Cathepsin L

Overview


Name	Cathepsin L
Smed ID	SMED30016824
Length (bp)	375

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Cathepsin L (SMED30016824) t-SNE clustered cells

Violin plots show distribution of expression levels for Cathepsin L (SMED30016824) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016824

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 35

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30016824	h1SMcG0007334	Contig1337	GPL15192	PMID:23079596 Forsthoefel et al., 2012
epidermis	SMED30016824	h1SMcG0007334	Contig1337	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30016824	h1SMcG0007334	Contig1337	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30016824	h1SMcG0007334	Contig7289	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30016824	h1SMcG0007334	Contig7289	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
non-ciliated neuron	SMED30016824	h1SMcG0007335	dd_Smed_v4_73979_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30016824	h1SMcG0007334	dd_Smed_v4_73979_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
copulatory apparatus	SMED30016824	h1SMcG0007334	PL030013A20C10	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017
copulatory apparatus	SMED30016824	h1SMcG0007334	PL03018A1A09	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig12527	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig12527	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig10350	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig10350	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
copulatory apparatus	SMED30016824	h1SMcG0007334	Contig1344	GPL15192	PMID:28434803 Rouhana et al., 2017
copulatory apparatus	SMED30016824	h1SMcG0007334	Contig1337	GPL15192	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig8763	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig8763	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig9364	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig9364	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig7289	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig7289	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig18253	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig18253	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig26832	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig26832	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig19864	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig19864	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig32941	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig32941	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig6059	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig6059	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig4189	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig4189	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig32104	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016824	h1SMcG0007334	Contig32104	newmark_ests	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Cathepsin L vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 140.969 bits (354), Expect = 2.023e-41
Identity = 68/124 (54.84%), Postives = 84/124 (67.74%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y     VAN T FTV+ PG E  L  AVATVGP+SV +DA H  FQ YK+GIY  P CS   L+H VL+VGYG    + N   +W+VKNSWGP+WG  GY+ ++KDK+N CGIA+ A+YP V
Sbjct:  211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334

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Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y     VAN T FTV+ PG E  L  AVATVGP+SV +DA H  FQ YK+GIY  P CS   L+H VL+VGYG    + N   +W+VKNSWGP+WG  GY+ ++KDK+N CGIA+ A+YP V
Sbjct:  211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334

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BLAST of Cathepsin L vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 127.872 bits (320), Expect = 2.419e-36
Identity = 67/124 (54.03%), Postives = 80/124 (64.52%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG--SLNGDN--FWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+    VAN T F  I P  E  L  AVATVGP+SV IDA H  F  YK GIY  P CS   ++H VL+VGYG  S   DN  +W+VKNSWG +WG+ GY+ M+KD+ N CGIAS A+YP V
Sbjct:  211 CKYNPKYSVANDTGFVDI-PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333

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Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG--SLNGDN--FWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+    VAN T F  I P  E  L  AVATVGP+SV IDA H  F  YK GIY  P CS   ++H VL+VGYG  S   DN  +W+VKNSWG +WG+ GY+ M+KD+ N CGIAS A+YP V
Sbjct:  211 CKYNPKYSVANDTGFVDI-PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333

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BLAST of Cathepsin L vs. Ensembl Human
Match: CTSS (cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545])

HSP 1 Score: 126.331 bits (316), Expect = 3.431e-36
Identity = 60/121 (49.59%), Postives = 79/121 (65.29%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC YD     A  + +T +  G E  L  AVA  GPVSV +DA HP F  Y++G+Y  P C+   +NH VL+VGYG LNG  +W+VKNSWG ++G EGYI M+++K N CGIAS  +YP +
Sbjct:  162 KCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 281

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BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 120.168 bits (300), Expect = 3.340e-35
Identity = 58/123 (47.15%), Postives = 84/123 (68.29%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS--LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC ++K  V A+   +     G+E  L  AVAT GP+S+ IDA H  FQ YK G+Y + +CS   L+H VL+VGYG+   +GD +WIVKNSWG  WG +GYI ++++++N CG+A+ A+YP+V
Sbjct:   77 KCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198

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Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS--LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC ++K  V A+   +     G+E  L  AVAT GP+S+ IDA H  FQ YK G+Y + +CS   L+H VL+VGYG+   +GD +WIVKNSWG  WG +GYI ++++++N CG+A+ A+YP+V
Sbjct:   77 KCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198

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BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 121.324 bits (303), Expect = 3.022e-34
Identity = 58/123 (47.15%), Postives = 84/123 (68.29%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS--LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC ++K  V A+   +     G+E  L  AVAT GP+S+ IDA H  FQ YK G+Y + +CS   L+H VL+VGYG+   +GD +WIVKNSWG  WG +GYI ++++++N CG+A+ A+YP+V
Sbjct:  216 KCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337

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BLAST of Cathepsin L vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 81.6481 bits (200), Expect = 4.397e-19
Identity = 44/116 (37.93%), Postives = 67/116 (57.76%), Query Frame = 1

Query:   22 KVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPK--CSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            K +A + + +V  P +E ++   + T GP+S+ ++A+    Q Y+ G+ +  K  C    LNH VLIVGYG      +WIVKNSWGP+WG  GY  + + K N CG+  +A   +V
Sbjct:  364 KDIAVYINGSVELPHDEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMATSALV 476

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BLAST of Cathepsin L vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 81.6481 bits (200), Expect = 4.397e-19
Identity = 44/116 (37.93%), Postives = 67/116 (57.76%), Query Frame = 1

Query:   22 KVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPK--CSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            K +A + + +V  P +E ++   + T GP+S+ ++A+    Q Y+ G+ +  K  C    LNH VLIVGYG      +WIVKNSWGP+WG  GY  + + K N CG+  +A   +V
Sbjct:  364 KDIAVYINGSVELPHDEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMATSALV 476

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BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0304021)

HSP 1 Score: 135.191 bits (339), Expect = 2.632e-40
Identity = 63/121 (52.07%), Postives = 86/121 (71.07%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS-LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C ++K  V A    FT I  G+E  +A AVATVGPVSV IDA H  FQ Y  G+YN P+C    L+H VL+VG+G+  +G+++W+VKNSWG  WG +G+I M ++K+NQCGIAS ++YP+V
Sbjct:  129 CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 249

