EEF1A lysine methyltransferase 1

Overview
NameEEF1A lysine methyltransferase 1
Smed IDSMED30016770
Length (bp)693
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of EEF1A lysine methyltransferase 1 (SMED30016770) t-SNE clustered cells

Violin plots show distribution of expression levels for EEF1A lysine methyltransferase 1 (SMED30016770) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of EEF1A lysine methyltransferase 1 (SMED30016770) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for EEF1A lysine methyltransferase 1 (SMED30016770) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016770

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30016770SMESG000060931.1 SmedASXL_011845SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Human
Match: EEF1AKMT1 (EEF1A lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:27351])

HSP 1 Score: 178.333 bits (451), Expect = 1.086e-55
Identity = 90/167 (53.89%), Postives = 116/167 (69.46%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ ET  +LA E I+   +  RI C+S P+++ KL EL   N    + EYD RF+ Y E FI YDYN+PL+LP  I  + FDI+I DPP+LSEECLRKTS+TVK+L+      KI+LCTG + EE A ELL VK C  F P+H R L+NEF C+VN++
Sbjct:   46 ENWQLSQFWYSQETALQLAQEAIAAVGEGGRIACVSAPSVYQKLRELCRENFSIYIFEYDKRFAMYGEEFIFYDYNNPLDLPERIAAHSFDIVIADPPYLSEECLRKTSETVKYLTRG----KILLCTGAIMEEQAAELLGVKMC-TFVPRHTRNLANEFRCYVNYD 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Human
Match: EEF1AKMT1 (EEF1A lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:27351])

HSP 1 Score: 178.333 bits (451), Expect = 1.086e-55
Identity = 90/167 (53.89%), Postives = 116/167 (69.46%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ ET  +LA E I+   +  RI C+S P+++ KL EL   N    + EYD RF+ Y E FI YDYN+PL+LP  I  + FDI+I DPP+LSEECLRKTS+TVK+L+      KI+LCTG + EE A ELL VK C  F P+H R L+NEF C+VN++
Sbjct:   46 ENWQLSQFWYSQETALQLAQEAIAAVGEGGRIACVSAPSVYQKLRELCRENFSIYIFEYDKRFAMYGEEFIFYDYNNPLDLPERIAAHSFDIVIADPPYLSEECLRKTSETVKYLTRG----KILLCTGAIMEEQAAELLGVKMC-TFVPRHTRNLANEFRCYVNYD 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Celegans
Match: M142.8 (Protein-lysine N-methyltransferase M142.8 [Source:UniProtKB/Swiss-Prot;Acc:Q5WRN3])

HSP 1 Score: 145.591 bits (366), Expect = 2.448e-43
Identity = 75/179 (41.90%), Postives = 109/179 (60.89%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSS-----RIVCISCPTLHLKLLEL------NIPSTLLEYDTRFSC-YET-FIKYDYNSPLELPADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVL 652
            EDWQLSQFWY+ ET++KL  E ++ + + S     RI C+S PTL     E        I  TL E+D RF   + T F+ YDY  P +LPA++  +FD+II DPPFL+ ECL KT+ +++ L  SD   K++LCTG + E+ A  L+ + +   F+P+H   L+N+F CF N++ L  
Sbjct:   42 EDWQLSQFWYDDETSRKLVAEGVAAALEGSEARPARIGCVSSPTLVKFFHETEEYKTGQIQLTLFEFDDRFGLKFPTEFVHYDYKHPTDLPAELLAKFDVIIADPPFLAAECLIKTAHSIRLLGKSD--VKVLLCTGAIMEDYASRLMAMHRT-SFEPRHANNLANDFSCFANYQTLTF 217
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Fly
Match: CG9154 (gene:FBgn0031777 transcript:FBtr0079213)

HSP 1 Score: 123.635 bits (309), Expect = 1.516e-34
Identity = 67/181 (37.02%), Postives = 102/181 (56.35%), Query Frame = 2 
Query:  125 NQKNTESSPSEDWQLSQFWYNSETTQKLADEVI------SQSSDSSRIVCISCPTLHLKLLELNIPSTLLEYDTRFSCYET-FIKYDYNSPLELP---ADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNF 637
            N+   ++   EDWQLSQFWY++ET   L D V       ++ S    I  +SCP+L+  + E++    + E+D RF  Y T F+ YD N     P    +   Q+D+I+ DPPFLS+EC+ KT + +  L  + + +K++LC+G V E      L V +C  F+P+HER L N+F  + NF
Sbjct:   35 NKTGKDAQFEEDWQLSQFWYSTETKHALRDVVRKLLAERTEDSGDFSIALLSCPSLYKDIREIHDTVHIFEFDKRFEAYGTDFVHYDLNCVGSNPDYLKEHHQQYDLIVADPPFLSQECIAKTCEIITRLQRNQKESKVILCSGEVVEPWLTARLPVLKC-SFRPEHERNLGNKFVSYANF 214
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Fly
Match: CG9154 (gene:FBgn0031777 transcript:FBtr0343128)

