neurexin-1 isoform X19

Overview


Name	neurexin-1 isoform X19
Smed ID	SMED30016804
Length (bp)	4108

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of neurexin-1 isoform X19 (SMED30016804) t-SNE clustered cells

Violin plots show distribution of expression levels for neurexin-1 isoform X19 (SMED30016804) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of neurexin-1 isoform X19 (SMED30016804) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for neurexin-1 isoform X19 (SMED30016804) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016804

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30016804	h1SMcG0013788	SmedASXL_016975	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30016804	h1SMcG0013788	SmedASXL_004140	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30016804	h1SMcG0013788	dd_Smed_v4_13697_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016804	h1SMcG0013788	dd_Smed_v4_13697_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30016804	h1SMcG0013788	dd_Smed_v4_13697_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30016804	h1SMcG0013788	dd_Smed_v4_13697_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30016804	h1SMcG0013788	dd_Smed_v4_13697_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30016804	h1SMcG0013788	dd_Smed_v6_13697_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30016804	h1SMcG0013788	OX_Smed_1.0.07767	ox_Smed_v2	PMID:24238224 Kao et al., 2013
body wall musculature	SMED30016804	h1SMcG0013788	dd_Smed_v4_13697_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018

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Homology

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Human
Match: NRXN1 (neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008])

HSP 1 Score: 366.311 bits (939), Expect = 1.447e-104
Identity = 317/1236 (25.65%), Postives = 552/1236 (44.66%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYN-FSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQS----ILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKI-TTTPDNDIYTENTKSESSTIYK-SLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G+    FN Q TI +G      +  G+          F G LSGLY+N + + +M    + A I ++    +  E   +P+  + +S    + SE        T         +      EP+     + +D       I+       +  + I    P +      T++     Y  S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIG-----GKEQGQ---------PFQGQLSGLYYNGLKVLNMAAE-NDANIAIVGNVRLVGE---VPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPIS----QTTDD------ILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1445

HSP 2 Score: 125.561 bits (314), Expect = 3.571e-28
Identity = 205/899 (22.80%), Postives = 347/899 (38.60%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D  + K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEVQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 885

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Human
Match: NRXN1 (neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008])

HSP 1 Score: 357.451 bits (916), Expect = 2.073e-101
Identity = 321/1258 (25.52%), Postives = 557/1258 (44.28%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQS----ILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKI-TTTPDNDIYTENTKSESSTIYK-SLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M    + A I ++    +  E   +P+  + +S    + SE        T         +      EP+     + +D       I+       +  + I    P +      T++     Y  S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAE-NDANIAIVGNVRLVGE---VPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPIS----QTTDD------ILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1475

HSP 2 Score: 126.716 bits (317), Expect = 1.865e-28
Identity = 205/899 (22.80%), Postives = 347/899 (38.60%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D  + K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEVQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 885

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Human
Match: NRXN3 (neurexin 3 [Source:HGNC Symbol;Acc:HGNC:8010])

HSP 1 Score: 353.214 bits (905), Expect = 1.926e-100
Identity = 289/1074 (26.91%), Postives = 493/1074 (45.90%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDI-----LAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFL-GSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            VATF    Y+ Y+    P  S  D I L FKT Q    I + G           Y+ + L D  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D      ++      NF GC+++++Y  ++  L++     +A  K+K Y    GE+ F KC ++  + PI+F T  +YI+L  W   + G + F F+T E N L+ +       +K   SQ N + DF+A E+ +  L+  ++ GSG  + K +    +DG  ++V +  +  +  + +++ +     +   + LD   D+Y+GG+PE      LP  LW+ +L  G+VGC+ D+ ++G   ++   AE +N  G+ S CS     +  C + PC +   C  G+NRFICDC+ T Y G TC R A ++ ++G   M I MP    +E EDV+ RF++ R  G+ + T SR S  + RLE  L+ G++ +++N G+G + + +     D  WHT+++ RR  S+ L +DD   +    G    L    I  G     ++       F G++    FNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   +  ++DN WH V++ R+NS + S   ++D++ +      ++  G  N +   +L++ G A+   S   ++   V S  GF+GC++S  +N            +L+  AL  +G +E   E  +   +C+ + C + G C+QQW    CDC+MT++ G +C+    T  F      ++Y        +T  D LA G  T+V     + +    G   DF+   + + K    + + +N+G+    + E    + DG YH V F RNG  A+LQ+D++      P G T    N++  +   K PF   R       +K      F++              F G LSGLY++ + + +M
Sbjct:  256 VATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSA-------DYVNLALKDGAVSLVIN---LGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLPGSPVSN------NFMGCLKEVVYKNNDIRLELSRLARIADTKMKIY----GEVVF-KCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQ--CDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLE--LDGGRVKLMVNLGKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIAD-PVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHS--LKVDTKVV-----TQVINGAKNLDLKGDLYMAGLAQGMYSNLPKL---VASRDGFQGCLASVDLN--------GRLPDLINDALHRSGQIERGCEGPS--TTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPG-LGDFLQLHIEQGK----IGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTD---NERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNM 1265

HSP 2 Score: 115.161 bits (287), Expect = 5.019e-25
Identity = 203/881 (23.04%), Postives = 337/881 (38.25%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSL-WSGI-LRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTD-KGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC----------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAKEESPSNIEVT---ATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRE--------NSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVG---KYPFPNQRTGRSVQNDKTF-----DSFSGYLSGLYFNRIPLSDMIDN--ISYAGIK 3348
            W  + +  L F FKT  S  LL Y           DF    + +    L FS++         +S+  V+D   H++ +  +     + LD + +          +D   DL++GG+P       P +L   G+    GF G +LD+     +  L              G  G   D +G C  RPC +G  C +      CDCS T Y G  C                 R   +  F G + +  ++  N  QS  +++TL F T + NG+ + T      ++D + + L++G +++++N G G    I+      F+ N WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++    ++ ++      +   E      PI+F +  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G L LL + G+G  K    + K +D  W+ V + R+        NS+ + F    +S+ +     + L  GGL  N    L L   E + +  N          G+ GCI   +++      +K++ Q  LA      GV   C      Q    P  C +   C   W R  CDC  T + G  C++ +  L + D   Y+   +    +T  ++++F   +       +     D       + RL  D GR  L++  NLG G   L  +   + D  +H V   R G    L +DD                +      VG   +  F N  TG  +  +K +      SF G+L  L FN +   D+  N  I Y  +K
Sbjct:   43 WDASTRSDLSFQFKTNVSTGLLLYLDDG----GVCDFLCLSLVDGRVQLRFSMDCAETAV---LSNKQVNDSSWHFLMVSRDRLRTVLMLDGEGQSGELQPQRPYMDVVSDLFLGGVP---TDIRPSALTLDGVQAMPGFKGLILDLKYGNSEPRLL-------------GSRGVQMDAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGKLCSEGLSHLMMSEQGRSKAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGK----SADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYL--GGLPENR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKNIRQ--LAEMQNAAGVKSSCSRMSAKQCDSYP--CKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSY-DGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSAD----TLRLELDGGRVKLMV--NLGKGPETLY-AGQKLNDNEWHTVRVVRRGKSLKLTVDD----------------DVAEGTMVGDHTRLEFHNIETG--IMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELK 849

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Human
Match: NRXN1 (neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008])

HSP 1 Score: 353.599 bits (906), Expect = 3.631e-100
Identity = 318/1258 (25.28%), Postives = 551/1258 (43.80%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQS----ILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKI-TTTPDNDIYTENTKSESSTIYK-SLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M    + A I ++    +  E   +P+  + +S    + SE        T         +      EP+     + +D       I+       +  + I    P +      T++     Y  S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAE-NDANIAIVGNVRLVGE---VPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPIS----QTTDD------ILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1467

HSP 2 Score: 130.954 bits (328), Expect = 7.602e-30
Identity = 202/891 (22.67%), Postives = 344/891 (38.61%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D  + K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEVQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 877

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Human
Match: NRXN1 (neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008])

HSP 1 Score: 353.599 bits (906), Expect = 4.084e-100
Identity = 316/1257 (25.14%), Postives = 549/1257 (43.68%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQS----ILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYK-SLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M    + A I ++    +  E   +P+  + +S    + SE        T         +      EP+     + +D   +           +   +  +  P        T++     Y  S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAE-NDANIAIVGNVRLVGE---VPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPIS----QTTDDILVASAECPSDDEDIDPCEPSSANP--------TRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1464

HSP 2 Score: 131.339 bits (329), Expect = 5.886e-30
Identity = 202/891 (22.67%), Postives = 344/891 (38.61%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D  + K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEVQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 877

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Celegans
Match: nrx-1 (NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2HAJ7])

HSP 1 Score: 271.937 bits (694), Expect = 7.297e-74
Identity = 277/1079 (25.67%), Postives = 462/1079 (42.82%), Query Frame = 1

Query:  232 TFLQDAYI-YN-SINIPTV--SDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSR--KKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANL---DILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDI----------IAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAE---PTKEFPISFPSVNSYIRLP--KID-MYGDFKLEFLIKTRNNKGSVLQLYGKSGDY---LILEIVHGYXXXXXXXX----XXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQP----IGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNL---LAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTS-IHFNQQRTIYVGKY----PFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNIS 3333
            TF  D ++ Y+ S+NI     +  + + L FKT    S +FY G + S       Y+ + L D  +    K D       ++          D+ WHTI + R  +  SE+  +  + + V      +      L     IS S  F G IP        +   S   N  +F+GCM+K+ Y  D   +   ++  Q+       T G+I +   +       +SFT  +SY+TL  W     G L F F+T  S+ L+ Y      Q N  D+ AFE+ +S L   IN GSGV + + +S  VSDG  H+V+L        V +DA K    T  +   L     ++IG +P   + + P S+WS  L++G+ GC+ +I +NG    +  + E+ N TGI  GCS    +  +C   PC + G+C    N F CDCS TN+ G  C      V+ NG +  +  + +   S+ E + +RF TT   G+   T +  +G +D++ +FL + +LN+ L     N       +  D +WH L+++R    ++L +D       F   S  L N I           +V          +F G++    FNG +Y    K  S    + ++     +    T+   ISF +   Y+     KI  + G F+++F  +T   + ++L       DY     L++++G L   +       +  + K+     + D  WH V LI ++ K+      +D+      I +   +E K  G        L+ GS    +S+          S GF GCIS+  +N+        +Y++    + +    +G +  C ED           C + GRCIQ W  IRCDC++T   G+RC   S T++F+  P+ + Y+ +P +  T  +  F         + +++        D+ +  L K      L   YNLG+        +  + DGF H +   R     ++Q+D    +   PK  +  +  N Q  I +G          +R  R  +N + FDS+ G +SG+  N + + D+ +N S
Sbjct:  273 TFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS-------YLHVMLQDGAIIASSKFDGSDARIIRMFNSFPSQRYDDDSWHTIILERSLQMHSEEMVAIHMTLIVDGRRDEIRQYAPELD---WISNSFGFLGSIP--------KHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHG--VMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIIDDPIFIGNVPNNSLVY-PSSVWSIALQKGYTGCIKNIRMNGVSTKIGQEFEASNSTGIELGCSLS-NELDICEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVNGEESKVHVLAHTKVSQVEHIKIRFRTTSSRGVLFDTGA--NGKNDKITVFLNDSQLNLFLQDSSTNNTFSWGKSLSDNHWHELQVRRLGQKLLLYLD------GFWSHSIYLQNPISVEIDEVGAAFSVHSSAPPPRDEHFKGFLSKLVFNGNDYLAKTKMNSAQLSKSSSRESKGQRNVKTRIASISFTNSTGYVAFSSDKISGLTGSFRVQFKFQTLM-RSALLFFTLPKHDYDQSFRLQMLNGRLKYTYRTSGQEFHTTSPKLPHRQHLSDMRWHNV-LIYQDEKTHDHVLLVDNSSTTLIIDKIKKVESKMSG-------KLYFGSNPLGVSR---------PSNGFRGCISTLRINENAL----DLYEDADSRMKVNRGCSGPIARCIED----------ACANHGRCIQLWSSIRCDCSLTAHSGDRCQNPSTTVRFDGSPSAIFYEYAPNERPTTSKDYFVFSFRTTQPNGVLISIECAADQDYFTIFLNK----GYLNAHYNLGNRDHTTSYHTRILNDGFPHVIKISRTEANMTIQVDKLPSLRYRPKRASDLVLLNMQTRISIGAAFNTRHLDQKRLLRHRRNTEIFDSYQGEISGVNVNGLMILDLYENGS 1285

HSP 2 Score: 87.8113 bits (216), Expect = 5.199e-17
Identity = 149/704 (21.16%), Postives = 280/704 (39.77%), Query Frame = 1

Query:  895 SYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQK-------VSSTPVSDGLSHYVKLWFEDGNVEVQLDAD---KKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITG--IVSGCSGDVTDKGLCANRP--------CM-DGRCIIGYNRFICDCSRTNYTGDTC--GRVAPLVKFNGFQ----QMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF-GRGNKIIRSDYNCF------DGNWHTLKLKRR---------QLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKFSR-----YFTGYM--MHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFP------ISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQ---LYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF--AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN 2814
            SY     WA + +  L    KT +S+ +L Y     +  N   FY+  I E    L F +   S  + Q+       +    + D   H + ++    NV+++LD     K +   + ++  +    D++IGG+P  +   LP  + S  LR+      +++       +L  +   + +T   ++        +   C ++         C+ DG C    +   CDC  +++ G  C   +    + F G +     + +N+    +++ E++TL F T     +        S     L + L++G +     F G   +IIR  +N F      D +WHT+ L+R           + + LI+D    +   ++     +SN    +G       S+      F G M  + +  +      +   +      V  T GD   + + P      +SF   +SY+ LP+ +      L F  +T ++ G +L    +   + DY+  E++  +L ++ N G+G  +     +K+ D  WH V L R +   S    A +ID    G  A++ +          + +F+G+              +   +G+ GCI +  MN    VSTK + Q   A    + G+   C   +   + C PN C + G+C +      CDC+ T F G++C+     ++ N
Sbjct:   37 SYARYPKWAHSFENSLSMELKTRQSDGMLLYTDDGGTHGN---FYSLTIVEGHIQLDFRLGDNSNEFGQRRPVNTIRIEEVRIDDDKWHTLTIFQSWENVKLELDYTLVFKILNQRSFVFGNILKNSDVFIGGLPPNM-HMLP--VMSSPLRRYARHLAVNVR------NLMYRQYPQGVTSPQLLESVGTRTNEDDHCKSKSMSSREQFVCLNDGECYSSNDGPHCDCQFSDHDGRNCEIEKNDGELTFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS----YLHVMLQDGAIIASSKFDGSDARIIRM-FNSFPSQRYDDDSWHTIILERSLQMHSEEMVAIHMTLIVDGRRDEIRQYAPELDWISNSFGFLGSIPKHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHGVMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIID---------DPIFIGNVPNNSLVYPSSVWSIALQKGYTGCIKNIRMNG---VSTK-IGQEFEAS--NSTGIELGCSLSNELDI-CEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVN 707

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Celegans
Match: nrx-1 (NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2HAJ7])

HSP 1 Score: 271.166 bits (692), Expect = 1.738e-73
Identity = 277/1079 (25.67%), Postives = 462/1079 (42.82%), Query Frame = 1

Query:  232 TFLQDAYI-YN-SINIPTV--SDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSR--KKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANL---DILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDI----------IAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAE---PTKEFPISFPSVNSYIRLP--KID-MYGDFKLEFLIKTRNNKGSVLQLYGKSGDY---LILEIVHGYXXXXXXXX----XXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQP----IGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNL---LAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTS-IHFNQQRTIYVGKY----PFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNIS 3333
            TF  D ++ Y+ S+NI     +  + + L FKT    S +FY G + S       Y+ + L D  +    K D       ++          D+ WHTI + R  +  SE+  +  + + V      +      L     IS S  F G IP        +   S   N  +F+GCM+K+ Y  D   +   ++  Q+       T G+I +   +       +SFT  +SY+TL  W     G L F F+T  S+ L+ Y      Q N  D+ AFE+ +S L   IN GSGV + + +S  VSDG  H+V+L        V +DA K    T  +   L     ++IG +P   + + P S+WS  L++G+ GC+ +I +NG    +  + E+ N TGI  GCS    +  +C   PC + G+C    N F CDCS TN+ G  C      V+ NG +  +  + +   S+ E + +RF TT   G+   T +  +G +D++ +FL + +LN+ L     N       +  D +WH L+++R    ++L +D       F   S  L N I           +V          +F G++    FNG +Y    K  S    + ++     +    T+   ISF +   Y+     KI  + G F+++F  +T   + ++L       DY     L++++G L   +       +  + K+     + D  WH V LI ++ K+      +D+      I +   +E K  G        L+ GS    +S+          S GF GCIS+  +N+        +Y++    + +    +G +  C ED           C + GRCIQ W  IRCDC++T   G+RC   S T++F+  P+ + Y+ +P +  T  +  F         + +++        D+ +  L K      L   YNLG+        +  + DGF H +   R     ++Q+D    +   PK  +  +  N Q  I +G          +R  R  +N + FDS+ G +SG+  N + + D+ +N S
Sbjct:  273 TFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS-------YLHVMLQDGAIIASSKFDGSDARIIRMFNSFPSQRYDDDSWHTIILERSLQMHSEEMVAIHMTLIVDGRRDEIRQYAPELD---WISNSFGFLGSIP--------KHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHG--VMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIIDDPIFIGNVPNNSLVY-PSSVWSIALQKGYTGCIKNIRMNGVSTKIGQEFEASNSTGIELGCSLS-NELDICEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVNGEESKVHVLAHTKVSQVEHIKIRFRTTSSRGVLFDTGA--NGKNDKITVFLNDSQLNLFLQDSSTNNTFSWGKSLSDNHWHELQVRRLGQKLLLYLD------GFWSHSIYLQNPISVEIDEVGAAFSVHSSAPPPRDEHFKGFLSKLVFNGNDYLAKTKMNSAQLSKSSSRESKGQRNVKTRIASISFTNSTGYVAFSSDKISGLTGSFRVQFKFQTLM-RSALLFFTLPKHDYDQSFRLQMLNGRLKYTYRTSGQEFHTTSPKLPHRQHLSDMRWHNV-LIYQDEKTHDHVLLVDNSSTTLIIDKIKKVESKMSG-------KLYFGSNPLGVSR---------PSNGFRGCISTLRINENAL----DLYEDADSRMKVNRGCSGPIARCIED----------ACANHGRCIQLWSSIRCDCSLTAHSGDRCQNPSTTVRFDGSPSAIFYEYAPNERPTTSKDYFVFSFRTTQPNGVLISIECAADQDYFTIFLNK----GYLNAHYNLGNRDHTTSYHTRILNDGFPHVIKISRTEANMTIQVDKLPSLRYRPKRASDLVLLNMQTRISIGAAFNTRHLDQKRLLRHRRNTEIFDSYQGEISGVNVNGLMILDLYENGS 1285

HSP 2 Score: 87.4261 bits (215), Expect = 7.277e-17
Identity = 149/704 (21.16%), Postives = 280/704 (39.77%), Query Frame = 1

Query:  895 SYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQK-------VSSTPVSDGLSHYVKLWFEDGNVEVQLDAD---KKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITG--IVSGCSGDVTDKGLCANRP--------CM-DGRCIIGYNRFICDCSRTNYTGDTC--GRVAPLVKFNGFQ----QMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF-GRGNKIIRSDYNCF------DGNWHTLKLKRR---------QLSVILIIDDMEKK-YNFSGSSKLLSNDIIAVGKYETDKFSR-----YFTGYM--MHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFP------ISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQ---LYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF--AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN 2814
            SY     WA + +  L    KT +S+ +L Y     +  N   FY+  I E    L F +   S  + Q+       +    + D   H + ++    NV+++LD     K +   + ++  +    D++IGG+P  +   LP  + S  LR+      +++       +L  +   + +T   ++        +   C ++         C+ DG C    +   CDC  +++ G  C   +    + F G +     + +N+    +++ E++TL F T     +        S     L + L++G +     F G   +IIR  +N F      D +WHT+ L+R           + + LI+D    +   ++     +SN    +G       S+      F G M  + +  +      +   +      V  T GD   + + P      +SF   +SY+ LP+ +      L F  +T ++ G +L    +   + DY+  E++  +L ++ N G+G  +     +K+ D  WH V L R +   S    A +ID    G  A++ +          + +F+G+              +   +G+ GCI +  MN    VSTK + Q   A    + G+   C   +   + C PN C + G+C +      CDC+ T F G++C+     ++ N
Sbjct:   37 SYARYPKWAHSFENSLSMELKTRQSDGMLLYTDDGGTHGN---FYSLTIVEGHIQLDFRLGDNSNEFGQRRPVNTIRIEEVRIDDDKWHTLTIFQSWENVKLELDYTLVFKILNQRSFVFGNILKNSDVFIGGLPPNM-HMLP--VMSSPLRRYARHLAVNVR------NLMYRQYPQGVTSPQLLESVGTRTNEDDHCKSKSMSSREQFVCLNDGECYSSNDGPHCDCQFSDHDGRNCEIEKNDGELTFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS----YLHVMLQDGAIIASSKFDGSDARIIRM-FNSFPSQRYDDDSWHTIILERSLQMHSEEMVAIHMTLIVDGRRDEIRQYAPELDWISNSFGFLGSIPKHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHGVMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIID---------DPIFIGNVPNNSLVYPSSVWSIALQKGYTGCIKNIRMNG---VSTK-IGQEFEAS--NSTGIELGCSLSNELDI-CEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVN 707

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Celegans
Match: nrx-1 (NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2HAJ7])

HSP 1 Score: 270.396 bits (690), Expect = 2.488e-73
Identity = 274/1077 (25.44%), Postives = 457/1077 (42.43%), Query Frame = 1

Query:  232 TFLQDAYI-YN-SINIPTV--SDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANL---DILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDI----------IAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAE---PTKEFPISFPSVNSYIRLP--KID-MYGDFKLEFLIKTRNNKGSVLQLYGKSGDY---LILEIVHGYXXXXXXXX----XXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQP----IGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNL---LAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTS-IHFNQQRTIYVGKY----PFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNIS 3333
            TF  D ++ Y+ S+NI     +  + + L FKT    S +FY G + S       Y+ + L D  +    K D       ++          D+ WHTI + R           L +  ++      +          IS S  F G IP        +   S   N  +F+GCM+K+ Y  D   +   ++  Q+       T G+I +   +       +SFT  +SY+TL  W     G L F F+T  S+ L+ Y      Q N  D+ AFE+ +S L   IN GSGV + + +S  VSDG  H+V+L        V +DA K    T  +   L     ++IG +P   + + P S+WS  L++G+ GC+ +I +NG    +  + E+ N TGI  GCS    +  +C   PC + G+C    N F CDCS TN+ G  C      V+ NG +  +  + +   S+ E + +RF TT   G+   T +  +G +D++ +FL + +LN+ L     N       +  D +WH L+++R    ++L +D       F   S  L N I           +V          +F G++    FNG +Y    K  S    + ++     +    T+   ISF +   Y+     KI  + G F+++F  +T   + ++L       DY     L++++G L   +       +  + K+     + D  WH V LI ++ K+      +D+      I +   +E K  G        L+ GS    +S+          S GF GCIS+  +N+        +Y++    + +    +G +  C ED           C + GRCIQ W  IRCDC++T   G+RC   S T++F+  P+ + Y+ +P +  T  +  F         + +++        D+ +  L K      L   YNLG+        +  + DGF H +   R     ++Q+D    +   PK  +  +  N Q  I +G          +R  R  +N + FDS+ G +SG+  N + + D+ +N S
Sbjct:  273 TFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS-------YLHVMLQDGAIIASSKFDGSDARIIRMFNSFPSQRYDDDSWHTIILERS----------LQMMTLIVDGRRDEIRQYAPELDWISNSFGFLGSIP--------KHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHG--VMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIIDDPIFIGNVPNNSLVY-PSSVWSIALQKGYTGCIKNIRMNGVSTKIGQEFEASNSTGIELGCSLS-NELDICEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVNGEESKVHVLAHTKVSQVEHIKIRFRTTSSRGVLFDTGA--NGKNDKITVFLNDSQLNLFLQDSSTNNTFSWGKSLSDNHWHELQVRRLGQKLLLYLD------GFWSHSIYLQNPISVEIDEVGAAFSVHSSAPPPRDEHFKGFLSKLVFNGNDYLAKTKMNSAQLSKSSSRESKGQRNVKTRIASISFTNSTGYVAFSSDKISGLTGSFRVQFKFQTLM-RSALLFFTLPKHDYDQSFRLQMLNGRLKYTYRTSGQEFHTTSPKLPHRQHLSDMRWHNV-LIYQDEKTHDHVLLVDNSSTTLIIDKIKKVESKMSG-------KLYFGSNPLGVSR---------PSNGFRGCISTLRINENAL----DLYEDADSRMKVNRGCSGPIARCIED----------ACANHGRCIQLWSSIRCDCSLTAHSGDRCQNPSTTVRFDGSPSAIFYEYAPNERPTTSKDYFVFSFRTTQPNGVLISIECAADQDYFTIFLNK----GYLNAHYNLGNRDHTTSYHTRILNDGFPHVIKISRTEANMTIQVDKLPSLRYRPKRASDLVLLNMQTRISIGAAFNTRHLDQKRLLRHRRNTEIFDSYQGEISGVNVNGLMILDLYENGS 1276

HSP 2 Score: 92.8189 bits (229), Expect = 1.346e-18
Identity = 149/695 (21.44%), Postives = 279/695 (40.14%), Query Frame = 1

Query:  895 SYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQK-------VSSTPVSDGLSHYVKLWFEDGNVEVQLDAD---KKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITG--IVSGCSGDVTDKGLCANRP--------CM-DGRCIIGYNRFICDCSRTNYTGDTCG--RVAPLVKFNGFQ----QMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF-GRGNKIIRSDYNCF------DGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKFSR-----YFTGYM--MHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFP------ISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQ---LYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF--AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN 2814
            SY     WA + +  L    KT +S+ +L Y     +  N   FY+  I E    L F +   S  + Q+       +    + D   H + ++    NV+++LD     K +   + ++  +    D++IGG+P  +   LP  + S  LR+      +++       +L  +   + +T   ++        +   C ++         C+ DG C    +   CDC  +++ G  C   +    + F G +     + +N+    +++ E++TL F T     +        S     L + L++G +     F G   +IIR  +N F      D +WHT+ L+R    + LI+D    +   ++     +SN    +G       S+      F G M  + +  +      +   +      V  T GD   + + P      +SF   +SY+ LP+ +      L F  +T ++ G +L    +   + DY+  E++  +L ++ N G+G  +     +K+ D  WH V L R +   S    A +ID    G  A++ +          + +F+G+              +   +G+ GCI +  MN    VSTK + Q   A    + G+   C   +   + C PN C + G+C +      CDC+ T F G++C+     ++ N
Sbjct:   37 SYARYPKWAHSFENSLSMELKTRQSDGMLLYTDDGGTHGN---FYSLTIVEGHIQLDFRLGDNSNEFGQRRPVNTIRIEEVRIDDDKWHTLTIFQSWENVKLELDYTLVFKILNQRSFVFGNILKNSDVFIGGLPPNM-HMLP--VMSSPLRRYARHLAVNVR------NLMYRQYPQGVTSPQLLESVGTRTNEDDHCKSKSMSSREQFVCLNDGECYSSNDGPHCDCQFSDHDGRNCEIEKNDGELTFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS----YLHVMLQDGAIIASSKFDGSDARIIRM-FNSFPSQRYDDDSWHTIILERSLQMMTLIVDGRRDEIRQYAPELDWISNSFGFLGSIPKHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHGVMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIID---------DPIFIGNVPNNSLVYPSSVWSIALQKGYTGCIKNIRMNG---VSTK-IGQEFEAS--NSTGIELGCSLSNELDI-CEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVN 698

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Celegans
Match: nrx-1 (NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2HAJ7])

HSP 1 Score: 270.396 bits (690), Expect = 3.142e-73
Identity = 274/1077 (25.44%), Postives = 457/1077 (42.43%), Query Frame = 1

Query:  232 TFLQDAYI-YN-SINIPTV--SDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANL---DILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDI----------IAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAE---PTKEFPISFPSVNSYIRLP--KID-MYGDFKLEFLIKTRNNKGSVLQLYGKSGDY---LILEIVHGYXXXXXXXX----XXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQP----IGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNL---LAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTS-IHFNQQRTIYVGKY----PFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNIS 3333
            TF  D ++ Y+ S+NI     +  + + L FKT    S +FY G + S       Y+ + L D  +    K D       ++          D+ WHTI + R           L +  ++      +          IS S  F G IP        +   S   N  +F+GCM+K+ Y  D   +   ++  Q+       T G+I +   +       +SFT  +SY+TL  W     G L F F+T  S+ L+ Y      Q N  D+ AFE+ +S L   IN GSGV + + +S  VSDG  H+V+L        V +DA K    T  +   L     ++IG +P   + + P S+WS  L++G+ GC+ +I +NG    +  + E+ N TGI  GCS    +  +C   PC + G+C    N F CDCS TN+ G  C      V+ NG +  +  + +   S+ E + +RF TT   G+   T +  +G +D++ +FL + +LN+ L     N       +  D +WH L+++R    ++L +D       F   S  L N I           +V          +F G++    FNG +Y    K  S    + ++     +    T+   ISF +   Y+     KI  + G F+++F  +T   + ++L       DY     L++++G L   +       +  + K+     + D  WH V LI ++ K+      +D+      I +   +E K  G        L+ GS    +S+          S GF GCIS+  +N+        +Y++    + +    +G +  C ED           C + GRCIQ W  IRCDC++T   G+RC   S T++F+  P+ + Y+ +P +  T  +  F         + +++        D+ +  L K      L   YNLG+        +  + DGF H +   R     ++Q+D    +   PK  +  +  N Q  I +G          +R  R  +N + FDS+ G +SG+  N + + D+ +N S
Sbjct:  273 TFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS-------YLHVMLQDGAIIASSKFDGSDARIIRMFNSFPSQRYDDDSWHTIILERS----------LQMMTLIVDGRRDEIRQYAPELDWISNSFGFLGSIP--------KHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHG--VMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIIDDPIFIGNVPNNSLVY-PSSVWSIALQKGYTGCIKNIRMNGVSTKIGQEFEASNSTGIELGCSLS-NELDICEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVNGEESKVHVLAHTKVSQVEHIKIRFRTTSSRGVLFDTGA--NGKNDKITVFLNDSQLNLFLQDSSTNNTFSWGKSLSDNHWHELQVRRLGQKLLLYLD------GFWSHSIYLQNPISVEIDEVGAAFSVHSSAPPPRDEHFKGFLSKLVFNGNDYLAKTKMNSAQLSKSSSRESKGQRNVKTRIASISFTNSTGYVAFSSDKISGLTGSFRVQFKFQTLM-RSALLFFTLPKHDYDQSFRLQMLNGRLKYTYRTSGQEFHTTSPKLPHRQHLSDMRWHNV-LIYQDEKTHDHVLLVDNSSTTLIIDKIKKVESKMSG-------KLYFGSNPLGVSR---------PSNGFRGCISTLRINENAL----DLYEDADSRMKVNRGCSGPIARCIED----------ACANHGRCIQLWSSIRCDCSLTAHSGDRCQNPSTTVRFDGSPSAIFYEYAPNERPTTSKDYFVFSFRTTQPNGVLISIECAADQDYFTIFLNK----GYLNAHYNLGNRDHTTSYHTRILNDGFPHVIKISRTEANMTIQVDKLPSLRYRPKRASDLVLLNMQTRISIGAAFNTRHLDQKRLLRHRRNTEIFDSYQGEISGVNVNGLMILDLYENGS 1276

HSP 2 Score: 92.8189 bits (229), Expect = 1.442e-18
Identity = 149/695 (21.44%), Postives = 279/695 (40.14%), Query Frame = 1

Query:  895 SYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQK-------VSSTPVSDGLSHYVKLWFEDGNVEVQLDAD---KKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITG--IVSGCSGDVTDKGLCANRP--------CM-DGRCIIGYNRFICDCSRTNYTGDTCG--RVAPLVKFNGFQ----QMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF-GRGNKIIRSDYNCF------DGNWHTLKLKRRQLSVILIIDDMEKK-YNFSGSSKLLSNDIIAVGKYETDKFSR-----YFTGYM--MHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFP------ISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQ---LYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF--AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN 2814
            SY     WA + +  L    KT +S+ +L Y     +  N   FY+  I E    L F +   S  + Q+       +    + D   H + ++    NV+++LD     K +   + ++  +    D++IGG+P  +   LP  + S  LR+      +++       +L  +   + +T   ++        +   C ++         C+ DG C    +   CDC  +++ G  C   +    + F G +     + +N+    +++ E++TL F T     +        S     L + L++G +     F G   +IIR  +N F      D +WHT+ L+R    + LI+D    +   ++     +SN    +G       S+      F G M  + +  +      +   +      V  T GD   + + P      +SF   +SY+ LP+ +      L F  +T ++ G +L    +   + DY+  E++  +L ++ N G+G  +     +K+ D  WH V L R +   S    A +ID    G  A++ +          + +F+G+              +   +G+ GCI +  MN    VSTK + Q   A    + G+   C   +   + C PN C + G+C +      CDC+ T F G++C+     ++ N
Sbjct:   37 SYARYPKWAHSFENSLSMELKTRQSDGMLLYTDDGGTHGN---FYSLTIVEGHIQLDFRLGDNSNEFGQRRPVNTIRIEEVRIDDDKWHTLTIFQSWENVKLELDYTLVFKILNQRSFVFGNILKNSDVFIGGLPPNM-HMLP--VMSSPLRRYARHLAVNVR------NLMYRQYPQGVTSPQLLESVGTRTNEDDHCKSKSMSSREQFVCLNDGECYSSNDGPHCDCQFSDHDGRNCEIEKNDGELTFGGDEWVGYDVSLNISAAVRAKKENLTLTFKTVHGTSMLFYAGDEKS----YLHVMLQDGAIIASSKFDGSDARIIRM-FNSFPSQRYDDDSWHTIILERSLQMMTLIVDGRRDEIRQYAPELDWISNSFGFLGSIPKHNPSKEVNRVSFRGCMKKVRYDIDATRILLVNLADQSYGGSVVKTEGDISYSCKNPSQRSDVLSFTETSSYLTLPRWNSLSSGSLSFHFRTTSSDGLILYHGVMQHNATDYVAFELIDSHLFMIINLGSGVVRLQTTSMKVSDGEWHHVQLDRLSRTGSVIVDAIKIDFSTPGVSANLIID---------DPIFIGNVPNNSLVYPSSVWSIALQKGYTGCIKNIRMNG---VSTK-IGQEFEAS--NSTGIELGCSLSNELDI-CEPNPCQNFGKCSKNLNSFDCDCSNTNFEGKQCELEQTAVEVN 698

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Celegans
Match: unc-52 (Basement membrane proteoglycan [Source:UniProtKB/Swiss-Prot;Acc:Q06561])

HSP 1 Score: 62.3882 bits (150), Expect = 3.008e-9
Identity = 42/149 (28.19%), Postives = 65/149 (43.62%), Query Frame = 1

Query:  946 FSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIE---HTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKA 1383
            F FKT + N +L +Q    +     D+ +  I    LHFS   G G     +S   V DG  H V+  FE    E Q+  D   E    +  +   L+   ++++GG+P+            G+    FVGC+ D+ +NG + DL   A
Sbjct: 3211 FKFKTEQQNGVLLWQGQRPTVQQMEDYISVGIVNGHLHFSYELGGGA-AHLISEERVDDGKEHSVR--FERKGREGQMRIDNYREVDGRSTGILAMLNVDGNIFVGGVPDI------SKATGGLFSNNFVGCIADVELNGVKLDLMATA 3350

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Fly
Match: Nrx-1 (gene:FBgn0038975 transcript:FBtr0334611)

HSP 1 Score: 308.916 bits (790), Expect = 1.389e-85
Identity = 268/1054 (25.43%), Postives = 468/1054 (44.40%), Query Frame = 1

