Programmed cell death protein 6

Overview
NameProgrammed cell death protein 6
Smed IDSMED30016839
Length (bp)673
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Programmed cell death protein 6 (SMED30016839) t-SNE clustered cells

Violin plots show distribution of expression levels for Programmed cell death protein 6 (SMED30016839) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Programmed cell death protein 6 (SMED30016839) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Programmed cell death protein 6 (SMED30016839) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016839

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30016839SMESG000036586.1 dd_Smed_v4_3585_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30016839SMESG000036586.1 dd_Smed_v4_3585_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016839SMESG000023147.1 SMESG000036586.1 Contig37626newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016839SMESG000023147.1 SMESG000036586.1 Contig37626uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Human
Match: PDCD6 (programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765])

HSP 1 Score: 243.047 bits (619), Expect = 1.315e-81
Identity = 112/167 (67.07%), Postives = 139/167 (83.23%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D ++L+ VFQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+ FGYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:   24 DQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Human
Match: PDCD6 (programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765])

HSP 1 Score: 236.498 bits (602), Expect = 5.857e-79
Identity = 111/167 (66.47%), Postives = 138/167 (82.63%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D ++L+ VFQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+  GYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:   24 DQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALS--GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 188
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Human
Match: PDCD6 (programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765])

HSP 1 Score: 175.637 bits (444), Expect = 5.082e-56
Identity = 79/120 (65.83%), Postives = 100/120 (83.33%), Query Frame = 1 
Query:  214 MFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+ FGYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:    1 MFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 120

HSP 2 Score: 47.3654 bits (111), Expect = 1.367e-6
Identity = 31/80 (38.75%), Postives = 45/80 (56.25%), Query Frame = 1 
Query:   94 VFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTI 333
            VF+  D+D SG I++ EL+QALS G     + +   ++I  FDR   GQI+F++F Q    +    + FR YD D  G I
Sbjct:   28 VFRTYDRDNSGMIDKNELKQALS-GFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWI 106
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Human
Match: PEF1 (penta-EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30009])

HSP 1 Score: 147.132 bits (370), Expect = 8.214e-43
Identity = 77/170 (45.29%), Postives = 102/170 (60.00%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKF-DRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYS 570
            PN DP   Y  FQ VD D SG I+  EL+QAL N  W+ FN ET  +MI MFD+  +G+I    F  LWK++  W+N F+ YDRD SG+I   EL+ AL+  GY LS  F  LL+ ++  R     +  D FIQ C  LQ LT AFR  DT + G I++++E F+T+  S
Sbjct:  113 PNVDPE-AYSWFQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 281
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Human
Match: SRI (sorcin [Source:HGNC Symbol;Acc:HGNC:11292])

HSP 1 Score: 131.339 bits (329), Expect = 8.390e-38
Identity = 70/174 (40.23%), Postives = 101/174 (58.05%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSN----GTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            P    + LY  F  V   + G I+  ELQ+ L+     G + PFN ET RLM+ M DRD +G + FNEF++LW  +  W+  F S+D D SGT+D  EL+ ALT+ G+RLS    N + +++   G+  I FDD+I  CV L+ LT++FR  DT   G +   Y+ F+  V S+
Sbjct:   13 PGQTQDPLYGYFAAV-AGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK--ITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV 183
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Celegans
Match: M04F3.4 (pep chromosome:WBcel235:I:4771348:4773070:-1 gene:WBGene00019770.1 transcript:M04F3.4b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:M04F3.4)

HSP 1 Score: 224.557 bits (571), Expect = 4.843e-75
Identity = 111/177 (62.71%), Postives = 129/177 (72.88%), Query Frame = 1 
Query:   49 MAYYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            MA+ QPN     L Q+F  VDKDRSG I+  ELQ ALSNGTW PFNPET RLMIGMFD + +G I+F EFQ LW+Y+ DW N FR +D DGSG ID++EL  ALT FGYRLS  F+N+L+ KFDR     I FDDFIQ CV LQTLT AFR  DTD DG I + YEQFLT+V+SL +
Sbjct:    1 MAFQQPN-----LQQIFSSVDKDRSGQISSDELQTALSNGTWNPFNPETCRLMIGMFDSNGDGAINFQEFQALWRYINDWTNCFRGFDTDGSGNIDKSELTNALTQFGYRLSPQFYNILMHKFDRSHSNRINFDDFIQLCVVLQTLTAAFRDVDTDRDGVITVGYEQFLTMVFSLKM 172
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Celegans
Match: M04F3.4 (pep chromosome:WBcel235:I:4771348:4773673:-1 gene:WBGene00019770.1 transcript:M04F3.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:M04F3.4)

HSP 1 Score: 224.557 bits (571), Expect = 4.843e-75
Identity = 111/177 (62.71%), Postives = 129/177 (72.88%), Query Frame = 1 
Query:   49 MAYYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            MA+ QPN     L Q+F  VDKDRSG I+  ELQ ALSNGTW PFNPET RLMIGMFD + +G I+F EFQ LW+Y+ DW N FR +D DGSG ID++EL  ALT FGYRLS  F+N+L+ KFDR     I FDDFIQ CV LQTLT AFR  DTD DG I + YEQFLT+V+SL +
Sbjct:    1 MAFQQPN-----LQQIFSSVDKDRSGQISSDELQTALSNGTWNPFNPETCRLMIGMFDSNGDGAINFQEFQALWRYINDWTNCFRGFDTDGSGNIDKSELTNALTQFGYRLSPQFYNILMHKFDRSHSNRINFDDFIQLCVVLQTLTAAFRDVDTDRDGVITVGYEQFLTMVFSLKM 172
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Celegans
Match: M04F3.4 (pep chromosome:WBcel235:I:4771600:4773026:-1 gene:WBGene00019770.1 transcript:M04F3.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:M04F3.4)

HSP 1 Score: 224.557 bits (571), Expect = 4.843e-75
Identity = 111/177 (62.71%), Postives = 129/177 (72.88%), Query Frame = 1 
Query:   49 MAYYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            MA+ QPN     L Q+F  VDKDRSG I+  ELQ ALSNGTW PFNPET RLMIGMFD + +G I+F EFQ LW+Y+ DW N FR +D DGSG ID++EL  ALT FGYRLS  F+N+L+ KFDR     I FDDFIQ CV LQTLT AFR  DTD DG I + YEQFLT+V+SL +
Sbjct:    1 MAFQQPN-----LQQIFSSVDKDRSGQISSDELQTALSNGTWNPFNPETCRLMIGMFDSNGDGAINFQEFQALWRYINDWTNCFRGFDTDGSGNIDKSELTNALTQFGYRLSPQFYNILMHKFDRSHSNRINFDDFIQLCVVLQTLTAAFRDVDTDRDGVITVGYEQFLTMVFSLKM 172
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Celegans
Match: cal-4 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:G5EDZ8])

HSP 1 Score: 67.781 bits (164), Expect = 5.729e-14
Identity = 45/145 (31.03%), Postives = 72/145 (49.66%), Query Frame = 1 
Query:   91 QVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQN------TFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDF---IQSCVSLQTLTNAF 498
            Q F+  DKD +  +N  EL +A+      P   E +  M+  +D D NG+I F EF ++ K +    +       F+ +D+DG+G I   E K  +T+ G R S+   + +IR+ D+ G   I  D+F   +   VS  T T+ F
Sbjct:   27 QAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLN-MVNEYDVDGNGKIDFGEFCKMMKEMNKETDQELIRLAFKVFDKDGNGYITAQEFKHFMTTMGERFSEEEVDEIIREVDKDGDEQIDLDEFVNMVAPIVSDGTKTDPF 170
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Celegans
Match: cal-4 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:G5EDZ8])

HSP 1 Score: 67.781 bits (164), Expect = 1.105e-13
Identity = 45/145 (31.03%), Postives = 72/145 (49.66%), Query Frame = 1 
Query:   91 QVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQN------TFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDF---IQSCVSLQTLTNAF 498
            Q F+  DKD +  +N  EL +A+      P   E +  M+  +D D NG+I F EF ++ K +    +       F+ +D+DG+G I   E K  +T+ G R S+   + +IR+ D+ G   I  D+F   +   VS  T T+ F
Sbjct:   53 QAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLN-MVNEYDVDGNGKIDFGEFCKMMKEMNKETDQELIRLAFKVFDKDGNGYITAQEFKHFMTTMGERFSEEEVDEIIREVDKDGDEQIDLDEFVNMVAPIVSDGTKTDPF 196
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Fly
Match: Alg-2 (gene:FBgn0086378 transcript:FBtr0301810)

HSP 1 Score: 245.358 bits (625), Expect = 5.882e-83
Identity = 119/178 (66.85%), Postives = 141/178 (79.21%), Query Frame = 1 
Query:   49 MAY-YQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            MAY +    D  +L+ VFQ+VDKDRSG I+  ELQ ALSNGTW+ FNPET+RLMIGMFDR+N G +SF +F  LWKYV DWQN FRS+DRD SG ID+ ELK ALTSFGYRLSD+  ++L+RKFDR GRGTI FDDFIQ C+ L TLT AFR  DTDLDG I I+YEQFL++V+SL +
Sbjct:    1 MAYNHDGMPDQQFLWDVFQRVDKDRSGHISADELQVALSNGTWSAFNPETIRLMIGMFDRENKGTVSFKDFGALWKYVTDWQNCFRSFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKFDRFGRGTILFDDFIQCCIVLYTLTTAFRQHDTDLDGIITIHYEQFLSMVFSLKI 178
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Fly
Match: CG17765 (gene:FBgn0033529 transcript:FBtr0088274)

