+G   N  + +K++     T      E+ H     H+NI+  LG+        I + Y   K  L   + + N I+ +   +   EIA+G+HYLH+ +VIH+DLK PNILIS+ DS+ I D+G         S +++F        +APE +K +   +K+D+Y++G++LW + 
Sbjct:  132 FDAISELEWLGSGSQGAVFRGQLENRTVAVKKVNQLKET------EIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEY-CSKGQLCTVLKSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFCGTVS--WMAPEMIKKQPCNEKVDVYSFGVVLWEML 315
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: ZK622.1 (Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;Acc:Q23554])

HSP 1 Score: 94.3597 bits (233), Expect = 4.442e-20
Identity = 92/348 (26.44%), Postives = 159/348 (45.69%), Query Frame = 2 
Query: 1898 KCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNF--IKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEG-KYKFEYVSKTDMIGKGAQSEVFKG-IYNNAEIVIKEIKLN--------VYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFY-------NERMPIH-VAPEVKMKE-FTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQM-KPEKINKFPDKIWQLMSECWSNHPDDRPDTDTI 2866
            KC H  L E+      ED  I        +I E  F  +   V TL   R  +  N P    L LN +N +  + + + +    M+G+GA   V+K   Y   E  +  +K+N           ++++ KE     ++ H N++   G+    +   I +   L      D       N +S+++K+K + + ++GL YLH+   IH+D+   N L+  N  V I+D+G  K +    +         ++PI  +APEV +   +T K D+Y++GILLW +F   G  P   + L  + Q V       N ++M  P+++  F   I  ++S+CW  +P+DR + + I
Sbjct:   76 KCHHWQLQEK------EDGSI--------VIEERKFESVLDMVTTLRMKRLPVSANCP---ALLLNPINKQDWELRHDQIKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKE--PIMLVMELASQGALDSFLKNEKNNVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHKN-VVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGILLWEIFM-DGAIPYPGMKLAEVKQKV------KNGYRMDAPDRMPAFVRNI--MISQCWPQNPEDRGNMNEI 394
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0343995)

HSP 1 Score: 95.5153 bits (236), Expect = 6.939e-20
Identity = 68/246 (27.64%), Postives = 124/246 (50.41%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNA-EIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFY----NERMPIH-VAPEVKM-KEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            +G+G   EVF G + N+ ++ +K ++    +     +E     +F H  ++ +  +   ++   I   Y + K +L D++   +   +  ++ I IA ++A G+ YL  +++IH+DL   N+LI  N+   I D+G  + +    Y      R P+   APE  +  +F+ K D+++YGILL  LF   G+ P   +     ++ V EN   +  F+M     + FPD I+QL+ +CW   P+ RP
Sbjct:  291 LGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEY-MSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFT-YGQVPYPGM----HSREVIEN--IERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRP 528
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100508)

HSP 1 Score: 95.1301 bits (235), Expect = 7.219e-20
Identity = 68/246 (27.64%), Postives = 124/246 (50.41%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNA-EIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFY----NERMPIH-VAPEVKM-KEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            +G+G   EVF G + N+ ++ +K ++    +     +E     +F H  ++ +  +   ++   I   Y + K +L D++   +   +  ++ I IA ++A G+ YL  +++IH+DL   N+LI  N+   I D+G  + +    Y      R P+   APE  +  +F+ K D+++YGILL  LF   G+ P   +     ++ V EN   +  F+M     + FPD I+QL+ +CW   P+ RP
Sbjct:  290 LGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEY-MSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFT-YGQVPYPGM----HSREVIEN--IERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRP 527
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100505)

HSP 1 Score: 95.1301 bits (235), Expect = 7.219e-20
Identity = 68/246 (27.64%), Postives = 124/246 (50.41%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNA-EIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFY----NERMPIH-VAPEVKM-KEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            +G+G   EVF G + N+ ++ +K ++    +     +E     +F H  ++ +  +   ++   I   Y + K +L D++   +   +  ++ I IA ++A G+ YL  +++IH+DL   N+LI  N+   I D+G  + +    Y      R P+   APE  +  +F+ K D+++YGILL  LF   G+ P   +     ++ V EN   +  F+M     + FPD I+QL+ +CW   P+ RP
Sbjct:  290 LGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEY-MSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFT-YGQVPYPGM----HSREVIEN--IERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRP 527
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100504)

HSP 1 Score: 95.1301 bits (235), Expect = 7.219e-20
Identity = 68/246 (27.64%), Postives = 124/246 (50.41%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNA-EIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFY----NERMPIH-VAPEVKM-KEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            +G+G   EVF G + N+ ++ +K ++    +     +E     +F H  ++ +  +   ++   I   Y + K +L D++   +   +  ++ I IA ++A G+ YL  +++IH+DL   N+LI  N+   I D+G  + +    Y      R P+   APE  +  +F+ K D+++YGILL  LF   G+ P   +     ++ V EN   +  F+M     + FPD I+QL+ +CW   P+ RP
Sbjct:  290 LGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEY-MSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFT-YGQVPYPGM----HSREVIEN--IERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRP 527
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0304990)

HSP 1 Score: 95.1301 bits (235), Expect = 7.219e-20
Identity = 68/246 (27.64%), Postives = 124/246 (50.41%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNA-EIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFY----NERMPIH-VAPEVKM-KEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            +G+G   EVF G + N+ ++ +K ++    +     +E     +F H  ++ +  +   ++   I   Y + K +L D++   +   +  ++ I IA ++A G+ YL  +++IH+DL   N+LI  N+   I D+G  + +    Y      R P+   APE  +  +F+ K D+++YGILL  LF   G+ P   +     ++ V EN   +  F+M     + FPD I+QL+ +CW   P+ RP
Sbjct:  290 LGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEY-MSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFT-YGQVPYPGM----HSREVIEN--IERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRP 527
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:402922])

HSP 1 Score: 118.627 bits (296), Expect = 1.009e-26
Identity = 95/346 (27.46%), Postives = 164/346 (47.40%), Query Frame = 2 
Query: 1862 EWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI--ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE-----GKYKFEYVSKTDMIGKGAQSEVFKGIYNNA--EIVIKEIKLNVYTLDNIAKEVFHSHRF--SHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKS-MVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            EWK   A++ ++      LA+ +C          H+ F  ++  + E +  + E      +R +  ++APR   L L   ++      GK K          G     + + G +  A   +V  + K      +++A E FH  R    HE ++ + G  I  S  G S      +M+   RD Y      +S+K ++ IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WYL  GS + P+      + +Q +W N         +PE++  F ++ WQLM  CW+  P  RP
Sbjct:  525 EWKRKVAQDAIESLSAAKLAKSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRK-DHAPRLARLSLESRSLRDILLHGKPKLGRELGRGQYGVVYLCDSWAGRHPCALKSVVPPDDK----HWNDLALE-FHYTRSLPKHERLVNLHGSVIDHSYSGGSSIAVLLIMERLHRDLYTGLKAGLSLKERLLIALDVVEGIRFLHSQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYLCSGSVKLPEAFEKCASKDQ-LWTNV----KKGCRPERLPVFDEECWQLMEACWNGDPSQRP 859
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:402922])

HSP 1 Score: 118.627 bits (296), Expect = 1.127e-26
Identity = 95/346 (27.46%), Postives = 164/346 (47.40%), Query Frame = 2 
Query: 1862 EWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI--ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE-----GKYKFEYVSKTDMIGKGAQSEVFKGIYNNA--EIVIKEIKLNVYTLDNIAKEVFHSHRF--SHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKS-MVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            EWK   A++ ++      LA+ +C          H+ F  ++  + E +  + E      +R +  ++APR   L L   ++      GK K          G     + + G +  A   +V  + K      +++A E FH  R    HE ++ + G  I  S  G S      +M+   RD Y      +S+K ++ IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WYL  GS + P+      + +Q +W N         +PE++  F ++ WQLM  CW+  P  RP
Sbjct:  497 EWKRKVAQDAIESLSAAKLAKSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRK-DHAPRLARLSLESRSLRDILLHGKPKLGRELGRGQYGVVYLCDSWAGRHPCALKSVVPPDDK----HWNDLALE-FHYTRSLPKHERLVNLHGSVIDHSYSGGSSIAVLLIMERLHRDLYTGLKAGLSLKERLLIALDVVEGIRFLHSQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYLCSGSVKLPEAFEKCASKDQ-LWTNV----KKGCRPERLPVFDEECWQLMEACWNGDPSQRP 831
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-070705-183])

HSP 1 Score: 113.62 bits (283), Expect = 4.760e-26
Identity = 70/244 (28.69%), Postives = 131/244 (53.69%), Query Frame = 2 
Query: 2138 DMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM-KSNLRDYINYN---VISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            ++IG+G    VF G Y    + +K IK +V T     +E        H+N++ +LG+   +    + I   LM K NL +++       +S+   ++ A+++ EG+ +L  ++++H+DL   NIL+S +    ISD+G  +   +A  N ++P+   APE +K K+F+ + D+++YG+LLW +F   GR+P   +   T+N+V       +  ++M P   ++ P  ++ +M+ CW   P  RP
Sbjct:  197 EIIGEGEFGAVFAGEYTGQRVAVKIIKCDV-TAQAFLEETSVMTNLHHKNLVPLLGVILHN---GLHIVTELMTKGNLVNFLRSRGRFAVSVIQLLRFALDVCEGMEHLESKKLLHRDLAGRNILVSEDGVAKISDFGLARVGSMAVDNSKLPVKWTAPEALKNKKFSTQSDVWSYGVLLWEIFS-YGRQPYPKM---TVNEV---KECVEKGYRMDPP--DECPADVYSIMTSCWQTEPKKRP 427
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-070705-183])

HSP 1 Score: 113.235 bits (282), Expect = 5.984e-26
Identity = 70/244 (28.69%), Postives = 131/244 (53.69%), Query Frame = 2 
Query: 2138 DMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM-KSNLRDYINYN---VISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            ++IG+G    VF G Y    + +K IK +V T     +E        H+N++ +LG+   +    + I   LM K NL +++       +S+   ++ A+++ EG+ +L  ++++H+DL   NIL+S +    ISD+G  +   +A  N ++P+   APE +K K+F+ + D+++YG+LLW +F   GR+P   +   T+N+V       +  ++M P   ++ P  ++ +M+ CW   P  RP
Sbjct:  194 EIIGEGEFGAVFAGEYTGQRVAVKIIKCDV-TAQAFLEETSVMTNLHHKNLVPLLGVILHN---GLHIVTELMTKGNLVNFLRSRGRFAVSVIQLLRFALDVCEGMEHLESKKLLHRDLAGRNILVSEDGVAKISDFGLARVGSMAVDNSKLPVKWTAPEALKNKKFSTQSDVWSYGVLLWEIFS-YGRQPYPKM---TVNEV---KECVEKGYRMDPP--DECPADVYSIMTSCWQTEPKKRP 424
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:ZFIN;Acc:ZDB-GENE-040426-2436])

HSP 1 Score: 107.071 bits (266), Expect = 3.953e-23
Identity = 80/270 (29.63%), Postives = 133/270 (49.26%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKI------AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC-----KSMVIAFYNERMPIHVAPEV-KMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQ--VVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE +S+   +G GAQ  VF G ++  E+ +K+++      D    E+ H  +  H NI+T  G+        I + Y   +  L     Y V+    KI        AM IA G++YLH  ++IH+DLK PN+LI+ +D V ISD+G       KS  ++F        +APEV + +  ++K+DI+++G++LW +         G I  K ++   ++W   + +N  Q+     +  PD    L+ +CW+  P +RP    I+  L I
Sbjct:  146 FEEISELQWVGSGAQGAVFLGKFHGEEVAVKKVR------DIKETEIKHLRKLKHPNIITFKGVCTQAPCYCILMEY-CAQGQL-----YEVLRAGRKITPCLLVDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITHDDLVKISDFGTSKELRDKSTKMSFAGTVA--WMAPEVIRNEPVSEKVDIWSFGVVLWEML-------TGEIPYKDVDSSAIIW--GVGNNSLQLP--LPDSCPDGFKILLRQCWNCKPRNRPSFRQILLHLDI 390
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205])

HSP 1 Score: 120.168 bits (300), Expect = 4.716e-27
Identity = 85/356 (23.88%), Postives = 168/356 (47.19%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKS-DDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA+ +C    +  +  H+ F  ++    +  S  ++K      ++R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  S   G SI +     + +   Y+     +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+       I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ W+LM  CW+  P  RP
Sbjct:  477 TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASLKQLEVGHSGRLEKTNDLWLRVRK---DHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDVYAFGILFWYICSGSVKLPEA------FEKCASKDHLWNNVRKGARPERLAIFDEECWKLMEACWNGDPSQRP 813
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205])

HSP 1 Score: 120.168 bits (300), Expect = 5.237e-27
Identity = 85/356 (23.88%), Postives = 168/356 (47.19%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKS-DDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA+ +C    +  +  H+ F  ++    +  S  ++K      ++R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  S   G SI +     + +   Y+     +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+       I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ W+LM  CW+  P  RP
Sbjct:  473 TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASLKQLEVGHSGRLEKTNDLWLRVRK---DHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDVYAFGILFWYICSGSVKLPEA------FEKCASKDHLWNNVRKGARPERLAIFDEECWKLMEACWNGDPSQRP 809
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205])

HSP 1 Score: 120.168 bits (300), Expect = 5.377e-27
Identity = 85/356 (23.88%), Postives = 168/356 (47.19%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKS-DDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA+ +C    +  +  H+ F  ++    +  S  ++K      ++R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  S   G SI +     + +   Y+     +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+       I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ W+LM  CW+  P  RP
Sbjct:  541 TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASLKQLEVGHSGRLEKTNDLWLRVRK---DHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDVYAFGILFWYICSGSVKLPEA------FEKCASKDHLWNNVRKGARPERLAIFDEECWKLMEACWNGDPSQRP 877
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205])