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BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592)

HSP 1 Score: 136.346 bits (342), Expect = 7.271e-40
Identity = 63/121 (52.07%), Postives = 86/121 (71.07%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS-LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C ++K  V A    FT I  G+E  +A AVATVGPVSV IDA H  FQ Y  G+YN P+C    L+H VL+VG+G+  +G+++W+VKNSWG  WG +G+I M ++K+NQCGIAS ++YP+V
Sbjct:  221 CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341

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BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593)

HSP 1 Score: 136.732 bits (343), Expect = 1.033e-39
Identity = 63/121 (52.07%), Postives = 86/121 (71.07%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS-LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C ++K  V A    FT I  G+E  +A AVATVGPVSV IDA H  FQ Y  G+YN P+C    L+H VL+VG+G+  +G+++W+VKNSWG  WG +G+I M ++K+NQCGIAS ++YP+V
Sbjct:  251 CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371

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BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955)

HSP 1 Score: 135.961 bits (341), Expect = 1.047e-39
Identity = 63/121 (52.07%), Postives = 86/121 (71.07%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS-LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C ++K  V A    FT I  G+E  +A AVATVGPVSV IDA H  FQ Y  G+YN P+C    L+H VL+VG+G+  +G+++W+VKNSWG  WG +G+I M ++K+NQCGIAS ++YP+V
Sbjct:  218 CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 338

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BLAST of Cathepsin L vs. Ensembl Fly
Match: CG4847 (gene:FBgn0034229 transcript:FBtr0086934)

HSP 1 Score: 100.138 bits (248), Expect = 8.733e-26
Identity = 52/120 (43.33%), Postives = 71/120 (59.17%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C YD SK  A    F  I P +E  L   VAT+GPV+  ++      ++Y  GIYN+ +C+    NH++L+VGYGS  G ++WIVKNSW   WG +GY  + + K N C IA   +YPVV
Sbjct:  273 CKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGLET-LKNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEECSYPVV 390

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BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 154.451 bits (389), Expect = 8.741e-47
Identity = 71/121 (58.68%), Postives = 91/121 (75.21%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C ++ S V A+ T +  I  G+ES L  AVAT+GP+SV IDA H  FQ Y +G+YN P CS   L+H VL VGYGS NGD++WIVKNSWG DWG++GYILMS++K NQCGIA+ A+YP+V
Sbjct:  214 ECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334

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Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C ++ S V A+ T +  I  G+ES L  AVAT+GP+SV IDA H  FQ Y +G+YN P CS   L+H VL VGYGS NGD++WIVKNSWG DWG++GYILMS++K NQCGIA+ A+YP+V
Sbjct:  214 ECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334

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Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C ++ S V A+ T +  I  G+ES L  AVAT+GP+SV IDA H  FQ Y +G+YN P CS   L+H VL VGYGS NGD++WIVKNSWG DWG++GYILMS++K NQCGIA+ A+YP+V
Sbjct:  214 ECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334

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BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: cts12 (cathepsin 12 [Source:ZFIN;Acc:ZDB-GENE-050208-336])

HSP 1 Score: 134.42 bits (337), Expect = 1.214e-39
Identity = 63/120 (52.50%), Postives = 81/120 (67.50%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+K+  +A  + +  +  GNE  LA AVATVGPVSV IDAD+P F  Y +GIY    C+   LNHAVL+VGYGS  G ++WI+KNSWG  WG  GY+ M ++  N CGIAS A YP++
Sbjct:  162 CFYEKNLAMAGISDYRFVPAGNEQALADAVATVGPVSVAIDADNPSFLFYSSGIYKESNCNPNNLNHAVLVVGYGSEEGTDYWIIKNSWGTGWGEGGYMRMIRNGKNTCGIASYALYPII 281

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BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: cts12 (cathepsin 12 [Source:ZFIN;Acc:ZDB-GENE-050208-336])

HSP 1 Score: 133.65 bits (335), Expect = 1.619e-39
Identity = 63/120 (52.50%), Postives = 81/120 (67.50%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+K+  +A  + +  +  GNE  LA AVATVGPVSV IDAD+P F  Y +GIY    C+   LNHAVL+VGYGS  G ++WI+KNSWG  WG  GY+ M ++  N CGIAS A YP++
Sbjct:  145 CFYEKNLAMAGISDYRFVPAGNEQALADAVATVGPVSVAIDADNPSFLFYSSGIYKESNCNPNNLNHAVLVVGYGSEEGTDYWIIKNSWGTGWGEGGYMRMIRNGKNTCGIASYALYPII 264

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BLAST of Cathepsin L vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 131.724 bits (330), Expect = 6.165e-38
Identity = 65/125 (52.00%), Postives = 84/125 (67.20%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C YD +   AN T F  +  G+E DL  AVA+VGPVSV +DA H  FQ YK+GIY  P+CS   L+H VL+VGYG      +G  +WIVKNSW   WG +GYI ++KD+ N CGIA+ A+YP+V
Sbjct:  211 ECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 335

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BLAST of Cathepsin L vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 132.109 bits (331), Expect = 6.802e-38
Identity = 65/125 (52.00%), Postives = 84/125 (67.20%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C YD +   AN T F  +  G+E DL  AVA+VGPVSV +DA H  FQ YK+GIY  P+CS   L+H VL+VGYG      +G  +WIVKNSW   WG +GYI ++KD+ N CGIA+ A+YP+V
Sbjct:  218 ECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 342

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BLAST of Cathepsin L vs. Ensembl Xenopus
Match: mdk (midkine [Source:Xenbase;Acc:XB-GENE-488502])

HSP 1 Score: 130.568 bits (327), Expect = 1.778e-37
Identity = 61/121 (50.41%), Postives = 82/121 (67.77%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C+Y+ +   A+   F  ++ G+E  L  AV  VGPVSV IDA    FQ Y  G+Y +  C+   +NHAVL VGYG+     +WIVKNSWG DWG +GYILM+++KDN CGI+SLA+YPV+
Sbjct:  211 ECMYNATGKAASCKGFKEVQEGSEKALKKAVGLVGPVSVGIDAGLSSFQFYSKGVYYDKDCNAENINHAVLAVGYGTQKKTKYWIVKNSWGEDWGNKGYILMAREKDNACGISSLASYPVM 331