HSP 1 Score: 143.28 bits (360), Expect = 1.489e-42
Identity = 71/156 (45.51%), Postives = 92/156 (58.97%), Query Frame = 1 
Query:   97 FQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLV 564
            F  VD+DRSG IN  ELQ AL NG    F+    +LMI MFD D +G I   EF++L+ Y+  W   F++YD+D SG I+  EL  A T  G+R S  F N L++K D QG   ++ D FI  CV +Q  T AFR  DT  +G I I +E FLT+ 
Sbjct:   39 FSMVDRDRSGKINASELQAALVNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFLTVA 194
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Fly
Match: CalpB (gene:FBgn0025866 transcript:FBtr0076343)

HSP 1 Score: 85.1149 bits (209), Expect = 7.443e-19
Identity = 43/126 (34.13%), Postives = 68/126 (53.97%), Query Frame = 1 
Query:  181 FNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTD--------LDGWIQ 534
            F+ + VR M+ M D+D +G++ F EF+ L   +  W+  F+ YD   +G+ID   L+ AL S GY L++   N L  ++  +  G I FDDF+   + ++T    FR  DTD        LD W++
Sbjct:  796 FSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSR-EGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLE 920
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Fly
Match: CalpB (gene:FBgn0025866 transcript:FBtr0304675)

HSP 1 Score: 85.1149 bits (209), Expect = 7.443e-19
Identity = 43/126 (34.13%), Postives = 68/126 (53.97%), Query Frame = 1 
Query:  181 FNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTD--------LDGWIQ 534
            F+ + VR M+ M D+D +G++ F EF+ L   +  W+  F+ YD   +G+ID   L+ AL S GY L++   N L  ++  +  G I FDDF+   + ++T    FR  DTD        LD W++
Sbjct:  796 FSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSR-EGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLE 920
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Fly
Match: CalpA (gene:FBgn0012051 transcript:FBtr0340532)

HSP 1 Score: 80.8777 bits (198), Expect = 2.589e-17
Identity = 41/126 (32.54%), Postives = 69/126 (54.76%), Query Frame = 1 
Query:  181 FNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTD--------LDGWIQ 534
            F+ +  R M+ M D D +G++ F EF+ L   +  W+  F+ YD + +G +   +L+ AL S GY L++   N+L  ++  +  G IAFDDFI   V ++T  + F+  DT+        L+ WI+
Sbjct:  714 FSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLREALNSAGYHLNNRVLNVLGHRYGSRD-GKIAFDDFIMCAVKIKTYIDIFKERDTEKNETATFTLEEWIE 838
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Zebrafish
Match: pdcd6 (programmed cell death 6 [Source:ZFIN;Acc:ZDB-GENE-040426-1307])

HSP 1 Score: 242.276 bits (617), Expect = 1.678e-81
Identity = 117/184 (63.59%), Postives = 145/184 (78.80%), Query Frame = 1 
Query:   49 MAY---YQPNN------DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            MAY   Y+P +      D  +L+ +FQ+VDKDRSGAI+  ELQQALSNGTWTPFNP TVR +I MFDR+N G ++FNEF  +WKY+ DWQN FR+YDRD SG ID+NELK ALT FGYRLSD F+N LI KFDRQ RG +AFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+++
Sbjct:    1 MAYHNQYRPPHYNSAPPDQGFLWNIFQRVDKDRSGAISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKGGVNFNEFAGVWKYITDWQNIFRTYDRDNSGFIDKNELKQALTGFGYRLSDQFYNTLIEKFDRQKRGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWIQVSYEQYLSMVFNV 184
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Zebrafish
Match: sri (sorcin [Source:ZFIN;Acc:ZDB-GENE-040426-1356])

HSP 1 Score: 129.798 bits (325), Expect = 2.298e-37
Identity = 68/174 (39.08%), Postives = 98/174 (56.32%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            P    + LY  F  +   + G I+  ELQ  L+    +G + PFN ET RLMI M DRD +  + FNEF++LW  +  W+  F S DRD SGT+D  E+  A++S GYRLS    N +I+++  QG+  I FDD++  CV L++LT+ FR  D    G     Y+ F+    S+
Sbjct:   20 PGQQQDPLYGYFTAI-AGQDGQISAEELQACLTQANFSGGYRPFNLETCRLMISMLDRDMSYSMGFNEFKELWAVLNGWKQHFMSIDRDMSGTVDPQEMNQAISSMGYRLSPQAMNSIIKRYSSQGK--ITFDDYVACCVKLRSLTDVFRKRDQAQQGMATFQYDDFIHCTMSI 190
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Zebrafish
Match: pef1 (penta-EF-hand domain containing 1 [Source:NCBI gene;Acc:445249])

HSP 1 Score: 131.339 bits (329), Expect = 5.520e-37
Identity = 69/166 (41.57%), Postives = 100/166 (60.24%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFD-RQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLT 558
            P  +P   YQ F  VD D+SG IN  EL+QAL N   + FN ET  +M+ MFD+  +G++    F  LW ++  W+  F+ +DRD SG+I+ NE+  AL+  GY LS  F   L+ ++  R G G +  D FIQ C  LQ++T AFR  DT + G ++++YE FL+
Sbjct:   99 PGVNPE-AYQWFSTVDSDQSGYINAKELKQALMNFNNSSFNDETCIMMLNMFDKTKSGRVDVFGFSALWTFLQQWRAAFQQFDRDRSGSINTNEMHQALSQMGYNLSPQFIQELVNRYSVRGGTGVLQLDRFIQVCTQLQSMTQAFREKDTGMTGNVRMSYEDFLS 263
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Zebrafish
Match: GCA (zgc:92027 [Source:ZFIN;Acc:ZDB-GENE-040930-3])

HSP 1 Score: 126.716 bits (317), Expect = 5.125e-36
Identity = 62/174 (35.63%), Postives = 102/174 (58.62%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            P  DP W Y  F  +   + G ++  ELQ+ L+    +G++TPF+ ET R+MI + DRD  G++ FNEF++L+  +  W+  F   DRD SGT++  E+  ++ + GYR+S    + +++++ R G+  I FDD++  CV L+ LT+ FR  DT   G +   Y+ F+    SL
Sbjct:   37 PAQDPMWGY--FTAI-AGQDGEVDAEELQRCLTQTGISGSYTPFSLETCRIMIALLDRDYTGKMGFNEFKELFGVLNGWKQNFMMVDRDHSGTVEPYEMSQSIANMGYRVSPRVLDAIVKRYSRSGK--IYFDDYVACCVKLKALTDHFRKRDTMQQGMVNFQYDDFILCTISL 205
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Zebrafish
Match: GCA (zgc:92027 [Source:ZFIN;Acc:ZDB-GENE-040930-3])

HSP 1 Score: 121.709 bits (304), Expect = 4.974e-34
Identity = 59/165 (35.76%), Postives = 98/165 (59.39%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYE 546
            P  DP W Y  F  +   + G ++  ELQ+ L+    +G++TPF+ ET R+MI + DRD  G++ FNEF++L+  +  W+  F   DRD SGT++  E+  ++ + GYR+S    + +++++ R G+  I FDD++  CV L+ LT+ FR  DT   G +   Y+
Sbjct:   38 PAQDPMWGY--FTAI-AGQDGEVDAEELQRCLTQTGISGSYTPFSLETCRIMIALLDRDYTGKMGFNEFKELFGVLNGWKQNFMMVDRDHSGTVEPYEMSQSIANMGYRVSPRVLDAIVKRYSRSGK--IYFDDYVACCVKLKALTDHFRKRDTMQQGMVNFQYD 197
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Xenopus
Match: pdcd6 (programmed cell death 6 [Source:NCBI gene;Acc:493366])

HSP 1 Score: 239.58 bits (610), Expect = 2.221e-80
Identity = 115/183 (62.84%), Postives = 144/183 (78.69%), Query Frame = 1 
Query:   49 MAYYQPNNDP--------NWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            MAYYQ  N P        ++L+ VFQ+VD+DRSG I+  ELQQALSNGTWTPFNP TV  +I MFDRD+ G ++FNEF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+  GYRLSD F+++LIRKFDRQ RG +AFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+LT+++S+
Sbjct:    1 MAYYQQQNRPPGNTMPDQSFLWNVFQRVDRDRSGVISDTELQQALSNGTWTPFNPATVNSIISMFDRDHKGGVNFNEFSGVWKYITDWQNIFRTYDRDNSGLIDKNELKQALS--GYRLSDQFYDVLIRKFDRQRRGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWIQVSYEQYLTMIFSV 181
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Xenopus
Match: pdcd6 (programmed cell death 6 [Source:NCBI gene;Acc:493366])