HSP 1 Score: 120.168 bits (300), Expect = 5.406e-27
Identity = 85/356 (23.88%), Postives = 168/356 (47.19%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKS-DDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA+ +C    +  +  H+ F  ++    +  S  ++K      ++R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  S   G SI +     + +   Y+     +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+       I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ W+LM  CW+  P  RP
Sbjct:  557 TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASLKQLEVGHSGRLEKTNDLWLRVRK---DHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDVYAFGILFWYICSGSVKLPEA------FEKCASKDHLWNNVRKGARPERLAIFDEECWKLMEACWNGDPSQRP 893
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:493205])

HSP 1 Score: 120.168 bits (300), Expect = 5.416e-27
Identity = 85/356 (23.88%), Postives = 168/356 (47.19%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKS-DDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA+ +C    +  +  H+ F  ++    +  S  ++K      ++R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  S   G SI +     + +   Y+     +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+       I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ W+LM  CW+  P  RP
Sbjct:  552 TPEWKRRVAQDAIESLSASKLAKSICSQFCKRLKSSHEAFAASLKQLEVGHSGRLEKTNDLWLRVRK---DHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIALDVVEGIRFLHNQGLVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDVYAFGILFWYICSGSVKLPEA------FEKCASKDHLWNNVRKGARPERLAIFDEECWKLMEACWNGDPSQRP 888
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Dstyk (dual serine/threonine and tyrosine protein kinase [Source:MGI Symbol;Acc:MGI:1925064])

HSP 1 Score: 117.472 bits (293), Expect = 3.302e-26
Identity = 87/354 (24.58%), Postives = 163/354 (46.05%), Query Frame = 2 
Query: 1862 EWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            EWK   A+E +       LA+ +C          H+ F  ++       S  ++K      K+R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  +  G S      +M+   RD Y      ++++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ WQLM  CW   P  RP
Sbjct:  561 EWKRKVAQEAIDSLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRK---DHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYICSGSIKLPEA------FERCASKDHLWNNVRRGTRPERLPVFDEECWQLMEACWDGDPLKRP 895
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Matk (megakaryocyte-associated tyrosine kinase [Source:MGI Symbol;Acc:MGI:99259])

HSP 1 Score: 110.538 bits (275), Expect = 6.471e-25
Identity = 71/259 (27.41%), Postives = 131/259 (50.58%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYN---VISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINEL 2878
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  H N++ +LG+     G  I +   + K NL +++      ++S    ++ A+ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE +K   F+ K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P   +  P  +  LM  CW   P  RP    I+ +L
Sbjct:  191 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKLQHRNLVRLLGVI-LHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPP--DGCPGSVHTLMGSCWEAEPARRPPFRKIVEKL 437
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Matk (megakaryocyte-associated tyrosine kinase [Source:MGI Symbol;Acc:MGI:99259])

HSP 1 Score: 110.538 bits (275), Expect = 6.471e-25
Identity = 71/259 (27.41%), Postives = 131/259 (50.58%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYN---VISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINEL 2878
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  H N++ +LG+     G  I +   + K NL +++      ++S    ++ A+ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE +K   F+ K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P   +  P  +  LM  CW   P  RP    I+ +L
Sbjct:  191 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKLQHRNLVRLLGVI-LHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPP--DGCPGSVHTLMGSCWEAEPARRPPFRKIVEKL 437
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Matk (megakaryocyte-associated tyrosine kinase [Source:MGI Symbol;Acc:MGI:99259])

HSP 1 Score: 110.538 bits (275), Expect = 6.701e-25
Identity = 71/259 (27.41%), Postives = 131/259 (50.58%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYN---VISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINEL 2878
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  H N++ +LG+     G  I +   + K NL +++      ++S    ++ A+ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE +K   F+ K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P   +  P  +  LM  CW   P  RP    I+ +L
Sbjct:  190 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKLQHRNLVRLLGVI-LHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPP--DGCPGSVHTLMGSCWEAEPARRPPFRKIVEKL 436
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Matk (megakaryocyte-associated tyrosine kinase [Source:MGI Symbol;Acc:MGI:99259])

HSP 1 Score: 110.538 bits (275), Expect = 6.701e-25
Identity = 71/259 (27.41%), Postives = 131/259 (50.58%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYN---VISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINEL 2878
             ++++    IG+G    V +G Y   ++ +K IK +V T      E     +  H N++ +LG+     G  I +   + K NL +++      ++S    ++ A+ +AEG+ YL  ++++H+DL   NIL+S +    +SD+G  K+      + R+P+   APE +K   F+ K D++++G+LLW +F   GR P   + LK +++ V      +  ++M+P   +  P  +  LM  CW   P  RP    I+ +L
Sbjct:  190 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDV-TAQAFLDETAVMTKLQHRNLVRLLGVI-LHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFS-YGRAPYPKMSLKEVSEAV------EKGYRMEPP--DGCPGSVHTLMGSCWEAEPARRPPFRKIVEKL 436
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|A2CI35|DUSTY_STRPU (Dual serine/threonine and tyrosine protein kinase OS=Strongylocentrotus purpuratus OX=7668 GN=DSTYK PE=2 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 4.953e-28
Identity = 105/424 (24.76%), Postives = 196/424 (46.23%), Query Frame = 2 
Query: 1664 KTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILN-NAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFK-----GIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHR--FSHENIMTILGISKSDDG-------KSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKS-MVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDN-DFQMKPEKIN-KFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            +TS  ++L +ILN  Y+++     S+     +++E M     S+K F +          +V+    EWK   A+  +   D   LA+ +C          H++F  ++          +   E+ R K+    APR   L L   ++     +        IG+G    V+      G+ + A  V   +  +    +++A E FH  R    H+ I+ ++G S  D G        ++ +    M+ +L   I  N + +  ++ +A+++AEG+ YLH   ++H+D+KL N+L+  +D   I+D GFCK   +++      PIH+APE+   ++   +D YA+GILLWY+  G  + P+         Q   ++ ++ +    ++PE++  +F D  W LM   W+  P +RP    + ++LQ
Sbjct:  522 ETSTTVALRQILNAAYQVEVSVRTSSS-VVRIIWERMKEFFQSIKPFKT--------PTRVDT---EWKRKVAQTMINNLDESKLAKSICSQFRSRLNNSHESFSTSLRQLEQKHSGRLEKTEEQRMKVRKVYAPRLARLALESTSLRDMVLYGMPKLEREIGRGQYGVVYSCRSWGGVTHCA--VKSVVPPDDKHWNDLAME-FHYTRSIAEHDRIVAVIG-SVIDHGYGGMGCSPAVLLLMERMQRDLHTAIKAN-MELPERLHVALDVAEGVRYLHSLGLVHRDIKLKNVLLDKHDRGKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDTYAFGILLWYVCAGHVKLPQA------FEQCANKDHLWTSVKKGVRPERLRPQFDDASWNLMKSSWAGEPSERPLLGEVQSKLQ 922
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4TVR5|DUSTY_BOVIN (Dual serine/threonine and tyrosine protein kinase OS=Bos taurus OX=9913 GN=DSTYK PE=2 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 9.098e-27
Identity = 88/354 (24.86%), Postives = 164/354 (46.33%), Query Frame = 2 
Query: 1862 EWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            EWK   A+E ++      LA+ +C          H+ F  ++       S  ++K      K+R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  S  G S      +M+   RD Y      ++++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P+         +   ++ +++N  +  +PE++  F ++ WQLM  CW   P  RP
Sbjct:  562 EWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRK---DHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDSWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYSYGGGSSIAVLLIMERLHRDLYTGLKAGLALETRLQIALDVVEGIRFLHSQGLVHRDVKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYICSGSVKLPEA------FERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPSQRP 896
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q67E01|DUSTY_XENLA (Dual serine/threonine and tyrosine protein kinase OS=Xenopus laevis OX=8355 GN=dstyk PE=2 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 9.666e-27
Identity = 86/356 (24.16%), Postives = 168/356 (47.19%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI----ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIE--------------GKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKS-DDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA+ +C    +  +  H+ F  ++    +  S  ++K      ++R    ++APR   L L   +++              G+ ++  V   D  G G      K +    E    ++ L  + + ++ K         HE ++ + G  I  S   G SI +     + +   Y+     +S++ +++IA+++ EG+ +LH Q V+H+D+KL N+L+       I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WY+  GS + P      +   +   ++ +++N  +  +PE++  F ++ W+LM  CW+  P  RP
Sbjct:  550 TPEWKRRVAQDAIETLSASKLAKSICSQFCKRLKSSHEAFAASLKQLEVGHSGRLEKTNDLWLRVRK---DHAPRLARLSLESRSLQDVLLHGKPRIGRELGRGQYGVVYLCDSWG-GHFPCALKSVVPPDEKHWNDLALEFHYMRSLPK---------HERLVDLHGSVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIALDVVEGIRFLHNQGVVHRDIKLKNVLLDKKHRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDVYAFGILFWYICSGSVKLP------EAFEKCASKDHLWNNVRKGARPERLTIFDEECWKLMEACWNGDPSQRP 886
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4VSN2|DUSTY_TAKRU (Dual serine/threonine and tyrosine protein kinase OS=Takifugu rubripes OX=31033 GN=dstyk PE=2 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 1.025e-26
Identity = 100/365 (27.40%), Postives = 169/365 (46.30%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKIL----NNAPRFYPLFLNI-----VNIEGKYKFEYVSKTDMIGKGAQSEVF-----KGIYNNA--EIVIKEIKLNVYTLDNIAKEVFHSHRF--SHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKS-MVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
             PEWK   A++ ++      LA  +C          H+ F  ++       ++    LE+     L    ++APR   L L       V + GK K         +G+G    V+      G Y  A   +V  + K      +++A E FH  R    HE ++ + G  I  +  G S      +M+   RD Y      +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WYL  GS + P+      + +Q +W N         +PE++  F ++ WQLM  CW+  P  RP    +   LQ
Sbjct:  554 TPEWKRKVAQDAIESLSAAKLARSICSQFRTRLNSSHEAFAASL---RQLEERHTGRLERTEDLWLRVRKDHAPRLARLSLESRSLRDVLLHGKPKL-----GRELGRGQYGVVYLCDNWGGHYPCALKSVVPPDDK----HWNDLALE-FHYTRTLPKHERLVDLHGSVIDHTYAGGSSIAVLLIMERLHRDLYTGLKAGLSLQERLQIALDVVEGIRFLHNQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYLCAGSVKLPEAFEKCSSKDQ-LWNNV----KKGARPERLPCFDEECWQLMEACWNGDPSQRPLLGIVEPSLQ 900
[Close]
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4VSN3|DUSTY_TETNG (Dual serine/threonine and tyrosine protein kinase OS=Tetraodon nigroviridis OX=99883 GN=dstyk PE=2 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 1.958e-26
Identity = 95/352 (26.99%), Postives = 165/352 (46.88%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKIL----NNAPRFYPLFLNI-----VNIEGKYKFEYVSKTDMIGKGAQSEVFK----GIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRF--SHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA  +C          H+ F  ++       ++    LE+     L    ++APR   L L       V + GK K         +G+G    V+     G +N   +    +  +    +++A E FH  R    HE ++ + G  I  +  G S      +M+   RD Y      +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WYL  GS + P+      + +Q +W N         +PE++  F ++ WQLM  CW+  P  RP
Sbjct:  554 TPEWKRKVAQDAIESLSAAKLARSICSQFRTRLYSSHEAFAASL---RQLEERHTGRLERTEDLWLRVRKDHAPRLARLSLESRSLRDVVLHGKPKL-----GRELGRGQYGVVYLCDSWGGHNPCALK-SVVPPDDKHWNDLALE-FHYTRTLPKHERLVDLHGSVIDHTYAGGSSIAVLLIMERLHRDLYTGLKAGLSLQERLQIALDVVEGIRFLHSQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYLCAGSVKLPEAFEKCSSKDQ-LWNNV----RKGARPERLPCFDEECWQLMEACWNGDPSQRP 890
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267FM29 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021056g2 PE=4 SV=1)