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BLAST of Cathepsin L vs. Ensembl Xenopus
Match: mdk (midkine [Source:Xenbase;Acc:XB-GENE-488502])

HSP 1 Score: 130.183 bits (326), Expect = 2.909e-37
Identity = 61/121 (50.41%), Postives = 82/121 (67.77%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C+Y+ +   A+   F  ++ G+E  L  AV  VGPVSV IDA    FQ Y  G+Y +  C+   +NHAVL VGYG+     +WIVKNSWG DWG +GYILM+++KDN CGI+SLA+YPV+
Sbjct:  225 ECMYNATGKAASCKGFKEVQEGSEKALKKAVGLVGPVSVGIDAGLSSFQFYSKGVYYDKDCNAENINHAVLAVGYGTQKKTKYWIVKNSWGEDWGNKGYILMAREKDNACGISSLASYPVM 345

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BLAST of Cathepsin L vs. Ensembl Xenopus
Match: harbi1 (harbinger transposase derived 1 [Source:Xenbase;Acc:XB-GENE-6077433])

HSP 1 Score: 125.176 bits (313), Expect = 2.335e-35
Identity = 61/121 (50.41%), Postives = 78/121 (64.46%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC Y+ S   A    F  ++ G+E+ L  AV  VGP+SV IDA    F  YK GIY +  C    +NHAVL VGYG      +WI+KNSWG DWG +GYILM+++K N CGIA+LA+YPV+
Sbjct:  211 KCKYNVSGRAAEIKGFKEVKKGSETALKKAVGLVGPISVGIDAGLDTFFLYKKGIYYDKSCDGDSINHAVLAVGYGKQKKGKYWIIKNSWGEDWGNKGYILMAREKGNACGIANLASYPVM 331

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BLAST of Cathepsin L vs. Ensembl Mouse
Match: 4930486L24Rik (RIKEN cDNA 4930486L24 gene [Source:MGI Symbol;Acc:MGI:1922258])

HSP 1 Score: 135.961 bits (341), Expect = 1.091e-39
Identity = 65/125 (52.00%), Postives = 84/125 (67.20%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC Y      AN   F  I PG E  L  AVA VGP+SV +DA H  FQ Y +GIY  P+C  + LNHAVL+VGYG      +G+++W+VKNSWG +WG++GYI ++KD +N CGIA+LA YP+V
Sbjct:  210 KCRYHAENSAANVRDFVQI-PGREEALMKAVAKVGPISVAVDASHDSFQFYDSGIYYEPQCKRVHLNHAVLVVGYGFEGEESDGNSYWLVKNSWGEEWGMKGYIKIAKDWNNHCGIATLATYPIV 333

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BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 134.035 bits (336), Expect = 7.147e-39
Identity = 66/124 (53.23%), Postives = 82/124 (66.13%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y     VAN T F  I P  E  L  AVATVGP+SV +DA HP  Q Y +GIY  P CS   L+H VL+VGYG      N + +W+VKNSWG +WG+EGYI ++KD+DN CG+A+ A+YPVV
Sbjct:  211 CKYRAEFAVANDTGFVDI-PQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333

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Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y     VAN T F  I P  E  L  AVATVGP+SV +DA HP  Q Y +GIY  P CS   L+H VL+VGYG      N + +W+VKNSWG +WG+EGYI ++KD+DN CG+A+ A+YPVV
Sbjct:  211 CKYRAEFAVANDTGFVDI-PQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333

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BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsll3 (cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917452])

HSP 1 Score: 131.339 bits (329), Expect = 6.879e-38
Identity = 65/121 (53.72%), Postives = 81/121 (66.94%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSL-NGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+     A  T F  ++  +E  L  AVATVGP+SV ID  H  FQ YK G+Y  P CS   L+HAVL+VGYG   +G  +W+VKNSWG DWG+ GYI M+KD++N CGIAS A+YPVV
Sbjct:  212 CRYNPKNSAATVTGFVNVQ-SSEDALMKAVATVGPISVGIDTKHKSFQFYKEGMYYEPDCSSTVLDHAVLVVGYGEESDGRKYWLVKNSWGRDWGMNGYIKMAKDRNNNCGIASDASYPVV 331

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BLAST of Cathepsin L vs. Ensembl Mouse
Match: BC051665 (cDNA sequence BC051665 [Source:MGI Symbol;Acc:MGI:2682300])

HSP 1 Score: 128.642 bits (322), Expect = 7.037e-37
Identity = 64/121 (52.89%), Postives = 79/121 (65.29%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSL-NGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C YD      N T F  + P +E  L  AVA+VGPVSV ID  H  F+ Y+ G Y  P CS   L+HAVL+VGYG   +G  +W+VKNSWG DWG++GYI M+KD+DN CGIA+ A YP V
Sbjct:  211 CRYDPKYSAVNITGFVKV-PLSEDALMNAVASVGPVSVGIDTHHHSFRFYRGGTYYEPDCSSTNLDHAVLVVGYGEESDGRKYWLVKNSWGEDWGMDGYIKMAKDRDNNCGIATYAIYPTV 330

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BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|O60911|CATL2_HUMAN (Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2)

HSP 1 Score: 140.969 bits (354), Expect = 9.717e-41
Identity = 68/124 (54.84%), Postives = 84/124 (67.74%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y     VAN T FTV+ PG E  L  AVATVGP+SV +DA H  FQ YK+GIY  P CS   L+H VL+VGYG    + N   +W+VKNSWGP+WG  GY+ ++KDK+N CGIA+ A+YP V
Sbjct:  211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334