Query:  274 PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIK-HDRLPESTFKVTCVSIYSTCTDNRWHTISVSRK--KTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMI-PMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQK-SETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDG-RCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPN--GFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCF-DGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAV------GKYETDKFSRY------FTGYMMHFTFNGINYFELAKEESP-------SNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF----AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYM-NQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYV-GKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            P VS  DAI+  F+T+Q    +FY G        G  Y+ + L D  + + +   +   E   K + V       D++WH ++V R+  + S   S  +LV  V              T+  L S  +  GG + P       +          TNF GC++K+ +S D  NL+++  AK     +        +C       P++FTT  S++ L  W   ++  + F F+T E N ++     S+  +       A E+    ++  ++ GSG  + + S   V DG  H + L     + +V +D       T      L+    +Y+GG+     S   P ++W+  LRQGFVGCL D+ ++G   D+A  A  ++   +   C        +C   PC++G  C+ G+NR ICDCS T Y G TCGR    + FNG Q M I + N  G +++ E++ +RF T+RP G+ ++T +  S + DRLEI L  G++   +      K + +  +   D NWHT++  RR  ++ L +D           + L  +  + +      G +  ++  +       F G M    FNG  Y ++ K   P       +  ++TA   ++   + +   +F S +SY+ L  +  Y    ++F  KT    G ++   G+  D++ +E+V+G+++            + +  I ++DN WH+V + R   K+ +     +F I S   G   H+EL            L++G   K +   +++   ++S  GFEGC++S  + + +  +++ +V  + L        VV  C         C  N C + G C+QQW    C+C MT++ G  C   S   +F +    + Y    +   +T  D +A G  T+   +  + +        D++   +++      + + YN+GS    L E    + D  YH V F+R G  A+LQ+DDYN    +P+   S  FN    + V GK+     R GR    ++    F+G ++GL  N++ + D+
Sbjct:  374 PIVSAQDAISFYFRTRQPNGLLFYTGH-------GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRF----DDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTM--LSSSRVYVGGAVNPRALLGARVH---------TNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQDPVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGKAIDIAAFARVQDSASVKPSCH---VQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAE-SNSPDRLEIALVAGRVRASVRLSDREKNLLAGQSVLNDNNWHTIRFSRRASNLRLQVDGAPPVRGMLSETILGRHSTMEIRSVHLGGLFHAEEEIQMTSTMPNFVGQMQGLVFNGQRYLDIVKSLGPELSALPSATFKLTARFVNSPAGQPYHAATFRSKHSYVGLAMLKAYNSISIDFRFKTVEPNGLLVFNGGRRNDFVAVELVNGHIHYTFDLGDGPVTMRDKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIISL-TGNNMHLELAG---------ILYIGGVFKDM--YSKLPASISSRSGFEGCLASLDLGDASPSLTSDAVVPSSL--------VVSGC----EGPTKCSQNACANRGNCVQQWNAYACECDMTSYTGPTCYDESIAYEFGNNKGMVQYTFPENAQADTEEDNIALGFITTRPDAVLLRVES--ATTQDYMELEIVEGN----IFMVYNIGSVDLPLGEIGTKVNDNAYHVVRFQRKGGNATLQLDDYNVQALTPQSHHSTVFNTMSNVQVGGKF----SRNGR----NRIERPFAGVIAGLSVNKLRILDL 1363

HSP 2 Score: 133.65 bits (335), Expect = 5.460e-31
Identity = 199/890 (22.36%), Postives = 349/890 (39.21%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNS---LYKTLDTTRDLYIGGIPETLVSFLPH-SLWSGILRQGFVGCLLDISVNGDQFDLA-----------------------LKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCGR-VAPL-VKFNGFQQMIINM----PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNK---IIRSDYNCFDGNWHTLKLKRR--QLS-------VILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNG-------------INYFELAKEES-----PSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVL------QLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIR--ENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSS--QGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDC----PEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLII---EYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIA----SPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFN 3297
            ++ S+ T   W     G L+  FKT + N L+ Y    T     +DF+  ++ E  L    N G G  Q       + DG  H V++   D    + +D   +   T      +    +  D+Y+GG+P    S L   +L S I    F G + ++ V  DQ   +                       L A    + G+  G + D  ++    N PC  G  CI   +  IC+C    Y G  C +  AP    F G Q +  ++         S  + ++  F T +PNG+   T       +D L + L +G +++ +    G +   I  S     D  WH + + RR  ++S       ++ ++DD+   + + +G   +LS+  + VG        R   G  +H  F G             +N  +LAK  S       N+E     GD +     P++F +  S++ LP  +      + F  +T+   G ++      Q   K+   + +E+++G++ +  + G+G +K      ++DD  WH +IL R   ++K S      D +  G+   +EL           +++LG      +  +      T++  QGF GC+    ++               AI +A    V+D     P  H     C  N C +GG C++ W R  CDC+ T + G  C +   TL FN      I+  +     T  E       +   +  ++L   +    D +   L+  + RA + +   E NL +G     +S +N  D  +H + F R  +   LQ+D    +      +  G+ S    + R++++G      +     +Q   T  +F G + GL FN
Sbjct:  110 SQNSFYTFRKWYTGLNGTLELEFKTEQPNGLVLY----TDDGGTYDFFELKLVEGALRLRYNLGGGA-QIITVGRELHDGHWHKVQVLRNDEQTSLIVDGVSQQRSTKGKEFQFGKFASNSDVYVGGMPNWYSSKLALLALPSVIFEPRFRGAIRNL-VYADQPGGSTRRQEIKQQRDIKCGDVPCDHGELPARERPLRGVRGGNTTDACER----NDPCQHGGICISTDSGPICECRNLEYDGQYCEKEKAPSEATFRGTQFLSYDLGQTGAEPIVSAQDAISFYFRTRQPNGLLFYTGH----GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRFDDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTMLSSSRVYVGGAVN---PRALLGARVHTNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQD----PVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDG---------HMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGK-------------AIDIAAFARVQDSASVKPSCHVQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAESNSPDRLEIALVAGRVRASVRLSDREKNLLAG-----QSVLN--DNNWHTIRFSRRASNLRLQVDGAPPVRGMLSETILGRHSTM--EIRSVHLGGLFHAEEE----IQMTSTMPNFVGQMQGLVFN 943

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Fly
Match: Nrx-1 (gene:FBgn0038975 transcript:FBtr0334609)

HSP 1 Score: 309.301 bits (791), Expect = 1.919e-85
Identity = 270/1055 (25.59%), Postives = 473/1055 (44.83%), Query Frame = 1

Query:  274 PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIK-HDRLPESTFKVTCVSIYSTCTDNRWHTISVSRK--KTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMI-PMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKI-KRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQK-SETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDG-RCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPN--GFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCF-DGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAV------GKYETDKFSRY------FTGYMMHFTFNGINYFELAKEESP-------SNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF----AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYM-NQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYV-GKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            P VS  DAI+  F+T+Q    +FY G        G  Y+ + L D  + + +   +   E   K + V       D++WH ++V R+  + S   S  +LV  V              T+  L S  +  GG + P       +          TNF GC++K+ +S D  NL+++  AK   +     G + + +C       P++FTT  S++ L  W   ++  + F F+T E N ++     S+  +       A E+    ++  ++ GSG  + + S   V DG  H + L     + +V +D       T      L+    +Y+GG+     S   P ++W+  LRQGFVGCL D+ ++G   D+A  A  ++   +   C        +C   PC++G  C+ G+NR ICDCS T Y G TCGR    + FNG Q M I + N  G +++ E++ +RF T+RP G+ ++T +  S + DRLEI L  G++   +      K + +  +   D NWHT++  RR  ++ L +D           + L  +  + +      G +  ++  +       F G M    FNG  Y ++ K   P       +  ++TA   ++   + +   +F S +SY+ L  +  Y    ++F  KT    G ++   G+  D++ +E+V+G+++            + +  I ++DN WH+V + R   K+ +     +F I S   G   H+EL   G+       L++G   K +   +++   ++S  GFEGC++S  + + +  +++ +V  + L        VV  C         C  N C + G C+QQW    C+C MT++ G  C   S   +F +    + Y    +   +T  D +A G  T+   +  + +        D++   +++      + + YN+GS    L E    + D  YH V F+R G  A+LQ+DDYN    +P+   S  FN    + V GK+     R GR    ++    F+G ++GL  N++ + D+
Sbjct:  374 PIVSAQDAISFYFRTRQPNGLLFYTGH-------GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRF----DDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTM--LSSSRVYVGGAVNPRALLGARVH---------TNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEY-QCPSGDPQDPVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGKAIDIAAFARVQDSASVKPSCH---VQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAE-SNSPDRLEIALVAGRVRASVRLSDREKNLLAGQSVLNDNNWHTIRFSRRASNLRLQVDGAPPVRGMLSETILGRHSTMEIRSVHLGGLFHAEEEIQMTSTMPNFVGQMQGLVFNGQRYLDIVKSLGPELSALPSATFKLTARFVNSPAGQPYHAATFRSKHSYVGLAMLKAYNSISIDFRFKTVEPNGLLVFNGGRRNDFVAVELVNGHIHYTFDLGDGPVTMRDKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIISL-TGNNMHLEL--AGI-------LYIGGVFKDM--YSKLPASISSRSGFEGCLASLDLGDASPSLTSDAVVPSSL--------VVSGC----EGPTKCSQNACANRGNCVQQWNAYACECDMTSYTGPTCYDESIAYEFGNNKGMVQYTFPENAQADTEEDNIALGFITTRPDAVLLRVES--ATTQDYMELEIVEGN----IFMVYNIGSVDLPLGEIGTKVNDNAYHVVRFQRKGGNATLQLDDYNVQALTPQSHHSTVFNTMSNVQVGGKF----SRNGR----NRIERPFAGVIAGLSVNKLRILDL 1363

HSP 2 Score: 133.65 bits (335), Expect = 7.390e-31
Identity = 202/893 (22.62%), Postives = 350/893 (39.19%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNS---LYKTLDTTRDLYIGGIPETLVSFLPH-SLWSGILRQGFVGCLLDISVNGDQFDLA-----------------------LKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCGR-VAPL-VKFNGFQQMIINM----PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNK---IIRSDYNCFDGNWHTLKLKRR--QLS-------VILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNG-------------INYFELAKEES-----PSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVL------QLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIR--ENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSS--QGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDC----PEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLII---EYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASP-KGKTS-----IHFNQQ-RTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFN 3297
            ++ S+ T   W     G L+  FKT + N L+ Y    T     +DF+  ++ E  L    N G G  Q       + DG  H V++   D    + +D   +   T      +    +  D+Y+GG+P    S L   +L S I    F G + ++ V  DQ   +                       L A    + G+  G + D  ++    N PC  G  CI   +  IC+C    Y G  C +  AP    F G Q +  ++         S  + ++  F T +PNG+   T       +D L + L +G +++ +    G +   I  S     D  WH + + RR  ++S       ++ ++DD+   + + +G   +LS+  + VG        R   G  +H  F G             +N  +LAK  S       N+E     GD +     P++F +  S++ LP  +      + F  +T+   G ++      Q   K+   + +E+++G++ +  + G+G +K      ++DD  WH +IL R   ++K S      D +  G+   +EL           +++LG      +  +      T++  QGF GC+    ++               AI +A    V+D     P  H     C  N C +GG C++ W R  CDC+ T + G  C +   TL FN      I+  +     T  E       +   +  ++L   +    D +   L+  + RA + +   E NL +G     +S +N  D  +H + F R  +   LQ+D      A P +G  S      H   + R++++G      +     +Q   T  +F G + GL FN
Sbjct:  110 SQNSFYTFRKWYTGLNGTLELEFKTEQPNGLVLY----TDDGGTYDFFELKLVEGALRLRYNLGGGA-QIITVGRELHDGHWHKVQVLRNDEQTSLIVDGVSQQRSTKGKEFQFGKFASNSDVYVGGMPNWYSSKLALLALPSVIFEPRFRGAIRNL-VYADQPGGSTRRQEIKQQRDIKCGDVPCDHGELPARERPLRGVRGGNTTDACER----NDPCQHGGICISTDSGPICECRNLEYDGQYCEKEKAPSEATFRGTQFLSYDLGQTGAEPIVSAQDAISFYFRTRQPNGLLFYTGH----GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRFDDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTMLSSSRVYVGGAVN---PRALLGARVHTNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQD----PVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDG---------HMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGK-------------AIDIAAFARVQDSASVKPSCHVQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAESNSPDRLEIALVAGRVRASVRLSDREKNLLAG-----QSVLN--DNNWHTIRFSRRASNLRLQVDG-----APPVRGMLSETILGRHSTMEIRSVHLGGLFHAEE----EIQMTSTMPNFVGQMQGLVFN 943

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Fly
Match: Nrx-1 (gene:FBgn0038975 transcript:FBtr0334610)

HSP 1 Score: 308.916 bits (790), Expect = 2.656e-85
Identity = 270/1055 (25.59%), Postives = 473/1055 (44.83%), Query Frame = 1

Query:  274 PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIK-HDRLPESTFKVTCVSIYSTCTDNRWHTISVSRK--KTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMI-PMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKI-KRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQK-SETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDG-RCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPN--GFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCF-DGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAV------GKYETDKFSRY------FTGYMMHFTFNGINYFELAKEESP-------SNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF----AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYM-NQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYV-GKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            P VS  DAI+  F+T+Q    +FY G        G  Y+ + L D  + + +   +   E   K + V       D++WH ++V R+  + S   S  +LV  V              T+  L S  +  GG + P       +          TNF GC++K+ +S D  NL+++  AK   +     G + + +C       P++FTT  S++ L  W   ++  + F F+T E N ++     S+  +       A E+    ++  ++ GSG  + + S   V DG  H + L     + +V +D       T      L+    +Y+GG+     S   P ++W+  LRQGFVGCL D+ ++G   D+A  A  ++   +   C        +C   PC++G  C+ G+NR ICDCS T Y G TCGR    + FNG Q M I + N  G +++ E++ +RF T+RP G+ ++T +  S + DRLEI L  G++   +      K + +  +   D NWHT++  RR  ++ L +D           + L  +  + +      G +  ++  +       F G M    FNG  Y ++ K   P       +  ++TA   ++   + +   +F S +SY+ L  +  Y    ++F  KT    G ++   G+  D++ +E+V+G+++            + +  I ++DN WH+V + R   K+ +     +F I S   G   H+EL   G+       L++G   K +   +++   ++S  GFEGC++S  + + +  +++ +V  + L        VV  C         C  N C + G C+QQW    C+C MT++ G  C   S   +F +    + Y    +   +T  D +A G  T+   +  + +        D++   +++      + + YN+GS    L E    + D  YH V F+R G  A+LQ+DDYN    +P+   S  FN    + V GK+     R GR    ++    F+G ++GL  N++ + D+
Sbjct:  374 PIVSAQDAISFYFRTRQPNGLLFYTGH-------GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRF----DDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTM--LSSSRVYVGGAVNPRALLGARVH---------TNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEY-QCPSGDPQDPVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGKAIDIAAFARVQDSASVKPSCH---VQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAE-SNSPDRLEIALVAGRVRASVRLSDREKNLLAGQSVLNDNNWHTIRFSRRASNLRLQVDGAPPVRGMLSETILGRHSTMEIRSVHLGGLFHAEEEIQMTSTMPNFVGQMQGLVFNGQRYLDIVKSLGPELSALPSATFKLTARFVNSPAGQPYHAATFRSKHSYVGLAMLKAYNSISIDFRFKTVEPNGLLVFNGGRRNDFVAVELVNGHIHYTFDLGDGPVTMRDKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIISL-TGNNMHLEL--AGI-------LYIGGVFKDM--YSKLPASISSRSGFEGCLASLDLGDASPSLTSDAVVPSSL--------VVSGC----EGPTKCSQNACANRGNCVQQWNAYACECDMTSYTGPTCYDESIAYEFGNNKGMVQYTFPENAQADTEEDNIALGFITTRPDAVLLRVES--ATTQDYMELEIVEGN----IFMVYNIGSVDLPLGEIGTKVNDNAYHVVRFQRKGGNATLQLDDYNVQALTPQSHHSTVFNTMSNVQVGGKF----SRNGR----NRIERPFAGVIAGLSVNKLRILDL 1363

HSP 2 Score: 133.265 bits (334), Expect = 8.729e-31
Identity = 202/893 (22.62%), Postives = 350/893 (39.19%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNS---LYKTLDTTRDLYIGGIPETLVSFLPH-SLWSGILRQGFVGCLLDISVNGDQFDLA-----------------------LKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCGR-VAPL-VKFNGFQQMIINM----PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNK---IIRSDYNCFDGNWHTLKLKRR--QLS-------VILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNG-------------INYFELAKEES-----PSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVL------QLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIR--ENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSS--QGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDC----PEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLII---EYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASP-KGKTS-----IHFNQQ-RTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFN 3297
            ++ S+ T   W     G L+  FKT + N L+ Y    T     +DF+  ++ E  L    N G G  Q       + DG  H V++   D    + +D   +   T      +    +  D+Y+GG+P    S L   +L S I    F G + ++ V  DQ   +                       L A    + G+  G + D  ++    N PC  G  CI   +  IC+C    Y G  C +  AP    F G Q +  ++         S  + ++  F T +PNG+   T       +D L + L +G +++ +    G +   I  S     D  WH + + RR  ++S       ++ ++DD+   + + +G   +LS+  + VG        R   G  +H  F G             +N  +LAK  S       N+E     GD +     P++F +  S++ LP  +      + F  +T+   G ++      Q   K+   + +E+++G++ +  + G+G +K      ++DD  WH +IL R   ++K S      D +  G+   +EL           +++LG      +  +      T++  QGF GC+    ++               AI +A    V+D     P  H     C  N C +GG C++ W R  CDC+ T + G  C +   TL FN      I+  +     T  E       +   +  ++L   +    D +   L+  + RA + +   E NL +G     +S +N  D  +H + F R  +   LQ+D      A P +G  S      H   + R++++G      +     +Q   T  +F G + GL FN
Sbjct:  110 SQNSFYTFRKWYTGLNGTLELEFKTEQPNGLVLY----TDDGGTYDFFELKLVEGALRLRYNLGGGA-QIITVGRELHDGHWHKVQVLRNDEQTSLIVDGVSQQRSTKGKEFQFGKFASNSDVYVGGMPNWYSSKLALLALPSVIFEPRFRGAIRNL-VYADQPGGSTRRQEIKQQRDIKCGDVPCDHGELPARERPLRGVRGGNTTDACER----NDPCQHGGICISTDSGPICECRNLEYDGQYCEKEKAPSEATFRGTQFLSYDLGQTGAEPIVSAQDAISFYFRTRQPNGLLFYTGH----GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRFDDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTMLSSSRVYVGGAVN---PRALLGARVHTNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQD----PVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDG---------HMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGK-------------AIDIAAFARVQDSASVKPSCHVQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAESNSPDRLEIALVAGRVRASVRLSDREKNLLAG-----QSVLN--DNNWHTIRFSRRASNLRLQVDG-----APPVRGMLSETILGRHSTMEIRSVHLGGLFHAEE----EIQMTSTMPNFVGQMQGLVFN 943

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Fly
Match: Nrx-1 (gene:FBgn0038975 transcript:FBtr0334612)

HSP 1 Score: 308.916 bits (790), Expect = 2.684e-85
Identity = 269/1054 (25.52%), Postives = 470/1054 (44.59%), Query Frame = 1

Query:  274 PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIK-HDRLPESTFKVTCVSIYSTCTDNRWHTISVSRK--KTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMI-PMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQK-SETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDG-RCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPN--GFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCF-DGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAV------GKYETDKFSRY------FTGYMMHFTFNGINYFELAKEESP-------SNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF----AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYM-NQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYV-GKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            P VS  DAI+  F+T+Q    +FY G        G  Y+ + L D  + + +   +   E   K + V       D++WH ++V R+  + S   S  +LV  V              T+  L S  +  GG + P       +          TNF GC++K+ +S D  NL+++  AK     +        +C       P++FTT  S++ L  W   ++  + F F+T E N ++     S+  +       A E+    ++  ++ GSG  + + S   V DG  H + L     + +V +D       T      L+    +Y+GG+     S   P ++W+  LRQGFVGCL D+ ++G   D+A  A  ++   +   C        +C   PC++G  C+ G+NR ICDCS T Y G TCGR    + FNG Q M I + N  G +++ E++ +RF T+RP G+ ++T +  S + DRLEI L  G++   +      K + +  +   D NWHT++  RR  ++ L +D           + L  +  + +      G +  ++  +       F G M    FNG  Y ++ K   P       +  ++TA   ++   + +   +F S +SY+ L  +  Y    ++F  KT    G ++   G+  D++ +E+V+G+++            + +  I ++DN WH+V + R   K+ +     +F I S   G   H+EL   G+       L++G   K +   +++   ++S  GFEGC++S  + + +  +++ +V  + L        VV  C         C  N C + G C+QQW    C+C MT++ G  C   S   +F +    + Y    +   +T  D +A G  T+   +  + +        D++   +++      + + YN+GS    L E    + D  YH V F+R G  A+LQ+DDYN    +P+   S  FN    + V GK+     R GR    ++    F+G ++GL  N++ + D+
Sbjct:  374 PIVSAQDAISFYFRTRQPNGLLFYTGH-------GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRF----DDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTM--LSSSRVYVGGAVNPRALLGARVH---------TNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQDPVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGKAIDIAAFARVQDSASVKPSCH---VQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAE-SNSPDRLEIALVAGRVRASVRLSDREKNLLAGQSVLNDNNWHTIRFSRRASNLRLQVDGAPPVRGMLSETILGRHSTMEIRSVHLGGLFHAEEEIQMTSTMPNFVGQMQGLVFNGQRYLDIVKSLGPELSALPSATFKLTARFVNSPAGQPYHAATFRSKHSYVGLAMLKAYNSISIDFRFKTVEPNGLLVFNGGRRNDFVAVELVNGHIHYTFDLGDGPVTMRDKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIISL-TGNNMHLEL--AGI-------LYIGGVFKDM--YSKLPASISSRSGFEGCLASLDLGDASPSLTSDAVVPSSL--------VVSGC----EGPTKCSQNACANRGNCVQQWNAYACECDMTSYTGPTCYDESIAYEFGNNKGMVQYTFPENAQADTEEDNIALGFITTRPDAVLLRVES--ATTQDYMELEIVEGN----IFMVYNIGSVDLPLGEIGTKVNDNAYHVVRFQRKGGNATLQLDDYNVQALTPQSHHSTVFNTMSNVQVGGKF----SRNGR----NRIERPFAGVIAGLSVNKLRILDL 1363

HSP 2 Score: 133.265 bits (334), Expect = 9.977e-31
Identity = 202/893 (22.62%), Postives = 350/893 (39.19%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNS---LYKTLDTTRDLYIGGIPETLVSFLPH-SLWSGILRQGFVGCLLDISVNGDQFDLA-----------------------LKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCGR-VAPL-VKFNGFQQMIINM----PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNK---IIRSDYNCFDGNWHTLKLKRR--QLS-------VILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNG-------------INYFELAKEES-----PSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVL------QLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIR--ENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSS--QGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDC----PEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLII---EYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASP-KGKTS-----IHFNQQ-RTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFN 3297
            ++ S+ T   W     G L+  FKT + N L+ Y    T     +DF+  ++ E  L    N G G  Q       + DG  H V++   D    + +D   +   T      +    +  D+Y+GG+P    S L   +L S I    F G + ++ V  DQ   +                       L A    + G+  G + D  ++    N PC  G  CI   +  IC+C    Y G  C +  AP    F G Q +  ++         S  + ++  F T +PNG+   T       +D L + L +G +++ +    G +   I  S     D  WH + + RR  ++S       ++ ++DD+   + + +G   +LS+  + VG        R   G  +H  F G             +N  +LAK  S       N+E     GD +     P++F +  S++ LP  +      + F  +T+   G ++      Q   K+   + +E+++G++ +  + G+G +K      ++DD  WH +IL R   ++K S      D +  G+   +EL           +++LG      +  +      T++  QGF GC+    ++               AI +A    V+D     P  H     C  N C +GG C++ W R  CDC+ T + G  C +   TL FN      I+  +     T  E       +   +  ++L   +    D +   L+  + RA + +   E NL +G     +S +N  D  +H + F R  +   LQ+D      A P +G  S      H   + R++++G      +     +Q   T  +F G + GL FN
Sbjct:  110 SQNSFYTFRKWYTGLNGTLELEFKTEQPNGLVLY----TDDGGTYDFFELKLVEGALRLRYNLGGGA-QIITVGRELHDGHWHKVQVLRNDEQTSLIVDGVSQQRSTKGKEFQFGKFASNSDVYVGGMPNWYSSKLALLALPSVIFEPRFRGAIRNL-VYADQPGGSTRRQEIKQQRDIKCGDVPCDHGELPARERPLRGVRGGNTTDACER----NDPCQHGGICISTDSGPICECRNLEYDGQYCEKEKAPSEATFRGTQFLSYDLGQTGAEPIVSAQDAISFYFRTRQPNGLLFYTGH----GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRFDDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTMLSSSRVYVGGAVN---PRALLGARVHTNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQD----PVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDG---------HMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGK-------------AIDIAAFARVQDSASVKPSCHVQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAESNSPDRLEIALVAGRVRASVRLSDREKNLLAG-----QSVLN--DNNWHTIRFSRRASNLRLQVDG-----APPVRGMLSETILGRHSTMEIRSVHLGGLFHAEE----EIQMTSTMPNFVGQMQGLVFN 943

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Fly
Match: Nrx-1 (gene:FBgn0038975 transcript:FBtr0334608)

HSP 1 Score: 308.916 bits (790), Expect = 2.684e-85
Identity = 269/1054 (25.52%), Postives = 470/1054 (44.59%), Query Frame = 1

Query:  274 PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIK-HDRLPESTFKVTCVSIYSTCTDNRWHTISVSRK--KTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMI-PMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQK-SETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDG-RCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPN--GFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCF-DGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAV------GKYETDKFSRY------FTGYMMHFTFNGINYFELAKEESP-------SNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSF----AFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYM-NQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYV-GKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            P VS  DAI+  F+T+Q    +FY G        G  Y+ + L D  + + +   +   E   K + V       D++WH ++V R+  + S   S  +LV  V              T+  L S  +  GG + P       +          TNF GC++K+ +S D  NL+++  AK     +        +C       P++FTT  S++ L  W   ++  + F F+T E N ++     S+  +       A E+    ++  ++ GSG  + + S   V DG  H + L     + +V +D       T      L+    +Y+GG+     S   P ++W+  LRQGFVGCL D+ ++G   D+A  A  ++   +   C        +C   PC++G  C+ G+NR ICDCS T Y G TCGR    + FNG Q M I + N  G +++ E++ +RF T+RP G+ ++T +  S + DRLEI L  G++   +      K + +  +   D NWHT++  RR  ++ L +D           + L  +  + +      G +  ++  +       F G M    FNG  Y ++ K   P       +  ++TA   ++   + +   +F S +SY+ L  +  Y    ++F  KT    G ++   G+  D++ +E+V+G+++            + +  I ++DN WH+V + R   K+ +     +F I S   G   H+EL   G+       L++G   K +   +++   ++S  GFEGC++S  + + +  +++ +V  + L        VV  C         C  N C + G C+QQW    C+C MT++ G  C   S   +F +    + Y    +   +T  D +A G  T+   +  + +        D++   +++      + + YN+GS    L E    + D  YH V F+R G  A+LQ+DDYN    +P+   S  FN    + V GK+     R GR    ++    F+G ++GL  N++ + D+
Sbjct:  374 PIVSAQDAISFYFRTRQPNGLLFYTGH-------GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRF----DDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTM--LSSSRVYVGGAVNPRALLGARVH---------TNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQDPVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGKAIDIAAFARVQDSASVKPSCH---VQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAE-SNSPDRLEIALVAGRVRASVRLSDREKNLLAGQSVLNDNNWHTIRFSRRASNLRLQVDGAPPVRGMLSETILGRHSTMEIRSVHLGGLFHAEEEIQMTSTMPNFVGQMQGLVFNGQRYLDIVKSLGPELSALPSATFKLTARFVNSPAGQPYHAATFRSKHSYVGLAMLKAYNSISIDFRFKTVEPNGLLVFNGGRRNDFVAVELVNGHIHYTFDLGDGPVTMRDKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIISL-TGNNMHLEL--AGI-------LYIGGVFKDM--YSKLPASISSRSGFEGCLASLDLGDASPSLTSDAVVPSSL--------VVSGC----EGPTKCSQNACANRGNCVQQWNAYACECDMTSYTGPTCYDESIAYEFGNNKGMVQYTFPENAQADTEEDNIALGFITTRPDAVLLRVES--ATTQDYMELEIVEGN----IFMVYNIGSVDLPLGEIGTKVNDNAYHVVRFQRKGGNATLQLDDYNVQALTPQSHHSTVFNTMSNVQVGGKF----SRNGR----NRIERPFAGVIAGLSVNKLRILDL 1363

HSP 2 Score: 133.265 bits (334), Expect = 9.977e-31
Identity = 202/893 (22.62%), Postives = 350/893 (39.19%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNS---LYKTLDTTRDLYIGGIPETLVSFLPH-SLWSGILRQGFVGCLLDISVNGDQFDLA-----------------------LKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCGR-VAPL-VKFNGFQQMIINM----PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNK---IIRSDYNCFDGNWHTLKLKRR--QLS-------VILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNG-------------INYFELAKEES-----PSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVL------QLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIR--ENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSS--QGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDC----PEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLII---EYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASP-KGKTS-----IHFNQQ-RTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFN 3297
            ++ S+ T   W     G L+  FKT + N L+ Y    T     +DF+  ++ E  L    N G G  Q       + DG  H V++   D    + +D   +   T      +    +  D+Y+GG+P    S L   +L S I    F G + ++ V  DQ   +                       L A    + G+  G + D  ++    N PC  G  CI   +  IC+C    Y G  C +  AP    F G Q +  ++         S  + ++  F T +PNG+   T       +D L + L +G +++ +    G +   I  S     D  WH + + RR  ++S       ++ ++DD+   + + +G   +LS+  + VG        R   G  +H  F G             +N  +LAK  S       N+E     GD +     P++F +  S++ LP  +      + F  +T+   G ++      Q   K+   + +E+++G++ +  + G+G +K      ++DD  WH +IL R   ++K S      D +  G+   +EL           +++LG      +  +      T++  QGF GC+    ++               AI +A    V+D     P  H     C  N C +GG C++ W R  CDC+ T + G  C +   TL FN      I+  +     T  E       +   +  ++L   +    D +   L+  + RA + +   E NL +G     +S +N  D  +H + F R  +   LQ+D      A P +G  S      H   + R++++G      +     +Q   T  +F G + GL FN
Sbjct:  110 SQNSFYTFRKWYTGLNGTLELEFKTEQPNGLVLY----TDDGGTYDFFELKLVEGALRLRYNLGGGA-QIITVGRELHDGHWHKVQVLRNDEQTSLIVDGVSQQRSTKGKEFQFGKFASNSDVYVGGMPNWYSSKLALLALPSVIFEPRFRGAIRNL-VYADQPGGSTRRQEIKQQRDIKCGDVPCDHGELPARERPLRGVRGGNTTDACER----NDPCQHGGICISTDSGPICECRNLEYDGQYCEKEKAPSEATFRGTQFLSYDLGQTGAEPIVSAQDAISFYFRTRQPNGLLFYTGH----GTDYLNLALRDGGVSLTMGLANGKQEMHIKPSKVRFDDHQWHKVTVHRRIQEISSITSFCRLVTVVDDVYTDHSHIAGKFTMLSSSRVYVGGAVN---PRALLGARVHTNFVGCLRKVEFSADTLNLNLIDLAKSGSKLIQVAGNLEYQCPSGDPQD----PVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAKVSVDGVWNDFRTPGDGTILELDG---------HMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSGK-------------AIDIAAFARVQDSASVKPSCHVQANVCNGNPCLNGGTCLEGWNRPICDCSATLYGGPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAGLLLLTSAESNSPDRLEIALVAGRVRASVRLSDREKNLLAG-----QSVLN--DNNWHTIRFSRRASNLRLQVDG-----APPVRGMLSETILGRHSTMEIRSVHLGGLFHAEE----EIQMTSTMPNFVGQMQGLVFN 943

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Zebrafish
Match: nrxn1a (neurexin 1a [Source:NCBI gene;Acc:565531])

HSP 1 Score: 375.941 bits (964), Expect = 4.469e-108
Identity = 326/1270 (25.67%), Postives = 564/1270 (44.41%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ----------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN-----------------------DKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRS-----NVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQ-KITTTPDNDIYTENTKSES-------------------STIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFI 3828
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK+    +    +   KC ++  + P++F T  S+ITL  W+  + G + F F+T E N LL +   +     Q           DF+A E+ +  L+  ++ GSG  + +  +  V+DG  ++V    +  +  + +++ +   +     + LD    LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE++   G+   CS +   +  C + PC++ G C  G+NR++CDCS T Y G +C R A ++ ++G + M I +P    +E EDV+LRF + R  G+ + T S+ S  + RLE  L+ G++ + +N G+G + I S  N  D  WHT+++ RR  S+ L++DD++  +   +G    L    +  G     ++       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ LP +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      ++DN WH V++ R+ +   +   +ID+     +   +   G  N +   +L++G   K + K   +   V S +GF+GC++S  +N            +L + AL+  G VE   E  +   +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y   P    +T  D LA G  T    +  + +    G   D++  ++     R  + + +N+G+    + E+S  + DG YH V F R+G  A+LQ+DD   I   P G      N++  I   + P+   R GR V +                       +K    F G LSGLY+N              G+K+LN +     NV VE           S ++ Q              V A  N S   P                 I      T ++ Q K TTTP +D+   + +  S                   +  Y S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I
Sbjct:  259 MATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGKS-------ADYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKLGDPKMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIFPTEVWTALLNYGYVGCVRDLFMDGQSKDIRRIAEAQRAVGVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSYDGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATTSQNSADTLRLE--LDGGRVRLTVNLGKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTEKRYMPAVPSNFIGHLQGLSFNGMSYIDLCKNGDIDYCELNAMIGYRSIVAD-PVTFKSRSSYVTLPTLQAYYSMHLFFQFKTTSPDGLILYNRGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNTPLNDNHWHNVMISRDTNNLHT--VKIDT-----KITTQTTMGAKNLDLKGDLYVGGVAKDMYK--DLPKLVHSKEGFQGCLASVDLN--------GRLPDLQSDALSTAGQVERGCEGPS--TTCQEDSCSNQGVCLQQWEGFSCDCSMTSYGGPLCNDPGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSG-LGDYLQLQIE----RGNIKVVFNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPSGNID---NERLAIARQRIPY---RLGRVVDDWLLDKGRQLTIFNSQTTIKIGGWEKGSRPFQGQLSGLYYN--------------GLKVLNMAAEGDPNVRVEGSARLVGDMPSSSITPQSS------------VSAAGNRSETSP----------------SITDITTTTASNRQGKQTTTPQDDLLVASAECPSDDEDIDPCDPSSAHPPLPEAKGYPSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYI 1433

HSP 2 Score: 127.102 bits (318), Expect = 9.057e-29
Identity = 207/890 (23.26%), Postives = 350/890 (39.33%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC-------GRVAPLV-----------KFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  ++ LL Y   E       DF    I    L    +          S T V+D   H V L     N  + +D + K     S  + +     L++GGIP  L S       S I  +  + G + ++ VNG          SE +     G + D+ +    A+  C++G  C I  +  ICDCS T + G  C       G +A L+            F G +    ++ PN  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK   P  ++V+  +    E      P++F +  S+I L K        + F  +T    G +L  +GK                 D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S  + R      GE   ++L      GGL  +    +F    E + +  N          G+ GC+   +M+ Q+K +   +  Q  +       GV   C ++   Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +        Q+   + RL  D GR  L +  NLG G    + S  N+ D  +H V   R G    L +DD         G  T + F+   T  V +     +R   +V ++     F G+L GL FN +   D+  N
Sbjct:   28 MEFTGAEGQWARFPMWNACCESEMSFNMKTKSAHGLLVYFDDE----GFCDFLELLIHNGRLSLRFSIFCAEPATVFSDTAVNDSRWHAVTLRRNFKNTTLVVDEEIKWVEVKSKRRDMTVFSHLFLGGIPPELRSVALRLTSSAIKDEVPYKGWITNLRVNG----------SEPVLIGSDGVNSDICE----ADHICLNGGVCSIVNDEPICDCSETGFQGKDCSEEEAYVGGLAHLMMGDQEREEYMATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKLGDP-KMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIF--PTEVWTALLN---------YGYVGCVRDLFMDGQSKDIRRIAEAQRAV-------GVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSY-DGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATT----SQNSADTLRLELDGGRVRLTV--NLGKG-PETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTE-----KRYMPAVPSN-----FIGHLQGLSFNGMSYIDLCKN 854

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Zebrafish
Match: nrxn1a (neurexin 1a [Source:NCBI gene;Acc:565531])

