HATPase_c domain-containing protein

Overview


Name	HATPase_c domain-containing protein
Smed ID	SMED30016760
Length (bp)	4348

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of HATPase_c domain-containing protein (SMED30016760) t-SNE clustered cells

Violin plots show distribution of expression levels for HATPase_c domain-containing protein (SMED30016760) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HATPase_c domain-containing protein (SMED30016760) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HATPase_c domain-containing protein (SMED30016760) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016760

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 31

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Lifecycle
head region	SMED30016760	h1SMcG0006787	SmedASXL_061618	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
cephalic ganglia	SMED30016760	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30016760	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30016760	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig563	GPL15192	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016760	h1SMcG0006787	dd_Smed_v4_3684_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30016760	h1SMcG0006787	dd_Smed_v4_3684_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30016760	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016760	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30016760	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30016760	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30016760	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0019490	Contig563	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig31297	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig31297	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig32555	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig32555	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig38791	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig38791	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig39149	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006787	Contig39149	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006788	Contig39149	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016760	h1SMcG0006788	Contig39149	newmark_ests	PMID:29674431 Fincher et al., 2018
head region	SMED30016760	h1SMcG0006787	dd_Smed_v6_1693_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
pharynx musculature	SMED30016760	h1SMcG0006787	dd_Smed_v6_2265_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30016760	h1SMcG0006787	dd_Smed_v6_2265_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
pharynx musculature	SMED30016760	h1SMcG0006787	dd_Smed_v6_1693_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30016760	h1SMcG0006787	dd_Smed_v6_1693_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
reproductive organ	SMED30016760	h1SMcG0006787	Contig15693	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30016760	h1SMcG0006787	Contig15693	newmark_ests	PMID:28434803 Rouhana et al., 2017
testis primordium	SMED30016760	h1SMcG0006787	Contig5941_SE3	GPL10652	PMID:20844018 Wang et al., 2010	juvenile stage

Note: Hover over icons to view figure legend

Homology

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BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Match: HSP90B1 (heat shock protein 90 beta family member 1 [Source:HGNC Symbol;Acc:HGNC:12028])

HSP 1 Score: 342.043 bits (876), Expect = 1.911e-106
Identity = 174/262 (66.41%), Postives = 219/262 (83.59%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSS 284

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BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Match: HSP90B1 (heat shock protein 90 beta family member 1 [Source:HGNC Symbol;Acc:HGNC:12028])

HSP 1 Score: 342.043 bits (876), Expect = 1.970e-106
Identity = 174/262 (66.41%), Postives = 219/262 (83.59%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSS 284

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BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Match: HSP90B1 (heat shock protein 90 beta family member 1 [Source:HGNC Symbol;Acc:HGNC:12028])

HSP 1 Score: 339.732 bits (870), Expect = 1.500e-99
Identity = 174/262 (66.41%), Postives = 219/262 (83.59%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSS 284

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BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 207.994 bits (528), Expect = 3.851e-55
Identity = 110/211 (52.13%), Postives = 151/211 (71.56%), Query Frame = 2

Query:  353 EKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L+I +  +K  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     VR   G  + RGT+VILHLK++  E+LE   ++ ++ K+SQFI +PI L+
Sbjct:   15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLF 221

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BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 208.379 bits (529), Expect = 1.316e-54
Identity = 112/211 (53.08%), Postives = 151/211 (71.56%), Query Frame = 2

Query:  353 EKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L+I +  +K  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F+    EA   G    +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     VR   G  + RGT+VILHLK++  E+LE   ++ ++ K+SQFI +PI L+
Sbjct:  137 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLF 343

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BLAST of HATPase_c domain-containing protein vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 294.664 bits (753), Expect = 1.241e-84
Identity = 149/231 (64.50%), Postives = 198/231 (85.71%), Query Frame = 2

Query:  302 EAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSE-AKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            ++I +DGL+VSQIKELR KAEK+ FQAEV+RMMKLIINSLY+NKEIFLRELISNASDALDKIR +SLT+ ++  + E++ +KIKAD+  + +HI DTGVGMT+ +LI NLGTIA+SGTS+F+ KL + A ++ +  +LIGQFGVGFY++FLVAD+V V +K++ D QYIWESD+++F+I +DPRGNTL+RGT++ L+LK+E  +FLE D L+NL+HKYSQFINF I+LW+S
Sbjct:   42 DSIKLDGLSVSQIKELRSKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQS 272

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Query:  302 EAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSE-AKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            ++I +DGL+VSQIKELR KAEK+ FQAEV+RMMKLIINSLY+NKEIFLRELISNASDALDKIR +SLT+ ++  + E++ +KIKAD+  + +HI DTGVGMT+ +LI NLGTIA+SGTS+F+ KL + A ++ +  +LIGQFGVGFY++FLVAD+V V +K++ D QYIWESD+++F+I +DPRGNTL+RGT++ L+LK+E  +FLE D L+NL+HKYSQFINF I+LW+S
Sbjct:   42 DSIKLDGLSVSQIKELRSKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQS 272