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BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|P09648|CATL1_CHICK (Cathepsin L1 (Fragments) OS=Gallus gallus OX=9031 GN=CTSL PE=1 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 9.987e-40
Identity = 66/120 (55.00%), Postives = 79/120 (65.83%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y      AN T F  I  G+E  L  AVA+VGPVSV IDA H  FQ Y++GIY  P CS   L+H VL+VGYG   G  +WIVKNSWG  WG +GYI M+KD+ N CGIA+ A+YP+V
Sbjct:   99 CRYKAEYNAANDTGFVDIPQGHERALMKAVASVGPVSVAIDAGHSSFQFYQSGIYYEPDCSSEDLDHGVLVVGYGFEGGKKYWIVKNSWGEKWGDKGYIYMAKDRKNHCGIATAASYPLV 218

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BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|Q80UB0|TEST2_MOUSE (Testin-2 OS=Mus musculus OX=10090 PE=2 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 7.634e-39
Identity = 65/125 (52.00%), Postives = 84/125 (67.20%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC Y      AN   F  I PG E  L  AVA VGP+SV +DA H  FQ Y +GIY  P+C  + LNHAVL+VGYG      +G+++W+VKNSWG +WG++GYI ++KD +N CGIA+LA YP+V
Sbjct:  210 KCRYHAENSAANVRDFVQI-PGREEALMKAVAKVGPISVAVDASHDSFQFYDSGIYYEPQCKRVHLNHAVLVVGYGFEGEESDGNSYWLVKNSWGEEWGMKGYIKIAKDWNNHCGIATLATYPIV 333

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BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|Q95029|CATL_DROME (Cathepsin L OS=Drosophila melanogaster OX=7227 GN=Cp1 PE=2 SV=2)

HSP 1 Score: 136.732 bits (343), Expect = 1.035e-38
Identity = 63/121 (52.07%), Postives = 86/121 (71.07%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGS-LNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C ++K  V A    FT I  G+E  +A AVATVGPVSV IDA H  FQ Y  G+YN P+C    L+H VL+VG+G+  +G+++W+VKNSWG  WG +G+I M ++K+NQCGIAS ++YP+V
Sbjct:  251 CHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371

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BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|P06797|CATL1_MOUSE (Cathepsin L1 OS=Mus musculus OX=10090 GN=Ctsl PE=1 SV=2)

HSP 1 Score: 134.035 bits (336), Expect = 4.999e-38
Identity = 66/124 (53.23%), Postives = 82/124 (66.13%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y     VAN T F  I P  E  L  AVATVGP+SV +DA HP  Q Y +GIY  P CS   L+H VL+VGYG      N + +W+VKNSWG +WG+EGYI ++KD+DN CG+A+ A+YPVV
Sbjct:  211 CKYRAEFAVANDTGFVDI-PQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333

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BLAST of Cathepsin L vs. TrEMBL
Match: A0A0N9WMD3 (Cathepsin L OS=Cerebratulus lacteus OX=6221 PE=2 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 1.101e-45
Identity = 69/121 (57.02%), Postives = 92/121 (76.03%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C + KS V A  T F  ++ G+E  L +AV+ VGPVSV IDA HP FQ Y++G+YN P+CS   L+H VL+VGYGS NG ++W+VKNSWGP WGI GYI MS++++NQCGIA+ A+YP+V
Sbjct:  209 RCRFQKSCVAATVTGFVDVQRGSEDALKSAVSEVGPVSVAIDAGHPSFQGYRSGVYNEPRCSQTALDHGVLVVGYGSENGQDYWLVKNSWGPSWGINGYIKMSRNRNNQCGIATQASYPLV 329

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BLAST of Cathepsin L vs. TrEMBL
Match: A0A1I8IYR5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 1.636e-45
Identity = 71/121 (58.68%), Postives = 90/121 (74.38%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C Y +S+V AN T F  I  G+E  L  AVA VGPVSV IDA HP FQHY++G+YN P CS   L+H VL+VGYG+L+G ++W+VKNSW   WG +GYI MS++K+NQCGIAS A+YP V
Sbjct:  231 RCQYQRSRVAANCTGFVDIPQGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACSSQQLDHGVLVVGYGTLSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 351

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BLAST of Cathepsin L vs. TrEMBL
Match: A0A1I8IU52 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 1.818e-45
Identity = 71/121 (58.68%), Postives = 90/121 (74.38%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C Y +S+V AN T F  I  G+E  L  AVA VGPVSV IDA HP FQHY++G+YN P CS   L+H VL+VGYG+L+G ++W+VKNSW   WG +GYI MS++K+NQCGIAS A+YP V
Sbjct:  253 RCQYQRSRVAANCTGFVDIPQGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACSSQQLDHGVLVVGYGTLSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 373

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BLAST of Cathepsin L vs. TrEMBL
Match: A0A267GB11 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008319g1 PE=3 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 1.915e-45
Identity = 71/121 (58.68%), Postives = 90/121 (74.38%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C Y +S+V AN T F  I  G+E  L  AVA VGPVSV IDA HP FQHY++G+YN P CS   L+H VL+VGYG+L+G ++W+VKNSW   WG +GYI MS++K+NQCGIAS A+YP V
Sbjct:  242 RCQYQRSRVAANCTGFVDIPQGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACSSQQLDHGVLVVGYGTLSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 362

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BLAST of Cathepsin L vs. TrEMBL
Match: A0A267DZX3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002369g2 PE=3 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 1.915e-45
Identity = 71/121 (58.68%), Postives = 90/121 (74.38%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C Y +S+V AN T F  I  G+E  L  AVA VGPVSV IDA HP FQHY++G+YN P CS   L+H VL+VGYG+L+G ++W+VKNSW   WG +GYI MS++K+NQCGIAS A+YP V
Sbjct:  242 RCQYQRSRVAANCTGFVDIPQGSEDKLKEAVANVGPVSVAIDASHPSFQHYQSGVYNEPACSSQQLDHGVLVVGYGTLSGSDYWLVKNSWSDMWGEKGYIRMSRNKNNQCGIASTASYPTV 362

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BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023607])

HSP 1 Score: 144.05 bits (362), Expect = 8.248e-43
Identity = 66/120 (55.00%), Postives = 86/120 (71.67%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C +    V A  T F  I  G+E  L  AVAT+GP+SV IDA H  FQ Y++GIYN P CS   L+H VL VGYG+ NG ++W+VKNSWG DWG +GYI MS+++DNQCGIA++++YP+V
Sbjct:  214 CRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSTELDHGVLAVGYGTDNGKDYWLVKNSWGLDWGNKGYIQMSRNEDNQCGIATMSSYPLV 333