HSP 1 Score: 366.311 bits (939), Expect = 1.012e-104
Identity = 325/1279 (25.41%), Postives = 563/1279 (44.02%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ----------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN-----------------------DKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRS-----NVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQ-KITTTPDNDIYTENTKSES-------------------STIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFI 3828
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK+    +    +   KC ++  + P++F T  S+ITL  W+  + G + F F+T E N LL +   +     Q           DF+A E+ +  L+  ++ GSG  + +  +  V+DG  ++V    +  +  + +++ +   +     + LD    LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE++   G+   CS +   +  C + PC++ G C  G+NR++CDCS T Y G +C R A ++ ++G + M I +P    +E EDV+LRF + R  G+ + T S+ S  + RLE  L+ G++ + +N           +G + I S  N  D  WHT+++ RR  S+ L++DD++  +   +G    L    +  G     ++       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ LP +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      ++DN WH V++ R+ +   +   +ID+     +   +   G  N +   +L++G   K + K   +   V S +GF+GC++S  +N            +L + AL+  G VE   E  +   +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y   P    +T  D LA G  T    +  + +    G   D++  ++     R  + + +N+G+    + E+S  + DG YH V F R+G  A+LQ+DD   I   P G      N++  I   + P+   R GR V +                       +K    F G LSGLY+N              G+K+LN +     NV VE           S ++ Q              V A  N S   P                 I      T ++ Q K TTTP +D+   + +  S                   +  Y S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I
Sbjct:  259 MATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGKS-------ADYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKLGDPKMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIFPTEVWTALLNYGYVGCVRDLFMDGQSKDIRRIAEAQRAVGVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSYDGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATTSQNSADTLRLE--LDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTEKRYMPAVPSNFIGHLQGLSFNGMSYIDLCKNGDIDYCELNAMIGYRSIVAD-PVTFKSRSSYVTLPTLQAYYSMHLFFQFKTTSPDGLILYNRGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNTPLNDNHWHNVMISRDTNNLHT--VKIDT-----KITTQTTMGAKNLDLKGDLYVGGVAKDMYK--DLPKLVHSKEGFQGCLASVDLN--------GRLPDLQSDALSTAGQVERGCEGPS--TTCQEDSCSNQGVCLQQWEGFSCDCSMTSYGGPLCNDPGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSG-LGDYLQLQIE----RGNIKVVFNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPSGNID---NERLAIARQRIPY---RLGRVVDDWLLDKGRQLTIFNSQTTIKIGGWEKGSRPFQGQLSGLYYN--------------GLKVLNMAAEGDPNVRVEGSARLVGDMPSSSITPQSS------------VSAAGNRSETSP----------------SITDITTTTASNRQGKQTTTPQDDLLVASAECPSDDEDIDPCDPSSAHPPLPEAKGYPSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYI 1442

HSP 2 Score: 120.553 bits (301), Expect = 7.992e-27
Identity = 204/896 (22.77%), Postives = 348/896 (38.84%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC-------GRVAPLV-----------KFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  ++ LL Y   E       DF    I    L    +          S T V+D   H V L     N  + +D + K     S  + +     L++GGIP  L S       S I  +  + G + ++ VNG          SE +     G + D+ +    A+  C++G  C I  +  ICDCS T + G  C       G +A L+            F G +    ++ PN  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK   P  ++V+  +    E      P++F +  S+I L K        + F  +T    G +L  +GK                 D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S  + R      GE   ++L      GGL  +    +F    E + +  N          G+ GC+   +M+ Q+K +   +  Q  +       GV   C ++   Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +        Q+   + RL  D GR  L +  +        S     + S  N+ D  +H V   R G    L +DD         G  T + F+   T  V +     +R   +V ++     F G+L GL FN +   D+  N
Sbjct:   28 MEFTGAEGQWARFPMWNACCESEMSFNMKTKSAHGLLVYFDDE----GFCDFLELLIHNGRLSLRFSIFCAEPATVFSDTAVNDSRWHAVTLRRNFKNTTLVVDEEIKWVEVKSKRRDMTVFSHLFLGGIPPELRSVALRLTSSAIKDEVPYKGWITNLRVNG----------SEPVLIGSDGVNSDICE----ADHICLNGGVCSIVNDEPICDCSETGFQGKDCSEEEAYVGGLAHLMMGDQEREEYMATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKLGDP-KMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIF--PTEVWTALLN---------YGYVGCVRDLFMDGQSKDIRRIAEAQRAV-------GVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSY-DGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATT----SQNSADTLRLELDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTE-----KRYMPAVPSN-----FIGHLQGLSFNGMSYIDLCKN 863

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Zebrafish
Match: nrxn1a (neurexin 1a [Source:NCBI gene;Acc:565531])

HSP 1 Score: 366.311 bits (939), Expect = 1.142e-104
Identity = 325/1279 (25.41%), Postives = 563/1279 (44.02%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ----------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN-----------------------DKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRS-----NVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQ-KITTTPDNDIYTENTKSES-------------------STIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFI 3828
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK+    +    +   KC ++  + P++F T  S+ITL  W+  + G + F F+T E N LL +   +     Q           DF+A E+ +  L+  ++ GSG  + +  +  V+DG  ++V    +  +  + +++ +   +     + LD    LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE++   G+   CS +   +  C + PC++ G C  G+NR++CDCS T Y G +C R A ++ ++G + M I +P    +E EDV+LRF + R  G+ + T S+ S  + RLE  L+ G++ + +N           +G + I S  N  D  WHT+++ RR  S+ L++DD++  +   +G    L    +  G     ++       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ LP +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      ++DN WH V++ R+ +   +   +ID+     +   +   G  N +   +L++G   K + K   +   V S +GF+GC++S  +N            +L + AL+  G VE   E  +   +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y   P    +T  D LA G  T    +  + +    G   D++  ++     R  + + +N+G+    + E+S  + DG YH V F R+G  A+LQ+DD   I   P G      N++  I   + P+   R GR V +                       +K    F G LSGLY+N              G+K+LN +     NV VE           S ++ Q              V A  N S   P                 I      T ++ Q K TTTP +D+   + +  S                   +  Y S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I
Sbjct:  263 MATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGKS-------ADYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKLGDPKMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIFPTEVWTALLNYGYVGCVRDLFMDGQSKDIRRIAEAQRAVGVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSYDGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATTSQNSADTLRLE--LDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTEKRYMPAVPSNFIGHLQGLSFNGMSYIDLCKNGDIDYCELNAMIGYRSIVAD-PVTFKSRSSYVTLPTLQAYYSMHLFFQFKTTSPDGLILYNRGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNTPLNDNHWHNVMISRDTNNLHT--VKIDT-----KITTQTTMGAKNLDLKGDLYVGGVAKDMYK--DLPKLVHSKEGFQGCLASVDLN--------GRLPDLQSDALSTAGQVERGCEGPS--TTCQEDSCSNQGVCLQQWEGFSCDCSMTSYGGPLCNDPGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSG-LGDYLQLQIE----RGNIKVVFNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPSGNID---NERLAIARQRIPY---RLGRVVDDWLLDKGRQLTIFNSQTTIKIGGWEKGSRPFQGQLSGLYYN--------------GLKVLNMAAEGDPNVRVEGSARLVGDMPSSSITPQSS------------VSAAGNRSETSP----------------SITDITTTTASNRQGKQTTTPQDDLLVASAECPSDDEDIDPCDPSSAHPPLPEAKGYPSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYI 1446

HSP 2 Score: 118.627 bits (296), Expect = 2.782e-26
Identity = 204/900 (22.67%), Postives = 348/900 (38.67%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC-------GRVAPLV---------------KFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  ++ LL Y   E       DF    I    L    +          S T V+D   H V L     N  + +D + K     S  + +     L++GGIP  L S       S I  +  + G + ++ VNG          SE +     G + D+ +    A+  C++G  C I  +  ICDCS T + G  C       G +A L+                F G +    ++ PN  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK   P  ++V+  +    E      P++F +  S+I L K        + F  +T    G +L  +GK                 D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S  + R      GE   ++L      GGL  +    +F    E + +  N          G+ GC+   +M+ Q+K +   +  Q  +       GV   C ++   Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +        Q+   + RL  D GR  L +  +        S     + S  N+ D  +H V   R G    L +DD         G  T + F+   T  V +     +R   +V ++     F G+L GL FN +   D+  N
Sbjct:   28 MEFTGAEGQWARFPMWNACCESEMSFNMKTKSAHGLLVYFDDE----GFCDFLELLIHNGRLSLRFSIFCAEPATVFSDTAVNDSRWHAVTLRRNFKNTTLVVDEEIKWVEVKSKRRDMTVFSHLFLGGIPPELRSVALRLTSSAIKDEVPYKGWITNLRVNG----------SEPVLIGSDGVNSDICE----ADHICLNGGVCSIVNDEPICDCSETGFQGKDCSEEEAYVGGLAHLMMGDQGKRKEREEYMATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKLGDP-KMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIF--PTEVWTALLN---------YGYVGCVRDLFMDGQSKDIRRIAEAQRAV-------GVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSY-DGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATT----SQNSADTLRLELDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTE-----KRYMPAVPSN-----FIGHLQGLSFNGMSYIDLCKN 867

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Zebrafish
Match: nrxn1a (neurexin 1a [Source:NCBI gene;Acc:565531])

HSP 1 Score: 364.77 bits (935), Expect = 3.230e-104
Identity = 325/1282 (25.35%), Postives = 563/1282 (43.92%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ----------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN-----------------------DKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRS-----NVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQ-KITTTPDNDIYTENTKSES----------------------STIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFI 3828
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK+    +    +   KC ++  + P++F T  S+ITL  W+  + G + F F+T E N LL +   +     Q           DF+A E+ +  L+  ++ GSG  + +  +  V+DG  ++V    +  +  + +++ +   +     + LD    LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE++   G+   CS +   +  C + PC++ G C  G+NR++CDCS T Y G +C R A ++ ++G + M I +P    +E EDV+LRF + R  G+ + T S+ S  + RLE  L+ G++ + +N           +G + I S  N  D  WHT+++ RR  S+ L++DD++  +   +G    L    +  G     ++       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ LP +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      ++DN WH V++ R+ +   +   +ID+     +   +   G  N +   +L++G   K + K   +   V S +GF+GC++S  +N            +L + AL+  G VE   E  +   +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y   P    +T  D LA G  T    +  + +    G   D++  ++     R  + + +N+G+    + E+S  + DG YH V F R+G  A+LQ+DD   I   P G      N++  I   + P+   R GR V +                       +K    F G LSGLY+N              G+K+LN +     NV VE           S ++ Q              V A  N S   P                 I      T ++ Q K TTTP +D+   + +  S                      +  Y S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I
Sbjct:  263 MATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGKS-------ADYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKLGDPKMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIFPTEVWTALLNYGYVGCVRDLFMDGQSKDIRRIAEAQRAVGVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSYDGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATTSQNSADTLRLE--LDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTEKRYMPAVPSNFIGHLQGLSFNGMSYIDLCKNGDIDYCELNAMIGYRSIVAD-PVTFKSRSSYVTLPTLQAYYSMHLFFQFKTTSPDGLILYNRGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNTPLNDNHWHNVMISRDTNNLHT--VKIDT-----KITTQTTMGAKNLDLKGDLYVGGVAKDMYK--DLPKLVHSKEGFQGCLASVDLN--------GRLPDLQSDALSTAGQVERGCEGPS--TTCQEDSCSNQGVCLQQWEGFSCDCSMTSYGGPLCNDPGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSG-LGDYLQLQIE----RGNIKVVFNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPSGNID---NERLAIARQRIPY---RLGRVVDDWLLDKGRQLTIFNSQTTIKIGGWEKGSRPFQGQLSGLYYN--------------GLKVLNMAAEGDPNVRVEGSARLVGDMPSSSITPQSS------------VSAAGNRSETSP----------------SITDITTTTASNRQGKQTTTPQDDLLVASAECPSDDEDIDPCDPSSGGLAHPPLPEAKGYPSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYI 1449

HSP 2 Score: 118.627 bits (296), Expect = 2.906e-26
Identity = 204/900 (22.67%), Postives = 348/900 (38.67%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC-------GRVAPLV---------------KFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  ++ LL Y   E       DF    I    L    +          S T V+D   H V L     N  + +D + K     S  + +     L++GGIP  L S       S I  +  + G + ++ VNG          SE +     G + D+ +    A+  C++G  C I  +  ICDCS T + G  C       G +A L+                F G +    ++ PN  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK   P  ++V+  +    E      P++F +  S+I L K        + F  +T    G +L  +GK                 D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S  + R      GE   ++L      GGL  +    +F    E + +  N          G+ GC+   +M+ Q+K +   +  Q  +       GV   C ++   Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +        Q+   + RL  D GR  L +  +        S     + S  N+ D  +H V   R G    L +DD         G  T + F+   T  V +     +R   +V ++     F G+L GL FN +   D+  N
Sbjct:   28 MEFTGAEGQWARFPMWNACCESEMSFNMKTKSAHGLLVYFDDE----GFCDFLELLIHNGRLSLRFSIFCAEPATVFSDTAVNDSRWHAVTLRRNFKNTTLVVDEEIKWVEVKSKRRDMTVFSHLFLGGIPPELRSVALRLTSSAIKDEVPYKGWITNLRVNG----------SEPVLIGSDGVNSDICE----ADHICLNGGVCSIVNDEPICDCSETGFQGKDCSEEEAYVGGLAHLMMGDQGKRKEREEYMATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKLGDP-KMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIF--PTEVWTALLN---------YGYVGCVRDLFMDGQSKDIRRIAEAQRAV-------GVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSY-DGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATT----SQNSADTLRLELDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTE-----KRYMPAVPSN-----FIGHLQGLSFNGMSYIDLCKN 867

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Zebrafish
Match: nrxn1a (neurexin 1a [Source:NCBI gene;Acc:565531])

HSP 1 Score: 364.385 bits (934), Expect = 3.897e-104
Identity = 323/1285 (25.14%), Postives = 562/1285 (43.74%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ----------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN------QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN-----------------------DKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRS-----NVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQ-KITTTPDNDIYTENTKSES-------------------STIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFI 3828
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK+    +    +   KC ++  + P++F T  S+ITL  W+  + G + F F+T E N LL +   +     Q           DF+A E+ +  L+  ++ GSG  + +  +  V+DG  ++V    +  +  + +++ +   +     + LD    LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE++   G+   CS +   +  C + PC++ G C  G+NR++CDCS T Y G +C R A ++ ++G + M I +P    +E EDV+LRF + R  G+ + T S+ S  + RLE  L+ G++ + +N           +G + I S  N  D  WHT+++ RR  S+ L++DD++  +   +G    L    +  G     ++       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ LP +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      ++DN WH V++ R+ +   +   +ID+     +   +   G  N +   +L++G   K + K   +   V S +GF+GC++S  +N      Q+  +ST    +    +AL    +            +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y   P    +T  D LA G  T    +  + +    G   D++  ++     R  + + +N+G+    + E+S  + DG YH V F R+G  A+LQ+DD   I   P G      N++  I   + P+   R GR V +                       +K    F G LSGLY+N              G+K+LN +     NV VE           S ++ Q              V A  N S   P                 I      T ++ Q K TTTP +D+   + +  S                   +  Y S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I
Sbjct:  243 MATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGKS-------ADYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKLGDPKMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIFPTEVWTALLNYGYVGCVRDLFMDGQSKDIRRIAEAQRAVGVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSYDGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATTSQNSADTLRLE--LDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTEKRYMPAVPSNFIGHLQGLSFNGMSYIDLCKNGDIDYCELNAMIGYRSIVAD-PVTFKSRSSYVTLPTLQAYYSMHLFFQFKTTSPDGLILYNRGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNTPLNDNHWHNVMISRDTNNLHT--VKIDT-----KITTQTTMGAKNLDLKGDLYVGGVAKDMYK--DLPKLVHSKEGFQGCLASVDLNGRLPDLQSDALSTAGQVERGCEVALLKADL-------QGPSTTCQEDSCSNQGVCLQQWEGFSCDCSMTSYGGPLCNDPGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSG-LGDYLQLQIE----RGNIKVVFNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPSGNID---NERLAIARQRIPY---RLGRVVDDWLLDKGRQLTIFNSQTTIKIGGWEKGSRPFQGQLSGLYYN--------------GLKVLNMAAEGDPNVRVEGSARLVGDMPSSSITPQSS------------VSAAGNRSETSP----------------SITDITTTTASNRQGKQTTTPQDDLLVASAECPSDDEDIDPCDPSSAHPPLPEAKGYPSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYI 1435

HSP 2 Score: 126.331 bits (316), Expect = 1.373e-28
Identity = 202/880 (22.95%), Postives = 345/880 (39.20%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCG--RVAPLVKFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  ++ LL Y   E       DF    I    L    +          S T V+D   H V L     N  + +D + K     S  + +     L++GGIP  L S       S I  +  + G + ++ VNG          SE +     G + D+ +    A+  C++G  C I  +  ICDCS T + G  C   R   +  F G +    ++ PN  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK   P  ++V+  +    E      P++F +  S+I L K        + F  +T    G +L  +GK                 D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S  + R      GE   ++L      GGL  +    +F    E + +  N          G+ GC+   +M+ Q+K +   +  Q  +       GV   C ++   Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +        Q+   + RL  D GR  L +  +        S     + S  N+ D  +H V   R G    L +DD         G  T + F+   T  V +     +R   +V ++     F G+L GL FN +   D+  N
Sbjct:   28 MEFTGAEGQWARFPMWNACCESEMSFNMKTKSAHGLLVYFDDE----GFCDFLELLIHNGRLSLRFSIFCAEPATVFSDTAVNDSRWHAVTLRRNFKNTTLVVDEEIKWVEVKSKRRDMTVFSHLFLGGIPPELRSVALRLTSSAIKDEVPYKGWITNLRVNG----------SEPVLIGSDGVNSDICE----ADHICLNGGVCSIVNDEPICDCSETGFQGKDCSEEREEYMATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKLGDP-KMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIF--PTEVWTALLN---------YGYVGCVRDLFMDGQSKDIRRIAEAQRAV-------GVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSY-DGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATT----SQNSADTLRLELDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTE-----KRYMPAVPSN-----FIGHLQGLSFNGMSYIDLCKN 847

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Xenopus
Match: NRXN3 (neurexin 3 [Source:NCBI gene;Acc:100379902])

HSP 1 Score: 358.992 bits (920), Expect = 1.663e-101
Identity = 292/1049 (27.84%), Postives = 491/1049 (46.81%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFD---KCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED----HNYQ---VSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGL 3288
            VATF    Y+ Y+    P  S  D I L FKT+Q    I + G           Y+ + L    + + I    L    F+           DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   +++ R   T+ +IY D   KC ++  + PISF +  +YI+L  W   + G + F F+T E N L+ +       +K   SQ N + DF+A E+ +  L+  ++ GSG  + K ++   +DG   +V +  +  +  + ++  +     +   + LD   D+Y+GG+PE      LP  LW+ +L  G+VGC+ D+ ++G   ++   AE++N  G+ S CS  ++ K  C + PC +   C  G+NRF+CDC+ T + G TC R A ++ ++G   M I MP    +E EDV+LRF + R  G+ + T SR S  + RLE  L+ GK+ +++N G+G + + +     D  WHT+++ RR  ++ L +DD   +    G    L    I  G     +F+      F G++    FNG+ Y +L K       E+ A  G      + P++F +  SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   E  ++DN WH V++ R+NS + +   ++D+     +A  ++  G  N +    L++    + +  T  +   V S  GF+GC++S  +N            +L+  AL  +G +E   ED     N Q    +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y    +   +T  D LA G  T+V     + +    G   D++   +++ K    + + +N+GS    + E S  + DG YH V + RNG  A+LQ+D++      P G T +H          K PF   RT    Q DK   S SG   G+
Sbjct:  262 VATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGKS-------ADYVNLALKGGAVSLVIN---LGSGAFEAIVEPTNDKFNDNEWHEVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDIRLEL---SRLARIGDTKMKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVDIQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEAQNAAGVKSSCS-RLSGK-QCDSYPCKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSYDGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSADTLRLE--LDGGKVKLMVNLGKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTEKRFASAVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGMRSIIAD-PVTFRTKASYLTLSTLQAYTSMHLFFQFKTISPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSERPLNDNQWHNVVITRDNSNTHT--LKVDT-----KAVTQVINGAKNLDLKGELYIAGLVQSMYST--LPKLVASRDGFQGCLASVDLN--------GRLPDLIGDALHRSGQIERGCEDALTKANLQGPTTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNHCNDPGATYIFGKSGGLILYTWPHNDRPSTRTDRLAVGFSTTVKEGILVRIDSAPGLM-DYLQLHIVQGK----IGVTFNIGSQDISIREESAPVNDGKYHVVKYTRNGGNATLQVDNWPVNEHYPGGNTELHQKP-------KLPFKISRTPEDGQQDKGL-SISGMEDGI 1254

HSP 2 Score: 114.775 bits (286), Expect = 6.481e-25
Identity = 212/896 (23.66%), Postives = 342/896 (38.17%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILR--QGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTD-KGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAKEESPSNIEVTATIGDAEPTKEF--------------PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPI---GERAHIELKA----GGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN--ISYAGIK 3348
            W  + +  L F  +T  S  LL Y           DF    + +    L FSI+         VS   V+DG  H++ L        + LD + K        + ++   DL++GG+P  + S    +L  G +R    F G LLDI     +  L              G  G   D +GLC   PC + G C++      CDC+ T Y G  C                       R   +  F G + +  ++  N  QS  +++TL F T + NG+ + T      ++D + + L+ G +++++N G G    I+    + F+ N WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++          A IGD +  K +              PISF S  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K +D  W  V  I+ + +S + +      P    GE   ++L+     GGL  N    L L   E + +  N          G+ GCI   +++      +K++ Q  LA A    GV   C      Q    P  C +   C   W R  CDC  T   G  C++ +  L + D   Y+   +    +T  ++++   ++       +     D       + RL  D G+  L++  NLG G   L  +   + D  +H V   R G    L +DD           T + F+   T ++ +     +R   +V +     SF G+L  L FN +   D+  N  I Y  +K
Sbjct:   43 WDASTRSDLSFQLRTNVSAGLLLYFDDG----GICDFLCLSLADGHVQLRFSIDCAETAI---VSDKKVNDGGWHFLMLSRNRLRTTLVLDGEAKPGEVRPQRQHMNIVSDLFVGGVPSDIRS---GALTLGSVRDMSAFAGYLLDIKYGNTEPRLL-------------GSHGARLDLEGLCTENPCENGGACLLLDGEPTCDCTATGYVGKFCSEDVNDIPGLAHLMIDDQGRSKAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGK----SADYVNLALKGGAVSLVINLGSGAFEAIVEPTNDKFNDNEWHEVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSR---------LARIGDTK-MKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVD-IQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKNIRQ--LAEAQNAAGVKSSCSRLSGKQCDSYP--CKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSY-DGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSAD----TLRLELDGGKVKLMV--NLGKGPETLY-AGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTE-----KRFASAVPS-----SFIGHLQSLMFNGLLYIDLCKNGDIDYCELK 863

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Xenopus
Match: NRXN3 (neurexin 3 [Source:NCBI gene;Acc:100379902])

HSP 1 Score: 352.443 bits (903), Expect = 2.314e-99
Identity = 297/1087 (27.32%), Postives = 501/1087 (46.09%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFD---KCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED----HNYQ---VSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            VATF    Y+ Y+    P  S  D I L FKT+Q    I + G           Y+ + L    + + I    L    F+           DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   +++ R   T+ +IY D   KC ++  + PISF +  +YI+L  W   + G + F F+T E N L+ +       +K   SQ N + DF+A E+ +  L+  ++ GSG  + K ++   +DG   +V +  +  +  + ++  +     +   + LD   D+Y+GG+PE      LP  LW+ +L  G+VGC+ D+ ++G   ++   AE++N  G+ S CS  ++ K  C + PC +   C  G+NRF+CDC+ T + G TC R A ++ ++G   M I MP    +E EDV+LRF + R  G+ + T SR S  + RLE  L+ GK+ +++N           +G + + +     D  WHT+++ RR  ++ L +DD   +    G    L    I  G     +F+      F G++    FNG+ Y +L K       E+ A  G      + P++F +  SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   E  ++DN WH V++ R+NS + +   ++D+     +A  ++  G  N +    L++    + +  T  +   V S  GF+GC++S  +N            +L+  AL  +G +E   ED     N Q    +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y    +   +T  D LA G  T+V     + +    G   D++   +++ K    + + +N+GS    + E S  + DG YH V + RNG  A+LQ+D++      P G T +H          K PF   RT    Q DK      F++              F G LSGLY+N + + +M
Sbjct:  242 VATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGKS-------ADYVNLALKGGAVSLVIN---LGSGAFEAIVEPTNDKFNDNEWHEVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDIRLEL---SRLARIGDTKMKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVDIQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEAQNAAGVKSSCS-RLSGK-QCDSYPCKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSYDGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSADTLRLE--LDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTEKRFASAVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGMRSIIAD-PVTFRTKASYLTLSTLQAYTSMHLFFQFKTISPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSERPLNDNQWHNVVITRDNSNTHT--LKVDT-----KAVTQVINGAKNLDLKGELYIAGLVQSMYST--LPKLVASRDGFQGCLASVDLN--------GRLPDLIGDALHRSGQIERGCEDALTKANLQGPTTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNHCNDPGATYIFGKSGGLILYTWPHNDRPSTRTDRLAVGFSTTVKEGILVRIDSAPGLM-DYLQLHIVQGK----IGVTFNIGSQDISIREESAPVNDGKYHVVKYTRNGGNATLQVDNWPVNEHYPGGNTELHQKP-------KLPFKISRTPEDGQQDKGRPLTIFNTQAQIAIGGMDRGRPFQGQLSGLYYNGLKVLNM 1273

HSP 2 Score: 115.546 bits (288), Expect = 3.672e-25
Identity = 208/882 (23.58%), Postives = 340/882 (38.55%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILR--QGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTD-KGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTC--GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAKEESPSNIEVTATIGDAEPTKEF--------------PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPI---GERAHIELKA----GGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN--ISYAGIK 3348
            W  + +  L F  +T  S  LL Y           DF    + +    L FSI+         VS   V+DG  H++ L        + LD + K        + ++   DL++GG+P  + S    +L  G +R    F G LLDI     +  L              G  G   D +GLC   PC + G C++      CDC+ T Y G  C   R   +  F G + +  ++  N  QS  +++TL F T + NG+ + T      ++D + + L+ G +++++N G G    I+    + F+ N WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++          A IGD +  K +              PISF S  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K +D  W  V  I+ + +S + +      P    GE   ++L+     GGL  N    L L   E + +  N          G+ GCI   +++      +K++ Q  LA A    GV   C      Q    P  C +   C   W R  CDC  T   G  C++ +  L + D   Y+   +    +T  ++++   ++       +     D       + RL  D G+  L++  +        S     + +   + D  +H V   R G    L +DD           T + F+   T ++ +     +R   +V +     SF G+L  L FN +   D+  N  I Y  +K
Sbjct:   43 WDASTRSDLSFQLRTNVSAGLLLYFDDG----GICDFLCLSLADGHVQLRFSIDCAETAI---VSDKKVNDGGWHFLMLSRNRLRTTLVLDGEAKPGEVRPQRQHMNIVSDLFVGGVPSDIRS---GALTLGSVRDMSAFAGYLLDIKYGNTEPRLL-------------GSHGARLDLEGLCTENPCENGGACLLLDGEPTCDCTATGYVGKFCSEAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGK----SADYVNLALKGGAVSLVINLGSGAFEAIVEPTNDKFNDNEWHEVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSR---------LARIGDTK-MKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVD-IQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKNIRQ--LAEAQNAAGVKSSCSRLSGKQCDSYP--CKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSY-DGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSAD----TLRLELDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTE-----KRFASAVPS-----SFIGHLQSLMFNGLLYIDLCKNGDIDYCELK 852

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Xenopus
Match: NRXN3 (neurexin 3 [Source:NCBI gene;Acc:100379902])

HSP 1 Score: 348.977 bits (894), Expect = 3.173e-98
Identity = 291/1083 (26.87%), Postives = 495/1083 (45.71%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGG---MIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFD---KCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            VATF    Y+ Y+    P  S  D I L FKT+Q    I + G           Y+ + L    + + I    L    F+           DN WH + V+R     ++S     +   +   V +     LT T    +  T  G      +  S  +     S + N  NF GC+++++Y  ++  L++   +++ R   T+ +IY D   KC ++  + PISF +  +YI+L  W   + G + F F+T E N L+ +       +K   SQ N + DF+A E+ +  L+  ++ GSG  + K ++   +DG   +V +  +  +  + ++  +     +   + LD   D+Y+GG+PE      LP  LW+ +L  G+VGC+ D+ ++G   ++   AE++N  G+ S CS  ++ K  C + PC +   C  G+NRF+CDC+ T + G TC R A ++ ++G   M I MP    +E EDV+LRF + R  G+ + T SR S  + RLE  L+ GK+ +++N           +G + + +     D  WHT+++ RR  ++ L +DD   +    G    L    I  G     +F+      F G++    FNG+ Y +L K       E+ A  G      + P++F +  SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   E  ++DN WH V++ R+NS + +   ++D+     +A  ++  G  N +    L++    + +  T  +   V S  GF+GC++S  +N            +L+  AL  +G +E   E      +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y    +   +T  D LA G  T+V     + +    G   D++   +++ K    + + +N+GS    + E S  + DG YH V + RNG  A+LQ+D++      P G T +H          K PF   RT    Q DK      F++              F G LSGLY+N + + +M
Sbjct:  262 VATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGKS-------ADYVNLALKGGAVSLVIN---LGSGAFEAIVEPTNDKFNDNEWHEVKVTRNL--RQHSGIGHAMVNKLHCLVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN--NFMGCLKEVVYKNNDIRLEL---SRLARIGDTKMKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVDIQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEAQNAAGVKSSCS-RLSGK-QCDSYPCKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSYDGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSADTLRLE--LDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTEKRFASAVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGMRSIIAD-PVTFRTKASYLTLSTLQAYTSMHLFFQFKTISPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSERPLNDNQWHNVVITRDNSNTHT--LKVDT-----KAVTQVINGAKNLDLKGELYIAGLVQSMYST--LPKLVASRDGFQGCLASVDLN--------GRLPDLIGDALHRSGQIERGCE--GPTTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNHCNDPGATYIFGKSGGLILYTWPHNDRPSTRTDRLAVGFSTTVKEGILVRIDSAPGLM-DYLQLHIVQGK----IGVTFNIGSQDISIREESAPVNDGKYHVVKYTRNGGNATLQVDNWPVNEHYPGGNTELHQKP-------KLPFKISRTPEDGQQDKGRPLTIFNTQAQIAIGGMDRGRPFQGQLSGLYYNGLKVLNM 1291

HSP 2 Score: 109.768 bits (273), Expect = 2.611e-23
Identity = 211/909 (23.21%), Postives = 343/909 (37.73%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILR--QGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTD-KGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTC-------GRVAPLVK---------------FNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKR--RQLS-------------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAKEESPSNIEVTATIGDAEPTKEF--------------PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPI---GERAHIELKA----GGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN--ISYAGIK 3348
            W  + +  L F  +T  S  LL Y           DF    + +    L FSI+         VS   V+DG  H++ L        + LD + K        + ++   DL++GG+P  + S    +L  G +R    F G LLDI     +  L              G  G   D +GLC   PC + G C++      CDC+ T Y G  C       G V P+ K               F G + +  ++  N  QS  +++TL F T + NG+ + T      ++D + + L+ G +++++N G G    I+    + F+ N WH +K+ R  RQ S             V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++          A IGD +  K +              PISF S  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K +D  W  V  I+ + +S + +      P    GE   ++L+     GGL  N    L L   E + +  N          G+ GCI   +++      +K++ Q  LA A    GV   C      Q    P  C +   C   W R  CDC  T   G  C++ +  L + D   Y+   +    +T  ++++   ++       +     D       + RL  D G+  L++  +        S     + +   + D  +H V   R G    L +DD           T + F+   T ++ +     +R   +V +     SF G+L  L FN +   D+  N  I Y  +K
Sbjct:   43 WDASTRSDLSFQLRTNVSAGLLLYFDDG----GICDFLCLSLADGHVQLRFSIDCAETAI---VSDKKVNDGGWHFLMLSRNRLRTTLVLDGEAKPGEVRPQRQHMNIVSDLFVGGVPSDIRS---GALTLGSVRDMSAFAGYLLDIKYGNTEPRLL-------------GSHGARLDLEGLCTENPCENGGACLLLDGEPTCDCTATGYVGKFCSEAHLQNGVVGPIFKTFCTSPAAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGK----SADYVNLALKGGAVSLVINLGSGAFEAIVEPTNDKFNDNEWHEVKVTRNLRQHSGIGHAMVNKLHCLVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSR---------LARIGDTK-MKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVD-IQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKNIRQ--LAEAQNAAGVKSSCSRLSGKQCDSYP--CKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSY-DGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSAD----TLRLELDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTE-----KRFASAVPS-----SFIGHLQSLMFNGLLYIDLCKNGDIDYCELK 879

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Xenopus
Match: NRXN3 (neurexin 3 [Source:NCBI gene;Acc:100379902])

HSP 1 Score: 349.362 bits (895), Expect = 3.345e-98
Identity = 291/1058 (27.50%), Postives = 490/1058 (46.31%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFD---KCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED----HNYQ---VSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGL 3288
            VATF    Y+ Y+    P  S  D I L FKT+Q    I + G           Y+ + L    + + I    L    F+           DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   +++ R   T+ +IY D   KC ++  + PISF +  +YI+L  W   + G + F F+T E N L+ +       +K   SQ N + DF+A E+ +  L+  ++ GSG  + K ++   +DG   +V +  +  +  + ++  +     +   + LD   D+Y+GG+PE      LP  LW+ +L  G+VGC+ D+ ++G   ++   AE++N  G+ S CS  ++ K  C + PC +   C  G+NRF+CDC+ T + G TC R A ++ ++G   M I MP    +E EDV+LRF + R  G+ + T SR S  + RLE  L+ GK+ +++N           +G + + +     D  WHT+++ RR  ++ L +DD   +    G    L    I  G     +F+      F G++    FNG+ Y +L K       E+ A  G      + P++F +  SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   E  ++DN WH V++ R+NS + +   ++D+     +A  ++  G  N +    L++    + +  T  +   V S  GF+GC++S  +N            +L+  AL  +G +E   ED     N Q    +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y    +   +T  D LA G  T+V     + +    G   D++   +++ K    + + +N+GS    + E S  + DG YH V + RNG  A+LQ+D++      P G T +H          K PF   RT    Q DK   S SG   G+
Sbjct:  262 VATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGKS-------ADYVNLALKGGAVSLVIN---LGSGAFEAIVEPTNDKFNDNEWHEVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDIRLEL---SRLARIGDTKMKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVDIQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEAQNAAGVKSSCS-RLSGK-QCDSYPCKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSYDGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSADTLRLE--LDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTEKRFASAVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGMRSIIAD-PVTFRTKASYLTLSTLQAYTSMHLFFQFKTISPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSERPLNDNQWHNVVITRDNSNTHT--LKVDT-----KAVTQVINGAKNLDLKGELYIAGLVQSMYST--LPKLVASRDGFQGCLASVDLN--------GRLPDLIGDALHRSGQIERGCEDALTKANLQGPTTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNHCNDPGATYIFGKSGGLILYTWPHNDRPSTRTDRLAVGFSTTVKEGILVRIDSAPGLM-DYLQLHIVQGK----IGVTFNIGSQDISIREESAPVNDGKYHVVKYTRNGGNATLQVDNWPVNEHYPGGNTELHQKP-------KLPFKISRTPEDGQQDKGL-SISGMEDGI 1263

HSP 2 Score: 107.842 bits (268), Expect = 9.629e-23
Identity = 208/902 (23.06%), Postives = 340/902 (37.69%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILR--QGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTD-KGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAKEESPSNIEVTATIGDAEPTKEF--------------PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPI---GERAHIELKA----GGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN--ISYAGIK 3348
            W  + +  L F  +T  S  LL Y           DF    + +    L FSI+         VS   V+DG  H++ L        + LD + K        + ++   DL++GG+P  + S    +L  G +R    F G LLDI     +  L              G  G   D +GLC   PC + G C++      CDC+ T Y G  C                       R   +  F G + +  ++  N  QS  +++TL F T + NG+ + T      ++D + + L+ G +++++N G G    I+    + F+ N WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++          A IGD +  K +              PISF S  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K +D  W  V  I+ + +S + +      P    GE   ++L+     GGL  N    L L   E + +  N          G+ GCI   +++      +K++ Q  LA A    GV   C      Q    P  C +   C   W R  CDC  T   G  C++ +  L + D   Y+   +    +T  ++++   ++       +     D       + RL  D G+  L++  +        S     + +   + D  +H V   R G    L +DD           T + F+   T ++ +     +R   +V +     SF G+L  L FN +   D+  N  I Y  +K
Sbjct:   43 WDASTRSDLSFQLRTNVSAGLLLYFDDG----GICDFLCLSLADGHVQLRFSIDCAETAI---VSDKKVNDGGWHFLMLSRNRLRTTLVLDGEAKPGEVRPQRQHMNIVSDLFVGGVPSDIRS---GALTLGSVRDMSAFAGYLLDIKYGNTEPRLL-------------GSHGARLDLEGLCTENPCENGGACLLLDGEPTCDCTATGYVGKFCSEDVNDIPGLAHLMIDDQGRSKAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGK----SADYVNLALKGGAVSLVINLGSGAFEAIVEPTNDKFNDNEWHEVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSR---------LARIGDTK-MKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVD-IQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKNIRQ--LAEAQNAAGVKSSCSRLSGKQCDSYP--CKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSY-DGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSAD----TLRLELDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTE-----KRFASAVPS-----SFIGHLQSLMFNGLLYIDLCKNGDIDYCELK 872

