ER lumen protein-retaining receptor

Overview


Name	ER lumen protein-retaining receptor
Smed ID	SMED30016810
Length (bp)	816

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of ER lumen protein-retaining receptor (SMED30016810) t-SNE clustered cells

Violin plots show distribution of expression levels for ER lumen protein-retaining receptor (SMED30016810) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ER lumen protein-retaining receptor (SMED30016810) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ER lumen protein-retaining receptor (SMED30016810) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016810

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30016810	h1SMcG0012470	Contig39874	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016810	h1SMcG0012470	Contig39874	newmark_ests	PMID:29674431 Fincher et al., 2018
pharynx	SMED30016810	h1SMcG0012470	dd_Smed_v4_3954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30016810	h1SMcG0012470	dd_Smed_v4_3954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016810	h1SMcG0012470	dd_Smed_v4_3954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30016810	h1SMcG0012470	dd_Smed_v4_3954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30016810	h1SMcG0012470	dd_Smed_v4_3954_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305])

HSP 1 Score: 313.923 bits (803), Expect = 2.071e-108
Identity = 146/212 (68.87%), Postives = 182/212 (85.85%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AI++LL KIWK+RSCAG+SGKSQ++FA+VF TRYLDLF  +ISLYN  MK  ++  S  TVY IY KFKATYD NHD+FR+EF++VP+GGL+ L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y++NW +RF+ E F+DLIA+ +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 293.123 bits (749), Expect = 2.946e-100
Identity = 136/211 (64.45%), Postives = 176/211 (83.41%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLP 713
            MN FR LGD+SHL+A+ILLL KIW+S+ C G+SGKSQI+FA+VF TRYLDLF  +IS+YN +MK  F++ + +TVY IY KF+ T+D  +D+FRLEF++VP+ GL+ L N+ F+ +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y+ NW  R+  E+FYD IA+ SG++QTI YCDFFYLY+TKVLKGK  +LP
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLP 211

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 291.197 bits (744), Expect = 1.635e-99
Identity = 150/212 (70.75%), Postives = 179/212 (84.43%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRFLGD+SHL+AIILLL KIWKSRSCAG+SGKSQ++FAVVF  RYLDLF  YISLYN  MK  +I  S  TV+ IY KFKATYD NHD+FR+EF++VP   LA L+NH F+ +EILWT+SIYLES+AILPQL+++SKTGEAETITSHYLFALGVYR  Y+ NW +R+  E F+DLIAI +G++QT+LYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 277.715 bits (709), Expect = 4.698e-94
Identity = 129/201 (64.18%), Postives = 168/201 (83.58%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTK 683
            MN FR LGD+SHL+A+ILLL KIW+S+ C G+SGKSQI+FA+VF TRYLDLF  +IS+YN +MK  F++ + +TVY IY KF+ T+D  +D+FRLEF++VP+ GL+ L N+ F+ +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y+ NW  R+  E+FYD IA+ SG++QTI YCDFFYLY+TK
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTK 201

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 216.468 bits (550), Expect = 6.054e-71
Identity = 101/150 (67.33%), Postives = 125/150 (83.33%), Query Frame = 3

Query:  267 MKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MK  +I  S  TV+ IY KFKATYD NHD+FR+EF++VP   LA L+NH F+ +EILWT+SIYLES+AILPQL+++SKTGEAETITSHYLFALGVYR  Y+ NW +R+  E F+DLIAI +G++QT+LYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 150

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Match: erd-2.1 (ER lumen protein-retaining receptor [Source:UniProtKB/Swiss-Prot;Acc:P48583])

HSP 1 Score: 276.559 bits (706), Expect = 4.125e-94
Identity = 126/213 (59.15%), Postives = 175/213 (82.16%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLK-GKAFTLPA 716
            MN FRF  D++H IAI++LL KIWKSRSC G+SG+SQ++FA+VF TRYLDLF  + S YN  MK F++++S  TVY ++ KFKATYD N+DSFR+EF+++P   LA+LINH+F F+E++WT+SIYLE++AI+PQL+++S+TG AETIT+HYLFALG YR  YILNW YR++ E F+D I++ +GI+QT+LY DFFYLY+T+V++  + F + A
Sbjct:    1 MNLFRFTADVAHAIAIVVLLLKIWKSRSCEGISGRSQLLFALVFVTRYLDLFTNFFSFYNTAMKIFYLVASFGTVYLMWAKFKATYDRNNDSFRIEFLVIPSMILALLINHEFIFMEVMWTFSIYLEAVAIMPQLFMLSRTGNAETITAHYLFALGSYRFLYILNWVYRYYTESFFDPISVVAGIVQTVLYADFFYLYITRVIQSNRQFEMSA 213

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Match: erd-2.2 (Putative ER lumen protein-retaining receptor C28H8.4 [Source:UniProtKB/Swiss-Prot;Acc:Q09473])

HSP 1 Score: 251.906 bits (642), Expect = 2.375e-84
Identity = 126/212 (59.43%), Postives = 165/212 (77.83%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKG-KAFTLP 713
            MN FR   DMSHL+AII+LL KIWKSRSC+G+S +SQI+FA+VF  RYLDLF  YISLYN  MK  F+ ++  TVY ++FKF++TY    D+FR+E ++VP   LA+LINH F+  E+LWT+SIYLE++AILPQL+L+  TG AE IT+HYLFALG YRA YI NW YR++ ED++D I + +GI+QT+LY DFFYLY+T+V++  K   LP
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELP 212