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BLAST of HATPase_c domain-containing protein vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 251.136 bits (640), Expect = 2.256e-70
Identity = 127/200 (63.50%), Postives = 170/200 (85.00%), Query Frame = 2

Query:  395 MMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSE-AKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            MMKLIINSLY+NKEIFLRELISNASDALDKIR +SLT+ ++  + E++ +KIKAD+  + +HI DTGVGMT+ +LI NLGTIA+SGTS+F+ KL + A ++ +  +LIGQFGVGFY++FLVAD+V V +K++ D QYIWESD+++F+I +DPRGNTL+RGT++ L+LK+E  +FLE D L+NL+HKYSQFINF I+LW+S
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQS 200

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Query:  395 MMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSE-AKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            MMKLIINSLY+NKEIFLRELISNASDALDKIR +SLT+ ++  + E++ +KIKAD+  + +HI DTGVGMT+ +LI NLGTIA+SGTS+F+ KL + A ++ +  +LIGQFGVGFY++FLVAD+V V +K++ D QYIWESD+++F+I +DPRGNTL+RGT++ L+LK+E  +FLE D L+NL+HKYSQFINF I+LW+S
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQS 200

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Query:  395 MMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSE-AKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            MMKLIINSLY+NKEIFLRELISNASDALDKIR +SLT+ ++  + E++ +KIKAD+  + +HI DTGVGMT+ +LI NLGTIA+SGTS+F+ KL + A ++ +  +LIGQFGVGFY++FLVAD+V V +K++ D QYIWESD+++F+I +DPRGNTL+RGT++ L+LK+E  +FLE D L+NL+HKYSQFINF I+LW+S
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQS 200

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BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Gp93 (gene:FBgn0039562 transcript:FBtr0085254)

HSP 1 Score: 310.457 bits (794), Expect = 9.378e-90
Identity = 162/263 (61.60%), Postives = 213/263 (80.99%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSE-AKNTG-ELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            DEA +   +  ++   KE S+TD E +KREEEAI +DGLNV+Q+KE+REKA+K+TFQ EV+RMMKLIINSLY+NKEIFLRELISNASDA+DKIR ++L+N      N +L+I+IKADK  K +HI+D+G+GMT  +LI NLGTIAKSGT+DF+ K+ + +K+ G ++N++IGQFGVGFYS+FLVAD+V V +K + D QYIWESDA++FSI  DPRG+TL+RG+ + L+LK+E  +FLE D +R LI KYSQFINFPI +W S
Sbjct:   22 DEAATTETIDLDLGSFKEGSRTDAETLKREEEAIQLDGLNVAQLKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLLALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSKSEGLDMNDMIGQFGVGFYSAFLVADRVVVTTKHNDDKQYIWESDANSFSITEDPRGDTLKRGSVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRMWSS 284

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BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0332873)

HSP 1 Score: 208.764 bits (530), Expect = 7.334e-56
Identity = 110/212 (51.89%), Postives = 155/212 (73.11%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
            + E+AE + FQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR+ SLT+  +    ++LYIK+  +K A T+ I+DTG+GMTK++L+ NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVADKVTV SK++ D QY+WES A     VR      L RGT+++L++K++  ++LE   ++ +++K+SQFI +PI L
Sbjct:    1 MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKL 208

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BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0073040)

HSP 1 Score: 208.764 bits (530), Expect = 7.334e-56
Identity = 110/212 (51.89%), Postives = 155/212 (73.11%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
            + E+AE + FQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR+ SLT+  +    ++LYIK+  +K A T+ I+DTG+GMTK++L+ NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVADKVTV SK++ D QY+WES A     VR      L RGT+++L++K++  ++LE   ++ +++K+SQFI +PI L
Sbjct:    1 MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKL 208

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BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0086149)

HSP 1 Score: 152.525 bits (384), Expect = 1.824e-37
Identity = 90/215 (41.86%), Postives = 137/215 (63.72%), Query Frame = 2

Query:  362 EKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNED--LYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKL---SEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQ--YIWESDAS-TFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
            +K+ FQAE  +++ ++  SLY + E+F+RELISNASDAL+K R+ SL+    N   +D  L I+I  DK    + I DTG+GMTK EL+ NLGTIA+SG+  F++++    +  ++   + +IGQFGVGFYSSF+VA+KV V +++         W +D S T+ I   P    +E GT ++LHLK +  E+ + + ++ +I KYS F+  PI L
Sbjct:   64 DKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVP---DVELGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL 275

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BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0336666)

HSP 1 Score: 152.525 bits (384), Expect = 1.824e-37
Identity = 90/215 (41.86%), Postives = 137/215 (63.72%), Query Frame = 2