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Xenopus
Match: NRXN3 (neurexin 3 [Source:NCBI gene;Acc:100379902])

HSP 1 Score: 348.977 bits (894), Expect = 3.376e-98
Identity = 291/1058 (27.50%), Postives = 490/1058 (46.31%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFD---KCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED----HNYQ---VSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL--SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGL 3288
            VATF    Y+ Y+    P  S  D I L FKT+Q    I + G           Y+ + L    + + I    L    F+           DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   +++ R   T+ +IY D   KC ++  + PISF +  +YI+L  W   + G + F F+T E N L+ +       +K   SQ N + DF+A E+ +  L+  ++ GSG  + K ++   +DG   +V +  +  +  + ++  +     +   + LD   D+Y+GG+PE      LP  LW+ +L  G+VGC+ D+ ++G   ++   AE++N  G+ S CS  ++ K  C + PC +   C  G+NRF+CDC+ T + G TC R A ++ ++G   M I MP    +E EDV+LRF + R  G+ + T SR S  + RLE  L+ GK+ +++N           +G + + +     D  WHT+++ RR  ++ L +DD   +    G    L    I  G     +F+      F G++    FNG+ Y +L K       E+ A  G      + P++F +  SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   E  ++DN WH V++ R+NS + +   ++D+     +A  ++  G  N +    L++    + +  T  +   V S  GF+GC++S  +N            +L+  AL  +G +E   ED     N Q    +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y    +   +T  D LA G  T+V     + +    G   D++   +++ K    + + +N+GS    + E S  + DG YH V + RNG  A+LQ+D++      P G T +H          K PF   RT    Q DK   S SG   G+
Sbjct:  242 VATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGKS-------ADYVNLALKGGAVSLVIN---LGSGAFEAIVEPTNDKFNDNEWHEVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDIRLEL---SRLARIGDTKMKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVDIQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEAQNAAGVKSSCS-RLSGK-QCDSYPCKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSYDGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSADTLRLE--LDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTEKRFASAVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGMRSIIAD-PVTFRTKASYLTLSTLQAYTSMHLFFQFKTISPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSERPLNDNQWHNVVITRDNSNTHT--LKVDT-----KAVTQVINGAKNLDLKGELYIAGLVQSMYST--LPKLVASRDGFQGCLASVDLN--------GRLPDLIGDALHRSGQIERGCEDALTKANLQGPTTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNHCNDPGATYIFGKSGGLILYTWPHNDRPSTRTDRLAVGFSTTVKEGILVRIDSAPGLM-DYLQLHIVQGK----IGVTFNIGSQDISIREESAPVNDGKYHVVKYTRNGGNATLQVDNWPVNEHYPGGNTELHQKP-------KLPFKISRTPEDGQQDKGL-SISGMEDGI 1243

HSP 2 Score: 115.546 bits (288), Expect = 4.342e-25
Identity = 208/882 (23.58%), Postives = 340/882 (38.55%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF--LHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILR--QGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTD-KGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTC--GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAKEESPSNIEVTATIGDAEPTKEF--------------PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPI---GERAHIELKA----GGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN--ISYAGIK 3348
            W  + +  L F  +T  S  LL Y           DF    + +    L FSI+         VS   V+DG  H++ L        + LD + K        + ++   DL++GG+P  + S    +L  G +R    F G LLDI     +  L              G  G   D +GLC   PC + G C++      CDC+ T Y G  C   R   +  F G + +  ++  N  QS  +++TL F T + NG+ + T      ++D + + L+ G +++++N G G    I+    + F+ N WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++          A IGD +  K +              PISF S  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K +D  W  V  I+ + +S + +      P    GE   ++L+     GGL  N    L L   E + +  N          G+ GCI   +++      +K++ Q  LA A    GV   C      Q    P  C +   C   W R  CDC  T   G  C++ +  L + D   Y+   +    +T  ++++   ++       +     D       + RL  D G+  L++  +        S     + +   + D  +H V   R G    L +DD           T + F+   T ++ +     +R   +V +     SF G+L  L FN +   D+  N  I Y  +K
Sbjct:   43 WDASTRSDLSFQLRTNVSAGLLLYFDDG----GICDFLCLSLADGHVQLRFSIDCAETAI---VSDKKVNDGGWHFLMLSRNRLRTTLVLDGEAKPGEVRPQRQHMNIVSDLFVGGVPSDIRS---GALTLGSVRDMSAFAGYLLDIKYGNTEPRLL-------------GSHGARLDLEGLCTENPCENGGACLLLDGEPTCDCTATGYVGKFCSEAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTRQRNGLILHTGK----SADYVNLALKGGAVSLVINLGSGAFEAIVEPTNDKFNDNEWHEVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSR---------LARIGDTK-MKIYGDVVFKCENVATLDPISFESPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQDRKDIRSQKNTKVDFFAVELLDGHLYLLLDMGSGTIKVKATNKKANDGEWCHVD-IQRDGRSGTISVNTKRTPFTASGESEILDLEGDMYLGGLPENR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKNIRQ--LAEAQNAAGVKSSCSRLSGKQCDSYP--CKNNAACRDGWNRFVCDCTGTGHWGRTCEREASILSY-DGGMYMKIIMPVVMHTEAEDVSLRFKSQRAYGLLVATTSRDSAD----TLRLELDGGKVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKTLKLTVDDDVAEGTMVGDHTRLEFHNIETGFMTE-----KRFASAVPS-----SFIGHLQSLMFNGLLYIDLCKNGDIDYCELK 852

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Mouse
Match: Nrxn1 (neurexin I [Source:MGI Symbol;Acc:MGI:1096391])

HSP 1 Score: 366.696 bits (940), Expect = 9.037e-105
Identity = 288/1057 (27.25%), Postives = 489/1057 (46.26%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G+    FN Q TI +G      +  G+          F G LSGLY+N + + +M
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIG-----GKEQGQ---------PFQGQLSGLYYNGLKVLNM 1280

HSP 2 Score: 129.413 bits (324), Expect = 1.909e-29
Identity = 206/899 (22.91%), Postives = 349/899 (38.82%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D A+ K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K    + K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEIQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 885

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Mouse
Match: Nrxn1 (neurexin I [Source:MGI Symbol;Acc:MGI:1096391])

HSP 1 Score: 357.066 bits (915), Expect = 1.976e-101
Identity = 292/1079 (27.06%), Postives = 494/1079 (45.78%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNM 1310

HSP 2 Score: 129.413 bits (324), Expect = 1.577e-29
Identity = 206/899 (22.91%), Postives = 349/899 (38.82%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D A+ K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K    + K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEIQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 885

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Mouse
Match: Nrxn1 (neurexin I [Source:MGI Symbol;Acc:MGI:1096391])

HSP 1 Score: 353.984 bits (907), Expect = 2.422e-100
Identity = 289/1082 (26.71%), Postives = 491/1082 (45.38%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGG---MIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R     ++S     +   +   V +     LT T    +  T  G      +  S  +     S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRNL--RQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNM 1317

HSP 2 Score: 127.487 bits (319), Expect = 7.338e-29
Identity = 206/907 (22.71%), Postives = 353/907 (38.92%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQ-------------LSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D A+ K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ              SV + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P  +++   +    E      PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K    + K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDP-KMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEIQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 892

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Mouse
Match: Nrxn1 (neurexin I [Source:MGI Symbol;Acc:MGI:1096391])

HSP 1 Score: 352.829 bits (904), Expect = 4.354e-100
Identity = 289/1079 (26.78%), Postives = 488/1079 (45.23%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNM 1302

HSP 2 Score: 134.035 bits (336), Expect = 6.043e-31
Identity = 203/891 (22.78%), Postives = 346/891 (38.83%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D A+ K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K    + K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEIQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 877

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Mouse
Match: Nrxn1 (neurexin I [Source:MGI Symbol;Acc:MGI:1096391])

HSP 1 Score: 352.829 bits (904), Expect = 4.790e-100
Identity = 289/1079 (26.78%), Postives = 488/1079 (45.23%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M
Sbjct:  279 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNM 1298

HSP 2 Score: 135.576 bits (340), Expect = 1.954e-31
Identity = 203/887 (22.89%), Postives = 346/887 (39.01%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D A+ K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                  G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K    + K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEIQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 873

[Close]

BLAST of neurexin-1 isoform X19 vs. UniProt/SwissProt
Match: sp|Q9ULB1|NRX1A_HUMAN (Neurexin-1 OS=Homo sapiens OX=9606 GN=NRXN1 PE=1 SV=1)

HSP 1 Score: 366.311 bits (939), Expect = 6.949e-104
Identity = 317/1236 (25.65%), Postives = 552/1236 (44.66%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYN-FSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQS----ILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKI-TTTPDNDIYTENTKSESSTIYK-SLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G+    FN Q TI +G      +  G+          F G LSGLY+N + + +M    + A I ++    +  E   +P+  + +S    + SE        T         +      EP+     + +D       I+       +  + I    P +      T++     Y  S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIG-----GKEQGQ---------PFQGQLSGLYYNGLKVLNMAAE-NDANIAIVGNVRLVGE---VPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPIS----QTTDD------ILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1445

HSP 2 Score: 125.561 bits (314), Expect = 1.715e-27
Identity = 205/899 (22.80%), Postives = 347/899 (38.60%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D  + K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEVQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 885

[Close]

BLAST of neurexin-1 isoform X19 vs. UniProt/SwissProt
Match: sp|A1XQX0|NR1AA_DANRE (Neurexin-1a OS=Danio rerio OX=7955 GN=nrxn1a PE=2 SV=1)

HSP 1 Score: 361.688 bits (927), Expect = 3.017e-102
Identity = 322/1285 (25.06%), Postives = 560/1285 (43.58%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGG---MIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ----------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN-----------------------DKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRS-----NVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQ-KITTTPDNDIYTENTKSES----------------------STIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFI 3828
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R     ++S     +   +   V +     LT T    +  T  G      +  S  +     S + N  NF GC+++++Y  ++  L++   AK+    +    +   KC ++  + P++F T  S+ITL  W+  + G + F F+T E N LL +   +     Q           DF+A E+ +  L+  ++ GSG  + +  +  V+DG  ++V    +  +  + +++ +   +     + LD    LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE++   G+   CS +   +  C + PC++ G C  G+NR++CDCS T Y G +C R A ++ ++G + M I +P    +E EDV+LRF + R  G+ + T S+ S  + RLE  L+ G++ + +N           +G + I S  N  D  WHT+++ RR  S+ L++DD++  +   +G    L    +  G     ++       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ LP +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      ++DN WH V++ R+ +   +   +ID+     +   +   G  N +   +L++G   K + K   +   V S +GF+GC++S  +N            +L + AL+  G VE   E  +   +C+ + C + G C+QQW    CDC+MT++ G  C+    T  F      ++Y   P    +T  D LA G  T    +  + +    G   D++  ++     R  + + +N+G+    + E+S  + DG YH V F R+G  A+LQ+DD   I   P G      N++  I   + P+   R GR V +                       +K    F G LSGLY+N              G+K+LN +     NV VE           S ++ Q              V A  N S   P                 I      T ++ Q K TTTP +D+   + +  S                      +  Y S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I
Sbjct:  263 MATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGKS-------ADYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRNL--RQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKLGDPKMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIFPTEVWTALLNYGYVGCVRDLFMDGQSKDIRRIAEAQRAVGVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSYDGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATTSQNSADTLRLE--LDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTEKRYMPAVPSNFIGHLQGLSFNGMSYIDLCKNGDIDYCELNAMIGYRSIVAD-PVTFKSRSSYVTLPTLQAYYSMHLFFQFKTTSPDGLILYNRGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNTPLNDNHWHNVMISRDTNNLHT--VKIDT-----KITTQTTMGAKNLDLKGDLYVGGVAKDMYK--DLPKLVHSKEGFQGCLASVDLN--------GRLPDLQSDALSTAGQVERGCEGPS--TTCQEDSCSNQGVCLQQWEGFSCDCSMTSYGGPLCNDPGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSG-LGDYLQLQIE----RGNIKVVFNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPSGNID---NERLAIARQRIPY---RLGRVVDDWLLDKGRQLTIFNSQTTIKIGGWEKGSRPFQGQLSGLYYN--------------GLKVLNMAAEGDPNVRVEGSARLVGDMPSSSITPQSS------------VSAAGNRSETSP----------------SITDITTTTASNRQGKQTTTPQDDLLVASAECPSDDEDIDPCDPSSGGLAHPPLPEAKGYPSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYI 1456

HSP 2 Score: 116.701 bits (291), Expect = 9.687e-25
Identity = 204/907 (22.49%), Postives = 348/907 (38.37%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC-------GRVAPLV---------------KFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQ-------------LSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  ++ LL Y   E       DF    I    L    +          S T V+D   H V L     N  + +D + K     S  + +     L++GGIP  L S       S I  +  + G + ++ VNG          SE +     G + D+ +    A+  C++G  C I  +  ICDCS T + G  C       G +A L+                F G +    ++ PN  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ              SV + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK   P  ++V+  +    E      P++F +  S+I L K        + F  +T    G +L  +GK                 D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S  + R      GE   ++L      GGL  +    +F    E + +  N          G+ GC+   +M+ Q+K +   +  Q  +       GV   C ++   Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +        Q+   + RL  D GR  L +  +        S     + S  N+ D  +H V   R G    L +DD         G  T + F+   T  V +     +R   +V ++     F G+L GL FN +   D+  N
Sbjct:   28 MEFTGAEGQWARFPMWNACCESEMSFNMKTKSAHGLLVYFDDE----GFCDFLELLIHNGRLSLRFSIFCAEPATVFSDTAVNDSRWHAVTLRRNFKNTTLVVDEEIKWVEVKSKRRDMTVFSHLFLGGIPPELRSVALRLTSSAIKDEVPYKGWITNLRVNG----------SEPVLIGSDGVNSDICE----ADHICLNGGVCSIVNDEPICDCSETGFQGKDCSEEEAYVGGLAHLMMGDQGKRKEREEYMATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKLGDP-KMKVSGVVAFKCENVATLDPVTFETPESFITLDKWSAKKAGSISFDFRTTEPNGLLLFSHGKPKPQQQKDPKSPKTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAVNKKVNDGEWYHVDFQRDGRSGTISVNSIRTPYNAPGESEILDLDDKLYLGGLPEDRAGLIF--PTEVWTALLN---------YGYVGCVRDLFMDGQSKDIRRIAEAQRAV-------GVKPSCSKEPPKQ--CLSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSY-DGSKFMKIQLPVVMHTEAEDVSLRFRSQRAYGVLMATT----SQNSADTLRLELDGGRVRLTVNLDCIRINCTTSKGPETIFSGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNVETGIVTE-----KRYMPAVPSN-----FIGHLQGLSFNGMSYIDLCKN 874

[Close]

BLAST of neurexin-1 isoform X19 vs. UniProt/SwissProt
Match: sp|Q28146|NRX1A_BOVIN (Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=1 SV=1)

HSP 1 Score: 356.681 bits (914), Expect = 1.836e-100
Identity = 316/1258 (25.12%), Postives = 556/1258 (44.20%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSG-QLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGG---MIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKI-TTTPDNDIYTENTKSESSTIYK-SLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R   + + +SG    +   +   V +     LT T    +  T  G      +  S  +     S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW  I CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M    + A I ++    +  E   +P+  + +S  +    + +    +    +   +      P      + +D       I+       +  + I    P +      T++     Y  S E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  299 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTR---NLRQTSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESQILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSRETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGISCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAE-NDANIAIVGNVRLVGE---VPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPVSQTTDD------ILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1498

HSP 2 Score: 119.013 bits (297), Expect = 1.850e-25
Identity = 205/922 (22.23%), Postives = 347/922 (37.64%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNG------DQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC--------------------------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQ-------------LSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D  + K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN       D  ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ              SV + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I               PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K    + K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C  +      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLTDTPVNDGAWHNVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSLALPVDSGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKEDNNVEGLAHLMMGDQGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQTSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESQILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEVQSTAGVKPSCSRE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 908

[Close]

BLAST of neurexin-1 isoform X19 vs. UniProt/SwissProt
Match: sp|Q9CS84|NRX1A_MOUSE (Neurexin-1 OS=Mus musculus OX=10090 GN=Nrxn1 PE=1 SV=3)

HSP 1 Score: 353.984 bits (907), Expect = 1.694e-99
Identity = 289/1082 (26.71%), Postives = 491/1082 (45.38%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGG---MIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKY-NFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFNRIPLSDM 3318
            +ATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R     ++S     +   +   V +     LT T    +  T  G      +  S  +     S + N  NF GC+++++Y  ++  L++   AK     +    +   KC ++  + PI+F T  S+I+L  W   + G + F F+T E N L+ +        + ++  Q+ + DF+A E+ +  L+  ++ GSG  + K     V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  G+VGC+ D+ ++G   D+   AE ++  G+   CS +      C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G   M I +P    +E EDV+LRF + R  GI + T SR S  + RLE+     KL + L       N  +G + + + YN  D  WHT+++ RR  S+ L +DD +      +G    L    I  G     ++       F G++   TFNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      ++DN WH V++ R+ S   +   +ID+     +   ++ AG  N +   +L++G   K   K+  +   V + +GF+GC++S  +N            +L++ AL  NG +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F+     + YK  P    +T  D LA G  T    +  + +    G   D++   + + K    + +++N+G+    + ES+  I DG YH V F R+G  A+LQ+D +  I   P G      N++  I   + P+   R GR V     DK      F+S              F G LSGLY+N + + +M
Sbjct:  283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRNL--RQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKP--CLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIAD-PVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHT--VKIDT-----KITTQITAGARNLDLKSDLYIGGVAKETYKS--LPKLVHAKEGFQGCLASVDLN--------GRLPDLISDALFCNGQIERGCEGPS--TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG-LGDYLELHIHQGK----IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNND---NERLAIARQRIPY---RLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNM 1317

HSP 2 Score: 127.487 bits (319), Expect = 5.133e-28
Identity = 206/907 (22.71%), Postives = 353/907 (38.92%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEI-RESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQF------DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQ-------------LSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHI----ELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLI-------IEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F  KT  +  L+ Y   E       DF    + R   L  S +         ++ TPV+DG  H V++  +  N  + +D A+ K     S  + +     L++GG+P  L  + L  +L S   R+ F G + D+ VN  Q       ++ L  E  N  G     +G+  + G+C N     G C +  ++ +CDCSRT + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ              SV + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P  +++   +    E      PI+F +  S+I LPK +      + F  +T    G +L  +GK               D+  +E++ G+L LL + G+G  K    + K++D  W+ V   R+      S    R      GE   +    EL  GGL  N    +F    E + +  N          G+ GCI   +++      +K + Q  +A   +  GV   C ++      C  N C + G C   W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       +     D       + RL  D GR  L        I  N   G   L  +  N+ D  +H V   R G    L +DD   +     G  T + F+   T  + +     +R   SV ++     F G+L  L FN +   D+  N
Sbjct:   36 AEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDE----GFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPNSGGGSPCEAGEEGEGGVCLN----GGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDP-KMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF--PTEVWTALLN---------YGYVGCIRDLFIDG----QSKDIRQ--MAEIQSTAGVKPSCSKE--TAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATVLSY-DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSAD----TLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF-AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIITE-----RRYLSSVPSN-----FIGHLQSLTFNGMAYIDLCKN 892

[Close]

BLAST of neurexin-1 isoform X19 vs. UniProt/SwissProt
Match: sp|A1XQY1|NR3BA_DANRE (Neurexin-3b OS=Danio rerio OX=7955 GN=nrxn3b PE=2 SV=1)

HSP 1 Score: 353.984 bits (907), Expect = 3.590e-99
Identity = 287/1087 (26.40%), Postives = 501/1087 (46.09%), Query Frame = 1

Query:  193 IIHTGTTEEIPVATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGG---MIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY--------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRID----SQPIGERAHIELKA----GGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTK--NTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIH-FNQQRTIYVGKYPFP---------------NQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            ++ +    E  VATF    Y  Y+    P  S  D I L FKT Q    I + G           Y+ + L D  + + I    L    F+     +     DN WH I V+R     ++S     +   +   V +     LT T    +  T  G      +  S  +     S + N  NF GC+++++Y  ++  L++   A+I    +  +G+I F KC ++  + PISF T  S++ L  W   + G + F F+T E N L+ +        + S + + N+ DF+A E+ +  L+  ++ GSG  + K +   V+DG+ H+V +  +  +  + +++ +     +   + LD   +LY+GG+P+      LP  LW+ +L  G+VGC+ D+ ++G   D+   AE++N+ GI S CS  VT K   +N    +G C  G+NRFICDC+ T Y   TC R A ++ ++G   M + MP    +E EDV+LRF++ R  G+ +   SR S  + RLE  L++G++ +++N G+G + + +     D +WH++++ RR  ++ L++DD   +   +G    L    +  G     +F+      F G++    FNG+ Y ++ K       E+ A  G      + P++F +  SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   +  ++DN WH V++ R+   S++   ++D    SQ +    +++LK      GL  N ++NL                  V   +GF+GC++S  +N            +L+  AL  +G +E   E  +   +C+ + C + G CIQQW    CDC+MT++ G +C+    T  F      ++Y     +  +T  D LA G  T++     + +     +  D+I   + + K    + + +N+G+    + E +  + DG YH V F RNG  A+LQ+D++      P G + I  F         KY  P               N +   S+  +     + G LSGLY+N + + +M
Sbjct:  243 MVKSPQAREENVATFRGSEYFCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKS-------ADYVNLALKDGAVSLVIN---LGSGAFEAIVEPVNGKFNDNAWHDIKVTRNL--RQHSGIGHAMVNKLHCLVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN--NFMGCLKEVVYKNNDIRLELSRLARIADPKMKLQGDIVF-KCENVPTLDPISFETAESFLGLPKWNTKRVGSISFDFRTSEPNGLILFTQGKPQDKKDSRSQRSNKVDFFAVELLDGHLYLLLDMGSGTIKVKATQNKVNDGVWHHVDIQRDGRSGIISVNSRRTPFTASGENEILDLEGNLYLGGLPDNRADLILPTELWTAMLNYGYVGCIRDLFIDGRSKDIRQIAEAQNVGGIKSSCS-KVTAKQCDSNSCKNNGICKEGWNRFICDCTGTGYWDRTCEREASILSYDGSMYMKVVMPTIIHTEAEDVSLRFMSQRAFGLLMAATSRESADTLRLE--LDSGRVKLIVNLGKGPETLYAGQKVNDNDWHSVRVTRRGKNIKLMVDDDVAEGQMNGDHTRLEFSNVETGILTERRFASTAPSNFIGHLQGLKFNGLLYIDMCKNGDIEFCELNARFGMRSIVAD-PVTFKTKGSYLGLATLQAYSTMHLFFQFKTTSGDGFILFNSGDGNDFIAVELVKGYIHYVFNLGNGPSLLKGNSDSPLNDNQWHNVVITRD--ASNTHTLKVDAKSVSQVVNGAKNLDLKGDLFVAGLGPNMYQNL---------------PKLVVPREGFQGCLASMDLN--------GRLPDLINDALFRSGQIERGCEGPS--TTCQEDSCANMGVCIQQWENFTCDCSMTSYSGTQCNDPGATYIFGKGGGLIMYTWPNNERPSTRTDRLAVGFSTTIKDGILVRIDSAP-RLGDYIMLHIEEGK----VCVTFNIGTVDISVKEMTTEVNDGKYHVVRFTRNGGNATLQVDNWPINEHFPSGNSDIERFQMANKKIPFKYTRPVEDWLHEKDRQLTIFNTQATISIGGNDRKRPYQGQLSGLYYNGLKVLNM 1278

HSP 2 Score: 126.331 bits (316), Expect = 1.259e-27
Identity = 208/902 (23.06%), Postives = 351/902 (38.91%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETL-VSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIIN---------------------MPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKR--RQLS-------------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIGDAE--PTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRE--------NSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANN--GVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDS-----FSGYLSGLYFNRIPLSDMIDN 3327
            + FT +E  +     W  + +  L F FKT  S+AL+ Y   +      F   + E  +  L FS++          S   V+D   H+  +   +    + LD D K++      + +    DLY+GG+P+ +  S L  +L +      F G + D+   G++    L ++   +             +G C   PC + G C +      CDCS+T YTG  C     + K  GF  M+ +                       N  QS  +++TL F T + NG+ + T      ++D + + L++G +++++N G G    I+      F+ N WH +K+ R  RQ S             V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LA+   P        +   E  PT + PISF +  S++ LPK +      + F  +T    G +L   GK               D+  +E++ G+L LL + G+G  K    + K++D +WH V + R+        NS+ + F    +++ +    ++ L  GGL  N  + +     E + +  N          G+ GCI   +++      +K + Q    IA A N  G+   C +    Q  C  N C + G C + W R  CDC  T +    C++ +  L + D   Y+   +    +T  ++++    +       +     +       + RL  D GR  LI+  NLG G   L  +   + D  +H V   R G    L +DD                N   T    +  F N  TG  +  ++ F S     F G+L GL FN +   DM  N
Sbjct:   24 LEFTGSEGQWARYLRWDASTRSDLSFQFKTAISDALVLY--FDDGGYCDFLLLSIEDAKLKLRFSVDCAETTI---TSDKMVNDSHWHFATISRHNLRTVLALDGDSKVDEVRPQRQFMKIVSDLYLGGVPQDIRTSAL--TLPAAKEMPPFKGIITDLGY-GNKVPTRLGSQKVRLEM-----------EGFCTENPCENGGSCSMADGEAYCDCSKTGYTGRYCNEA--VNKTPGFAHMVKSPQAREENVATFRGSEYFCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGK----SADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDIKVTRNLRQHSGIGHAMVNKLHCLVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADPKMKLQGDIVFKCENVPTLD-PISFETAESFLGLPKWNTKRVGSISFDFRTSEPNGLILFTQGKPQDKKDSRSQRSNKVDFFAVELLDGHLYLLLDMGSGTIKVKATQNKVNDGVWHHVDIQRDGRSGIISVNSRRTPFTASGENEILDLEGNLYL--GGLPDNRADLIL--PTELWTAMLN---------YGYVGCIRDLFIDG----RSKDIRQ----IAEAQNVGGIKSSCSKVTAKQ--CDSNSCKNNGICKEGWNRFICDCTGTGYWDRTCEREASILSY-DGSMYMKVVMPTIIHTEAEDVSLRFMSQRAFGLLMAATSRESAD----TLRLELDSGRVKLIV--NLGKGPETLY-AGQKVNDNDWHSVRVTRRGKNIKLMVDD---------DVAEGQMNGDHT----RLEFSNVETG--ILTERRFASTAPSNFIGHLQGLKFNGLLYIDMCKN 853

[Close]

BLAST of neurexin-1 isoform X19 vs. TrEMBL
Match: A0A210PI37 (Neurexin-1a OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT10079 PE=4 SV=1)

HSP 1 Score: 400.208 bits (1027), Expect = 5.447e-114
Identity = 319/1062 (30.04%), Postives = 503/1062 (47.36%), Query Frame = 1

Query:  250 YIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMI-PMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFL-TRGEIYFDKCSDLFIIKPISFTTEASYITLAGW-AWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGN-WHTLKLKRRQLSVILIIDD----------------------MEKKYNFSGSSKLLSNDIIAVGKYETD--KFSRY--FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEI-KIDDNIWHRVILIRENSKSSSFAFRIDSQ-PIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGV--VEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN-DYPAYLIYKLSPTK--NTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            Y + +   PT S+ D ++L F+T+Q    +FY G        G  ++++ L +  + + +    L   T+            DN WH + V RK       +G   I ++VDG            T L S+ +  GG   P T     +Q         TNFKGCM+K+IY +D+  LD+   A  +   L   G++ F+KC D+   +P++FTT  SYI L  W   +  G L F+F T E N ++ Y     +     DF+AFEI++ F++  I+ GSG  + +VS  PVSD   H V L        +  D  +           LD    LY+GG+ +    + LP  +W+G+L  GFVGC+ D+ +NG++ DL   A  ++ T IV+ C      +  C  RPC++ G+C  G+NR++CDC  T Y GD C   A  + F+  Q M I +     +E ED++LRF T  PNG+  +T S  S   D + ++LENG + + +  G G+KI+       D + WHT+ +KRR   V L +D+                      +    +   +++ L+   + VG+   D  +  +Y  F G M  F FNG ++FE+AK +   NIE TA     EP    P++F S  +Y +L K+  Y +F + F  KT    G ++   G+  D+L  E+  GYL+ ++N G G  + V   I ++ DN WH V L+R      +   R+D Q P  E  H    +  L+FN    L++G   K +   N +   ++S  GF+GC++S  +N  +        +   +IA    G+  + D P ++ +Q +C      + GRC+QQW    CDC MT++ G  C   S +  F    P  LIY    +K  NT  D++A G +T    +  + +        D+I  +L+       + + YN+G+    L +      +G YH + F R+G  A+LQI++   +  +P G+    FN+Q  IY+G Y      TG   Q       F G L GL FN I + +M
Sbjct:  262 YEWPAKGAPT-SNTDEVSLYFRTRQPSGLLFYTGQ-------GSDFLIVSLKNGGVSVTVN---LGSGTYDSEIRPHAYRFDDNHWHHVHVKRKTRELTRQNGYTGIDIMVDGGFKKSGTTAGDFTMLSSRLLYVGGSPNPSTLYGARVQ---------TNFKGCMKKVIYKSDSVTLDLTTLAIEQSDILKVVGDVVFNKCHDIVESQPVTFTTPESYIILPSWEVGSAGGSLSFAFMTNEPNGVVMYNSGTQNS----DFFAFEIQDRFMYLIIDLGSGAMRIQVSMQPVSDAKLHEVSLEHIGRRGWILFDGQRVNYTVRGENSNLDMVGVLYVGGVNDYKEKYQLPKEMWAGMLGYGFVGCMQDVVINGNKMDLLNAARKQSKTDIVNFCR---PSEPQCMTRPCINNGQCSEGWNRYVCDCKATRYVGDFCQTEAATLAFDSAQFMKITLDKESHTEAEDISLRFRTQHPNGLLFMTSSYRS--FDSMALYLENGLVKLEIRVGSGSKILTIGRRRLDDDQWHTVIIKRRGSQVELSLDNDNPIGDYIPVSYTMVLYVKNLVLGYADSLPRNARELNLRRMEVGRMVQDDNRLRQYSGFVGSMQQFIFNGHHFFEMAKSQDIQNIETTARFLTDEPMLMNPVTFKSKEAYAQLEKLSAYLEFSVYFKFKTTEPDGLIMYNGGRGQDFLAFELQGGYLHYVYNTGAGAKRVVVNTINRLSDNEWHDVRLLRPVMDKQT--IRVDDQHPTVENMH---GSDTLHFNLEGMLYVGGVSKTM--YNSLPKLISSRHGFQGCLASLDLNGPRPDILNDSIKVFSSIARGCQGLKALIDRPSNNCHQYACL-----NEGRCVQQWNSYTCDCDMTSYTGPMCTDASVSYTFGLGTPGILIYNYPESKRTNTKYDQMALGFRTMQRNALLVRVES--ITNEDYIEVQLVDGN----VFVVYNMGTDNHPLGQLLRKHNNGNYHVIRFTRSGANATLQINEGPIVHKNPTGEQLSVFNEQARIYIGGY---KNSTGIHRQ-------FVGTLQGLVFNGISVLEM 1266

HSP 2 Score: 115.931 bits (289), Expect = 4.891e-22
Identity = 184/853 (21.57%), Postives = 329/853 (38.57%), Query Frame = 1

Query:  895 SYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDAD---KKIEHTNSLYKTLDTTRDLYIGGIP---ETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTCG--RVAPLVKFNGFQQMIINMP--NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG---NKIIRSDYNCFDGNWHTLKLKRRQLSV----------ILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETD------KFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIGDA------EPTKEFPISFPSVNSYIRLPKIDM-YGDFKLEFLIKTRNNKGSVLQLYG-KSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTS--SQGFEGCISSFYMNQTKYVSTKSVYQNLLAIAL--ANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIAS-PKGKTSIHFNQQRTI-YVGKYP-------FPNQRTGRSVQNDKTFDSFSGYLSGL 3288
            S+     W   Q G +   FKT + + L+ Y           D++  ++    LH     GS   +  V    ++D   H + +     N+ + +D+    +    T+  +    T   +++GGI    E   S L  +L +  L   F G + +I +  +     ++ E  +  GIVS       +     + PC  G  C+       C+CS T++ G+ C   R    V F G Q  +   P      S  ++V+L F T +P+G+   T       SD L + L+NG +++ +N G G   ++I    Y   D +WH + +KR+   +          I++    +K    +G   +LS+ ++ VG           +    F G M    +      ++   LA E+S    ++   +GD       +  +  P++F +  SYI LP  ++      L F   T    G V+   G ++ D+   EI   ++ L+ + G+G  +       + D   H V L     +     F       G+R +  ++    N +    L++G    Y  K    ++        GF GC+    +N  K         +LL  A   +   +V  C      +  C    C + G+C + W R  CDC  T ++G+ C   + TL F D   ++   L    +T  ++++   +T        +          F S  L  + G  L+ +E  +GSG   L      + D  +H V  +R G+   L +D+ N I    P   T + + +   + Y    P             GR VQ+D     +SG++  +
Sbjct:   35 SFAKYQKWNPCQNGSIHLEFKTKDMSVLILYMDDG----GHSDYFELKLLTGSLHLRFTLGSAPMRINVGQR-LNDNRWHKISIKRNRKNITLVVDSQSYTRTYHSTDQDFGYYATNSPVFVGGISNEYEDKTSSL--TLPAIYLEPRFTGSIRNI-LYSNCGGPPMRPELLDYRGIVS------ENDQCVVSDPCQHGGICVTHDEGVACNCSYTDFEGEFCSQKRAPSEVTFFGSQYFMYEWPAKGAPTSNTDEVSLYFRTRQPSGLLFYTGQ----GSDFLIVSLKNGGVSVTVNLGSGTYDSEIRPHAYRFDDNHWHHVHVKRKTRELTRQNGYTGIDIMVDGGFKKSGTTAGDFTMLSSRLLYVGGSPNPSTLYGARVQTNFKGCMKKVIYKSDSVTLDLTTLAIEQS----DILKVVGDVVFNKCHDIVESQPVTFTTPESYIILPSWEVGSAGGSLSFAFMTNEPNGVVMYNSGTQNSDFFAFEIQDRFMYLIIDLGSGAMRIQVSMQPVSDAKLHEVSL-EHIGRRGWILFD------GQRVNYTVRGENSNLDMVGVLYVGGVNDYKEKYQLPKEMWAGMLGYGFVGCMQDVVINGNK--------MDLLNAARKQSKTDIVNFCRPS---EPQCMTRPCINNGQCSEGWNRYVCDCKATRYVGDFCQTEAATLAF-DSAQFMKITLDKESHTEAEDISLRFRTQHPNGLLFMTSS----YRSFDSMALYLENG--LVKLEIRVGSGSKILTIGRRRLDDDQWHTVIIKRRGSQVELSLDNDNPIGDYIPVSYTMVLYVKNLVLGYADSLPRNARELNLRRMEVGRMVQDDNRLRQYSGFVGSM 840

[Close]

BLAST of neurexin-1 isoform X19 vs. TrEMBL
Match: A0A4E0S3K8 (Neurexin OS=Fasciola hepatica OX=6192 GN=D915_000090 PE=4 SV=1)

HSP 1 Score: 399.053 bits (1024), Expect = 2.401e-112
Identity = 337/1237 (27.24%), Postives = 558/1237 (45.11%), Query Frame = 1

