Copine-3
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30016898 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE5 (copine 5 [Source:HGNC Symbol;Acc:HGNC:2318]) HSP 1 Score: 328.946 bits (842), Expect = 7.306e-104 Identity = 203/563 (36.06%), Postives = 307/563 (54.53%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP---------------TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
+KV I+V CR+L PL V+ G E ++ +TE ++ T NPDF + +V+Y FEEKQ L ++ DS S + G F +G I+ + GS +E P+ I + LN+ KP T I+ +E S ++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ I +++N KK+ KK+ Y+NSG + +++ TFLDY+ G +NF VA+D + N Q S+ + Q N Y +A+ AV EI+Q YD+D +FPA GFGA++PPD + HE+PLNG+ +N C G+DG+L AY +L+TV+ F PV+ V A DGS Y VLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D + + LA++VLAE+PDQLV+YMK +
Sbjct: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQ------GMEN-KQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMS-PYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE9 (copine family member 9 [Source:HGNC Symbol;Acc:HGNC:24336]) HSP 1 Score: 322.398 bits (825), Expect = 7.655e-102 Identity = 192/543 (35.36%), Postives = 310/543 (57.09%), Query Frame = 1
Query: 13 SKVIISVGCRHL-PLEVIRAY--RVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQ----EKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+K+ I+V CR+L L+ V L ++ +TE ++ T NPDF + V++Y FEEKQ L ++ DS + + G F +G +I GS ++E L + K T ++ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ + +DWD D D IGE + + L +++N + +++N +K+ KK+ Y+NSG + +++ +TF+DY+ G LNF VA+D + N Q S+ + Q + Y +A+KAV EI+Q+YD+D LFPA+GFGA++PP+ + H++PLN + ++ C G++GVL +Y +L+TV+ F PVI QV A + DGS Y+VLLI+T+G + D +TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+QL++YM+ D++
Sbjct: 14 TKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGS-----RVERT-LTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD--------RDGSHD-FIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGN-PLQPTSLHYMS-PYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 320.087 bits (819), Expect = 7.689e-101 Identity = 193/549 (35.15%), Postives = 304/549 (55.37%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
++V +SV CR+L P+ V+ V G ++ +TE ++ T NPDF + +++Y FEE++ L ++ DS S + G F +G I+ + GS +E PI K T I+ +E + ++ +M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y NSG + +++ +FLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+ LNG+ QN +C G++GV+ AY +LK+V+ F PVI V A DGS YFVLLI+T+G + D +TK +++ AS LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D S + LAK+VLAE+P+Q ++YM+ ++
Sbjct: 24 TRVEVSVSCRNLLDRDTFSKSDPICVLYVQGV-------GNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPG-----KKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGN-PAQPTSLHYMN-PYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 545
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 316.62 bits (810), Expect = 1.017e-99 Identity = 183/501 (36.53%), Postives = 286/501 (57.09%), Query Frame = 1
Query: 127 KTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+TE ++ T NPDF + +++Y FEE++ L ++ DS S + G F +G I+ + GS +E PI K T I+ +E + ++ +M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y NSG + +++ +FLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+ LNG+ QN +C G++GV+ AY +LK+V+ F PVI V A DGS YFVLLI+T+G + D +TK +++ AS LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D S + LAK+VLAE+P+Q ++YM+ ++
Sbjct: 53 RTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPG-----KKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGN-PAQPTSLHYMN-PYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 533
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE2 (copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]) HSP 1 Score: 303.138 bits (775), Expect = 1.637e-94 Identity = 192/494 (38.87%), Postives = 285/494 (57.69%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTF--IIKLKEDSVKKNNFM-MKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVI-IQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCD---GSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
NP F+ + V++Y FEE Q L +F QD +S ++ H F +G+ + G+I KI + L + +KP +I + + N + + ++G LDKKDLFGKSDP++ +K D GKW+ +RTE+IK L+P WK + L LCDGD+ K I C+D+D G + IGE + + E+ ++ + + IN KKQ+KK++Y NSG I + + ++Y+FLDY+ G L F V +D + N D S+ N +NEY AI AV +I+Q+YD+D +FPA GFGAQ+PPD+K HE+ +N + N FC GVDG+ +AY L ++ F+P++ V A + + YF+LLI+T+G + D ET+ AV++AS LP+SII+VG+G+ F M+ LD D +L+ E+A+RD VQFVP R+F R AA K LAK VLAELP Q+V Y K ++
Sbjct: 72 NPAFSKKFVLDYHFEEVQKLKFALFDQDKSSM-RLDEHDF--LGQFSCSLGTIVSSKKI-TRPLLLLNDKPAGKGLITIAAQELSDNRVITLSLAGRRLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGH---------DFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDP-SSLHYIN-PMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREF-RNAA---------KETLAKAVLAELPQQVVQYFKHKNL 540
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9]) HSP 1 Score: 239.195 bits (609), Expect = 6.015e-70 Identity = 174/513 (33.92%), Postives = 258/513 (50.29%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSAS-QEKIYGHCFSNMGRI------IHNGGSIEVPI----KIESNELNNMKNKPTFIIKL-KEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFD---WDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYIN-SGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHC-DGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAAD---GSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDN 1629
NP FT ++ Y FEE Q+L I+ DS + + + H F +GR I + +++ + +I + N KN T I + E+ K + G LDKKD FGKSDPY+ +K D G +RTE+ L+P W ++ I LC D ++ I+ C+D W E D D+LIG + T L+ ++ V I L N KK+ KK SG ++I + TFLD++ G L+F VAVD + N + S F + N+YE+A+++V+ I Q Y++ F AFGFGA++P +PL+ + G+ GV+ AY+ AL V+ F P+I V A+ D + Y +LLI+T+G + D T R++I AS LP+SII++G+G+ F M LD D LL+ + A RD VQFV MR+FL I+ N LA+EVL E+P QL YMKQ + + D+
Sbjct: 80 NPQFTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDF--LGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTKTGSITIYAEEDEKAEKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFDDGSTHLIHRTEVKPKTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKGEEPRGDAKFSRDDLIGTAQTTLNELLRGSSDAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTAS--NGPPKSSSSLHFMSADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQEN---LAREVLYEVPAQLTGYMKQRGFQPRPVDD 585
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9]) HSP 1 Score: 234.187 bits (596), Expect = 3.067e-68 Identity = 172/510 (33.73%), Postives = 257/510 (50.39%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSAS-QEKIYGHCFSNMGRI------IHNGGSIEVPI----KIESNELNNMKNKPTFIIKL-KEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYIN-SGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHC-DGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAAD---GSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDN 1629
NP FT ++ Y FEE Q+L I+ DS + + + H F +GR I + +++ + +I + N KN T I + E+ K + G LDKKD FGKSDPY+ +K D G +RTE+ L+P W ++ I LC D ++ I+ C+D D + D +LIG + T L+ ++ V I L N KK+ KK SG ++I + TFLD++ G L+F VAVD + N + S F + N+YE+A+++V+ I Q Y++ F AFGFGA++P +PL+ + G+ GV+ AY+ AL V+ F P+I V A+ D + Y +LLI+T+G + D T R++I AS LP+SII++G+G+ F M LD D LL+ + A RD VQFV MR+FL I+ N LA+EVL E+P QL YMKQ + + D+
Sbjct: 80 NPQFTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDF--LGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTKTGSITIYAEEDEKAEKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFDDGSTHLIHRTEVKPKTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKD---------DLIGTAQTTLNELLRGSSDAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTAS--NGPPKSSSSLHFMSADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQEN---LAREVLYEVPAQLTGYMKQRGFQPRPVDD 573
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422]) HSP 1 Score: 230.72 bits (587), Expect = 6.573e-67 Identity = 166/505 (32.87%), Postives = 258/505 (51.09%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSAS-QEKIYGHCFSNMGRI--------------IHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENN--TVIIQLINHKKQKKKRSYI-NSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQV-NSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADG---SKTIRWNKVALAKEVLAELPDQLVAYMKQ 1599
NP F + ++ Y FEE Q+ ++ DS + GH F +GR H GG + + ++ + + + I+ +ED K + G LD+KD FGKSDPY+ ++ D G ++TE+ LNP W ++ I LC ++++ I+ C+D + + + D++IG + T LIE + I LIN KK+ KK + NSG ++I + TFLD++ G L+F VAVD + N + + T N+YE+A+++V+ I Q Y++ F A+GFGA++P +PL+ + Q++ G++GV+ AY+ AL+ V F+P+I +V N K + Y +LLI+T+G + D T VI AS LP+SII++G+G+ F M LD D LL+ + A RD VQFV MR FL + G + TI N LA+EVL E+PDQL YMK+
Sbjct: 81 NPQFKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDF--LGRFECVLAQIVSYSTLRAHLGGKHSIGAQWKNKD--KVSKNGSITIRAEEDE-KNEKIQFDVCGEKLDRKDFFGKSDPYLNFKRRFDDGSSHMIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFK--------KQDDIIGTAQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGN--PRTPGSLHYMATGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMEN---LAREVLYEVPDQLTGYMKR 567