Query:  362 EKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNED--LYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKL---SEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQ--YIWESDAS-TFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
            +K+ FQAE  +++ ++  SLY + E+F+RELISNASDAL+K R+ SL+    N   +D  L I+I  DK    + I DTG+GMTK EL+ NLGTIA+SG+  F++++    +  ++   + +IGQFGVGFYSSF+VA+KV V +++         W +D S T+ I   P    +E GT ++LHLK +  E+ + + ++ +I KYS F+  PI L
Sbjct:   64 DKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVP---DVELGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL 275

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BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 333.183 bits (853), Expect = 1.617e-97
Identity = 171/272 (62.87%), Postives = 224/272 (82.35%), Query Frame = 2

Query:  200 KIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            K  D+ D +  ++E++ KS++ S+TDDEVV+REEEAI +DGLN SQ+KE+R+KAEK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR +SLTN+D    NE+L IKIK+DK    +HI DTG+GMTK EL+KNLGTIAKSGTS+F+ K++E ++  +  +ELIGQFGVGFYS+FLVADKV V SK + D Q++WESD++ FS++ DPRG+TL RGT + L +K+E  ++LE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   20 KADDDVDIDGTVEEDLGKSRDGSRTDDEVVQREEEAIQLDGLNTSQLKEIRDKAEKHAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTNEDALAGNEELTIKIKSDKEKNMLHITDTGIGMTKEELVKNLGTIAKSGTSEFLNKMTEVQDDSQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHMWESDSNQFSVIEDPRGDTLGRGTTITLVMKEEASDYLELETIKNLVKKYSQFINFPIYVWSSKTETVEE 291

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BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 331.257 bits (848), Expect = 1.736e-96
Identity = 168/261 (64.37%), Postives = 219/261 (83.91%), Query Frame = 2

Query:  233 LKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            ++E++ KS++ S+TDDEVV+REEEAI +DGLN SQ+KE+R+KAEK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR +SLTN+D    NE+L IKIK+DK    +HI DTG+GMTK EL+KNLGTIAKSGTS+F+ K++E ++  +  +ELIGQFGVGFYS+FLVADKV V SK + D Q++WESD++ FS++ DPRG+TL RGT + L +K+E  ++LE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   32 VEEDLGKSRDGSRTDDEVVQREEEAIQLDGLNTSQLKEIRDKAEKHAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTNEDALAGNEELTIKIKSDKEKNMLHITDTGIGMTKEELVKNLGTIAKSGTSEFLNKMTEVQDDSQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHMWESDSNQFSVIEDPRGDTLGRGTTITLVMKEEASDYLELETIKNLVKKYSQFINFPIYVWSSKTETVEE 292

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BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 207.608 bits (527), Expect = 2.740e-55
Identity = 114/223 (51.12%), Postives = 158/223 (70.85%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPI--YLWKSSVKNVD 1009
            + E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    +DL I++  D+  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QYIWES A     V+   G ++ RGT+VILHLK++  E++E   ++ ++ K+SQFI +PI  Y+ K   K VD
Sbjct:   10 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEVD 228

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Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPI--YLWKSSVKNVD 1009
            + E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    +DL I++  D+  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QYIWES A     V+   G ++ RGT+VILHLK++  E++E   ++ ++ K+SQFI +PI  Y+ K   K VD
Sbjct:   10 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEVD 228

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BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 202.986 bits (515), Expect = 9.523e-54
Identity = 106/206 (51.46%), Postives = 146/206 (70.87%), Query Frame = 2

Query:  368 YTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            + FQAE+ ++M LIIN+ Y NKEIFLREL+SNASDALDKIR+ SLT+  +    +DL I I  +   +T+ ++DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     V+   G  + RGT+VILHLK++  E++E   ++ ++ K+SQFI +PI L+
Sbjct:   14 FAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLY 215

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BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 328.176 bits (840), Expect = 3.941e-97
Identity = 172/269 (63.94%), Postives = 220/269 (81.78%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE + +  ++++I KS++ S+TDDEVV REEEAI IDGLN +QIKELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L IKIK DK    +HI DTG+GMTK +L+KNLGTIAKSGTS+F+ KL++A+  G+  +ELIGQFGVGFYS+FLVAD+V V SK + D Q+IWESD++ F +  DPRG+TL RGT + L LK+E  ++LE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   25 DEVEVDATVEDDIGKSRDGSRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEE 293

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BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 329.717 bits (844), Expect = 3.234e-96
Identity = 172/269 (63.94%), Postives = 220/269 (81.78%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE + +  ++++I KS++ S+TDDEVV REEEAI IDGLN +QIKELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L IKIK DK    +HI DTG+GMTK +L+KNLGTIAKSGTS+F+ KL++A+  G+  +ELIGQFGVGFYS+FLVAD+V V SK + D Q+IWESD++ F +  DPRG+TL RGT + L LK+E  ++LE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   25 DEVEVDATVEDDIGKSRDGSRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEE 293