Query:  286 DMDAINLEFKTKQDFSHIFY---VGTQPSHSKTGLQ--YILMYLDDRQLGIRIK--------HDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDS-DFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSD----------LFIIKP-------ISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETS---------QLNQ----------FDFYAFEIRESFLHFSINTGSG--------VYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHT--NSLYKTLDTTRDLYIGGIPETL---VSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDG-RCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGK-------YETDKFS-------------RYFTGYMMHFTFNGINYFELAKEESPSN--------IEVTATIGDAEPTK--EFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQL-YGKSGDYLILEIVHG-YXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYM----------------NQTKY--VSTKSVYQNLLAIALANNGVVEDCPE-----DHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN-DYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQID-DYNRIIASPKGKTSIHFNQQRTIYVGKYPF---PNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXX--------------IVVAKSNCSNIEPLHNLD-CKVSDSAGIIRPIVSYK 3573
            + D I  +F+++  F  I Y   + + P  S T +   ++++YL +  +   ++        H ++     ++ C+S Y TCTD +WH +  S  K S   S         VD +  +  ++  T      Q++  G    ++DS DF     +S       F GC++++ +  D   + +L+  K     +        D+CS           L    P       ISF     Y+ + GW     G++ F F+T E N LL Y  S             LN           FD +A E+R   L   +NTGSG        V +   S T ++D   H VK+ F  G++ V++D    + HT    +YK L+     YIGG+PE +    SF+   +WS  LR  ++GCL D  V+G  +DL L+  +      V         +G+C    C +G  C  G+NRFICDC  +N+ G+ C     + +FNG Q + I   P   QS  ED+ +RF T   NG+ + T+S     SD LE+ +E G + +  +FG  +K  R      D +WHT+++ RR+  + L +D   + Y+     + LS+  I +G+          D F                F G +M F FNG++  ++AK              +E+TA+     P K  EFP+S  + +SYI +     + + +LEF +K   N G +L + YG S D ++LE+V+G    + +   N  N + ++   I D+ WH + ++R     +  +  +D + I     I+L     + +    + LG   +   +  Q +    S  GF GC++S  +                NQT    V   +++ +     +  N V   C +      H+   +C P +C  GG C+QQW   RCDC++T+  G  C +VS  + F+ +  + L ++++PT+NTT D+LAFGIQ     S  + LI+G G   D++   ++K + R +L++ YN+G+G   L E +V+I DG YH V F R+G    L++D +Y R    PK K   HFN ++ I +G  PF   P   T  S     T   F G++SG YFN + L  ++  +   GI L    N+ VE +F P  +  + + +    +      K+                +++AK +C +   +++   C   D +GII+P V ++
Sbjct:   71 EADEIAFQFRSR-GFDQILYSSVLASSPDMSDTLIMQIHLVIYLTNGSVHFMVENYSKNNFPHMQVVGQRRRIDCLSDYETCTDAQWHQVRQSVLKNSLAIS---------VDNQPPLTYLLSYTTNRWSIQAVYLGHRPDISDSKDFG----SSLSVPRQQFHGCIRRLFFKIDGKKIPVLSLEKQDLIVVQLESSQILDECSRNTLSPSHAHRLPYTWPYRSAPEYISFVRPGGYVRIPGWHVVLSGEITFRFRTNEINGLLIYGSSVHQYEVIDYADLGLNAIPIPGGGKAGFDIFAMELRNGHLFCVLNTGSGSLQLGRTGVNRHMQSVTFLADSKEHKVKIQFNQGSIAVEVDGRHYMAHTADEKMYKYLNLNGVFYIGGVPEPIRRVSSFISPEVWSTRLRWDYIGCLSDFRVDGRLWDLELELRACWARSYVEPLCRIQNVEGVCTRNSCANGGLCENGWNRFICDCHDSNFIGEKCSEAPVVAEFNGHQWISITFSPFPVQSAVEDLIIRFQTKHKNGLLLTTRSPSMAESDCLELRVEAGYIKLTYDFGEESKQYRGLTYVSDNSWHTVRVHRRERHLNLTVDHAAQVYDIPKYGRFLSHKQIILGRNTKISEPKSLDAFPDRPMILSPERTKLTVFIGNIMAFWFNGLDILKMAKHLLAQTAYTVWRERLEITASESSPRPGKMLEFPLSLETHDSYIEMKLDGSFNELQLEFWLKADKNFGILLLMDYGVS-DIIVLELVNGDLNIVCWQRNNTKNVQSKRNGAIIDSKWHWIKVVRNWGSYNLLSVHVDQEII----KIDLPPSETSRSQL--ILLGGVPRDADQVEQYKQHFHSMYGFAGCVASIQIKQFNQSITALGNAELSNQTNAGDVRVTTLFSDQYGSKIRWNNVEPGCRQKPNGLQHSLNGNCTPRVCQFGGSCVQQWGATRCDCSLTSLTGTHCTEVSSAIHFSVNQNSVLSFEMNPTQNTTRDQLAFGIQVVQPGSVVLFLIQGQGDSPDYLEVSIVKVEARYVLLVRYNMGAGQHTLYEPNVDITDGQYHIVQFIRDGPNGLLRVDLEYER-SNLPKDKHGSHFNGEKLIRLG-VPFKSSPVFATNASRTMGAT--EFEGFISGAYFNDVNLLSVLQGLVIPGIFLSESQNIRVEKQFQPKMEHLKHVRTRNDHQVAANDMKHQTNDASFGNHEVHSGPLIIAKRDCVDPGGMYDTKTCSPYDRSGIIQPHVDFR 1282

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BLAST of neurexin-1 isoform X19 vs. TrEMBL
Match: A0A430QHY5 (Neurexin OS=Schistosoma bovis OX=6184 GN=DC041_0012455 PE=4 SV=1)

HSP 1 Score: 398.667 bits (1023), Expect = 4.979e-112
Identity = 348/1270 (27.40%), Postives = 576/1270 (45.35%), Query Frame = 1

Query:  292 DAINLEFKTKQDFSHIF---YVGTQPSHSKTGLQ-YILMYLDDRQLGIRI------KHDRL--PESTFKVTCVSIYSTCTDNRWHTISVSRKKTS---EKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIK---------------RYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKS---------------------ETSQLNQFDFYAFEIRESFLHFSINTGSGVYQ--------QKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSL--YKTLDTTRDLYIGGIPETLV---SFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYE-------TDKFSRY--------------FTGYMMHFTFNGINYFELAK--EESPS------NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKK-VRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED------HNYQVSCR-------------PNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPA-YLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDS---FSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNF------------------QSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNL-DCKVSDSAGIIRPIVSYKINTVTHSQKIT---TTPDNDIYTENTKSESSTIYKSLE 3678
            + I  EF+T+++   +F          H+K  +  Y+L YL +  L + +      K   L  P +   ++C+S Y TC D +WH I ++ KK       +S  Q+ +       ++  R++ L  T L +   TF   IP              + NLTNF+GC Q IIY +    + +L     K                Y L +  I  D      +   +SFT   SY+ + GW     G++ F  +T   N L+ Y  S                     E  Q   +D +A E+R   LHF +NTGSG+ Q        +  S   +SDG  H +++ F++G++ + +D +  + H   +  YK L+     YIGG+PE++    SF+   +WS  LRQ FVGCL +  VN   +D+ L+         V       +    C ++PC + G+CI  +N + CDCS TN++G TC     +V F+GFQ + I   P   QS  E++TLRF T   +G  + T+S +  A D LE+ + +G L+++ N G  + I  +     D  WHT+K+ RRQ  +   +D++ + ++     + LS+  + +G  E        D  +++              F GY+M F FNG+++   A+  +  PS       +++TAT  + EP  E P++F + +S I +       +F L   IK +   G+VL L       LILE + G L L+    +   K  + +  ++    W+ + +I++ S +     R+++Q    + +I       N+ + + + +GS     S  +   + +  + GF+GC++SF  N +      S+   L     +   V      D      HN Q+ C               N C   G C+QQW  I CDC++T F G+ CDK   +++ +++P  Y +++L+  +NTTLD+LAFGIQ     + SII I+G G+  DFI   ++ +K +  L + +N+G G   L + +VN  DG +H V F R    + L +D  + I    + + + HFN  + IY G+ P    +   SV N+  F S   F G+++GL  N I L D++      GI L  R N+ +   F PN                   ++    L+     +     K  PIVV K+ C   +  +N  +C+ +D  GII+P++++  N +T    I    T P     TE  K +SS  YK  +
Sbjct:   32 EKIFFEFRTRKENQIMFSFELTSILTQHTKMKVDSYLLGYLLNGALVVNLFNHFSEKRSYLNHPNTQKIISCISDYDTCADTQWHQILLTIKKNDILLVLDSQPQVKLNPFGHDGLITIRVMHLGGTFLNNSKETFTRFIPS-------------IGNLTNFRGCFQSIIYKSGELFIPLLITKNTKYIQSQLPIQSNLRNCDYKLLQRNINIDHSK---VNSYVSFTKPGSYLRITGWKVVLHGEITFILRTTTLNGLIIYSNSINEYELFPKNINEPNLLENIHEVKQTG-YDIFALELRLGRLHFLLNTGSGIVQPEFDRKYFESESKGFISDGKEHSIQIVFDEGDLIINVDGENFVTHGTGIKTYKYLNLNEYFYIGGLPESVRQINSFISPEVWSAQLRQDFVGCLGEFIVNKRLWDIDLERRPCWSKPFVENGCKLSSSIDFCTDKPCRNKGQCISSWNIYECDCSNTNFSGKTCTENPIIVSFDGFQWLWIKFSPLPIQSSVEELTLRFRTKYEDGFLLTTRSSILSAPDCLELKITSGYLSLIYNLGAIDNIYHNPVYIADDQWHTVKIYRRQNVLNFSVDNLFQTFDIPKDGRYLSHRHLILGNSEDSLTNQLIDTPTQFNHNIKQINNLNVHVFIGYIMVFLFNGVDFLRTAQNLKHDPSLYIWKDKLDITATQSNYEPNHELPLTFSNKDSTIEIELEHSTSEFILGMWIKWKK-YGTVLSLQDGFRQNLILESIDGRLQLIHMNKDQAEKYFIGENQRVVVREWYHIEVIKQES-TKLIHIRVNNQSTIVKMNIS------NYFALKTINIGSLSTRNSNYDTYSNYMQRTTGFQGCVASFSFNYSIDYDQSSLNIKLNNTTPSRYHVNYLYSNDTQKVSLHNIQMGCHFSDSKHLDLNQCSENPCRFNGICMQQWNSITCDCSLTGFTGKFCDKAGTSVRLSEFPRRYAVFELNSPQNTTLDKLAFGIQIINPGTMSIIHIQGQGQSPDFIQLSVLHNKDQLNLHVRFNMGGGTQTLFQPNVNFNDGHFHIVQFIRQEAKSILLVDFQHEITKLTEDQNNKHFNLLKRIYFGEAP--KMKEKLSVNNNSEFTSRKGFEGFITGLNLNNINLIDLLYGNMVPGIYLKTRENIELNPNFKPNMKKLHAHNKRTEPETRSQNEANDMQLTATDFHDRINDYKTQPIVVPKTECLKYDSSYNYKECQPADLDGIIQPLITFSDNPLTMRAIINDYKTQPIVVPKTECLKYDSSYNYKECQ 1274

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BLAST of neurexin-1 isoform X19 vs. TrEMBL
Match: A0A4Z2DG09 (Neurexin-1 (Fragment) OS=Schistosoma japonicum OX=6182 GN=EWB00_001292 PE=4 SV=1)

HSP 1 Score: 394.43 bits (1012), Expect = 1.617e-111
Identity = 309/1096 (28.19%), Postives = 515/1096 (46.99%), Query Frame = 1

Query:  688 SIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFD---KCSDLFIIKP------------ISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETS------QLNQ--------------FDFYAFEIRESFLHFSINTGSGVYQ--------QKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSL--YKTLDTTRDLYIGGIPETLV---SFLPHSLWSGILRQGFVGCLLDISVNGDQFDLAL-KAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYE---TDKF-----------------SRYFTGYMMHFTFNGINYFELAK--EESPS------NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKK-VRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQT----------KYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCR-------------PNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYP-AYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLM--KDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDK----TFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQS----KQSI--------------LSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNL-DCKVSDSAGIIRPIVSYKINTVT 3588
            S +ET +   N TNF+GC + +IY      + +L     K     R E+      +  D  +++P            +SFT   +Y+ + GW     G++ F+ +T   N L+ Y  S +       ++N+              FD +A E+R   LHF +NTGSG+ Q        +  S   +SDG  H +++ F++G++ + +D +  + H   +  YK L+     YIGG+PE++    SF+   +WS  LRQ FVGCL +  VN   +D+ L +    +   + SGC   ++   LC ++PC + G+C   +N F CDCS TN++G TC     +V  NGFQ + +   P   QS  E++TLRF T   NG  + T+S +  A D LE+ + +G L ++ N G  + +  +     +  WHT+K+ RRQ  +   +D++ + ++     + LS+  +  G  E   TD+                     F GY+M F FNG+++   A+  +  PS       +++TAT  D EP  E P++F   +S I L       +F LE  IK +   G++L L    G   ILE+  G L  +        K  +    K+ +  W+ + +I++     S   +++ Q         +K     + + + + +GS  K  S      + +  + GF+GC++SF +N +          ++ + KS+ +  L    +N     D    HN Q+ C               N CH  G C QQW  + CDC++T F G+ CD    ++  ++ P  Y I++L+  +NTTLD LAFGIQ     S S++ I+G G+ SD+I   ++  K K +  L++ YN+G G   L + +VN  DG +H V F R+ +   L ID  + I    + + + HFN  + IY G+   P +   + +QN+     T + F G+++GL FN I L D+++     GI L  R N+ +   F PN +     K+ I              L+     + +   K   IVV K +C   +  +N  +C+  D  GIIRP++++  NT+T
Sbjct:   36 SSKETITNSMNQTNFRGCFRSVIYKNGEIFVPMLMTKSTK---YVRSELPIQSNLRNCDYKLLQPRLNINSAKINSFVSFTKPGNYLRITGWKVVLHGEITFTLRTTTLNGLIIYSNSVSENEMFPRKVNEPNLLENIQDMKQTGFDIFALELRLGRLHFLLNTGSGIVQPEFDKKYFESESKGFISDGKEHTIQIVFDEGDLTINVDGENFVTHGIEIKTYKYLNLNEHFYIGGLPESMRQINSFISPEVWSAQLRQDFVGCLGNFIVNNRLWDVDLERRPCWSKPFVESGCEFSLS-TDLCTDKPCKNNGQCFSNWNIFECDCSYTNFSGKTCTENPTIVSLNGFQWLWVKFSPLPIQSSVEELTLRFRTKHKNGFLLTTRSSILSAPDCLELKIISGYLVLIYNLGESDNMYHNPVYVSNDQWHTVKVYRRQNFLNFSVDNLLQTFDIPNDGRFLSHRHMIFGASEDLLTDQLIDSSTHFRHIKQINNLNLHVFIGYLMVFLFNGVDFLRTAQNLKHDPSLYIWKDKLDITATQSDYEPILELPVTFIDKDSSIELQLKHPTSEFILEMWIKWK-KYGTILFLQDGYGQNFILELTDGRLQFIHENNEQAEKHFINANQKLIEREWYHLKVIKK-ELIQSILIQVNDQS------TYVKLNNSKYFTLKTITIGSQSKRKSNYITYDNYMQGTTGFQGCLASFLLNYSIDYGHLPLNIEFNNNKSLPKYRLNYLYSNETQTVDW---HNIQMGCHHLDSKHQELNHCLENPCHFNGMCKQQWNSVTCDCSLTGFTGKFCDNPGTSVLLSELPRRYAIFELNSPQNTTLDRLAFGIQIINPGSMSLLHIQGQGQSSDYIQLSVLHNKSKNQLNLLVRYNMGGGTQTLFQPNVNFDDGHFHIVQFIRHESKGILWIDFQHEITKPIEDQNNKHFNLLKRIYFGE---PLKTNEKLIQNNVSELITKEGFEGFITGLNFNSINLIDLLNGNMIPGIYLKTRVNIKLNPNFKPNMEKLHAHKKRIEPETTNQNEANDMQLTATDIHDKSIDYKTQSIVVPKKDCLKYDNNYNYKECQPVDMDGIIRPLITFNDNTLT 1113

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BLAST of neurexin-1 isoform X19 vs. TrEMBL
Match: A0A3P8G6Q0 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS19036 PE=4 SV=1)

HSP 1 Score: 388.267 bits (996), Expect = 1.060e-110
Identity = 319/1154 (27.64%), Postives = 539/1154 (46.71%), Query Frame = 1

Query:  292 DAINLEFKTKQDFSHIF---YVGTQPSHSKTGL-QYILMYLDDRQLGIRI------KHDRLPESTFK--VTCVSIYSTCTDNRWHTISVSRKKTS---EKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFD-KCSDLFIIKP------------ISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKS---------------------ETSQLNQFDFYAFEIRESFLHFSINTGSGVYQ--------QKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSL--YKTLDTTRDLYIGGIPETLV---SFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYE-------TDKFSRY--------------FTGYMMHFTFNGINYFELAK--EESPS------NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED------HNYQVSCR-------------PNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPA-YLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDS---FSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQ 3402
            + I  EF+T+++   IF     G    H+K  +  Y+L YL +  L + +      K   L  +  +  ++C+S Y TC D +WH I +  KK       +S  Q+ +       ++  R++ L  + L +   TF   IP              + NLTNF+GC Q IIY +    + +L+  K  +Y  ++  I  + +  D  +++P            +SFT   SY+ + GW     G++ F  +T   N L+ Y  S                     E  Q   +D +A E+R   +HF +NTGSG+ Q        +  S   +SDG  H +++ F++G++ + +D +  + H   +  YK L+     YIGG+PE++    SF+   +WS  LRQ FVGCL +  VN   +D+ L+         V       +    C  +PC + G+CI  +N + CDCS TN++G TC     +V F+GFQ + I   P   Q+  E++TLRF T   NG  + T+S +  A D LE+ + +G L+++ N G  + I  +     D  WHT+K+ RRQ  +   +D++ + ++     + LS+  + +G  E        D  +++              F GY+M F FNG+++   A+  +  PS       +++TAT  + EP  E P++F + +S I +       +F L   IK +   G+VL L       LILE + G L L+    +   K  + +  ++    W+ + +I++ S +     R+++Q    + +I       N+ + + + +GS     S  +   + +  + GF+GC++SF  N +      S+   L     +   V      D      HN Q+ C               N C   G C+QQW  I CDC++T F G+ CDK   +++ +++P  Y +++L+  +NTTLD+LAFGIQ +   + S+I I+G G+  DFI   ++ +K +  L + +N+G G   L + +VN  DG +H V F R    + L +D  + I    + + + HFN  + IY G+   P  +   SV N+  F S   F G+++GL  N I L D++      GI L  R N+ +   F PN +
Sbjct:   20 EKIFFEFRTRKESQIIFSFELTGILTQHTKMKVDSYLLGYLLNGALVVNLFNHFSEKRSYLNHANTQKIISCISDYDTCADTQWHQILLMIKKNDILIVLDSQPQVKVNPFGQDGLITIRVMHLGGSFLNTSKETFTRFIPS-------------IGNLTNFRGCFQSIIYKSVELFIPLLS-TKNTKYIQSQIPIQSNLRNCDYKLLQPERNINHLKLNSYVSFTKPGSYLRITGWKIVLHGEITFILRTTTLNGLIIYSNSINEYELFPKVINEPNLLENIHEVKQTG-YDIFALELRLGRIHFLLNTGSGIVQPEFDKKYFESESKGFISDGKEHSIQIVFDEGDLTINVDGENFVTHGTGIKTYKYLNLNEYFYIGGLPESVRQINSFISPEVWSAQLRQDFVGCLGEFIVNERLWDIDLERRPCWSKPFVENGCKLSSSIDFCTEKPCRNKGQCISSWNIYECDCSNTNFSGKTCTENPIVVSFDGFQWLWIKFSPLPIQTSVEELTLRFRTKYENGFLLTTRSSILSAPDCLELKIISGYLSLIYNLGAVDNIYHNPVYIADDQWHTVKIYRRQNVLNFSVDNLFQTFDIPKDGRYLSHRHLILGNSEDSLTNQLIDTPTQFNHNIKQISNLNVHVFIGYIMVFLFNGVDFLRTAQNLKHDPSLYIWKDKLDITATQSNYEPNHELPLTFNNKDSTIEIQLEHSTSEFILGMWIKWKK-YGTVLILQDGFRQNLILESIDGRLQLIHMNNDQAEKYSIGENQRVVVREWYHIEVIKQES-TKLILIRVNNQSTIVKMNIS------NYFALKTINIGSLSTRNSNYDTYSNYMQRTTGFQGCVASFSFNYSIDYDQSSLNIKLNDTTPSRYHVNYLYSNDTQKVSLHNIQMGCHFSNTKHLDLNQCSENPCRFNGICMQQWNSITCDCSLTGFTGKFCDKAGTSVRLSEFPRRYAVFELNSPQNTTLDKLAFGIQITNPGTMSLIHIQGQGQSPDFIQLSVLYNKDQLNLHVRFNMGGGTQTLFQPNVNFNDGHFHIVQFIRQEAKSILLVDFQHEITKLTEDQNNKHFNLLKRIYFGEA--PKMKEKLSVNNNSEFTSRKGFEGFITGLNLNNINLIDLLYGNMIPGIYLKTRENIELNPNFKPNMK 1148

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BLAST of neurexin-1 isoform X19 vs. Ensembl Cavefish
Match: ENSAMXT00000011949.2 (pep primary_assembly:Astyanax_mexicanus-2.0:6:20986441:21378525:-1 gene:ENSAMXG00000011628.2 transcript:ENSAMXT00000011949.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 355.14 bits (910), Expect = 3.213e-101
Identity = 326/1265 (25.77%), Postives = 547/1265 (43.24%), Query Frame = 1

Query:  178 LISFVIIHTGTTEEIPVATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ----------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDIS----VNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDME-KKYNFSGSSKLLSNDIIAVG----KYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRS-----NVYVEN--KFIPNFQSK----QSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            L   ++   G   E  VATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +    I   KC ++  + P++F T  S++TL+ W   + G + F F+T E N LL +   +  Q  Q           DF+A E+ +  L+  ++ GSG  + K  +  V+DG  ++V    +  +  + +++ +   +     + LD    LY+GG+PE     + P  +W+ +L  G+VG +  I+      G  F +AL  +S                       PC++ G C  G+NR++CDCS T Y G +C R A ++ ++G + M I +P    +E EDV+LRF + R  G+ + T SR S  + RLE  L+ G++ + +N           +G + I +  N  D  WHT+++ RR  S+ L++DD++  +   +G    L    I  G    K         F G++    FNG++Y +L K       E+ A IG      + P++F S +SY+ LP +  Y    L    KT +  G +L   G   D++++E+V GY++ + + GNG +  K      ++DN WH V++ R+ +        + +  I  +   +   G  N +   +LF+G   K + K   +   V S +GF+GC++S  +N            +LL+ AL   G VE   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C+    T  F      ++Y   P    +T  D LA G  T    +  + +    G   D++  ++ K   R +    +N+G+    + E+S  + DG YH V F R+G  A+LQ+DD   I   P G+    FN Q TI +G +    +R  R          F G LSGLY+N              G+K+LN +     NV VE   + + +  S     QS  S  G +        +      SN    +   + D  +  SA              +  + I          E          KS E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  239 LAHLMMADQGMVREEYVATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNAWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDAKMKVSGIVAFKCENVATLDPVTFETPESFVTLSKWTAKKAGSISFDFRTTEPNGLLLFSHGKPKQQQQKDPKGPKTMKVDFFAIEMLDGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISVNSVRTPYNAPGESEILDLDDVLYLGGLPEDRAGLVFPTEVWTALLNYGYVGYIRRIAEAQRAVGSSFLVALGKKSN----------------------PCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSYDGSKFMKIKLPVVMHTEAEDVSLRFRSQRAYGVLMATTSRNSADTLRLE--LDGGRVRLTVNLDCIRINCTTSKGPETIFAGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNIETGIITEKLYMPAVPSNFIGHLQGLGFNGMSYIDLCKNGDIDYCELNAMIGYKSIVAD-PVTFKSRSSYVTLPTLQAYYSMHLFLQFKTTSPDGLILYNRGDGNDFIVVELVKGYMHYVSDLGNGAHLIKGNSNTPLNDNHWHNVMISRDTNN-------LHTVKIDTKITTQTTMGAKNLDLKGDLFVGGVSKEMYK--DLPKLVHSKEGFQGCLASVDLN--------GRLPDLLSDALTTMGQVERGCEGPS--TTCQEDSCSNQGVCLQQWEGFTCDCSMTSFGGPLCNDAGTTYIFGRDGGLIVYTWPPNDRPSTRADRLAVGFSTQQKDAVLVRVDSSSG-LGDYLQLQIEKGNIRVV----FNVGTDDINIEETSKFVNDGKYHIVRFTRSGGNATLQVDDLPVIERYPTGRQLTIFNSQTTIKIGGW----ERGSR---------PFQGQLSGLYYN--------------GLKVLNMAAEGDPNVRVEGSARLVGDLPSSSITPQSSASATGNRSETSPSLTDITTTTASNRQGKQTTTSQDDLLVASA-----------ECPSDDEDIDPCDPTSGGLEQCGRGGKKPKKSPEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1398

HSP 2 Score: 97.8265 bits (242), Expect = 5.773e-20
Identity = 191/897 (21.29%), Postives = 341/897 (38.02%), Query Frame = 1

Query:  847 CSDLFIIKPISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCG--------------RVAPLVKFNGFQQMIINM-PNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAK--EESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYV--STKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHF-NQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            C  + I   + FT  E  +     W    + ++ F+ KT  S+ LL Y   E       DF    I    +    +         +S T V+D   H V +     N  + +D + K     S  + +     +++GGIP  L S       + I  Q  + G + ++ VN  +  +     S+ IT  V  C  D     +C N     G C I  ++ ICDCS T + G  C               R   +  F G +    ++ PN  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D  WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++  ++  + ++V+  +    E      P++F +  S++ L K        + F  +T    G +L  +GK                 D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S  + R      GE   ++L          + L+LG   +  +        V  ++ +   ++  Y+   + +  + ++V  + L +AL                   + N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  KL    +T  ++++   ++       +     +       + RL  D GR  L +  +        S     + +  N+ D  +H V   R G    L +DD         G  T + F N +  I   K   P               +F G+L GL FN +   D+  N
Sbjct:   19 CCLVDIGASMEFTGAEGQWARFPMWNACCESEMSFNMKTKSSHGLLVYFDDE----GFCDFLELLIHNGRISLRFSIFCAEPATVLSDTAVNDSRWHAVTVRRNFKNTTLVVDDEIKWVEVKSKRRDMTVFSPMFLGGIPPELRSVALRLTSASIKDQVPYKGWITNLKVNDSEPAIV---SSDGITSNV--CEAD----HVCLN----GGVCSIVNDQPICDCSETGFQGKDCSEGLAHLMMADQGMVREEYVATFKGSEYFCYDLSPNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDAKMKVSGIVAFKCENVATLDPVTFETPESFVTLSKWTAKKAGSISFDFRTTEPNGLLLFSHGKPKQQQQKDPKGPKTMKVDFFAIEMLDGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISVNSVRTPYNAPGESEILDLD---------DVLYLGGLPEDRAGL------VFPTEVWTALLNYGYVGYIRRIAEAQRAVGSSFL-VALGK-----------------KSNPCLNSGTCREGWNRYVCDCSGTGYLGRSCERDATILSY-DGSKFMKIKLPVVMHTEAEDVSLRFRSQRAYGVLMATTSRNSAD----TLRLELDGGRVRLTVNLDCIRINCTTSKGPETIFAGQNLNDNEWHTVRVVRRGKSLKLMVDDLQPSEGQITGDHTQLEFHNIETGIITEKLYMP-----------AVPSNFIGHLQGLGFNGMSYIDLCKN 843

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Cavefish
Match: ENSAMXT00000000309.2 (pep primary_assembly:Astyanax_mexicanus-2.0:21:10525143:11115194:1 gene:ENSAMXG00000000283.2 transcript:ENSAMXT00000000309.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 350.517 bits (898), Expect = 1.760e-99
Identity = 321/1280 (25.08%), Postives = 555/1280 (43.36%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQA-----KIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQ---------FDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASP------------------------------KGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMI----DNISYAG-IKLLNRSNVYVENKFIPNFQSKQS--------ILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            VATF    Y  Y+    P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   A     K+K +    G + F KC ++  + PI+F T  ++ITL  W   + G + F F+T E N LL +      Q  +          DF+A E+ +  L+  ++ GSG  + +  +  V+DG  ++V    +     + ++  +         + LD   +LY+GG+PE     + P  +W+ +L  GFVGC+ D+ ++G   D+   AES+  TG+ S CS +   +  C + PC++ G C  G+NR++C+CS T + G +C R A ++ ++G + M I +P    +E EDVTLRF + R  G+ + T SR S  + RLE  LE G++ + +N           +G + + +  N  D  WHT+++ RR  ++ L +DD++     +G    L    I  G     ++       F G++    FNG+ Y +L K       E+ A IG      + P++F S +SYI L  +  Y    L F  KT ++ G +L   G   D++++E+V GYL+ + + GNG +  K      ++DN WH V++ R+ +        + +  I  +   +   G  N +   +L++G   K + K  ++   V + +GF+GC++S  +N            +L++ A+   G +E   E  +   +C+ + C + G C+QQW    CDC+MT+F G  C     T  F      + Y   P    +T  D LA G  T +  +  I +    G   D++  +L  +KG   +I  +N+G+    + E +  + DG YH V F R+G  A+LQ+DD   I   P                              KG+    FN Q TI +G +     R            SF G +SGLY+N + + +M      NI   G ++L+  +          +  + +S          +        P K  + ++VA + C + +   ++D     S G+  P                T P   +Y +            +E+         +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  253 VATFKGSEYFCYDLSQNPIQSSSDEITLSFKTMQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNDWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRVALQGDPKMKIH----GVVAF-KCENVATLDPITFETPEAFITLHKWNAKKTGSISFDFRTTEPNGLLLFSHGRPKQQTKEAKSPLTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAINKKVNDGEWNHVDFQRDGRAGTISVNTIRTPYQAPGESEILDLDDNLYLGGLPENKAGLVFPTEVWTALLNYGFVGCVRDLFIDGQSKDVRRMAESQKATGVKSSCSKEAPKQ--CISNPCLNNGVCREGWNRYVCECSGTGFLGRSCERDATILSYDGSKFMKIQLPVAMHTEAEDVTLRFRSQRAYGVLMATTSRDSADTLRLE--LETGRVRLTINLDCIRINCTTSKGPETLFAGQNLNDNEWHTVRVMRRGKNLQLSVDDLQ---TITGDHTQLEFHNIETGIVTEKRYLSTVPSNFIGHLQSLVFNGMAYIDLCKNGDIDYCELNAMIGFKSIIAD-PVTFKSRSSYISLTTLQAYYSMHLFFQFKTTSSDGLILYNSGDGNDFIVVELVKGYLHYVADLGNGAHLIKGNSNKPLNDNQWHNVMISRDTNN-------LHTVKIDTKVTTQTTMGAKNLDLKGDLYIGGVAKEMYK--ELPKLVHAKEGFQGCLASMDLN--------GRLPDLISDAITCVGQIERGCEGPS--TTCQEDSCANQGVCLQQWEGFSCDCSMTSFGGPLCSDAGTTYIFGRDGGRITYTWPPNDRPSTRADRLALGFSTQLKDALLIRVDSSSG-LGDYL--KLHIEKGNVAVI--FNVGTDDINIEEKAKFVNDGKYHVVKFTRSGGNATLQVDDLPVIERYPTGNIDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQTTIQIGGWDRDRSR------------SFQGQMSGLYYNGLKVFNMAVEGDPNIRIEGSVRLVGEAPSSSSITPQSSATANRSDTSTSIIETTTTTTATGRPPAKTTDDLLVASAECPSDD--EDIDPCEPSSGGLASP----------------TGPGLKVYPD-----------PVEVVRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1428

HSP 2 Score: 114.775 bits (286), Expect = 4.316e-25
Identity = 187/872 (21.44%), Postives = 336/872 (38.53%), Query Frame = 1

Query:  886 TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ-GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTF-NGINYFELAKE--ESPSNIEVTATIG-DAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG--------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTS--SQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
             E  +     W    + ++ F+ KT  S  LL Y   E       DF    +    L+   +          S   V+D   H V +     N  + +D + K     S  + +     L++GGIP  L +            Q  F G + D+ VN             ++  I++  SG V +    +   C++G  C +  ++  CDCS T Y G  C            G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D +WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    + N     EL++   +    +++   +    E      PI+F +  ++I L K +      + F  +T    G +L  +G+                D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R   Q  GE   ++L          +NL+LG   +  +      +  T+  + GF GC+   +++ Q+K V         +A +    GV   C ++   Q  C  N C + G C + W R  C+C+ T F+G  C++ +  L + D   ++  +L    +T  +++    ++       +     D       + RL  + GR  L I  +        S     + +  N+ D  +H V   R G    L +DD   I       T + F+   T  V +     +R   +V ++     F G+L  L FN +   D+  N
Sbjct:   33 AEGQWAAFPMWNACCESEMSFNMKTKASQGLLVYFDDE----GFCDFLELLMNNGKLNLRFSIFCAEPVTVFSDVVVNDSQWHGVTIKRNFKNTTLVVDREVKWAEVKSKRRDMTVFSRLFLGGIPPELRTVALRLTSDAAKEQVPFNGWITDLKVN------------NSVPAILT--SGGVDNNACGSETMCLNGGVCSVVNDKPTCDCSETGYQGKDCSEGLAHMMMGDQGKEEYVATFKGSEYFCYDLSQNPIQSSSDEITLSFKTMQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNDWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRVALQGDPKMKIHGVVAFKCENVATLDPITFETPEAFITLHKWNAKKTGSISFDFRTTEPNGLLLFSHGRPKQQTKEAKSPLTLKVDFFAIEMLDGHLYLLLDMGSGTTKTRAINKKVNDGEWNHVDFQRDGRAGTISVNTIRTPYQAPGESEILDLD---------DNLYLGGLPENKAGLVFPTEVWTALLNYGFVGCVRDLFIDGQSKDVRR-------MAESQKATGVKSSCSKEAPKQ--CISNPCLNNGVCREGWNRYVCECSGTGFLGRSCERDATILSY-DGSKFMKIQLPVAMHTEAEDVTLRFRSQRAYGVLMATTSRDSAD----TLRLELETGRVRLTINLDCIRINCTTSKGPETLFAGQNLNDNEWHTVRVMRRGKNLQLSVDDLQTITGD---HTQLEFHNIETGIVTE-----KRYLSTVPSN-----FIGHLQSLVFNGMAYIDLCKN 844

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Cavefish
Match: nrxn3a (neurexin 3 [Source:NCBI gene;Acc:103035103])

HSP 1 Score: 348.206 bits (892), Expect = 3.171e-98
Identity = 289/1064 (27.16%), Postives = 487/1064 (45.77%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKI-KRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILL-------NFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED-------HNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTK--NTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            VATF    Y  Y+    P  S  D I L FKT Q    I + G           Y+ + L D  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   A+I       +G++ F KC ++  + PISF T  +YI+L  W   + G + F F+T E N L+ +       +K+  SQ N + DF+A E+ +  L+  ++ GSG  + K +   V+DG  ++V +  +  +  + +++ +     +   + LD   D+Y+GG+P+      LP  LW+ +L  G+VGC+ D+ ++G   D+   AE++N  GI   C+  V+ K  C + PC + G C  G+NRF+CDC+ T Y   TC R A ++ ++G   M + MP    +E EDV+LRF++ R  G+ + T SR S  + RLE+     KL + L       N  +G + + +     D  WHT+++ RR  S  L +DD   +    G    L    I  G     +F  +    F G++    FNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   +  ++DN WH V++ R+NS   +   +ID++ + +  +     G  N +   +L++      +   N +   V S +GF+GC++S  +N            +L+  AL  +G +E   E             +C+ + C + G CIQQW    CDC+MT++ G +C+    T  F      + +     +  +T  D L  G  TS+     + +    G   D++   + + K    + + +N+G+    + E+S+ + DG YH V F RNG  A+LQ+D++      P G+    FN Q TI +G              ND+    F G LSGLY+N + + +M
Sbjct:  258 VATFRGSEYFCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKS-------ADYVNLALKDGAVSLVIN---LGSGAFEAIVEPVNGKFNDNVWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDIRLELSRLARIVDPKMKIQGDVVF-KCENVATLDPISFETPEAYISLPKWNTKRMGSISFDFRTSEPNGLILFTHGKPQDRKATGSQKNTKVDFFAVELLDGSLYLLLDMGSGTIKVKATQNKVNDGAWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPDNRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKDIRQIAEAQNGAGIKPSCN-KVSGK-QCESYPCKNKGVCKEGWNRFVCDCTGTGYWSRTCEREASILSYDGSMYMKVVMPTVMHTEAEDVSLRFMSQRAYGLLMATTSRDSADTLRLELDGSRVKLTVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVIRRGKSYKLTVDDDVAEGQMVGDHTRLEFHNIETGVMTERRFVSHIPSSFIGHLQSLKFNGLLYIDLCKNGDIDYCELNARFGMRSIIAD-PVTFKAKSSYLSLATLQAYTSMHLFFQFKTTSADGIILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNLIKGNSDRPLNDNQWHNVVITRDNSNLHT--LKIDAKAVSQVVN-----GAKNLDLKGDLYIAGLGPNM--YNSLPKLVASREGFKGCLASVDLN--------GRLPDLINDALFRSGQIERGCEVGFIKADLQGPSTTCQEDSCANMGICIQQWENYTCDCSMTSYTGTQCNDPGTTYIFGKGGGTITFNWPANERPSTRTDRLTVGFSTSLKDGILVRIDSAPG-LGDYLMLHIEQGK----ISVTFNIGTVDIIVQENSIPVNDGKYHVVRFTRNGGNATLQVDNWAINEHFPAGRQLTIFNTQATITIGG-------------NDRK-RPFQGQLSGLYYNGLKVLNM 1255