HSP 1 Score: 123.635 bits (309), Expect = 1.516e-34
Identity = 67/181 (37.02%), Postives = 102/181 (56.35%), Query Frame = 2 
Query:  125 NQKNTESSPSEDWQLSQFWYNSETTQKLADEVI------SQSSDSSRIVCISCPTLHLKLLELNIPSTLLEYDTRFSCYET-FIKYDYNSPLELP---ADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNF 637
            N+   ++   EDWQLSQFWY++ET   L D V       ++ S    I  +SCP+L+  + E++    + E+D RF  Y T F+ YD N     P    +   Q+D+I+ DPPFLS+EC+ KT + +  L  + + +K++LC+G V E      L V +C  F+P+HER L N+F  + NF
Sbjct:   35 NKTGKDAQFEEDWQLSQFWYSTETKHALRDVVRKLLAERTEDSGDFSIALLSCPSLYKDIREIHDTVHIFEFDKRFEAYGTDFVHYDLNCVGSNPDYLKEHHQQYDLIVADPPFLSQECIAKTCEIITRLQRNQKESKVILCSGEVVEPWLTARLPVLKC-SFRPEHERNLGNKFVSYANF 214
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Zebrafish
Match: eef1akmt1 (EEF1A lysine methyltransferase 1 [Source:NCBI gene;Acc:404619])

HSP 1 Score: 156.377 bits (394), Expect = 7.349e-48
Identity = 81/170 (47.65%), Postives = 114/170 (67.06%), Query Frame = 2 
Query:  167 LSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL------NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIENQ-FDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVL 652
            +SQFWY+ ET  +LA+E++ Q+ +  RI C+S P+++ KL +L       + + LLE+D RF+ Y + F+ YDYN+PL LP D+  Q FDI+I DPP+LSEECL K + TVK L+      KI+LCTG + EE A +LL +K C  F PKH   L+NEF C+VN+E  +L
Sbjct:    1 MSQFWYSEETASRLAEELLQQAGEHGRIACLSAPSVYQKLKQLESVRSEGVSAVLLEFDRRFAAYGDEFVFYDYNNPLCLPEDLLPQSFDIVIADPPYLSEECLSKVTLTVKHLTKG----KILLCTGAIMEEHAGKLLDLKMC-SFLPKHNHNLANEFRCYVNYESRLL 165
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Zebrafish
Match: eef1akmt1 (EEF1A lysine methyltransferase 1 [Source:NCBI gene;Acc:404619])

HSP 1 Score: 156.377 bits (394), Expect = 7.349e-48
Identity = 81/170 (47.65%), Postives = 114/170 (67.06%), Query Frame = 2 
Query:  167 LSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL------NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIENQ-FDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVL 652
            +SQFWY+ ET  +LA+E++ Q+ +  RI C+S P+++ KL +L       + + LLE+D RF+ Y + F+ YDYN+PL LP D+  Q FDI+I DPP+LSEECL K + TVK L+      KI+LCTG + EE A +LL +K C  F PKH   L+NEF C+VN+E  +L
Sbjct:    1 MSQFWYSEETASRLAEELLQQAGEHGRIACLSAPSVYQKLKQLESVRSEGVSAVLLEFDRRFAAYGDEFVFYDYNNPLCLPEDLLPQSFDIVIADPPYLSEECLSKVTLTVKHLTKG----KILLCTGAIMEEHAGKLLDLKMC-SFLPKHNHNLANEFRCYVNYESRLL 165
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Zebrafish
Match: eef1akmt1 (EEF1A lysine methyltransferase 1 [Source:NCBI gene;Acc:404619])

HSP 1 Score: 156.377 bits (394), Expect = 7.349e-48
Identity = 81/170 (47.65%), Postives = 114/170 (67.06%), Query Frame = 2 
Query:  167 LSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL------NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIENQ-FDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVL 652
            +SQFWY+ ET  +LA+E++ Q+ +  RI C+S P+++ KL +L       + + LLE+D RF+ Y + F+ YDYN+PL LP D+  Q FDI+I DPP+LSEECL K + TVK L+      KI+LCTG + EE A +LL +K C  F PKH   L+NEF C+VN+E  +L
Sbjct:    1 MSQFWYSEETASRLAEELLQQAGEHGRIACLSAPSVYQKLKQLESVRSEGVSAVLLEFDRRFAAYGDEFVFYDYNNPLCLPEDLLPQSFDIVIADPPYLSEECLSKVTLTVKHLTKG----KILLCTGAIMEEHAGKLLDLKMC-SFLPKHNHNLANEFRCYVNYESRLL 165
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Xenopus
Match: c8orf76 (chromosome 8 open reading frame 76 [Source:Xenbase;Acc:XB-GENE-972589])