[Close]

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKG-KAFTLP 713
            MN FR   DMSHL+AII+LL KIWKSRSC+G+S +SQI+FA+VF  RYLDLF  YISLYN  MK  F+ ++  TVY ++FKF++TY    D+FR+E ++VP   LA+LINH F+  E+LWT+SIYLE++AILPQL+L+  TG AE IT+HYLFALG YRA YI NW YR++ ED++D I + +GI+QT+LY DFFYLY+T+V++  K   LP
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELP 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080021)

HSP 1 Score: 322.398 bits (825), Expect = 3.518e-112
Identity = 148/212 (69.81%), Postives = 183/212 (86.32%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRF GD+SH+ AII+LL KIWK+RSCAG+SGKSQI+FAVV+ TRYLDLF  Y+SLYN +MK  F+ +S  TVY +Y KFKATYD NHDSFR+EF++VP   L+++INH+F+ +E+LWT+SIYLES+AILPQL+L+S+TGEAE+ITSHYLFALG YRA Y+LNW YR+ VE  YDLIAIF+G++QT+LYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080023)

HSP 1 Score: 322.398 bits (825), Expect = 3.518e-112
Identity = 148/212 (69.81%), Postives = 183/212 (86.32%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRF GD+SH+ AII+LL KIWK+RSCAG+SGKSQI+FAVV+ TRYLDLF  Y+SLYN +MK  F+ +S  TVY +Y KFKATYD NHDSFR+EF++VP   L+++INH+F+ +E+LWT+SIYLES+AILPQL+L+S+TGEAE+ITSHYLFALG YRA Y+LNW YR+ VE  YDLIAIF+G++QT+LYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080022)

HSP 1 Score: 322.398 bits (825), Expect = 3.518e-112
Identity = 148/212 (69.81%), Postives = 183/212 (86.32%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRF GD+SH+ AII+LL KIWK+RSCAG+SGKSQI+FAVV+ TRYLDLF  Y+SLYN +MK  F+ +S  TVY +Y KFKATYD NHDSFR+EF++VP   L+++INH+F+ +E+LWT+SIYLES+AILPQL+L+S+TGEAE+ITSHYLFALG YRA Y+LNW YR+ VE  YDLIAIF+G++QT+LYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr2a (KDEL endoplasmic reticulum protein retention receptor 2a [Source:NCBI gene;Acc:373129])

HSP 1 Score: 315.079 bits (806), Expect = 4.412e-109
Identity = 149/212 (70.28%), Postives = 179/212 (84.43%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWKSRSCAG+SGKSQI+FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KF+ATYD NHD+FR EF++VP+GGLA L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LGVYRA Y+ NW +RF+ E F+D+IAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr2b (KDEL endoplasmic reticulum protein retention receptor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-4189])

HSP 1 Score: 312.383 bits (799), Expect = 4.537e-108
Identity = 148/212 (69.81%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWKSRSCAG+SGKSQI+FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KFKATYD NHD+FR+EF++VP+GGLA L+NH FS +EILWT+SIYLES++ILPQL++ISKTGEAETIT+HYLF LG+YRA Y+ NW +RF+ E F+D+IAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNLFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTSMKVIYIACAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVSILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:393613])

HSP 1 Score: 271.937 bits (694), Expect = 4.237e-92
Identity = 128/212 (60.38%), Postives = 169/212 (79.72%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKA-FTLP 713
            MN FR  GD+ HLIAII+L  KIW+S+SCAG+SGKSQ++FA+VF TRYLDLF  YIS YN +MK  +++ +  TV  I+F+F+ +YD   DSFR+EF++VP+ GL+ L N+ F+ +EILWT+SIYLES+AILPQL++I+KTGEAE+IT+HYL  LG+YRA Y+ NW +RF  E FYD IA+ SG++QTI YCDFFYLY T+VL+G    +LP
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212

[Close]

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKA-FTLP 713
            MN FR  GD+ HLIAII+L  KIW+S+SCAG+SGKSQ++FA+VF TRYLDLF  YIS YN +MK  +++ +  TV  I+F+F+ +YD   DSFR+EF++VP+ GL+ L N+ F+ +EILWT+SIYLES+AILPQL++I+KTGEAE+IT+HYL  LG+YRA Y+ NW +RF  E FYD IA+ SG++QTI YCDFFYLY T+VL+G    +LP
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Match: CABZ01075611.1 (pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDARG00000104519.2 transcript:ENSDART00000165169.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01075611.1)

HSP 1 Score: 174.866 bits (442), Expect = 3.679e-54
Identity = 79/128 (61.72%), Postives = 105/128 (82.03%), Query Frame = 3

Query:  300 TVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTK 683
            TV  I+F+F+ +YD   DSFR+EF++VP+ GL+ L N+ F+ +EILWT+SIYLES+AILPQL++I+KTGEAE+IT+HYL  LG+YRA Y+ NW +RF  E FYD IA+ SG++QTI YCDFFYLY T+
Sbjct:   48 TVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTR 175

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: kdelr1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:NCBI gene;Acc:395012])

HSP 1 Score: 311.997 bits (798), Expect = 9.586e-108
Identity = 148/212 (69.81%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWKSRSCAG+SGKSQ++FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KFKATYD NHD+FR+EF++VP+GGL+VL+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y+ NW +R+  E F+DLIAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNVFRLSGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTSMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSVLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRYSFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: kdelr2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:496456])

