SMED30016784

Query:  458 NEIPYRINEIVKISE-TKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRK-RMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNC-------------------LSKDDNNQNDMLL-ACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTT-------SQTRSGQPNTD 1201
            N +   +N++  I   T    N  DS    LC + VLLVCM++ +G T TGLG+FL      ++ K+CA+ +G PL+ SG    FI  +R++      ++  ++ +  G++SF C I+CL++S+++G  G+ I+ + + C                   ++ + +N N   +  CCY+I        + +TC C        S       Y NL+CR +FS++KDY+ILQ ALMGVGSGV LW   + I+  ++    +       S TRS  P T 
Sbjct:  549 NSVDLELNKLDTIQNITDLHTNKGDSFTRCLCSLIVLLVCMQLAVGITSTGLGLFLTWKVPELEPKECAYLSGIPLIISGFIGTFIC-FRHRFPSISPELMNIIQLTSGILSFGCFIICLITSVYAGQKGSEIASYENTCRIVTIKQNEQQSTNKVLYPVTMNYSNTNHYFIEPCCYEI--------VKNTCECFTITGQRIS------CYHNLSCRLLFSSIKDYIILQSALMGVGSGVSLWSWLLVIENKLKYLLNSKYVRMSFSSTRSSVPETS 810          

Query:  545 LCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNCLSKD-------------------DNNQNDMLLA----CCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWL 1123
             C++ VLLV M+I LG   TGLG++L      + +++C+FWA  P+  +GLF  +    R   RK  +I   +    G +S I  ILCL++SIFSG  G+ I+ +  +C+  +                      + D  L     CC D    G++      C C   R  +        +Y  + CRY+FS++KDYLILQ ALM VG+GVCLW 
Sbjct:  537 FCQLIVLLVSMQISLGLAATGLGLYLRWRVPLLPLEECSFWAALPITITGLFGTYFCFQRRISRKNPQITLAIRRIAGALSLISCILCLVASIFSGQKGSLIATYGTDCIPSNPLYSIHNSSIKNNDNSNNNQEKKTDYDLGFEQQCCID----GVDRMSEPLCQCFNVRNQLM------WSYRGIACRYLFSSVKDYLILQSALMAVGTGVCLWF 742          

Query:  518 NSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNCLSKDD-------------------NNQNDMLLA----CCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWL 1123
            N R S     C++ VLLV M+I LG   TGLG++L      + +++C+FWA  P+  +G    +    R   RK  +I   +    GV+S I  ILCL++SIFSG  G+ I+ +  +C+  +                      + D  L     CC D    G++      C C   R  +        +Y  + CRY+FS++KDYLILQ ALM VG+GVCLW 
Sbjct:  529 NRRSSRGLCFCQLIVLLVSMQISLGLAATGLGLYLRWRVPLLPLEECSFWAALPISITGFIGTYFCFQRRISRKNPQITLAIRRIAGVLSLISCILCLVASIFSGQKGSLIATYGTDCIPSNPLYSVHNSSIKNNNNSNNSLERKPDYDLGFEQQCCID----GVDRMSEPLCQCFNVRNQLM------WSYRGIACRYLFSSVKDYLILQSALMAVGTGVCLWF 743          

Query:  545 LCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLF-EVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNCLS------KDDNNQNDMLL----ACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWL-LQMTIQRLI 1150
             C++ VLLV M+I+LG + T LG +L      + +++CAFWA  PL F+G+   +F +  R + R        M  A G++S I  +LCL++SIFSG  GN I+     C S        +  Q+  L      CC D  T G++   ++ C C   R  +        +Y  + CRY+ S++KDYLILQ ALM V +GVCLW  + +T QR +
Sbjct:  470 FCQLHVLLVIMQIVLGVSTTALGFYLHWKIPLLPLEECAFWAAIPLSFTGMIGSLFCFENRCQ-RFNRSYSVSMRRATGILSLISCVLCLVASIFSGQKGNVIATSGHPCQSIRLTTQTKNATQSSGLPEYEHQCCSD--TSGLDG--HNVCQCLNMRNQV------IWSYHKITCRYLISSVKDYLILQSALMAVAAGVCLWFWVVLTEQRYV 672          