HSP 1 Score: 174.866 bits (442), Expect = 2.047e-54
Identity = 93/180 (51.67%), Postives = 123/180 (68.33%), Query Frame = 2 
Query:  131 KNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVLD 655
            K +  S  EDWQLSQFWY+ ET   LA EVI    ++ RI CIS P+++ K+  L   ++   LLEYD RF+ Y + F+ YDYN PL+LP  +E + FDI+I DPP+LSEECLR T+QT+K+LS      KI+LCTG + E+LA ++L +K C KF PKH R L+NEF C+ N+E L LD
Sbjct:   41 KFSVGSVEEDWQLSQFWYSDETALSLAKEVIEVCGENGRIACISAPSIYQKVRGLARESLHVQLLEYDQRFAIYGDDFVFYDYNEPLKLPESLEQSSFDIVIADPPYLSEECLRNTAQTIKYLSRG----KIILCTGAIMEDLAAQILGLKIC-KFIPKHTRSLANEFRCYSNYE-LTLD 214
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Xenopus
Match: c8orf76 (chromosome 8 open reading frame 76 [Source:Xenbase;Acc:XB-GENE-972589])

HSP 1 Score: 175.252 bits (443), Expect = 5.077e-54
Identity = 93/180 (51.67%), Postives = 123/180 (68.33%), Query Frame = 2 
Query:  131 KNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVLD 655
            K +  S  EDWQLSQFWY+ ET   LA EVI    ++ RI CIS P+++ K+  L   ++   LLEYD RF+ Y + F+ YDYN PL+LP  +E + FDI+I DPP+LSEECLR T+QT+K+LS      KI+LCTG + E+LA ++L +K C KF PKH R L+NEF C+ N+E L LD
Sbjct:   79 KFSVGSVEEDWQLSQFWYSDETALSLAKEVIEVCGENGRIACISAPSIYQKVRGLARESLHVQLLEYDQRFAIYGDDFVFYDYNEPLKLPESLEQSSFDIVIADPPYLSEECLRNTAQTIKYLSRG----KIILCTGAIMEDLAAQILGLKIC-KFIPKHTRSLANEFRCYSNYE-LTLD 252
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Mouse
Match: Eef1akmt1 (EEF1A alpha lysine methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1915293])

HSP 1 Score: 169.088 bits (427), Expect = 3.082e-52
Identity = 83/167 (49.70%), Postives = 115/167 (68.86%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ +T  +LA E I  + +  RI C+S P+++ KL EL   +    + EYD RF+ Y + FI YDYN PLELP  I  + FD+++ DPP+LSEECLRKTS+T+++L+      KI+LCTG + EE A +LL VK C KF P+H R L+NEF C+ N++
Sbjct:   46 ENWQLSQFWYSQDTALRLAREAIDAAGEGGRIACVSAPSVYQKLRELCREDSSVYIFEYDRRFAIYGDEFIFYDYNHPLELPERIAAHSFDLVVADPPYLSEECLRKTSETIQFLTRG----KILLCTGAIMEEQAAQLLGVKMC-KFIPEHSRNLANEFRCYTNYD 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Mouse
Match: Eef1akmt1 (EEF1A alpha lysine methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1915293])