HSP 1 Score: 234.572 bits (597), Expect = 2.051e-78
Identity = 106/159 (66.67%), Postives = 132/159 (83.02%), Query Frame = 1 
Query:   97 FQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            F +VD+DRSG I+  ELQQALSNGTWTPFNP TV  +I MFDRD+ G ++FNEF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+ FGYRLSD F+++LIRKFDRQ RG +AFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+LT+++S+
Sbjct:   22 FHRVDRDRSGVISDTELQQALSNGTWTPFNPATVNSIISMFDRDHKGGVNFNEFSGVWKYITDWQNIFRTYDRDNSGLIDKNELKQALSGFGYRLSDQFYDVLIRKFDRQRRGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWIQVSYEQYLTMIFSV 180

HSP 2 Score: 47.7506 bits (112), Expect = 2.718e-6
Identity = 29/80 (36.25%), Postives = 45/80 (56.25%), Query Frame = 1 
Query:   94 VFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTI 333
            +F+  D+D SG I++ EL+QALS G     + +   ++I  FDR   GQ++F++F Q    +    + FR YD D  G I
Sbjct:   88 IFRTYDRDNSGLIDKNELKQALS-GFGYRLSDQFYDVLIRKFDRQRRGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWI 166
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Xenopus
Match: etfdh (electron transfer flavoprotein dehydrogenase [Source:Xenbase;Acc:XB-GENE-972267])

HSP 1 Score: 142.895 bits (359), Expect = 3.137e-41
Identity = 74/170 (43.53%), Postives = 104/170 (61.18%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKF-DRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYS 570
            P  DP   +  FQ VD D SG I+  EL+QAL N  W+ FN ET  +M+ MFD+ N+G+I    F  LW+++  W+N F+ YDRD SG+I++ EL  AL   GY+LS  F  L++ ++  R  +  +  D FIQ C  LQ++T AFR  DT L G  +++YE FLT+  S
Sbjct:  113 PGVDPE-AFSWFQTVDSDHSGYISLKELKQALVNSNWSSFNDETCMMMMNMFDKSNSGRIDLFGFSALWRFIQQWRNLFQQYDRDRSGSINQGELHQALCQMGYQLSPQFVQLVMSRYAQRSVQPGLQLDRFIQICTQLQSMTQAFREKDTGLSGNAKLSYEDFLTMTTS 281
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Xenopus
Match: etfdh (electron transfer flavoprotein dehydrogenase [Source:Xenbase;Acc:XB-GENE-972267])

HSP 1 Score: 142.895 bits (359), Expect = 3.229e-41
Identity = 74/170 (43.53%), Postives = 104/170 (61.18%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKF-DRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYS 570
            P  DP   +  FQ VD D SG I+  EL+QAL N  W+ FN ET  +M+ MFD+ N+G+I    F  LW+++  W+N F+ YDRD SG+I++ EL  AL   GY+LS  F  L++ ++  R  +  +  D FIQ C  LQ++T AFR  DT L G  +++YE FLT+  S
Sbjct:  112 PGVDPE-AFSWFQTVDSDHSGYISLKELKQALVNSNWSSFNDETCMMMMNMFDKSNSGRIDLFGFSALWRFIQQWRNLFQQYDRDRSGSINQGELHQALCQMGYQLSPQFVQLVMSRYAQRSVQPGLQLDRFIQICTQLQSMTQAFREKDTGLSGNAKLSYEDFLTMTTS 280
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Xenopus
Match: sri (sorcin [Source:NCBI gene;Acc:549421])

HSP 1 Score: 124.02 bits (310), Expect = 7.842e-35
Identity = 67/171 (39.18%), Postives = 100/171 (58.48%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            DP  +Y  F  +   + G I+  ELQ+ L+    +G + PF+ ET RLMI M DRD +G++ FNEF++L   +  W+  F +YD D SGT++ +EL  AL + GYRLS    N + +++   GR  I+FDD+I  CV L+ LT+ FR  D    G +   Y+ F+  V S+
Sbjct:   30 DP--MYGYFASI-AGQDGQIDADELQRCLTQAGLSGGYKPFSLETCRLMIAMLDRDMSGKMGFNEFKELGMVINGWRQHFMTYDGDRSGTVEGHELHAALGAMGYRLSPQALNNIAKRYSTNGR--ISFDDYITCCVKLRALTDMFRRRDVSQQGVVNFQYDDFIQSVMSI 195
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Mouse
Match: Pdcd6 (programmed cell death 6 [Source:MGI Symbol;Acc:MGI:109283])

HSP 1 Score: 242.276 bits (617), Expect = 1.778e-81
Identity = 112/167 (67.07%), Postives = 139/167 (83.23%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D ++L+ VFQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+ FGYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:   24 DQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Mouse
Match: Pdcd6 (programmed cell death 6 [Source:MGI Symbol;Acc:MGI:109283])

HSP 1 Score: 235.343 bits (599), Expect = 8.549e-79
Identity = 111/167 (66.47%), Postives = 138/167 (82.63%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D ++L+ VFQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+  GYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:   24 DQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALS--GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 188
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Mouse
Match: Pef1 (penta-EF hand domain containing 1 [Source:MGI Symbol;Acc:MGI:1915148])

HSP 1 Score: 145.206 bits (365), Expect = 2.343e-42
Identity = 76/170 (44.71%), Postives = 102/170 (60.00%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKF-DRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYS 570
            PN DP   Y  FQ VD D SG I+  EL+QAL N  W+ FN ET  +MI MFD+  +G+I    F  LWK++  W+N F+ YDRD SG+I   EL+ AL+  GY LS  F  LL+ ++  R     +  D FI+ C  LQ LT AFR  DT + G I++++E F+T+  S
Sbjct:  104 PNVDPE-AYSWFQSVDADHSGYISLKELKQALVNSNWSSFNDETCLMMINMFDKTKSGRIDVAGFSALWKFLQQWRNLFQQYDRDRSGSISSTELQQALSQMGYNLSPQFTQLLVSRYCARSAIPAMQLDCFIKVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 272
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Mouse
Match: Pef1 (penta-EF hand domain containing 1 [Source:MGI Symbol;Acc:MGI:1915148])

HSP 1 Score: 145.206 bits (365), Expect = 2.343e-42
Identity = 76/170 (44.71%), Postives = 102/170 (60.00%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKF-DRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYS 570
            PN DP   Y  FQ VD D SG I+  EL+QAL N  W+ FN ET  +MI MFD+  +G+I    F  LWK++  W+N F+ YDRD SG+I   EL+ AL+  GY LS  F  LL+ ++  R     +  D FI+ C  LQ LT AFR  DT + G I++++E F+T+  S
Sbjct:  104 PNVDPE-AYSWFQSVDADHSGYISLKELKQALVNSNWSSFNDETCLMMINMFDKTKSGRIDVAGFSALWKFLQQWRNLFQQYDRDRSGSISSTELQQALSQMGYNLSPQFTQLLVSRYCARSAIPAMQLDCFIKVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 272
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Mouse
Match: Sri (sorcin [Source:MGI Symbol;Acc:MGI:98419])

HSP 1 Score: 130.183 bits (326), Expect = 1.750e-37
Identity = 68/174 (39.08%), Postives = 102/174 (58.62%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSN----GTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            P    + LY  F  V   + G I+  ELQ+ L+     G + PFN ET RLM+ M DRD +G + FNEF++LW  +  W+  F S+D D SGT+D  EL+ ALT+ G+RLS    N + +++   G+  I FDD+I  CV L+ LT++FR  D+   G +  +Y+ F+  V ++
Sbjct:   13 PGQTQDPLYGYFAAV-AGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQTVNSVAKRYSTSGK--ITFDDYIACCVKLRALTDSFRRRDSGQQGVVNFSYDDFIQCVMTV 183
[Close]
BLAST of Programmed cell death protein 6 vs. UniProt/SwissProt
Match: sp|O75340|PDCD6_HUMAN (Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6 PE=1 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 6.315e-81
Identity = 112/167 (67.07%), Postives = 139/167 (83.23%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D ++L+ VFQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+ FGYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:   24 DQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190
[Close]
BLAST of Programmed cell death protein 6 vs. UniProt/SwissProt
Match: sp|P12815|PDCD6_MOUSE (Programmed cell death protein 6 OS=Mus musculus OX=10090 GN=Pdcd6 PE=1 SV=2)

HSP 1 Score: 242.276 bits (617), Expect = 1.244e-80
Identity = 112/167 (67.07%), Postives = 139/167 (83.23%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D ++L+ VFQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID+NELK AL+ FGYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:   24 DQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190
[Close]
BLAST of Programmed cell death protein 6 vs. UniProt/SwissProt
Match: sp|G3V7W1|PDCD6_RAT (Programmed cell death protein 6 OS=Rattus norvegicus OX=10116 GN=Pdcd6 PE=2 SV=1)