HSP 1 Score: 297.745 bits (761), Expect = 1.288e-82
Identity = 259/944 (27.44%), Postives = 451/944 (47.78%), Query Frame = 2 
Query:  188 IYKYRQSREELISSINETIKLFDEFLTEPI-PEIIETFDRKSLIDLKTELGERSGPKMQEI-ELIRENISLEN----PVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLD-GEDLDSETANPIA-ISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQS--------SQEITYHLEQFQKFQRDFETILSI-------YFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSI---QIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSN-----GLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFE--YVSKTDMIGKGAQSEVFKGIYNNAE--IVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGI----SKSDDGK-SIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSN-DSVCISDYGFCKSMVIAFYNERM---PIHVAPE-VKMKEFTKKIDIYAYGILLWYLFEGSG-REPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            I ++R +R+ +   ++ T +L  E  ++ + PE    F  K    LK E      P  Q++ +L R N +  +    P II++GQ K+GKS+FIN LL    V QS   CT RVTR++YS+  ++ +    G  I    +    ++    +KL   +R+N   IS  V+ G+K +FL  GIDIIDSPG+     L  L    + + LP++IYVID  +G+      DL  +       E+ Y +T +D  +D + E   P   I + K E  F KLQ   +I S  +T  +C  F   S   +    +K+           E    +E   K+ R FE + +         FRN I  S   L   Q  + T  +++A N K    +  + + QIK +E+E++ + K  +  ++ +L+ +       +   I++ +    Y  S+    + +  I  +   VD+    I   +I    + LK        Q + +         +K     YE       +Y + L++ L   Y L          ++  +   +NV++  +K F+       GL + ++     +++ +WK  QA++YL       L E +  SL E FE +H+ F  NI S    ++  +   EK R++I    PR   L +  +++  KYK+    +     +G GAQ EVF+ +  + E  +  K I  +  +LD+IA EV+HS    H+N++ ++G+    SK D+ + +++I+  LM  +  + +  + + ++ ++KI +E+A+ L +LH  E+IH+D+KL N+L+S +   V +SD+G  KS    F N  +   PI++APE V+ + +    D+++ GI LWYLFEG+G R P+    + ++  ++   ++       +P ++    D++W LM  CWS  PD RP     +  LQ
Sbjct:   18 IAEFRSNRDLIKEHLDTTQRLLTESFSKALSPE----FSAKLQESLKFE------PVRQKVNQLYRGNQTGSSDSSKPCIIIVGQTKSGKSSFINELLGGTFVAQSQSPCTARVTRLTYSDRIYVLVRSKTGEQIGDVQYLEKPTIEEDLVKLKDEDRENDELISSTVEAGIKCEFLRHGIDIIDSPGLNENSSLDSLTLGAIDSFLPIIIYVIDSNSGITVAVQKDLTTIKKTVLGAEVFYLVTKMDVSKDTEQEANRPAQEIEEEKAERVFSKLQRLGYI-SPNETKEKCNKFLCVSCWEVRRFRRKKELMIKKNKLDPEALKEMEN-SKWVRRFEEVKTRILKFAQDQFRNLIVSSGGGLRRIQSEILTLFMDKATNIKESNLRKKKALYQIKSLEQEIHQQSKSIVEKNRDELLRQAGLFFAERKPLILDEVRALKYSESVISADMSQKDI--EKKCVDEIHALINDRIIASFCDFLKDGALRLCLQEFDD---------LKQKVAEYEKDVEQTPAYQV-LKKTLLEGYSL---------SSKDFLLGPLNVIIFRIKHFVRQMVRNPGLVLSIS---TPIQDQKWKEYQAEKYLGTISKENLVECLITSLKEWFEKQHREFLDNIASSEQLVESCMKLTEKERSEIKTLYPRVARLHMLTMDVISKYKYRGFRIDTEGNLGSGAQGEVFRVLNESGEPALAAKRIVSDEPSLDDIATEVYHSSVLEHDNLVHVVGVRLHKSKPDEKRWTVEIYMELMCCDAWNLMQRHRLPVRQRLKIGLELAKALQFLHSSELIHRDVKLANVLVSEDLRQVKLSDFGLVKST--GFVNRTLVGTPIYLAPELVRGESYHTSADVFSLGIALWYLFEGTGKRHPEYVEIMPSVGAILLAGAL-----DCRPTRLPNMSDQLWDLMESCWSGTPDSRPTAKAAVESLQ 918
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A2B4SY00 (Dual serine/threonine and tyrosine protein kinase OS=Stylophora pistillata OX=50429 GN=Dstyk PE=4 SV=1)

HSP 1 Score: 279.256 bits (713), Expect = 7.325e-76
Identity = 231/877 (26.34%), Postives = 419/877 (47.78%), Query Frame = 2 
Query:  395 ENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIE--KKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDL------DSETANPIA-----------ISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIE--ASQKQ----SSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKG--DLINRLINRLKSQSKEIINPIIDTIYP-NSIQIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKT-----FVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGL--FMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNAE------IVIKEIKLNV-YTLDNIAKEVFHSHRFSHENIMTILGI---SKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQIF 2887
            + P +I +GQ   GKS+ IN LL    +P S    T R+ R+ ++E  +  L+D++G+ +E  K   +    +  K I+L   +R +P ++  +V+ G+   FL+ G+ IIDSPG    + L  L K  ++N L  VIYV+DG     + D   L E+ S   ++ I + ++ L+ ED       D E     A           + +RK    + +L  +   PS      +   FHG S   + +  AS+K+    S  E T ++E F++FQ   +       R ++   C+TL+          I +A   K    + ++ +    + E++++  I   + D K   D+ + L + ++    +I+    D  Y    + IP +G V +   V  CQ  I  +++  L+  +K      F   +LF  +   +KD + +   +I    + P     S  ++L   L  +Y+    + ++          F+  V       + N +   ++    +V V + EWK+  A E LKK D  L+A+E+  SL + F   H+ F   I    +   +     +  R  IL  AP    L +    +  ++KF + +  D+IG GAQ  VF    NN +       V+K +K+     L ++  E+ ++    H NI+ +L     S    G S+Q+    M+ +L D +  ++ SM+ +++IA+++A+ L YLH +++IH+D+K+ N+L+   ++  ++D G CK   +I+      PI++APE+  +++ K ID+YA+G++LW + EG G +P+  I    L  V+   +  DN     PEK++ FP+  WQLM +CW+  P+ RP  D+++ +L+ +
Sbjct:  100 QEPALIFVGQTNCGKSSIINELLGCKALPTSDQPSTARIVRVCHAEKPYCRLVDTNGKTLEEIKMTGKDGNRIPRKKIELKPKDRNDPTKVGAIVESGINIDFLKCGVTIIDSPGRNENEALDNLVKKQLENPLAFVIYVVDGHDLFTKQDREVLNEMTSSGNDLSIFFVVSKLEPEDRTESSDEDDEPGGHAASTKARKKGELKVQERKKTRVYERLVKNGHFPSQL-CMDENERFHGLSAWRIQQYLASKKKNPKASFDEYTDYVEAFKRFQNSLKKFAEESLRARVESVCKTLIRVLSRCLDFFIQKANVLKKGKTQILKTLGTFLREEQQVHDNIIRDLEDEKRAEDIRDLLSDAMEGAKGDILKEAGDFEYVLAELTIPSSGHVKEKAAVAHCQDQIRCMVVNKLQGEIKQRLTMMFRSRDLFVVH---LKDGMEQIQGEIAADSDIP-----SAALALGNSLLSSYE----TQITFSQRHGAAVRFIMKVSEWFYKAIRNPIDTVVKTITGEVQVGSKEWKVKVASEALKKVDPSLMAKEIVSSLKQHFCDCHQEFTSEIGKVQDLFDRGETIKDMQRETILGFAPNLALLEMLAYGVMDRFKFGFPAAGDLIGSGAQGSVF--ACNNIKTPEGRPCVVKVVKVATEEVLKDLTLELHNTRALQHSNILPVLCTVVESNPTRGLSVQLVSERMRCDLHDGLK-DIPSMRKRLEIALDVAKALQYLHGEDLIHRDVKMQNVLLDEENNAKLTDLGLCKPEGLISNSLVGTPINMAPEMIKQQYDKSIDVYAFGMMLWRVCEGQGNQPQN-INRHFLPLVMLMMNAVDNK---TPEKLDVFPEHCWQLMQKCWTQDPEARPSFDSVVRDLESY 956
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267FZS1 (Protein kinase domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014911g1 PE=4 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 8.011e-72
Identity = 250/965 (25.91%), Postives = 443/965 (45.91%), Query Frame = 2 
Query:  149 SVNKDYDTELSKCIYKYRQSREELISSINETIKLFDEFLTEPIPE-----IIETFDRKSLIDLKTEL--GERSGPKMQEIELIRENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGED-LDSETANPIA-ISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCL---------------------IEASQKQSSQ-----EITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEII-NPIIDTIYPNSIQIPENGIVNDPFIVDQCQRTIMKIL----IQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSN-GLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFE--YVSKTDMIGKGAQSEVFKGIYNNAEIVI--KEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGI-----SKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVC-ISDYGFCKSMVIAFYN-ERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGR-EPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            +V +D D  LS+ I ++  +R++L  ++ ET +  +    + +       +++     S+  L   L  G R G                 P II+ GQ K+GKS+FIN LL    V QS   CT RVTR++YS+  ++ +    G  I    +    ++    +KL   +R+N   IS  V+ G+K +FL  GIDIIDSPG+     L  L    + + LP++IYVID  +GV      DL  +       EI+Y IT +D  D L +E    +A +   K +  F KLQ   +I S   T   C  F   S  C                       E+ +K  S      E +  + QF++ +R         F+N I  +  +L      + T  +++A + K   ++  + + QIK +E E++ + K  +   +G+ + +  NR  ++ K +I + +    Y +S+ I E     D  I  +C   I  ++    I    + L+  V    F ++ +         +K+    YE       +Y + L++ L   Y L   + V     +  V  F+  + S+++  L +  +F+        V++ +WK +QA +YLK  D   L   +  S+ E F+ +H  F  ++      ++K     ++ R +I+  +P    L +N   I  +YKF    +   + +G GAQ  V+  +    E V+  K+I  N   L+ IA E ++S    H NI+ ++G      +K +   S++++  LM  +    +    +S+  ++ + ++I++ L +LH  ++IH+D+KL N+L++S  +V  +SD+G  K   +  +     PI+++PE V+ + +    DI++ GI LWYL EGSG+  P     LKT+ +V+   S    +   +P ++ +  D++WQLM  CW   P  RP    +   L+
Sbjct:   22 AVQEDRDF-LSREIKRFYANRDQLRKTLQETQEFVETRFAQNLSAEFSSLVMQNLQLDSVWQLVNRLFNGHRGGSD-----------GSSRPCIIIAGQTKSGKSSFINELLGGTFVAQSQSPCTARVTRLTYSDRIYVLVRSKTGEQIGDVQYLEKPTIEEDLVKLKDEDRENDELISSTVEAGIKCEFLRHGIDIIDSPGLNENSSLDSLTLGAIDSFLPIIIYVIDSNSGVTVAVQKDLQTIQKTASGAEILYLITKMDVADHLAAEMGREVAEMEAEKADHVFSKLQRLGYI-SKDATRQSCRKFLCVS--CWEVRRFRRKKEMIEKKMKKSKTAESGEKLMSDLVKEMENSKWVRQFEEVKRRILQFAQDQFKNLIVGAGSSLRAVHCQILTMFMDKAHDIKESNQRKKKALYQIKSLEHEIHQQSKSIVERHRGEFLAQ-ANRFFAEKKPLILDEVRSMSYSDSV-ISEGMSQRD--IEKKCIEEIHTLINDRIIATFSDFLRDNVLRTCFTDFDD---------LKEKVAEYEKDVEQTPAYQV-LKKTLLEGYSLSSKAIV-----RGSVTCFIRNIGSTLRALLKHPDIFL-----GKAVQHHKWKEHQASQYLKNIDREKLVACLVSSIGEWFDKRHSDFLHSMSYSEVLVEKSYRMTDRERKEIIKLSPIVALLHMNAFAIITRYKFRNHRLDLDNCLGSGAQGRVYTVLSPTGEPVMAAKKIVTNRAGLEEIAAEAYYSSVLEHPNIVRVVGTVLLENAKHNGQWSVELYMELMHCDALTLMEQQRLSLAKRLWLGLQISKALEFLHSSQLIHRDVKLANLLVNSEATVAKLSDFGLLKGQGLVGHTLVGTPIYLSPELVRRENYGVSTDIFSLGIALWYLVEGSGQHHPDYVTNLKTVEEVLAATS----ERGCRPNRLPEASDQLWQLMVRCWDETPAKRPTAGQVSASLE 943
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A3M6TL50 (Protein kinase domain-containing protein OS=Pocillopora damicornis OX=46731 GN=pdam_00001199 PE=4 SV=1)

HSP 1 Score: 266.159 bits (679), Expect = 2.559e-71
Identity = 221/871 (25.37%), Postives = 417/871 (47.88%), Query Frame = 2 
Query:  395 ENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIE--KKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDLDSET---------ANPI-AISQRKMELSFRK-------LQYHNFIPSSYKTYSQCPYFHGASL------KCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDL-INRLINRLKSQSKE-IINPIIDTIYP-NSIQIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPK-NGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGL--FMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFK----GIYNNAEIVIKEIKL-NVYTLDNIAKEVFHSHRFSHENIMTILGI---SKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCK-SMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQIF 2887
            + P +I +GQ   GKS+ IN LL    +P S    T R+ R+ ++E  +  L+D+ G+ +E  K   +    +  K I+L   +R +P+++  +V+ G+  +FL+ G+ IIDSPG      L  L K  +KN L  VIYV+DG     + D   L E+ S   ++ I + ++ L+ ED    +         A P+ A  +R++E+  RK       L  +   PS   + +Q   FHG S         L + + + SS+E T + + F++FQ   +       R ++   C TL+          I +A   K   K+ ++ ++ + + E++++  I   + D K  + I  L++   + ++E I+    D  Y      IP +G V +   V  CQ  I  ++++ L+  +K    ++L   +++     +       +   E  + N   S  ++L + L  +Y+    + ++          F+  +       + N +   ++    +V V + +WK + A   L K +   +A+++  SL E F   H+ F   I    +   +     +  R  +L  AP    L +    +  ++KF   +K ++IG GAQ  VF             V+K + + +   L ++  E+ ++    H NI+ ++     S  + G S+Q+    M+ +L D +   + S++ +++IA+++A+ L YLH +E+IH+D+K+ N+L+   ++  ++D G CK   +I       PI++APE+  +++ K ID+YA+G+LLW + EG G +P+  I    L  V+   +  DN     PE+++ FP++ WQLM  CW+  P+ RP  D+++ +L+ F
Sbjct:  100 QEPALIFVGQTNCGKSSIINELLGCKALPTSDQPSTARIVRVCHAEEPYCRLVDTHGKTLEEIKMMGKEGNRIPRKKIELKPKDRDDPSKVGAIVETGLNIEFLKCGVTIIDSPGRNENKALDNLVKEQLKNPLAFVIYVVDGHDLFTKQDREVLNEMTSSGTDLSIFFVVSKLEPEDRTESSDEDDEPRGHAAPVKARKKRELEVQNRKKTRVYERLVKNGHFPSQL-SMNQNERFHGLSAWRIQQYHALKKRNPEASSEEFTDYTQAFERFQNSLKEFAEESLRARVACVCRTLVRVLSRCLDFFIQKANVLKRGKKQILKTLETLLREEQQVHENIIRDLEDEKRAMEIQELLSDAINGAREDILKGAGDFEYVLTEFTIPSDGHVKEKQAVAYCQDQIQGMVVKKLQGEIK----QKLTMMFRSRDLFLVHLKDGMEQIQGEIARDNDIPSAALALGKSLLSSYE----AQITFPQRNGAALRFIKQLSEWFYNAIRNPIKTIIKTISGEVQVGSKKWKTDVASNALAKVNPSDMAQKIVTSLKELFRDCHEEFTGEIRKVQDLFDRGETIKDMQRETLLGFAPNLALLEMLAYGVMDRFKFGLPAKGELIGTGAQGNVFACDNIKTPEGRPCVVKVVGVASEEVLKDLTLELHNTRALHHPNILPVICTVVESNPNCGLSVQLVSERMRCDLHDGL-VGIPSLRKRLEIALDVAKALQYLHGEELIHRDVKMQNVLLDEKNNAKLTDLGLCKPEGLICNSLVGTPINMAPEMLKQQYDKSIDVYAFGMLLWRVCEGQGNQPQN-INRHFLPLVMLMMNAVDNK---TPERLDVFPEQCWQLMVRCWNQDPEARPSFDSVVRDLETF 956
[Close]
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1S3JVK3 (dual serine/threonine and tyrosine protein kinase OS=Lingula unguis OX=7574 GN=LOC106176299 PE=4 SV=1)