HSP 1 Score: 168.318 bits (425), Expect = 7.064e-52
Identity = 83/167 (49.70%), Postives = 115/167 (68.86%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ +T  +LA E I  + +  RI C+S P+++ KL EL   +    + EYD RF+ Y + FI YDYN PLELP  I  + FD+++ DPP+LSEECLRKTS+T+++L+      KI+LCTG + EE A +LL VK C KF P+H R L+NEF C+ N++
Sbjct:   56 ENWQLSQFWYSQDTALRLAREAIDAAGEGGRIACVSAPSVYQKLRELCREDSSVYIFEYDRRFAIYGDEFIFYDYNHPLELPERIAAHSFDLVVADPPYLSEECLRKTSETIQFLTRG----KILLCTGAIMEEQAAQLLGVKMC-KFIPEHSRNLANEFRCYTNYD 217
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q8WVE0|EFMT1_HUMAN (EEF1A lysine methyltransferase 1 OS=Homo sapiens OX=9606 GN=EEF1AKMT1 PE=1 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 5.217e-55
Identity = 90/167 (53.89%), Postives = 116/167 (69.46%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ ET  +LA E I+   +  RI C+S P+++ KL EL   N    + EYD RF+ Y E FI YDYN+PL+LP  I  + FDI+I DPP+LSEECLRKTS+TVK+L+      KI+LCTG + EE A ELL VK C  F P+H R L+NEF C+VN++
Sbjct:   46 ENWQLSQFWYSQETALQLAQEAIAAVGEGGRIACVSAPSVYQKLRELCRENFSIYIFEYDKRFAMYGEEFIFYDYNNPLDLPERIAAHSFDIVIADPPYLSEECLRKTSETVKYLTRG----KILLCTGAIMEEQAAELLGVKMC-TFVPRHTRNLANEFRCYVNYD 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q6GN98|EFMT1_XENLA (EEF1A lysine methyltransferase 1 OS=Xenopus laevis OX=8355 GN=eef1akmt1 PE=2 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 1.571e-52
Identity = 93/183 (50.82%), Postives = 123/183 (67.21%), Query Frame = 2 
Query:  125 NQKNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLELNIPST---LLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVLDE 658
            ++K +  S  EDWQLSQFWY+ ET   LA E I    ++ RI CIS P+++ KL  L   S    LLEYD RF+ Y + F+ YDYN PL+LP  +E + FDI+I DPP+LSEECL+ T+QT+K LS      KI+LCTG V E+LA + L +K+C KF P+H R L+NEF C+ N+E L LD+
Sbjct:   40 HEKFSVGSVEEDWQLSQFWYSDETALSLAKEAIEVCGENGRIACISAPSIYQKLRGLAGESVYIRLLEYDNRFAVYGDDFVFYDYNEPLKLPESLEPSSFDIVIADPPYLSEECLQNTAQTIKHLSRG----KIILCTGAVMEDLAAQKLGLKKC-KFIPEHTRNLANEFRCYSNYE-LALDK 216
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q5ZKT6|EFMT1_CHICK (EEF1A lysine methyltransferase 1 OS=Gallus gallus OX=9031 GN=EEF1AKMT1 PE=2 SV=1)

HSP 1 Score: 170.244 bits (430), Expect = 8.593e-52
Identity = 87/170 (51.18%), Postives = 114/170 (67.06%), Query Frame = 2 
Query:  143 SSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLE---LNIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPAD-IENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNF 637
             S  EDWQLSQFWY+ ET   LA+E I  +    RI C+S P+++ KL E    +    +LEYD RFS Y E FI YDYN+PL LP   + + FDI++ DPP+LSEECL+KT++T+K+L+      KI+LCTG + EE A + L VK C KF PKH R L+NEF C+VN+
Sbjct:   44 GSIEEDWQLSQFWYSDETASCLANEAIVAAGKGGRIACVSAPSVYQKLREQGGADFSVCILEYDRRFSVYGEEFIFYDYNNPLNLPEHLLPHSFDIVVADPPYLSEECLQKTAETIKYLTKG----KILLCTGAIMEEQAAKHLGVKIC-KFIPKHSRNLANEFRCYVNY 208
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q9CY45|EFMT1_MOUSE (EEF1A lysine methyltransferase 1 OS=Mus musculus OX=10090 GN=Eef1akmt1 PE=1 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 2.156e-51
Identity = 83/167 (49.70%), Postives = 115/167 (68.86%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ +T  +LA E I  + +  RI C+S P+++ KL EL   +    + EYD RF+ Y + FI YDYN PLELP  I  + FD+++ DPP+LSEECLRKTS+T+++L+      KI+LCTG + EE A +LL VK C KF P+H R L+NEF C+ N++
Sbjct:   46 ENWQLSQFWYSQDTALRLAREAIDAAGEGGRIACVSAPSVYQKLRELCREDSSVYIFEYDRRFAIYGDEFIFYDYNHPLELPERIAAHSFDLVVADPPYLSEECLRKTSETIQFLTRG----KILLCTGAIMEEQAAQLLGVKMC-KFIPEHSRNLANEFRCYTNYD 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q17QF2|EFMT1_BOVIN (EEF1A lysine methyltransferase 1 OS=Bos taurus OX=9913 GN=EEF1AKMT1 PE=2 SV=1)