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BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000034444.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000030.1:64026:71815:-1 gene:ENSAMXG00000001761.2 transcript:ENSAMXT00000034444.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 142.895 bits (359), Expect = 1.441e-42
Identity = 67/120 (55.83%), Postives = 85/120 (70.83%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C +    V A  T F  I  G+E  L  AVAT+GP+SV IDA H  FQ Y++GIYN P CS   L+H VL VGYG+ +G ++W+VKNSWG DWG +GYI MS++KDNQCGIA+ A+YP+V
Sbjct:  196 CRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSSDLDHGVLAVGYGTDSGKDYWLVKNSWGLDWGNKGYIQMSRNKDNQCGIATAASYPLV 315

[Close]

BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000001797.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000030.1:64026:71812:-1 gene:ENSAMXG00000001761.2 transcript:ENSAMXT00000001797.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 142.124 bits (357), Expect = 1.813e-42
Identity = 67/120 (55.83%), Postives = 85/120 (70.83%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C +    V A  T F  I  G+E  L  AVAT+GP+SV IDA H  FQ Y++GIYN P CS   L+H VL VGYG+ +G ++W+VKNSWG DWG +GYI MS++KDNQCGIA+ A+YP+V
Sbjct:  186 CRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSSDLDHGVLAVGYGTDSGKDYWLVKNSWGLDWGNKGYIQMSRNKDNQCGIATAASYPLV 305

[Close]

BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000042132.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924])

HSP 1 Score: 133.65 bits (335), Expect = 8.078e-39
Identity = 65/120 (54.17%), Postives = 82/120 (68.33%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y    V A  + +  I  G+E  L  AVATVGPVSV ID  H  FQ Y++G+Y+ P CS   L HAVL VGYGS  G ++W+VKNSWG  WG +GYI MS++K+NQCGIA+ A+YP+V
Sbjct:  213 CRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYGSDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYPLV 332

[Close]

BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000048039.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924])

HSP 1 Score: 133.65 bits (335), Expect = 8.078e-39
Identity = 65/120 (54.17%), Postives = 82/120 (68.33%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y    V A  + +  I  G+E  L  AVATVGPVSV ID  H  FQ Y++G+Y+ P CS   L HAVL VGYGS  G ++W+VKNSWG  WG +GYI MS++K+NQCGIA+ A+YP+V
Sbjct:  213 CRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYGSDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYPLV 332

[Close]

BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007755.1 (pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 gene:ENSPMAG00000007008.1 transcript:ENSPMAT00000007755.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 139.043 bits (349), Expect = 1.067e-41
Identity = 63/122 (51.64%), Postives = 89/122 (72.95%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPG-NESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC +  + V    +S+  +EP  NE  L  AVA+VGP+++ ++AD   F+HYK+G++N P C     NHA+L+VGYGSL+G++FWIVKNSWG DWG +GYI M ++KDNQCGIAS+  YP++
Sbjct:  213 KCRFKPANVATKCSSYQFVEPSSNEEVLRQAVASVGPIAIAMNADLDTFKHYKSGLFNEPSCD-KSPNHAMLVVGYGSLSGNDFWIVKNSWGEDWGEKGYIYMIRNKDNQCGIASIGIYPII 333

[Close]

BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 136.346 bits (342), Expect = 1.575e-40
Identity = 67/125 (53.60%), Postives = 83/125 (66.40%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG----SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC YD     AN T F  +  G+E  L  AVA+VGPVSV IDA H  FQ Y++G+Y  P CS   L+H VL+VGYG      NG  +WIVKNSW P WG EGY+LM+++K N CGIA+ A+YP+V
Sbjct:  215 KCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYPLV 339

[Close]

BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 123.635 bits (309), Expect = 5.636e-36
Identity = 65/121 (53.72%), Postives = 80/121 (66.12%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDN-FWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+     A  T F  I  GNE  L  AVA+VGPVS+ IDA    FQ Y +GIY++  CS   L+H VL+VGYG  + +  FWIVKNSWG  WG  GYILM++DKDN CGIA+ A+YP+V
Sbjct:  178 CKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGIYSDSDCSN-NLDHGVLVVGYGVDDDERKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYPLV 297

[Close]

BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.553 bits (301), Expect = 7.995e-35
Identity = 60/121 (49.59%), Postives = 79/121 (65.29%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG-SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C YD     A  T +  I  G+E  L  AVA+VGPVSV IDA    FQ Y +GIY +  CS   ++HAVL+VGYG    G  FW+VKNSWG  WG +GY+ M++D +N CGIA++++YP+V
Sbjct:  174 CKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCSHH-IDHAVLVVGYGVDEMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYPLV 293

[Close]

BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 119.013 bits (297), Expect = 2.586e-34
Identity = 61/121 (50.41%), Postives = 79/121 (65.29%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYG-SLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+     A  T +  I  G+E  L  AVA+VGPVSV IDA    F +Y +GIY +  CS + +NHAVL+VGYG    GD FW+VKNSWG  WG +GY+ M++D +N CGIA  A+YP+V
Sbjct:  176 CKYNPKNKAAEVTGYVEIPEGDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCSHI-INHAVLVVGYGVDEKGDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGIAVTASYPLV 295

[Close]

BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5])

HSP 1 Score: 149.058 bits (375), Expect = 2.255e-45
Identity = 67/121 (55.37%), Postives = 89/121 (73.55%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C +    V A  T +T ++ G+E DL +AVATVGP+SV IDA H  FQ YKTG+Y+ P CS   L+H VL VGYG+ +G ++W+VKNSWG  WG+ GYI MS++KDNQCGIA+ A+YP+V
Sbjct:  205 QCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGAEDGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYPLV 325

[Close]

BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1])