Query:  545 LCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLF-EVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWI--SGHSDNCLSKDDNNQN--------DMLLACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWL-LQMTIQRLI 1150
             C++ VLLV M+I+LG + T LG +L      + +++CAFWA  PL F+G+   +F +  R +L  R      M  A G+++ I  +LCL++SIFSG  GN I  SGH    +      +N        +    CC D  T  ++   ++ C C   R  +        +Y  + CRY+ S++KDYLILQ ALM V +GVCLW  + +T QR +
Sbjct:  470 FCQLHVLLVIMQIVLGMSTTALGFYLHWKIPLLPLEECAFWAAIPLSFTGIIGSLFCFENRCQLFNR-SYSVSMRRATGILTLISCVLCLVASIFSGQKGNVIASSGHPCQIVRPTTQTKNATQSSGLPEYEHQCCSD--TSSLDG--HNVCQCLNMRNQV------IWSYHKITCRYLISSVKDYLILQSALMAVAAGVCLWFWVVLTEQRYV 672          

Query:   17 MMYNQSSDKVEWGHMKMPEIIIDSDNESTTKNYDNESYNNCFLKANREESNHLTCKSNLDDADSGIHESNDIFLPGISSVLHPNRLSLRDMKKRSNLSEVRSYSTNCLSVDTNRYKEGLGMIDPRLCRNCSTKSHSKKQFDSIKREPNEIPYRINEIVKISETKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNCLSKDDNNQNDMLLACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTTSQTRSGQPNTDDQNSVGQSPVIPLKIRCIQVNEKSQILNDYIREKSXXXXXXXXXRFHSELYKPNPE 1369
            MMYNQSSDKVEWGHMKMPEIIIDSDNESTTKNYDNESYNNCFLKANREESNHLTCKSNLDDADSGIHESNDIFLPGISSVLHPNRLSLRDMKKRSNLSEVRSYSTNCLSVDTNRYKEGLGMIDPRLCRNCSTKSHSKKQFDSIKREPNEIPYRINEIVKISETKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVISFICSILCLLSSIFSGVHGNWISGHSDNCLSKDDNNQNDMLLACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTTSQTRSGQPNTDDQNSVGQSPVIPLKIRCIQVNEKSQILNDYIREKSNNFNYINNNRFHSELYKPNPE
Sbjct:    1 MMYNQSSDKVEWGHMKMPEIIIDSDNESTTKNYDNESYNNCFLKANREESNHLTCKSNLDDADSGIHESNDIFLPGISSVLHPNRLSLRDMKKRSNLSEVRSYSTNCLSVDTNRYKEGLGMIDPRLCRNCSTKSHSKKQFDSIKREPNEIPYRINEIVKISETKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVISFICSILCLLSSIFSGVHGNWISGHSDNCLSKDDNNQNDMLLACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTTSQTRSGQPNTDDQNSVGQSPVIPLKIRCIQVNEKSQILNDYIREKSNNFNYINNNRFHSELYKPNPE 451          

Query:   20 MYNQSSDKVEWGHMKMPEIIIDSDNESTTKNYDNESYNNCFLKANREESNHLTCKSNLDDADSGIHESNDIFLPGISSVLHPNRLSLRDMKKRSNLSEVRSYSTNCLSVDTNRYKEGLGMIDPRLCRNCSTKSHSKKQFDSIKREPNEIPYRINEIVKISETKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNCLSKDDNNQNDMLLACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTTSQTRSGQPNTDDQNSVGQSPVIPLKIRCIQVNEKSQILNDYIREKSXXXXXXXXXRFHSELYKPNPE 1369
            MYNQSSDKVEWGHMKMPEIIIDSDNESTTKNYDNESYNNCFLKANREESNHLTCKSNLDDADSGIHESNDIFLPGISSVLHPNRLSLRDMKKRSNLSEVRSYSTNCLSVDTNRYKEGLGMIDPRLCRNCSTKSHSKKQFDSIKREPNEIPYRINEIVKISETKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVISFICSILCLLSSIFSGVHGNWISGHSDNCLSKDDNNQNDMLLACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTTSQTRSGQPNTDDQNSVGQSPVIPLKIRCIQVNEKSQILNDYIREKSNNFNYINNNRFHSELYKPNPE
Sbjct:    1 MYNQSSDKVEWGHMKMPEIIIDSDNESTTKNYDNESYNNCFLKANREESNHLTCKSNLDDADSGIHESNDIFLPGISSVLHPNRLSLRDMKKRSNLSEVRSYSTNCLSVDTNRYKEGLGMIDPRLCRNCSTKSHSKKQFDSIKREPNEIPYRINEIVKISETKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVISFICSILCLLSSIFSGVHGNWISGHSDNCLSKDDNNQNDMLLACCYDIHTKGINSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTTSQTRSGQPNTDDQNSVGQSPVIPLKIRCIQVNEKSQILNDYIREKSNNFNYINNNRFHSELYKPNPE 450          