HSP 1 Score: 256.529 bits (654), Expect = 2.585e-68
Identity = 222/867 (25.61%), Postives = 411/867 (47.40%), Query Frame = 2 
Query:  401 PVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELIS------VCPNIEIIYFITHLDGEDLDSETANPIAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQ-SSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIVNDPFIVDQCQRTIMKILI--------QGLENVLKT----FVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLI---SLERILNRNYKLDRLSTVSTDGNQSVV-FEFMNVVLSSVKGF---LSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFK-GIYNNAEIVIKEIK--LNVYTLDNIAKEVFHSHRFSHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERM---PIHVAPEVKMKE--FTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFD----NDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            P +I  GQ   GKS+ IN +L+K ++P +   CT R+ R+++SEN +        R+ E +      S+  + ++L +++R++ NEI+K V  G+KN  L+SG+DIIDSPG    + L  L K  V+ + P+++YV+DG   +   D  DL  L +      V   ++           +   E A P  + Q +M + + +L     +   +   ++C  FHG S   L EA +   +  + T +L  F+ F+      +      K+  +C  L   Q      ++++AE+     ++ ++ I++IK +E++ Y +++  ++D K  +   L   L    +E++  I    +     I E   V     V +C   +  ILI        +GL+N+ +      +E +  QN +N                    + G    L+   SL + L  +YK      +  D ++ V    F   +   +  F   +++ +        + VK   WK   A+++L   D   LA EV ++L   F++ H  F+ NII   N +++ +   ++  + I   AP+   + L  + I    K+   +    IG+G Q EV++    + A   +K +    +   L  +A E+ ++   SHE++M +LG  + + D  + + + Y LM+S++   +  +   +K ++ I +++A  L+Y+H   ++H+D+K  N+L+ S     ++D+G CK +  A  N+ +   P+ +APE+  KE  +   +D+Y++GILLW+L +G G+ P        LN VVW  ++F          +PE+   F D+ WQLM+ CW + P  RP  D II++L+
Sbjct:   66 PCVIFTGQTNCGKSSLINEILQKSVLPANETPCTARLVRLTFSENPYY-------RIGEDEEVAMKGSIPRQVVQLGVDDRRDANEIAKYVTCGIKNGLLKSGLDIIDSPGRNENEELNQLLKNEVERI-PILVYVVDGHNQLTIQDAEDLRTLYNQFVVFYVVSKVDSEDDSDSDSDSESGDEKATPAGVKQERMAVVYSRLVEEGLL-DKHTRMNECQLFHGLSAWKLHEARESAMADSKHTVYLADFENFKSCLIGHIEEILEAKVTIACNNLAKAQKRCIDSLLSKAED-PLTIEETLKDIEKIKLLEQDFYRRVEQKLTD-KTRMEMSLKTILSQCQEELVEDIGQITFERQHNIQEGAYVTGEEAVKKCGDHVKDILITRLIDKYQKGLKNIFQNEESLMLELQRTQNLKNT-------------------REGIKHALVLVCSLTQSLFDSYK------IPLDLSKCVRNLTFWGRLKEGLWNFFRAIAHPIDFIRGRTMITVK---WKQGIARKFLASIDTMNLASEVAEALKSRFDVAHINFQENIIEHKNNVERSLRLSKEQLSSIQQVAPKMASVELRTIGILDVLKYGTPTFLRQIGEGGQGEVWEVTARDKANYALKLVGDPGSEDLLGKLALEIHYTRSISHEHVMPVLGSFVIEKDGKQHLAVLYELMESDVMHMLRNDPGDLKIRLGIGLQVASALNYMHSAGLMHRDIKPENVLLDSEKKAKLADFGLCKPL--AMSNQTICGTPLFLAPEILDKEGSYDPSVDVYSFGILLWFLCDGRGKNP--------LN-VVWL-ALFGLCGFCRLGERPERRPNFSDECWQLMTTCWDSDPKKRPSFDDIISKLK 881
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:103034670])

HSP 1 Score: 109.383 bits (272), Expect = 7.379e-25
Identity = 72/251 (28.69%), Postives = 131/251 (52.19%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            IG+G    V++G Y   ++ +K IK +V T      E     +  H+N++ +LG+   +    +  F  + K NL +Y+     +VIS    +  A+E+ EG+ YL  ++++H+DL   NIL+S ++   +SD+G  K    AF N ++P+   APE +K K+ + + D+++YG+LLW +F   G +P   + L+ + + V      +  ++M  E     P +++ +M +CW   P  RP    +   LQ
Sbjct:  174 IGEGEFGAVYEGEYMGRKVAVKNIKSDV-TAQAFLGETSVMTKLQHKNLVQLLGVILHNGLYIVTEF--MAKGNLVNYLRSRGRSVISTVQLLHYALEVCEGMEYLECKKLVHRDLAARNILLSEDNVAKVSDFGLAKVDSQAFDNTKLPVKWTAPEGLKNKKISTRSDVWSYGVLLWEIFS-YGMQPYPKMSLQEVKEQV------EQGYRM--EAPEACPPEVYTIMRDCWEKEPKMRPSFHKLRELLQ 412
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:103034670])

HSP 1 Score: 108.997 bits (271), Expect = 1.464e-24
Identity = 72/251 (28.69%), Postives = 131/251 (52.19%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            IG+G    V++G Y   ++ +K IK +V T      E     +  H+N++ +LG+   +    +  F  + K NL +Y+     +VIS    +  A+E+ EG+ YL  ++++H+DL   NIL+S ++   +SD+G  K    AF N ++P+   APE +K K+ + + D+++YG+LLW +F   G +P   + L+ + + V      +  ++M  E     P +++ +M +CW   P  RP    +   LQ
Sbjct:  201 IGEGEFGAVYEGEYMGRKVAVKNIKSDV-TAQAFLGETSVMTKLQHKNLVQLLGVILHNGLYIVTEF--MAKGNLVNYLRSRGRSVISTVQLLHYALEVCEGMEYLECKKLVHRDLAARNILLSEDNVAKVSDFGLAKVDSQAFDNTKLPVKWTAPEGLKNKKISTRSDVWSYGVLLWEIFS-YGMQPYPKMSLQEVKEQV------EQGYRM--EAPEACPPEVYTIMRDCWEKEPKMRPSFHKLRELLQ 439
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:103046562])

HSP 1 Score: 107.842 bits (268), Expect = 2.223e-23
Identity = 82/271 (30.26%), Postives = 134/271 (49.45%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKI------AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC-----KSMVIAFYNERMPIHVAPEV-KMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQ--VVWENSIFDNDFQMK-PEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE +S+   +G GAQ  VF G ++  E+ +K+++      D    E+ H  +  H NI+T  G+        I + Y   +  L     Y V+    KI        AM IA G++YLH  ++IH+DLK PN+LI+ +D V ISD+G       KS  ++F        +APEV + +  ++K+DI+++G++LW +         G I  K ++   ++W   + +N  Q+  PE     PD    L+ +CW+  P +RP    I+  L I
Sbjct:  148 FEEISELQWVGSGAQGAVFLGKFHGEEVAVKKVR------DIKETEIKHLRKLKHPNIITFKGVCTQAPCYCIIMEY-CAQGQL-----YEVLRAGRKITPSLLVDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITHDDLVKISDFGTSKELREKSTKMSFAG--TVAWMAPEVIRNEPVSEKVDIWSFGVVLWEML-------TGEIPYKDVDSSAIIW--GVGNNSLQLPLPESC---PDGFKILLKQCWNCKPRNRPSFRQILLHLDI 392
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:103046562])

HSP 1 Score: 107.842 bits (268), Expect = 2.384e-23
Identity = 82/271 (30.26%), Postives = 134/271 (49.45%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKI------AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC-----KSMVIAFYNERMPIHVAPEV-KMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQ--VVWENSIFDNDFQMK-PEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE +S+   +G GAQ  VF G ++  E+ +K+++      D    E+ H  +  H NI+T  G+        I + Y   +  L     Y V+    KI        AM IA G++YLH  ++IH+DLK PN+LI+ +D V ISD+G       KS  ++F        +APEV + +  ++K+DI+++G++LW +         G I  K ++   ++W   + +N  Q+  PE     PD    L+ +CW+  P +RP    I+  L I
Sbjct:  148 FEEISELQWVGSGAQGAVFLGKFHGEEVAVKKVR------DIKETEIKHLRKLKHPNIITFKGVCTQAPCYCIIMEY-CAQGQL-----YEVLRAGRKITPSLLVDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITHDDLVKISDFGTSKELREKSTKMSFAG--TVAWMAPEVIRNEPVSEKVDIWSFGVVLWEML-------TGEIPYKDVDSSAIIW--GVGNNSLQLPLPESC---PDGFKILLKQCWNCKPRNRPSFRQILLHLDI 392
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-45c16.2 (mitogen-activated protein kinase kinase kinase 13 [Source:NCBI gene;Acc:103032151])

HSP 1 Score: 102.064 bits (253), Expect = 1.410e-21
Identity = 76/265 (28.68%), Postives = 130/265 (49.06%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC-----KSMVIAFYNERMPIHVAPEV-KMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQ--VVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE +S+   +G GAQ  VF G +++ E+ IK+++    T      ++ H  +  H NI+   G+        I + Y   +  L + +     IS +  +  A  IA G++YLH  ++IH+DLK PN+L++ ND+V ISD+G       KS  ++F        +APEV + +  ++K+DI+++G++LW L  G        I  K ++   ++W   +  N   +     +  PD    LM + W   P +RP    I+  L I
Sbjct:  194 FEEISELQWLGSGAQGAVFLGKFHSEEVAIKKVREQKET------DIKHLRKLKHPNIIGFKGVCTQAPCYCIIMEY-CAQGQLYEVLRAGRKISPRLLVDWASGIASGMNYLHLHKIIHRDLKSPNVLVTHNDAVKISDFGTSKELSDKSTKMSFAGTVA--WMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE-------IPYKDVDSSAIIW--GVGSNSLHLP--VPSTCPDGFKILMKQTWQGKPRNRPSFRQILLHLDI 438
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008193.1 (pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-1 gene:ENSPMAG00000007385.1 transcript:ENSPMAT00000008193.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.605 bits (257), Expect = 7.709e-24
Identity = 76/266 (28.57%), Postives = 130/266 (48.87%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-----VAPEVKMKE-FTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQ--VVWENSIFDNDFQMK-PEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE +S+   +G GAQ  VF G +    + +K+++    T      ++ H H+  H NI+T  G+        I + Y   +  L + +     IS +  +     IA G+ YLH  ++IH+DLK PN+LI+ +D V ISD+G  K M     + RM        +APEV   E  ++K+DI+++G++LW L  G        I  + ++   ++W   +  N   +  P      P+    L+++CW++ P +RP    I+  L+I
Sbjct:   11 FEEISELQWLGSGAQGAVFLGKFRGEHVAVKKVREQKET------DIKHLHKLRHPNIITFKGVCTHAPCYCIIMEY-CAQGQLYEVLRAGRRISPELLVGWTRGIARGMSYLHLHKIIHRDLKSPNVLITHDDEVKISDFGTSKEM--REKSTRMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE-------IPYRDVDSSAIIW--GVGSNSLHLPIPASC---PEGFKILLTQCWNSKPRNRPSFRQILLHLEI 255
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7])