HSP 1 Score: 145.591 bits (366), Expect = 6.763e-44
Identity = 63/121 (52.07%), Postives = 86/121 (71.07%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C + KS + A  T F  +  G+E  L  A  TVGP+SV IDA H  FQ Y +G+YNN  CS   L+H VL+VGYG+  G ++W+VKNSWG  WG+EGYI+MS++K+NQCG+A+ A+YP+V
Sbjct:  210 RCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYNNAGCSSTSLDHGVLVVGYGTYQGSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYPLV 330

[Close]

BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6])

HSP 1 Score: 140.969 bits (354), Expect = 3.099e-42
Identity = 65/120 (54.17%), Postives = 88/120 (73.33%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C +  S V A  T +  I  G+E  L +AVATVGPVSV +DA    +Q Y +G+Y+NP CS   L+H VL++GYG+ NG ++W+VKNSWG  WG+EGYI+MS++K+NQCGIAS A+YP+V
Sbjct:  209 CHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDASQ--WQFYSSGVYDNPYCSSTQLDHGVLVIGYGNYNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYPLV 326

[Close]

BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9])

HSP 1 Score: 129.798 bits (325), Expect = 8.966e-38
Identity = 58/120 (48.33%), Postives = 84/120 (70.00%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C Y+KS + A  T F  I  G+E+ L  A+A+VGP+S+ IDA    F  Y  G+Y++P CS   L+H VL VGYG+ +G ++W+VKNSWGP WG EGYI ++++  ++CG+AS A+YP+V
Sbjct:  212 CHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPDCSSTRLDHGVLAVGYGTDDGKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYPLV 331

[Close]

BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO41322 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4P4])

HSP 1 Score: 109.383 bits (272), Expect = 4.401e-29
Identity = 52/119 (43.70%), Postives = 73/119 (61.34%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLC--LNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAY 354
            C    +++ A  T +  I  G+ S L  A+A  GP+SV IDA H     Y  G+Y  PKC      L+H+VL VGYG+++G  +W++KNSW   WG+ GY+LMS+ KDN CG+A+ A Y
Sbjct:  427 CHKKDAEIGATITGYVNITEGDLSALKTAIAQKGPISVSIDASHKSLSFYSYGVYYEPKCGNKNEDLDHSVLAVGYGTMDGKPYWMIKNSWSTHWGMNGYVLMSQ-KDNNCGVATAATY 544

[Close]

BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789])

HSP 1 Score: 139.813 bits (351), Expect = 3.596e-41
Identity = 65/121 (53.72%), Postives = 85/121 (70.25%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            +C Y    V A  T +  +  G+E  L  AVAT+GP+SV IDA H  FQ Y++G+Y+ P+CS   L+H VL VGYGS NG ++W+VKNSWG  WG +GYI MSK+K NQCGIA+ A+YP+V
Sbjct:  219 ECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQCSSSELDHGVLAVGYGSENGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYPLV 339

[Close]

BLAST of Cathepsin L vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 131.724 bits (330), Expect = 3.234e-38
Identity = 60/120 (50.00%), Postives = 79/120 (65.83%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C YD    VA+   +  I  G+E  LA AVAT+GP++V IDADH  F  Y +GIY+ P C    L+HAVL+VGYGS  G ++WI+KNSWG  WG  GY+ + ++  N CGIAS A YP++
Sbjct:  199 CFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEEGQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 318

[Close]

BLAST of Cathepsin L vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 131.724 bits (330), Expect = 3.391e-38
Identity = 60/120 (50.00%), Postives = 79/120 (65.83%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C YD    VA+   +  I  G+E  LA AVAT+GP++V IDADH  F  Y +GIY+ P C    L+HAVL+VGYGS  G ++WI+KNSWG  WG  GY+ + ++  N CGIAS A YP++
Sbjct:  213 CFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEEGQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 332

[Close]

BLAST of Cathepsin L vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 131.724 bits (330), Expect = 3.447e-38
Identity = 60/120 (50.00%), Postives = 79/120 (65.83%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C YD    VA+   +  I  G+E  LA AVAT+GP++V IDADH  F  Y +GIY+ P C    L+HAVL+VGYGS  G ++WI+KNSWG  WG  GY+ + ++  N CGIAS A YP++
Sbjct:  202 CFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEEGQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 321

[Close]

BLAST of Cathepsin L vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 131.339 bits (329), Expect = 3.561e-38
Identity = 60/120 (50.00%), Postives = 79/120 (65.83%), Query Frame = 1

Query:    4 CIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            C YD    VA+   +  I  G+E  LA AVAT+GP++V IDADH  F  Y +GIY+ P C    L+HAVL+VGYGS  G ++WI+KNSWG  WG  GY+ + ++  N CGIAS A YP++
Sbjct:  199 CFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEEGQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 318

[Close]

BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000013980.1 (SMESG000013980.1)

HSP 1 Score: 252.677 bits (644), Expect = 4.151e-84
Identity = 120/121 (99.17%), Postives = 120/121 (99.17%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KCIYDKSK VANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV
Sbjct:  323 KCIYDKSKAVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 443

[Close]

BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000014171.1 (SMESG000014171.1)

HSP 1 Score: 216.083 bits (549), Expect = 4.363e-71
Identity = 101/121 (83.47%), Postives = 110/121 (90.91%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KCIYDKSKVVANFTS+T  +PGNESDLAAAVATVGP+S+ IDADHPGFQHYK GIYNNP CS   L+HAVL+VGYGSLNG+N+WIVKNSWGP WGIEGYILMSKDKDNQCGIA+ A YPVV
Sbjct:  213 KCIYDKSKVVANFTSYTFTKPGNESDLAAAVATVGPLSIGIDADHPGFQHYKNGIYNNPTCSSEYLDHAVLVVGYGSLNGNNYWIVKNSWGPHWGIEGYILMSKDKDNQCGIATQAVYPVV 333

[Close]

BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000014016.1 (SMESG000014016.1)

HSP 1 Score: 185.267 bits (469), Expect = 1.225e-59
Identity = 92/121 (76.03%), Postives = 100/121 (82.64%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KCIYDKSKVVANFTS+T  +  NESDLAAAVATVGP+SV IDA     Q+YK GIYNNP CS   L H VL+VGYGSLNGDN+WIVKNSWG D+GI GYILMSKDKDNQCGIA+ A YPVV
Sbjct:  165 KCIYDKSKVVANFTSYTFTKQRNESDLAAAVATVGPMSVGIDARDWRLQYYKNGIYNNPNCSSEYLGHYVLVVGYGSLNGDNYWIVKNSWGTDYGIGGYILMSKDKDNQCGIATRAVYPVV 285