HSP 1 Score: 165.622 bits (418), Expect = 7.785e-50
Identity = 81/166 (48.80%), Postives = 113/166 (68.07%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNF 637
            E+WQLSQFWY+ ET   LA++ ++ + +  RI C+S P+++ KL E    ++   + EYD RF+ Y E F+ YDY +P++LP  I  + FDI++ DPP+LSEECLRK S+T+K L+      KI+LCTG V E+ A +LL VK C KF P+H R L NEF CFVN+
Sbjct:   47 ENWQLSQFWYSPETATCLAEDAVAAAGEGGRIACVSAPSVYQKLRERHRDDVSVCIFEYDRRFAIYGEDFVYYDYKNPVDLPERIATHSFDIVVADPPYLSEECLRKMSETIKLLTRG----KILLCTGAVMEDAAAKLLGVKMC-KFIPEHTRTLGNEFRCFVNY 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. TrEMBL
Match: A0A2K6EJ59 (EEF1A lysine methyltransferase 1 OS=Propithecus coquereli OX=379532 GN=EEF1AKMT1 PE=3 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 2.232e-54
Identity = 91/167 (54.49%), Postives = 118/167 (70.66%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ ET  +LA E I+ + +  RI C+S P+++ KL EL   +    + EYD RF+ Y E FI YDYN+PL+LP  I  + FDI+I DPP+LSEECLRKTS+T+K+L+      KI+LCTG + EELA ELL VK C KF PKH R L+N F C+VN+E
Sbjct:   46 ENWQLSQFWYSQETALRLAQEAIAAAGEGGRIACVSAPSVYQKLRELHREDFSIYIFEYDKRFAMYGEEFIFYDYNNPLDLPKKIAAHSFDIVIADPPYLSEECLRKTSETIKYLTRG----KILLCTGAIMEELAAELLGVKMC-KFIPKHTRNLANAFCCYVNYE 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. TrEMBL
Match: H3A8Q5 (EEF1A lysine methyltransferase 1 OS=Latimeria chalumnae OX=7897 GN=EEF1AKMT1 PE=3 SV=1)

HSP 1 Score: 182.185 bits (461), Expect = 4.812e-54
Identity = 94/175 (53.71%), Postives = 123/175 (70.29%), Query Frame = 2 
Query:  131 KNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            K +  S  E+WQLSQFWY+SET  +LA E I+ +    +I CIS P+ + KL EL   +    +LEYD RFS Y E FI YDYN+PL LPA+++ + FDI+I DPP+LSEECL+KT+QTVK+L+      KI+LCTG V EE A +LL V+ C KF PKH R L+NEF C+VN++
Sbjct:   39 KYSIGSVEENWQLSQFWYSSETALRLAHEAIAAAGKGGKIACISAPSAYQKLKELQGEDFSVCILEYDKRFSVYGEEFIFYDYNNPLNLPANLKAHTFDIVIADPPYLSEECLKKTAQTVKYLTKG----KILLCTGAVMEECASKLLGVRMC-KFIPKHTRNLANEFRCYVNYD 208
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. TrEMBL
Match: A0A1U7QJP1 (EEF1A lysine methyltransferase 1 OS=Mesocricetus auratus OX=10036 GN=Eef1akmt1 PE=3 SV=1)

HSP 1 Score: 182.185 bits (461), Expect = 5.503e-54
Identity = 88/167 (52.69%), Postives = 122/167 (73.05%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            E+WQLSQFWY+ +T  +LA E ++ + +  RI C+S P+++ KL EL   +I + + EYD RF+ Y E F+ YDYN+PL+LP  I E+ FDI++VDPP+LSEECLRKTS+TV++L+      KI+LCTG V EE A +LL VK C KF P+H R L+NEF C+VN++
Sbjct:   46 ENWQLSQFWYSQDTALQLAQEAVAAAGEGGRIACVSAPSVYQKLRELHREDITAYIFEYDRRFAVYGEEFVFYDYNNPLDLPGRIPEHSFDIVVVDPPYLSEECLRKTSETVRFLTRG----KILLCTGAVMEEQAAQLLGVKVC-KFIPEHSRNLANEFRCYVNYD 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. TrEMBL
Match: A0A444U364 (EEF1A lysine methyltransferase 1 OS=Acipenser ruthenus OX=7906 GN=EEF1AKMT1 PE=3 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 6.964e-54
Identity = 92/167 (55.09%), Postives = 118/167 (70.66%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            EDWQLSQFWY+ ET ++LA EVIS +    +I CIS P+++ KL EL   +  + +LEYD RFS Y + F+ YDY +PL LP   E N FDI+I DPP+LSEECL KT+QTVK+L+      KI+LCTG V EE A +LL ++ C KF PKH R L+NEF C+VN+E
Sbjct:   44 EDWQLSQFWYSKETAERLAKEVISAAGKGGKIACISAPSIYQKLKELQNEDFSAFVLEYDRRFSVYGDEFVFYDYKNPLNLPEHFEPNSFDIVIADPPYLSEECLSKTAQTVKFLTKG----KILLCTGAVMEEQAAKLLGLRVC-KFIPKHNRSLANEFRCYVNYE 205
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. TrEMBL
Match: H0XTS6 (EEF1A lysine methyltransferase 1 OS=Otolemur garnettii OX=30611 GN=EEF1AKMT1 PE=3 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 7.791e-54
Identity = 91/177 (51.41%), Postives = 121/177 (68.36%), Query Frame = 2 
Query:  125 NQKNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADI-ENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            N K       E+WQLSQFWY+ ET  +LA E I+ + +  RI C+S P+++ KL +L   +    + EYD RF+ Y E FI YDYN+PL+LP  I  + FDI++ DPP+LSE+CLRKTS+T+K+L+      KI+LCTG + EELA ELL VK C KF PKH R L+NEF C+VN+E
Sbjct:   36 NDKYNIGIIEENWQLSQFWYSQETALRLAQEAIAAAGEGGRIACVSAPSVYQKLRQLHREDFSIYIFEYDKRFAVYGEEFIFYDYNNPLDLPPKIAAHSFDIVVADPPYLSEDCLRKTSETIKYLTQG----KILLCTGAIMEELAAELLGVKMC-KFIPKHTRNLANEFCCYVNYE 207
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Cavefish
Match: eef1akmt1 (EEF1A lysine methyltransferase 1 [Source:NCBI gene;Acc:103024157])