HSP 1 Score: 88.9669 bits (219), Expect = 1.135e-18
Identity = 70/264 (26.52%), Postives = 129/264 (48.86%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNAEIV-IKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMK-SNLRDYINYNV---ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNE-------RMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAIC-LKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQIFE 2890
            +G G   EV++G++NN+ +V +K +K      +    E     +  H N++ +  +   ++   I I   LM+  +L DY+   +   +     + +A +IA G+ YL  Q  IH+DL   NIL+       ++D+G  + + + + +E       ++PI   APE V    F+ K D++++GILL+ L    GR P   +  ++ L Q+       D  ++M P+  N  P   + +M ECW+   ++RP  +T+   L  F+
Sbjct:  195 LGAGMFGEVWQGLWNNSTLVAVKTLKPGAMKKEEFIGEAQIMKQLRHANLIQLYAVCSQEE--PIYIITELMRHGSLLDYLRGPLGKQLKAPELVDMARQIAAGMAYLESQNYIHRDLAARNILVGEGKVCKVADFGLARIIKVRYEDEYEGKAGAKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELIT-YGRMPYPEMGNMEVLKQL-------DRGYRM-PQPDN-CPPLFYSIMLECWNKKEEERPTFETLQWRLDYFD 446
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009736.1 (pep scaffold:Pmarinus_7.0:GL479388:5844:12989:-1 gene:ENSPMAG00000008798.1 transcript:ENSPMAT00000009736.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 2.386e-17
Identity = 51/234 (21.79%), Postives = 112/234 (47.86%), Query Frame = 2 
Query: 2222 NVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNV--ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFY-------NERMPIH-VAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQIFE 2890
            +V  ++   +E      F HEN++++LGI     G  + +   +   +L  ++       ++K+ I   +++A G+ YL  ++ +H+DL   N ++  + +V ++D+G  + +    Y         ++PI  +A E ++ + FT K D++++G+LLW L      + +GA     ++       +       +PE     PD++++ M +CW     DRP    ++  L++ +
Sbjct:    3 DVEEVEQFLREGLLMKNFQHENVLSLLGICMPLHGTPLVVLPYMKHGDLGHFLRQETHNPTVKDLIGFGLQVARGMEYLASKKFVHRDLAARNCMLDESYTVKVADFGLARDIYNKEYYSIRNHQRAKLPIKWIALESLQTQRFTTKSDVWSFGVLLWEL------QTRGAPPYPDVDPFDMARFLRQGRRLPQPEYC---PDELFERMLDCWGPTAGDRPGFPELVRRLELLQ 227
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57])

HSP 1 Score: 83.9593 bits (206), Expect = 4.198e-17
Identity = 63/247 (25.51%), Postives = 116/247 (46.96%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGIYNNA-EIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYI---NYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSM----VIAFYNERMPIH-VAPEVKM-KEFTKKIDIYAYGILLWYLFEGSGREP-KGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            +G+G   EV+ G +N   ++ IK +K    + +   +E     +  H+ ++ +  +   +    +  F  + K +L D++   +   + +   + +A +IA G+ Y+     IH+DL+  NIL+  N    I+D+G  + +      A    + PI   APE  M   FT K D++++GILL  L    GR P  G +  + L QV       +  ++M        P+ + +LM +CW   P++RP
Sbjct:  213 LGQGCFGEVWAGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEF--MSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAAMFGRFTIKSDVWSFGILLTELVT-KGRVPYPGMVNREVLEQV-------ERGYRMPCPP--SCPESLHELMMQCWKKDPEERP 447
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004129.1 (pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene:ENSPMAG00000003774.1 transcript:ENSPMAT00000004129.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 80.8777 bits (198), Expect = 6.159e-17
Identity = 62/247 (25.10%), Postives = 126/247 (51.01%), Query Frame = 2 
Query: 2138 DMIGKGAQSEVFKGIYNNA-EIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMK-SNLRDYINY--NVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNER---MPIH-VAPEVKMK-EFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            +++G+G   EV++G +N+  ++ IK ++ N  + D   KEV     F HEN++ I  + K  +     I   L+   N+  Y+    + +S   ++ +A  IA G+ YL ++  IH DL   NIL+  ++   ++D+G    +   +Y+     +P   +APEV ++ +FT+K D++++G+LL+ LF   G+ P   +  + +  ++            + ++ +  P+ ++ +M  CW+     RP
Sbjct:   27 NLLGRGNFGEVYEGRWNDTTDVAIKIVRTNS-SFDTFMKEVKTMISFKHENVLQIYAVCK--EKWPYWIVTELVPYGNMLHYLGRFGHELSEVERLYMAFGIASGMAYLSKKRCIHCDLAGRNILMGQHNICKVADFGLSHKLKEEYYDATGHVVPFQWMAPEVLIQLKFTRKSDVWSFGVLLYELFT-DGKRPYADMDKQQVQDLI--------KCGGRLKRPDACPNVVYHIMQRCWNFEHRKRP 261
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: MKK1 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757])

HSP 1 Score: 67.0106 bits (162), Expect = 7.265e-12
Identity = 52/193 (26.94%), Postives = 89/193 (46.11%), Query Frame = 2 
Query: 2141 MIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLD-----NIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKI------KIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMV--IAFYNERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLFEG 2677
            ++G+GA   V K    N   +     +N    D      I +E+  +  F  E I+   G+   D+  SI I    M     D I  N++    +I      KIA  +  GL YLHE++VIH+D+K  NIL++ N  V + D+G     V  +A        ++APE ++ + ++   D+++ G+ +  +  G
Sbjct:  226 ILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANG 418
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952])

HSP 1 Score: 64.3142 bits (155), Expect = 1.965e-11
Identity = 54/242 (22.31%), Postives = 118/242 (48.76%), Query Frame = 2 
Query: 2144 IGKGAQSEVFKGI--YNNAEIVIKEIKLNV--YTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMK------NKIK-IAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVI---AFYNERMPI-HVAPEVKM--KEFTKKIDIYAYGILLW------YLFEGSGREPKGAI---CLKTLNQVVWENSI----FDNDFQMKPEK 2779
            +G G  + V+KG+       + +KE+KL+    T     +E+       HENI+ +  +  +++   + + +  M ++L+ Y++   +         N +K    ++ +GL + HE +++H+DLK  N+LI+    + + D+G  ++  I    F +E + + + AP+V M  + ++  IDI++ G +L        LF G+  E +  +    + T N+ +W +      ++ + Q +P +
Sbjct:   13 LGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTEN--KLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPR 252
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: PKC1 (Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201])

HSP 1 Score: 65.855 bits (159), Expect = 2.724e-11
Identity = 36/106 (33.96%), Postives = 61/106 (57.55%), Query Frame = 2 
Query: 2375 YINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNER------MPIHVAPEV-KMKEFTKKIDIYAYGILLWYLF 2671
            ++    +S++     A E+   L Y H+  VI++DLKL NIL++    + I+DYG CK  +  +Y  R       P  +APE+ K +E+TK +D +A+G+LL+ + 
Sbjct:  915 HVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEM--WYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQML 1018
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242])

HSP 1 Score: 65.4698 bits (158), Expect = 2.800e-11
Identity = 32/92 (34.78%), Postives = 54/92 (58.70%), Query Frame = 2 
Query: 2417 IAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNER----MPIHVAPE-VKMKEFTKKIDIYAYGILLWYLFEG 2677
            I  E  +GL +LH++ +IH+D+K  N+L+ +   V I+D+GFC  +             P  +APE VK +E+ +KID+++ GI+   + EG
Sbjct:  673 IVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEG 764
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 65.0846 bits (157), Expect = 5.348e-11
Identity = 67/263 (25.48%), Postives = 129/263 (49.05%), Query Frame = 2 
Query: 1979 RNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIV-------NIEGKYK-FEYVSKTDMIGKGAQSEVFK--GIYNNAEIVIKEIKLNVY---------TLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFY---PLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVC-ISDYGFCKSMVIAFYNERMPIH-----VAPE-VKMKE-FTKKIDIYAYGILLWYLFEG 2677
            R I  E++  +K  V L++  TK+     R   +  N +       N +G+YK F ++ K +MIGKG+   V+    +     + +K++++  Y         T++ +  EV       H NI+  LG    ++  S+ + Y     + S +R Y  ++   +K+   +  ++ +GL YLH + ++H+D+K  N+L+   D +C ISD+G  +     + N  M +      +APE V  K+ ++ K+DI++ G ++  +F G
Sbjct: 1121 RTIAHEASLARKNSVKLKRQNTKMWGT--RMVEVTENHMVSINKAKNSKGEYKEFAWM-KGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKH---LTTQVLKGLAYLHSKGILHRDMKADNLLL-DQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAG 1376
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49815 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG13])

HSP 1 Score: 114.39 bits (285), Expect = 1.078e-28
Identity = 55/166 (33.13%), Postives = 99/166 (59.64%), Query Frame = 2 
Query: 2390 VISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKS-MVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVW-ENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            + S++ +++I +++A  L YLH  ++IH+D+KL N+L+       ++D+G CK+  V+       P  +APE+  + + K +D+YA+GIL+W + EG G +P+  I L  +  ++   N++ D     KPE++++F    W LM  CW+  PD RP+   I ++LQ
Sbjct:   50 LTSLRKRLEILLDVARALKYLHSLDLIHRDVKLQNVLVDEKSQGSLTDFGLCKAEGVMENSLVGTPTSMAPEMVKQNYNKSVDVYAFGILMWRVCEGQGNQPRN-IALHPIPIIMLVRNALEDR----KPERLDRFMGPCWNLMERCWATVPDQRPNFQEIESDLQ 210
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO44458 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVW1])

HSP 1 Score: 120.553 bits (301), Expect = 7.858e-28
Identity = 96/407 (23.59%), Postives = 192/407 (47.17%), Query Frame = 2 
Query: 1667 TSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI-ISESNFIKKEVVTLEKIRTKIL-NNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKG--IYNNAEIVIKEI-KLNVYTLDNIAKEVFHSHRFS-HENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKS-MVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQ-MKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            TS  ++L+ +++  Y+++ ++  ++     +++E M   + ++ G     +            +  WK   A++ L       LA+ +C          H++F   + + E+N   +   T E+ R K+  ++AP+   L L   ++     +     +  +G+G    V+            IK +   +    +++A E F++     H+ +++I+G  I  S  G S      +M    RD Y      +S + ++ +A+++ EG+ +LH Q ++H+D+KL N+L+ S +   I+D GFCK   +++      PIH+APE+    +   +D+YA GILLWY+  G+ R P          Q   ++ +++   + ++PE++  F ++ W LM  CWS  P  RP
Sbjct:  493 TSATVALKHVIDAAYQVE-VTYRASSSLARLLWEKMKQAIQTLPGKTPPKV------------DSAWKRKVAQDMLTSLSETRLAKHICLQFRTRLIKSHESFTSCMRMLEANHTGRLEKTEEQ-RMKVRKSHAPKIARLALESWSLRDVVLYGMPQLSREVGRGQYGVVYACDRWAGRHPCAIKSVVPPDDKHWNDLALEFFYTRSLPLHDRVVSIIGSVIDYSYGGGSSPAVLLVMDRLQRDLYQGIKAGLSFRARMHVAVDVVEGIRFLHSQGLVHRDIKLKNVLLDSKNRGKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGHYDNSVDVYALGILLWYICAGTVRLPLA------FEQCASKDHLWNAVRRGVRPERLANFDEECWMLMEACWSGDPSARP 879

HSP 2 Score: 53.5286 bits (127), Expect = 4.571e-7
Identity = 43/178 (24.16%), Postives = 86/178 (48.31%), Query Frame = 2 
Query:  380 ENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTN---RVTRISYSENNFIELIDSDG---RVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIY 895
            +++  + P IIV+GQ    K   IN LL + ++P   D+  +   R+ RI Y   + + L+  D          +    + V    ++LN  E+ +P   S V +I + +  L++G  ++ SP     D          ++VLP+++Y I+ +  +   D A+LL++ ++ P++ I +
Sbjct:   57 DSVCEKPPTIIVVGQTCFAKVCVINELLGEPVLPSVEDLEGDRSWRMIRIKYGNISNVSLVLPDSFELAAALNAYEGCWQCVPRGDLELNDEEKADPAMASAVAEISLNHALLKAGAQLVCSPSNPEGDAENIF-SACCEDVLPILVYSIE-QDFLSDKDEAELLQIKALAPDLPIFF 232
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO37575 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFG8])

HSP 1 Score: 114.005 bits (284), Expect = 4.051e-27
Identity = 74/265 (27.92%), Postives = 134/265 (50.57%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMP--------IHVAPEVKMKE-FTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE + +   +G GAQ  VF G+Y++ ++ +K+++    T      ++ H    +H NI+   G+        + + Y           +   I+ +  +    +IA+G+HYLH  ++IH+DLK PNIL+SSND + ISD+G CK      +NE+            +APEV   E  ++K+D++++G+LLW L   +G  P   +     + ++W   +  N+ Q+     +  P+ I  LM  CW++ P +RP    ++  ++I
Sbjct:   32 FEEIHELQWLGSGAQGAVFLGVYSDEQVAVKKVRHEKDT------DIKHLRNLNHPNIIRFKGVCNQAPVYCVVMEYCPYGQLFEVLRDGREITPELLVGWTTQIADGMHYLHGNKIIHRDLKSPNILVSSNDILKISDFGTCKE-----FNEKSAKMTFAGTVAWMAPEVIRNEPCSEKVDVWSFGVLLWELL--TGELPYKGV---DSSAIIW--GVGSNNLQLPVP--STCPEGIQLLMKLCWNSKPKNRPSFRQVLMHIEI 276
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49816 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG14])