[Close]

BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000013992.1 (SMESG000013992.1)

HSP 1 Score: 186.037 bits (471), Expect = 2.401e-59
Identity = 92/121 (76.03%), Postives = 100/121 (82.64%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KCIYDKSKVVANFTS+T  +  NESDLAAAVATVGP+SV IDA     Q+YK GIYNNP CS   L H VL+VGYGSLNGDN+WIVKNSWG D+GI GYILMSKDKDNQCGIA+ A YPVV
Sbjct:  213 KCIYDKSKVVANFTSYTFTKQRNESDLAAAVATVGPLSVGIDARDWRLQYYKNGIYNNPNCSSEYLGHYVLVVGYGSLNGDNYWIVKNSWGTDYGIGGYILMSKDKDNQCGIATRAVYPVV 333

[Close]

BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000014167.1 (SMESG000014167.1)

HSP 1 Score: 164.851 bits (416), Expect = 3.811e-51
Identity = 79/121 (65.29%), Postives = 94/121 (77.69%), Query Frame = 1

Query:    1 KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQHYKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYILMSKDKDNQCGIASLAAYPVV 363
            KC YD+SKVV   + FT I+ GNESDLA AVATVGPVSV IDA H  FQ YK GIYN P+CS   L+H VL VGYGS NG N+W+VKNSWG  WG+ GYI MSKD++NQCGI++ A++P+V
Sbjct:  213 KCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 333

The following BLAST results are available for this feature:

BLAST of Cathepsin L vs. Ensembl Human
BLAST of Cathepsin L vs. Ensembl Celegans
BLAST of Cathepsin L vs. Ensembl Fly
BLAST of Cathepsin L vs. Ensembl Zebrafish
BLAST of Cathepsin L vs. Ensembl Xenopus
BLAST of Cathepsin L vs. Ensembl Mouse
BLAST of Cathepsin L vs. UniProt/SwissProt
BLAST of Cathepsin L vs. TrEMBL
BLAST of Cathepsin L vs. Ensembl Cavefish
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
BLAST of Cathepsin L vs. Ensembl Yeast
BLAST of Cathepsin L vs. Ensembl Nematostella
BLAST of Cathepsin L vs. Ensembl Medaka
BLAST of Cathepsin L vs. Planmine SMEST

BLAST of Cathepsin L vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CTSV	2.023e-41	54.84	cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538]	[more]
CTSV	2.023e-41	54.84	cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538]	[more]
CTSL	2.419e-36	54.03	cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]	[more]
CTSL	2.419e-36	54.03	cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]	[more]
CTSS	3.431e-36	49.59	cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545]	[more]

BLAST of Cathepsin L vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cpl-1	3.340e-35	47.15	CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H...	[more]
cpl-1	3.340e-35	47.15	CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H...	[more]
cpl-1	3.022e-34	47.15	CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H...	[more]
tag-196	4.397e-19	37.93	pep chromosome:WBcel235:V:8594914:8597500:1 gene:W...	[more]
tag-196	4.397e-19	37.93	pep chromosome:WBcel235:V:8594914:8597469:1 gene:W...	[more]

BLAST of Cathepsin L vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cp1	2.632e-40	52.07	gene:FBgn0013770 transcript:FBtr0304021	[more]
Cp1	7.271e-40	52.07	gene:FBgn0013770 transcript:FBtr0087592	[more]
Cp1	1.033e-39	52.07	gene:FBgn0013770 transcript:FBtr0087593	[more]
Cp1	1.047e-39	52.07	gene:FBgn0013770 transcript:FBtr0339955	[more]
CG4847	8.733e-26	43.33	gene:FBgn0034229 transcript:FBtr0086934	[more]

BLAST of Cathepsin L vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ctsl.1	8.741e-47	58.68	cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]	[more]
ctsl.1	8.741e-47	58.68	cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]	[more]
ctsl.1	8.741e-47	58.68	cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]	[more]
cts12	1.214e-39	52.50	cathepsin 12 [Source:ZFIN;Acc:ZDB-GENE-050208-336]	[more]
cts12	1.619e-39	52.50	cathepsin 12 [Source:ZFIN;Acc:ZDB-GENE-050208-336]	[more]

BLAST of Cathepsin L vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fcrl2	6.165e-38	52.00	Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590...	[more]
fcrl2	6.802e-38	52.00	Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590...	[more]
mdk	1.778e-37	50.41	midkine [Source:Xenbase;Acc:XB-GENE-488502]	[more]
mdk	2.909e-37	50.41	midkine [Source:Xenbase;Acc:XB-GENE-488502]	[more]
harbi1	2.335e-35	50.41	harbinger transposase derived 1 [Source:Xenbase;Ac...	[more]

BLAST of Cathepsin L vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
4930486L24Rik	1.091e-39	52.00	RIKEN cDNA 4930486L24 gene [Source:MGI Symbol;Acc:...	[more]
Ctsl	7.147e-39	53.23	cathepsin L [Source:MGI Symbol;Acc:MGI:88564]	[more]
Ctsl	7.147e-39	53.23	cathepsin L [Source:MGI Symbol;Acc:MGI:88564]	[more]
Ctsll3	6.879e-38	53.72	cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917...	[more]
BC051665	7.037e-37	52.89	cDNA sequence BC051665 [Source:MGI Symbol;Acc:MGI:...	[more]

BLAST of Cathepsin L vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O60911\|CATL2_HUMAN	9.717e-41	54.84	Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 ...	[more]
sp\|P09648\|CATL1_CHICK	9.987e-40	55.00	Cathepsin L1 (Fragments) OS=Gallus gallus OX=9031 ...	[more]
sp\|Q80UB0\|TEST2_MOUSE	7.634e-39	52.00	Testin-2 OS=Mus musculus OX=10090 PE=2 SV=1	[more]
sp\|Q95029\|CATL_DROME	1.035e-38	52.07	Cathepsin L OS=Drosophila melanogaster OX=7227 GN=...	[more]
sp\|P06797\|CATL1_MOUSE	4.999e-38	53.23	Cathepsin L1 OS=Mus musculus OX=10090 GN=Ctsl PE=1...	[more]