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422]) HSP 1 Score: 230.72 bits (587), Expect = 6.573e-67 Identity = 166/505 (32.87%), Postives = 258/505 (51.09%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSAS-QEKIYGHCFSNMGRI--------------IHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENN--TVIIQLINHKKQKKKRSYI-NSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQV-NSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADG---SKTIRWNKVALAKEVLAELPDQLVAYMKQ 1599
NP F + ++ Y FEE Q+ ++ DS + GH F +GR H GG + + ++ + + + I+ +ED K + G LD+KD FGKSDPY+ ++ D G ++TE+ LNP W ++ I LC ++++ I+ C+D + + + D++IG + T LIE + I LIN KK+ KK + NSG ++I + TFLD++ G L+F VAVD + N + + T N+YE+A+++V+ I Q Y++ F A+GFGA++P +PL+ + Q++ G++GV+ AY+ AL+ V F+P+I +V N K + Y +LLI+T+G + D T VI AS LP+SII++G+G+ F M LD D LL+ + A RD VQFV MR FL + G + TI N LA+EVL E+PDQL YMK+
Sbjct: 81 NPQFKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDF--LGRFECVLAQIVSYSTLRAHLGGKHSIGAQWKNKD--KVSKNGSITIRAEEDE-KNEKIQFDVCGEKLDRKDFFGKSDPYLNFKRRFDDGSSHMIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFK--------KQDDIIGTAQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGN--PRTPGSLHYMATGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMEN---LAREVLYEVPDQLTGYMKR 567
BLAST of Copine-3 vs. Ensembl Celegans
Match: cpna-5 (Copine family protein 5 [Source:UniProtKB/Swiss-Prot;Acc:Q09219]) HSP 1 Score: 179.489 bits (454), Expect = 4.287e-48 Identity = 140/511 (27.40%), Postives = 241/511 (47.16%), Query Frame = 1
Query: 160 FTSQLVVEYVFEEKQILAATIFY-----QDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTF-----------IIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFK--KSDKGK----WIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINK--EILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLA-KEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLK 1617
FT + +YVFE+ Q++ A + S+S I + +I GS + ++ + + N+ + + II E K+ +++ G LD+KD D + F+ + ++GK + Y +E +KN+ +P W + D + N+ EI D DG EG IG+ + T + + + +IN K+ +K+SY NSGK++++ + Y+FLDY+ SG L+F + VD S P E + + R E +AI+A+ I+++Y + LF AFG GA+IPP F E +E+ LN + C+G+DGV+ AY+ V + + +PVI V ++ + G HY VL + T G V D E ++A+ AS P+SI+++G+G F+ ++ L + RD VQF+ ++ L +G++ NK +A+ L +P +V YM ++ K
Sbjct: 114 FTDKFSYQYVFEKTQLIKAVFSRCHDRDKPSSSSRDILATSIFKVDELI---GSFGLQLRRQLEKNGNIASALSGTQRVTDEYLGGIIVSAEMPEKEQPIVVQFHGKSLDRKDFLW--DETAVFFRVFRLEEGKDDDSLVFLYESEALKNHSHPQWAEFRLDTQDAAD-NRNRLLEIWVMYKDVDGKEG-----------YIGKFLTTYAKMKYGPGSDNVYSVINDVKKAQKKSYENSGKMELVKFTDVSFYSFLDYIVSGTQLHFEIGVDFSSP--------EPVHELDQRRFDGELHMAIRAIGSIIRDYTPNRLFAAFGIGAKIPPTFHESNEFFLNFSM-DPICRGLDGVMEAYRKTQTMVTPLKESKLSPVINYVTRMSHRSGFRGLHYHVLALFTRGEVTDLKEIQQALNSASDAPLSILIIGMGDFDFSSLQKLCSK-------RKDGRRDVVQFIHLKSLL----NGAEAPWLNKSRIAETALRHVPQHMVQYMHNANIAAK 587
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5a (copine Va [Source:ZFIN;Acc:ZDB-GENE-081105-9]) HSP 1 Score: 342.043 bits (876), Expect = 1.941e-109 Identity = 202/549 (36.79%), Postives = 307/549 (55.92%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CR+L PL ++ G E ++ +TE ++ T NPDF + +++Y FEEKQ L I+ DS S + G F +G I+ + GS +E P+ KN T I+ +E ++ M+ LDKKD FG+SDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KKR YINSG + +++ +TFLDY+ +G+ ++F VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ N +C G++G+L AY +LKTV+ F PVI V A DGS YFVLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQL+ YMK ++
Sbjct: 23 TKVEITVSCRNLLDRDTFSKSDPLCILYTQ------GAES-KQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDIYDIDSKSPDLAKHDFLGQTFCTLGEIVGSPGSRLEKPLGGIPG-----KNCGTIILTAEELGNCRDCATMQFCANKLDKKDFFGRSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPIWQPFTIPVRALCNGDYDRSIKVEVYDWD--------RDGSHD-FIGEFTTSYRELSRGQSQFNVYEVVNPKKKLKKRRYINSGTVTLLSFLVEAEHTFLDYIKAGLQIHFTVAIDFTASNGN-PSQSTSLHYMN-PYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVDNPYCNGMEGILEAYHESLKTVQLYGPTNFAPVINHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQLILYMKSRGIK 544
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398]) HSP 1 Score: 330.872 bits (847), Expect = 2.910e-105 Identity = 199/550 (36.18%), Postives = 310/550 (56.36%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CR+L PL V+ V ++ +TE ++ T NPDF + +++Y FEEKQ L ++ DS S + G F +G I+ + S +E P+ S KN T ++ +E +++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y+NSG + +++ FS+++ TFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ +N +C G++G+L AY +LKTV+ F PV+ V A DGS YF+LLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQ ++YMK ++
Sbjct: 23 TKVEITVSCRNLLDRDTFSKSDPLCVLYTQGVET-------KQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIVGSPASRLEKPLGGISG-----KNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLS-FSVESESTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQFISYMKSRGIK 544
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398]) HSP 1 Score: 328.561 bits (841), Expect = 3.371e-104 Identity = 200/556 (35.97%), Postives = 313/556 (56.29%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQE-------KIY---GHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CR+L PL V+ V ++ +TE ++ T NPDF + +++Y FEEKQ L ++ DS S + ++Y G F +G I+ + S +E P+ S KN T ++ +E +++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y+NSG + +++ FS+++ TFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ +N +C G++G+L AY +LKTV+ F PV+ V A DGS YF+LLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQ ++YMK ++
Sbjct: 28 TKVEITVSCRNLLDRDTFSKSDPLCVLYTQGVET-------KQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHKPLELYDFLGQMFCTLGEIVGSPASRLEKPLGGISG-----KNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLS-FSVESESTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQFISYMKSRGIK 555
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne8 (copine VIII [Source:ZFIN;Acc:ZDB-GENE-100809-1]) HSP 1 Score: 322.783 bits (826), Expect = 5.102e-102 Identity = 197/575 (34.26%), Postives = 317/575 (55.13%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQ----EKIYGHCFSNMGRIIHNGGSIEVPIKIESNELN-NMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPVHKQYDNFKSP-KELQHQ 1686
+KV I+V CR+L P+ V+ V ++ +TE ++ T NPDF + +++Y FEE+Q L ++ DS S+ G + +G ++ + GS ++E + + KN T I+K +E + + +M+ G LDKKD FGKSDP+++ ++ ++ G + ++TE++KN L+P W++ I + LC+GD ++ I +DWD G + IGE + + L + + +++N KK+KKK+ Y+NSG + +++ F TFLDY+ G +NF VA+D + N Q S+ + N Y +A++AV EI+Q+YD+D LFPA GFGA++PPD + HE+PLNG+ N +C G++GVL AY +LK+V+ F+PVI V A DGS YF+LLI+++G + D +TK +++ ASSLP+SII+VG+G F +M LD D + A RD VQFVP R ++ D + LAK+VLAE+PDQ + Y++ ++ + +S + K + P LQ Q
Sbjct: 27 TKVEITVSCRNLLDRDTFSKSDPICVLYTQTV-------ANREWREFGRTEVIDNTLNPDFVHKFILDYFFEERQNLRFDLYDLDSKSENLSKHDFLGQMYCTLGEVVGSPGS-----RMERSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGH---------DYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGN-PSQPTSLHYMS-PYHLNAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYI----DRRGNHILSMARLAKDVLAEIPDQFLQYVRSRGIKPQHSAHSTISKPPASLVHPIHHLQTQ 574
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne1 (copine I [Source:ZFIN;Acc:ZDB-GENE-030131-3562]) HSP 1 Score: 307.375 bits (786), Expect = 1.356e-96 Identity = 197/544 (36.21%), Postives = 315/544 (57.90%), Query Frame = 1
Query: 13 SKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHK--DTMKTEFLET-SNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNN-FMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAK---EHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLK-VGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
SKV +S+ C +L + + + L V + K + +TE ++ +P F+++L ++Y FE+ Q L ++ D+ S + G +G+I+ + + P+++++ + K T I +E VK N +M++ +LDKKDLFGKSDP++ FK+ + GKW +RTE+IKNNLNP WK + L+ C+GD+NK I C+D D ED + ++IGE T L+E+++N V I+ +KQKKK+SY NSG I+I Y+FLDY+ G +NF V +D + + +S+ N N+Y AI +V +++Q+YD+D LFPAFGFGAQ+PP+F+ HE+PLN + + +C+GV+G++ AY++ L ++ F+P+I V +A + + + YFVLLI+T+G + D +T+++++ +S LP+SII+VG+G F M+ LD D G+LK + E A RD VQFVP ++F K ALA+ VLAE+P QLV Y K ++
Sbjct: 7 SKVELSISCNNLLDKDVGSKSDPLCVLLQSVGDDKWTEVARTERVKNCQDPQFSTKLHIDYYFEKVQKLKFGVYDIDNKSVDLGDDDFLGGFEGTLGQIVSSR-KLTRPLQLKAAK---PAGKGTITITAEE--VKDNRAIVMEIEAKNLDKKDLFGKSDPFLEFFKQDEDGKWQLVHRTEVIKNNLNPSWKKFTVSLHTFCNGDLNKPIKVTCYDKD------EDTSS---DMIGEFTCTTAKLMEAKDNAVEFDCIHPEKQKKKKSYKNSGVIKIKDCKLETQYSFLDYVMGGCQINFTVGIDFTGSNGDPRSP-DSLHYLN-PNGVNQYLSAIWSVGQVVQDYDSDKLFPAFGFGAQVPPNFQVSHEFPLNFNPNSPYCQGVEGIVNAYRSVLPQLRLYGPTNFSPIINHVARIASGAAQQPNAAQYFVLLIITDGEITDLDQTRQSIVNSSKLPMSIIIVGVGEADFKAMEFLDGDNGVLKSITGESAVRDIVQFVPFKQFANAP----------KEALAQSVLAEVPSQLVTYFKMRNL 523
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266]) HSP 1 Score: 335.109 bits (858), Expect = 1.006e-106 Identity = 210/557 (37.70%), Postives = 313/557 (56.19%), Query Frame = 1
Query: 13 SKVIISVGCRHLPLEVIRAYR----VTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS-----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLK-FCDNSPVH 1641
+K+ I+V CR L L++ + V L V G + +TE ++ T NPDF + V++Y FEEKQ L +F DS S + G F +G +I + S +E P L + K T I+ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE+IKN LNP W+ I + LC+GD ++ + +DWD G D IGE + + L ++ + +++N KK+ KK+ YINSG + +++ + YTF+DY+ G LNF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D LFPA+GFGA+IPPD K HE+ LNGD +N C G+ GVL AY +L+TV+ F VI QV A + DGS Y+VLLI+T+G + D ++TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+Q ++YMK D++ + + PV