HSP 1 Score: 309.686 bits (792), Expect = 7.021e-107
Identity = 146/212 (68.87%), Postives = 181/212 (85.38%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRFLGD+SHL AI++LL KIWKSRSCAG+SGKSQ++FA+VF TRYLDLF  +ISLYN  MK  ++ SS  T++ IY KFKATYD NHD+FR+EF++VP   LA L+NH F+ +EILWT+SIYLES+AILPQL+++SKTGEAETITSHYLFALG+YRA Y+ NW +R+  E F+DLIAI +G++QT+LYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRFLGDISHLSAILILLLKIWKSRSCAGISGKSQLLFAIVFTTRYLDLFTNFISLYNTSMKMVYVASSYATIWMIYSKFKATYDGNHDTFRVEFLIVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGIYRALYLFNWIWRYQFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Match: stx1a (syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753])

HSP 1 Score: 266.159 bits (679), Expect = 2.855e-89
Identity = 133/216 (61.57%), Postives = 176/216 (81.48%), Query Frame = 3

Query:   75 FKMNAFRFL---GDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLP 713
            F +  +R L   GD+SHL+AII+LL K+WKS+SCAG+SGKSQ++FA+VF TRYLDLF V+IS YN +MK  F++ + +TVY IY KF+  YD  +D+FRLEF++VP+ GL+ L N++F+ +EILWT+SIYLES+AILPQL++ISKTGEAE+IT+HYLF LG+YR  Y+ NW +R+  E FYD IA+ SG++QTI Y DFFYLY+TKVLKGK  +LP
Sbjct:   25 FPVTTYRHLWISGDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISAYNTVMKIVFLVCAYVTVYLIYGKFRKAYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILWTFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIAVVSGVVQTIFYFDFFYLYITKVLKGKKLSLP 240

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr2 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 [Source:MGI Symbol;Acc:MGI:1914163])

HSP 1 Score: 313.923 bits (803), Expect = 1.407e-108
Identity = 147/212 (69.34%), Postives = 182/212 (85.85%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AI++LL KIWK+RSCAG+SGKSQ++FA+VF TRYLDLF  +ISLYN  MK  +I  S  TVY IY KFKATYD NHD+FR+EF++VP+GGL+ L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y++NW +RF+ E F+DLIA+ +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr3 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 [Source:MGI Symbol;Acc:MGI:2145953])

HSP 1 Score: 295.049 bits (754), Expect = 3.674e-101
Identity = 134/212 (63.21%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR LGD+SHL+A+ILLL KIW+S+SCAG+SGKSQI+FA+VF TRYLDLF  +IS+YN +MK  F++ + +TVY IY+KF+ T+D+ +D+FRLEF++VP+ GL+ L+N+ ++ +E+LWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YR  Y+ NW  R+  E+FYD I++ SG++QTI YCDFFYLY+TKVLKGK  +LP 
Sbjct:    1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYNTVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPVTGLSFLVNYSYTPMEVLWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQISVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPV 212

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 291.197 bits (744), Expect = 1.028e-99
Identity = 150/212 (70.75%), Postives = 179/212 (84.43%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRFLGD+SHL+AIILLL KIWKSRSCAG+SGKSQ++FAVVF  RYLDLF  YISLYN  MK  +I  S  TV+ IY KFKATYD NHD+FR+EF++VP   LA L+NH F+ +EILWT+SIYLES+AILPQL+++SKTGEAETITSHYLFALGVYR  Y+ NW +R+  E F+DLIAI +G++QT+LYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 216.468 bits (550), Expect = 4.535e-71
Identity = 101/150 (67.33%), Postives = 125/150 (83.33%), Query Frame = 3

Query:  267 MKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MK  +I  S  TV+ IY KFKATYD NHD+FR+EF++VP   LA L+NH F+ +EILWT+SIYLES+AILPQL+++SKTGEAETITSHYLFALGVYR  Y+ NW +R+  E F+DLIAI +G++QT+LYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 150

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 175.637 bits (444), Expect = 3.446e-55
Identity = 96/137 (70.07%), Postives = 114/137 (83.21%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYL 491
            MN FRFLGD+SHL+AIILLL KIWKSRSCAG+SGKSQ++FAVVF  RYLDLF  YISLYN  MK  +I  S  TV+ IY KFKATYD NHD+FR+EF++VP   LA L+NH F+ +EILWT+SIYLES+AILPQL++
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFM 137

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BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|O76767|ERD2_DROME (ER lumen protein-retaining receptor OS=Drosophila melanogaster OX=7227 GN=KdelR PE=2 SV=1)

HSP 1 Score: 322.398 bits (825), Expect = 3.527e-111
Identity = 148/212 (69.81%), Postives = 183/212 (86.32%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRF GD+SH+ AII+LL KIWK+RSCAG+SGKSQI+FAVV+ TRYLDLF  Y+SLYN +MK  F+ +S  TVY +Y KFKATYD NHDSFR+EF++VP   L+++INH+F+ +E+LWT+SIYLES+AILPQL+L+S+TGEAE+ITSHYLFALG YRA Y+LNW YR+ VE  YDLIAIF+G++QT+LYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q6PEH1|ERD22_DANRE (ER lumen protein-retaining receptor 2 OS=Danio rerio OX=7955 GN=kdelr2 PE=2 SV=1)