HSP 1 Score: 162.54 bits (410), Expect = 1.084e-49
Identity = 86/183 (46.99%), Postives = 116/183 (63.39%), Query Frame = 2 
Query:  137 TESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---------NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIENQ-FDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVL 652
            T  +  EDW +SQFWY+ ET  +LA+E I Q+    RI C+S P+++ KL +L          + S L E+D RF+ Y E FI YDYN+PL LP  I  Q FD +I DPP+LSEECL K + TVK L+ S    K++LCTG + EELA +L+ +K C  + PKH   L+NEF C+VN+E  +L
Sbjct:   43 TVGALKEDWHMSQFWYSDETATRLAEEAIQQAGKQGRIACVSAPSVYQKLKQLESQREDGSHGVSSVLFEFDRRFAVYGEEFIFYDYNNPLCLPEHILPQSFDFVIADPPYLSEECLSKVALTVKILTRS----KMLLCTGAIMEELAGKLMNLKIC-SYLPKHSHNLANEFRCYVNYESSLL 220
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Yeast
Match: EFM5 (S-adenosylmethionine-dependent lysine methyltransferase; involved in the trimethylation of eEF1A (Tef1p/Tef2p) at lysine 79; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in budding yeast; expresses a circular RNA; originally misclassified as a N-6-adenine specific DNA methyltransferase based on sequence similarity; both Efm5p and human ortholog N6AMT2 can methylate eEF1a from either species in vitro [Source:SGD;Acc:S000003233])

HSP 1 Score: 114.39 bits (285), Expect = 1.109e-31
Identity = 62/180 (34.44%), Postives = 102/180 (56.67%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL---NIPST---LLEYDTRF---SCYETFIKYDYNSPLELPADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTK---------IMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFE 640
            EDWQLSQFWY+ +T   LAD ++  + +++ I  +S P+++  + +     IP+    L E+D RF   +  + F  YDYN PL+   +I+ + D +++DPPFL+E+C  K+S T K L   ++++K         ++ CTG    E+  ++    +   F P+H   LSNEF C+ NFE
Sbjct:   61 EDWQLSQFWYSDDTAAILADAILEGADENTVIAIVSAPSVYAAIQKKPTNEIPTEHIYLFEFDKRFELLAGRDHFFFYDYNKPLDFSDEIKGKVDRLLIDPPFLNEDCQTKSSITAKCLLAPNDNSKTKKGVFKHRLISCTGERMSEVISKVYSDTRITTFLPEHSNGLSNEFRCYANFE 240
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Medaka
Match: eef1akmt1 (EEF1A lysine methyltransferase 1 [Source:NCBI gene;Acc:101157982])

HSP 1 Score: 173.326 bits (438), Expect = 5.685e-54
Identity = 82/169 (48.52%), Postives = 116/169 (68.64%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL------NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNF 637
            EDW++SQFWY+ ET  +LA+EV+ ++ +  RI C+S P+++ KL +        + + +LE+D RFS Y E ++ YDYN PL LP  +E   FDI++ DPP+LSEECL K ++T+K+LS      K++LCTG + E LA ELL VK C  F+P+H R LSNEF CFVN+
Sbjct:   49 EDWRMSQFWYSDETATRLAEEVVREAGEGGRIACVSAPSVYQKLKQGVVDGSERVTAVVLEFDRRFSTYREDYVFYDYNQPLSLPVSVEPRSFDIVLADPPYLSEECLSKVAETIKYLSKG----KVLLCTGAIMENLAKELLDVKMC-SFEPRHNRNLSNEFRCFVNY 212
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Medaka
Match: eef1akmt1 (EEF1A lysine methyltransferase 1 [Source:NCBI gene;Acc:101157982])