Sbjct: 17 TKIEITVSCRSL-LDMDTFSKSDPVVVLYVQGVGNKEWTEFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVFNVDSRSCNISKHKDFLGQAFCTLGEVIGSPRSRLEKP-------LTGIPGKKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWD--RGGSHD-------FIGEFTTSYRELSRGQSQFSVYEVLNPKKKCKKKKYINSGTVTLLSFKAESEYTFVDYIKGGTQLNFTVAIDFTASNGN-PSQPTSLHYMN-PYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSRDIKPRPLSQSGPVQ 550
BLAST of Copine-3 vs. Ensembl Xenopus
Match: cpne9 (copine family member IX [Source:NCBI gene;Acc:100125077]) HSP 1 Score: 334.724 bits (857), Expect = 2.087e-106 Identity = 195/517 (37.72%), Postives = 297/517 (57.45%), Query Frame = 1
Query: 127 KTEFLETS-NPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPT---------------FIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+TE ++ S NPDF + V++Y FEEKQ L ++ D+ S + G CF +G I+ + GS +E + I N N+ + T II +E S ++ ++ S LDKKD FGKSDP+++ ++ ++ G + ++TE +KN L+P W+ I + LC+GD ++ I +DWD D D IGE + + L + ++ I ++IN +K+ KK+ YINSG + +++ FS+++ YTFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D FPA GFGA++PPD + HE+PLNG +N C G++G+L AY +LK+V+ F PV+ +V A DGSHYFVLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D + + LAK+VLAE+PDQL++YMK ++
Sbjct: 58 RTEVIDNSLNPDFVRKFVLDYFFEEKQNLRFDLYDVDAKSPDLSKHDFLGQCFCTLGEIVGSAGSRLEKSLIIGQNAPNSRSGRSTQSMSNGGIPSKKCGIIIISAEELSNCRDIATVQFSAHKLDKKDFFGKSDPFMVFYRSNEDGTYTICHKTEYVKNTLSPVWQKFSIPVRGLCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFSTSYRELSKGQSQFNIYEVINPRKKIKKKKYINSGTVTLLS-FSVESEYTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQLNAYALALKAVGEIIQDYDSDKRFPALGFGAKLPPDGRVSHEFPLNGSIENPQCNGIEGILEAYHKSLKSVQLYGPTNFAPVVNRVARFAAAVQDGSHYFVLLIITDGVISDMSQTKEAIVNAAMLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLAKDVLAEIPDQLISYMKARGIK 558
BLAST of Copine-3 vs. Ensembl Xenopus
Match: cpne9 (copine family member IX [Source:NCBI gene;Acc:100125077]) HSP 1 Score: 330.487 bits (846), Expect = 8.174e-105 Identity = 197/519 (37.96%), Postives = 296/519 (57.03%), Query Frame = 1
Query: 127 KTEFLETS-NPDFTSQLVVEYVFEEKQILAATIF---YQD---SASQEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPT---------------FIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+TE ++ S NPDF + V++Y FEEKQ L +F Y D S G CF +G I+ + GS +E + I N N+ + T II +E S ++ ++ S LDKKD FGKSDP+++ ++ ++ G + ++TE +KN L+P W+ I + LC+GD ++ I +DWD D D IGE + + L + ++ I ++IN +K+ KK+ YINSG + +++ FS+++ YTFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D FPA GFGA++PPD + HE+PLNG +N C G++G+L AY +LK+V+ F PV+ +V A DGSHYFVLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D + + LAK+VLAE+PDQL++YMK ++
Sbjct: 53 RTEVIDNSLNPDFVRKFVLDYFFEEKQNLRFDLFAITYFDLNFSLFLFDFLGQCFCTLGEIVGSAGSRLEKSLIIGQNAPNSRSGRSTQSMSNGGIPSKKCGIIIISAEELSNCRDIATVQFSAHKLDKKDFFGKSDPFMVFYRSNEDGTYTICHKTEYVKNTLSPVWQKFSIPVRGLCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFSTSYRELSKGQSQFNIYEVINPRKKIKKKKYINSGTVTLLS-FSVESEYTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQLNAYALALKAVGEIIQDYDSDKRFPALGFGAKLPPDGRVSHEFPLNGSIENPQCNGIEGILEAYHKSLKSVQLYGPTNFAPVVNRVARFAAAVQDGSHYFVLLIITDGVISDMSQTKEAIVNAAMLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLAKDVLAEIPDQLISYMKARGIK 555
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266]) HSP 1 Score: 323.939 bits (829), Expect = 6.385e-103 Identity = 197/512 (38.48%), Postives = 291/512 (56.84%), Query Frame = 1
Query: 127 KTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDS----ASQEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKI--QIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPV 1638
+TE ++ T NPDF + V++Y FEEKQ L +F DS S+ G F +G +I + S +E P+ K T I+ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE+IKN LNP W+ I + LC+GD ++ + +DWD G D IGE + + L ++ + +++N KK+ KK+ YINSG + ++ D ++ TFL + FS LNF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D LFPA+GFGA+IPPD K HE+ LNGD +N C G+ GVL AY +L+TV+ F VI QV A + DGS Y+VLLI+T+G + D ++TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+Q ++YMK D++ P+
Sbjct: 24 RTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVFNVDSRSCNISKHDFLGQAFCTLGEVIGSPRSRLEKPLTGIPG-----KKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWD--RGGSHD-------FIGEFTTSYRELSRGQSQFSVYEVLNPKKKCKKKKYINSGTVTEELDGDSAI---TFLSFFFSRTQLNFTVAIDFTASNGN-PSQPTSLHYMN-PYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSRDIKPPIRQPPPI 512
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266]) HSP 1 Score: 316.62 bits (810), Expect = 2.782e-100 Identity = 195/510 (38.24%), Postives = 288/510 (56.47%), Query Frame = 1
Query: 127 KTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKI--QIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLK-FCDNSPVH 1641
+TE ++ T NPDF + V++Y FEEKQ L F G F +G +I + S +E P+ K T I+ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE+IKN LNP W+ I + LC+GD ++ + +DWD G D IGE + + L ++ + +++N KK+ KK+ YINSG + ++ D ++ TFL + FS LNF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D LFPA+GFGA+IPPD K HE+ LNGD +N C G+ GVL AY +L+TV+ F VI QV A + DGS Y+VLLI+T+G + D ++TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+Q ++YMK D++ + + PV
Sbjct: 24 RTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDDFL----------GQAFCTLGEVIGSPRSRLEKPLTGIPG-----KKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWD--RGGSHD-------FIGEFTTSYRELSRGQSQFSVYEVLNPKKKCKKKKYINSGTVTEELDGDSAI---TFLSFFFSRTQLNFTVAIDFTASNGN-PSQPTSLHYMN-PYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSRDIKPRPLSQSGPVQ 500
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne5 (copine V [Source:MGI Symbol;Acc:MGI:2385908]) HSP 1 Score: 330.872 bits (847), Expect = 8.303e-105 Identity = 204/563 (36.23%), Postives = 308/563 (54.71%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP---------------TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
+KV I+V CR+L PL V+ G E ++ +TE ++ T NPDF + +V+Y FEEKQ L ++ DS S + G F +G I+ + GS +E P+ I + LN+ KP T I+ +E S ++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ I ++IN KK+ KK+ Y+NSG + +++ TFLDY+ G +NF VA+D + N Q S+ + Q N Y +A+ AV EI+Q YD+D +FPA GFGA++PPD + HE+PLNG+ +N C G+DG+L AY ++L+TV+ F PV+ V A DGS Y VLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D + + LA++VLAE+PDQLV+YMK +
Sbjct: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQ------GMEN-KQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMS-PYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne9 (copine family member IX [Source:MGI Symbol;Acc:MGI:2443052]) HSP 1 Score: 322.783 bits (826), Expect = 3.086e-102 Identity = 192/542 (35.42%), Postives = 308/542 (56.83%), Query Frame = 1
Query: 13 SKVIISVGCRHL-PLEVIRAY--RVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQ----EKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+K+ I+V CR+L L+ V L ++ +TE ++ T NPDF + V++Y FEEKQ L ++ DS + + G F +G +I GS +E P+ K T ++ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ + +DWD D D IGE + + L +++N + +++N +K+ KK+ Y NSG + +++ +TF+DY+ G LNF VA+D + N Q S+ + Q + Y +A+KAV EI+Q+YD+D LFPA+GFGA++PP+ + H++PLN + ++ C G++GVL +Y +L+TV+ F PVI QV A + DGS Y+VLLI+T+G + D +TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+QL++YM+ D++
Sbjct: 14 TKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPG-----KKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD--------RDGSHD-FIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGN-PLQPTSLHYMS-PYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne8 (copine VIII [Source:MGI Symbol;Acc:MGI:1914121]) HSP 1 Score: 320.857 bits (821), Expect = 3.399e-101 Identity = 193/550 (35.09%), Postives = 305/550 (55.45%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPI-KIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
++V +SV CR+L P+ V+ V G ++ +TE ++ T NPDF + +++Y FEE++ L ++ DS S + G F +G I+ + GS +E PI I + T I+ +E + ++ +M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y NSG + +++ +FLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+ LNG+ QN +C G++GV+ AY +LK+V+ F PVI V A DGS YFVLLI+T+G + D +TK +++ AS LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D S + LAK+VLAE+P+Q ++YM+ ++
Sbjct: 37 TRVEVSVSCRNLLDRDTFSKSDPICVLYTQAV-------GNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGRKCG------TIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGN-PAQPTSLHYMN-PYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 558
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578]) HSP 1 Score: 299.671 bits (766), Expect = 1.935e-93 Identity = 195/493 (39.55%), Postives = 282/493 (57.20%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTF--IIKLKEDSVKKNNFM-MKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVI-IQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSL--AKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
NP F+ + V++Y FEE Q L +F QD +S + + H F +G+ + G+I KI + L M +KP +I + + N + + ++G LDKKDLFGKSDP++ +K D GKW+ +RTE+IK L+P WK + L LCDGD+ K I C+D+D G + IGE + + E+ + + I+ IN KKQ+KK+SY NSG I + + +NY+FLDY+ G L F V +D + N D S+ N +NEY AI AV +I+Q+YD+D +FPA GFGAQ+PPD+K HE+ +N + N FC GVDG+ +AY L ++ F+P++ V + YF+LLI+T+G + D ET+ AV++AS LP+SII+VG+G+ F M+ LD D L+ E+A+RD VQFVP R+F R AA K LAK VLAELP Q+V Y K ++