HSP 1 Score: 315.079 bits (806), Expect = 3.330e-108
Identity = 149/212 (70.28%), Postives = 179/212 (84.43%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWKSRSCAG+SGKSQI+FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KF+ATYD NHD+FR EF++VP+GGLA L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LGVYRA Y+ NW +RF+ E F+D+IAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q5ZKX9|ERD22_CHICK (ER lumen protein-retaining receptor 2 OS=Gallus gallus OX=9031 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 313.923 bits (803), Expect = 9.732e-108
Identity = 147/212 (69.34%), Postives = 182/212 (85.85%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWKSRSCAG+SGKSQ++FA+VF TRYLDLF  +ISLYN  MK  +I  S  TVY IY KFKATYD NHD+FR+EF++VP+GGL+ L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y++NW +R++ E F+DLIA+ +G++QT+LYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLIVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRYYFEGFFDLIAVVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q5U305|ERD22_RAT (ER lumen protein-retaining receptor 2 OS=Rattus norvegicus OX=10116 GN=Kdelr2 PE=2 SV=1)

HSP 1 Score: 313.923 bits (803), Expect = 9.839e-108
Identity = 147/212 (69.34%), Postives = 182/212 (85.85%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AI++LL KIWK+RSCAG+SGKSQ++FA+VF TRYLDLF  +ISLYN  MK  +I  S  TVY IY KFKATYD NHD+FR+EF++VP+GGL+ L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y++NW +RF+ E F+DLIA+ +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Match: sp|Q9CQM2|ERD22_MOUSE (ER lumen protein-retaining receptor 2 OS=Mus musculus OX=10090 GN=Kdelr2 PE=1 SV=1)

HSP 1 Score: 313.923 bits (803), Expect = 9.839e-108
Identity = 147/212 (69.34%), Postives = 182/212 (85.85%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AI++LL KIWK+RSCAG+SGKSQ++FA+VF TRYLDLF  +ISLYN  MK  +I  S  TVY IY KFKATYD NHD+FR+EF++VP+GGL+ L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y++NW +RF+ E F+DLIA+ +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: B3MJH8 (ER lumen protein-retaining receptor OS=Drosophila ananassae OX=7217 GN=Dana\GF15788 PE=3 SV=1)

HSP 1 Score: 325.865 bits (834), Expect = 5.812e-110
Identity = 152/212 (71.70%), Postives = 184/212 (86.79%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRF GD+SH+ AII+LL KIWK+RSCAG+SGKSQI+FAVV+ TRYLDLF  Y+SLYN +MK  F+ +S  TVYF+Y KFKATYD NHDSFR+EF++VP   L+++INH+F+ +E+LWT+SIYLES+AILPQL+L+SKTGEAE+ITSHYLFALG YRA Y+LNW YR+ VE  YDLIAIF+GI+QTILYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYFMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSKTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGIVQTILYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A1B6FB24 (ER lumen protein-retaining receptor OS=Cuerna arida OX=1464854 GN=g.35741 PE=3 SV=1)

HSP 1 Score: 325.094 bits (832), Expect = 1.097e-109
Identity = 149/212 (70.28%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR LGD+SHL+AII+LL KIWKSRSCAG+SGKSQ++FA+V+  RYLDL   YIS YN  MK FF+ +S  T+Y +Y KFKATYD NHD+FR+EF+++P  GLA+LINH F  +EILWT+SIYLES+AILPQL+L+SKTGEAE+ITSHYLFALG YRA Y+LNW YR++ ED YDLIAI +GI+QT+LYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRLLGDLSHLLAIIILLQKIWKSRSCAGISGKSQVLFAIVYTARYLDLVTTYISAYNTTMKVFFLAASYGTIYLMYIKFKATYDHNHDTFRIEFLVIPAAGLALLINHAFDVLEILWTFSIYLESVAILPQLFLVSKTGEAESITSHYLFALGSYRALYLLNWIYRYYAEDHYDLIAIVAGIVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: A0A1B6JPH9 (ER lumen protein-retaining receptor OS=Homalodisca liturata OX=320908 GN=g.47106 PE=3 SV=1)

HSP 1 Score: 325.094 bits (832), Expect = 1.097e-109
Identity = 149/212 (70.28%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR LGD+SHL+AII+LL KIWKSRSCAG+SGKSQ++FA+V+  RYLDL   YIS YN  MK FF+ +S  T+Y +Y KFKATYD NHD+FR+EF+++P  GLA+LINH F  +EILWT+SIYLES+AILPQL+L+SKTGEAE+ITSHYLFALG YRA Y+LNW YR++ ED YDLIAI +GI+QT+LYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRLLGDLSHLLAIIILLQKIWKSRSCAGISGKSQVLFAIVYTARYLDLVTTYISAYNTTMKVFFLAASYGTIYLMYIKFKATYDHNHDTFRIEFLVIPAAGLALLINHAFDVLEILWTFSIYLESVAILPQLFLVSKTGEAESITSHYLFALGSYRALYLLNWIYRYYAEDHYDLIAIVAGIVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: H2UVE4 (ER lumen protein-retaining receptor OS=Takifugu rubripes OX=31033 GN=LOC101066257 PE=3 SV=1)

HSP 1 Score: 324.709 bits (831), Expect = 1.523e-109
Identity = 154/212 (72.64%), Postives = 182/212 (85.85%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWKSRSCAG+SGKSQI+FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KF+ATYD NHDSFR+EF++VP+GGLAVLINH FSF+EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA YI NW +RF+ E F+DLIAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFAIVFTTRYLDLLSTFISLYNSCMKVIYIGCAYATVYMIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSFMEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYIFNWVWRFYFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Match: B4NZP5 (ER lumen protein-retaining receptor OS=Drosophila yakuba OX=7245 GN=Dyak\GE18943 PE=3 SV=1)