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 328.946 bits (842), Expect = 5.035e-96
Identity = 172/269 (63.94%), Postives = 220/269 (81.78%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE + +  ++++I KS++ S+TDDEVV REEEAI IDGLN +QIKELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L IKIK DK    +HI DTG+GMTK +L+KNLGTIAKSGTS+F+ KL++A+  G+  +ELIGQFGVGFYS+FLVAD+V V SK + D Q+IWESD++ F +  DPRG+TL RGT + L LK+E  ++LE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   23 DEVEVDATVEDDIGKSRDGSRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEE 291

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 329.331 bits (843), Expect = 6.730e-96
Identity = 172/269 (63.94%), Postives = 220/269 (81.78%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE + +  ++++I KS++ S+TDDEVV REEEAI IDGLN +QIKELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L IKIK DK    +HI DTG+GMTK +L+KNLGTIAKSGTS+F+ KL++A+  G+  +ELIGQFGVGFYS+FLVAD+V V SK + D Q+IWESD++ F +  DPRG+TL RGT + L LK+E  ++LE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   23 DEVEVDATVEDDIGKSRDGSRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEE 291

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 329.331 bits (843), Expect = 7.023e-96
Identity = 172/269 (63.94%), Postives = 220/269 (81.78%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE + +  ++++I KS++ S+TDDEVV REEEAI IDGLN +QIKELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L IKIK DK    +HI DTG+GMTK +L+KNLGTIAKSGTS+F+ KL++A+  G+  +ELIGQFGVGFYS+FLVAD+V V SK + D Q+IWESD++ F +  DPRG+TL RGT + L LK+E  ++LE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   23 DEVEVDATVEDDIGKSRDGSRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEE 291

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BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 343.584 bits (880), Expect = 5.229e-101
Identity = 176/269 (65.43%), Postives = 223/269 (82.90%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEE 291

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 208.764 bits (530), Expect = 1.590e-55
Identity = 110/211 (52.13%), Postives = 150/211 (71.09%), Query Frame = 2

Query:  353 EKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L+I +   K  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     VR   G  + RGT+VILHLK++  E+LE   ++ ++ K+SQFI +PI L+
Sbjct:   15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLF 221

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Query:  353 EKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L+I +   K  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     VR   G  + RGT+VILHLK++  E+LE   ++ ++ K+SQFI +PI L+
Sbjct:   15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLF 221

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BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 191.045 bits (484), Expect = 7.735e-55
Identity = 102/189 (53.97%), Postives = 135/189 (71.43%), Query Frame = 2

Query:  353 EKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLE 919
            E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L+I +   K  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     VR   G  + RGT+VILHLK++  E+LE
Sbjct:   15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADI----SMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLE 199

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BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Match: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1 [Source:MGI Symbol;Acc:MGI:96247])

HSP 1 Score: 202.986 bits (515), Expect = 1.032e-53
Identity = 107/206 (51.94%), Postives = 145/206 (70.39%), Query Frame = 2

Query:  368 YTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            + FQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR+ SLT+  +    ++L I I  +   +T+ ++DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KV VI+K + D QY WES A     VR   G  + RGT+VILHLK++  E+LE   ++ ++ K+SQFI +PI L+
Sbjct:   15 FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLY 216

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BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|Q66HD0|ENPL_RAT (Endoplasmin OS=Rattus norvegicus OX=10116 GN=Hsp90b1 PE=1 SV=2)

HSP 1 Score: 343.969 bits (881), Expect = 2.661e-100
Identity = 176/272 (64.71%), Postives = 224/272 (82.35%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDEDHE 1021
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK D+    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S  + V+E  E
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDREKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEEPLE 294

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BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|P08113|ENPL_MOUSE (Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE=1 SV=2)

HSP 1 Score: 343.584 bits (880), Expect = 3.658e-100
Identity = 176/269 (65.43%), Postives = 223/269 (82.90%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEE 291

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BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|Q95M18|ENPL_BOVIN (Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 SV=1)

HSP 1 Score: 341.658 bits (875), Expect = 1.593e-99
Identity = 175/267 (65.54%), Postives = 221/267 (82.77%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNV 1006
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S  + V
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETV 289

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BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|P41148|ENPL_CANLF (Endoplasmin OS=Canis lupus familiaris OX=9615 GN=HSP90B1 PE=1 SV=1)

HSP 1 Score: 340.502 bits (872), Expect = 4.879e-99
Identity = 174/262 (66.41%), Postives = 219/262 (83.59%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSS 284

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BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Match: sp|Q29092|ENPL_PIG (Endoplasmin OS=Sus scrofa OX=9823 GN=HSP90B1 PE=2 SV=3)

HSP 1 Score: 340.502 bits (872), Expect = 4.975e-99
Identity = 174/265 (65.66%), Postives = 221/265 (83.40%), Query Frame = 2