Sbjct: 72 NPAFSKKFVLDYHFEEVQKLKFALFDQDKSSAQ-LDEHDF--LGQFSCSLGTIVSSKKI-TRPLLLMNDKPAGKGVITIAAQELSDNRVITLSLAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSNGGH---------DFIGEFQTSVLQMSEARDGVPLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDP-SSLHYIN-PMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREF-RNAA---------KETLAKAVLAELPQQVVQYFKHKNL 539
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578]) HSP 1 Score: 299.286 bits (765), Expect = 2.791e-93 Identity = 196/494 (39.68%), Postives = 284/494 (57.49%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTF--IIKLKEDSVKKNNFM-MKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVI-IQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSL---AKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
NP F+ + V++Y FEE Q L +F QD +S + + H F +G+ + G+I KI + L M +KP +I + + N + + ++G LDKKDLFGKSDP++ +K D GKW+ +RTE+IK L+P WK + L LCDGD+ K I C+D+D G + IGE + + E+ + + I+ IN KKQ+KK+SY NSG I + + +NY+FLDY+ G L F V +D + N D S+ N +NEY AI AV +I+Q+YD+D +FPA GFGAQ+PPD+K HE+ +N + N FC GVDG+ +AY L ++ F+P++ V A + + YF+LLI+T+G + D ET+ AV++AS LP+SII+VG+G+ F M+ LD D L+ E+A+RD VQFVP R+F R AA K LAK VLAELP Q+V Y K ++
Sbjct: 72 NPAFSKKFVLDYHFEEVQKLKFALFDQDKSSAQ-LDEHDF--LGQFSCSLGTIVSSKKI-TRPLLLMNDKPAGKGVITIAAQELSDNRVITLSLAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSNGGH---------DFIGEFQTSVLQMSEARDGVPLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDP-SSLHYIN-PMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREF-RNAA---------KETLAKAVLAELPQQVVQYFKHKNL 540
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q8JZW4|CPNE5_MOUSE (Copine-5 OS=Mus musculus OX=10090 GN=Cpne5 PE=1 SV=1) HSP 1 Score: 330.872 bits (847), Expect = 5.808e-104 Identity = 204/563 (36.23%), Postives = 308/563 (54.71%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP---------------TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
+KV I+V CR+L PL V+ G E ++ +TE ++ T NPDF + +V+Y FEEKQ L ++ DS S + G F +G I+ + GS +E P+ I + LN+ KP T I+ +E S ++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ I ++IN KK+ KK+ Y+NSG + +++ TFLDY+ G +NF VA+D + N Q S+ + Q N Y +A+ AV EI+Q YD+D +FPA GFGA++PPD + HE+PLNG+ +N C G+DG+L AY ++L+TV+ F PV+ V A DGS Y VLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D + + LA++VLAE+PDQLV+YMK +
Sbjct: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQ------GMEN-KQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMS-PYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q9HCH3|CPNE5_HUMAN (Copine-5 OS=Homo sapiens OX=9606 GN=CPNE5 PE=1 SV=2) HSP 1 Score: 328.946 bits (842), Expect = 3.508e-103 Identity = 203/563 (36.06%), Postives = 307/563 (54.53%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP---------------TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
+KV I+V CR+L PL V+ G E ++ +TE ++ T NPDF + +V+Y FEEKQ L ++ DS S + G F +G I+ + GS +E P+ I + LN+ KP T I+ +E S ++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ I +++N KK+ KK+ Y+NSG + +++ TFLDY+ G +NF VA+D + N Q S+ + Q N Y +A+ AV EI+Q YD+D +FPA GFGA++PPD + HE+PLNG+ +N C G+DG+L AY +L+TV+ F PV+ V A DGS Y VLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R ++ D + + LA++VLAE+PDQLV+YMK +
Sbjct: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQ------GMEN-KQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMS-PYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q5BJS7|CPNE9_RAT (Copine-9 OS=Rattus norvegicus OX=10116 GN=Cpne9 PE=2 SV=1) HSP 1 Score: 323.168 bits (827), Expect = 1.568e-101 Identity = 192/542 (35.42%), Postives = 308/542 (56.83%), Query Frame = 1
Query: 13 SKVIISVGCRHL-PLEVIRAY--RVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQ----EKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+K+ I+V CR+L L+ V L ++ +TE ++ T NPDF + V++Y FEEKQ L ++ DS + + G F +G +I GS +E P+ K T ++ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ + +DWD D D IGE + + L +++N + +++N +K+ KK+ Y NSG + +++ +TF+DY+ G LNF VA+D + N Q S+ + Q + Y +A+KAV EI+Q+YD+D LFPA+GFGA++PP+ + H++PLN + ++ C G++GVL +Y +L+TV+ F PVI QV A + DGS Y+VLLI+T+G + D +TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+QL++YM+ D++
Sbjct: 14 TKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPG-----KKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD--------RDGSHD-FIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGN-PLQPTSLHYMS-PYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q1RLL3|CPNE9_MOUSE (Copine-9 OS=Mus musculus OX=10090 GN=Cpne9 PE=1 SV=1) HSP 1 Score: 323.168 bits (827), Expect = 1.879e-101 Identity = 192/542 (35.42%), Postives = 308/542 (56.83%), Query Frame = 1
Query: 13 SKVIISVGCRHL-PLEVIRAY--RVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQ----EKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+K+ I+V CR+L L+ V L ++ +TE ++ T NPDF + V++Y FEEKQ L ++ DS + + G F +G +I GS +E P+ K T ++ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ + +DWD D D IGE + + L +++N + +++N +K+ KK+ Y NSG + +++ +TF+DY+ G LNF VA+D + N Q S+ + Q + Y +A+KAV EI+Q+YD+D LFPA+GFGA++PP+ + H++PLN + ++ C G++GVL +Y +L+TV+ F PVI QV A + DGS Y+VLLI+T+G + D +TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+QL++YM+ D++
Sbjct: 14 TKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPG-----KKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD--------RDGSHD-FIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGN-PLQPTSLHYMS-PYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q8IYJ1|CPNE9_HUMAN (Copine-9 OS=Homo sapiens OX=9606 GN=CPNE9 PE=1 SV=3) HSP 1 Score: 322.398 bits (825), Expect = 3.676e-101 Identity = 192/543 (35.36%), Postives = 310/543 (57.09%), Query Frame = 1
Query: 13 SKVIISVGCRHL-PLEVIRAY--RVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQ----EKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+K+ I+V CR+L L+ V L ++ +TE ++ T NPDF + V++Y FEEKQ L ++ DS + + G F +G +I GS ++E L + K T ++ +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ + +DWD D D IGE + + L +++N + +++N +K+ KK+ Y+NSG + +++ +TF+DY+ G LNF VA+D + N Q S+ + Q + Y +A+KAV EI+Q+YD+D LFPA+GFGA++PP+ + H++PLN + ++ C G++GVL +Y +L+TV+ F PVI QV A + DGS Y+VLLI+T+G + D +TK A++ ASSLP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+P+QL++YM+ D++
Sbjct: 14 TKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGS-----RVERT-LTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD--------RDGSHD-FIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGN-PLQPTSLHYMS-PYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. TrEMBL
Match: A0A4Z2DGU0 (Copine-8 OS=Schistosoma japonicum OX=6182 GN=EWB00_001084 PE=4 SV=1) HSP 1 Score: 530.791 bits (1366), Expect = 7.556e-178 Identity = 258/537 (48.04%), Postives = 367/537 (68.34%), Query Frame = 1
Query: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETS-NPDFTSQLVVEYVFEEKQILAATIFYQDSASQEK--IYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQN 1602
MP K ++ I + CR++P ++++A V + G+ H + +TE + + +P++T+++ +EY FEEKQI+ IF + +E + G+ +GR+IH+GG + +PI + + ++ ++ED K N +KM+G +LDKKD FGKSDPYVI+++++++GK + YR+E+IKN L PDWK I ICL++LC G+I+ E+ RCFDWDGA GD ED+D E+D+LIGE T L+ N + QLIN K+K+K+ Y NSG + + F+ ++FLDY+F G+ +N +VAVDMS S + +++ EYEVAI+AV+EILQEYD+D LFPAFGFGA++ K H YPLNGD N +CKG+ GVL AY+ L + S F P+IR+V+ AK +Y+VLLILTNGTV+DWI+TK+AVIE S LP+SIIV+G+G G F++M+ LDQDFGLLKVG E+A RDNVQFV MR+FLR+AADGS +IRW+KVALAKEVLAELP Q++ Y+ +N
Sbjct: 1 MPHKPRIQIGISCRNIP-KLLKASYAKFSVSYGGYLHERHVTETELVYNNLSPNYTTRINLEYCFEEKQIITTEIFECEREDRENSILLGYIQCTVGRVIHSGGELILPIIWNEDVQVDRSTSTDVVVCIREDPFSKENIFIKMNGANLDKKDFFGKSDPYVIIYRRNERGKLQKCYRSEVIKNTLFPDWKPILICLDRLCGGNIDCELYFRCFDWDGAVGDSEDVDTEIDDLIGEFNTTVSRLLNCNENGIEFQLINMPKKKRKKYYQNSGLLTVKLYFAQSKFSFLDYIFGGLSINVVVAVDMSSHASMNSTTSTSSQQIELSQSHTEYEVAIQAVMEILQEYDSDQLFPAFGFGAKVSSAGKLSHRYPLNGDVNNCYCKGMVGVLSAYRRCLTDLYSSGPIFFAPIIREVSEAAKRSEAADNYYVLLILTNGTVDDWIDTKKAVIETSFLPISIIVLGVGGGKFSEMEILDQDFGLLKVGQEQACRDNVQFVQMRRFLRLAADGSDSIRWSKVALAKEVLAELPSQILEYLDKN 536
BLAST of Copine-3 vs. TrEMBL
Match: A0A3Q0KS66 (Copine, putative OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 524.242 bits (1349), Expect = 4.913e-175 Identity = 259/538 (48.14%), Postives = 370/538 (68.77%), Query Frame = 1
Query: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETS-NPDFTSQLVVEYVFEEKQILAATIFYQDSASQEK--IYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSI-PKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQN 1602
MP K ++ I + CR++P ++++A V + G+ H K +TE + + +P++T++L +EY FEEKQI+ IF + +E + G+ +GR+IH+GG + +PI + + ++ ++ED K N +KM+G +LDKKD FGKSDPYVI+++++++GK + YR+E+IKN L PDWK I ICL++LC G+I+ E+ RCFDWDGA GD ED+D E+D+LIGE T L+ S N + QLIN K+K+K+ Y NSG + + F+ ++FLDY+F G+ +N +VAVDMS +N S ++ +++ EYEVAI+AV+EILQEYD+D LFPAFGFGA++ K H YPL + N +CKG+ GVL AY+ L + S F+P+IR+V+ AK +Y+VLLILTNGTV+DWIETK++VIE S LP+SIIV+G+G G F++M+ LDQDFGLLKVG E+A RDNVQFV MR+FLR+AADGS +IRW+KVALAKEVLAELP Q++ Y+ +N
Sbjct: 1 MPHKPRIQIGISCRNIP-KLLKASYAKFSVSYGGYLHEKHVTETELVYNNLSPNYTTRLNLEYCFEEKQIITTEIFECEREDRENSVLLGYIQCTVGRVIHSGGELILPITWNEDIQVDRNTSTEVVVCIREDPFSKENIFIKMNGANLDKKDFFGKSDPYVIIYRRNERGKLQKCYRSEVIKNTLFPDWKPILICLDRLCGGNIDCELYFRCFDWDGAVGDSEDVDTEIDDLIGEFNTTVSRLLNSNENGIEFQLINMPKKKRKKCYQNSGLLTVKLYFAQSKFSFLDYIFGGLSINVVVAVDMSTHASMNSITNTPSQQI-ELSQSHTEYEVAIQAVMEILQEYDSDQLFPAFGFGAKVSSGGKLSHRYPL-VNVNNCYCKGMVGVLSAYRRCLTDLYSSGPILFSPIIREVSEAAKRSEAADNYYVLLILTNGTVDDWIETKKSVIETSFLPISIIVLGVGGGKFSEMEILDQDFGLLKVGQEQACRDNVQFVQMRRFLRLAADGSDSIRWSKVALAKEVLAELPSQILEYLDKN 535