HSP 2 Score: 104.76 bits (260), Expect = 5.174e-22
Identity = 156/696 (22.41%), Postives = 270/696 (38.79%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLH--FSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRE--------NSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN 2814
            W  + +  L F FKT  S AL+ Y           DF    + E  L   FSI+         VS   V+D   H+V L   +    + +D   K +      + +    DL++GG+P+ + + +  +L +      F G + D+                 +  ++S     +  +G+C   PC +G  C +     +CDCS+T Y G  C                       R   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L++G +++++N G G    I+      F+ N WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LA+   P        +   E      PISF +  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G L LL + G+G  K    + K++D  W+ V + R+        NS+ + F    +S+ +     + L  GGL  N    L L   E + +  N          G+ GCI   +++      +K + Q  +A A    G+   C +    Q    P  C + G C + W R  CDC  T +    C++ +  L ++
Sbjct:   39 WDASTRSDLSFQFKTDASTALVLYFDDG----GYCDFLQLMVVEGKLQLQFSIDCAETTV---VSDKRVNDSSWHFVSLGRYNLRTVLGVDGANKADEVRPQRQYMKIVSDLFLGGLPQDIRTSV-LTLPTAKDLPPFKGIIRDLKY------------GRKVPTLLSSQKVRMDMEGICTENPCENGGICSLVDGEPLCDCSKTEYIGRFCSEEANSIPGLAHMMMADQAKSKAREENVATFRGSEYFCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGK----SADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNVWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIVDPKMKIQGDVVFKCENVATLDPISFETPEAYISLPKWNTKRMGSISFDFRTSEPNGLILFTHGKPQDRKATGSQKNTKVDFFAVELLDGSLYLLLDMGSGTIKVKATQNKVNDGAWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYL--GGLPDNR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKDIRQ--IAEAQNGAGIKPSCNKVSGKQCESYP--CKNKGVCKEGWNRFVCDCTGTGYWSRTCEREASILSYD 689

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Cavefish
Match: nrxn3a (neurexin 3 [Source:NCBI gene;Acc:103035103])

HSP 1 Score: 345.51 bits (885), Expect = 3.010e-97
Identity = 292/1087 (26.86%), Postives = 494/1087 (45.45%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKI-KRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY-------QKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSF-LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPED-------HNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTK--NTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDY-------------------NRII----ASP-------KGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDM 3318
            VATF    Y  Y+    P  S  D I L FKT Q    I + G           Y+ + L D  + + I    L    F+     +     DN WH + V+R       S   ++       +           T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   A+I       +G++ F KC ++  + PISF T  +YI+L  W   + G + F F+T E N L+ +       +K+  SQ N + DF+A E+ +  L+  ++ GSG  + K +   V+DG  ++V +  +  +  + +++ +     +   + LD   D+Y+GG+P+      LP  LW+ +L  G+VGC+ D+ ++G   D+   AE++N  GI   C+  V+ K  C + PC + G C  G+NRF+CDC+ T Y   TC R A ++ ++G   M + MP    +E EDV+LRF++ R  G+ + T SR S  + RLE  L+  ++ + +N G+G + + +     D  WHT+++ RR  S  L +DD   +    G    L    I  G     +F  +    F G++    FNG+ Y +L K       E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++ +E+V GY++ +          K   +  ++DN WH V++ R+NS   +   +ID++ + +  +     G  N +   +L++      +   N +   V S +GF+GC++S  +N            +L+  AL  +G +E   E             +C+ + C + G CIQQW    CDC+MT++ G +C+    T  F      + +     +  +T  D L  G  TS+     + +    G   D++   + + K    + + +N+G+    + E+S+ + DG YH V F RNG  A+LQ+D++                   N+ I    A P       KG+    FN Q TI +G              ND+    F G LSGLY+N + + +M
Sbjct:  258 VATFRGSEYFCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKS-------ADYVNLALKDGAVSLVIN---LGSGAFEAIVEPVNGKFNDNVWHDVKVTRNLRQVTISVDGILTTTGYTQED---------YTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDIRLELSRLARIVDPKMKIQGDVVF-KCENVATLDPISFETPEAYISLPKWNTKRMGSISFDFRTSEPNGLILFTHGKPQDRKATGSQKNTKVDFFAVELLDGSLYLLLDMGSGTIKVKATQNKVNDGAWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPDNRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKDIRQIAEAQNGAGIKPSCN-KVSGK-QCESYPCKNKGVCKEGWNRFVCDCTGTGYWSRTCEREASILSYDGSMYMKVVMPTVMHTEAEDVSLRFMSQRAYGLLMATTSRDSADTLRLE--LDGSRVKLTVNLGKGPETLYAGQKLNDNEWHTVRVIRRGKSYKLTVDDDVAEGQMVGDHTRLEFHNIETGVMTERRFVSHIPSSFIGHLQSLKFNGLLYIDLCKNGDIDYCELNARFGMRSIIAD-PVTFKAKSSYLSLATLQAYTSMHLFFQFKTTSADGIILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNLIKGNSDRPLNDNQWHNVVITRDNSNLHT--LKIDAKAVSQVVN-----GAKNLDLKGDLYIAGLGPNM--YNSLPKLVASREGFKGCLASVDLN--------GRLPDLINDALFRSGQIERGCEVGFIKADLQGPSTTCQEDSCANMGICIQQWENYTCDCSMTSYTGTQCNDPGTTYIFGKGGGTITFNWPANERPSTRTDRLTVGFSTSLKDGILVRIDSAPG-LGDYLMLHIEQGK----ISVTFNIGTVDIIVQENSIPVNDGKYHVVRFTRNGGNATLQVDNWAINEHFPAGNNDNERLQMANKKIPFKYARPVEEWLQEKGRQLTIFNTQATITIGG-------------NDRK-RPFQGQLSGLYYNGLKVLNM 1276

HSP 2 Score: 110.923 bits (276), Expect = 6.726e-24
Identity = 178/800 (22.25%), Postives = 306/800 (38.25%), Query Frame = 1

Query:  916 WAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLH--FSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGR-CIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRG--NKIIRSDYNCFDGN-WHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG-------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRE--------NSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDD 3126
            W  + +  L F FKT  S AL+ Y           DF    + E  L   FSI+         VS   V+D   H+V L   +    + +D   K +      + +    DL++GG+P+ + + +  +L +      F G + D+                 +  ++S     +  +G+C   PC +G  C +     +CDCS+T Y G  C                       R   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L++G +++++N G G    I+      F+ N WH +K+ R    V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LA+   P        +   E      PISF +  +YI LPK +      + F  +T    G +L  +GK               D+  +E++ G L LL + G+G  K    + K++D  W+ V + R+        NS+ + F    +S+ +     + L  GGL  N    L L   E + +  N          G+ GCI   +++      +K + Q  +A A    G+   C +    Q    P  C + G C + W R  CDC  T +    C++ +  L + D   Y+   +    +T  ++++    +       +     D       + RL  D  R  L +  NLG G   L  +   + D  +H V   R G    L +DD
Sbjct:   39 WDASTRSDLSFQFKTDASTALVLYFDDG----GYCDFLQLMVVEGKLQLQFSIDCAETTV---VSDKRVNDSSWHFVSLGRYNLRTVLGVDGANKADEVRPQRQYMKIVSDLFLGGLPQDIRTSV-LTLPTAKDLPPFKGIIRDLKY------------GRKVPTLLSSQKVRMDMEGICTENPCENGGICSLVDGEPLCDCSKTEYIGRFCSEEANSIPGLAHMMMADQAKSKAREENVATFRGSEYFCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGK----SADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNVWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIVDPKMKIQGDVVFKCENVATLDPISFETPEAYISLPKWNTKRMGSISFDFRTSEPNGLILFTHGKPQDRKATGSQKNTKVDFFAVELLDGSLYLLLDMGSGTIKVKATQNKVNDGAWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYL--GGLPDNR-AGLIL-PTELWTAMLN---------YGYVGCIRDLFIDG----RSKDIRQ--IAEAQNGAGIKPSCNKVSGKQCESYP--CKNKGVCKEGWNRFVCDCTGTGYWSRTCEREASILSY-DGSMYMKVVMPTVMHTEAEDVSLRFMSQRAYGLLMATTSRDSAD----TLRLELDGSRVKLTV--NLGKGPETLY-AGQKLNDNEWHTVRVIRRGKSYKLTVDD 785

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Cavefish
Match: ENSAMXT00000043111.1 (pep primary_assembly:Astyanax_mexicanus-2.0:14:7993674:8103549:1 gene:ENSAMXG00000020839.2 transcript:ENSAMXT00000043111.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 330.872 bits (847), Expect = 2.268e-96
Identity = 243/867 (28.03%), Postives = 404/867 (46.60%), Query Frame = 1

Query:  226 VATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQ----KSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCM-DGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVE-DCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERC 2784
            VATF  + +  Y+    P  S  D I L F+T Q    + + G           Y+ + L    + + I    L    F+           DN WH + VSR       S   L+       +           T L S    + G  P T +D      ++      NF GC++ ++Y+ +   L++   A+++   ++ +G++ F +C D+  + P+SF T A+Y+TL  W   + G + F F+T E N LL +     +    +  + DF+A E+ E FL+  ++ GSG  + K S+  V+DG   +V    E     V ++       TN   + LD   D+Y+GG+PE     L P  +W+  LR GFVGC+ D+ V+G   DL   AE ++  G+ S C+ +   +  C+  PC   G C  G+NR ICDCS T + G  C   + ++ ++G   + + MP    +E EDV+LRF++ R  G+ + T S  S ++D L + L+ G++ + +N G+G + + +     D  WH++K+ RR  S+ L +D++  +   SG+   L    I  G     +F       F G++    FNG+ Y +  K    S  E+ A  G      + P+SF S  SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GY++ +          K   +  ++DN WH V++ R++S   +   +IDS+ + + ++     G  N +    L++G   K  S  N +   + S  G++GC++S  +N            +L+A AL   G VE  C  D     +C  + C + G C+QQW    CDC MTT+ G  C
Sbjct:   14 VATFKGNEFFSYDLSQTPIQSSTDEITLSFRTLQRNGLLLHTGKSA-------DYVNLSLKSGAVCLVIN---LGSGAFEALVEPSDGKFNDNAWHAVRVSRNLRQVTISVDGLLTTTGYTQED---------YTMLGSDDFFYVGGSPNT-ADLPGSPVSN------NFMGCLKDVVYTNNEFKLELSHLAELRDPKVSLQGDLTF-RCEDVAALDPVSFDTPAAYVTLPRWNGKKTGSVSFDFRTTEPNGLLIFSHGRVQGPRERRPRVDFFAMELLEGFLYLLMDMGSGSIKMKASTKKVNDGEWCHVDFQREGRKGSVSVNGRSMPFSTNEGSEVLDLDGDMYLGGLPEESEGLLLPPEVWTAPLRLGFVGCVRDLFVDGRSRDLRRLAELQSAVGVSSFCTRETHRR--CSAEPCAHGGHCREGWNRHICDCSGTGFLGPNCETESTVLSYDGSMFLKVLMPRAQHTEAEDVSLRFMSQRAYGLLMATTS--SESADTLRLELDGGRVKLTVNLGKGPETLYAGQKLNDNEWHSVKVVRRGKSLQLSVDNVTVEGQMSGAHTQLEFHHIETGIMTERRFISVMPSNFIGHLQGLNFNGLPYLDQCKNGDISYCELNARFGMRRIVAD-PVSFRSRPSYLALSTLQAYASMHLFFQFKTTSPDGLLLFNSGDGSDFIVVELVKGYIHYVFDLGNGPSLMKGNSDKPLNDNQWHNVVVSRDDSNVHT--LKIDSRTVTQHSN-----GARNLDLKGELYVGGVGK--SMYNSLPKLIASRDGYQGCLASVDLN--------GRLPDLIADALHKVGQVERGC--DAGPGTTCTEDSCSNQGVCLQQWEGFTCDCTMTTYGGPLC 829

HSP 2 Score: 94.3597 bits (233), Expect = 5.115e-19
Identity = 138/610 (22.62%), Postives = 242/610 (39.67%), Query Frame = 1

Query: 1612 QSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN---KIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDM--EKKYNFSGSSKLLSNDIIAVG------KYETDKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG---------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQ---GFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDS-----FSGYLSGLYFNRIPLSDMIDN--ISY 3336
            QS  +++TL F T + NG+ + T      ++D + + L++G + +++N G G     +  SD    D  WH +++ R    V + +D +     Y     + L S+D   VG             S  F G +    +      +    LA+   P  +++   T    +     P+SF +  +Y+ LP+ +      + F  +T    G ++  +G+           D+  +E++ G+L LL + G+G  K      K++D  W  V   RE  K S  +    S P       E+    L+ +   +++LG   +  S+   +  +V ++    GF GC+   +      V  +S     LA   +  GV   C  + + + S  P  C  GG C + W R  CDC+ T F+G  C+  S  L + D   +L   +   ++T  ++++    +       +     +       + RL  D GR  L +  NLG G   L  +   + D  +H V   R G    L +D+           T + F+   T                +  ++ F S     F G+L GL FN +P  D   N  ISY
Sbjct:   33 QSSTDEITLSFRTLQRNGLLLHTGK----SADYVNLSLKSGAVCLVINLGSGAFEALVEPSDGKFNDNAWHAVRVSRNLRQVTISVDGLLTTTGYTQEDYTMLGSDDFFYVGGSPNTADLPGSPVSNNFMGCLKDVVYTNNEFKLELSHLAELRDPKVSLQGDLTFRCEDVAALDPVSFDTPAAYVTLPRWNGKKTGSVSFDFRTTEPNGLLIFSHGRVQGPRERRPRVDFFAMELLEGFLYLLMDMGSGSIKMKASTKKVNDGEWCHVDFQREGRKGS-VSVNGRSMPFSTNEGSEV----LDLDG--DMYLGGLPEE-SEGLLLPPEVWTAPLRLGFVGCVRDLF------VDGRSRDLRRLAELQSAVGVSSFCTRETHRRCSAEP--CAHGGHCREGWNRHICDCSGTGFLGPNCETESTVLSY-DGSMFLKVLMPRAQHTEAEDVSLRFMSQRAYGLLMATTSSESAD----TLRLELDGGRVKLTV--NLGKGPETLY-AGQKLNDNEWHSVKVVRRGKSLQLSVDNVTVEGQMSGAHTQLEFHHIET---------------GIMTERRFISVMPSNFIGHLQGLNFNGLPYLDQCKNGDISY 599

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BLAST of neurexin-1 isoform X19 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002142.1 (pep scaffold:Pmarinus_7.0:GL476386:209124:506099:1 gene:ENSPMAG00000001935.1 transcript:ENSPMAT00000002142.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 332.798 bits (852), Expect = 2.328e-94
Identity = 288/1086 (26.52%), Postives = 490/1086 (45.12%), Query Frame = 1

Query:  217 EIPVATFLQDAYI-YNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSG-------QLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFL-TRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLN--------QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGR----------GNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIK--IDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQN---DK-----TFDS--------------FSGYLSGLYFN 3297
            E  +ATF    Y+ Y+    P  S  D I L FKT Q    I + G           Y+ + L D  + + I    L    F+     +     DN WH + V+R    + +S G       Q+V+ + VDG +          T L S    + G  P T +D       S + N  NF GC++++IY   +  L++   AK     +   GEI F  C ++  + PI+F    ++ITL  W   + G + F F+T E + L+ + + + S++         + DF+A E+ +  L   ++ GSG  + K + + V+DG  ++V    +     + +++ +         + LD   ++++GG+PE     L P  LWS +L  G+VGC+ D+ ++G   D+   AE +N  G+   C+ D   +  C++ PC + G C  G+NR++CDC+ T YTG +C R A ++ ++G   M + MP    +E EDVTLRF++ R  G+ + T SR S  + RLE+     KL I L+  R          G +I+ +  +  D  WHT+++ RR  ++ L +D         G    L    I  G     +++      F G++ +  FNG+ Y +L +       E+ A  G      + PI F +  SY+ L  +  Y    L F  K+ ++ G +L   G + DY+ +E+V G+              +R   K  ++DN WH VI+ R+N+   +   ++D+Q + +  +     G  N +   +LF+G  EK  S   ++   V S +G++GC++S  +N         +   L   +   N +   C        +C+   C + G C+Q W    CDC MT+F G  C+    T  F+     + Y   P    +T  D LA G  ++ +  + ++ ++      DFI   + + K    + + +N+G+    + E++V + DG YH   F RNG   +LQ+D++      P G      N++  +   + P+   R GR V +   DK      F+S              F G L+GLY+N
Sbjct:    3 EESMATFKGSEYLCYDLAAHPIQSSSDEITLSFKTLQRNGLILHTGK-------AADYVNLALKDGAVSLVIN---LGSGAFEALVEPVTGKFNDNNWHDVKVTRN-LRQLSSIGHAMVNKLQIVVTISVDGILTSTGYTQEDYTMLGSDDFFYVGGSPNT-ADLP----GSPISN--NFMGCLKEVIYKNSDQKLELSKLAKEGEPKMKVVGEISF-TCENVAALDPITFEAPEAFITLPKWKTKRTGSISFDFRTTEPSGLIIFTQGKVSEVKDSKGLRSRKGDFFAIELFDGHLFLLLDMGSGTIKLKATESNVNDGEWYHVDFQRDGRTGSISVNSQRSPFTAGGDNEILDLDSEVFLGGLPEDKADLLLPTELWSALLNIGYVGCVRDLFIDGQSKDVRQLAEQQNAAGVKPFCAKDSPKQ--CSSNPCRNHGVCREGWNRYVCDCTATGYTGRSCEREASILSYDGSMFMKVVMPVVIHTEAEDVTLRFVSQRAYGLLLATTSRDSADTLRLELDSARVKLTINLDCVRIKCNSTSARKGPEILYAGKHLNDNVWHTVQVIRRGKTLKLTVDGTSADGLMDGDHTRLEFHNIETGIMTERRYTSVMPSNFMGHLQNVVFNGMAYIDLCRNGDIRYCELNARFGMRTIIAD-PIIFKTRGSYLTLATLQAYTSMYLFFQFKSTSSDGLILYNSGDANDYIAVELVKGH-IHYIFDLGNGQDLIRDNSKRVLNDNRWHNVIISRDNNNIHT--LKVDTQTVSQNVN-----GARNLDLKGDLFIGGLEK--SMYAKLPKLVASREGYQGCLASLDLN-------GRLPDLLKEASYKVNEIERGC---EGPSTTCQEYSCGNQGMCVQHWATFTCDCTMTSFSGAYCNDPGTTYIFSKGGGLITYTWRPNDRPSTRADRLAVG-FSTHLKDALLVRVDSAATLGDFIELYIKQGK----VGVTFNVGTEDISVNETNVAVNDGNYHVARFSRNGGNCTLQLDNHPINERYPSGNID---NERLALARQRIPY---RLGRVVDDWLLDKGRQLTIFNSQATITIGGQDRERPFQGQLAGLYYN 1035

HSP 2 Score: 87.4261 bits (215), Expect = 1.661e-17
Identity = 115/480 (23.96%), Postives = 195/480 (40.62%), Query Frame = 1

Query: 1543 GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS-------------VILIIDDM--EKKYNFSGSSKLLSNDIIAVG------KYETDKFSRYFTGYMMHFTFNG----INYFELAKEESPSNIEVTATIGDAEPTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGK-------------SGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRE--------NSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFN 2814
            GR   +  F G + +  ++  +  QS  +++TL F T + NG+ + T      A+D + + L++G +++++N G G      + +   +N  D NWH +K+ R  RQLS             V + +D +     Y     + L S+D   VG             S  F G +    +      +   +LAKE  P    V       E      PI+F +  ++I LPK        + F  +T    G ++   GK              GD+  +E+  G+L LL + G+G  K    E  ++D  W+ V   R+        NS+ S F    D++ +   + + L  GGL  +  + L     E + +  N          G+ GC+   +++ Q+K V   +  QN         GV   C +D   Q  C  N C + G C + W R  CDC  T + G  C++ +  L ++
Sbjct:    1 GREESMATFKGSEYLCYDLAAHPIQSSSDEITLSFKTLQRNGLILHTGK----AADYVNLALKDGAVSLVINLGSGAFEALVEPVTGKFN--DNNWHDVKVTRNLRQLSSIGHAMVNKLQIVVTISVDGILTSTGYTQEDYTMLGSDDFFYVGGSPNTADLPGSPISNNFMGCLKEVIYKNSDQKLELSKLAKEGEPKMKVVGEISFTCENVAALDPITFEAPEAFITLPKWKTKRTGSISFDFRTTEPSGLIIFTQGKVSEVKDSKGLRSRKGDFFAIELFDGHLFLLLDMGSGTIKLKATESNVNDGEWYHVDFQRDGRTGSISVNSQRSPFTAGGDNEILDLDSEVFL--GGLPEDKADLLL--PTELWSALLN---------IGYVGCVRDLFIDGQSKDVRQLAEQQNAA-------GVKPFCAKDSPKQ--CSSNPCRNHGVCREGWNRYVCDCTATGYTGRSCEREASILSYD 452

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BLAST of neurexin-1 isoform X19 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004299.1 (pep scaffold:Pmarinus_7.0:GL477235:143017:163597:1 gene:ENSPMAG00000003933.1 transcript:ENSPMAT00000004299.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 122.479 bits (306), Expect = 2.175e-30
Identity = 93/354 (26.27%), Postives = 161/354 (45.48%), Query Frame = 1

Query: 1759 GRGNKIIRSDYNCFDGNWHTLKL----KRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRY----FTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXX-XXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRID--SQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCD 2787
            G+G +++ +     D  WHT+++    KRR   + L +D++ K+   +G    L    I  G     +++      F G++    FNG+ Y +L K    +  E+ A  G      + P++F + +SY+ L  +  Y    L F  KT +  G +L   G   D++ LE+V GYL+            K + E +++DN WH VI++R+ +   +     D  +Q   E  +++LK          +LF+G   +     + +   V S  GF+GC++S  +N            +LL  AL  +G +E   E       C+ + C + G C+QQW    CDC MT++ G  C+
Sbjct:    2 GKGPEVLHAGQKLNDNEWHTVRVSRRGKRRGKLLKLSVDEVSKEDEMAGDHTRLEFHNIETGIMTERRYTSVVPSNFIGHLQSLVFNGLPYLDLCKNGDVALCEINARFGLRTIIAD-PVTFRTRSSYLTLATLQAYAAMHLFFQFKTMSPDGLLLYNGGDGTDFIALELVQGYLHYAFDLGKGPSVIKGKSEGQLNDNQWHSVIVMRDANNLHTLKVDRDMATQNGNEARNLDLKG---------DLFVGGLPR--EHYSGLHKLVVSRDGFQGCLASVDLN--------GRLPDLLDDALRRSGQIERGCE--GPSTVCQDDSCSNQGLCVQQWEEFTCDCTMTSYTGAFCN 333

HSP 2 Score: 102.449 bits (254), Expect = 1.506e-23
Identity = 76/235 (32.34%), Postives = 117/235 (49.79%), Query Frame = 1

Query:  859 FIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSG--VYQQKVSSTPVSDGLSHYVKLWFEDGNVE-VQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNG---DQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTC 1542
             I  P++F T +SY+TLA         L F FKT+  + LL Y   + +     DF A E+ + +LH++ + G G  V + K S   ++D   H V +  +  N+  +++D D   ++ N   + LD   DL++GG+P    S L H L   + R GF GCL  + +NG   D  D AL+   +    I  GC G  T   +C +  C + G C+  +  F CDC+ T+YTG  C
Sbjct:  115 IIADPVTFRTRSSYLTLATLQAYAAMHLFFQFKTMSPDGLLLYNGGDGT-----DFIALELVQGYLHYAFDLGKGPSVIKGK-SEGQLNDNQWHSVIVMRDANNLHTLKVDRDMATQNGNE-ARNLDLKGDLFVGGLPREHYSGL-HKLV--VSRDGFQGCLASVDLNGRLPDLLDDALRRSGQ----IERGCEGPST---VCQDDSCSNQGLCVQQWEEFTCDCTMTSYTGAFC 332

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BLAST of neurexin-1 isoform X19 vs. Ensembl Sea Lamprey
Match: cntnap2b (contactin associated protein like 2b [Source:ZFIN;Acc:ZDB-GENE-070912-26])

HSP 1 Score: 73.9442 bits (180), Expect = 1.976e-13
Identity = 105/419 (25.06%), Postives = 161/419 (38.42%), Query Frame = 1

Query:  676 DSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESF-LHFSINTGSGVYQQKV-SSTPVSDGLSHYVKLW--FEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKG-LCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC-GRVAPLVKFNGFQQ--------------MIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFL----ENGKLNILLNF-GRGNKIIRSDYNCFDGNWHTLKLKR--RQLSV 1848
            D+D    +  S L         MQ +I  TD A    L++A  K   L+  G+ +F           + FTT +SY+            + F FKT   + ++         +   DF   +++    + FS + G+G  +  V S  P++D   H V +    ++ ++ V L   + +      + +L  +  LY+G       S   HS        GF+GC+  + +NG   DL  +A      G+  GCSG     G LC N     GRCI  YN + CDCS ++Y G +C   V    +   + Q                I  P       E V L F TT    I +         +D  E F     E+G+L I     G    I     N  +G  H L + R  R++SV
Sbjct:  676 DTDMEHWKEDSGLLGYKPHLPVMQLLIGDTDRA----LSEAAYKVGPLSCHGDRHF--------WNSVLFTTPSSYLHFPPIRAETSLDIAFFFKTTTDSGVI------LENMGASDFIRVQLKSPHEVSFSFDVGNGPVEMAVRSEQPLNDEEWHVVSVERSLKEASLRVDLLPRELVPAPAQGHTSLQLSSQLYVGS------SVSGHS--------GFLGCVRSLRINGATLDLEERARV--TPGVKPGCSGHCRSYGSLCRN----GGRCIERYNGYSCDCSTSSYNGPSCTNEVGGFFELGTWIQYDLLEDDDDEEAVAAAIREPLEDSLPGETVLLSFSTTSVPAILLYV------GTDSWEYFAVLLQEDGRLQIRYQLGGETEAIYMEPRNLANGQPHGLNVTRHGREISV 1050

HSP 2 Score: 62.7734 bits (151), Expect = 4.969e-10
Identity = 82/364 (22.53%), Postives = 142/364 (39.01%), Query Frame = 1

Query: 2092 ISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEI--VHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKA-GGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRP--NICHSGGRCIQQWIRIRCDCAMTTFIGERC-DKVSKTLKFNDYPAYLIYKL------------SPTKNTTLDE---LAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQI 3120
            + F + +SY+  P I       + F  KT  + G +L+  G S D++ +++   H                VR E  ++D  WH V + R   ++S    R+D  P   R  +   A G  +      L++GS+             V+   GF GC+ S  +N            +L   A    GV   C         CR   ++C +GGRCI+++    CDC+ +++ G  C ++V    +   +  Y + +              P +++   E   L+F   +       +      G  S    A L+++ GR  L I Y LG     +     N+A+G  H +   R+G   S+Q+
Sbjct:  731 VLFTTPSSYLHFPPIRAETSLDIAFFFKTTTDSGVILENMGAS-DFIRVQLKSPHEVSFSFDVGNGPVEMAVRSEQPLNDEEWHVVSVERSLKEAS---LRVDLLP---RELVPAPAQGHTSLQLSSQLYVGSS-------------VSGHSGFLGCVRSLRINGATL--------DLEERARVTPGVKPGC------SGHCRSYGSLCRNGGRCIERYNGYSCDCSTSSYNGPSCTNEVGGFFELGTWIQYDLLEDDDDEEAVAAAIREPLEDSLPGETVLLSFSTTSVPAILLYV------GTDSWEYFAVLLQEDGR--LQIRYQLGGETEAIYMEPRNLANGQPHGLNVTRHGREISVQV 1052

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BLAST of neurexin-1 isoform X19 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000342.1 (pep scaffold:Pmarinus_7.0:GL477011:22393:100421:-1 gene:ENSPMAG00000000299.1 transcript:ENSPMAT00000000342.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.9366 bits (167), Expect = 6.981e-12
Identity = 77/288 (26.74%), Postives = 118/288 (40.97%), Query Frame = 1

Query:  727 NFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTG--------SGVYQQKVSS-TPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDT-TRDLY-IGGIPETLVSF---LPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAES--ENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC 1542
            NF+GC++ + Y  +  NL  LA+ +    ++T G + F  C++  ++ PI+F    S + L G AW +   +    +T  +   L Y            F     R S L   ++ G         G     +S+ + ++DG  H V +      V V LD D+     +  Y  LD  T D+Y +GG P          PH          F+GCL  I +     D+ L  +    N TG      G + D+ L  N     G+C   ++ F CDC  T Y GDTC
Sbjct:   81 NFQGCLENVSY--NGVNLIDLAKRRKPAVYIT-GNVSF-ACAEPRVV-PITFPLPGSSLWLWGPAWHEALSVVLELRTWSARGTLVYTA----------FSPAGPRASSLSIGLDDGRLTVTLLQPGRDALHLSAGSDLNDGQWHSVSVSLRRNFVGVTLDGDEASAIQS--YNPLDILTGDVYYLGGCPAVAAPGQCRAPHG--------SFLGCLRSIRIAEQDLDMGLVEQGMLGNFTGAQLNTCG-ILDRCL-PNHCEHGGQCSQEWDSFFCDCDGTGYLGDTC 341

HSP 2 Score: 56.225 bits (134), Expect = 6.208e-8
Identity = 100/487 (20.53%), Postives = 175/487 (35.93%), Query Frame = 1

Query:  877 SFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIR---ESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDA-DKKIEHTNSLYKT-LDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKG-LCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGR-VAPLVKFNGFQQMIINMPNGFQS---------------ECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLE-NGKLNILLNFGRGNKIIRS----DYNCFDGNWHTLKLKRRQLSVILIID---DMEKKYNFSGSSKLLSNDIIAVGKYETDKFS----------RYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTK--EFPISFPSVNSYIRLPKIDMYGDF--KLEFLIKTRNNKGSVLQ 2205
            SF+   +Y+    +   +   + F FKTV               L    F   E++   E  L F +  G  V    VS  P++D   H V          +Q+D   +++  +     T L     L++G                   ++GF+GCL  + +NG    L  +A +  + G+  GC+G  +  G LC N     GRC+  Y+ + CDC+ T + G  C + V    +     Q  ++  +  QS               + E     F T     + +   +     S  L I LE NG L +    G G    R+      N  DG  H + + RR   ++L +D       +     +    + D + +G+   D+            R F G +    +NG    + A  + P +  V   +G   P+     P +   V+     P    + +    +   ++  N +G+ L+
Sbjct:  553 SFSNRTAYLLFPTFRGEKSADISFYFKTVAPFGTF------LENLGLQHFLRLELKSPLEVSLRFDVGDGP-VELIAVSPWPLNDDQWHRVCAERNVKRASLQVDELPRRVRRSPPDGHTRLRLNSQLFVGATASG--------------KRGFLGCLRALQMNGVTLSLEERARTA-VGGVNPGCTGHCSSYGSLCRN----GGRCVERYSGYSCDCTHTPFDGPFCTQEVGAYFEAGTVVQFSLDSESREQSIEEDEDEQAEEEDDLDEERAIFSFSTVHAPAVLLHASTHAY-PSSYLAIVLEHNGSLQLWFG-GSGTSSPRTVSAGMRNLADGQVHAVNMTRRGTLILLQLDHYLPTAHRLPTGHAPYPRAADTLYLGRVP-DEVPLEPEVAGLNWRGFGGCLSRVQYNGWAPLKAALRQGPHSSLVVTVMGRLVPSSCAAVPQTVAPVSPSTPYPWAHQHAEHLKSMCMNLQPENGQGTALR 1010

HSP 3 Score: 49.2914 bits (116), Expect = 7.781e-6
Identity = 40/159 (25.16%), Postives = 64/159 (40.25%), Query Frame = 1

Query: 2314 KIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDK 2790
             ++D+ WHRV   R   ++S    ++D  P   R         L  NS   LF+G+               +  +GF GC+ +  MN    V+     +   A+   N G    C        S   ++C +GGRC++++    CDC  T F G  C +
Sbjct:  627 PLNDDQWHRVCAERNVKRAS---LQVDELPRRVRRSPPDGHTRLRLNS--QLFVGAT-------------ASGKRGFLGCLRALQMNG---VTLSLEERARTAVGGVNPGCTGHC--------SSYGSLCRNGGRCVERYSGYSCDCTHTPFDGPFCTQ 756

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BLAST of neurexin-1 isoform X19 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007718.1 (pep scaffold:Pmarinus_7.0:GL476589:4931:52526:1 gene:ENSPMAG00000006969.1 transcript:ENSPMAT00000007718.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.2402 bits (160), Expect = 3.628e-11
Identity = 77/285 (27.02%), Postives = 122/285 (42.81%), Query Frame = 1

Query:  727 NFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAG---W---AWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHF--SINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLD--TTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDV---TDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC 1542
            NF GCM+ + Y+ ++   D+  +AK + +    G + F   +++ +I P++F +   Y+ LAG   W   A  Q   L   F+T ++  LL  Q     Q +  +     + E  LH   S+N         V+ + ++DG  H V L   D ++ V +D     EH   L   L        Y GG   T     P    S +    F+GC+  I ++    D+ L    + + G       D+   TD+ L  N     GRC+  +  F CDC  T+YTG TC
Sbjct:  198 NFLGCMENVYYNGEDVT-DLARRAKPQIHIT--GNVMFGCPAEVALI-PVTFPSPGGYLALAGHLLWPNHAQPQIQSLGLQFRTWDAAGLL-LQVVSVVQGHGVEGLRLALSEGKLHMTSSLNLQGRTELFLVTGSSLNDGEWHGVTLQARDDSLLVMVDGR---EHFVMLSPVLHLIAGNAYYFGGTNTT-----PGHPQSAVAP--FLGCMRLIHMDNQPVDITLL--QQGLLGTFINVHFDLCGLTDRCL-PNHCEHGGRCMQTWGGFSCDCQGTSYTGSTC 464

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Nematostella
Match: EDO47422 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM09])

HSP 1 Score: 94.7449 bits (234), Expect = 7.879e-20
Identity = 110/447 (24.61%), Postives = 177/447 (39.60%), Query Frame = 1

Query:  895 SYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLD--TTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMI----INMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCF-DGNWHTLKLKRRQLSVILIIDDMEK-------KYNF----SGSSKLLSNDIIAVGKYETDKFS-----RYFTGYMMHFTFNGIN-----YFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYG 2148
            SY T     W   G++ F F+T +SN LL YQ          DF    +    +   I       Q+K+     +D   H V++  E  NV   +D A  K+  + S        T R LY+   P TL   L   +        F GCL D+     +  L  +A   + +G  SGC+       L  N+    GRC     R  C+C  T Y GD CG  +    FNG   ++    I+ P G  +    +  RF T  P+G+ +      S   D + + L  G + +  + G+G   I S   C  DG WH++ + R++  V L +D  E+       +++F     G  KL        G  ++D  +     + FTG +    F+        + +   +E  +  EV+          + P+  P+ +   R+P +D+ G
Sbjct:   33 SYTTFE--PWNLHGEVSFVFRTNQSNGLLLYQDD-----GMHDFVELFLDNGNVRIKIGIDDCYIQEKLVQGSFNDFHWHRVRITREPRNVTFAVDRAWLKLPCSPSKGDKFARATGRFLYVASFPPTLGLNLNWLV--------FPGCLGDLWFTTSEQRLD-QATLRDSSGTTSGCNSPCRTPQL--NKCLHGGRCSAEIGRVECECQGTGYEGDDCGIESSSAWFNGSSYVLYDVGIHQP-GRSTLTNTIAFRFATGNPDGVIV----HSSMFDDHVVVELSKGFVRVSFDLGQGRLNITSREGCLHDGTWHSVTIHRKRRRVTLDLDKQERVTVVIPGQFSFLDFKGGQEKLY-----FCGGPDSDTLAYSYSRKNFTGIIQQLRFDEYQVIDEVFTDRVHKEFVAVGEVSNASAILSKISQNPLPLPNCSRLARVPPVDLCG 451

HSP 2 Score: 55.8398 bits (133), Expect = 1.035e-7
Identity = 75/369 (20.33%), Postives = 146/369 (39.57%), Query Frame = 1

Query: 2092 ISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG--DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAG---GLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRP---NICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKL---SPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTS 3165
            I++P   SY      +++G+    F    R N+ + L LY   G  D++ L + +G + +     + + ++   +   +D  WHRV + RE  ++ +FA         +RA ++L      G  F      FL     Y++          +   F GC+   +   ++    ++  ++       ++G    C         CR    N C  GGRC  +  R+ C+C  T + G+ C   S +  FN   +Y++Y +    P ++T  + +AF          +    +G    S      ++ +  +  + + ++LG G   +      + DG +H V   R     +L +D   R+     G+ S
Sbjct:   27 ITYPKY-SYTTFEPWNLHGEVSFVF----RTNQSNGLLLYQDDGMHDFVELFLDNGNVRIKIGIDDCYIQEKLVQGSFNDFHWHRVRITRE-PRNVTFAV--------DRAWLKLPCSPSKGDKFARATGRFL-----YVASFPPTLGLNLNWLVFPGCLGDLWFTTSEQRLDQATLRD-------SSGTTSGC------NSPCRTPQLNKCLHGGRCSAEIGRVECECQGTGYEGDDCGIESSSAWFNGS-SYVLYDVGIHQPGRSTLTNTIAF--------RFATGNPDGVIVHSSMFDDHVVVELSKGFVRVSFDLGQGRLNITSREGCLHDGTWHSVTIHRKRRRVTLDLDKQERVTVVIPGQFS 354