Query:  200 KIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            + +DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S
Sbjct:   20 RAEDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMAEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSS 284

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BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: A0A2R4NBU5 (Heat shock protein 902 OS=Dugesia japonica OX=6161 GN=hsp902 PE=2 SV=1)

HSP 1 Score: 488.034 bits (1255), Expect = 1.231e-150
Identity = 263/331 (79.46%), Postives = 291/331 (87.92%), Query Frame = 2

Query:   83 MKNLIYLFFIILVFSIAYRCDDETAK------QTEQQMKDSTDESKIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDEDHESAVSKRDEDANV 1057
            MK L YL  IILVFS+A+R  D+  K        E+Q  D   +SK +++     K++ENI KSKE SKTDDEV+KREEEAISIDGLNVSQIKELR+KAEK+TF+AEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQD+NFDNEDLYIKIKADK AKTIHI DTG+GMTK ELI NLGTIAKSGTSDFI+KLSEAKN+ E+NELIGQFGVGFYSSFLVAD+VTVISKS+AD+QYIWESDAS+F+I RDPRG+TLERGTEVILHLKDEVLEFLEIDVL NLIHKYSQFINFPIYLWKSSVKNV++  E AV+K DEDANV
Sbjct:    1 MKQLCYLCLIILVFSVAFRSADKNLKAESNDESIEKQTNDMNGDSKHENDLKLEPKVEENIVKSKESSKTDDEVIKREEEAISIDGLNVSQIKELRDKAEKFTFKAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDKNFDNEDLYIKIKADKIAKTIHIRDTGIGMTKNELINNLGTIAKSGTSDFIKKLSEAKNSVEMNELIGQFGVGFYSSFLVADRVTVISKSEADHQYIWESDASSFTIARDPRGDTLERGTEVILHLKDEVLEFLEIDVLSNLIHKYSQFINFPIYLWKSSVKNVEDVKEVAVTKNDEDANV 331

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BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: A0A2R4NBU1 (Heat shock protein 903 OS=Dugesia japonica OX=6161 GN=hsp903 PE=2 SV=1)

HSP 1 Score: 380.563 bits (976), Expect = 4.570e-111
Identity = 207/297 (69.70%), Postives = 247/297 (83.16%), Query Frame = 2

Query:  185 STDESKIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE------DHESAVSKRDEDANV 1057
            S  ES +K E D ++K+ E+I KSK+ SKTDDEVVKREEEAI+IDGLNV+Q+KELREKAEK+ FQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLT+       +DL IKIKADK  K++HI+DTGVGMTK +LI NLGTIAKSGTSDF++KLS++K+T E+ +LIGQFGVGFYS+FLVADKVTVISK + D Q+IWESDA++FS+V DPRGNTL+RGTE+ILHLK+E  E+LE + L+NL+ KYSQFINFPIYLW S  + VDE      + E    K+D+D  V
Sbjct:   24 SQSESHVKSETD-DVKVNEDILKSKQGSKTDDEVVKREEEAINIDGLNVAQMKELREKAEKFAFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTDSTALDAAKDLLIKIKADKDGKSLHIIDTGVGMTKQDLITNLGTIAKSGTSDFLKKLSDSKSTVEMGDLIGQFGVGFYSTFLVADKVTVISKHNDDKQHIWESDANSFSVVEDPRGNTLQRGTEIILHLKEEAHEYLEPEALKNLVTKYSQFINFPIYLWASKTETVDEPADKPVEPEKTTEKKDDDVTV 319

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BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: A0A4W2IA49 (Heat shock protein 90 beta family member 1 OS=Bos indicus x Bos taurus OX=30522 GN=HSP90B1 PE=4 SV=1)

HSP 1 Score: 343.584 bits (880), Expect = 2.896e-104
Identity = 174/264 (65.91%), Postives = 220/264 (83.33%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSV 997
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S +
Sbjct:   23 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKI 286

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BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: A0A1I8J8H1 (HATPase_c domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 348.206 bits (892), Expect = 4.792e-104
Identity = 183/256 (71.48%), Postives = 220/256 (85.94%), Query Frame = 2

Query:  239 ENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNV 1006
            E     K  SKTDD VV+REE+AI +DGLN +Q+KELREKAEK+TFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRF+SLTN++     +DL I+IKADK AKT+H++DTG+GMTK +L+KNLGTIAKSGTS+F  K +EAK+  E+ +LIGQFGVGFYS+FLVAD+VTVI+K++ D QYIWESDAS+FSI  DPRGNTL+RGTE+ILH+KDE L++LE   LR+LI KYSQFINFPIY+W+S  + V
Sbjct:    2 EPTGSDKVGSKTDDRVVEREEQAIKLDGLNAAQVKELREKAEKFTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFLSLTNKEVLSATDDLSIRIKADKDAKTLHVIDTGIGMTKEDLVKNLGTIAKSGTSEFFNKFNEAKSQTEMTDLIGQFGVGFYSAFLVADRVTVITKNNDDKQYIWESDASSFSINEDPRGNTLKRGTEIILHMKDEGLDWLEPSSLRDLIVKYSQFINFPIYVWESRTETV 257