HSP 1 Score: 323.939 bits (829), Expect = 2.750e-109
Identity = 149/212 (70.28%), Postives = 183/212 (86.32%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FRF GD+SH+ AII+LL KIWK+RSCAG+SGKSQI+FAVV+ TRYLDLF  Y+SLYN +MK  F+ +S  TVY +Y KFKATYD NHDSFR+EF++VP   LA++INH+F+ +E+LWT+SIYLES+AILPQL+L+S+TGEAE+ITSHYLFALG YRA Y+LNW YR+ VE  YDLIAIF+G++QT+LYCDFFYLY+TKVLKGK   LPA
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLALVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: kdelr2a (ER lumen protein-retaining receptor 2-like [Source:NCBI gene;Acc:103040303])

HSP 1 Score: 317.005 bits (811), Expect = 5.948e-110
Identity = 149/212 (70.28%), Postives = 181/212 (85.38%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWK+RSCAG+SGKSQI+FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KFKATYD NHD+FR+EF++VP+GGLA L+NH FS +EI+WT+SIYLES+AILPQL+LISKTGEAETIT+HYLF+LGVYRA Y+ NW +RF+ E F+D+IAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLAGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRIEFLIVPVGGLAFLVNHDFSPLEIMWTFSIYLESVAILPQLFLISKTGEAETITTHYLFSLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:103025946])

HSP 1 Score: 314.309 bits (804), Expect = 5.985e-109
Identity = 149/212 (70.28%), Postives = 181/212 (85.38%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWKSRSCAG+SGKSQI+FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KFKATYD NHD+FR+EF++VP+GGLA L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y++NW +RF+ E F+D+IAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLINWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: KDELR3 (ER lumen protein-retaining receptor 3 [Source:NCBI gene;Acc:103035602])

HSP 1 Score: 281.952 bits (720), Expect = 4.514e-96
Identity = 130/212 (61.32%), Postives = 173/212 (81.60%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKA-FTLP 713
            MN FR  GD+SHL+AIILL  KIW+S+SCAG+SGKSQ++FAVVF TRYLDLF  +IS+YN +MK  F++ +  TVY IY +F+ +YD  +DSFR+EF++VP+ GL+ L N+ F+ +EILWT+SIYLES+AILPQL++I+KTGEAE+IT+HYLF LG+YRA Y+ NW +R+  E F+D IA+ SG++QTI YCDFFYLY T+VL+G    +LP
Sbjct:    1 MNVFRLCGDVSHLVAIILLFLKIWRSKSCAGISGKSQVLFAVVFTTRYLDLFTGFISIYNTVMKVVFLVLAYATVYLIYLRFRNSYDSENDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITTHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: ENSAMXT00000042346.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000042346.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 122.479 bits (306), Expect = 9.635e-34
Identity = 88/231 (38.10%), Postives = 120/231 (51.95%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLV---YISLYNVLMKAFFIISSLLTVYFIY--FKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVE-------------ILWTYSIYLESLAILPQLYLISKTGEAETI-TSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKA-FTLP 713
            MN FR  GD+S    + + L         AG+SGKSQ+  AV  +     +      +IS+YN +MK   +    + + FIY    F+ +YD       + FI    GG    +    SF+E             ILWT+SIYLES+           TGEAE+    HYLF LG+YRA Y+ NW +R+  E F+D IA+ SG++QTI YCDFFYLY T+VL+G    +LP
Sbjct:    1 MNVFRLCGDVSAFSCLCVCLCVC------AGISGKSQV--AVCLWCSPHGILTCSTGFISIYNTVMKVGCLPGVGIPLQFIYSTCAFRNSYDSG-----MHFIS---GGSCCSVA-GLSFLEKLTPSTPTGGNTPILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 203

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Match: ENSAMXT00000040094.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000040094.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 112.464 bits (280), Expect = 2.894e-30
Identity = 76/216 (35.19%), Postives = 103/216 (47.69%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLV---YISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETI-TSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKA-FTLP 713
            MN FR  GD+S     + L         CAG+SGKSQ+  AV  +     +      +IS+YN +MK      +                 +  +                        +ILWT+SIYLES+           TGEAE+    HYLF LG+YRA Y+ NW +R+  E F+D IA+ SG++QTI YCDFFYLY T+VL+G    +LP
Sbjct:    1 MNVFRLCGDVSAFSLCVCLC-------VCAGISGKSQV--AVCLWCSPHGILTCSTGFISIYNTVMKVGKHKHTHKHHTQHTHTHTPHTHTHTTTHPHS--------------------QILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLP 176