HSP 1 Score: 114.39 bits (285), Expect = 4.066e-26
Identity = 55/141 (39.01%), Postives = 89/141 (63.12%), Query Frame = 2 
Query:  395 ENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDG 817
            + P +IV GQ   GKS+ IN  L   +VP     CT R+ R++YSE  ++ L+  DG  +E++  +S+K +  +FI+LN+++R +   ++  V+ G+   FL++GID+IDSPG    D L  L +  +K++LP VIYV+DG
Sbjct:  100 QTPALIVTGQTNCGKSSIINEFLGARVVPTKAQPCTARIVRMTYSETPYVRLVKRDGTELERRELKSNK-IPREFIELNIDDRDDEKRVNATVEAGLCVDFLKAGIDVIDSPGTSENDVLDELVRNQMKSILPFVIYVVDG 239
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49580 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGQ2])

HSP 1 Score: 102.834 bits (255), Expect = 2.597e-22
Identity = 78/279 (27.96%), Postives = 136/279 (48.75%), Query Frame = 2 
Query:  359 QEIELIRENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISK-VVKIGVKNKFLESG-IDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDLDSETANPIAIS---------QRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETIL 1162
            QE +   E +S +   I+V+GQ  +GKS+ IN LL    +P +   CT+R+ RI YS+NN++E+   +G  ++ K     K +    I L+ +++++  E  + VVK+G+ N  L  G ++++D+PGM   + L  + +  +  +L VVIYVIDG + ++  D   L  L     +I I +    +D     +E       S         + KM  +++ L  +  I S  +    C  FHG S   + +A  K+   + T   + F+  +  F T L
Sbjct:   80 QETQKFEEFVS-KKAAILVVGQTNSGKSSLINELLGGTYLPTAEIPCTSRIVRICYSDNNYVEVQGPNGECVQGKQSFGKKRIPRDEIALDDDKKRSDAEWVRCVVKVGLNNSLLRGGHLELVDAPGMSENEVLDQIVQECIHGILQVVIYVIDGNSSLRTQDREFLFSLKERIDSIPIFFVCNKVDTNAKAAEFDRDSDDSDDDSSLDNVETKMRQAYKALVGYGLIDSDIQ-LEDCAAFHGISTHEVRKARHKKIHNQFT---DAFEVMKSSFLTFL 353
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: dstyk (dual serine/threonine and tyrosine protein kinase [Source:NCBI gene;Acc:100144388])

HSP 1 Score: 123.25 bits (308), Expect = 3.176e-28
Identity = 97/348 (27.87%), Postives = 165/348 (47.41%), Query Frame = 2 
Query: 1856 NPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNI--ISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNI-----VNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNA--EIVIKEIKLNVYTLDNIAKEVFHSHRF--SHENIMTILG--ISKSDDGKSIQIFYPLMKSNLRD-YINYNV-ISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKS-MVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
             PEWK   A++ ++      LA  +C          H+ F  ++  + E +  + E      +R +  ++APR   L L       V + GK +          G     E + G Y  A   +V  + K      +++A E FH  R    HE ++ + G  I  S  G S      +M+   RD Y      +S++ +++IA+++ EG+ +LH Q ++H+D+KL N+L+   +   I+D GFCK   +++      PIH+APE+   ++   +D+YA+GIL WYL  GS + P+      + +Q +W N         +PE++  F ++ WQLM  CW+  P  RP
Sbjct:  543 TPEWKRKVAQDAIESLSAAKLARSICSQFRTRLNSSHEAFAASLRQLEEGHTGRLERTEDLWLRVRK-DHAPRLARLSLESRSLRDVLLHGKPRLGRELGRGQYGVVYLCESWGGHYPCALKSVVPPDDK----HWNDLALE-FHYTRSLPKHERLVDLHGSVIDHSYGGGSSIAVLLIMERLHRDLYTGLKAGLSLRERLQIALDVVEGIRFLHGQGLLHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYLCTGSVKLPEAFEKCSSKDQ-LWNNV----KKGARPERLPSFDEECWQLMEACWNGDPSLRP 879
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:101164299])

HSP 1 Score: 107.457 bits (267), Expect = 5.004e-24
Identity = 70/234 (29.91%), Postives = 122/234 (52.14%), Query Frame = 2 
Query: 2168 VFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM-KSNLRDYINYNVISMKNKIKI---AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPEVKMKE-FTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            V++G Y    + +K IK +V T     +E     +  H+N++ +LG+  +   K + I   LM K NL +++     S+   I++   ++++ EG+ YL  ++++H+DL   NIL+S +++  ISD+G  K +       ++PI   APE   KE F+ K D+++YG+LLW +F   GR+P   + LK +   V      +  ++M  E     P  ++ LM  CW   P  RP
Sbjct:  205 VYEGEYVGQRVAVKTIKCDV-TAQAFLQETAVMTKLQHKNLVRLLGVILN---KGLHIVTELMIKGNLVNFLRTRGRSVVTSIQLFRYSLDVCEGMEYLESKKLVHRDLAARNILVSDDNAAKISDFGLTKVVSKEADKAKLPIKWTAPEALTKEKFSTKSDVWSYGVLLWEIFS-YGRQPYPKMSLKDVQAKV------EAGYRM--EAPEDCPANVYSLMKLCWEQEPRRRP 425
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: matk (megakaryocyte-associated tyrosine kinase [Source:NCBI gene;Acc:101164299])

HSP 1 Score: 107.457 bits (267), Expect = 5.004e-24
Identity = 70/234 (29.91%), Postives = 122/234 (52.14%), Query Frame = 2 
Query: 2168 VFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLM-KSNLRDYINYNVISMKNKIKI---AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIH-VAPEVKMKE-FTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRP 2851
            V++G Y    + +K IK +V T     +E     +  H+N++ +LG+  +   K + I   LM K NL +++     S+   I++   ++++ EG+ YL  ++++H+DL   NIL+S +++  ISD+G  K +       ++PI   APE   KE F+ K D+++YG+LLW +F   GR+P   + LK +   V      +  ++M  E     P  ++ LM  CW   P  RP
Sbjct:  205 VYEGEYVGQRVAVKTIKCDV-TAQAFLQETAVMTKLQHKNLVRLLGVILN---KGLHIVTELMIKGNLVNFLRTRGRSVVTSIQLFRYSLDVCEGMEYLESKKLVHRDLAARNILVSDDNAAKISDFGLTKVVSKEADKAKLPIKWTAPEALTKEKFSTKSDVWSYGVLLWEIFS-YGRQPYPKMSLKDVQAKV------EAGYRM--EAPEDCPANVYSLMKLCWEQEPRRRP 425
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: MAP3K12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:101160549])

HSP 1 Score: 105.916 bits (263), Expect = 9.157e-23
Identity = 80/270 (29.63%), Postives = 133/270 (49.26%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKI------AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC-----KSMVIAFYNERMPIHVAPEV-KMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQ--VVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE +S    +G GAQ  VF G  +  E+ +K+++ N+   D     + H  +  H NI+T  GI        I + Y   +  L     Y V+    KI        AM IA G++YLH  ++IH+DLK PN+LI+ +D+V ISD+G       KS  ++F        +APEV + +  ++K+DI+++G++LW +         G +  K ++   ++W   + +N  Q+     +  PD    L+ +CW+  P +RP    I+  L I
Sbjct:  171 FEEISDLQWVGSGAQGAVFLGKLHGQEVAVKKVR-NIKETD-----IKHLRKLKHPNIITFKGICTQAPCYCIIMEY-CAQGQL-----YEVLRAGRKITPSLLMDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDAVKISDFGTSKELSDKSTKMSFAG--TVAWMAPEVIRNEPVSEKVDIWSFGVVLWEML-------TGEVPYKDVDSSAIIW--GVGNNSLQLP--VPDSCPDSFKLLLRQCWNCKPRNRPSFRQILLHLDI 415
[Close]
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: MAP3K12 (mitogen-activated protein kinase kinase kinase 12 [Source:NCBI gene;Acc:101160549])

HSP 1 Score: 105.531 bits (262), Expect = 9.920e-23
Identity = 80/270 (29.63%), Postives = 133/270 (49.26%), Query Frame = 2 
Query: 2117 FEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKI------AMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFC-----KSMVIAFYNERMPIHVAPEV-KMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQ--VVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQI 2884
            FE +S    +G GAQ  VF G  +  E+ +K+++ N+   D     + H  +  H NI+T  GI        I + Y   +  L     Y V+    KI        AM IA G++YLH  ++IH+DLK PN+LI+ +D+V ISD+G       KS  ++F        +APEV + +  ++K+DI+++G++LW +         G +  K ++   ++W   + +N  Q+     +  PD    L+ +CW+  P +RP    I+  L I
Sbjct:  153 FEEISDLQWVGSGAQGAVFLGKLHGQEVAVKKVR-NIKETD-----IKHLRKLKHPNIITFKGICTQAPCYCIIMEY-CAQGQL-----YEVLRAGRKITPSLLMDWAMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDAVKISDFGTSKELSDKSTKMSFAG--TVAWMAPEVIRNEPVSEKVDIWSFGVVLWEML-------TGEVPYKDVDSSAIIW--GVGNNSLQLP--VPDSCPDSFKLLLRQCWNCKPRNRPSFRQILLHLDI 397
[Close]
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056722.1 (SMESG000056722.1)

HSP 1 Score: 1815.05 bits (4700), Expect = 0.000e+0
Identity = 927/929 (99.78%), Postives = 929/929 (100.00%), Query Frame = 2 
Query:  104 MLRNSFISRFSKRRLSVNKDYDTELSKCIYKYRQSREELISSINETIKLFDEFLTEPIPEIIETFDRKSLIDLKTELGERSGPKMQEIELIRENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDLDSETANPIAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQIFE 2890
            MLRNSFISRFSKRRLSVNKDYDTELSKCIYKYRQSREELISSINETIKLFDEFLTEPIPEIIETFDRKSLIDLKTELGERSGPKMQEIELIRENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISK+VKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDLDSETANPIAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSKTKKNIEQIKQIKKIEKEMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVKDKIFKSIKDIKDSYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKG+YNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQIFE
Sbjct:    1 MLRNSFISRFSKRRLSVNKDYDTELSKCIYKYRQSREELISSINETIKLFDEFLTEPIPEIIETFDRKSLIDLKTELGERSGPKMQEIELIRENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKIVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDLDSETANPIAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSKTKKNIEQIKQIKKIEKEMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVKDKIFKSIKDIKDSYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGMYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQIFE 929
[Close]
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056697.1 (SMESG000056697.1)

HSP 1 Score: 765.763 bits (1976), Expect = 0.000e+0
Identity = 393/923 (42.58%), Postives = 622/923 (67.39%), Query Frame = 2 
Query:  176 LSKCIYKYRQSREELI---SSINETIKLFDEFLTEPIPEIIETFDRKSLIDLKTELGERSGPKMQEIEL---------------IRENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDL-DSETANPIAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSD----DGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYN-ERMPIHVAPEVKMKE-FTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTII 2869
            L++ I++YR++RE L+   SS  E      E L     E++E  +  ++  + ++LG  + P  +EIE+               + + + + NP I ++GQ+K GKSTF+N+LLRK++V Q+++ CT R+TR++YS  N++E++D +G+V+E+K   +  ++  K+++LN  +R   +EI+K+V+ G+K++FLE GIDIIDSPG+     LT L K M+K++LP++IYVIDGR  VKQTD ADLLEL +  P ++IIYFI+ LD +D  ++E ++PI +++ KMEL+F+KLQY+NFIP+S+K +S+CPYFHGASL C ++  + + ++EI +H + F KF+   ++ L I F+NKIFE+C+++++FQ+ + TKII +A      TK+N+  I  I+KIE+E++ KIK  IS SK DLI RLI RL+ +S+ IINPI D  YPNSI +PENG+V D  +++QCQ  IM  L QGLENV+K FVE EL+Q Y++A++ ++   +KD    +E    GKT Y +SLERIL  NYK + L+ +S     +V+ + M  +L+S+K F S     +  +  V+VK+ EWK  QAKE LK+CDH  LAEEVCKSL +DFE KH  F   + +E+ F+ K++   E+IRT++   AP F  L +  ++++G+Y  + +   + IG+GAQ EV++   N  E+  K + L +  L++IA+EV++S+ F H  ++ ++ +S +D    D K I IF PLMK+++  Y+  N +S+K ++KIA+++AE L YLH Q+++H+DLKL NIL+  N++V ++DYGFCKSM ++ ++    P+H+APE+  K  +  K+DIY+YG+LLWYL EG+GR P+ A     + QV+W ++    +  M+PE++++  D++W+LM  CW N P  RPD ++++
Sbjct:   13 LNQAIHEYRENRERLLRIQSSTKEAFSQITEILKPTTAELLECVNIDNIAHIASDLGVINKP-TEEIEISAEEFLNKTIYEKQDVNQKVDIGNPAIAIVGQVKAGKSTFVNVLLRKNVVCQAYERCTARLTRLTYSSQNYVEILDENGKVLERKKL-NKPTIPKKYLQLNDEDRTKRSEINKIVRAGIKSQFLEYGIDIIDSPGLSENATLTNLSKNMIKSILPIMIYVIDGRTSVKQTDIADLLELKNAVPKLQIIYFISKLDTDDTTETEFSDPIKLAESKMELAFKKLQYNNFIPTSFKHWSECPYFHGASLYCYMDYYKNKRTEEILFHFDLFGKFEVALQSFLMINFKNKIFEACDSMLNFQMDVLTKIITRARVLSDFTKENLNHIFTIRKIEEELFEKIKGVISSSKNDLIKRLIERLEDESEAIINPIGDLEYPNSISVPENGMVIDKRLIEQCQGVIMSSLCQGLENVIKQFVESELYQKYRDAIEVQVTSRMKDEIGVHEAKCLGKTPYRMSLERILASNYKFNSLTALSNTEGHNVIMKLMQEILNSIKLFFSKLFGTDQIKESVDVKSHEWKTQQAKECLKRCDHSTLAEEVCKSLIDDFENKHNAFLLALENENRFVHKKISVSEEIRTQMAEKAPDFAGLLMLTLDVKGRYMLQGIVVNEKIGQGAQGEVYRCSCNGQEMAKKTVNLPMNQLNDIAEEVYYSYLFQHPRLLPLIAVSITDSTELDSKQISIFAPLMKTDVSKYLKRNKVSIKERLKIALQVAEALQYLHRQQIMHRDLKLANILLDDNNNVFLADYGFCKSMALSNHSFVGTPVHIAPEIVRKAIYDFKVDIYSYGMLLWYLAEGTGRHPRFARVQSNIAQVLWAST----EHNMRPERLDEISDELWELMQACWDNEPSVRPDIESVL 929
[Close]
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056719.1 (SMESG000056719.1)