HSP 1 Score: 173.326 bits (438), Expect = 5.685e-54
Identity = 82/169 (48.52%), Postives = 116/169 (68.64%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL------NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNF 637
            EDW++SQFWY+ ET  +LA+EV+ ++ +  RI C+S P+++ KL +        + + +LE+D RFS Y E ++ YDYN PL LP  +E   FDI++ DPP+LSEECL K ++T+K+LS      K++LCTG + E LA ELL VK C  F+P+H R LSNEF CFVN+
Sbjct:   49 EDWRMSQFWYSDETATRLAEEVVREAGEGGRIACVSAPSVYQKLKQGVVDGSERVTAVVLEFDRRFSTYREDYVFYDYNQPLSLPVSVEPRSFDIVLADPPYLSEECLSKVAETIKYLSKG----KVLLCTGAIMENLAKELLDVKMC-SFEPRHNRNLSNEFRCFVNY 212
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Medaka
Match: eef1akmt1 (EEF1A lysine methyltransferase 1 [Source:NCBI gene;Acc:101157982])

HSP 1 Score: 173.326 bits (438), Expect = 5.685e-54
Identity = 82/169 (48.52%), Postives = 116/169 (68.64%), Query Frame = 2 
Query:  155 EDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLEL------NIPSTLLEYDTRFSCY-ETFIKYDYNSPLELPADIE-NQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNF 637
            EDW++SQFWY+ ET  +LA+EV+ ++ +  RI C+S P+++ KL +        + + +LE+D RFS Y E ++ YDYN PL LP  +E   FDI++ DPP+LSEECL K ++T+K+LS      K++LCTG + E LA ELL VK C  F+P+H R LSNEF CFVN+
Sbjct:   49 EDWRMSQFWYSDETATRLAEEVVREAGEGGRIACVSAPSVYQKLKQGVVDGSERVTAVVLEFDRRFSTYREDYVFYDYNQPLSLPVSVEPRSFDIVLADPPYLSEECLSKVAETIKYLSKG----KVLLCTGAIMENLAKELLDVKMC-SFEPRHNRNLSNEFRCFVNY 212
[Close]
BLAST of EEF1A lysine methyltransferase 1 vs. Planmine SMEST
Match: SMESG000060931.1 (SMESG000060931.1)