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BLAST of HATPase_c domain-containing protein vs. TrEMBL
Match: G9K4W5 (Heat shock protein 90kDa beta, member 1 (Fragment) OS=Mustela putorius furo OX=9669 PE=2 SV=1)

HSP 1 Score: 342.813 bits (878), Expect = 8.179e-104
Identity = 174/262 (66.41%), Postives = 219/262 (83.59%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            DE D +  ++E++ KS+E S+TDDEVV+REEEAI +DGLN SQI+ELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR ISLT+++    NE+L +KIK DK    +H+ DTGVGMT+ EL+KNLGTIAKSGTS+F+ K++EA+  G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRGNTL RGT + L LK+E  ++LE+D ++NL+ KYSQFINFPIY+W S
Sbjct:   30 DEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSS 291

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BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 330.487 bits (846), Expect = 1.487e-96
Identity = 169/267 (63.30%), Postives = 220/267 (82.40%), Query Frame = 2

Query:  200 KIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSV 997
            K +D+ D +  +++++ KS++ S+TDDEVV+REEEAI +DGLN +QIKE+REK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR +SLTN D    NE+L +KIKADK    +HI DTG+GMTK EL+KNLGTIAKSGTS+F+ K++E ++ G+  +ELIGQFGVGFYS+FLVAD V V SK + D Q+IWESD++ FS++ DPRG+TL RGT + L LK+E  ++LE++ ++NL+ KYSQFINFPIY+W   +
Sbjct:   20 KAEDDIDVDGTVEDDLGKSRDGSRTDDEVVQREEEAIQLDGLNAAQIKEIREKSEKHVFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTNDDALAGNEELTVKIKADKEKNMLHITDTGIGMTKEELVKNLGTIAKSGTSEFLNKMTEMQSEGQSTSELIGQFGVGFYSAFLVADSVIVTSKHNNDTQHIWESDSNEFSVIEDPRGDTLGRGTTITLVLKEEASDYLELETIKNLVRKYSQFINFPIYVWSRPI 286

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BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 204.912 bits (520), Expect = 2.079e-54
Identity = 108/213 (50.70%), Postives = 151/213 (70.89%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            + E  E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    +DL I++  D   +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA++VTVI+K + D QY+WES A     V+   G ++ RGT+VILHLK++  E+ E   ++ ++ K+SQFI +PI L+
Sbjct:   10 MEEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPDNGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLF 218

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Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            + E  E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    +DL I++  D   +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA++VTVI+K + D QY+WES A     V+   G ++ RGT+VILHLK++  E+ E   ++ ++ K+SQFI +PI L+
Sbjct:   10 MEEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPDNGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLF 218

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BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 202.601 bits (514), Expect = 1.137e-53
Identity = 109/213 (51.17%), Postives = 151/213 (70.89%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            + ++AE + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT   +    +DL I+I  +K  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     V+      + RGT+VILHLK++  E++E   ++ ++ K+SQFI +PI L+
Sbjct:    9 MEDEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTEPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDNSEPVNRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLY 217

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BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 201.83 bits (512), Expect = 2.127e-53
Identity = 109/213 (51.17%), Postives = 149/213 (69.95%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            + E  E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT   +    +DL I+I  +K  +T+ I+DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     V+      + RGT+VILHLK++  E++E   ++ ++ K+SQFI +PI L+
Sbjct:   10 MEEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTEPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDNSEPVNRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLY 218

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BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 271.937 bits (694), Expect = 3.972e-77
Identity = 147/273 (53.85%), Postives = 189/273 (69.23%), Query Frame = 2

Query:  185 STDESKIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMT---KTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS 991
            S D+S +    D +  +++++ KS+E S+TDDEVV+REEEAI++DGLN +QIKELREKAEK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR +SLT+                         LD    +T   K +  KNL  I       F+ +  E    G+  +ELIGQFGVGFYS+FLVAD++ V SK + D Q+IWESD+S F++  DPRGNTL RGT + L LK+E  ++LE++ ++NL+ KYSQFINFPIY+W S
Sbjct:   21 SADDSTV----DGDATVEQDLGKSREGSRTDDEVVQREEEAITLDGLNAAQIKELREKAEKHVFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTD----------------------GKALDATDELTIKIKADKEKNLLHI-------FLSRAQELATEGQSTSELIGQFGVGFYSAFLVADRIVVTSKHNNDTQHIWESDSSEFTVTEDPRGNTLARGTTITLVLKEEAADYLELETIKNLVKKYSQFINFPIYVWSS 260