HSP 1 Score: 607.446 bits (1565), Expect = 0.000e+0
Identity = 334/829 (40.29%), Postives = 543/829 (65.50%), Query Frame = 2 
Query:  176 LSKCIYKYRQSREELISSINETIKLFD---EFLTEPIPEIIETFDRKSLIDLKTELGERSGPKMQEIE------LIRENISLENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDL-DSETANPIAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVST-DGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSD----DGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYN-ERMPIHVAPEVKMK 2614
            L++ I  YRQ+RE L+   + T K FD   E L      +++  D  +L ++  +LG      +   E      +  + + + NP I V+GQ+K+GKSTF+N LLRK++VPQ+F+ CT R+TR++YS  NF+E+I ++G ++++K   +  ++  +F++L  N R +  EI+K +K G+ + FL+ GIDIIDSPG+   + L  L K M+K++LPV+IYVIDGR  VKQTD +DLLEL +  PN++IIYF++ LD +DL ++E A+PI +++ KM+++F+KLQ++NFIP ++  +S+C YFHG SL   ++ +Q   + E  +H   F KF+ +    L   FRNKI E C  L+DFQ+ + TKIIN+A+      + N ++I +IK+IE+++Y KIK A+ DSK  L + LI RLK++S  I+ PI + IYPN + IP +GIV++   + QCQ  I+  + QGLENV+K FVEEELFQ Y  A++ +I   +K+        K+GKT+Y + L+R +   YK +  + +S  DGN +++ +FMNV+ SS+KGFL  GL +E ++  V+VK+P+WK+ QAK+ L++CD  +LA+EVCK+L E+F  KH  F   +  E+ +++K++   ++IR K+   AP F  L +  ++++GKY  + V + + IG G+Q  + + I +  E+  K+  +N+ +++ IA+E+++S+ F H +++  L ++  D    D K + I+ PLMK++L +Y+ +N   + ++I IA++IAE L YLH   ++H+DLKL NIL++ ++SV ++DYGFCKS  +  Y+    P+H+APE+ MK
Sbjct:   15 LTRVIKDYRQNRERLVKIQSSTKKTFDQITEILKSDTGSLLDCVDSNNLNNIAADLGNFEDSDILADEQFYLKSVFEKQVEIGNPAIAVVGQVKSGKSTFVNTLLRKNVVPQAFERCTARITRVTYSMKNFVEIISNEGVILKRKSLNT-TTIPKRFLQLKENVRIDEEEINKQIKAGIHSNFLKCGIDIIDSPGLSENETLNNLSKNMIKSILPVMIYVIDGRTSVKQTDISDLLELKNAVPNLQIIYFVSKLDTDDLSETENADPIKLAELKMDIAFKKLQFNNFIPLTFSHWSECNYFHGCSLYAFMDYTQNSRTPETLFHYNLFCKFEENLHHYLLQNFRNKIEEVCNFLIDFQMEVMTKIINRAQMLSDFNRINFDEINRIKRIEEKLYKKIKSAVKDSKIHLKSCLIKRLKNESDVIVKPISEIIYPNHLNIPLDGIVSEKQQIKQCQSIIISNVCQGLENVIKRFVEEELFQKYLEAIQAQIPFRMKNKISV---TKSGKTNYGLCLDRRMAEIYKFNISNNLSNLDGNNTIM-KFMNVIRSSIKGFLMTGLKIEFSQKSVDVKDPKWKMKQAKKCLERCDFKILADEVCKNLLEEFYKKHNEFLAVMDLENFYVQKKIELSDEIRQKLAEKAPIFAELLMLSLDVKGKYFLQNVEEKEEIGSGSQGTIHRCICDGKELAKKKYIVNIDSIEEIAEEIYYSYSFEHPHLLPFLAVAIIDTEEIDSKEVAIYSPLMKTDLYNYLCHNKTKLSHRISIAIQIAEALQYLHSHNIMHRDLKLANILLNEDNSVFLADYGFCKSTALTHYSFVGTPLHIAPEIIMK 838
[Close]
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056716.1 (SMESG000056716.1)

HSP 1 Score: 561.222 bits (1445), Expect = 0.000e+0
Identity = 310/839 (36.95%), Postives = 518/839 (61.74%), Query Frame = 2 
Query:  395 ENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDLDSETANP-IAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIV---NDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSD----DGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYN-ERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            ENP I ++G +K GKST +N+LLRK++V Q+   CT R+TRI+YSE N++EL++   ++IE+K  ++ K +    ++LN  +R NP+E++K++++G+K+KFL+SGID+IDSPG+     L  L   ++  VLPV+IYVIDG+  VKQTD +++L L    PN+ IIYFIT LD +D+     N  I  ++ K++ +FRKLQ  N IP ++  YS+C  FHGASL   ++   K  SQE  +H EQF KF+ D   ILS  F  +I  + ++L+DFQ+ + TKII++A+ F   T +N+++I  ++K+E+ +++ +K  I++SK  LI+RL+ RL ++S  II+ I D  +P SI IPEN      N  F    CQ+ I+ ++ + L+N++  FV++EL +N++N  +  +   I +    Y    + K+ Y + LER L + YK D L     + + S+     N++    +  LSN  F        ++ +  W++ Q K  L  CD  LLA+ +C ++  D  +KH  F  N+  E   I+KE+   E IR KI N    F  L +  ++++ KY  +   + +MIG+G+Q  V++ + N  E   K+I +    L+ I++EV++S+ F H N++ ++ ++ +D    D   I I+ PLMK +L +Y+  N+++++ ++KI++E+A  L Y+H Q ++H+DLKL NIL+   ++V ++DYGFCKS+ ++ Y+     +H+APE V+  ++ +KIDIY++G+LLWYL +G    P  A C  T  +V+ E +    +  ++PE++   PD +W LM+ECW  +P +RP+ ++II+ +Q
Sbjct:  101 ENPTIAIVGSVKAGKSTLVNLLLRKNVVRQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKN-KPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILSENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKF----CQKHIIDLICKDLDNLIDNFVQDELNKNFENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTF--------DINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVT----NKNVRPERLENIPDNLWDLMNECWDQNPSNRPNINSIISTIQ 922
[Close]
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000056716.1 (SMESG000056716.1)