HSP 1 Score: 375.555 bits (963), Expect = 4.180e-134
Identity = 202/203 (99.51%), Postives = 203/203 (100.00%), Query Frame = 2 
Query:   50 MNLSDDEDLCXXXXXXXXXXXXXXXNQKNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLELNIPSTLLEYDTRFSCYETFIKYDYNSPLELPADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVLDE 658
            MNLSDDEDLCLSPEAALALSEFLAENQKNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLELNIPSTLLEYDTRFSCYETFIKYDYNSPLELPADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKI+LCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVLDE
Sbjct:    1 MNLSDDEDLCLSPEAALALSEFLAENQKNTESSPSEDWQLSQFWYNSETTQKLADEVISQSSDSSRIVCISCPTLHLKLLELNIPSTLLEYDTRFSCYETFIKYDYNSPLELPADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDESTKIILCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLVLDE 203
The following BLAST results are available for this feature:
BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
EEF1AKMT11.086e-5553.89EEF1A lysine methyltransferase 1 [Source:HGNC Symb... [more]
EEF1AKMT11.086e-5553.89EEF1A lysine methyltransferase 1 [Source:HGNC Symb... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
M142.82.448e-4341.90Protein-lysine N-methyltransferase M142.8 [Source... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG91541.516e-3437.02gene:FBgn0031777 transcript:FBtr0079213[more]
CG91541.516e-3437.02gene:FBgn0031777 transcript:FBtr0343128[more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
eef1akmt17.349e-4847.65EEF1A lysine methyltransferase 1 [Source:NCBI gene... [more]
eef1akmt17.349e-4847.65EEF1A lysine methyltransferase 1 [Source:NCBI gene... [more]
eef1akmt17.349e-4847.65EEF1A lysine methyltransferase 1 [Source:NCBI gene... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
c8orf762.047e-5451.67chromosome 8 open reading frame 76 [Source:Xenbase... [more]
c8orf765.077e-5451.67chromosome 8 open reading frame 76 [Source:Xenbase... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Eef1akmt13.082e-5249.70EEF1A alpha lysine methyltransferase 1 [Source:MGI... [more]
Eef1akmt17.064e-5249.70EEF1A alpha lysine methyltransferase 1 [Source:MGI... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8WVE0|EFMT1_HUMAN5.217e-5553.89EEF1A lysine methyltransferase 1 OS=Homo sapiens O... [more]
sp|Q6GN98|EFMT1_XENLA1.571e-5250.82EEF1A lysine methyltransferase 1 OS=Xenopus laevis... [more]
sp|Q5ZKT6|EFMT1_CHICK8.593e-5251.18EEF1A lysine methyltransferase 1 OS=Gallus gallus ... [more]
sp|Q9CY45|EFMT1_MOUSE2.156e-5149.70EEF1A lysine methyltransferase 1 OS=Mus musculus O... [more]
sp|Q17QF2|EFMT1_BOVIN7.785e-5048.80EEF1A lysine methyltransferase 1 OS=Bos taurus OX=... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2K6EJ592.232e-5454.49EEF1A lysine methyltransferase 1 OS=Propithecus co... [more]
H3A8Q54.812e-5453.71EEF1A lysine methyltransferase 1 OS=Latimeria chal... [more]
A0A1U7QJP15.503e-5452.69EEF1A lysine methyltransferase 1 OS=Mesocricetus a... [more]
A0A444U3646.964e-5455.09EEF1A lysine methyltransferase 1 OS=Acipenser ruth... [more]
H0XTS67.791e-5451.41EEF1A lysine methyltransferase 1 OS=Otolemur garne... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
eef1akmt11.084e-4946.99EEF1A lysine methyltransferase 1 [Source:NCBI gene... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
EFM51.109e-3134.44S-adenosylmethionine-dependent lysine methyltransf... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of EEF1A lysine methyltransferase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
eef1akmt15.685e-5448.52EEF1A lysine methyltransferase 1 [Source:NCBI gene... [more]
eef1akmt15.685e-5448.52EEF1A lysine methyltransferase 1 [Source:NCBI gene... [more]
eef1akmt15.685e-5448.52EEF1A lysine methyltransferase 1 [Source:NCBI gene... [more]
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BLAST of EEF1A lysine methyltransferase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000060931.14.180e-13499.51SMESG000060931.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016770 ID=SMED30016770|Name=EEF1A lysine methyltransferase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=693bp
TGTGATTTGGAAAGGTTTGTTTAAATAATATTCAATTAAATGTGTTAGAA
TGAATTTAAGCGATGATGAAGATTTATGTTTGTCTCCCGAAGCTGCTTTA
GCTCTTTCAGAATTTTTAGCAGAAAATCAAAAAAATACTGAATCAAGTCC
TTCCGAAGACTGGCAATTGTCTCAATTTTGGTACAATTCAGAAACCACAC
AAAAATTGGCTGATGAAGTAATATCTCAGAGTTCAGATTCATCAAGAATA
GTATGCATAAGTTGTCCAACATTACACCTGAAATTACTTGAACTTAATAT
TCCTTCAACACTTTTAGAATACGACACAAGGTTTAGTTGTTATGAAACAT
TTATCAAATATGATTATAACTCTCCTCTTGAATTACCTGCTGATATTGAA
AATCAATTTGATATTATCATAGTAGATCCTCCTTTTTTAAGTGAAGAATG
TCTTCGAAAGACTAGTCAAACAGTCAAATGGCTCTCTAACTCTGATGAAT
CAACTAAAATAATGCTATGTACTGGAAGAGTTCAGGAAGAATTAGCACTT
GAGCTGTTGTGTGTGAAACAATGTAAAAAGTTTCAGCCAAAACACGAGCG
TCAGCTTTCAAATGAATTCGGCTGTTTTGTTAATTTTGAACCGCTGGTTT
TAGATGAATAAAAATAATGTTTTGTTTACTGAAAAAAGTTGCA
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protein sequence of SMED30016770-orf-1

>SMED30016770-orf-1 ID=SMED30016770-orf-1|Name=SMED30016770-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=204bp
MNLSDDEDLCLSPEAALALSEFLAENQKNTESSPSEDWQLSQFWYNSETT
QKLADEVISQSSDSSRIVCISCPTLHLKLLELNIPSTLLEYDTRFSCYET
FIKYDYNSPLELPADIENQFDIIIVDPPFLSEECLRKTSQTVKWLSNSDE
STKIMLCTGRVQEELALELLCVKQCKKFQPKHERQLSNEFGCFVNFEPLV
LDE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR041370Mlase_EEF1AKMT1/ZCCHC4
IPR029063SAM-dependent_MTases
IPR019369Efm5/EEF1AKMT1
IPR002052DNA_methylase_N6_adenine_CS
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity
GO:0003676nucleic acid binding
GO:0016279protein-lysine N-methyltransferase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0032259methylation
GO:0006479protein methylation
GO:0018022peptidyl-lysine methylation
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005829cytosol
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR041370Methyltransferase EEF1AKMT1/ZCCHC4PFAMPF10237N6-adenineMlasecoord: 36..197
e-value: 1.4E-51
score: 174.5
IPR019369Protein-lysine N-methyltransferase Efm5/EEF1AKMT1PANTHERPTHR13200UNCHARACTERIZEDcoord: 4..198
NoneNo IPR availablePANTHERPTHR13200:SF0EEF1A LYSINE METHYLTRANSFERASE 1coord: 4..198
IPR002052DNA methylase, N-6 adenine-specific, conserved sitePROSITEPS00092N6_MTASEcoord: 123..129