Query:  524 RDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNC---LSKDDNNQNDMLLACCYDIHTKGINS----SINST-CFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQDCSTTSQTRSGQPNTDDQNSVGQ 1222
            ++  + + C+I VLL+ M++ LG +M+GLG++L   S S+  KDC +WAG PLL SG F ++     +++ KR  +  L+ I C  +S + + L L +SI SG HG WIS  S  C     ++ +  +     CC D HT  +       +N T C C+ A    +S       Y  + CRYVFSALKDY ILQ +LMGV +GVC+W++ +             Q +  QPN  DQ ++ +
Sbjct:   94 KEKFEIQFCRINVLLISMQLGLGFSMSGLGVYLRSVSPSLTWKDCTYWAGLPLLCSGAFGLYFCLSDHEIYKRSHLSRLVKIVCACMSVVTAALTLSASIMSGTHGKWISDFSSTCDLHFIREHSETDSYPDKCCEDKHTHPMPRHKLLPMNDTMCVCKTAPFGNFSLLKFEREYAAVTCRYVFSALKDYFILQSSLMGVATGVCIWIVIL-------------QIKDEQPNMIDQENISR 321          

Query:   59 MKMPEIIIDSDNESTTKNYDNESYNNCFLKANR----EESNHLTCKSNLDDADSGIHESNDIFLPG--------ISSVL--HPN-----------RLSLRDMKKRSNLSEVRSYSTNCLSVDTNRYKEGLGMIDPRLCRNCSTKSHSKKQF------DSIKREPNEIPYRINEIVK--ISETKPKINSRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNCLSKDDNNQNDML-----LACCY---------DIHTKGI------NSSINSTCFCREARENIYSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLI 1150
            M  P I+IDS++ S   + +   Y    +K +     + S  +  KSN DD DSGIH S+++F P         I + L  HP              SL + K+    S ++       S+DT R         P   +      H +  +      DS+K     I  R + + K  +  T+P   + +     LC+I++LL+ MKI+LGS++T  G+ L   SKS+++KDC +WA   L+ SGL  ++ +   N      K+ ++ T    + S   SI+CL++SI+SGVHGNWIS H++ C  K      D +     L CC+         +I   GI      N + +++C C ++      KP     Y  L+C+Y+FS+LKD+ +L C+LMGVG G  +W +   I+ + 
Sbjct:    1 MDFPVIVIDSNSNSIKDSEEGIDYLRPSVKDDYNFLVKNSLQIQSKSN-DDGDSGIHGSSEVFGPSPVPSHKMLIENDLMDHPTGTLKKTQLSLSASSLLERKRSFTRSFIKQTKNRNYSMDTGRPSSMPKRFSPY--KLMIVDEHGQPFYVQKINRDSVK----TIISRPDSLTKDNLVLTRPHDRNTEKFVSNLCQIQLLLIIMKIVLGSSITIFGLNLHGFSKSLQMKDCGYWASSILMVSGLISIY-FASENLYVLSQKMHHIYTFLVILFSGTSSIICLMASIYSGVHGNWISFHANECHLKAIMKSRDYMPMTNELNCCFNFPGKDKQKEIFNYGIIRNLIDNQTDSNSCGCFDSAL----KP--ERIYVGLSCKYLFSSLKDHFVLICSLMGVGCGCEIWFVLYLIKYVF 403          

Query:  521 SRDSLQHRLCKIRVLLVCMKILLGSTMTGLGIFLLMASKSIKVKDCAFWAGGPLLFSGLFEVFIYNWRNKLRKRMKICYLMTIACGVXXXXXXXXXXXXXXXXGVHGNWISGHSDNC------LSKDDNNQNDMLLACCYDIHTKGINSSINSTCFCREARENI-------YSKPIITMTYENLNCRYVFSALKDYLILQCALMGVGSGVCLWLLQMTIQRLIQD 1156
            S++ L+  +C+I VLLV M++ LGS+M  LG++L   S ++ +KDC +WA  PLL +G   ++  +   K+ K+  +  ++       S +CS+LC L+S FSG HGNW++ +   C       S+  +  N    +CC  +    +       C C   RE         Y+K    ++Y N+NC YVFS+LKDYLILQCAL  V +GV +WL  +   + + D
Sbjct:   95 SKEKLELHICRINVLLVMMQLGLGSSMAALGLYLHNLSPALTLKDCPYWAAFPLLLTGFLGLYFCSAEQKVFKKDLVSMIVRNTSAAFSIVCSLLCSLASGFSGHHGNWLAYYCKVCPANLHETSEKHSIHNHPTTSCCQTLQIPKL------ICECGYYREITNHSISISYNKWNPLISYHNVNCYYVFSSLKDYLILQCALYAVAAGVSIWLSVLIWSQRVHD 313