HSP 1 Score: 241.121 bits (614), Expect = 3.401e-80
Identity = 111/167 (66.47%), Postives = 139/167 (83.23%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D ++L+ VFQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N   ++F+EF  +WKY+ DWQN FR+YDRD SG ID++ELK AL+ FGYRLSD F ++LIRKFDRQGRG IAFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+S+
Sbjct:   24 DQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKHELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190
[Close]
BLAST of Programmed cell death protein 6 vs. UniProt/SwissProt
Match: sp|Q94743|SORCN_SCHJA (Sorcin OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 187.578 bits (475), Expect = 2.696e-59
Identity = 94/167 (56.29%), Postives = 116/167 (69.46%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            D N L  +F +VD D+SG+I+  ELQ +LSNG  TP N  TV+LM+ MFDRD NG I+FNEF  L+KYV DWQ  FR YDRD SG+ID NE   AL SFGY LS  F NL++R+FDR  RG+IAFDDFI +CV LQTLT  F  +D    G    ++EQFLT  +++
Sbjct:    4 DTNSLRHIFSRVDADKSGSISANELQTSLSNGLGTPLNIRTVQLMVAMFDRDMNGTINFNEFLGLFKYVQDWQTCFRRYDRDNSGSIDLNEFSNALISFGYHLSPQFVNLMMRRFDRN-RGSIAFDDFIYACVCLQTLTREFSRYDCRGIGHTVFSFEQFLTSAFAV 169
[Close]
BLAST of Programmed cell death protein 6 vs. UniProt/SwissProt
Match: sp|Q9UBV8|PEF1_HUMAN (Peflin OS=Homo sapiens OX=9606 GN=PEF1 PE=1 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 3.945e-42
Identity = 77/170 (45.29%), Postives = 102/170 (60.00%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKF-DRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYS 570
            PN DP   Y  FQ VD D SG I+  EL+QAL N  W+ FN ET  +MI MFD+  +G+I    F  LWK++  W+N F+ YDRD SG+I   EL+ AL+  GY LS  F  LL+ ++  R     +  D FIQ C  LQ LT AFR  DT + G I++++E F+T+  S
Sbjct:  113 PNVDPE-AYSWFQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 281
[Close]
BLAST of Programmed cell death protein 6 vs. TrEMBL
Match: A0A2T7NIJ8 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_19165 PE=4 SV=1)

HSP 1 Score: 278.1 bits (710), Expect = 1.692e-92
Identity = 127/167 (76.05%), Postives = 150/167 (89.82%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            DPN+L  +FQ++DKDRSG+I+ +ELQ+ALSNGTWTPFNPETVR+MIGMFDRDN+G I+F EFQ LWKYV DWQN FRSYDRDGSG+ID+NELKMALT FGYRLSD F+ +L++KFDRQG+G +AFDDFIQ CV LQTLT+AFR  DTD DGWI+I+YEQFLTLV+SL
Sbjct:    3 DPNFLAGIFQRIDKDRSGSISAHELQEALSNGTWTPFNPETVRMMIGMFDRDNSGTINFQEFQALWKYVTDWQNCFRSYDRDGSGSIDKNELKMALTRFGYRLSDRFYEVLVKKFDRQGKGVVAFDDFIQCCVVLQTLTSAFRMHDTDQDGWIRISYEQFLTLVFSL 169
[Close]
BLAST of Programmed cell death protein 6 vs. TrEMBL
Match: A0A1S3HVK3 (programmed cell death protein 6-like isoform X3 OS=Lingula unguis OX=7574 GN=LOC106157854 PE=4 SV=1)

HSP 1 Score: 276.174 bits (705), Expect = 1.180e-91
Identity = 134/177 (75.71%), Postives = 150/177 (84.75%), Query Frame = 1 
Query:   55 YYQPNN---DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLN 576
            Y QP     DP +L+ VFQ+VDKD SG IN +ELQ ALSNGTWTPFNPETVRLMIGMFDRDNNG I+F EFQ LWKYV DWQNTFRSYDRD SG ID+NELK+AL SFGYRLSD F+++LIRKFDRQGRG +AFDDFIQ CV +QTLT+AFR  DTD DGWIQI+YEQFLTLV+S+ 
Sbjct:    5 YQQPAPGGVDPQFLWGVFQRVDKDHSGHINSFELQSALSNGTWTPFNPETVRLMIGMFDRDNNGTINFQEFQSLWKYVTDWQNTFRSYDRDNSGAIDKNELKIALQSFGYRLSDRFYDILIRKFDRQGRGQVAFDDFIQCCVVMQTLTSAFRYHDTDQDGWIQISYEQFLTLVFSMK 181
[Close]
BLAST of Programmed cell death protein 6 vs. TrEMBL
Match: A0A194APN4 (Putative programmed cell death protein 6-like protein isoform X2 OS=Pinctada fucata OX=50426 PE=4 SV=1)

HSP 1 Score: 273.863 bits (699), Expect = 1.411e-90
Identity = 132/167 (79.04%), Postives = 147/167 (88.02%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            DPN+L+ VF KVD DRSG I+ +EL QALSNGTWTPFNPETVRLMIGMFDRDN G I+F EFQ LWKYV DWQNTFRSYDRD SG+IDRNELK ALTSFGYRLSD F+++L+RKFDRQGRGT+AFDDFIQ  V LQTLTNAFR  D+D DGWIQI+YEQFLTLV++L
Sbjct:   19 DPNFLWNVFNKVDTDRSGQISAHELGQALSNGTWTPFNPETVRLMIGMFDRDNTGTINFQEFQSLWKYVTDWQNTFRSYDRDNSGSIDRNELKTALTSFGYRLSDKFYDILVRKFDRQGRGTVAFDDFIQCSVVLQTLTNAFRYHDSDQDGWIQISYEQFLTLVFNL 185
[Close]
BLAST of Programmed cell death protein 6 vs. TrEMBL
Match: A0A3S1BKU5 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_009130 PE=4 SV=1)

HSP 1 Score: 273.478 bits (698), Expect = 1.670e-90
Identity = 130/170 (76.47%), Postives = 146/170 (85.88%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            P  DPN+L  +FQ VDKDRSG I   ELQQAL NGTWTPFNPETVRLMIGMFDRDN+G I+F EFQ LWKYV DWQ  FRSYDRDGSG+IDRNEL+ ALT+FGYRLS NF+++LIRKFDRQGRG +AFDDF+Q  V LQTLTN+FR +DTD DGWIQI+YEQFLTLV+SL
Sbjct:   11 PGVDPNYLSGIFQSVDKDRSGQITATELQQALGNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQSLWKYVTDWQGCFRSYDRDGSGSIDRNELQTALTNFGYRLSPNFYSILIRKFDRQGRGQVAFDDFVQCAVVLQTLTNSFRAYDTDQDGWIQISYEQFLTLVFSL 180
[Close]
BLAST of Programmed cell death protein 6 vs. TrEMBL
Match: K1QIZ7 (Programmed cell death protein 6 OS=Crassostrea gigas OX=29159 GN=CGI_10023297 PE=4 SV=1)

HSP 1 Score: 273.092 bits (697), Expect = 2.701e-90
Identity = 131/167 (78.44%), Postives = 147/167 (88.02%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            DPN+L+ +FQ+VDKDRSG I+  ELQ ALSNGTWTPFNPETVRLMIGMFD+DN+G I+F EF  LWKYV DWQNTFRSYDRD SG+IDRNELK ALTSFGYRLSD F+ +LIRKFDRQGRGT+AFDDFIQ CV LQTLT+AFR +DTD DGWIQI YEQFL LV++L
Sbjct:   22 DPNFLWGIFQRVDKDRSGQISVNELQTALSNGTWTPFNPETVRLMIGMFDKDNSGTINFQEFSSLWKYVTDWQNTFRSYDRDNSGSIDRNELKQALTSFGYRLSDKFYEILIRKFDRQGRGTVAFDDFIQCCVVLQTLTSAFRFYDTDQDGWIQIGYEQFLMLVFNL 188
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Cavefish
Match: pdcd6 (programmed cell death 6 [Source:NCBI gene;Acc:103024788])

HSP 1 Score: 242.276 bits (617), Expect = 1.168e-81
Identity = 113/173 (65.32%), Postives = 140/173 (80.92%), Query Frame = 1 
Query:   55 YYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            Y Q   D  +L+ +FQ+VDKDRSGAI+  ELQQALSNGTWTPFNP TVR +I MFDR+N G ++FNEF  +WKY+ DWQN FR+YDRD SG ID+NELK ALT FGYRLSD F+N LI KFDRQ +G +AFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+++
Sbjct:   12 YNQAPPDQAFLWNIFQRVDKDRSGAISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKGGVNFNEFAGVWKYITDWQNIFRTYDRDNSGFIDKNELKQALTGFGYRLSDQFYNTLIEKFDRQRKGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWIQVSYEQYLSMVFNI 184
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Cavefish
Match: pdcd6 (programmed cell death 6 [Source:NCBI gene;Acc:103024788])

HSP 1 Score: 216.853 bits (551), Expect = 1.517e-71
Identity = 104/175 (59.43%), Postives = 133/175 (76.00%), Query Frame = 1 
Query:   55 YYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPE--TVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            Y Q   D  +L+ +FQ+VDKDRSGAI+  ELQQALSNG  +  +P   T    + MFDR+N G ++FNEF  +WKY+ DWQN FR+YDRD SG ID+NELK ALT FGYRLSD F+N LI KFDRQ +G +AFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+++
Sbjct:   12 YNQAPPDQAFLWNIFQRVDKDRSGAISDTELQQALSNGMCSKHSPLLLTTVTNVSMFDRENKGGVNFNEFAGVWKYITDWQNIFRTYDRDNSGFIDKNELKQALTGFGYRLSDQFYNTLIEKFDRQRKGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWIQVSYEQYLSMVFNI 186
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Cavefish
Match: sri (sorcin-like [Source:NCBI gene;Acc:103031467])