BLAST of Cathepsin L vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0N9WMD3	1.101e-45	57.02	Cathepsin L OS=Cerebratulus lacteus OX=6221 PE=2 S...	[more]
A0A1I8IYR5	1.636e-45	58.68	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8IU52	1.818e-45	58.68	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267GB11	1.915e-45	58.68	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267DZX3	1.915e-45	58.68	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of Cathepsin L vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ctsl.1	8.248e-43	55.00	cathepsin L1-like [Source:NCBI gene;Acc:103023607]	[more]
ENSAMXT00000034444.1	1.441e-42	55.83	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000001797.2	1.813e-42	55.83	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000042132.1	8.078e-39	54.17	cathepsin L1-like [Source:NCBI gene;Acc:103023924]	[more]
ENSAMXT00000048039.1	8.078e-39	54.17	cathepsin L1-like [Source:NCBI gene;Acc:103023924]	[more]

BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000007755.1	1.067e-41	51.64	pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 g...	[more]
ENSPMAT00000006499.1	1.575e-40	53.60	pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 g...	[more]
ENSPMAT00000011285.1	5.636e-36	53.72	pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gen...	[more]
ENSPMAT00000010475.1	7.995e-35	49.59	pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ...	[more]
ENSPMAT00000003800.1	2.586e-34	50.41	pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 g...	[more]

BLAST of Cathepsin L vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Cathepsin L vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46465	2.255e-45	55.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36727	6.763e-44	52.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45953	3.099e-42	54.17	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45852	8.966e-38	48.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41322	4.401e-29	43.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Cathepsin L vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ctsl.1	3.596e-41	53.72	cathepsin L1 [Source:NCBI gene;Acc:101171789]	[more]
cts12	3.234e-38	50.00	cathepsin L1-like [Source:NCBI gene;Acc:101170830]	[more]
cts12	3.391e-38	50.00	cathepsin L1-like [Source:NCBI gene;Acc:101170830]	[more]
cts12	3.447e-38	50.00	cathepsin L1-like [Source:NCBI gene;Acc:101170830]	[more]
cts12	3.561e-38	50.00	cathepsin L1-like [Source:NCBI gene;Acc:101170830]	[more]

BLAST of Cathepsin L vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000013980.1	4.151e-84	99.17	SMESG000013980.1	[more]
SMESG000014171.1	4.363e-71	83.47	SMESG000014171.1	[more]
SMESG000014016.1	1.225e-59	76.03	SMESG000014016.1	[more]
SMESG000013992.1	2.401e-59	76.03	SMESG000013992.1	[more]
SMESG000014167.1	3.811e-51	65.29	SMESG000014167.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016824 ID=SMED30016824|Name=Cathepsin L|organism=Schmidtea mediterranea sexual|type=transcript|length=375bp
AAATGTATTTATGATAAATCAAAAGTTGTTGCAAATTTCACTTCGTTTAC
TGTTATCGAGCCAGGAAACGAATCTGACTTGGCAGCCGCCGTGGCCACCG
TTGGACCTGTGTCCGTATGCATCGATGCCGATCATCCAGGTTTCCAACAT
TATAAAACTGGTATTTACAATAACCCCAAATGTTCATTTTTATGCTTAAA
TCATGCCGTTTTAATCGTTGGTTATGGATCACTCAATGGAGATAACTTTT
GGATTGTGAAGAACAGTTGGGGACCAGATTGGGGAATAGAAGGATACATA
CTCATGTCAAAGGACAAGGACAACCAATGTGGAATTGCTAGTCTAGCCGC
TTATCCAGTGGTCTAATATGCATGC

protein sequence of SMED30016824-orf-1

>SMED30016824-orf-1 ID=SMED30016824-orf-1|Name=SMED30016824-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=122bp
KCIYDKSKVVANFTSFTVIEPGNESDLAAAVATVGPVSVCIDADHPGFQH
YKTGIYNNPKCSFLCLNHAVLIVGYGSLNGDNFWIVKNSWGPDWGIEGYI
LMSKDKDNQCGIASLAAYPVV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR039417	Peptidase_C1A_papain-like
IPR038765	Papain-like_cys_pep_sf
IPR000668	Peptidase_C1A_C
IPR025661	Pept_asp_AS
IPR025660	Pept_his_AS

Vocabulary: **biological process**
Term	Definition
GO:0006508	proteolysis

Vocabulary: **molecular function**
Term	Definition
GO:0008234	cysteine-type peptidase activity
GO:0008233	peptidase activity
GO:0016787	hydrolase activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000668	Peptidase C1A, papain C-terminal	SMART	SM00645	pept_c1	coord: 1..120 e-value: 1.8E-8 score: 24.4
IPR000668	Peptidase C1A, papain C-terminal	PFAM	PF00112	Peptidase_C1	coord: 1..119 e-value: 3.9E-37 score: 128.4
None	No IPR available	GENE3D	G3DSA:3.90.70.10		coord: 1..121 e-value: 3.1E-42 score: 147.3
None	No IPR available	PANTHER	PTHR12411	CYSTEINE PROTEASE FAMILY C1-RELATED	coord: 2..120
None	No IPR available	PANTHER	PTHR12411:SF57	CATHEPSIN L2	coord: 2..120
IPR025660	Cysteine peptidase, histidine active site	PROSITE	PS00639	THIOL_PROTEASE_HIS	coord: 66..76
IPR025661	Cysteine peptidase, asparagine active site	PROSITE	PS00640	THIOL_PROTEASE_ASN	coord: 83..102
IPR039417	Papain-like cysteine endopeptidase	CDD	cd02248	Peptidase_C1A	coord: 1..119 e-value: 5.16427E-54 score: 166.26
IPR038765	Papain-like cysteine peptidase superfamily	SUPERFAMILY	SSF54001	Cysteine proteinases	coord: 1..121

Main menu

Cathepsin L

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 35

Owlery

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