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Nematostella
Match: EDO46873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNK6])

HSP 1 Score: 83.5741 bits (205), Expect = 3.258e-16
Identity = 84/336 (25.00%), Postives = 146/336 (43.45%), Query Frame = 1

Query: 1021 DFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTL-DTTRDLYIGGIP----ETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRV----APLVKFNGFQQM----IINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNK-IIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSS--KLLSNDIIAVGKYET-DKFSRYFTGYM 1977
            DF +  +RE  + F  + GSG    + SSTP+   + H + +  +     + LD    +  T+    +L    +++Y+GG+     +  +  +PH         GF GC+ ++ VN  +  L       N+      C        LC N     G C    + + C C+   YTG  C R     AP    +GF +     I++  +G  +E E     F T   +G+ +  +       D + I L +G L +  + G G + +IRS     DG WH++K  R+ L+  L +DD E K   +  S  + L++D++ +G   T D+  R+ +G +
Sbjct:  337 DFISLSLREGIVEFIFDCGSGPAVIR-SSTPIMADIWHTIVISRDGRTGGLSLDGGPPVVGTSPGRMSLISLEQEVYLGGMADYKQQPAIVDMPH---------GFNGCIQEVKVNSRELHLPSARSGLNVLN----CDHICVTHLLCFN----GGTCQAKMDHYKCHCA-VGYTGMMCERARRVSAPTFAGDGFMKFKGSEILSRLSGKNTELE---FLFRTQESSGLLLSVQKESVSHGDHITIGLIDGILEVRYDLGVGRETVIRSTATLDDGYWHSVKFVRKSLAAYLKVDD-EIKAGIASDSQYRQLNSDVLFIGGAPTVDR--RFMSGLV 647

HSP 2 Score: 62.003 bits (149), Expect = 1.260e-9
Identity = 99/417 (23.74%), Postives = 164/417 (39.33%), Query Frame = 1

Query: 2017 AKEESPSNIEV------TATIGDAEPTKEFPISFPSV--NSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYG----KSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHN----YQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDK----VSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIE--YNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVG 3201
            A+E+S S  E       T +I  AEP        P     SY+ LP++        E  I  + + G  L LYG    K  D+L L + +G++   F+ G     +VR    I  N WH V++ R+   +      +D+   G+     LK      +    LFLG   +    T+   D V    GF GC+ SF ++      ++++   + +  +   G   DC   HN    Y VS  P                 C C + T+ G  C+     V  +     Y  Y  +  S  +  T+  +      S          + DGK +DFIS  L +       I+E  ++ GSG   ++ SS  I    +H +   R+G    L +D    ++ +  G+ S+  + ++ +Y+G
Sbjct:   37 AEEQSASRPEKLANGLKTQSIEAAEPNAR-SARQPRFKGTSYMSLPRLPRSARTSFELSIMFKASSGDGLLLYGGRKDKRKDFLALGLRNGHVEFRFSCGADIA-QVRSRQNITLNQWHNVVVFRDKRDAH---LMVDN---GDLVTQSLKGTQSMMDLKTRLFLGGVPRMRRVTS---DAVPYHSGFTGCVKSFVVDGRMLDLSQALGDVVKSRQVEECGESRDCECHHNAPCHYAVSGEPI----------------CACPLGTY-GRLCEHDFKLVMPSFSGQSYLTYPSFGQSTLRTFTISLVL--KPRSDTGLILFNSQKKDGK-TDFISLSLREG------IVEFIFDCGSGPA-VIRSSTPIMADIWHTIVISRDGRTGGLSLDGGPPVVGTSPGRMSL-ISLEQEVYLG 414

HSP 3 Score: 61.6178 bits (148), Expect = 1.803e-9
Identity = 128/588 (21.77%), Postives = 234/588 (39.80%), Query Frame = 1

Query: 1543 GRVAPLVKFNGFQQM-IINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDME-KKYNFSGS-------SKLLSNDIIAVGKYETDKFSRY--FTGYMMHFTFNGINYFELAK-----------EE------------SPSNIEVTATIGDAEP--------TKEFPISFPSVN--SYIRLPKI--DMYGDFKLEFLIKTRNNKGSVL---QLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFEN-LFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGV-VEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAM--TTFIGERCDKVSKT-------LKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDD 3126
             R A   +F G   M +  +P   ++  E +++ F  +  +G+ +    R     D L + L NG +    + G     +RS  N     WH + + R +    L++D+ +    +  G+       ++L    +  + +  +D    +  FTG +  F  +G    +L++           EE            +P +  V+     A P          +F +  PS +  SY+  P         F +  ++K R++ G +L   Q      D++ L +  G +  +F+ G+G    +R    I  +IWH +++ R+          +D  P      +    G ++  S E  ++LG    Y     Q    V    GF GCI    +N  +           L +  A +G+ V +C  DH   +     +C +GG C  +    +C CA+  T  + ER  +VS         +KF    + ++ +LS  KNT   EL F  +T   +   + + +      D I+  L+      +L + Y+LG G   ++ S+  + DG++H V F R    A L++DD
Sbjct:   64 ARSARQPRFKGTSYMSLPRLPRSARTSFE-LSIMFKASSGDGLLLY-GGRKDKRKDFLALGLRNGHVEFRFSCGADIAQVRSRQNITLNQWHNVVVFRDKRDAHLMVDNGDLVTQSLKGTQSMMDLKTRLFLGGVPRMRRVTSDAVPYHSGFTGCVKSFVVDG-RMLDLSQALGDVVKSRQVEECGESRDCECHHNAPCHYAVSGEPICACPLGTYGRLCEHDFKLVMPSFSGQSYLTYPSFGQSTLRTFTISLVLKPRSDTGLILFNSQKKDGKTDFISLSLREGIVEFIFDCGSGPAV-IRSSTPIMADIWHTIVISRDGRTG---GLSLDGGP----PVVGTSPGRMSLISLEQEVYLGGMADY----KQQPAIVDMPHGFNGCIQEVKVNSRE-----------LHLPSARSGLNVLNC--DH---ICVTHLLCFNGGTCQAKMDHYKCHCAVGYTGMMCERARRVSAPTFAGDGFMKFKG--SEILSRLS-GKNT---ELEFLFRTQESSGLLLSVQKESVSHGDHITIGLID----GILEVRYDLGVGRETVIRSTATLDDGYWHSVKFVRKSLAAYLKVDD 610

HSP 4 Score: 57.7658 bits (138), Expect = 3.193e-8
Identity = 72/322 (22.36%), Postives = 124/322 (38.51%), Query Frame = 1

Query:  895 SYITLAGWAWAQKGKLQFS--FKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLD-ADKKIEHTNSLYKTLDTTRDLYIGGIPE---TLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRP---NGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKR 1833
            SY++L     + +   + S  FK    + LL Y   +     + DF A  +R   + F  + G+ + Q + S   ++    H V ++ +  +  + +D  D   +        +D    L++GG+P         +P+         GF GC+    V+G   DL+        +  V  C G+  D     N PC     + G    IC C    Y G  C     LV  +   Q  +  P+  QS     T+  L  +P    G+ +    +  G +D + + L  G +  + + G G  +IRS        WHT+ + R
Sbjct:   76 SYMSLPRLPRSARTSFELSIMFKASSGDGLLLYGGRKD---KRKDFLALGLRNGHVEFRFSCGADIAQVR-SRQNITLNQWHNVVVFRDKRDAHLMVDNGDLVTQSLKGTQSMMDLKTRLFLGGVPRMRRVTSDAVPY-------HSGFTGCVKSFVVDGRMLDLSQALGDVVKSRQVEEC-GESRDCECHHNAPCH--YAVSGEP--ICACPLGTY-GRLCEHDFKLVMPSFSGQSYLTYPSFGQSTLRTFTIS-LVLKPRSDTGLILFNSQKKDGKTDFISLSLREGIVEFIFDCGSGPAVIRSSTPIMADIWHTIVISR 379

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Nematostella
Match: EDO36419 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIM8])

HSP 1 Score: 76.6406 bits (187), Expect = 1.985e-15
Identity = 71/231 (30.74%), Postives = 106/231 (45.89%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADK---KIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISV---NGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTC 1542
            +SF   ++S+     W  +  G L FSFKT   +ALL YQ          D++  E++   L  +I TG    Q  + +  ++D   H V +  E   + + LD      KI   N   K  + +R LY GG+P +L S    S  + +  + F GC+ D+ +   NG Q +L L  ES+   G V GC      +  C + PC + GRCI       CDCS T + G+ C
Sbjct:    1 VSFVDPKSSFAQHQQWRVSSNGTLTFSFKTFLKDALLIYQDDGV-----MDYFNLELKVGRLLLNIRTGRKTSQVTLGNQ-LNDLSWHQVSIHVEHVKIGLTLDDHTRVVKIPRKNLALKN-NPSRYLYFGGLPRSL-SISTLSFPAVVFAKRFTGCIKDVEIQTGNGVQEELRL-VESK---GRVRGC------RNACRSNPCQNGGRCINKIWSSACDCSGTGFYGNQC 213

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Nematostella
Match: EDO36109 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJJ6])

HSP 1 Score: 76.2554 bits (186), Expect = 5.731e-14
Identity = 101/402 (25.12%), Postives = 162/402 (40.30%), Query Frame = 1

Query:  910 AGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFE---IRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNS-----LYKTLDTTRD-----LYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDV---TDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPN------GFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIID----DMEKKYNFSGSSKLLSND--IIAVGKYETDKFS------RYFTGYMMHFTFNGINYFE 2013
            A W +  +G   F F+T  S   L Y   E  + N + F   +     + +L F +   S V Q  +      D   H V ++   G  EV L  DK +  +       + K +   R      +Y+GGIP     +   SL     R  F GC+ ++       + A +A+ +    +  GC       T    C N    DG+CI     F CDC  T Y G  C + + +V  NG    I   PN       +  +   ++ R +   PNGI +    R    +D   I L N  + + +N G G+ I++S+       ++ +++ RRQ  V+L I+     M+ +   S SS  L  D  +  +G    +  S      R F+G++  F F  IN F+
Sbjct:   41 APWNFTTEGTFSFMFRTNTSKGALLY--GEVKKGNHYLFITLDGGIALQFYLTFCL---SYVTQLDIPGN-FYDDQWHEVAVFL--GLNEVTLTVDKILSASTECKPDIIEKEIAKERGKRWHLMYLGGIPIPSKEWKFPSLQFNYFR--FYGCIGNLMYQ-KGIEKAFRAKLKEKVLVKHGCENACISRTQSSRCRN----DGKCIDHIKTFECDCEGTGYEGKYCDQESSMVFING-STYITYTPNQTNPYADWSMKVNQLSFRMVAKNPNGIVLYMGDR---EADHFLIELVNAAIRLSVNLGGGSLILQSNVTLNMSAYYWVQVTRRQRKVLLDINYGWVQMQAETPGSLSSLDLKGDSRVAYIGGGPGNIVSPLSLSKRNFSGFLQQFVFEEINVFD 423

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Nematostella
Match: EDO39258 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAQ4])

HSP 1 Score: 73.9442 bits (180), Expect = 2.898e-13
Identity = 83/346 (23.99%), Postives = 137/346 (39.60%), Query Frame = 1

Query: 1792 NCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSND-IIAVG--------KYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAE---PTKEF-PISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFEN-LFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCD 2787
            N  D  WHT+K+ R Q S++L +D+ E + N +GS   L  D  I VG         Y   + +  F G +    F+ I+    A+ E    +   +T G      P  ++ P+ FPS+N+++RL  +    +F +    +T +  G VL     +   + L +VH  L L    G     K+     ++D +WH V               +D +P    A+  LK    N   F    ++GS               T   GF GC+++  +N    V  + + + +    +    +             C PN C +GG C + W    CDC  T + G  C+
Sbjct:   12 NLDDNKWHTVKVARNQRSLLLTLDNKETRTNTAGSFVRLDLDKFIFVGGVDRSLPDDYHGARDAPNFKGCLKDVYFDFIDILYGAQYE----LLYYSTYGRLSYICPLDDYTPVGFPSLNTHLRLTDLSP-NNFTVWLSFRTYSGDG-VLAFKMSTDARVYLSLVHAKLELEIRIGTDRPIKISLGENLNDGLWHDVT---SGINRKELWLTLDDKPEVRHANPWLK----NIGKFRRRTYIGSG--------------TQKTGFVGCMNNIKLNGA-LVRPRKLSKEVAGAVIGRCSITS----------KCFPNPCQNGGACKESWDSYTCDCQGTFYEGATCE 319

HSP 2 Score: 73.1738 bits (178), Expect = 5.728e-13
Identity = 86/363 (23.69%), Postives = 149/363 (41.05%), Query Frame = 1

Query:  496 DNRWHTISVSRK----------KTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKR-YFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDT-TRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSG-CSGDVTDKGLCANRPCMDG-RCIIGYNRFICDCSRTNYTGDTC 1542
            DN+WHT+ V+R           K +  N++G                     V   + + I  GG+      D S+ +     ++  NFKGC++ + +      +DIL  A+ +  Y+ T G + +    D +   P+ F +  +++ L   +      +  SF+T   + +LA++ S  +++         +  + L   I  G+    +      ++DGL H V        + + LD   ++ H N   K +    R  YIG               SG  + GFVGC+ +I +NG    +  +  S+ + G V G CS  +T K  C   PC +G  C   ++ + CDC  T Y G TC
Sbjct:   15 DNKWHTVKVARNQRSLLLTLDNKETRTNTAGSF-------------------VRLDLDKFIFVGGV------DRSLPDDYHGARDAPNFKGCLKDVYFDF----IDILYGAQYELLYYSTYGRLSYICPLDDYT--PVGFPSLNTHLRLTDLS-PNNFTVWLSFRTYSGDGVLAFKMSTDARV------YLSLVHAKLELEIRIGTDRPIKISLGENLNDGLWHDVTSGINRKELWLTLDDKPEVRHANPWLKNIGKFRRRTYIG---------------SGTQKTGFVGCMNNIKLNGAL--VRPRKLSKEVAGAVIGRCS--ITSK--CFPNPCQNGGACKESWDSYTCDCQGTFYEGATC 318

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Medaka
Match: ENSORLT00000034989.1 (neurexin 1 [Source:NCBI gene;Acc:101159771])

HSP 1 Score: 357.451 bits (916), Expect = 8.353e-102
Identity = 330/1286 (25.66%), Postives = 564/1286 (43.86%), Query Frame = 1

Query:  226 VATFLQDAYIYNSINI-PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY---------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEK----YLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDD---------------------------YNRIIAS---PKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVIN------------------IWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            VATF    +    +++ P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +   G + F KC ++  + PI+F T  S+I L  W   + G + F F+T E N LL +         + S++ Q  + DF+A E+ E  L+  ++ GSG  + K  +  V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE  +  + P  +W+ +L  G+VGC+ D+ ++G   D+   AE +  TG+   CS + + +  C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G + M + +P    +E EDV+LRF + R  GI I T SR S  + RLE  L++G++ + +N           +G + I +  N  D  WHT+++ RR  S+ L +DD+   +   +G    L    I  G     +F       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      + DN WH VI+ R+ +        + +  I  +   +   G  N +   NL++G   K    YL K       V + +GF+GC++S  +N            +L++ AL   G +E   E  +   +C+ + C + G C+QQW    CDC+MTTF G  C+    T  F      + Y   P    +T  D LA G  T +  +  + +    G   DF+  +L  DKG+  ++  +N+G+    + E +  + DG YH V F R+G  A+LQ+DD                             R++      KG+    FN Q TI +G +           + D++  SF G LSGLY+N + + +M              SNV ++        S  SI  +     N      + + +  +  S                       S ++   T  +   TT D  + +    S+   I    E ++ G+ N                    +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  263 VATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNDWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAF-KCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDVRRLAEIQKATGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSYDGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSADTLRLE--LDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMSTVPSNFIGHLQSLSFNGMSYIDLCKNGDIDYCELNAMIGFKNIIAD-PVTFKSRSSYVTLTTLQAYYSMHLFFQFKTTSPDGLILYNSGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNKPLSDNQWHNVIISRDTNN-------LHTVKIDTKITTQTTTGAKNLDLKGNLYIGGVAKDMYMYLPKL------VHAKEGFQGCLASVDLN--------GRLPDLMSDALDCVGQIERGCEGPS--TTCQEDSCANQGVCLQQWEGFSCDCSMTTFGGPLCNDAGTTYIFGRDGGLITYTWPPNDRPSTRADRLAIGFSTHLKDAVLVRVDSSSG-LGDFL--KLHIDKGKVAVV--FNVGTDDINIEEKAKFVNDGKYHIVKFTRSGGNATLQVDDLPVNERYPTGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQTTIQIGGW-----------ERDRS-QSFQGQLSGLYYNGLKVFNMAAE---------GDSNVKIQGSVRLVGDSPSSITPQSSTTANRSETSTSIMEITTTTAS-----------------------SRRVKQTTPREPQQTTDDFLVASAECPSDDEDI-DPCEPSSGGLANPTFAGPNPPEIIREASSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1451

HSP 2 Score: 124.02 bits (310), Expect = 6.024e-28
Identity = 205/898 (22.83%), Postives = 343/898 (38.20%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ--GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG--------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  S+ LL Y   E       DF    IR   L    +         +S T V+D   H V +     N  + +D + K     S  + +     L++GGIP  L S +   L S  ++    F G + D++VN  +  +     SE +   + G +       +C N     G C +  N   CDCS T + G  C                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D +WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I  T            PI+F +  S+I L K +      + F  +T    G +L  +GK                D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   ++L      GGL  N    +F    E + +  N          G+ GCI   +++ Q+K V      + L  I  A  GV   C ++ + Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       I     D       + RL  D GR  L +  +        S     + +  N+ D  +H V   R G    L +DD + I     G  T + F+   T  V +  F +              +F G+L  L FN +   D+  N
Sbjct:   28 LEFTGAEGQWARFPVWNACCESEMSFNMKTKSSHGLLVYFDDE----GFCDFLELLIRNGKLSLRFSIFCAEPATVISDTAVNDSRWHTVTIRRNFKNTTLMVDNEIKWVEVMSKRRDMTVFSHLFVGGIPPELRS-VALRLTSAAVKDEPPFAGWITDVTVNNTECAI---INSEGVLMDICGTA------NMCQN----GGICSLIDNEPTCDCSHTGFQGKDCSEEDNYTEGLAHLMMGDQDRIKGKEEYVATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNDWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAFKCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVF--PTEVWTALLN---------YGYVGCIRDLFIDGQSKDV------RRLAEIQKA-TGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSY-DGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSAD----TLRLELDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMS----------TVPSNFIGHLQSLSFNGMSYIDLCKN 866

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Medaka
Match: ENSORLT00000046931.1 (neurexin 1 [Source:NCBI gene;Acc:101159771])

HSP 1 Score: 357.451 bits (916), Expect = 1.033e-101
Identity = 330/1286 (25.66%), Postives = 564/1286 (43.86%), Query Frame = 1

Query:  226 VATFLQDAYIYNSINI-PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY---------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEK----YLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDD---------------------------YNRIIAS---PKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVIN------------------IWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            VATF    +    +++ P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +   G + F KC ++  + PI+F T  S+I L  W   + G + F F+T E N LL +         + S++ Q  + DF+A E+ E  L+  ++ GSG  + K  +  V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE  +  + P  +W+ +L  G+VGC+ D+ ++G   D+   AE +  TG+   CS + + +  C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G + M + +P    +E EDV+LRF + R  GI I T SR S  + RLE  L++G++ + +N           +G + I +  N  D  WHT+++ RR  S+ L +DD+   +   +G    L    I  G     +F       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      + DN WH VI+ R+ +        + +  I  +   +   G  N +   NL++G   K    YL K       V + +GF+GC++S  +N            +L++ AL   G +E   E  +   +C+ + C + G C+QQW    CDC+MTTF G  C+    T  F      + Y   P    +T  D LA G  T +  +  + +    G   DF+  +L  DKG+  ++  +N+G+    + E +  + DG YH V F R+G  A+LQ+DD                             R++      KG+    FN Q TI +G +           + D++  SF G LSGLY+N + + +M              SNV ++        S  SI  +     N      + + +  +  S                       S ++   T  +   TT D  + +    S+   I    E ++ G+ N                    +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  273 VATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNDWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAF-KCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDVRRLAEIQKATGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSYDGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSADTLRLE--LDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMSTVPSNFIGHLQSLSFNGMSYIDLCKNGDIDYCELNAMIGFKNIIAD-PVTFKSRSSYVTLTTLQAYYSMHLFFQFKTTSPDGLILYNSGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNKPLSDNQWHNVIISRDTNN-------LHTVKIDTKITTQTTTGAKNLDLKGNLYIGGVAKDMYMYLPKL------VHAKEGFQGCLASVDLN--------GRLPDLMSDALDCVGQIERGCEGPS--TTCQEDSCANQGVCLQQWEGFSCDCSMTTFGGPLCNDAGTTYIFGRDGGLITYTWPPNDRPSTRADRLAIGFSTHLKDAVLVRVDSSSG-LGDFL--KLHIDKGKVAVV--FNVGTDDINIEEKAKFVNDGKYHIVKFTRSGGNATLQVDDLPVNERYPTGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQTTIQIGGW-----------ERDRS-QSFQGQLSGLYYNGLKVFNMAAE---------GDSNVKIQGSVRLVGDSPSSITPQSSTTANRSETSTSIMEITTTTAS-----------------------SRRVKQTTPREPQQTTDDFLVASAECPSDDEDI-DPCEPSSGGLANPTFAGPNPPEIIREASSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1461

HSP 2 Score: 119.783 bits (299), Expect = 1.279e-26
Identity = 205/908 (22.58%), Postives = 343/908 (37.78%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ--GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC--------------------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG--------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  S+ LL Y   E       DF    IR   L    +         +S T V+D   H V +     N  + +D + K     S  + +     L++GGIP  L S +   L S  ++    F G + D++VN  +  +     SE +   + G +       +C N     G C +  N   CDCS T + G  C                                G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D +WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I  T            PI+F +  S+I L K +      + F  +T    G +L  +GK                D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   ++L      GGL  N    +F    E + +  N          G+ GCI   +++ Q+K V      + L  I  A  GV   C ++ + Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       I     D       + RL  D GR  L +  +        S     + +  N+ D  +H V   R G    L +DD + I     G  T + F+   T  V +  F +              +F G+L  L FN +   D+  N
Sbjct:   28 LEFTGAEGQWARFPVWNACCESEMSFNMKTKSSHGLLVYFDDE----GFCDFLELLIRNGKLSLRFSIFCAEPATVISDTAVNDSRWHTVTIRRNFKNTTLMVDNEIKWVEVMSKRRDMTVFSHLFVGGIPPELRS-VALRLTSAAVKDEPPFAGWITDVTVNNTECAI---INSEGVLMDICGTA------NMCQN----GGICSLIDNEPTCDCSHTGFQGKDCSEGLAHLMMGDQDRIKGQRGEAWLLRSLLSTPGKEEYVATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNDWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAFKCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVF--PTEVWTALLN---------YGYVGCIRDLFIDGQSKDV------RRLAEIQKA-TGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSY-DGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSAD----TLRLELDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMS----------TVPSNFIGHLQSLSFNGMSYIDLCKN 876

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Medaka
Match: ENSORLT00000030454.1 (neurexin 1 [Source:NCBI gene;Acc:101159771])

HSP 1 Score: 356.681 bits (914), Expect = 1.700e-101
Identity = 327/1286 (25.43%), Postives = 559/1286 (43.47%), Query Frame = 1

Query:  226 VATFLQDAYIYNSINI-PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY---------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXX-XXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEK----YLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDD---------------------------YNRIIAS---PKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVIN------------------IWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            VATF    +    +++ P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +   G + F KC ++  + PI+F T  S+I L  W   + G + F F+T E N LL +         + S++ Q  + DF+A E+ E  L+  ++ GSG  + K  +  V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE  +  + P  +W+ +L  G+VGC+ D+ ++G   D+   AE +  TG+   CS + + +  C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G + M + +P    +E EDV+LRF + R  GI I T SR S  + RLE  L++G++ + +N           +G + I +  N  D  WHT+++ RR  S+ L +DD+   +   +G    L    I  G     +F       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      + DN WH VI+ R+ +        + +  I  +   +   G  N +   NL++G   K    YL K       V + +GF+GC++S  +N            +L++ AL   G +E   E  +   +C+ + C + G C+QQW    CDC+MTTF G  C+    T  F      + Y   P    +T  D LA G  T +  +  + +    G   DF+  +L  DKG+  ++  +N+G+    + E +  + DG YH V F R+G  A+LQ+DD                             R++      KG+    FN Q TI +G +           + D++  SF G LSGLY+N + + +M              SNV ++        S  SI  +     N      + + +  +  S                       S ++   T  +   TT D  + +    S+   I    E ++ G+ N                    +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  279 VATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNDWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAF-KCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDVRRLAEIQKATGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSYDGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSADTLRLE--LDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMSTVPSNFIGHLQSLSFNGMSYIDLCKNGDIDYCELNAMIGFKNIIAD-PVTFKSRSSYVTLTTLQAYYSMHLFFQFKTTSPDGLILYNSGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNKPLSDNQWHNVIISRDTNN-------LHTVKIDTKITTQTTTGAKNLDLKGNLYIGGVAKDMYMYLPKL------VHAKEGFQGCLASVDLN--------GRLPDLMSDALDCVGQIERGCEGPS--TTCQEDSCANQGVCLQQWEGFSCDCSMTTFGGPLCNDAGTTYIFGRDGGLITYTWPPNDRPSTRADRLAIGFSTHLKDAVLVRVDSSSG-LGDFL--KLHIDKGKVAVV--FNVGTDDINIEEKAKFVNDGKYHIVKFTRSGGNATLQVDDLPVNERYPTGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQTTIQIGGW-----------ERDRS-QSFQGQLSGLYYNGLKVFNMAAE---------GDSNVKIQGSVRLVGDSPSSITPQSSTTANRSETSTSIMEITTTTAS-----------------------SRRVKQTTPREPQQTTDDFLVASAECPSDDEDI-DPCEPSSGGLANPTFAGPNPPEIIREASSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1467

HSP 2 Score: 117.472 bits (293), Expect = 6.248e-26
Identity = 205/914 (22.43%), Postives = 343/914 (37.53%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ--GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC--------------------------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG--------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  S+ LL Y   E       DF    IR   L    +         +S T V+D   H V +     N  + +D + K     S  + +     L++GGIP  L S +   L S  ++    F G + D++VN  +  +     SE +   + G +       +C N     G C +  N   CDCS T + G  C                                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D +WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I  T            PI+F +  S+I L K +      + F  +T    G +L  +GK                D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   ++L      GGL  N    +F    E + +  N          G+ GCI   +++ Q+K V      + L  I  A  GV   C ++ + Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       I     D       + RL  D GR  L +  +        S     + +  N+ D  +H V   R G    L +DD + I     G  T + F+   T  V +  F +              +F G+L  L FN +   D+  N
Sbjct:   28 LEFTGAEGQWARFPVWNACCESEMSFNMKTKSSHGLLVYFDDE----GFCDFLELLIRNGKLSLRFSIFCAEPATVISDTAVNDSRWHTVTIRRNFKNTTLMVDNEIKWVEVMSKRRDMTVFSHLFVGGIPPELRS-VALRLTSAAVKDEPPFAGWITDVTVNNTECAI---INSEGVLMDICGTA------NMCQN----GGICSLIDNEPTCDCSHTGFQGKDCSEEDNYTEGLAHLMMGDQDRIKGQRGEAWLLRSLLSTPGKEEYVATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNDWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAFKCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVF--PTEVWTALLN---------YGYVGCIRDLFIDGQSKDV------RRLAEIQKA-TGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSY-DGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSAD----TLRLELDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMS----------TVPSNFIGHLQSLSFNGMSYIDLCKN 882

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Medaka
Match: ENSORLT00000033187.1 (neurexin 1 [Source:NCBI gene;Acc:101159771])

HSP 1 Score: 356.681 bits (914), Expect = 1.700e-101
Identity = 327/1286 (25.43%), Postives = 559/1286 (43.47%), Query Frame = 1

Query:  226 VATFLQDAYIYNSINI-PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY---------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXX-XXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEK----YLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDD---------------------------YNRIIAS---PKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVIN------------------IWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            VATF    +    +++ P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +   G + F KC ++  + PI+F T  S+I L  W   + G + F F+T E N LL +         + S++ Q  + DF+A E+ E  L+  ++ GSG  + K  +  V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE  +  + P  +W+ +L  G+VGC+ D+ ++G   D+   AE +  TG+   CS + + +  C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G + M + +P    +E EDV+LRF + R  GI I T SR S  + RLE  L++G++ + +N           +G + I +  N  D  WHT+++ RR  S+ L +DD+   +   +G    L    I  G     +F       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ +          K      + DN WH VI+ R+ +        + +  I  +   +   G  N +   NL++G   K    YL K       V + +GF+GC++S  +N            +L++ AL   G +E   E  +   +C+ + C + G C+QQW    CDC+MTTF G  C+    T  F      + Y   P    +T  D LA G  T +  +  + +    G   DF+  +L  DKG+  ++  +N+G+    + E +  + DG YH V F R+G  A+LQ+DD                             R++      KG+    FN Q TI +G +           + D++  SF G LSGLY+N + + +M              SNV ++        S  SI  +     N      + + +  +  S                       S ++   T  +   TT D  + +    S+   I    E ++ G+ N                    +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  279 VATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNDWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAF-KCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDVRRLAEIQKATGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSYDGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSADTLRLE--LDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMSTVPSNFIGHLQSLSFNGMSYIDLCKNGDIDYCELNAMIGFKNIIAD-PVTFKSRSSYVTLTTLQAYYSMHLFFQFKTTSPDGLILYNSGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNKPLSDNQWHNVIISRDTNN-------LHTVKIDTKITTQTTTGAKNLDLKGNLYIGGVAKDMYMYLPKL------VHAKEGFQGCLASVDLN--------GRLPDLMSDALDCVGQIERGCEGPS--TTCQEDSCANQGVCLQQWEGFSCDCSMTTFGGPLCNDAGTTYIFGRDGGLITYTWPPNDRPSTRADRLAIGFSTHLKDAVLVRVDSSSG-LGDFL--KLHIDKGKVAVV--FNVGTDDINIEEKAKFVNDGKYHIVKFTRSGGNATLQVDDLPVNERYPTGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQTTIQIGGW-----------ERDRS-QSFQGQLSGLYYNGLKVFNMAAE---------GDSNVKIQGSVRLVGDSPSSITPQSSTTANRSETSTSIMEITTTTAS-----------------------SRRVKQTTPREPQQTTDDFLVASAECPSDDEDI-DPCEPSSGGLANPTFAGPNPPEIIREASSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1467

HSP 2 Score: 117.472 bits (293), Expect = 6.248e-26
Identity = 205/914 (22.43%), Postives = 343/914 (37.53%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ--GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC--------------------------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG--------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  S+ LL Y   E       DF    IR   L    +         +S T V+D   H V +     N  + +D + K     S  + +     L++GGIP  L S +   L S  ++    F G + D++VN  +  +     SE +   + G +       +C N     G C +  N   CDCS T + G  C                                      G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D +WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I  T            PI+F +  S+I L K +      + F  +T    G +L  +GK                D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   ++L      GGL  N    +F    E + +  N          G+ GCI   +++ Q+K V      + L  I  A  GV   C ++ + Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       I     D       + RL  D GR  L +  +        S     + +  N+ D  +H V   R G    L +DD + I     G  T + F+   T  V +  F +              +F G+L  L FN +   D+  N
Sbjct:   28 LEFTGAEGQWARFPVWNACCESEMSFNMKTKSSHGLLVYFDDE----GFCDFLELLIRNGKLSLRFSIFCAEPATVISDTAVNDSRWHTVTIRRNFKNTTLMVDNEIKWVEVMSKRRDMTVFSHLFVGGIPPELRS-VALRLTSAAVKDEPPFAGWITDVTVNNTECAI---INSEGVLMDICGTA------NMCQN----GGICSLIDNEPTCDCSHTGFQGKDCSEEDNYTEGLAHLMMGDQDRIKGQRGEAWLLRSLLSTPGKEEYVATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNDWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAFKCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVF--PTEVWTALLN---------YGYVGCIRDLFIDGQSKDV------RRLAEIQKA-TGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSY-DGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSAD----TLRLELDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMS----------TVPSNFIGHLQSLSFNGMSYIDLCKN 882

[Close]

BLAST of neurexin-1 isoform X19 vs. Ensembl Medaka
Match: ENSORLT00000027034.1 (neurexin 1 [Source:NCBI gene;Acc:101159771])

HSP 1 Score: 356.681 bits (914), Expect = 1.951e-101
Identity = 330/1286 (25.66%), Postives = 564/1286 (43.86%), Query Frame = 1

Query:  226 VATFLQDAYIYNSINI-PTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLT-RGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAY---------QKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFL-PHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMD-GRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNF---------GRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEK-KYNFSGSSKLLSNDIIAVGKYETDKF----SRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXK-KVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEK----YLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPT--KNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDD---------------------------YNRIIAS---PKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVIN------------------IWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPS 3837
            VATF    +    +++ P  S  D I L FKT Q    + + G           Y+ + L +  + + I    L    F+     +     DN WH + V+R    + +  G  ++ + VDG +          T L S    + G  P T +D       S + N  NF GC+++++Y  ++  L++   AK     +   G + F KC ++  + PI+F T  S+I L  W   + G + F F+T E N LL +         + S++ Q  + DF+A E+ E  L+  ++ GSG  + K  +  V+DG  ++V    +  +  + ++  +         + LD   +LY+GG+PE  +  + P  +W+ +L  G+VGC+ D+ ++G   D+   AE +  TG+   CS + + +  C + PC + G C  G+NR++CDCS T Y G +C R A ++ ++G + M + +P    +E EDV+LRF + R  GI I T SR S  + RLE  L++G++ + +N           +G + I +  N  D  WHT+++ RR  S+ L +DD+   +   +G    L    I  G     +F       F G++   +FNG++Y +L K       E+ A IG      + P++F S +SY+ L  +  Y    L F  KT +  G +L   G   D++++E+V GYL+ + + GNG +  K      + DN WH VI+ R+ +        + +  I  +   +   G  N +   NL++G   K    YL K       V + +GF+GC++S  +N            +L++ AL   G +E   E  +   +C+ + C + G C+QQW    CDC+MTTF G  C+    T  F      + Y   P    +T  D LA G  T +  +  + +    G   DF+  +L  DKG+  ++  +N+G+    + E +  + DG YH V F R+G  A+LQ+DD                             R++      KG+    FN Q TI +G +           + D++  SF G LSGLY+N + + +M              SNV ++        S  SI  +     N      + + +  +  S                       S ++   T  +   TT D  + +    S+   I    E ++ G+ N                    +++G     +L ++ +   +Y+   +DEGSY+V++   +I  S
Sbjct:  275 VATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGKSA-------DYVNLALKNGAVSLVIN---LGSGAFEALVEPVNGKFNDNDWHDVKVTRN-LRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPST-ADLP----GSPVSN--NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAF-KCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDVRRLAEIQKATGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSYDGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSADTLRLE--LDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMSTVPSNFIGHLQSLSFNGMSYIDLCKNGDIDYCELNAMIGFKNIIAD-PVTFKSRSSYVTLTTLQAYYSMHLFFQFKTTSPDGLILYNSGDGNDFIVVELVKGYLHYVSDLGNGAHLIKGNSNKPLSDNQWHNVIISRDTNN-------LHTVKIDTKITTQTTTGAKNLDLKGNLYIGGVAKDMYMYLPKL------VHAKEGFQGCLASVDLN--------GRLPDLMSDALDCVGQIERGCEGPS--TTCQEDSCANQGVCLQQWEGFSCDCSMTTFGGPLCNDAGTTYIFGRDGGLITYTWPPNDRPSTRADRLAIGFSTHLKDAVLVRVDSSSG-LGDFL--KLHIDKGKVAVV--FNVGTDDINIEEKAKFVNDGKYHIVKFTRSGGNATLQVDDLPVNERYPTGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQTTIQIGGW-----------ERDRS-QSFQGQLSGLYYNGLKVFNMAAE---------GDSNVKIQGSVRLVGDSPSSITPQSSTTANRSETSTSIMEITTTTAS-----------------------SRRVKQTTPREPQQTTDDFLVASAECPSDDEDI-DPCEPSSGGLANPTFAGPNPPEIIREASSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNS 1463