BLAST of Copine-3 vs. TrEMBL
Match: A0A267G9Y0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017750g6 PE=4 SV=1) HSP 1 Score: 506.523 bits (1303), Expect = 6.272e-170 Identity = 267/547 (48.81%), Postives = 363/547 (66.36%), Query Frame = 1
Query: 13 SKVIISVGCRHLPLEVIRAYRV-TLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIF-----YQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGK-----IQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLK 1617
+KV+I V CR LP++ R++ V L G + KDT+ TE ++ T NP ++ L+ Y FEE+Q++ I + A+ K+ G C ++G +IH+GGS++ + S + I ++E + K N ++K++G LDKKDLFGKSDPY+I+ K++DKG+ +R YRTE+IKN L+PDWK I + +++LC GD+ +EI RC+DWDGAEGD ED D E DE IGE T + L ++ V +LIN +K KKK++Y NSG I I ADFS FLDYMFSG DL F VA+DM+ Q S+ + N+Y +A++AV+EI+Q+YD+D L PAFGFG + PPD++ HE+PLNGD N FC+G GVL AY+ L+ V+ F PVI+ V+ LA H DGS Y+VLLILT+GT++DW E KRAVIEAS LPVSIIVVGIGSG FT+M+ LDQD LL+ G +KA RD VQFV +RK+LR+AADGS +RW+KVALAK+VL ELP Q++ YM++ RLK
Sbjct: 33 AKVVIGVKCRDLPVD--RSFAVIALHSG--SYMTEKDTVTTETVDKTHNPTYSIPLITSYKFEERQMIELEIHCAMDDHSSRAASRKVIGSCTVSLGHLIHSGGSLDCQLCSSSPAVCT--------IHVEEYAGNKENMLLKLNGRGLDKKDLFGKSDPYMIIDKRNDKGRLVRAYRTEVIKNTLDPDWKPIKVSVDRLCGGDLRREIRFRCYDWDGAEGDHEDKDIEFDEFIGEFATTPKELFSNDGREVTFELINPRKAKKKKNYRNSGTVTAKTIPIDADFS-----FLDYMFSGTDLCFTVAIDMTASN-GSPSQPTSLH-YTDPFTPNQYTIAMQAVLEIIQDYDSDQLLPAFGFGCRAPPDYRVSHEWPLNGDSANPFCQGAAGVLEAYRHCLEEVRLSGPTHFAPVIKHVSRLALNHQDGSRYYVLLILTDGTIDDWTECKRAVIEASYLPVSIIVVGIGSGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRVAADGSDGVRWSKVALAKDVLQELPSQILEYMRRR--RLK 558
BLAST of Copine-3 vs. TrEMBL
Match: A0A267FGY6 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017750g2 PE=4 SV=1) HSP 1 Score: 503.827 bits (1296), Expect = 8.202e-169 Identity = 266/547 (48.63%), Postives = 362/547 (66.18%), Query Frame = 1
Query: 13 SKVIISVGCRHLPLEVIRAYRV-TLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIF-----YQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGK-----IQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLK 1617
+KV+I V CR LP++ R++ V L G + KDT+ TE ++ T NP ++ L+ Y FEE+Q++ I + A+ K+ G C ++G +IH+GGS++ + S + I ++E + K N ++K++G LDKKDLFGKSDPY+I+ K++DKG+ +R YRTE+IKN L+PDWK I + +++LC G+ +EI RC+DWDGAEGD ED D E DE IGE T + L ++ V +LIN +K KKK++Y NSG I I ADFS FLDYMFSG DL F VA+DM+ Q S+ + N+Y +A++AV+EI+Q+YD+D L PAFGFG + PPD++ HE+PLNGD N FC+G GVL AY+ L+ V+ F PVI+ V+ LA H DGS Y+VLLILT+GT++DW E KRAVIEAS LPVSIIVVGIGSG FT+M+ LDQD LL+ G +KA RD VQFV +RK+LR+AADGS +RW+KVALAK+VL ELP Q++ YM++ RLK
Sbjct: 33 AKVVIGVKCRDLPVD--RSFAVIALHSG--SYMTEKDTVTTETVDKTHNPTYSIPLITSYKFEERQMIELEIHCAMDDHSSRAASRKVIGSCTVSLGHLIHSGGSLDCQLCSSSPAVCT--------IHVEEYAGNKENMLLKLNGRGLDKKDLFGKSDPYMIIDKRNDKGRLVRAYRTEVIKNTLDPDWKPIKVSVDRLCGGEFRREIRFRCYDWDGAEGDHEDKDIEFDEFIGEFATTPKELFSNDGREVTFELINPRKAKKKKNYRNSGTVTAKTIPIDADFS-----FLDYMFSGTDLCFTVAIDMTASN-GSPSQPTSLH-YTDPFTPNQYTIAMQAVLEIIQDYDSDQLLPAFGFGCRAPPDYRVSHEWPLNGDSANPFCQGAAGVLEAYRHCLEEVRLSGPTHFAPVIKHVSRLALNHQDGSRYYVLLILTDGTIDDWTECKRAVIEASYLPVSIIVVGIGSGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRVAADGSDGVRWSKVALAKDVLQELPSQILEYMRRR--RLK 558
BLAST of Copine-3 vs. TrEMBL
Match: A0A4S2L3S0 (C2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009940 PE=4 SV=1) HSP 1 Score: 500.745 bits (1288), Expect = 9.598e-166 Identity = 256/541 (47.32%), Postives = 371/541 (68.58%), Query Frame = 1
Query: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEF-LETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKI----YGHCFSNMGRIIHNGGSIEVPIKI--ESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQN 1602
MP++ ++ I + C +LP ++ +Y V G H K +TE +T NP F ++L +EY FEE+QI+ + IF + +E +G C +GR+IH+GG +E+P+ E L + P+ + ++ED K N +KM GF+LDKKD FGKSDPYV +++++++GK + YR+E+IKN L PD++ I +CL++LC G+++ E+ RCFDWDGA GD E++D ELD+LIGE T L+ S+ + + +LIN K+K+K++Y +SG++++ + N++FLDY+F G +N ++ VD+S Q+ + R V + NEY VAI+AV+EILQEYD+D LFPA+GFG+++ K CH+YPL+GD N FCKG+ GVL AY+ + + + CF+P+IR V+ A+ + D +Y+VLLILTNGTV+DWIETK+AVIE S LP+SIIV+GIG G F DM+ LDQDFGLLKVG E+A RDNVQFV MR+FLR+AADGS +RW+KV LAKEVLAELP Q++ Y ++N
Sbjct: 1 MPSRPRIQIGISCTNLPTKLPGSY-AKFSVAHGGTLHEKHVTETEIQRQTRNPIFLTRLNLEYFFEERQIITSEIFQCEREDREDSQLLGFGQC--TVGRVIHSGGELELPLICNDEQKNLLDPGRPPSVFVCIREDPFSKENIYLKMQGFNLDKKDFFGKSDPYVTIYRRNERGKLQKAYRSEVIKNTLFPDFRPILVCLDRLCGGNVDCELCFRCFDWDGALGDSEEVDTELDDLIGEFTTTISELLRSDESGLEFKLINPPKKKRKKNYQDSGQLKVRLSLAQSNFSFLDYIFGGTSINVVIGVDLS--NHISSKQMPASRQIEVAQSCNEYSVAIQAVMEILQEYDSDQLFPAYGFGSRLSSGGKICHKYPLSGDENNYFCKGMAGVLEAYRRSFEALHLSGPICFSPIIRDVSDTARRNKDTENYYVLLILTNGTVDDWIETKKAVIETSFLPISIIVIGIGGGKFADMEILDQDFGLLKVGQEQACRDNVQFVQMRRFLRLAADGSDNLRWSKVGLAKEVLAELPSQILDYFERN 536
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149]) HSP 1 Score: 328.946 bits (842), Expect = 1.612e-104 Identity = 199/551 (36.12%), Postives = 308/551 (55.90%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CR+L P+ V+ V ++ +TE ++ T NPDF + +++Y FEEKQ L ++ DS S + G F +G I+ GS P L + K T I+ +E +++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+S I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y+NSG + +++ FS+++ +TFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ +N +C G++G+L AY +LKTV+ F PV+ V A DGS YFVLLI+T+G + D +TK A++ + LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQ ++YMK ++
Sbjct: 28 TKVEITVSCRNLLDKDTFSKSDPMCVLYTQGVET-------KQWREFGRTEVIDNTLNPDFVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIV---GS---PASRLDKPLGGIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLS-FSVESEFTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQFISYMKSRGIK 549
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149]) HSP 1 Score: 326.635 bits (836), Expect = 1.432e-103 Identity = 199/556 (35.79%), Postives = 308/556 (55.40%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQE---------KIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CR+L P+ V+ V ++ +TE ++ T NPDF + +++Y FEEKQ L ++ DS S + G F +G I+ GS P L + K T I+ +E +++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+S I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y+NSG + +++ FS+++ +TFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ +N +C G++G+L AY +LKTV+ F PV+ V A DGS YFVLLI+T+G + D +TK A++ + LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQ ++YMK ++
Sbjct: 28 TKVEITVSCRNLLDKDTFSKSDPMCVLYTQGVET-------KQWREFGRTEVIDNTLNPDFVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHPSECNDFLGQMFCTLGEIV---GS---PASRLDKPLGGIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWD--------RDGSHD-FIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLS-FSVESEFTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQFISYMKSRGIK 554
BLAST of Copine-3 vs. Ensembl Cavefish
Match: CPNE9 (copine family member 9 [Source:HGNC Symbol;Acc:HGNC:24336]) HSP 1 Score: 310.071 bits (793), Expect = 1.780e-97 Identity = 185/502 (36.85%), Postives = 288/502 (57.37%), Query Frame = 1
Query: 127 KTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDS----ASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVT-RQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
+TE +E T NPDF + V+++ FEEKQ L ++ D+ S+ G F +G II + GS ++E L+ + K I +E S ++ M++ LDKKD FGKSDP+++ ++ ++ G + ++TE+IKN LNP W+ I + LC+GD ++ + FDWD D D IGE + + L ++ + +++N KK+ KK+ Y+NSG + +++ YTF+D++ G L+ + P L + + L ++ Q N Y +A+KAV EI+Q+YD+D LFPA+GFGA++PPD K H +PLNG+ ++ C ++GVL AY +L+TV+ F PVI QV A++ DGS YFVLL++T+G + D ++TK AV+ AS+LP+SII+VG+G F M+ LD D + A RD VQFVP R ++ D S + LAK+VLAE+PDQL+++MK +
Sbjct: 45 RTEVIENTLNPDFVRKFVLDFFFEEKQNLRFDVYNVDTRSSNISKHDFLGQTFCTLGEIIGSTGS-----RMERT-LSGIPGKKCGNIIFTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVFDWD--------RDGSHD-FIGEFTTSYRELSRGQSQFNVYEVLNPKKKGKKKKYVNSGTVTLLSFKVESEYTFVDFIRGGYSLDHTKIKCVPNPSLISGNPAQPTSLHYMSPYQMNTYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPDGKISHVFPLNGNSEDPNCVAIEGVLEAYFQSLRTVQLYGPTNFAPVINQVARSAQDVTDGSQYFVLLMITDGVISDMVQTKEAVVNASALPMSIIIVGVGPAEFDAMEELDGDDVRVSSRGRFAERDIVQFVPFRDYI----DRSGNQVLSMARLAKDVLAEIPDQLLSFMKSKGI 527
BLAST of Copine-3 vs. Ensembl Cavefish
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 309.686 bits (792), Expect = 2.880e-97 Identity = 192/551 (34.85%), Postives = 301/551 (54.63%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CR+L P+ V+ + G ++ +TE ++ T NP+F + +++Y FEE+Q L ++ DS S + G +G I+ + GS +E P L + K T I+K +E + + + MM+ G LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W++ I + LC+GD + + IGE + + L ++ + ++IN KK+ KK+ Y+NSG + +++ + TFLDY+ G +NF VA+D + N Q S+ + Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+ LNG+ QN +C G+DGV+ AY +LK+V+ F+PVI V A DGS YFVLLI+T+G + D +TK +++ AS LP+SII+VG+G F M LD D + A RD VQFVP R ++ D + + LAK+VLAE+PDQ ++YMK ++
Sbjct: 30 TKVEITVSCRNLLDRDTFSKSDPICVLYTQGI-------GNKEWREFGRTEVIDNTLNPEFVRKFILDYFFEERQNLRFDLYDVDSKSSNLSKHDFLGQAQCTLGEIVGSMGSRLEKP-------LGGIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYDSH-----------------------DFIGEFSTSYRELSRGQSQFNVYEVINPKKKGKKKKYLNSGTVTLLSFLVDIDVTFLDYIKGGTQINFTVAIDFTASNGN-PAQPTSLHYMS-PYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCNGIDGVMEAYYQSLKSVQLYGPTNFSPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASCLPMSIIIVGVGPAEFDAMVELDGDEVRISSRGRYAERDIVQFVPFRDYI----DRTGNHILSMARLAKDVLAEIPDQFLSYMKTRGIK 537