HSP 1 Score: 132.494 bits (332), Expect = 2.126e-38
Identity = 69/170 (40.59%), Postives = 99/170 (58.24%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYS 570
            DP  L+  F  V   + G I+  ELQ  L+    +G + PFN ET RLMI M DRD +GQ+ FNEF++LW  +  W+  F S DRD SGT+D  E+  A+ S GYRLS    N++++++   G+  I FDD++  CV L++LT+ FR  D    G     Y+ F+  + S
Sbjct:   26 DP--LFGYFSAV-AGQDGQISAEELQACLTQANFSGGYKPFNLETCRLMINMLDRDMSGQMGFNEFKELWAVMNGWKQHFMSIDRDMSGTVDAQEMNQAICSMGYRLSPQAMNIIVKRYSTHGK--ITFDDYVACCVKLRSLTDIFRRRDQAQQGAATFQYDDFIQCIMS 190
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Cavefish
Match: pef1 (penta-EF-hand domain containing 1 [Source:NCBI gene;Acc:103033186])

HSP 1 Score: 133.265 bits (334), Expect = 1.186e-37
Identity = 70/170 (41.18%), Postives = 101/170 (59.41%), Query Frame = 1 
Query:   64 PNNDPNWL----YQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQG-RGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLT 558
            P N P  +    YQ FQ VD DRSG IN  EL+QAL N   + FN ET  +M+ MFD+  +G++    F  LW Y+  W+  F  +DRD SG+I+ +E+  AL+  GY +S  F   L+ ++  +G   ++  D FIQ C  LQ++T AFR  DT + G +++NYE FL+
Sbjct:  109 PGNMPPGVNPEAYQWFQTVDTDRSGHINLKELKQALLNSNNSAFNDETCLMMLNMFDKTKSGRMDVFGFSALWMYLQQWRAVFNQFDRDRSGSINSSEMHQALSQMGYNMSPQFIETLVSRYCVRGMNNSLQLDRFIQVCTQLQSMTQAFREKDTAMTGNVRMNYEDFLS 278
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Cavefish
Match: zgc:92027 (grancalcin-like [Source:NCBI gene;Acc:103040268])

HSP 1 Score: 127.102 bits (318), Expect = 7.341e-36
Identity = 64/174 (36.78%), Postives = 101/174 (58.05%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            P+ DP W Y  F  +   + G ++  ELQ+ L+    +G++ PF+ ET R+MI M D D +G++ FNEF++L+  +  W+  F   DRD SGT++ +EL  A+ + GYRLS      +I++F R G+  I FDD++  CV L+ LT  FR  D    G +   Y+ F+T   ++
Sbjct:   63 PSQDPMWGY--FTAI-AGQDGEVDAEELQRCLTQTGISGSYMPFSLETCRIMIAMLDTDYSGKMGFNEFKELFTALNGWKQNFMMVDRDNSGTVEPHELSQAIGNMGYRLSPQALGCIIKRFSRGGK--IYFDDYVACCVKLRALTENFRRRDAMQQGAVNFPYDDFITCTMAI 231
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Sea Lamprey
Match: zgc:92027 (grancalcin [Source:HGNC Symbol;Acc:HGNC:15990])

HSP 1 Score: 136.346 bits (342), Expect = 1.397e-40
Identity = 71/174 (40.80%), Postives = 105/174 (60.34%), Query Frame = 1 
Query:   64 PNNDPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            P  DP  L+  F  V   + G I+  ELQ+ L+    +GT+ PF+ ET ++MI M DRD +G++ FNEF++LW  +  W+  F ++DRD SGT+D  EL  AL S GYRLS    N ++++F R  +  I FDD++  CV L+ LT+AFR  DT   G++   Y+ F+    S+
Sbjct:   25 PQQDP--LFGYFSAV-AGQDGQIDAEELQRCLTQSGISGTYQPFSFETCKIMISMLDRDMSGKMGFNEFKELWTALNGWKQNFMAFDRDMSGTVDPGELSQALASMGYRLSPQAINNIVKRFSRDCK--IFFDDYVACCVKLRALTDAFRRRDTAQQGYVNFAYDDFIQCTMSI 193
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Sea Lamprey
Match: capn3a (calpain 3a, (p94) [Source:ZFIN;Acc:ZDB-GENE-040912-97])

HSP 1 Score: 89.7373 bits (221), Expect = 4.247e-21
Identity = 44/129 (34.11%), Postives = 77/129 (59.69%), Query Frame = 1 
Query:  181 FNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLL-IRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLV 564
            F+ E+ R M+ + D D +G++ +N+F+ LW  +  WQ  FR YD D SG++   E+++A+   GY+L++  + ++ +R  D      I FD+FI   + L+ +  AF+ FD D DG I++N  ++L L 
Sbjct:  682 FSLESCRTMVALMDTDLSGKLGYNDFKYLWDKLKFWQQIFRKYDSDKSGSMTSYEMRLAINEAGYQLNNQLYQIITLRHADEN--LNIGFDNFIACLIRLEAMFRAFKAFDKDGDGIIRLNVLEWLQLT 808
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000845.1 (pep scaffold:Pmarinus_7.0:GL481444:15049:20027:-1 gene:ENSPMAG00000000771.1 transcript:ENSPMAT00000000845.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.9593 bits (206), Expect = 1.106e-20
Identity = 41/127 (32.28%), Postives = 71/127 (55.91%), Query Frame = 1 
Query:  181 FNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTL 561
            F+ +  R M+ + DRD +G++   EF  LW+ +  WQ  FR +D D SG ++  E ++AL   G+RL+D     +  ++  +  G I FD+++   V L+T+   F+  + D DG I++   +FL L
Sbjct:   39 FSLDACRNMVSLMDRDGSGKLGIKEFNFLWQRIKSWQQIFRQFDMDHSGNMNGYEFRLALAEAGFRLNDQLTQTITMRYMEEN-GVIDFDNYLCCLVRLETMFRIFQALNKDGDGTIKLKLPEFLNL 164
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007888.1 (pep scaffold:Pmarinus_7.0:GL477427:174304:193458:1 gene:ENSPMAG00000007039.1 transcript:ENSPMAT00000007888.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.3445 bits (207), Expect = 2.896e-19
Identity = 47/154 (30.52%), Postives = 80/154 (51.95%), Query Frame = 1 
Query:  130 INQYELQQAL--------SNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKF-DRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLV 564
            I+  ELQ  L        S  T   F  E  R M+ + D+D   ++   EF  LWK + +WQ  F  YD D +GT++  E+++AL + G+RL++    ++  ++ D +   TI FD+++   V L+T+   F+  + D +  I +N  QFL + 
Sbjct:  405 ISAKELQSILNRVVSKLHSTVTTDGFGLEACRSMVSLMDKDGTAKLGVKEFNFLWKKIKNWQQIFLEYDTDSTGTMNSMEMRLALEAAGFRLNEKLNQIVTTRYADGENGITIDFDNYVCCLVRLETMFRTFQALEKDGNEKINLNLPQFLHVT 558
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000846.1 (pep scaffold:Pmarinus_7.0:GL481444:15725:20048:-1 gene:ENSPMAG00000000771.1 transcript:ENSPMAT00000000846.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.7221 bits (195), Expect = 5.567e-19
Identity = 38/123 (30.89%), Postives = 68/123 (55.28%), Query Frame = 1 
Query:  181 FNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQ 549
            F+ +  R M+ + DRD +G++   EF  LW+ +  WQ  FR +D D SG ++  E ++AL   G+RL+D     +  ++  +  G I FD+++   V L+T+   F+  + D DG I++   +
Sbjct:   46 FSLDACRNMVSLMDRDGSGKLGIKEFNFLWQRIKSWQQIFRQFDMDHSGNMNGYEFRLALAEAGFRLNDQLTQTITMRYMEEN-GVIDFDNYLCCLVRLETMFRIFQALNKDGDGTIKLKLPE 167
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Yeast
Match: PEF1 (Penta-EF-hand protein; required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2; binds to Sec31p and modulates COPII coat assembly [Source:SGD;Acc:S000003290])