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BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003399.1 (pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 gene:ENSPMAG00000002912.1 transcript:ENSPMAT00000003399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 158.688 bits (400), Expect = 4.443e-40
Identity = 85/211 (40.28%), Postives = 133/211 (63.03%), Query Frame = 2

Query:  353 EKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +                      +D+G  + K ++I N     ++  + F++ L    +      +IGQFGVGFYS++L+A++V+V++K + D QY+WES A     VR   G ++ RGT+++LHLK++  E+LE   +++++ K+SQFI +PI L+
Sbjct:   12 EETETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSK----------------------MDSGKEL-KIDVIPN-----RNERTAFMEALQAGADIS----MIGQFGVGFYSAYLIAERVSVVTKHNDDEQYLWESSAGGSFTVRLDNGESIGRGTKIVLHLKEDQSEYLEEKRIKDIVKKHSQFIGYPITLF 190

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BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 111.309 bits (277), Expect = 6.713e-27
Identity = 75/203 (36.95%), Postives = 115/203 (56.65%), Query Frame = 2

Query:  464 ASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDA-STFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW--KSSVKNVDEDHESAVSKRDEDANVKP 1063
            ++ ALDKIR+ SLT+  +                      LDTG  + K ++I N   I ++ T        EA   G    +IGQFGVGFYS++LVA++VTV++K + D QY+WES A  +F++  D  G  L RGT+++LH+K++  E+LE   +++++ K+SQFI +PI L+  K   K V +D E     ++E A  KP
Sbjct:    1 SAQALDKIRYESLTDPSK----------------------LDTGKEL-KIDIIPN--KIDRTLT------FMEALQAGADISMIGQFGVGFYSAYLVAERVTVVTKHNDDEQYVWESSAGGSFTVRPDNDGEPLGRGTKIVLHIKEDQTEYLEERSIKDIVKKHSQFIGYPITLYVEKERNKEVSDDEED----KEEAAPDKP 168

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BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
Match: HSP82 (Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication [Source:SGD;Acc:S000006161])

HSP 1 Score: 201.06 bits (510), Expect = 3.494e-54
Identity = 110/209 (52.63%), Postives = 148/209 (70.81%), Query Frame = 2

Query:  359 AEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDA-STFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
            +E + FQAE+ ++M LIIN++Y NKEIFLRELISNASDALDKIR+ SL++  +     DL+I+I      K + I D+G+GMTK ELI NLGTIAKSGT  F++ LS   +      +IGQFGVGFYS FLVAD+V VISKS+ D QYIWES+A  +F++  D     + RGT + L LKD+ LE+LE   ++ +I ++S+F+ +PI L
Sbjct:    3 SETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVS----MIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQL 207

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BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
Match: HSC82 (Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798])

HSP 1 Score: 199.519 bits (506), Expect = 1.319e-53
Identity = 108/209 (51.67%), Postives = 147/209 (70.33%), Query Frame = 2

Query:  359 AEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDA-STFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
             E + FQAE+ ++M LIIN++Y NKEIFLRELISNASDALDKIR+ +L++  +     DL+I+I      K + I D+G+GMTK ELI NLGTIAKSGT  F++ LS   +      +IGQFGVGFYS FLVAD+V VISK++ D QYIWES+A  +F++  D     + RGT + L LKD+ LE+LE   ++ +I ++S+F+ +PI L
Sbjct:    3 GETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVS----MIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQL 207

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BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Match: EDO45344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT97])

HSP 1 Score: 331.643 bits (849), Expect = 5.628e-97
Identity = 173/269 (64.31%), Postives = 220/269 (81.78%), Query Frame = 2

Query:  206 KDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            K+E +S  K+ ++  KS++ S+TDDE V+REEEAI +DGLNV+Q+KELR+KAEK+ FQAEV+RMMKLIINSLY+NKEIFLRELISN+SDALDKIR +SLT++      ++L IKIKADK    +H+ DTG+GMTK ELIKNLGTIAKSGTS+F QK+ EA ++   ++LIGQFGVGFYSSFLVAD+V V SK++ D QYIWESDAS+FSI  DPRG TL+RGT + LHLK+E  ++LE + +++L+ KYSQFINFPI+LW S    V+E
Sbjct:   25 KEEPESAPKVDDDAGKSRDASRTDDEAVQREEEAIKLDGLNVAQMKELRDKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNSSDALDKIRLMSLTDKTAFDSGDELSIKIKADKENNILHVTDTGIGMTKEELIKNLGTIAKSGTSEFFQKIQEAASSDSASDLIGQFGVGFYSSFLVADRVIVTSKNNDDKQYIWESDASSFSISEDPRGPTLKRGTTISLHLKEEARDYLEPETIKDLVKKYSQFINFPIFLWTSKTTEVEE 293

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BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Match: HSP90 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ66])