HSP 2 Score: 118.627 bits (296), Expect = 2.585e-26
Identity = 205/910 (22.53%), Postives = 343/910 (37.69%), Query Frame = 1

Query:  874 ISFT-TEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQ--GFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTC----------------------------------GRVAPLVKFNGFQQMIINMP-NGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGN-----KIIRSDYNCFDGNWHTLKLKR--RQLS------VILIIDDM--EKKYNFSGSSKLLSNDIIAVGKYET------DKFSRYFTGYMMHFTFNG----INYFELAKEESPS-NIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSG--------------DYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKS--SSFAFRIDSQPIGERAHIELK----AGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMN-QTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNL------GSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDN 3327
            + FT  E  +     W    + ++ F+ KT  S+ LL Y   E       DF    IR   L    +         +S T V+D   H V +     N  + +D + K     S  + +     L++GGIP  L S +   L S  ++    F G + D++VN  +  +     SE +   + G +       +C N     G C +  N   CDCS T + G  C                                  G+   +  F G +    ++  N  QS  +++TL F T + NG+ + T      ++D + + L+NG +++++N G G      + +   +N  D +WH +K+ R  RQ S      V + +D +     Y     + L S+D   VG   +         S  F G +    +      +    LAK+  P   I  T            PI+F +  S+I L K +      + F  +T    G +L  +GK                D+  +E++ G+L LL + G+G  K      K++D  W+ V   R+      S    R      GE   ++L      GGL  N    +F    E + +  N          G+ GCI   +++ Q+K V      + L  I  A  GV   C ++ + Q  C  N C + G C + W R  CDC+ T ++G  C++ +  L + D   ++  +L    +T  ++++   ++       I     D       + RL  D GR  L +  +        S     + +  N+ D  +H V   R G    L +DD + I     G  T + F+   T  V +  F +              +F G+L  L FN +   D+  N
Sbjct:   28 LEFTGAEGQWARFPVWNACCESEMSFNMKTKSSHGLLVYFDDE----GFCDFLELLIRNGKLSLRFSIFCAEPATVISDTAVNDSRWHTVTIRRNFKNTTLMVDNEIKWVEVMSKRRDMTVFSHLFVGGIPPELRS-VALRLTSAAVKDEPPFAGWITDVTVNNTECAI---INSEGVLMDICGTA------NMCQN----GGICSLIDNEPTCDCSHTGFQGKDCSEEDNYTEGLAHLMMGDQGQRGEAWLLRSLLSTPGKEEYVATFKGSEFFCYDLSLNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFN--DNDWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGTVAFKCENVATLDPITFETPESFIVLNKWNAKKTGSISFDFRTTEPNGLLLFSHGKPKQQPKDSKSPQTFKVDFFAIEMLEGHLYLLLDMGSGTTKTKAVNKKVNDGEWYHVDFQRDGRSGTISINTLRTAYTAPGESEILDLDDNLYLGGLPENKMGLVF--PTEVWTALLN---------YGYVGCIRDLFIDGQSKDV------RRLAEIQKA-TGVKPSCSKEPSKQ--CLSNPCQNNGICREGWNRYVCDCSGTGYLGRSCEREATILSY-DGSKFMKVQLPVVMHTEAEDVSLRFRSQRAYGILIATTSRDSAD----TLRLELDSGRVRLTVNLDCIRINCTSSKGPETIFAGQNLNDNEWHTVRVFRRGKSLKLTVDDLSPIEGQMAGDHTQLEFHNIETGIVTEKRFMS----------TVPSNFIGHLQSLSFNGMSYIDLCKN 878

[Close]

BLAST of neurexin-1 isoform X19 vs. Planmine SMEST
Match: SMESG000058569.1 (SMESG000058569.1)

HSP 1 Score: 2471.04 bits (6403), Expect = 0.000e+0
Identity = 1273/1275 (99.84%), Postives = 1274/1275 (99.92%), Query Frame = 1

Query:  157 METINFFLISFVIIHTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHXXXXXXXXXXDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 3981
            METINFFLISFVIIHTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLVIKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQ+DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDN IYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV
Sbjct:    1 METINFFLISFVIIHTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLVIKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQYDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNGIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 1275

[Close]

BLAST of neurexin-1 isoform X19 vs. Planmine SMEST
Match: SMESG000058569.1 (SMESG000058569.1)

HSP 1 Score: 2449.47 bits (6347), Expect = 0.000e+0
Identity = 1264/1275 (99.14%), Postives = 1265/1275 (99.22%), Query Frame = 1

Query:  157 METINFFLISFVIIHTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHXXXXXXXXXXDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 3981
            METINFFLISFVIIHTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTS         IKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQ+DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDN IYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV
Sbjct:    1 METINFFLISFVIIHTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTS---------IKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQYDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNGIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 1266

[Close]

BLAST of neurexin-1 isoform X19 vs. Planmine SMEST
Match: SMESG000058569.1 (SMESG000058569.1)

HSP 1 Score: 2412.49 bits (6251), Expect = 0.000e+0
Identity = 1247/1261 (98.89%), Postives = 1248/1261 (98.97%), Query Frame = 1

Query:  199 HTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHXXXXXXXXXXDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 3981
             TG  EEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTS         IKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQ+DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDN IYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV
Sbjct:  381 ETGNPEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTS---------IKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQYDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNGIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 1632

[Close]

BLAST of neurexin-1 isoform X19 vs. Planmine SMEST
Match: SMESG000058569.1 (SMESG000058569.1)

HSP 1 Score: 2410.95 bits (6247), Expect = 0.000e+0
Identity = 1247/1261 (98.89%), Postives = 1248/1261 (98.97%), Query Frame = 1

Query:  199 HTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHXXXXXXXXXXDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 3981
             TG  EEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTS         IKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQ+DLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDN IYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV
Sbjct:  350 ETGNPEEIPVATFLQDAYIYNSINIPTVSDMDAINLEFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPESTFKVTCVSIYSTCTDNRWHTISVSRKKTS---------IKVVVDGKVVVDRMVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGDQYDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYLNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKGKTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTKKNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKITTTPDNGIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 1601

[Close]

BLAST of neurexin-1 isoform X19 vs. Planmine SMEST
Match: SMESG000066308.1 (SMESG000066308.1)

HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0
Identity = 452/1267 (35.67%), Postives = 717/1267 (56.59%), Query Frame = 1

Query:  295 AINLEFKTKQDFSHIFYVGTQPSHSK----TGLQYILMYLDDRQLGIRIKHDRLPESTF---KVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLXXXXXXXXXXXXXXXXXLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKIIYSTDNANLDILAQAKIKRY-FLTRGEIYFDKCSDLFIIKPISFTTEASYITLAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLN-QFDFYAFEIRESFLHFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHTNSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNGD--QFDLALKAESENITGIVSGC--SGDVTDKGLCANRPCMDGRCIIGYNRFICDCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTRPNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDGNWHTLKLKRRQLSVILIIDDMEKKYNFS-GSSKLLSNDIIAVGKYETDKFSRYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPSVNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGYXXXXXXXXXXXXKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPIGERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCISSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVS-CRPNICHSGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTKNTTLDELAFGXXXXXXXXXXXXXXEGDGKQSDFISARLMKDKGRALLIIEYNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG-KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIPLSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQS----ILSEQGXXXXXXXXXXXXIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSY----------KINTVTHSQKITTTPDNDIYTENTKSESSTIYKSLEINNSGV--------INIWLIIGFSVGGSLLLVFITCFIYRCFRKDEGSYNVEDDHIFIDPSHXXXXXXXXXXDIELKNNYQTLNSATFNSSKHKQSRNEKSTNTKEWYV 3981
            +IN +FKTKQD S +FY+G+ P  ++    +  Q+I +Y++D    I I + +  +S+F   K  C SIY TC D++WH + +            +    +V+           L+   L +++I            +  Q        L+ F+GCM++I    +N  L+I+     K Y F + G++  D C ++F IKP+SFT  + Y+   G    +K K   SFKT +S+ L+AYQ S    ++   DFY+ EIR+  L+FSI   S VY + +S+  VS+GL H + L FE   + + LD +  + + ++ Y  ++    LYIG + +T +  + H +WSGIL   F GC+  ++++    Q DL +K  S     I SGC  S ++    +CAN+PC +G C I +++  CDC++TN+TG+TC + A + +FNG+Q M I  PN ++SE E+  L F +  PNG+ + T+++ SG +D+LEIF++NG + ILLNFGRGNK  ++  NCFD  WH++K+KRR+ ++ + IDD   ++N    SSKL+SNDII +GK +  + +++F GYMMHF +NG NYFELAK+ SP NIE+TA++  A   ++F I+F S  SY+ +PK++++GDF+LEF +KT    G +L L G+S DYLILE+V+G L++++NWG+G+ +K+ +   ++D +WH V ++R  SK+ SFAFR+D +P   RA + +  GGLNFN F  + LG   +  S      +   S  GF+GCI+SFY+N +    T  +Y++LL  A   + V E+CP++HN + + C  + C  GG+C Q W++  CDC+ T+F G +C+ VS T +F  +P+YL+YK S  K  ++++LAFG QT+    + +I I G    S  ++  +        + +EY   +G    +ES +N+ DG YH V FR++   A+L++DD +  I  P G   +   +++  + VG     ++            +SF G++SGL  N I + D +     + I L+N+SNV      +PNFQ ++S      SE+  K     +KNN IVVA+  C  I       C+     GI++P V++          K N    + + T  P   +   N ++ S     +++IN            INIWLI  FS GG+ +L+ ++C IYRC  KDEGSYNV++D I I  ++ + + L S  + + K+N Q+L +   N  K K+ R   S  TKEWYV
Sbjct:  274 SINFQFKTKQDNSFLFYIGSLPGLAEQFQISKTQFISVYIEDGLFHIIISNPQSVDSSFYTRKFHCNSIYKTCADDKWHNVQIK-----------EFRNDIVITLDDFQKEFKNLSNQQL-TKTIHMKFAKATEPFQYYRQTQLPQYPPLSQFRGCMKEIYLHQNNVTLNIVEMVTKKVYNFHSNGKLNSDICMEMFPIKPVSFTRNSDYLQAFGIRSVRKAKFSLSFKTHKSDCLIAYQPSSKKGIHTDTDFYSIEIRDFALYFSIGLNSVVYSKVMSNYNVSNGLLHNIVLHFELPVIRIILDKENYVLNISTNYHDIEFEGSLYIGSLDDTKILSVSHHVWSGILGTYFSGCIFSLTIDDSPIQLDLLIKKNS----SISSGCKTSEEMHSLNVCANQPCNEGICQIEWDQRSCDCTKTNFTGNTCNKEAIIAEFNGYQFMRIKFPNTYKSEVENFYLMFKSKLPNGLILSTQNQFSGTTDKLEIFMQNGSIYILLNFGRGNKKFKTLENCFDDKWHSIKMKRRRKNLKVWIDDNYYEFNIQDSSSKLVSNDIIHLGKVKRME-NQFFMGYMMHFIYNGRNYFELAKKLSPLNIELTASLQPANVMRQFAINFHSTKSYLVIPKVNIFGDFRLEFQMKTLQPSGLLLFLQGESNDYLILEMVNGLLHIIYNWGSGYKRKISESGLLNDGLWHSVKIVRHMSKTHSFAFRVDGKPDDSRADVPVNTGGLNFNHFGKMHLGGYLENQSIVTFDNETPRSKGGFQGCIASFYVNNSISTDTVILYKDLLKEANEKHYVDENCPDNHNDKENYCSIDSCSFGGKCTQHWMKYSCDCSSTSFSGPKCEDVSTTAQFVKHPSYLVYKYSIIKKHSINQLAFGFQTNTRKFAPLISIIGTQSLSPLLTIEIKIVNDYGFIQVEYYTNTGTHSFMESRLNVIDGLYHIVRFRKDRMAATLKLDDLSDRIHVPDGIDQNTVVDEELMVIVGSSEVSSK------------NSFQGFISGLTINEIAILDTLKENFNSYILLINKSNV----DLVPNFQPRRSDQSLKQSEEEPKNPETNQKNNRIVVARPQCPGITEAEKFQCQQYHYKGIVKPGVAFKKPNTQEKHSKTNFEEFASRSTNKPFEYLLPNNDQTTSDFNINNMKINPKNENTIKSNLNINIWLIAAFSCGGTFMLIALSCLIYRCSTKDEGSYNVKEDRICIQ-TNLNSSKLKSKLNCDEKSN-QSLLTKIPNKRKSKRKR---SGETKEWYV 1502

The following BLAST results are available for this feature:

BLAST of neurexin-1 isoform X19 vs. Ensembl Human
BLAST of neurexin-1 isoform X19 vs. Ensembl Celegans
BLAST of neurexin-1 isoform X19 vs. Ensembl Fly
BLAST of neurexin-1 isoform X19 vs. Ensembl Zebrafish
BLAST of neurexin-1 isoform X19 vs. Ensembl Xenopus
BLAST of neurexin-1 isoform X19 vs. Ensembl Mouse
BLAST of neurexin-1 isoform X19 vs. UniProt/SwissProt
BLAST of neurexin-1 isoform X19 vs. TrEMBL
BLAST of neurexin-1 isoform X19 vs. Ensembl Cavefish
BLAST of neurexin-1 isoform X19 vs. Ensembl Sea Lamprey
BLAST of neurexin-1 isoform X19 vs. Ensembl Yeast
BLAST of neurexin-1 isoform X19 vs. Ensembl Nematostella
BLAST of neurexin-1 isoform X19 vs. Ensembl Medaka
BLAST of neurexin-1 isoform X19 vs. Planmine SMEST

BLAST of neurexin-1 isoform X19 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NRXN1	1.447e-104	25.65	neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008]	[more]
NRXN1	2.073e-101	25.52	neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008]	[more]
NRXN3	1.926e-100	26.91	neurexin 3 [Source:HGNC Symbol;Acc:HGNC:8010]	[more]
NRXN1	3.631e-100	25.28	neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008]	[more]
NRXN1	4.084e-100	25.14	neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008]	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nrx-1	7.297e-74	25.67	NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2H...	[more]
nrx-1	1.738e-73	25.67	NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2H...	[more]
nrx-1	2.488e-73	25.44	NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2H...	[more]
nrx-1	3.142e-73	25.44	NeuReXin related [Source:UniProtKB/TrEMBL;Acc:I2H...	[more]
unc-52	3.008e-9	28.19	Basement membrane proteoglycan [Source:UniProtKB/...	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nrx-1	1.389e-85	25.43	gene:FBgn0038975 transcript:FBtr0334611	[more]
Nrx-1	1.919e-85	25.59	gene:FBgn0038975 transcript:FBtr0334609	[more]
Nrx-1	2.656e-85	25.59	gene:FBgn0038975 transcript:FBtr0334610	[more]
Nrx-1	2.684e-85	25.52	gene:FBgn0038975 transcript:FBtr0334612	[more]
Nrx-1	2.684e-85	25.52	gene:FBgn0038975 transcript:FBtr0334608	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nrxn1a	4.469e-108	25.67	neurexin 1a [Source:NCBI gene;Acc:565531]	[more]
nrxn1a	1.012e-104	25.41	neurexin 1a [Source:NCBI gene;Acc:565531]	[more]
nrxn1a	1.142e-104	25.41	neurexin 1a [Source:NCBI gene;Acc:565531]	[more]
nrxn1a	3.230e-104	25.35	neurexin 1a [Source:NCBI gene;Acc:565531]	[more]
nrxn1a	3.897e-104	25.14	neurexin 1a [Source:NCBI gene;Acc:565531]	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NRXN3	1.663e-101	27.84	neurexin 3 [Source:NCBI gene;Acc:100379902]	[more]
NRXN3	2.314e-99	27.32	neurexin 3 [Source:NCBI gene;Acc:100379902]	[more]
NRXN3	3.173e-98	26.87	neurexin 3 [Source:NCBI gene;Acc:100379902]	[more]
NRXN3	3.345e-98	27.50	neurexin 3 [Source:NCBI gene;Acc:100379902]	[more]
NRXN3	3.376e-98	27.50	neurexin 3 [Source:NCBI gene;Acc:100379902]	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nrxn1	9.037e-105	27.25	neurexin I [Source:MGI Symbol;Acc:MGI:1096391]	[more]
Nrxn1	1.976e-101	27.06	neurexin I [Source:MGI Symbol;Acc:MGI:1096391]	[more]
Nrxn1	2.422e-100	26.71	neurexin I [Source:MGI Symbol;Acc:MGI:1096391]	[more]
Nrxn1	4.354e-100	26.78	neurexin I [Source:MGI Symbol;Acc:MGI:1096391]	[more]
Nrxn1	4.790e-100	26.78	neurexin I [Source:MGI Symbol;Acc:MGI:1096391]	[more]

BLAST of neurexin-1 isoform X19 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9ULB1\|NRX1A_HUMAN	6.949e-104	25.65	Neurexin-1 OS=Homo sapiens OX=9606 GN=NRXN1 PE=1 S...	[more]
sp\|A1XQX0\|NR1AA_DANRE	3.017e-102	25.06	Neurexin-1a OS=Danio rerio OX=7955 GN=nrxn1a PE=2 ...	[more]
sp\|Q28146\|NRX1A_BOVIN	1.836e-100	25.12	Neurexin-1 OS=Bos taurus OX=9913 GN=NRXN1 PE=1 SV=...	[more]
sp\|Q9CS84\|NRX1A_MOUSE	1.694e-99	26.71	Neurexin-1 OS=Mus musculus OX=10090 GN=Nrxn1 PE=1 ...	[more]
sp\|A1XQY1\|NR3BA_DANRE	3.590e-99	26.40	Neurexin-3b OS=Danio rerio OX=7955 GN=nrxn3b PE=2 ...	[more]

BLAST of neurexin-1 isoform X19 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A210PI37	5.447e-114	30.04	Neurexin-1a OS=Mizuhopecten yessoensis OX=6573 GN=...	[more]
A0A4E0S3K8	2.401e-112	27.24	Neurexin OS=Fasciola hepatica OX=6192 GN=D915_0000...	[more]
A0A430QHY5	4.979e-112	27.40	Neurexin OS=Schistosoma bovis OX=6184 GN=DC041_001...	[more]
A0A4Z2DG09	1.617e-111	28.19	Neurexin-1 (Fragment) OS=Schistosoma japonicum OX=...	[more]
A0A3P8G6Q0	1.060e-110	27.64	Uncharacterized protein OS=Schistosoma margrebowie...	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000011949.2	3.213e-101	25.77	pep primary_assembly:Astyanax_mexicanus-2.0:6:2098...	[more]
ENSAMXT00000000309.2	1.760e-99	25.08	pep primary_assembly:Astyanax_mexicanus-2.0:21:105...	[more]
nrxn3a	3.171e-98	27.16	neurexin 3 [Source:NCBI gene;Acc:103035103]	[more]
nrxn3a	3.010e-97	26.86	neurexin 3 [Source:NCBI gene;Acc:103035103]	[more]
ENSAMXT00000043111.1	2.268e-96	28.03	pep primary_assembly:Astyanax_mexicanus-2.0:14:799...	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000002142.1	2.328e-94	26.52	pep scaffold:Pmarinus_7.0:GL476386:209124:506099:1...	[more]
ENSPMAT00000004299.1	2.175e-30	26.27	pep scaffold:Pmarinus_7.0:GL477235:143017:163597:1...	[more]
cntnap2b	1.976e-13	25.06	contactin associated protein like 2b [Source:ZFIN;...	[more]
ENSPMAT00000000342.1	6.981e-12	26.74	pep scaffold:Pmarinus_7.0:GL477011:22393:100421:-1...	[more]
ENSPMAT00000007718.1	3.628e-11	27.02	pep scaffold:Pmarinus_7.0:GL476589:4931:52526:1 ge...	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of neurexin-1 isoform X19 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47422	7.879e-20	24.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46873	3.258e-16	25.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36419	1.985e-15	30.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36109	5.731e-14	25.12	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39258	2.898e-13	23.99	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of neurexin-1 isoform X19 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000034989.1	8.353e-102	25.66	neurexin 1 [Source:NCBI gene;Acc:101159771]	[more]
ENSORLT00000046931.1	1.033e-101	25.66	neurexin 1 [Source:NCBI gene;Acc:101159771]	[more]
ENSORLT00000030454.1	1.700e-101	25.43	neurexin 1 [Source:NCBI gene;Acc:101159771]	[more]
ENSORLT00000033187.1	1.700e-101	25.43	neurexin 1 [Source:NCBI gene;Acc:101159771]	[more]
ENSORLT00000027034.1	1.951e-101	25.66	neurexin 1 [Source:NCBI gene;Acc:101159771]	[more]

BLAST of neurexin-1 isoform X19 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000058569.1	0.000e+0	99.84	SMESG000058569.1	[more]
SMESG000058569.1	0.000e+0	99.14	SMESG000058569.1	[more]
SMESG000058569.1	0.000e+0	98.89	SMESG000058569.1	[more]
SMESG000058569.1	0.000e+0	98.89	SMESG000058569.1	[more]
SMESG000066308.1	0.000e+0	35.67	SMESG000066308.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016804 ID=SMED30016804|Name=neurexin-1 isoform X19|organism=Schmidtea mediterranea sexual|type=transcript|length=4108bp
AAGGATTTTTAAAATAATTTTACTAAGAAGAATAAAAAGGTCAATCGGTT
TTCCAGAAATTATAAATGAAAAATTATCTTTTCTTGACAAATCATTAAAC
TCTTTTGAAAAGTGATTCTTTGATGATCATTATAATTCATTAAATGTTAT
TATAAAATGGAAACTATTAATTTCTTTTTGATCTCTTTTGTTATAATTCA
CACAGGAACTACCGAAGAAATACCTGTAGCAACATTCCTCCAAGATGCAT
ATATTTACAATTCAATTAATATTCCTACTGTCAGTGACATGGATGCGATT
AATTTAGAATTCAAAACCAAACAAGATTTCTCCCATATTTTTTATGTTGG
AACGCAGCCATCACATTCAAAGACTGGGTTGCAGTACATACTGATGTATC
TGGATGACAGACAATTGGGCATTAGAATCAAGCACGACAGACTCCCAGAG
TCCACATTCAAAGTCACTTGTGTCAGCATCTATTCAACCTGTACCGACAA
TCGTTGGCATACAATCTCGGTATCCCGGAAAAAAACCTCTGAGAAAAATT
CTTCTGGACAGTTAGTTATCAAAGTCGTCGTTGATGGAAAAGTCGTCGTG
GATAGGATGGTGGGGCTGACAGTCACCCATCTCATCAGTCAATCTATCAC
ATTTGGTGGAATGATTCCAATGACTGATTCTGATTTCAGTATCCAGGAAA
CTGCATCTTTTCTACAAAACTTGACAAACTTTAAGGGATGCATGCAAAAA
ATAATATACTCAACTGATAATGCCAATTTGGATATACTTGCTCAAGCAAA
AATAAAAAGATATTTTCTAACTCGTGGAGAAATATATTTTGATAAATGTT
CAGATCTCTTCATTATTAAACCTATATCATTTACTACTGAAGCGTCTTAC
ATAACTCTAGCAGGATGGGCATGGGCTCAAAAGGGTAAACTTCAATTTTC
CTTTAAAACTGTCGAATCAAACGCTTTGCTTGCATATCAAAAGTCAGAAA
CATCTCAATTGAATCAATTTGATTTCTATGCTTTTGAAATTAGAGAGTCT
TTCCTTCATTTTTCAATAAACACTGGATCTGGAGTTTACCAACAAAAAGT
GTCTTCTACACCTGTATCAGATGGTCTAAGTCATTATGTAAAACTTTGGT
TTGAAGATGGCAATGTCGAAGTTCAACTCGATGCCGATAAAAAAATAGAG
CACACTAATAGCTTATATAAAACACTTGACACTACAAGAGATCTTTATAT
TGGAGGAATCCCTGAAACCCTTGTGTCGTTTCTTCCTCATTCTCTGTGGT
CAGGAATTTTGCGACAAGGATTTGTTGGATGTTTATTAGATATCAGCGTA
AATGGTGATCAGTTCGATTTAGCATTGAAGGCTGAAAGTGAAAATATAAC
TGGAATTGTTAGTGGATGTTCTGGTGATGTGACTGACAAAGGTCTTTGTG
CAAACAGACCGTGCATGGATGGAAGATGTATTATTGGATATAACAGATTC
ATTTGCGATTGTTCAAGGACAAATTACACTGGCGATACATGCGGGAGAGT
GGCTCCATTGGTGAAATTCAATGGATTTCAACAAATGATAATAAATATGC
CCAACGGATTTCAATCGGAATGTGAGGACGTTACGCTAAGATTTCTAACC
ACGCGTCCCAATGGCATATTTATTGTAACTAAAAGTCGAGTTTCCGGAGC
TTCTGATAGACTTGAGATATTTCTCGAAAACGGAAAATTAAATATTTTGC
TCAATTTCGGCCGTGGAAATAAAATTATTCGATCAGATTATAATTGTTTC
GACGGGAATTGGCATACTCTAAAACTGAAGAGGCGTCAATTGTCAGTTAT
TCTCATCATTGATGACATGGAAAAGAAATATAATTTTAGTGGATCTAGCA
AATTGCTATCGAACGATATCATTGCAGTGGGTAAATATGAAACTGATAAA
TTCAGTCGGTATTTCACTGGATATATGATGCATTTTACATTTAATGGAAT
AAATTATTTTGAACTCGCAAAAGAAGAATCACCTTCAAATATCGAAGTCA
CCGCCACAATTGGTGATGCTGAACCGACGAAAGAATTCCCAATCTCTTTT
CCCTCGGTCAACTCTTATATCCGACTGCCGAAAATCGATATGTATGGAGA
TTTTAAATTAGAATTCTTAATTAAAACAAGAAATAATAAAGGATCAGTTC
TTCAATTGTACGGGAAAAGTGGTGACTATTTAATTTTAGAAATAGTTCAC
GGTTACTTGAACCTGTTATTTAATTGGGGGAATGGATTCAATAAAAAGGT
CAGAAAAGAGATCAAAATTGACGACAACATATGGCACAGAGTAATACTGA
TCAGGGAGAATTCAAAATCAAGTTCATTTGCTTTTCGAATTGACAGTCAA
CCTATAGGTGAAAGAGCTCATATTGAATTGAAAGCTGGAGGGTTAAACTT
CAATTCTTTTGAAAATCTCTTTCTTGGAAGTGCAGAGAAATATTTATCTA
AAACCAATCAAATCAGAGATAAAGTAACATCAAGTCAAGGGTTTGAAGGT
TGTATATCTTCATTTTATATGAATCAGACAAAATACGTTTCAACAAAATC
AGTGTATCAAAACCTTTTAGCTATAGCCTTAGCGAATAACGGAGTTGTAG
AAGATTGTCCTGAAGACCACAATTATCAAGTGAGCTGTCGACCTAATATT
TGTCATTCCGGAGGTAGATGTATACAGCAATGGATACGAATTAGATGTGA
CTGTGCAATGACTACATTTATCGGCGAAAGATGTGATAAAGTTAGTAAAA
CACTGAAGTTCAACGATTATCCGGCCTATTTGATTTACAAATTGTCTCCG
ACAAAAAATACAACTCTGGACGAGCTGGCATTTGGTATACAAACATCAGT
AATCACGTCTTCATCCATCATTCTGATAGAAGGCGATGGAAAGCAATCGG
ATTTCATATCAGCCAGATTAATGAAGGATAAGGGTAGGGCACTGTTGATA
ATTGAGTACAATCTGGGGAGTGGGATCACGAGGCTGGTCGAGTCTTCTGT
GAACATCGCTGATGGGTTTTATCATAGGGTAGCGTTTAGGAGAAACGGAA
ATCTCGCTTCTTTACAAATTGATGATTACAATAGGATAATCGCATCACCT
AAAGGTAAAACAAGTATACATTTCAATCAACAGCGCACGATTTATGTCGG
TAAGTATCCATTTCCAAACCAGAGAACAGGACGATCAGTGCAGAATGACA
AAACGTTTGATTCTTTCAGCGGTTATTTGTCAGGCCTATATTTTAATCGG
ATTCCCCTGAGCGATATGATCGACAATATCAGCTATGCTGGGATTAAATT
GTTGAACCGATCAAATGTTTATGTTGAAAACAAATTTATCCCGAATTTCC
AATCCAAACAATCTATATTATCAGAACAAGGAGAAAAAGAAAATAATCCA
ACAAAAAAAAACAATCCAATTGTGGTAGCCAAGTCGAATTGTTCAAACAT
AGAACCTTTGCATAATTTAGATTGTAAAGTGTCGGATTCAGCTGGCATAA
TACGACCCATTGTATCTTATAAAATAAATACTGTCACCCATTCACAGAAA
ATAACAACAACCCCAGACAACGACATTTACACTGAAAACACGAAATCAGA
ATCCAGTACGATATACAAATCGCTGGAAATAAACAATTCAGGAGTCATAA
ATATTTGGTTAATAATCGGATTCTCAGTTGGCGGAAGTCTTTTGTTGGTG
TTTATCACTTGTTTCATATACAGATGTTTCCGAAAAGACGAAGGTTCGTA
CAATGTCGAAGATGATCATATCTTTATAGATCCCTCTCATAAATCACTAA
ATCTTTTAAATTCCTCAAAAGACATTGAATTGAAAAACAATTATCAAACA
TTGAATAGTGCAACTTTTAATTCTTCAAAACATAAACAATCGAGGAATGA
AAAATCAACAAACACCAAAGAATGGTACGTGTGACATCCGGTCGGGTCAC
CTGAGGAATTATGTGCATTTATCTAATATATATATTTATAATTAACCTCT
TTTTTAAAGAGTTCCTTGTATATAGAATGTGATCAAGTTTTTTACATTTG
TTAATAAT

protein sequence of SMED30016804-orf-1

>SMED30016804-orf-1 ID=SMED30016804-orf-1|Name=SMED30016804-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1276bp
METINFFLISFVIIHTGTTEEIPVATFLQDAYIYNSINIPTVSDMDAINL
EFKTKQDFSHIFYVGTQPSHSKTGLQYILMYLDDRQLGIRIKHDRLPEST
FKVTCVSIYSTCTDNRWHTISVSRKKTSEKNSSGQLVIKVVVDGKVVVDR
MVGLTVTHLISQSITFGGMIPMTDSDFSIQETASFLQNLTNFKGCMQKII
YSTDNANLDILAQAKIKRYFLTRGEIYFDKCSDLFIIKPISFTTEASYIT
LAGWAWAQKGKLQFSFKTVESNALLAYQKSETSQLNQFDFYAFEIRESFL
HFSINTGSGVYQQKVSSTPVSDGLSHYVKLWFEDGNVEVQLDADKKIEHT
NSLYKTLDTTRDLYIGGIPETLVSFLPHSLWSGILRQGFVGCLLDISVNG
DQFDLALKAESENITGIVSGCSGDVTDKGLCANRPCMDGRCIIGYNRFIC
DCSRTNYTGDTCGRVAPLVKFNGFQQMIINMPNGFQSECEDVTLRFLTTR
PNGIFIVTKSRVSGASDRLEIFLENGKLNILLNFGRGNKIIRSDYNCFDG
NWHTLKLKRRQLSVILIIDDMEKKYNFSGSSKLLSNDIIAVGKYETDKFS
RYFTGYMMHFTFNGINYFELAKEESPSNIEVTATIGDAEPTKEFPISFPS
VNSYIRLPKIDMYGDFKLEFLIKTRNNKGSVLQLYGKSGDYLILEIVHGY
LNLLFNWGNGFNKKVRKEIKIDDNIWHRVILIRENSKSSSFAFRIDSQPI
GERAHIELKAGGLNFNSFENLFLGSAEKYLSKTNQIRDKVTSSQGFEGCI
SSFYMNQTKYVSTKSVYQNLLAIALANNGVVEDCPEDHNYQVSCRPNICH
SGGRCIQQWIRIRCDCAMTTFIGERCDKVSKTLKFNDYPAYLIYKLSPTK
NTTLDELAFGIQTSVITSSSIILIEGDGKQSDFISARLMKDKGRALLIIE
YNLGSGITRLVESSVNIADGFYHRVAFRRNGNLASLQIDDYNRIIASPKG
KTSIHFNQQRTIYVGKYPFPNQRTGRSVQNDKTFDSFSGYLSGLYFNRIP
LSDMIDNISYAGIKLLNRSNVYVENKFIPNFQSKQSILSEQGEKENNPTK
KNNPIVVAKSNCSNIEPLHNLDCKVSDSAGIIRPIVSYKINTVTHSQKIT
TTPDNDIYTENTKSESSTIYKSLEINNSGVINIWLIIGFSVGGSLLLVFI
TCFIYRCFRKDEGSYNVEDDHIFIDPSHKSLNLLNSSKDIELKNNYQTLN
SATFNSSKHKQSRNEKSTNTKEWYV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0000240	body wall musculature
PLANA:0000418	head
PLANA:0003001	lateral region of the whole animal

Vocabulary: **INTERPRO**
Term	Definition
IPR000742	EGF-like_dom
IPR001791	Laminin_G
IPR013320	ConA-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005509	calcium ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001791	Laminin G domain	SMART	SM00282	LamG_3	coord: 423..550 e-value: 1.0E-13 score: 61.5 coord: 599..743 e-value: 3.6E-14 score: 63.1 coord: 838..984 e-value: 1.2E-13 score: 61.3 coord: 193..336 e-value: 9.8E-25 score: 98.2 coord: 2..139 e-value: 0.94 score: 2.4
IPR001791	Laminin G domain	PFAM	PF02210	Laminin_G_2	coord: 11..136 e-value: 1.4E-7 score: 32.1 coord: 201..335 e-value: 6.3E-19 score: 68.8 coord: 431..549 e-value: 1.5E-12 score: 48.2 coord: 607..742 e-value: 2.7E-16 score: 60.3 coord: 855..983 e-value: 6.2E-14 score: 52.7
IPR001791	Laminin G domain	PROSITE	PS50025	LAM_G_DOMAIN	coord: 816..1010 score: 22.169
IPR001791	Laminin G domain	PROSITE	PS50025	LAM_G_DOMAIN	coord: 579..769 score: 28.467
IPR001791	Laminin G domain	PROSITE	PS50025	LAM_G_DOMAIN	coord: 173..356 score: 34.41
IPR001791	Laminin G domain	PROSITE	PS50025	LAM_G_DOMAIN	coord: 403..573 score: 18.143
IPR001791	Laminin G domain	PROSITE	PS50025	LAM_G_DOMAIN	coord: 1..166 score: 18.828
IPR000742	EGF-like domain	SMART	SM00181	egf_5	coord: 365..398 e-value: 4.2 score: 16.3 coord: 778..812 e-value: 14.0 score: 14.3
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 362..398 score: 9.841
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 775..812 score: 12.155
None	No IPR available	GENE3D	G3DSA:2.60.120.200		coord: 577..754 e-value: 1.3E-25 score: 92.1
None	No IPR available	GENE3D	G3DSA:2.60.120.200		coord: 4..155 e-value: 6.2E-11 score: 44.1
None	No IPR available	GENE3D	G3DSA:2.60.120.200		coord: 400..574 e-value: 7.0E-26 score: 92.9
None	No IPR available	GENE3D	G3DSA:2.10.25.10		coord: 363..399 e-value: 3.5E-8 score: 35.1 coord: 776..811 e-value: 1.0E-11 score: 46.5
None	No IPR available	GENE3D	G3DSA:2.60.120.200		coord: 171..356 e-value: 2.0E-41 score: 143.7
None	No IPR available	GENE3D	G3DSA:2.60.120.200		coord: 812..998 e-value: 4.5E-30 score: 106.8
None	No IPR available	PANTHER	PTHR15036	FAMILY NOT NAMED	coord: 41..989
None	No IPR available	PANTHER	PTHR15036:SF51	NEUREXIN-1	coord: 41..989
None	No IPR available	CDD	cd00110	LamG	coord: 824..982 e-value: 2.3306E-18 score: 81.3104
None	No IPR available	CDD	cd00110	LamG	coord: 425..542 e-value: 3.92868E-14 score: 68.984
None	No IPR available	CDD	cd00110	LamG	coord: 174..334 e-value: 2.14877E-23 score: 95.5628
None	No IPR available	CDD	cd00110	LamG	coord: 580..741 e-value: 1.27051E-19 score: 84.7772
None	No IPR available	TMHMM	TMhelix		coord: 1118..1140
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	SUPERFAMILY	SSF49899	Concanavalin A-like lectins/glucanases	coord: 579..770
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	SUPERFAMILY	SSF49899	Concanavalin A-like lectins/glucanases	coord: 166..356
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	SUPERFAMILY	SSF49899	Concanavalin A-like lectins/glucanases	coord: 384..552
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	SUPERFAMILY	SSF49899	Concanavalin A-like lectins/glucanases	coord: 798..987
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	SUPERFAMILY	SSF49899	Concanavalin A-like lectins/glucanases	coord: 7..167

Main menu

neurexin-1 isoform X19

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Owlery

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