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne1 (copine-3-like [Source:NCBI gene;Acc:103034615]) HSP 1 Score: 305.449 bits (781), Expect = 3.630e-95 Identity = 197/545 (36.15%), Postives = 306/545 (56.15%), Query Frame = 1
Query: 16 KVIISVGCRHLPLEVIRAYRVTLDVGFE--GFSHHKDTMKTEFLET-SNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTF--IIKLKEDSVKKNN-FMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSL---AKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
KV +++ C++L + + + L V + G + +TE ++ +P+F+ +L V+Y FE+ Q L ++ D+ S + G +G+I+ K +N L K KP I + D VK N ++++ +LDKKD+FGKSDP++ FK++D G W +RTE+IKNNLNP WK + + C+ D NK + C+D D ED ++L IGE T +L+E+ + V I+ +KQKKK+SY NSG ++I YTFLDY+ G +NF V +D + + ES+ + +N+Y AI +V +++++YD D LFPAFGFGAQ+PPDFK HE+ LN + + FC+G++G+++AY+ AL V+ F+P+I V + A + + + YFVLLI+T+G + D +TK+A++ +S LP+SII+VG+G F M+ LD D G+LK E SRD VQFVP + F + ALA+ VLAE+P QLV+Y K ++
Sbjct: 70 KVELTISCKNLLDKDVGSKSDPLCVLLQSTGNDQWTEVDRTERVKNCQDPEFSKRLCVDYHFEKVQKLKLGVYDIDNKSVDLKDDDYLGGFECTLGQIVST--------KKVTNPLELKKGKPAGKGTITIVADEVKDNRAIVLEVEARNLDKKDMFGKSDPFLEFFKQADDGSWTLVHRTEVIKNNLNPSWKKFTVSVGTFCNADFNKPLKVACYDKD------EDTSSDL---IGEFSCTTANLLEARDQGVEFDCIHPEKQKKKKSYKNSGVVRIKNCKIEAQYTFLDYVMGGCQINFTVGIDFTGSNGDPRSP-ESLHYLS-PDGTNQYLNAIWSVGQVIKDYDTDKLFPAFGFGAQVPPDFKVSHEFALNFNPNSPFCQGIEGIVQAYRAALPQVRLYGPTNFSPIINHVARIAAGAAQQSNAAQYFVLLIITDGEITDLDQTKQAIVNSSKLPMSIIIVGVGEADFKAMEVLDGDNGVLKAPSGEPVSRDIVQFVPFKSFASAPRE----------ALAQTVLAEVPGQLVSYFKMRNI 585
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 306.22 bits (783), Expect = 9.759e-97 Identity = 197/507 (38.86%), Postives = 292/507 (57.59%), Query Frame = 1
Query: 118 DTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTF--IIKLKEDSVKKNNFM-MKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQL--INHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKE---HCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
+ +TE ++ T PDF+ +LV+EY FEE Q L +F +D+ S K+ H F +G I G I V + + L ++P I + + + N + + M+G LDK DLFGKSDPY+ ++K+S G W+ +RTE+++N L+P WK + L LC+GD+ K I A C+DWD G P +LIGE L E+ + +++ IN+KK++KK+SY NSG I + ++YTFLDY+F G L+F V +D + N D S+ + T N+Y AI AV +I+Q+YD D LFPA GFGAQ+PPD K H++ LN + N FC G++G++ AY L+ ++ F+P+I V S A S Y+VLLI+T+G + D T+ A+++AS LP+S+I+VG+G+ F M+ LD D +L E A+RD VQFVP R+F + D + K LAK VLAELP Q+V Y +Q ++
Sbjct: 55 EVARTETIKNTLCPDFSRKLVMEYRFEEVQKLKFALFDEDAPSA-KLVDHDF--LGEITSTLGQI-VSHRTLTRPLLMQDDRPAGRGTITISAEEITDNRIITLSMAGRKLDKMDLFGKSDPYLEIYKQSPDGTWMLVHRTEVVRNTLDPTWKPFTLHLQVLCNGDLEKNINAVCYDWD-RHGSP--------DLIGEFYANIIRLKEATGSMEVVEFECINNKKKQKKKSYKNSGIIICKSCKISRDYTFLDYIFGGCQLHFTVGIDFTASNGNPRDA-SSLHYISPTGM-NDYLAAIWAVGQIIQDYDTDKLFPALGFGAQLPPDCKVHHDFALNFNPSNPFCTGIEGIVAAYHFCLQNIRLYGPTNFSPIINHVASFAHTASGSASASEYYVLLIITDGVISDMEATREAIVKASRLPMSVIIVGVGNADFEAMEVLDSDDRVLTAPSGEAATRDIVQFVPFRQF--RSVDRLLINKAAKEELAKSVLAELPGQVVQYFRQRNL 544
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007777.1 (pep scaffold:Pmarinus_7.0:GL477373:3581:22444:1 gene:ENSPMAG00000006999.1 transcript:ENSPMAT00000007777.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 251.906 bits (642), Expect = 3.249e-76 Identity = 172/506 (33.99%), Postives = 275/506 (54.35%), Query Frame = 1
Query: 13 SKVIISVGCRHLPLEVIRAYRVTLDVGF-EGFSHHKDTMKTEFLETSN-PDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFM-MKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRL--FNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSL---AKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKF 1491
SKV ++V C+ L + + + L V E + +TE ++ P F+ +L ++Y FE+ Q L ++ D+ + + G N+ +++ + + P+ L N K I + D +K N + +++ +LDKKD+FGKSDPY+ FK +D G W +RTE+IKNNLNP W+ I L LC+GD+ +++ C+D+D ++G +LIGE ++L ++E V +I+ +K+KKK++Y SG + + + + Y+FLDY+ G +NF V + L + D I I L ++ A+ + I + D LFPAFGFGAQIPP+++ HE+PLN + N +C GV G++ Y+ L V+ F+P+I V A + + YFVLLI+T+G + D ET+ AV++AS LP+S+I+VG+G+ F+ M+ LD D G+LK E A+RD VQFVP R F
Sbjct: 38 SKVELTVSCKDLLDKDVGSKSDPLCVVLIEAGGTWSEVDRTEQIQNCQEPAFSKRLQIDYCFEQVQKLRFGVYDIDNKTYDLTDDDFLGQLECNLAQVV-SSKKMTRPLL-----LKNGKPAGKGQITIVADEIKDNRVLALQVDARNLDKKDMFGKSDPYLEFFKMADDGTWQMVHRTEVIKNNLNPTWRPFSIPLQALCNGDLERDVRVVCYDYD-SDGS--------HDLIGEFKTNVKNLQQAEKGQVEFAVIHPEKKKKKKNYKGSGLVIVKSCRTEVEYSFLDYIMGGCQINFTVRSALR-SCLTLGD-IHRINLLTLHIPWPLLPLNNALSSFNGIKSHHLQDKLFPAFGFGAQIPPNWQVSHEFPLNFNPANPYCNGVQGIVDMYKVCLPQVRLYGPTNFSPIINHVARFAAAALQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGNADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDF 526
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000748.1 (pep scaffold:Pmarinus_7.0:GL477446:179420:193439:1 gene:ENSPMAG00000000673.1 transcript:ENSPMAT00000000748.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 239.965 bits (611), Expect = 2.041e-73 Identity = 148/398 (37.19%), Postives = 219/398 (55.03%), Query Frame = 1
Query: 445 KDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWD-GAEGDPEDMDAELDELIGESVFTCQHLIESE-NNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRL--FNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKE---HCDGSH-YFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+D FGKSDP++ L+K++ GKW YRTE+ KN LNP WK+I + L LCDG+I K I C DW+ +P IGE + T L +++ NNTV+ L+ K +Y NSG++ ++ + YTFLDY+ G L F +A+D + Q++S+ FN +N+Y + I+AV LQ YD D FPA+GFGAQ+P + K ++PL + N C GV +++AY++ L VK A PVI +V + AK +H Y +L I+T+G V+D T+ A+++AS LP+SI++VG+GS F D+ LD D +L E A RD VQFVP F R + ++V+ E+P Q+ Y Q D++
Sbjct: 1 QDWFGKSDPFLELYKQTSIGKWKLVYRTEVHKNTLNPRWKNIVLNLQSLCDGNIAKPIKVVCADWNRNGRSNP----------IGECIVTVMQLNQAKLNNTVMFDLV-LPGNVKNSNYKNSGQLVVVLCTICRQYTFLDYIRGGCKLQFSMAIDFTASN-KPPSQLDSLHHTGFN---DANQYLMVIRAVGGTLQYYDADKQFPAYGFGAQLPSEEKVSQDFPLTLNANNPNCDGVQALIKAYKSCLTKVKLSEPANLAPVINRVATAAKRIKFQSKLAHEYHILFIITDGEVKDMPATREAIVQASKLPLSIVLVGVGSNDFRDLVELDSDDAILTAPSGENAFRDIVQFVPYLDFARDPVE----------KFLEQVMEEIPHQVEQYFHQMDLQ 373
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 176.792 bits (447), Expect = 2.021e-51 Identity = 98/213 (46.01%), Postives = 136/213 (63.85%), Query Frame = 1
Query: 973 SNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQV---NSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKV-GNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQ 1599
+NEY A+ AV +++Q+YD D FPA GFGAQ+PP+++ HE+ LN + N FC GV+G+++AY L V+ F+P+I V + A + + YFVLLI+T+G + D ET+ AV++AS LP+S+I+VG+GS F+ M+ LD D G+LK E A+RD VQFVP R F R A K ALAK VLAE+P Q+V Y KQ
Sbjct: 26 TNEYLAAVWAVGQVIQDYDADKQFPALGFGAQLPPEWEVSHEFALNFNPLNPFCTGVEGIVQAYMACLPQVRLYGPTNFSPIINHVARFAAAAAQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGSADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDF-RNAP---------KEALAKAVLAEVPGQVVTYFKQ 228
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 111.309 bits (277), Expect = 9.689e-28 Identity = 80/261 (30.65%), Postives = 132/261 (50.57%), Query Frame = 1
Query: 13 SKVIISVGCRHLPLEVIRAYRVTLDVGFE--GFSHHKDTMKTEFLETS-NPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTF--IIKLKEDSVKKNNFM-MKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQ 777
+KV +SV C +L + I + L V + G + + +TE ++ NP F + ++Y FEE Q L I+ DS S+ ++ H F +G + G + V K S L +P II++ + +K N + + G LDKKD FGKSDPY+ FKK D G W+ +RTE++ N LNP W+ + + LC GD+++ + C+D+D G + IGE + ++E+++ + +N KK+
Sbjct: 6 TKVEMSVSCTNLLDKDITSKSDPLCVLYMECGPGNWMELGRTESMKNDLNPVFAHKFQIDYHFEEVQKLRFAIYDLDSPSK-RLQDHDF--LGDLTLTLGQV-VSSKKLSRALVLKDGRPAGKGIIQVLAEEMKDNRHLQLLFEGIKLDKKDFFGKSDPYLEFFKKGDDGSWVLVHRTEVVLNTLNPSWRPFTLAVQSLCGGDLDRSVRVTCYDYDSDGG---------HDFIGEFQTSVTQMLEAQSGKQVRTCMNVKKK 253
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO44352 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW53]) HSP 1 Score: 301.212 bits (770), Expect = 1.030e-94 Identity = 202/546 (37.00%), Postives = 300/546 (54.95%), Query Frame = 1
Query: 13 SKVIISVGCRHLPLEVIRAYRVTLDVGFE---GFSHHKDTMKTEFLETS-NPDFTSQLVVEYVFEEKQILAATIFYQDSASQE----KIYGHCFSNMGRII-HNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKE---HCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFL-RMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
++V ISV CR+L + + + V F G ++ +TE + + NPDF + + Y FEE Q L ++ D S G +G I+ NGG +E + E E++ K+ T ++ G LDKKD FGKSDP+++ ++ ++ + +RTE++KN LNP WK + LC+GDI++ I C+DWD D D LIG T + L + N T +L N KKQ KK+SY NSG I ++ Q TFLD++ G ++FIVA+D + N ++ S+ N + N+Y A+ +V I Q+YD+D LFPAFGFGA++PP+++ HE+ LNG+ QN FC+ V+GV+ +Y +++ V+ F+P+IR+ +LAKE G YFVLLILT+G + D +TK A+++A+SLPVSII+VG+G F M+ LD D L A RD VQFVP R +L + D + R LAK+VL ELPDQL YMK+ +++
Sbjct: 12 TQVEISVSCRNLADMDVFSKSDPMVVMFTQGMGTKEWREFGRTEVIMNNLNPDFVKKFTIHYFFEEIQKLRFQVYDIDKKSSRLQDHDFIGEIECTLGSIVGENGGQLEKALLCE--EVSQCKDVAT----------------LQFRGHKLDKKDFFGKSDPFLVFYRCNEDNSFTAVHRTEVVKNTLNPTWKPFSVPARALCNGDIDRSIRIECYDWD--------RDGSHD-LIGIFSTTLRELTSNPNLT--FELKNPKKQAKKKSYKNSGTIILLQSKLEQQPTFLDFIKGGTQISFIVAIDFTASNGNPQNS-NSLHFLN-PYEPNQYVKALTSVGAICQDYDSDKLFPAFGFGARLPPNWEVSHEFALNGNPQNPFCERVEGVISSYFHSIQRVQLYGPTNFSPIIRRTVALAKESERQKPGEEYFVLLILTDGIISDMEQTKAAIVDAASLPVSIIIVGVGGADFEAMEELDGDEVRLSSRGRLAERDIVQFVPFRDYLDKCYGDITSGAR-----LAKDVLEELPDQLTDYMKKRNIK 521