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BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 295.434 bits (755), Expect = 3.979e-102
Identity = 147/212 (69.34%), Postives = 185/212 (87.26%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL+AII+LL KIWK+RSCAG+SGKSQI+FA+VF TRYLDLF  +IS+YN  MK  ++  +  T++ IY KFKATYD N+D+FR+EF++VP+GGL+VL+NH FS +EILWT+SIYLES+AILPQL+L+SKTGEAETITSHYLFALG+YRA Y+LNW +R++ E F+DLIAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNVFRLTGDLSHLLAIIILLIKIWKTRSCAGISGKSQILFALVFTTRYLDLFTTFISIYNTSMKVVYMACAYATLWMIYHKFKATYDGNNDTFRVEFLVVPIGGLSVLVNHDFSLLEILWTFSIYLESVAILPQLFLVSKTGEAETITSHYLFALGLYRALYLLNWIWRYYFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 289.656 bits (740), Expect = 6.495e-100
Identity = 146/212 (68.87%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL+AII+LL KIWK+RSCAG+SGKSQI+FA+VF TRYLDL   YISLYN  MK  +I  S  TV+ IY KFKATYD NHD+FR+EF+++P+  L++++NH +S VEILWT+SIYLES+AILPQL+++SKTGEAETITSHYLFALGVYR  Y+ NW +R+F E F+DLIAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNVFRLAGDLSHLLAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTNYISLYNTTMKVIYIGCSYATVWMIYSKFKATYDSNHDTFRVEFLVLPVALLSLVVNHDYSVVEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYFAEGFFDLIAIVAGLVQTILYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
Match: ERD2 (HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins [Source:SGD;Acc:S000000136])

HSP 1 Score: 206.838 bits (525), Expect = 2.350e-67
Identity = 103/218 (47.25%), Postives = 157/218 (72.02%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLV-YISLYNVLMKAFFIISSLLTVYFIYFKFKAT---YD--LNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFY-DLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLP 713
            MN FR LGD+SHL +I++L++ I  +R   G+S K+Q ++A+VF TRYLDL    ++SLYN LMK FFI+S+   V  +    +     Y+  L HD+F+++ +++    ++V  +HKF+F+E+ W++S++LES+AILPQLY++SK G+  ++T HY+FA+G+YRA YI NW +R+  ED   D IA F+G++QT+LY DFFY+Y TKV++GK F LP
Sbjct:    1 MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLP 218

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
Match: EDO48388 (ER lumen protein retaining receptor [Source:UniProtKB/TrEMBL;Acc:A7RJJ4])

HSP 1 Score: 317.775 bits (813), Expect = 9.986e-111
Identity = 145/212 (68.40%), Postives = 181/212 (85.38%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR +GD+SHL+AIILLL KIWK+RSCAG+SGKSQ+MFA+VF TRYLDLF  ++SLYN +MK  +I  +  T+Y +Y KFKATYD NHD+FR+EF+++P+ GLA L+NH+F+ +E+LWT+SIYLES+AILPQL++ISKTGEAE+ITSHYLFALG YRA YI NW YR++ E FYD IAI +G +QT LYCDFFYLY+TKVLKGK+  LPA
Sbjct:    1 MNIFRLVGDLSHLVAIILLLWKIWKTRSCAGVSGKSQMMFALVFSTRYLDLFTSFVSLYNSVMKVIYISCAFATLYLMYIKFKATYDSNHDTFRVEFLLIPVAGLACLVNHEFTIMEVLWTFSIYLESVAILPQLFMISKTGEAESITSHYLFALGAYRALYIANWVYRYYFEGFYDFIAIVAGCVQTALYCDFFYLYITKVLKGKSLKLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: KDELR2 (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101157057])

HSP 1 Score: 318.546 bits (815), Expect = 1.297e-109
Identity = 150/212 (70.75%), Postives = 181/212 (85.38%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWK+RSCAG+SGKSQI+FA+VF TRYLDL   +ISLYN  MK  +I  S  TVY IY KF+ATYD NHDSFR+EF++VP+GGLAVLINH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y+ NW +RF+ E F+D+IAI +G++QT+LYCDFFYLY+TKVLKGK  +LPA
Sbjct:   60 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNSSMKVIYIGCSYATVYLIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 271

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: kdelr2b (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101160362])

HSP 1 Score: 311.612 bits (797), Expect = 6.899e-108
Identity = 147/212 (69.34%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GD+SHL AII+LL KIWK+RSCAG+SGKSQ++FA+VF TRYLDL   +ISLYN  MK  +I  +  TVY IY KFKATYD NHD+FR+EF++VP+GGLA L+NH FS +EILWT+SIYLES+AILPQL++ISKTGEAETIT+HYLF LG+YRA Y+ NW +RF+ E F+D+IAI +G++QTILYCDFFYLY+TKVLKGK  +LPA
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYVKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:101155114])

HSP 1 Score: 280.411 bits (716), Expect = 1.962e-95
Identity = 132/212 (62.26%), Postives = 174/212 (82.08%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKA-FTLP 713
            MN FR  GD+SHL+AII+LL KIW+SRSCAG+SGKSQ++FA+VF TRYLDLF ++IS YN +MK  F+  S  TVY IY +FK T++  +DSFRLEF++VP+ GL+ L N+ F+ +EILWT+SI+LES+AI+PQL++I+KTGEAE+IT+HYLF LG+YRA YI NW +R+  E F+D IA+ SG++QTI Y DFFYLY+TKVL+G+   TLP
Sbjct:    1 MNVFRLAGDVSHLVAIIILLLKIWRSRSCAGISGKSQVLFAIVFTTRYLDLFTIFISPYNTIMKVVFLALSYATVYLIYVRFKNTFNSENDSFRLEFLLVPVIGLSFLENYAFTPLEILWTFSIFLESVAIMPQLFMITKTGEAESITTHYLFFLGLYRALYIANWVWRYHTEGFFDQIAVVSGVVQTIFYIDFFYLYVTKVLRGRGKMTLP 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000073757.1 (SMESG000073757.1)

HSP 1 Score: 405.216 bits (1040), Expect = 4.764e-145
Identity = 203/203 (100.00%), Postives = 203/203 (100.00%), Query Frame = 3