HSP 1 Score: 69.707 bits (169), Expect = 1.213e-14
Identity = 49/160 (30.63%), Postives = 75/160 (46.88%), Query Frame = 1 
Query:   91 QVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGY----RLSDNFFNLLIRKFDRQGRGT-IAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFL 555
            Q+F   D      +   ELQ  L N   + F   +V  +I +F     G ++  EF  L+K V  W+  +   D +GS TI  +E   +L   GY     +S+  F+      +R G G  + FD F+++ V L  LT  FR FDT+ +G   I Y+ F+
Sbjct:  164 QLFHNHDVKGKNRLTAEELQNLLQNDDNSHFCISSVDALINLFGASRFGTVNQAEFIALYKRVKSWRKVYVDNDINGSLTISVSEFHNSLQELGYLIPFEVSEKTFDQYAEFINRNGTGKELKFDKFVEALVWLMRLTKLFRKFDTNQEGIATIQYKDFI 323
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 56.9954 bits (136), Expect = 4.649e-11
Identity = 40/129 (31.01%), Postives = 59/129 (45.74%), Query Frame = 1 
Query:   91 QVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWK-------YVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDF 456
            + F   DKD +G+I+  EL   + +   +P   E   LM    D D N QI F+EF  L            +    F+ +D++G G I   ELK  LTS G +L+D   + ++R+    G G I    F
Sbjct:   15 EAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLM-NEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEINIQQF 141
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 43.8986 bits (102), Expect = 3.597e-6
Identity = 28/90 (31.11%), Postives = 43/90 (47.78%), Query Frame = 1 
Query:  292 NTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDF-------IQSCVSLQTLTNAFRGFDTDLDGWIQIN 540
              F  +D +  G +D +ELK+A+ + G+ L       LI ++D +GR  + +DDF       I     L  +  AF+ FD D  G I I 
Sbjct:   27 EAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIK 116
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Nematostella
Match: EDO45947 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRG9])

HSP 1 Score: 265.003 bits (676), Expect = 4.698e-91
Identity = 127/179 (70.95%), Postives = 150/179 (83.80%), Query Frame = 1 
Query:   49 MAYY--QPNN--DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            MAY+  QP    DPN+L  +FQ+VDKDRSG+I+  ELQQALSNGTWTPFNPETVRLMIGMFDRDNNG I+F EF  LWKY+ DWQ TFR+YDRD SGTID+NEL+ ALTSFGYRLSD F+++LI+KFDR GRG + FDDFIQ CV +Q LTNAF+ +D + +GWI INYEQFL+LV+SL
Sbjct:    1 MAYHYQQPQGGYDPNYLSGIFQRVDKDRSGSISSNELQQALSNGTWTPFNPETVRLMIGMFDRDNNGTINFQEFSSLWKYITDWQTTFRNYDRDSSGTIDKNELQNALTSFGYRLSDKFYSILIKKFDRSGRGVVNFDDFIQCCVVIQMLTNAFQAYDNNRNGWISINYEQFLSLVFSL 179
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Nematostella
Match: EDO46008 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRG8])

HSP 1 Score: 231.106 bits (588), Expect = 1.107e-77
Identity = 113/177 (63.84%), Postives = 132/177 (74.58%), Query Frame = 1 
Query:   49 MAYYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            MAY Q   D NWLY +F ++D D++GAI   ELQ+ALSNG+W PFNPETVRL +GMFDRDN+G I FNEF  LW+YV DWQ  FRSYD D SGTID +ELK AL SFG+RLSD  +++LI KFDR G G I FDDFIQ CV LQ LTN+F   D    G I I YEQFLT+V+SLN+
Sbjct:    1 MAYNQVPIDRNWLYGIFTRIDADKNGAITGDELQKALSNGSWAPFNPETVRLFMGMFDRDNSGTIEFNEFYSLWQYVTDWQKAFRSYDTDNSGTIDIDELKTALRSFGFRLSDRIYSMLITKFDRTGNGAIRFDDFIQCCVVLQILTNSFSHHDFARRGVITIQYEQFLTMVFSLNL 177
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Nematostella
Match: EDO38075 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE04])

HSP 1 Score: 176.792 bits (447), Expect = 1.590e-56
Identity = 83/152 (54.61%), Postives = 105/152 (69.08%), Query Frame = 1 
Query:  106 VDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTL 561
            VD+DR+G I   EL+ AL N  W+ FN ET R+MIGMFD+D +G I   EF  LW+Y+  W+N F S+DRD SGTID  EL  A ++FGYRLS  F NL ++KFDR  R T+ FDDFIQ CV L++LT+AFR +D    G + I+YEQ  TL
Sbjct:    2 VDQDRTGKITASELRAALVNSNWSQFNEETCRMMIGMFDKDGSGTIDIYEFAALWQYIQQWKNCFDSFDRDRSGTIDAGELNTAFSTFGYRLSPQFCNLCVQKFDRSDRNTMKFDDFIQCCVMLKSLTDAFRKYDVQQSGQVTISYEQVSTL 153

HSP 2 Score: 44.2838 bits (103), Expect = 7.352e-6
Identity = 25/80 (31.25%), Postives = 38/80 (47.50%), Query Frame = 1 
Query:   94 VFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTI 333
             F   D+DRSG I+  EL  A S   +   +P+   L +  FDR +   + F++F Q    +    + FR YD   SG +
Sbjct:   65 CFDSFDRDRSGTIDAGELNTAFSTFGY-RLSPQFCNLCVQKFDRSDRNTMKFDDFIQCCVMLKSLTDAFRKYDVQQSGQV 143
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Nematostella
Match: EDO42846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0B4])

HSP 1 Score: 175.637 bits (444), Expect = 4.272e-56
Identity = 84/160 (52.50%), Postives = 110/160 (68.75%), Query Frame = 1 
Query:   85 LYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLV 564
            L+  F  VD+DRSGAI+  EL+QAL N  W+ FN ET RLMIG+FD D +G I+F EFQQLW Y+  W+ +F  YD D SG I   EL  A    G+R+S  F +L++ KFDR  R ++ FDDFIQ CV ++ LT+AFR  DT+++G IQINYE F+ +V
Sbjct:    3 LWNWFIAVDRDRSGAISSDELEQALMNNNWSRFNQETCRLMIGLFDHDQSGTINFQEFQQLWSYIQQWKGSFDRYDTDRSGNISGQELHTAFAEMGFRVSPQFISLVLIKFDRAARSSLKFDDFIQCCVMIRMLTDAFRARDTNMNGVIQINYEDFMQMV 162
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Nematostella
Match: EDO25978 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TD75])

HSP 1 Score: 115.161 bits (287), Expect = 5.042e-33
Identity = 60/124 (48.39%), Postives = 77/124 (62.10%), Query Frame = 1 
Query:   85 LYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISF-NEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDD 453
            L+  F  VD+DRSGAI+  EL+QAL N  W+ FN ET RLMIG+      G  S  +EFQQLW Y+  W+ +F  YD D SG I   EL  AL   G+R+S  F +L++ KFDR  R ++ FDD
Sbjct:    1 LWNWFIAVDRDRSGAISSDELEQALMNNNWSRFNQETCRLMIGIKKNTFTGIASVPSEFQQLWSYIQQWKGSFDRYDTDRSGNISGQELHTALAEMGFRVSPQFISLVLIKFDRAARSSLKFDD 124
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Medaka
Match: pdcd6 (programmed cell death 6 [Source:NCBI gene;Acc:101159541])

HSP 1 Score: 238.81 bits (608), Expect = 2.506e-80
Identity = 113/184 (61.41%), Postives = 142/184 (77.17%), Query Frame = 1 
Query:   49 MAYYQPNNDP---------NWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            MAY+ P   P         ++L+ +FQ+VDKDRSG I+  ELQQALSNGTWTPFNP TVR +I MFDR+N G ++FNEF  +WKY+ DWQN FR+YDRD SG ID+NELK ALT FGYRLSD F+  LI KFDRQ +G +AFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+++
Sbjct:    1 MAYHSPYRAPPHINAPPDQSFLWNIFQRVDKDRSGVISDSELQQALSNGTWTPFNPVTVRSIISMFDRENKGGVNFNEFAGVWKYITDWQNIFRTYDRDNSGFIDKNELKQALTGFGYRLSDQFYGTLIDKFDRQRKGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWIQVSYEQYLSMVFNV 184
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Medaka
Match: pdcd6 (programmed cell death 6 [Source:NCBI gene;Acc:101159541])

HSP 1 Score: 214.157 bits (544), Expect = 1.510e-70
Identity = 106/184 (57.61%), Postives = 136/184 (73.91%), Query Frame = 1 
Query:   49 MAYYQPNNDP---------NWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            MAY+ P   P         ++L+ +FQ+VDKDRSG I+  ELQQALSNGT  P +   + LM  MFDR+N G ++FNEF  +WKY+ DWQN FR+YDRD SG ID+NELK ALT FGYRLSD F+  LI KFDRQ +G +AFDDFIQ C+ LQ LT+ FR +DTD DGWIQ++YEQ+L++V+++
Sbjct:    1 MAYHSPYRAPPHINAPPDQSFLWNIFQRVDKDRSGVISDSELQQALSNGT--PLSVTNITLM-SMFDRENKGGVNFNEFAGVWKYITDWQNIFRTYDRDNSGFIDKNELKQALTGFGYRLSDQFYGTLIDKFDRQRKGQVAFDDFIQCCIVLQRLTDVFRRYDTDQDGWIQVSYEQYLSMVFNV 181
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Medaka
Match: pef1 (penta-EF-hand domain containing 1 [Source:NCBI gene;Acc:101155780])