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO39500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X6]) HSP 1 Score: 290.812 bits (743), Expect = 1.191e-90 Identity = 184/495 (37.17%), Postives = 270/495 (54.55%), Query Frame = 1
Query: 151 NPDFTSQLVVEYVFEEKQILAATIFYQDSASQE----KIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMS--GFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHC-DGS--HYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
NPDF+ + V+Y FE Q L ++F D+A+++ G +G+I+ K + +K + I + + +K N ++K++ +LD KD GKSDP++ L K G + +RTE+IKNNLNP WK + + LC D + I C D+DG D D LIG + + + L+E + + LIN KK+ KK+ Y+NSG + I + + TFLDY+ G +NF V VD + N +S+ N + NEY A+ +V E+ Q+YD+D LFPAFGFGA+IPP+F+ HE+ LN + N +C+G+ GV+ AYQ ++ V+ +P+I V S A+ DG+ YFVLL++T+G + D TK A++ AS LP+S+I+VG+GS FTDM LD D G L+ G+E+A RD VQFVP R F KT LAK VLAE+P Q Y +
Sbjct: 55 NPDFSKAISVDYYFELVQKLKFSVFDVDNATKQLDDDDFLGSIECTLGQIVS---------KKSFTKHLEIKGRQVGTITIYAEEMKGANEIVKLTFRATNLDNKDFMGKSDPFLELLKLKPDGGTLLVHRTEVIKNNLNPTWKVFSLPIQSLCSADYDATIRIDCHDYDG--------DGSHD-LIGIANTSLRQLLELRQSGSGLDLINPKKKAKKKKYVNSGVLYISGCEVIHHNTFLDYVMGGCQINFTVGVDFTASNGN-PSTPQSLHYIN-PYEPNEYVNALVSVGEVCQDYDSDKLFPAFGFGAKIPPNFQVSHEFALNFNPSNPYCEGIPGVVAAYQACIRQVQLYGPTNASPIINHVASFAQRAAQDGTAGAYFVLLLITDGVLSDMEATKLAIVRASRLPMSLIIVGVGSADFTDMNELDADEGTLRAGHERAERDIVQFVPFRDF--------KT--QPPAMLAKHVLAEVPKQAQEYFNSRGI 519
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO45927 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRD6]) HSP 1 Score: 269.626 bits (688), Expect = 1.227e-82 Identity = 189/553 (34.18%), Postives = 284/553 (51.36%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQ--LINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGS----HYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDV 1608
S+V +++ C++L PL V+ R ++ ++ +TE LE T NP+F++ +VV+Y FEE Q L ++ DSAS G +G+++ + T+ LK S K M D FGKSDPY+ + + G ++ +RTE++ NNLNP WK I I +LC+GD ++ + C+DWD D +LIG T + L + +Q IN KK+KKK++Y NSG I + + ++ +FLD++ G +NF V +D + N S+ N NEY A+ AV EI+Q+YD+D LFPAFGFGA++PP+ H++ LN + N FC G+ G++ AYQ ++ V P+I V A+ +Y++LLILT+G + D +TKRA+++AS LP+SII+VG+GS F M+ LD D GLL+ A RD VQFVP RKF +++ ALAKEVLAE+P Q+ Y K ++
Sbjct: 25 SRVQLNISCKNLIDKDVMSKSDPLVVVMMLR---------HNNWEEVGRTERLENTLNPNFSTTIVVDYFFEELQKLKFMVYDIDSASGSLKNADFLGEMQCTLGQLVSSA---------------------TYTHNLKIPSGKPAGNM----------TDFFGKSDPYLEFSRAKEDGSFVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWD---------DDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPT-SLHYIN-PYAPNEYCQALTAVGEIIQDYDSDKLFPAFGFGAKVPPNNMVSHQFALNFNHTNPFCAGLQGLIEAYQQCVRQVTLYGPTNIAPIISNVAMYAQAAAQQPYASLNYYILLILTDGVISDMDQTKRAIVQASGLPMSIIIVGVGSADFEMMEELDADDGLLRSEGSTAQRDIVQFVPFRKFKNLSS----------AALAKEVLAEVPGQVTGYYKMRNI 516
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO49902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF64]) HSP 1 Score: 149.443 bits (376), Expect = 4.146e-39 Identity = 93/336 (27.68%), Postives = 163/336 (48.51%), Query Frame = 1
Query: 403 NNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTV-IIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHC--DGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDM 1401
N ++SG +L+K+ L K D + L + G + YR+EI+ L+P W I L KLC+ ++ +E + C+ + + + LI + HLI N ++ ++QL+ +K +K R +G ++I ++++ +DY+ G D+ A+D ++ + + S+ + Q NEY A++A+ +L YD D P F FGA+ C + LNGD ++ ++ Y +L T+K PVI+++ A D HY V +++ +G D +TK +I+ S LP+SI+VVG+G FT M
Sbjct: 133 TNVRFQISGVNLEKRSLLSKWDVFFELERLLPGGFYHPVYRSEIVARTLDPRWSPFDIYLQKLCNEEVTREAVISCWHYSSSGA---------NTLIASARCPVGHLI---NRSIKVLQLVKPQKTQKARRAGTAGSLRIDHCHVDKHFSLVDYIRGGCDVTIACAIDFTLSNGDPSCR-SSLHTLSCLYQ-NEYIGALRALGPVLMHYDEDKQIPTFAFGAKSKHGIPYC--FALNGDESEPEISSIETLIDTYTRSLTTIKLGGPTYLVPVIKRLADYATRELSQDSQHYLVAMVIMDGVANDLDDTKEQIIQVSGLPLSIVVVGVGPADFTAM 452
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO26801 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TB16]) HSP 1 Score: 99.3673 bits (246), Expect = 4.492e-23 Identity = 72/202 (35.64%), Postives = 108/202 (53.47%), Query Frame = 1
Query: 430 FDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQ--LINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYD 1029
+D KD FGKSDPY+ + + G ++ +RTE++ NNLNP WK I I +LC+GD ++ + C+DWD D +LIG T + L + +Q IN KK+KKK++Y NSG I + + ++ +FLD++ G +NF V +D + N S+ N NEY A+ AV EI+Q+YD
Sbjct: 101 YDRVLKDFFGKSDPYLEFSRAKEDGSFVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWD---------DDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPT-SLHYIN-PYAPNEYCQALTAVGEIIQDYD 291
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5b (copine-8 [Source:NCBI gene;Acc:101170754]) HSP 1 Score: 334.339 bits (856), Expect = 7.285e-106 Identity = 202/552 (36.59%), Postives = 311/552 (56.34%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CRHL P+ V+ V ++ +TE ++ T NPDF + +++Y FEEKQ L ++ DS S + G F +G I+ + S +E P L + K T I+ +E S +++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ I +DWD D D IG+ + + L ++ + ++IN KK+ KK+ Y+NSG + +++ FS+++ +TFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ +N +C G++G+L AY +LKTV+ F PV+ V A DGS YFVLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQ ++YMK V+
Sbjct: 86 TKVEITVSCRHLLDKDTFSKSDPMCVLYTQGVET-------KQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQVFCTLGEIVGSPASRLEKP-------LGGIPGKKCGTIILSAEELSNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGDFTTSYRELARGQSQFNVYEVINTKKKMKKKKYVNSGTVTLLS-FSVESEFTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNLENPYCNGIEGILEAYHESLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRVSSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQFISYMKSRGVK 607
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5b (copine-8 [Source:NCBI gene;Acc:101170754]) HSP 1 Score: 328.946 bits (842), Expect = 4.793e-105 Identity = 191/504 (37.90%), Postives = 294/504 (58.33%), Query Frame = 1
Query: 127 KTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+TE ++ T NPDF + +++Y FEEKQ L ++ DS S + G F +G I+ + S +E P L + K T I+ +E S +++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ I +DWD D D IG+ + + L ++ + ++IN KK+ KK+ Y+NSG + +++ FS+++ +TFLDY+ G +NF VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ +N +C G++G+L AY +LKTV+ F PV+ V A DGS YFVLLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQ ++YMK V+
Sbjct: 19 RTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQVFCTLGEIVGSPASRLEKP-------LGGIPGKKCGTIILSAEELSNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGDFTTSYRELARGQSQFNVYEVINTKKKMKKKKYVNSGTVTLLS-FSVESEFTFLDYIKGGTQINFTVAIDFTASNGN-PSQSTSLHYMN-PYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNLENPYCNGIEGILEAYHESLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRVSSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQFISYMKSRGVK 499
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne8 (copine-8 [Source:NCBI gene;Acc:101173626]) HSP 1 Score: 328.946 bits (842), Expect = 1.519e-104 Identity = 187/503 (37.18%), Postives = 294/503 (58.45%), Query Frame = 1
Query: 127 KTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIF----YQDSASQEKIYGHCFSNMGRIIHNGGS-IEVP-IKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLIN-HKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+TE ++ T NPDF + +++Y FEE+Q L ++ D+ S+ G F +G I+ + GS +E P I I K T I++ +E S + + M++ G LDKKD FGKSDP+++ ++ ++ G + ++TE++KN L+P W++ I + LC+GD ++ I +DWD G + IGE + + + S++ I +++N KK KKK+ Y+NSG + +++ +FLDY+ G +NF VA+D + N Q S+ + Q N+Y +A++AV EI+Q+YD+D LFPA GFGA++PPD + HE+PLNG+ QN +C G+DGVL AY +LK+V+ F+PVI V A DGS YF+LLI+++G + D +TK +++ A+SLP+SII+VG+G F +M LD D + A RD VQFVP R ++ D + LAKEVLAE+PDQ ++YM+ ++
Sbjct: 60 RTEVIDNTLNPDFVRKFILDYFFEERQNLRFDLYDLDCKSDNLSKHDFLGQAFCTLGEIVGSLGSRLEKPLIGIPG------KKCGTIIVRAEELSNCRESVMLQFCGNKLDKKDFFGKSDPFLVFYRSNEDGSYTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRSIKVEVYDWDRDGGH---------DFIGEFSTSYREMSRSQSQFHIYEVLNPKKKGKKKKKYLNSGTVTLLSCLVDTELSFLDYIRGGTQINFTVAIDFTASNGN-PSQPTSLHYMS-PYQLNDYAMALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPQNPYCNGIDGVLEAYYQSLKSVRLYGPTHFSPVINHVARYASAVTDGSQYFILLIISDGVITDMAQTKESIVNAASLPMSIIIVGVGPAEFDEMIELDGDEERISSQGRYAERDIVQFVPFRDYI----DRRGNHILSMARLAKEVLAEIPDQFLSYMRTRGIK 541
BLAST of Copine-3 vs. Ensembl Medaka
Match: CPNE8 (copine 8 [Source:NCBI gene;Acc:101158741]) HSP 1 Score: 325.865 bits (834), Expect = 2.516e-103 Identity = 199/551 (36.12%), Postives = 306/551 (55.54%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVR 1611
+KV I+V CR+L P+ V+ + G ++ +TE ++ T NPDF + +++Y FEE+Q L ++ DS S + G + +G I+ + GS +E P L + K T I+K +E + + + MM+ G LDKKD FGKSDP++I ++ ++ G + ++TE++KN LNP W++ I + LC+GD ++ I +DWD D D IGE + + L ++ + +++N KK+ KK+ Y+NSG + +++ TFLDY+ G +NF VA+D + N Q S+ + Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+ LNG+ QN +C G+DGV+ AY LK+V+ F PVI V A DGS YFVLLI+T+G + D TK A++ AS LP+SI++VG+G F M LD D + A RD VQFVP R + M G+ + + LAK+VLAE+PDQ ++YM+ ++