Query:  108 MSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA
Sbjct:    1 MSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 203

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 310.071 bits (793), Expect = 2.631e-107
Identity = 143/212 (67.45%), Postives = 180/212 (84.91%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MN FR  GDMSHL+AII+LL KIWK+RSC+G+SGKSQIMFA+VF  RYLDLF  ++S+YN +MK  F++ + +TVY ++FKFKAT D NHD+FR EF++ P   LA+++NH FSF+EI WT+SIY+E++AILPQL+LISKTGEAE+ITSHYLFALG YRA YILNW YR++ E+F+DLIA+ SG +QTILYCDFFYLY+TKVLKG+   LPA
Sbjct:    1 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 212

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000053522.1 (SMESG000053522.1)

HSP 1 Score: 273.863 bits (699), Expect = 5.160e-93
Identity = 132/211 (62.56%), Postives = 164/211 (77.73%), Query Frame = 3

Query:   81 MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLP 713
            MN FR +GD+SHL AII+LL KIWK+RSCAG+SGK+QI+F +VF TRYLDLF  ++S YN  MK  F+     TV+FIY KF+ATY    D+FR+EFI++P   LAVL NHK   +EILWT+SIYLESLAILPQL++I+ TG AETIT HYLFALG+YRA YI+NW YR++ E  YD+I I +G +QT+ + DFFYLY T+VLKGK   LP
Sbjct:    1 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 211

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 246.128 bits (627), Expect = 1.045e-82
Identity = 114/174 (65.52%), Postives = 146/174 (83.91%), Query Frame = 3

Query:  195 MFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            MFA+VF  RYLDLF  ++S+YN +MK  F++ + +TVY ++FKFKAT D NHD+FR EF++ P   LA+++NH FSF+EI WT+SIY+E++AILPQL+LISKTGEAE+ITSHYLFALG YRA YILNW YR++ E+F+DLIA+ SG +QTILYCDFFYLY+TKVLKG+   LPA
Sbjct:    1 MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 174

[Close]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 206.838 bits (525), Expect = 8.431e-68
Identity = 94/135 (69.63%), Postives = 117/135 (86.67%), Query Frame = 3

Query:  312 IYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLPA 716
            ++FKFKAT D NHD+FR EF++ P   LA+++NH FSF+EI WT+SIY+E++AILPQL+LISKTGEAE+ITSHYLFALG YRA YILNW YR++ E+F+DLIA+ SG +QTILYCDFFYLY+TKVLKG+   LPA
Sbjct:    1 MWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 135

The following BLAST results are available for this feature:

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
BLAST of ER lumen protein-retaining receptor vs. TrEMBL
BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST

BLAST of ER lumen protein-retaining receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KDELR2	2.071e-108	68.87	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	2.946e-100	64.45	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	1.635e-99	70.75	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	4.698e-94	64.18	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	6.054e-71	67.33	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
erd-2.1	4.125e-94	59.15	ER lumen protein-retaining receptor [Source:UniPr...	[more]
erd-2.2	2.375e-84	59.43	Putative ER lumen protein-retaining receptor C28H8...	[more]
erd-2.2	2.375e-84	59.43	Putative ER lumen protein-retaining receptor C28H8...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
KdelR	3.518e-112	69.81	gene:FBgn0267330 transcript:FBtr0080021	[more]
KdelR	3.518e-112	69.81	gene:FBgn0267330 transcript:FBtr0080023	[more]
KdelR	3.518e-112	69.81	gene:FBgn0267330 transcript:FBtr0080022	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kdelr2a	4.412e-109	70.28	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr2b	4.537e-108	69.81	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr3	4.237e-92	60.38	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr3	4.237e-92	60.38	KDEL endoplasmic reticulum protein retention recep...	[more]
CABZ01075611.1	3.679e-54	61.72	pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDA...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
kdelr1	9.586e-108	69.81	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr2	7.021e-107	68.87	KDEL endoplasmic reticulum protein retention recep...	[more]
stx1a	2.855e-89	61.57	syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753]	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kdelr2	1.407e-108	69.34	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr3	3.674e-101	63.21	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	1.028e-99	70.75	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	4.535e-71	67.33	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	3.446e-55	70.07	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]

BLAST of ER lumen protein-retaining receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O76767\|ERD2_DROME	3.527e-111	69.81	ER lumen protein-retaining receptor OS=Drosophila ...	[more]
sp\|Q6PEH1\|ERD22_DANRE	3.330e-108	70.28	ER lumen protein-retaining receptor 2 OS=Danio rer...	[more]
sp\|Q5ZKX9\|ERD22_CHICK	9.732e-108	69.34	ER lumen protein-retaining receptor 2 OS=Gallus ga...	[more]
sp\|Q5U305\|ERD22_RAT	9.839e-108	69.34	ER lumen protein-retaining receptor 2 OS=Rattus no...	[more]
sp\|Q9CQM2\|ERD22_MOUSE	9.839e-108	69.34	ER lumen protein-retaining receptor 2 OS=Mus muscu...	[more]