HSP 1 Score: 146.362 bits (368), Expect = 5.441e-43
Identity = 78/173 (45.09%), Postives = 103/173 (59.54%), Query Frame = 1 
Query:   52 AYYQPNNDPNW---LYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQG-RGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLT 558
            +++Q N  P      +Q FQ VD DRSG IN  EL+QAL N  W+ FN ET  +MI MFDR  +G+I    F  LW Y+  W+  F+ YDRDGSG+I   EL  AL   GY LS  F   ++++F  +G R  I  D FIQ C  LQT+T  FR  DT + G ++++YE FL+
Sbjct:   84 SFFQTNTPPGVNPEAFQWFQSVDTDRSGFINHSELKQALVNSNWSTFNDETCLMMINMFDRTRSGRIDLYGFSALWDYMQRWRALFQQYDRDGSGSISGTELHQALVQMGYNLSPQFSEAVVQRFTIRGVRPGIQLDRFIQVCTQLQTMTQQFREKDTSMTGNVRLSYEDFLS 256
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Medaka
Match: ENSORLT00000041617.1 (sorcin-like [Source:NCBI gene;Acc:101157587])

HSP 1 Score: 124.79 bits (312), Expect = 1.768e-35
Identity = 70/171 (40.94%), Postives = 99/171 (57.89%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            DP  LY  F  V   + G I   ELQ  L+    +GT+ PF+ ET RLMI M DRD +G + FNEF+ LW+ +  W+ TF S+DRD SGTI+  EL+ A+ + GY LS    N ++ ++   G+  I FDDF+   V L+ LT+ FR  DT+  G     Y+ F+ +  S+
Sbjct:   20 DP--LYGYFSAV-AGQDGQITADELQACLTQSGISGTYKPFSLETCRLMINMLDRDMSGTMGFNEFRDLWQALNGWKGTFVSFDRDQSGTIEGQELQQAIRTLGYNLSPQAMNCIMMRYSNHGK--IPFDDFVSCSVKLRALTDQFRRRDTNQSGGALFQYDDFIQVTMSV 185
[Close]
BLAST of Programmed cell death protein 6 vs. Ensembl Medaka
Match: zgc:92027 (sorcin [Source:NCBI gene;Acc:101162581])

HSP 1 Score: 122.865 bits (307), Expect = 2.873e-34
Identity = 62/172 (36.05%), Postives = 104/172 (60.47%), Query Frame = 1 
Query:   70 NDPNWLYQVFQKVDKDRSGAINQYELQQALS----NGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSL 573
            NDP W Y  F  +   + G ++  ELQ+ L+     G+++PF+ E+ R+MI M DRD  G++ FNEF++L+  +  W+  F  +D+D SGT++  EL  A+ + G+R+S    N++I+++++ GR  I FDD++  CV L+TLT  FR  DT   G +   Y+ F+    ++
Sbjct:   57 NDPMWGY--FTAI-AGQDGEVDAEELQKCLTQAGFTGSYSPFSLESCRIMIAMLDRDYTGKMGFNEFKELFVALNGWKQNFMMFDQDRSGTVEPRELSQAINAMGFRVSPQALNVIIQRYNKGGR--IFFDDYVACCVKLRTLTENFRRRDTMQQGSVTFQYDDFILCSMAV 223
[Close]
BLAST of Programmed cell death protein 6 vs. Planmine SMEST
Match: SMESG000036586.1 (SMESG000036586.1)

HSP 1 Score: 360.533 bits (924), Expect = 1.189e-128
Identity = 176/177 (99.44%), Postives = 176/177 (99.44%), Query Frame = 1 
Query:   49 MAYYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            MAYYQPN DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV
Sbjct:    1 MAYYQPNTDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 177
[Close]
BLAST of Programmed cell death protein 6 vs. Planmine SMEST
Match: SMESG000068256.1 (SMESG000068256.1)

HSP 1 Score: 261.922 bits (668), Expect = 1.284e-89
Identity = 128/173 (73.99%), Postives = 146/173 (84.39%), Query Frame = 1 
Query:   67 NNDPN--WLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            NN PN  +L ++F KVD+D++G I+Q ELQ ALSNGTWTPFNPETVRLMIGMFDRDNNGQI F+EF+ LW Y+  WQ TF+ +D D SG+ID +ELK ALTSFGYRLSDNFF LLIRKFDRQ  GT+AFDDFIQ+CVSLQTLTN FR +DTDLDG I I YEQFLTLVYSLN+
Sbjct:    3 NNRPNSNYLREMFNKVDRDKNGQISQQELQSALSNGTWTPFNPETVRLMIGMFDRDNNGQIGFDEFESLWTYIIHWQQTFQRFDLDNSGSIDFHELKNALTSFGYRLSDNFFRLLIRKFDRQAHGTVAFDDFIQACVSLQTLTNGFRHYDTDLDGIITIGYEQFLTLVYSLNI 175
[Close]
BLAST of Programmed cell death protein 6 vs. Planmine SMEST
Match: SMESG000016908.1 (SMESG000016908.1)

HSP 1 Score: 218.394 bits (555), Expect = 1.410e-72
Identity = 108/169 (63.91%), Postives = 125/169 (73.96%), Query Frame = 1 
Query:   73 DPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFLTLVYSLNV 579
            DP    Q+FQ VDKDRSG IN  ELQQALSNGTWTPFN   VR MIGMFD+D +G +  NEFQQLWK+VGDWQ  F+SYDRD SG ID+NEL  AL+ FGYRL+  FF  L+ KFDRQ RG IAFDDF+  C+ LQTLTN+FR  D +  G IQ+ YEQFL L  + N+
Sbjct:    2 DPT---QIFQSVDKDRSGQINDVELQQALSNGTWTPFNISLVRTMIGMFDQDRSGTVGLNEFQQLWKFVGDWQRVFQSYDRDRSGFIDQNELMTALSQFGYRLTPQFFQTLMWKFDRQRRGQIAFDDFVHCCIVLQTLTNSFRNLDRNRSGVIQLGYEQFLHLFLTTNI 167
[Close]
BLAST of Programmed cell death protein 6 vs. Planmine SMEST
Match: SMESG000017238.1 (SMESG000017238.1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.802e-20
Identity = 46/131 (35.11%), Postives = 75/131 (57.25%), Query Frame = 1 
Query:  181 FNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFRGFDTDLDGWIQINYEQFL-TLVYS 570
            F  +T R M+ M D D +G++ F EFQ +W  +  W+  F+  D+DGSG++   EL+  L + G+R+S+  F  L+ +F  +  GTI FDDF+  CV L+T+   F+    D      I+ + F+ + +YS
Sbjct:  640 FTIDTCRSMVAMMDIDLSGRLGFEEFQVMWLDLKLWKTVFKKEDKDGSGSLSSYELRTLLNAIGFRVSNKIFTNLVVRFATKD-GTIEFDDFVHCCVRLKTVFQTFKAQKKDAHNNAIIDQDTFIQSSIYS 769
[Close]
BLAST of Programmed cell death protein 6 vs. Planmine SMEST
Match: SMESG000039299.1 (SMESG000039299.1)