Sbjct: 24 TKVEITVSCRNLLDMDTFSKSDPICVLYTQAI-------GNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERQNLRLDLYDVDSKSANLSKHDFLGQAYCTLGEIVGSLGSRLEKP-------LGGIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLIFYRSNEDGTFTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFSTSYRELSRGQSQFNVYEVVNPKKKGKKKKYLNSGTVTLLSFLVDIEVTFLDYIKGGTQINFTVAIDFTASNGN-PAQPTSLHYMS-PYQLNTYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCDGIDGVMEAYYQTLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVITDMALTKEAIVNASGLPMSILIVGVGPAEFDAMVELDGDEVRISSRGRLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQFLSYMRTRGIK 545
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5a (copine-5 [Source:NCBI gene;Acc:101166794]) HSP 1 Score: 325.479 bits (833), Expect = 4.039e-103 Identity = 202/572 (35.31%), Postives = 318/572 (55.59%), Query Frame = 1
Query: 13 SKVIISVGCRHL----------PLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLE-TSNPDFTSQLVVEYVFEEKQILAATIFYQDSAS----QEKIYGHCFSNMGRIIHNGGS-IEVPIKIESNELNNMKNKP--TFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQN-YTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPVHKQYDNFKSPK 1671
+KV I+V CR+L P+ V+ G E ++ +TE ++ T NPDF + +++Y FEEKQ L ++ DS S + G + +G I+ + S +E P L + K T I+ +E ++ M+ LDKKD FGKSDP+++ ++ ++ G + ++TE++KN LNP W+ I + LC+GD ++ I +DWD D D IGE + + L ++ + + +++N KK+ KK+ YINSG + +++ FS+++ +TFLDY+ G ++F VA+D + N Q S+ N Q N Y +A+KAV EI+Q+YD+D +FPA GFGA++PPD + HE+PLNG+ +N +C G++G+L AY +LK V+ F PV+ V A DGS YF+LLI+T+G + D +TK A++ A+ LP+SII+VG+G F M LD D + + A RD VQFVP R + M G+ + + LAK+VLAE+PDQL++YMK ++ +PV Y +P+
Sbjct: 28 TKVEITVSCRNLLDRDTFSKSDPMVVLYTQ------GVES-KQWREFGRTEVIKNTLNPDFVRKYILDYFFEEKQNLRFDVYDIDSKSPDLGKHDFLGQVYCTLGEIVGSPASRLEKP-------LGGIPGKTCGTIILSAEELGNCRDYATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPMWQPFSIPVRALCNGDYDRTIKVEVYDWD--------RDGSHD-FIGEFSTSYKELCRGQSESNVYEVVNAKKKLKKKRYINSGTVSLLS-FSVESEHTFLDYIKGGTQIHFTVAIDFTASNGN-PSQSTSLHYMN-PYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVENPYCNGMEGILEAYHQSLKLVQLYGPTNFAPVVNHVARYAAAVEDGSQYFILLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDY--MDRTGNHVLSMAR--LAKDVLAEIPDQLISYMKSRAIK-----PNPVPPPYSTCNNPE 564
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000043402.1 (SMESG000043402.1) HSP 1 Score: 1075.08 bits (2779), Expect = 0.000e+0 Identity = 536/604 (88.74%), Postives = 539/604 (89.24%), Query Frame = 1
Query: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEY-PLNGDF------------------------------------------QNAFC--KGVDG------------VLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPVH 1641
MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEY + G F FC K ++G VLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPV
Sbjct: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYLCIIGSFIRNTDLHVDIRPTFTTAAHLKSQLRKSQTSDLYRKDCLCHSSTKCFCFSKNINGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPVQ 604 HSP 2 Score: 167.933 bits (424), Expect = 6.271e-44 Identity = 81/83 (97.59%), Postives = 83/83 (100.00%), Query Frame = 2
Query: 1643 NSMTISNLRKNYSIKSYVVASPHMSISDRILDLMSKAGEINRIPCHILISFPIEAYERSQLILFIKTMTGRIKFYQIKENNLR 1891
NSMTISNLRKNYSIKSYVVASPHMSISDRILDLMSKAGEI+RIPCHILISFPIEAYERSQL+LFIKTMTGRIKFYQIKENNLR
Sbjct: 605 NSMTISNLRKNYSIKSYVVASPHMSISDRILDLMSKAGEISRIPCHILISFPIEAYERSQLMLFIKTMTGRIKFYQIKENNLR 687
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000043402.1 (SMESG000043402.1) HSP 1 Score: 760.37 bits (1962), Expect = 0.000e+0 Identity = 367/367 (100.00%), Postives = 367/367 (100.00%), Query Frame = 1
Query: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEY 1101
MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEY
Sbjct: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEY 367
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000029196.1 (SMESG000029196.1) HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0 Identity = 320/609 (52.55%), Postives = 412/609 (67.65%), Query Frame = 1
Query: 10 KSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESN--ELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPVHKQYDNFK-SPKELQHQKLRRCVTAHVNIRPNSGSDVEGRRDKQDSMSHSDFFSNRSLRKKSTD 1827
K KVI+ +GC +LP + +Y V G+ H KD MKTE NP F QL ++Y FEEKQ + IF S+ G S +GR+IH+GG + + I I+ + NN + P I ++EDS K N +KM GF+LDKKDLFGKSDPYVI++KK+++GK ++TYR+EIIKN LNPDW+SI + + KLC+ ++ EI +CFDWDGA+GDPEDMD E DE+IGE + + +LIN +K+KKK+ Y NSG + + + ++ +F+DYMF G DLNFIVA+D++ +I D S F SNEY +AI+AV+EILQEYDND LFPAFGFGA++ PDFK CHEYPL GDF N FC GV+GV+ AY L+ +K F PVIRQV +LAK++CDGSHYFVLLILT+GTV+DWIETK+AVIEAS LP+SIIVVG+G G F DMKTLDQDFGLLKVGNE+A RDNVQFVPMRKFLR AADGS ++W+KVALAKEVLAELP+QL+ YM +++++ + S + DN K + KE QKLRRC TA+ + N R+ D ++ F R RK S D
Sbjct: 3 KPKVIVGIGCLNLP-DTFLSYYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLSKDSKISKIGCAESTIGRVIHSGGELFLQINIDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRKKKKKKGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHD--PSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIVVGVGGGKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSN-------RQGSTDGLNGRGF---RGTRKCSVD 598
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000007275.1 (SMESG000007275.1) HSP 1 Score: 589.726 bits (1519), Expect = 0.000e+0 Identity = 304/579 (52.50%), Postives = 411/579 (70.98%), Query Frame = 1
Query: 1 MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETS-NPDFTSQLVVEYVFEEKQILAAT---IFYQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKNKPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESENNTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPVHKQYDNFKSPKEL-----QHQKLRRCVTA 1710
M KSKV+IS+ CR+LP E Y TL V G+ H KDT+ TE ++ S + DF +L +EY+FEEKQI+ I++ +SA + C ++GRIIH+GG + + ++ + I K+ ED+ K+N +KM G+ LDKKD+FGKSDPYVI+++++DKGK IRTYR+E++KN LNPDWK++ L +LC D++ E++ +CFDWDGA GDPEDMD E DELIGE T ++L+ + +L+N +K+KKK++Y +SG I I ++ + +FLDYMF G DLNFIVA+D++ ++ED S+ +V +NEY VAI+AV+EILQEYDND +FPAFGFGA++PPDFK HEYPLNGD+ N FCKGV+GV++AY+ AL VK F PVIRQV++L+KEH DGSHYF+LLILT+G+V+DW+ETKRAVIEAS LPVSIIV+G+G F+DM+ LDQDF LL+VGN++A RDNVQFVPMR+FLR AADGS +IRWNKV+LAKEVLAELP Q++ YM ++ L P ++ + S K+L Q +LRRC T+
Sbjct: 1 MTEKSKVLISLSCRNLPTESFEMYYATLRVATGGYFHDKDTISTEKVKDSKDIDFIQKLQLEYIFEEKQIIRIELHGIYFGESACVATL--EC--SVGRIIHSGGELS---RFTEWCWKSITCEIEIIYKVTEDAASKDNLEIKMQGYGLDKKDIFGKSDPYVIIYRRNDKGKLIRTYRSEVVKNTLNPDWKAVVASLERLCGNDLDCELIFKCFDWDGANGDPEDMDTEFDELIGEFTTTTRYLLSANGEQKKFELVNSRKKKKKKNYQHSGLITIRTIQTITDLSFLDYMFGGTDLNFIVAIDLTSSNGDVEDPT-SLHYMDVN-NTNEYSVAIQAVLEILQEYDNDEMFPAFGFGARVPPDFKISHEYPLNGDYSNPFCKGVEGVMKAYREALLQVKLSGPTHFAPVIRQVSNLSKEHRDGSHYFILLILTDGSVDDWVETKRAVIEASYLPVSIIVIGVGGRKFSDMEILDQDFKLLRVGNDQACRDNVQFVPMRRFLRAAADGSDSIRWNKVSLAKEVLAELPVQVLHYMSRHKGAL-----GPRRSEHYRYCSMKDLLRQFSQDTRLRRCATS 565
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000064685.1 (SMESG000064685.1) HSP 1 Score: 509.605 bits (1311), Expect = 7.709e-174 Identity = 268/581 (46.13%), Postives = 377/581 (64.89%), Query Frame = 1
Query: 10 KSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSNPDFTSQLVVEYVFEEKQILAATIF-YQDSASQEKIYGHCFSNMGRIIHNGGSIEVPIKIESNELNNMKN--KPTFIIKLKEDSVKKNNFMMKMSGFDLDKKDLFGKSDPYVILFKKSDKGKWIRTYRTEIIKNNLNPDWKSIPICLNKLCDGDINKEILARCFDWDGAEGDPEDMDAELDELIGESVFTCQHLIESEN-NTVIIQLINHKKQKKKRSYINSGKIQIIADFSMQNYTFLDYMFSGIDLNFIVAVDMSIPKLNIEDQIESIRLFNVTRQSNEYEVAIKAVIEILQEYDNDNLFPAFGFGAQIPPDFKECHEYPLNGDFQNAFCKGVDGVLRAYQTALKTVKSMNTACFTPVIRQVNSLAKEHCDGSHYFVLLILTNGTVEDWIETKRAVIEASSLPVSIIVVGIGSGAFTDMKTLDQDFGLLKVGNEKASRDNVQFVPMRKFLRMAADGSKTIRWNKVALAKEVLAELPDQLVAYMKQNDVRLKFCDNSPVHKQYDNFKSPKELQHQKLRRCVTAHVNIRPNSGS 1740
K KV+IS+ +L + Y + V G+ H +DT+KTE + F ++L +EY+FEEKQ++ IF Y + + + G ++GR+IH+GG I P++I +NE P I ++ED K N +K+ G L K ++FGK+DPY+++F+ +++ ++++ YRTE++KN NPDW I + +LC+ D+N + R + DG + E++D D+L+GE T + LI+ +LIN KK+KKK+SY+NSG I + A + TFLD+MF G++LNFIVA+D+++ N + + S F +NEY VAI+AV+EILQEYDND LFPAFGFGA++PPD+K CHEYPLNGDF+N +C+G +GV+ AYQ LK VK CF+PVIR ++ LAK G HYFVLLILT+G+V+DW+ETK+AV+E S LPVSIIVVG+G G F+DM+TLDQDFGLL V NEKA RDNVQFV MR++LR+AADGS IRW+KVALAK+VLAELP Q+ YM + + +N P + F S C+ + + PNS S
Sbjct: 6 KPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVILKPLEI-TNEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLS--NGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSS-----------CLRQNCSSDPNSLS 572 The following BLAST results are available for this feature:
BLAST of Copine-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Copine-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Copine-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Copine-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Copine-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Copine-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Copine-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Copine-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30016898 ID=SMED30016898|Name=Copine-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1922bpback to top protein sequence of SMED30016898-orf-1 >SMED30016898-orf-1 ID=SMED30016898-orf-1|Name=SMED30016898-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=628bp MPTKSKVIISVGCRHLPLEVIRAYRVTLDVGFEGFSHHKDTMKTEFLETSback to top Annotated Terms
The following terms have been associated with this transcript:
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