BLAST of ER lumen protein-retaining receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
B3MJH8	5.812e-110	71.70	ER lumen protein-retaining receptor OS=Drosophila ...	[more]
A0A1B6FB24	1.097e-109	70.28	ER lumen protein-retaining receptor OS=Cuerna arid...	[more]
A0A1B6JPH9	1.097e-109	70.28	ER lumen protein-retaining receptor OS=Homalodisca...	[more]
H2UVE4	1.523e-109	72.64	ER lumen protein-retaining receptor OS=Takifugu ru...	[more]
B4NZP5	2.750e-109	70.28	ER lumen protein-retaining receptor OS=Drosophila ...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kdelr2a	5.948e-110	70.28	ER lumen protein-retaining receptor 2-like [Source...	[more]
KDELR2	5.985e-109	70.28	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	4.514e-96	61.32	ER lumen protein-retaining receptor 3 [Source:NCBI...	[more]
ENSAMXT00000042346.1	9.635e-34	38.10	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000040094.1	2.894e-30	35.19	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
KDELR1	3.979e-102	69.34	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	6.495e-100	68.87	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
ERD2	2.350e-67	47.25	HDEL receptor; an integral membrane protein that b...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO48388	9.986e-111	68.40	ER lumen protein retaining receptor [Source:UniPr...	[more]

BLAST of ER lumen protein-retaining receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
KDELR2	1.297e-109	70.75	ER lumen protein-retaining receptor 2 [Source:NCBI...	[more]
kdelr2b	6.899e-108	69.34	ER lumen protein-retaining receptor 2 [Source:NCBI...	[more]
kdelr3	1.962e-95	62.26	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of ER lumen protein-retaining receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000073757.1	4.764e-145	100.00	SMESG000073757.1	[more]
SMESG000064394.1	2.631e-107	67.45	SMESG000064394.1	[more]
SMESG000053522.1	5.160e-93	62.56	SMESG000053522.1	[more]
SMESG000064394.1	1.045e-82	65.52	SMESG000064394.1	[more]
SMESG000064394.1	8.431e-68	69.63	SMESG000064394.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016810 ID=SMED30016810|Name=ER lumen protein-retaining receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=816bp
CTCGTTTTTTGAAATTTTATAAGTTTAAATTTTGGACACGTCCCTGTGTT
ATTTGATTTACTATCCAAGTTATCTTTAAGATGAATGCCTTTAGGTTTTT
AGGTGATATGTCTCATTTAATAGCTATAATTCTTTTGCTAAATAAAATAT
GGAAAAGCAGATCCTGTGCAGGTTTATCTGGAAAATCTCAAATAATGTTT
GCTGTAGTTTTTTTTACAAGATATTTGGATTTGTTTTTGGTTTATATATC
GCTTTACAATGTTTTAATGAAAGCTTTTTTTATTATTTCATCCCTTCTAA
CAGTTTATTTCATTTATTTCAAATTTAAAGCTACGTACGATTTAAATCAC
GATTCATTTAGATTAGAATTTATAATGGTTCCATTGGGTGGATTAGCAGT
TCTTATTAATCATAAATTTTCTTTTGTTGAAATTTTATGGACATATTCCA
TTTATCTTGAATCTCTTGCTATTTTGCCACAGTTATACCTAATTAGCAAA
ACTGGCGAGGCTGAAACAATTACGTCACATTATTTGTTTGCATTGGGAGT
CTATAGAGCATTTTATATTTTGAATTGGACTTATCGATTTTTTGTCGAAG
ATTTTTATGACTTAATCGCAATTTTTTCAGGAATTATTCAAACTATTCTT
TATTGCGACTTCTTTTATCTCTATATGACCAAAGTACTAAAGGGTAAAGC
ATTCACCTTACCTGCTTGAAAAAATGTGGAATATGATCTGAATTTGATCA
CAAGTCAATCAATGTTAATCAAAATCGTTATTTTATAACAAAATATTTAT
AAAGCAAATTTCTTTA

protein sequence of SMED30016810-orf-1

>SMED30016810-orf-1 ID=SMED30016810-orf-1|Name=SMED30016810-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=213bp
MNAFRFLGDMSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLD
LFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMV
PLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSH
YLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMT
KVLKGKAFTLPA*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000133	ER_ret_rcpt

Vocabulary: **molecular function**
Term	Definition
GO:0046923	ER retention sequence binding
GO:0005046	KDEL sequence binding

Vocabulary: **biological process**
Term	Definition
GO:0006621	protein retention in ER lumen
GO:0006810	transport
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0019233	sensory perception of pain

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0030140	trans-Golgi network transport vesicle

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000133	ER lumen protein retaining receptor	PRINTS	PR00660	ERLUMENR	coord: 142..156 score: 75.24 coord: 31..51 score: 68.03 coord: 52..68 score: 51.68 coord: 4..23 score: 65.0 coord: 156..174 score: 56.02 coord: 120..140 score: 69.39 coord: 184..199 score: 70.09
IPR000133	ER lumen protein retaining receptor	PFAM	PF00810	ER_lumen_recept	coord: 28..169 e-value: 5.1E-53 score: 179.8
IPR000133	ER lumen protein retaining receptor	PANTHER	PTHR10585	ER LUMEN PROTEIN RETAINING RECEPTOR	coord: 1..212
None	No IPR available	PANTHER	PTHR10585:SF37	ER LUMEN PROTEIN-RETAINING RECEPTOR 2	coord: 1..212
None	No IPR available	TMHMM	TMhelix		coord: 151..168
None	No IPR available	TMHMM	TMhelix		coord: 178..200
None	No IPR available	TMHMM	TMhelix		coord: 119..138
None	No IPR available	TMHMM	TMhelix		coord: 92..109
None	No IPR available	TMHMM	TMhelix		coord: 58..80