HSP 1 Score: 88.9669 bits (219), Expect = 2.990e-20
Identity = 45/129 (34.88%), Postives = 75/129 (58.14%), Query Frame = 1 
Query:  130 INQYELQQALSNG-----TWTPFNPETVRLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNELKMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAFR 501
            I+ YELQ  L+        +  F+ ET + M+ M D D +G++ F+EF+ LW  +  W+  F+ +D+D SG  +  EL++ L S G+RLS+   N L+ +F  +  G + FDD+I  CV L+T+   ++
Sbjct:  620 IDAYELQDILNTAFKKDFKFDGFSIETSKSMVAMMDYDQSGKLGFDEFKVLWTDLRLWKEAFKKFDQDKSGNFNSYELRLCLNSVGFRLSNKILNSLVMRFANK-EGLVLFDDYILCCVRLKTIFETYK 747
The following BLAST results are available for this feature:
BLAST of Programmed cell death protein 6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PDCD61.315e-8167.07programmed cell death 6 [Source:HGNC Symbol;Acc:HG... [more]
PDCD65.857e-7966.47programmed cell death 6 [Source:HGNC Symbol;Acc:HG... [more]
PDCD65.082e-5665.83programmed cell death 6 [Source:HGNC Symbol;Acc:HG... [more]
PEF18.214e-4345.29penta-EF-hand domain containing 1 [Source:HGNC Sym... [more]
SRI8.390e-3840.23sorcin [Source:HGNC Symbol;Acc:HGNC:11292][more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
M04F3.44.843e-7562.71pep chromosome:WBcel235:I:4771348:4773070:-1 gene:... [more]
M04F3.44.843e-7562.71pep chromosome:WBcel235:I:4771348:4773673:-1 gene:... [more]
M04F3.44.843e-7562.71pep chromosome:WBcel235:I:4771600:4773026:-1 gene:... [more]
cal-45.729e-1431.03CALmodulin related genes [Source:UniProtKB/TrEMBL... [more]
cal-41.105e-1331.03CALmodulin related genes [Source:UniProtKB/TrEMBL... [more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Alg-25.882e-8366.85gene:FBgn0086378 transcript:FBtr0301810[more]
CG177651.489e-4245.51gene:FBgn0033529 transcript:FBtr0088274[more]
CalpB7.443e-1934.13gene:FBgn0025866 transcript:FBtr0076343[more]
CalpB7.443e-1934.13gene:FBgn0025866 transcript:FBtr0304675[more]
CalpA2.589e-1732.54gene:FBgn0012051 transcript:FBtr0340532[more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pdcd61.678e-8163.59programmed cell death 6 [Source:ZFIN;Acc:ZDB-GENE-... [more]
sri2.298e-3739.08sorcin [Source:ZFIN;Acc:ZDB-GENE-040426-1356][more]
pef15.520e-3741.57penta-EF-hand domain containing 1 [Source:NCBI gen... [more]
GCA5.125e-3635.63zgc:92027 [Source:ZFIN;Acc:ZDB-GENE-040930-3][more]
GCA4.974e-3435.76zgc:92027 [Source:ZFIN;Acc:ZDB-GENE-040930-3][more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pdcd62.221e-8062.84programmed cell death 6 [Source:NCBI gene;Acc:4933... [more]
pdcd62.051e-7866.67programmed cell death 6 [Source:NCBI gene;Acc:4933... [more]
etfdh3.137e-4143.53electron transfer flavoprotein dehydrogenase [Sour... [more]
etfdh3.229e-4143.53electron transfer flavoprotein dehydrogenase [Sour... [more]
sri7.842e-3539.18sorcin [Source:NCBI gene;Acc:549421][more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pdcd61.778e-8167.07programmed cell death 6 [Source:MGI Symbol;Acc:MGI... [more]
Pdcd68.549e-7966.47programmed cell death 6 [Source:MGI Symbol;Acc:MGI... [more]
Pef12.343e-4244.71penta-EF hand domain containing 1 [Source:MGI Symb... [more]
Pef12.343e-4244.71penta-EF hand domain containing 1 [Source:MGI Symb... [more]
Sri1.750e-3739.08sorcin [Source:MGI Symbol;Acc:MGI:98419][more]
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BLAST of Programmed cell death protein 6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O75340|PDCD6_HUMAN6.315e-8167.07Programmed cell death protein 6 OS=Homo sapiens OX... [more]
sp|P12815|PDCD6_MOUSE1.244e-8067.07Programmed cell death protein 6 OS=Mus musculus OX... [more]
sp|G3V7W1|PDCD6_RAT3.401e-8066.47Programmed cell death protein 6 OS=Rattus norvegic... [more]
sp|Q94743|SORCN_SCHJA2.696e-5956.29Sorcin OS=Schistosoma japonicum OX=6182 PE=2 SV=1[more]
sp|Q9UBV8|PEF1_HUMAN3.945e-4245.29Peflin OS=Homo sapiens OX=9606 GN=PEF1 PE=1 SV=1[more]
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BLAST of Programmed cell death protein 6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7NIJ81.692e-9276.05Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A1S3HVK31.180e-9175.71programmed cell death protein 6-like isoform X3 OS... [more]
A0A194APN41.411e-9079.04Putative programmed cell death protein 6-like prot... [more]
A0A3S1BKU51.670e-9076.47Uncharacterized protein OS=Elysia chlorotica OX=18... [more]
K1QIZ72.701e-9078.44Programmed cell death protein 6 OS=Crassostrea gig... [more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pdcd61.168e-8165.32programmed cell death 6 [Source:NCBI gene;Acc:1030... [more]
pdcd61.517e-7159.43programmed cell death 6 [Source:NCBI gene;Acc:1030... [more]
sri2.126e-3840.59sorcin-like [Source:NCBI gene;Acc:103031467][more]
pef11.186e-3741.18penta-EF-hand domain containing 1 [Source:NCBI gen... [more]
zgc:920277.341e-3636.78grancalcin-like [Source:NCBI gene;Acc:103040268][more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:920271.397e-4040.80grancalcin [Source:HGNC Symbol;Acc:HGNC:15990][more]
capn3a4.247e-2134.11calpain 3a, (p94) [Source:ZFIN;Acc:ZDB-GENE-040912... [more]
ENSPMAT00000000845.11.106e-2032.28pep scaffold:Pmarinus_7.0:GL481444:15049:20027:-1 ... [more]
ENSPMAT00000007888.12.896e-1930.52pep scaffold:Pmarinus_7.0:GL477427:174304:193458:1... [more]
ENSPMAT00000000846.15.567e-1930.89pep scaffold:Pmarinus_7.0:GL481444:15725:20048:-1 ... [more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
PEF11.213e-1430.63Penta-EF-hand protein; required for polar bud grow... [more]
CMD14.649e-1131.01Calmodulin; Ca2+ binding protein that regulates Ca... [more]
CDC313.597e-631.11Calcium-binding component of the spindle pole body... [more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO459474.698e-9170.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO460081.107e-7763.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO380751.590e-5654.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO428464.272e-5652.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO259785.042e-3348.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Programmed cell death protein 6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pdcd62.506e-8061.41programmed cell death 6 [Source:NCBI gene;Acc:1011... [more]
pdcd61.510e-7057.61programmed cell death 6 [Source:NCBI gene;Acc:1011... [more]
pef15.441e-4345.09penta-EF-hand domain containing 1 [Source:NCBI gen... [more]
ENSORLT00000041617.11.768e-3540.94sorcin-like [Source:NCBI gene;Acc:101157587][more]
zgc:920272.873e-3436.05sorcin [Source:NCBI gene;Acc:101162581][more]
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BLAST of Programmed cell death protein 6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000036586.11.189e-12899.44SMESG000036586.1[more]
SMESG000068256.11.284e-8973.99SMESG000068256.1[more]
SMESG000016908.11.410e-7263.91SMESG000016908.1[more]
SMESG000017238.11.802e-2035.11SMESG000017238.1[more]
SMESG000039299.12.990e-2034.88SMESG000039299.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016839 ID=SMED30016839|Name=Programmed cell death protein 6|organism=Schmidtea mediterranea sexual|type=transcript|length=673bp
CTTGTTTATATTTTCAAAGATAAATTTATTTAGTTGTAGAAATTTCGAAT
GGCATATTATCAACCAAATAATGACCCCAATTGGTTGTATCAAGTATTTC
AGAAAGTAGATAAAGATCGAAGTGGAGCTATAAATCAGTATGAACTTCAA
CAAGCTTTATCAAATGGAACCTGGACACCATTTAATCCTGAAACTGTCAG
ACTTATGATAGGAATGTTTGATAGAGATAATAATGGCCAAATTTCTTTTA
ATGAATTTCAACAATTGTGGAAGTACGTCGGTGATTGGCAAAACACCTTT
CGTTCATACGATCGTGATGGATCAGGTACTATTGACAGAAATGAATTGAA
AATGGCACTTACATCATTTGGCTATCGGTTGTCTGATAATTTTTTTAATT
TGTTGATCAGAAAGTTCGATCGTCAAGGCCGAGGAACAATTGCATTTGAC
GATTTTATTCAGTCATGTGTTTCGCTGCAGACACTAACTAATGCTTTCAG
AGGATTTGATACTGATCTTGATGGTTGGATTCAAATTAACTACGAACAGT
TCCTGACACTTGTTTACAGTCTCAACGTTTGATTGGTTAGTTATCCGGGC
AAATGAAATTGAACATTAATGGATTTAAATTCCTAAAATTTTTATATAAA
TTTAGTCGTGCTTTGAAAAAAAA
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protein sequence of SMED30016839-orf-1

>SMED30016839-orf-1 ID=SMED30016839-orf-1|Name=SMED30016839-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=178bp
MAYYQPNNDPNWLYQVFQKVDKDRSGAINQYELQQALSNGTWTPFNPETV
RLMIGMFDRDNNGQISFNEFQQLWKYVGDWQNTFRSYDRDGSGTIDRNEL
KMALTSFGYRLSDNFFNLLIRKFDRQGRGTIAFDDFIQSCVSLQTLTNAF
RGFDTDLDGWIQINYEQFLTLVYSLNV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR039647EF_hand_pair_protein_CML-like
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002048EF-hand domainSMARTSM00054efh_1coord: 49..77
e-value: 0.001
score: 28.3
coord: 79..107
e-value: 4.9E-6
score: 36.0
coord: 145..175
e-value: 30.0
score: 5.8
coord: 12..40
e-value: 0.36
score: 19.9
coord: 115..143
e-value: 37.0
score: 5.1
IPR002048EF-hand domainPFAMPF13499EF-hand_7coord: 82..138
e-value: 2.9E-9
score: 37.2
coord: 12..74
e-value: 2.3E-13
score: 50.4
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 45..73
score: 7.958
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 111..146
score: 7.54
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 75..110
score: 14.569
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 8..43
score: 10.245
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 8..176
e-value: 4.9E-57
score: 194.2
NoneNo IPR availablePANTHERPTHR10891:SF764coord: 2..175
NoneNo IPR availableCDDcd16183EFh_PEF_ALG-2coord: 12..176
e-value: 4.70869E-110
score: 308.8
IPR039647EF-hand domain pair protein CML-likePANTHERPTHR10891EF-HAND CALCIUM-BINDING DOMAIN CONTAINING PROTEINcoord: 2..175
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 88..100
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 21..33
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 6..172