HSP 1 Score: 561.222 bits (1445), Expect = 0.000e+0
Identity = 310/839 (36.95%), Postives = 518/839 (61.74%), Query Frame = 2 
Query:  395 ENPVIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELIDSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLESGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADLLELISVCPNIEIIYFITHLDGEDLDSETANP-IAISQRKMELSFRKLQYHNFIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFETILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSXXXXXXXXXXXXXXXXXXMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSIQIPENGIV---NDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVXXXXXXXXXXXXXXYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQSVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKCDHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKILNNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIVIKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSD----DGKSIQIFYPLMKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILISSNDSVCISDYGFCKSMVIAFYN-ERMPIHVAPE-VKMKEFTKKIDIYAYGILLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKIWQLMSECWSNHPDDRPDTDTIINELQ 2881
            ENP I ++G +K GKST +N+LLRK++V Q+   CT R+TRI+YSE N++EL++   ++IE+K  ++ K +    ++LN  +R NP+E++K++++G+K+KFL+SGID+IDSPG+     L  L   ++  VLPV+IYVIDG+  VKQTD +++L L    PN+ IIYFIT LD +D+     N  I  ++ K++ +FRKLQ  N IP ++  YS+C  FHGASL   ++   K  SQE  +H EQF KF+ D   ILS  F  +I  + ++L+DFQ+ + TKII++A+ F   T +N+++I  ++K+E+ +++ +K  I++SK  LI+RL+ RL ++S  II+ I D  +P SI IPEN      N  F    CQ+ I+ ++ + L+N++  FV++EL +N++N  +  +   I +    Y    + K+ Y + LER L + YK D L     + + S+     N++    +  LSN  F        ++ +  W++ Q K  L  CD  LLA+ +C ++  D  +KH  F  N+  E   I+KE+   E IR KI N    F  L +  ++++ KY  +   + +MIG+G+Q  V++ + N  E   K+I +    L+ I++EV++S+ F H N++ ++ ++ +D    D   I I+ PLMK +L +Y+  N+++++ ++KI++E+A  L Y+H Q ++H+DLKL NIL+   ++V ++DYGFCKS+ ++ Y+     +H+APE V+  ++ +KIDIY++G+LLWYL +G    P  A C  T  +V+ E +    +  ++PE++   PD +W LM+ECW  +P +RP+ ++II+ +Q
Sbjct:  102 ENPTIAIVGSVKAGKSTLVNLLLRKNVVRQAHKTCTARLTRITYSEENYVELVNIHDQIIERKKLKN-KPIPKYIVELNDEDRSNPDEVNKLIRVGIKSKFLKSGIDLIDSPGLNENHVLNLLISNIINKVLPVMIYVIDGQTSVKQTDISNILSLKVSIPNLNIIYFITRLDTDDVSELIENDHIKTAKDKLDFTFRKLQRSNLIPKTFNHYSECHNFHGASLYSYMDYCNKIKSQETDFHNEQFCKFESDLNRILSENFEREILTATKSLIDFQMDVLTKIISRAKQFVDFTNENLDEIFTMRKVEERLHNDLKSEINNSKPLLIDRLMKRLDNESDLIIDLIADMEFPKSIIIPENKAFTKKNAKF----CQKHIIDLICKDLDNLIDNFVQDELNKNFENCFEAHLSPKIINKLKLYSCRLSNKSPYRLCLERNLTKYYKYDLLGLKIKNSSFSIWNFLKNIITGLFRSDLSNDTF--------DINSRHWRIGQTKIILNLCDKDLLAKNICNNMLHDLNVKHDRFLMNLEKEFKVIQKEINLSETIRDKISNETSSFTLLLMRTLDLQSKYLMKDSVEKEMIGQGSQGTVYRCVCNGKEYAKKKIIVPTDLLETISEEVYYSYLFEHPNLLPLIAVTVNDNIRFDCIEISIYTPLMKIDLENYMKKNILTLEQQLKISLEVANALKYIHNQNIMHRDLKLANILLDEQNNVYLADYGFCKSLALSNYSFVGTFVHIAPEIVRQSKYDQKIDIYSFGMLLWYLAKGDCEPPLFANCQSTTVKVLLEVT----NKNVRPERLENIPDNLWDLMNECWDQNPSNRPNINSIISTIQ 923
The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DSTYK2.508e-2624.72dual serine/threonine and tyrosine protein kinase ... [more]
MATK8.076e-2528.35megakaryocyte-associated tyrosine kinase [Source:H... [more]
MATK8.502e-2527.48megakaryocyte-associated tyrosine kinase [Source:H... [more]
MATK1.218e-2427.76megakaryocyte-associated tyrosine kinase [Source:H... [more]
MATK1.218e-2427.76megakaryocyte-associated tyrosine kinase [Source:H... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlk-15.516e-2131.61Mitogen-activated protein kinase kinase kinase dlk... [more]
dlk-11.431e-2031.61Mitogen-activated protein kinase kinase kinase dlk... [more]
dlk-11.462e-2031.61Mitogen-activated protein kinase kinase kinase dlk... [more]
dlk-11.503e-2031.61Mitogen-activated protein kinase kinase kinase dlk... [more]
ZK622.14.442e-2026.44Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Src64B6.939e-2027.64gene:FBgn0262733 transcript:FBtr0343995[more]
Src64B7.219e-2027.64gene:FBgn0262733 transcript:FBtr0100508[more]
Src64B7.219e-2027.64gene:FBgn0262733 transcript:FBtr0100505[more]
Src64B7.219e-2027.64gene:FBgn0262733 transcript:FBtr0100504[more]
Src64B7.219e-2027.64gene:FBgn0262733 transcript:FBtr0304990[more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dstyk1.009e-2627.46dual serine/threonine and tyrosine protein kinase ... [more]
dstyk1.127e-2627.46dual serine/threonine and tyrosine protein kinase ... [more]
matk4.760e-2628.69megakaryocyte-associated tyrosine kinase [Source:Z... [more]
matk5.984e-2628.69megakaryocyte-associated tyrosine kinase [Source:Z... [more]
map3k123.953e-2329.63mitogen-activated protein kinase kinase kinase 12 ... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dstyk4.716e-2723.88dual serine/threonine and tyrosine protein kinase ... [more]
dstyk5.237e-2723.88dual serine/threonine and tyrosine protein kinase ... [more]
dstyk5.377e-2723.88dual serine/threonine and tyrosine protein kinase ... [more]
dstyk5.406e-2723.88dual serine/threonine and tyrosine protein kinase ... [more]
dstyk5.416e-2723.88dual serine/threonine and tyrosine protein kinase ... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dstyk3.302e-2624.58dual serine/threonine and tyrosine protein kinase ... [more]
Matk6.471e-2527.41megakaryocyte-associated tyrosine kinase [Source:M... [more]
Matk6.471e-2527.41megakaryocyte-associated tyrosine kinase [Source:M... [more]
Matk6.701e-2527.41megakaryocyte-associated tyrosine kinase [Source:M... [more]
Matk6.701e-2527.41megakaryocyte-associated tyrosine kinase [Source:M... [more]
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BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A2CI35|DUSTY_STRPU4.953e-2824.76Dual serine/threonine and tyrosine protein kinase ... [more]
sp|Q4TVR5|DUSTY_BOVIN9.098e-2724.86Dual serine/threonine and tyrosine protein kinase ... [more]
sp|Q67E01|DUSTY_XENLA9.666e-2724.16Dual serine/threonine and tyrosine protein kinase ... [more]
sp|Q4VSN2|DUSTY_TAKRU1.025e-2627.40Dual serine/threonine and tyrosine protein kinase ... [more]
sp|Q4VSN3|DUSTY_TETNG1.958e-2626.99Dual serine/threonine and tyrosine protein kinase ... [more]
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BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FM291.288e-8227.44Protein kinase domain-containing protein OS=Macros... [more]
A0A2B4SY007.325e-7626.34Dual serine/threonine and tyrosine protein kinase ... [more]
A0A267FZS18.011e-7225.91Protein kinase domain-containing protein (Fragment... [more]
A0A3M6TL502.559e-7125.37Protein kinase domain-containing protein OS=Pocill... [more]
A0A1S3JVK32.585e-6825.61dual serine/threonine and tyrosine protein kinase ... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
matk7.379e-2528.69megakaryocyte-associated tyrosine kinase [Source:N... [more]
matk1.464e-2428.69megakaryocyte-associated tyrosine kinase [Source:N... [more]
map3k122.223e-2330.26mitogen-activated protein kinase kinase kinase 12 ... [more]
map3k122.384e-2330.26mitogen-activated protein kinase kinase kinase 12 ... [more]
si:ch211-45c16.21.410e-2128.68mitogen-activated protein kinase kinase kinase 13 ... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008193.17.709e-2428.57pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-... [more]
frk1.135e-1826.52fyn-related Src family tyrosine kinase [Source:ZFI... [more]
ENSPMAT00000009736.12.386e-1721.79pep scaffold:Pmarinus_7.0:GL479388:5844:12989:-1 g... [more]
clul14.198e-1725.51clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GE... [more]
ENSPMAT00000004129.16.159e-1725.10pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
MKK17.265e-1226.94MAPKK involved in the protein kinase C signaling p... [more]
PHO851.965e-1122.31Cyclin-dependent kinase; has ten cyclin partners; ... [more]
PKC12.724e-1133.96Protein serine/threonine kinase; essential for cel... [more]
CLA42.800e-1134.78Cdc42p-activated signal transducing kinase; member... [more]
BCK15.348e-1125.48MAPKKK acting in the protein kinase C signaling pa... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO498151.078e-2833.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO444587.858e-2823.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO375754.051e-2727.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO498164.066e-2639.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495802.597e-2227.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dstyk3.176e-2827.87dual serine/threonine and tyrosine protein kinase ... [more]
matk5.004e-2429.91megakaryocyte-associated tyrosine kinase [Source:N... [more]
matk5.004e-2429.91megakaryocyte-associated tyrosine kinase [Source:N... [more]
MAP3K129.157e-2329.63mitogen-activated protein kinase kinase kinase 12 ... [more]
MAP3K129.920e-2329.63mitogen-activated protein kinase kinase kinase 12 ... [more]
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BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000056722.10.000e+099.78SMESG000056722.1[more]
SMESG000056697.10.000e+042.58SMESG000056697.1[more]
SMESG000056719.10.000e+040.29SMESG000056719.1[more]
SMESG000056716.10.000e+036.95SMESG000056716.1[more]
SMESG000056716.10.000e+036.95SMESG000056716.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016907 ID=SMED30016907|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2947bp
GATGGTTTATTATTTGAATGCCGTTCGTGTATCGATTGGTGTATAAATGT
GCACAGTGATAATCATTCACGATTTCCGTTTTAAGTTTTATTATTTATCA
TAAATGTTGCGAAATTCCTTCATAAGTCGATTTTCGAAGCGGAGACTTTC
TGTCAACAAAGACTACGACACAGAACTTTCGAAATGTATTTATAAATATC
GTCAAAGCAGAGAAGAATTAATTTCTTCAATCAATGAAACAATAAAATTA
TTCGACGAGTTTTTAACTGAACCGATTCCGGAAATTATTGAAACATTCGA
TAGGAAGAGTCTCATTGATCTGAAAACGGAACTAGGTGAAAGGTCAGGAC
CGAAAATGCAAGAGATTGAGCTTATTAGAGAAAATATTTCTCTTGAAAAT
CCCGTTATAATTGTTCTCGGCCAATTGAAAACCGGGAAAAGTACATTTAT
CAATATTTTGTTGAGAAAAGATCTAGTTCCTCAGAGTTTTGACGTGTGTA
CTAACAGAGTAACGAGGATTTCTTATAGCGAAAACAATTTCATCGAACTC
ATTGATTCGGATGGTCGAGTGATTGAGAAAAAACATTTTCGGAGTCACAA
GAGCGTTCTATCAAAATTTATCAAGCTCAATTTGAACGAAAGACAAAATC
CAAATGAAATAAGCAAAGTTGTGAAAATTGGCGTTAAAAACAAATTCCTT
GAATCGGGAATTGATATAATCGATTCACCTGGAATGGAAACCTTTGACTA
TCTCACATTTCTCAGGAAATATATGGTGAAAAATGTATTGCCGGTGGTTA
TTTATGTGATTGACGGACGAGCTGGGGTTAAACAAACCGATACTGCAGAC
TTATTAGAACTAATAAGTGTTTGTCCAAATATTGAAATAATTTATTTCAT
AACCCATCTGGATGGGGAGGATCTAGATTCAGAAACAGCTAATCCTATAG
CAATATCTCAACGGAAAATGGAACTGTCATTCAGAAAATTACAATACCAT
AATTTTATTCCATCCTCGTACAAAACATATAGTCAATGTCCTTATTTCCA
TGGAGCATCTCTAAAATGTCTCATAGAAGCCAGTCAGAAACAATCAAGTC
AAGAAATCACTTATCATTTGGAACAATTCCAAAAATTTCAAAGAGATTTT
GAAACTATATTATCCATTTATTTTAGAAATAAAATCTTTGAATCGTGCGA
AACGCTAATGGATTTCCAAATTGGAATGTCTACAAAAATAATCAACCAAG
CAGAAAACTTTAAGTCTAAAACTAAAAAAAACATCGAACAAATAAAACAA
ATAAAAAAAATAGAAAAAGAAATGTATTCAAAAATTAAAATGGCAATTTC
TGATTCGAAAGGCGACCTGATTAATCGGCTGATCAACAGATTAAAGAGTC
AATCAAAAGAGATAATAAATCCAATAATTGACACAATTTATCCAAATTCA
ATTCAGATCCCTGAAAATGGAATAGTAAATGATCCGTTTATTGTCGATCA
ATGCCAAAGAACTATTATGAAGATATTGATCCAAGGTTTGGAAAATGTTT
TGAAAACATTTGTTGAAGAAGAACTGTTTCAAAACTACCAAAATGCTGTC
AAAGATAAAATATTTAAAAGCATCAAAGACATTAAGGACAGCTATGAATA
TCCCAAAAATGGGAAAACTTCATATTTAATTTCCCTTGAACGGATCTTAA
ACAGAAATTACAAATTAGATAGATTATCAACAGTTTCGACAGACGGAAAT
CAAAGTGTCGTTTTCGAGTTTATGAATGTCGTACTATCAAGCGTTAAAGG
CTTCCTCTCTAACGGCCTATTTATGGAATTAAATGAAAACCAAGTTAACG
TGAAGAACCCTGAATGGAAACTGAATCAAGCTAAAGAGTACTTGAAAAAA
TGTGATCACCATTTATTAGCAGAAGAAGTTTGTAAAAGTTTATTTGAAGA
TTTTGAAATCAAGCATAAAACCTTTAAGCGGAATATAATTTCTGAGTCGA
ATTTTATTAAAAAAGAAGTTGTAACTTTAGAAAAGATTCGCACAAAAATC
CTCAATAATGCTCCACGTTTTTATCCACTGTTTCTTAATATCGTCAATAT
TGAAGGAAAATATAAGTTCGAATATGTTTCAAAAACAGATATGATTGGAA
AAGGGGCTCAAAGTGAAGTTTTTAAAGGGATATACAATAACGCAGAGATA
GTGATCAAAGAAATTAAGCTGAATGTATATACTTTGGATAATATTGCAAA
AGAAGTCTTTCATTCACATCGATTTTCACATGAAAATATTATGACTATTC
TCGGAATTTCAAAATCAGATGATGGAAAGTCTATTCAAATATTTTATCCA
TTAATGAAATCAAATTTACGTGATTACATTAATTACAATGTTATAAGTAT
GAAAAATAAAATAAAAATTGCCATGGAAATAGCTGAAGGACTGCATTATT
TACACGAACAAGAAGTTATCCATCAGGATCTTAAGTTGCCAAATATTTTG
ATCAGCTCAAATGATTCAGTTTGTATATCTGACTACGGGTTCTGTAAATC
CATGGTAATAGCCTTTTATAATGAAAGAATGCCCATCCATGTAGCTCCAG
AAGTTAAAATGAAAGAATTTACGAAAAAAATCGACATATATGCTTACGGC
ATATTATTGTGGTATTTGTTTGAAGGTTCTGGCAGAGAACCCAAAGGAGC
TATTTGTTTGAAGACACTAAACCAAGTTGTATGGGAAAATTCTATATTCG
ATAATGATTTTCAGATGAAGCCAGAAAAGATTAACAAATTTCCAGATAAA
ATTTGGCAGTTAATGTCAGAGTGCTGGAGCAATCACCCGGATGATCGACC
TGATACCGATACCATTATTAATGAATTACAGATTTTCGAATAAACGAACT
ATTTTCTTAAAAGATCTTTAATAAAGTTGACAAAAGCTTAGTTTATA
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protein sequence of SMED30016907-orf-1

>SMED30016907-orf-1 ID=SMED30016907-orf-1|Name=SMED30016907-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=930bp
MLRNSFISRFSKRRLSVNKDYDTELSKCIYKYRQSREELISSINETIKLF
DEFLTEPIPEIIETFDRKSLIDLKTELGERSGPKMQEIELIRENISLENP
VIIVLGQLKTGKSTFINILLRKDLVPQSFDVCTNRVTRISYSENNFIELI
DSDGRVIEKKHFRSHKSVLSKFIKLNLNERQNPNEISKVVKIGVKNKFLE
SGIDIIDSPGMETFDYLTFLRKYMVKNVLPVVIYVIDGRAGVKQTDTADL
LELISVCPNIEIIYFITHLDGEDLDSETANPIAISQRKMELSFRKLQYHN
FIPSSYKTYSQCPYFHGASLKCLIEASQKQSSQEITYHLEQFQKFQRDFE
TILSIYFRNKIFESCETLMDFQIGMSTKIINQAENFKSKTKKNIEQIKQI
KKIEKEMYSKIKMAISDSKGDLINRLINRLKSQSKEIINPIIDTIYPNSI
QIPENGIVNDPFIVDQCQRTIMKILIQGLENVLKTFVEEELFQNYQNAVK
DKIFKSIKDIKDSYEYPKNGKTSYLISLERILNRNYKLDRLSTVSTDGNQ
SVVFEFMNVVLSSVKGFLSNGLFMELNENQVNVKNPEWKLNQAKEYLKKC
DHHLLAEEVCKSLFEDFEIKHKTFKRNIISESNFIKKEVVTLEKIRTKIL
NNAPRFYPLFLNIVNIEGKYKFEYVSKTDMIGKGAQSEVFKGIYNNAEIV
IKEIKLNVYTLDNIAKEVFHSHRFSHENIMTILGISKSDDGKSIQIFYPL
MKSNLRDYINYNVISMKNKIKIAMEIAEGLHYLHEQEVIHQDLKLPNILI
SSNDSVCISDYGFCKSMVIAFYNERMPIHVAPEVKMKEFTKKIDIYAYGI
LLWYLFEGSGREPKGAICLKTLNQVVWENSIFDNDFQMKPEKINKFPDKI
WQLMSECWSNHPDDRPDTDTIINELQIFE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR027417P-loop_NTPase
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR022812Dynamin_SF
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0004712protein serine/threonine/tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0018108peptidyl-tyrosine phosphorylation
GO:0033674positive regulation of kinase activity
GO:0035556intracellular signal transduction
GO:0044344cellular response to fibroblast growth factor stimulus
GO:0045743positive regulation of fibroblast growth factor receptor signaling pathway
GO:0070374positive regulation of ERK1 and ERK2 cascade
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005829cytosol
GO:0005886plasma membrane
GO:0016020membrane
GO:0016323basolateral plasma membrane
GO:0016324apical plasma membrane
GO:0030054cell junction
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 675..928
e-value: 4.9E-18
score: 75.9
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 675..928
score: 30.167
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 670..929
e-value: 1.7E-47
score: 163.7
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 102..351
e-value: 3.1E-17
score: 64.9
NoneNo IPR availablePANTHERPTHR46392FAMILY NOT NAMEDcoord: 24..926
IPR022812Dynamin superfamilyPFAMPF00350Dynamin_Ncoord: 102..252
e-value: 2.9E-14
score: 53.5
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 678..925
e-value: 1.1E-37
score: 129.8
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 788..800
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 660..926
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 86..324