HSP 1 Score: 197.978 bits (502), Expect = 1.299e-52
Identity = 108/220 (49.09%), Postives = 153/220 (69.55%), Query Frame = 2

Query:  326 NVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDA-STFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
            N +Q  E  +  E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR++SLT+       +DL I +  +K   ++ I D+GVGMTK +L+ NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KV V +K + D QYIWES A  +F++ RD  G  L RGT+++L+LK++  E+LE   ++ ++ K+SQFI +P+ L
Sbjct:    5 NAAQNMEEDQDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYLSLTDPSVLDSCKDLKITLIPNKEENSLTIQDSGVGMTKADLVNNLGTIAKSGTKTFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVVVTTKHNDDEQYIWESAAGGSFTVKRD-SGEPLGRGTKIVLYLKEDQTEYLEEKRIKEIVKKHSQFIGYPLSL 219

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BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Match: EDO45666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS03])

HSP 1 Score: 160.999 bits (406), Expect = 6.669e-41
Identity = 96/209 (45.93%), Postives = 136/209 (65.07%), Query Frame = 2

Query:  374 FQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKL-SEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQ-----YIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL 982
            FQAE  +++ ++  SLY  KE+F+RE+ISNASDAL+K+R   LT +D +     L I I+ D+ A T  I D GVGMT+ EL+ +LG IAKSG+  F++KL +EA+++ E   +IGQFGVGFYS+F+VADKV V +KS   YQ     Y W SD S          N + RGT+++LHLK++   F     + +++ +YS F+ FPIYL
Sbjct:   15 FQAETKQLLDIVAKSLYSEKEVFIREVISNASDALEKVRHFFLTGKDVSETETSLEIMIETDQEAGTFTIQDNGVGMTEEELMDHLGVIAKSGSKVFMEKLKNEARSSHE--NIIGQFGVGFYSTFMVADKVDVYTKS---YQPNSQGYFWTSDGS--GSYEYAEANGVARGTKLVLHLKEDCKRFAMKTAVEDIVQRYSNFVGFPIYL 216

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BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90b1 (heat shock protein 90 beta family member 1 [Source:NCBI gene;Acc:101166123])

HSP 1 Score: 341.273 bits (874), Expect = 1.910e-100
Identity = 177/269 (65.80%), Postives = 223/269 (82.90%), Query Frame = 2

Query:  209 DEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGE-LNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDE 1012
            DE D +  ++E + KS++ S+TDDEVV+REEEAI +DGLN +QIKELREK+EK+ FQAEV+RMMKLIINSLYKNKEIFLRELISNASDALDKIR +SLT++D    NE+L IKIK+DK    +HI DTG+GMTK ELIKNLGTIAKSGTS+F+ K+SE ++ G+  +ELIGQFGVGFYS+FLVADKV V SK + D Q+IWESD++ FS++ DPRG+TL RGT + L LK+E  +FLE++ ++NL+ KYSQFINFPIY+W S  + V+E
Sbjct:   24 DEVDVDATVEEELGKSRDGSRTDDEVVQREEEAIQLDGLNAAQIKELREKSEKHMFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTHEDALAANEELTIKIKSDKEKNMLHITDTGIGMTKEELIKNLGTIAKSGTSEFLNKMSEMQSEGQSTSELIGQFGVGFYSAFLVADKVIVSSKHNNDTQHIWESDSNQFSVIEDPRGDTLGRGTTITLVLKEEASDFLELETIKNLVRKYSQFINFPIYVWASKTETVEE 292

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BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 204.912 bits (520), Expect = 2.019e-54
Identity = 115/223 (51.57%), Postives = 157/223 (70.40%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW--KSSVKNVD 1009
            + E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L I+++ D  A+T+ I DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QYIWES A     V+   G  + RGT+VILHLK++  E+ E   ++ +I K+SQFI +PI L+  K+  K VD
Sbjct:    9 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEVD 227

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BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 204.912 bits (520), Expect = 2.095e-54
Identity = 115/223 (51.57%), Postives = 157/223 (70.40%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW--KSSVKNVD 1009
            + E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L I+++ D  A+T+ I DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QYIWES A     V+   G  + RGT+VILHLK++  E+ E   ++ +I K+SQFI +PI L+  K+  K VD
Sbjct:    9 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEVD 227

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 204.912 bits (520), Expect = 2.114e-54
Identity = 115/223 (51.57%), Postives = 157/223 (70.40%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW--KSSVKNVD 1009
            + E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L I+++ D  A+T+ I DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QYIWES A     V+   G  + RGT+VILHLK++  E+ E   ++ +I K+SQFI +PI L+  K+  K VD
Sbjct:    9 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEVD 227

[Close]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 202.601 bits (514), Expect = 1.109e-53
Identity = 109/213 (51.17%), Postives = 151/213 (70.89%), Query Frame = 2

Query:  347 LREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLW 985
            + E+ E + FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+  +    ++L I+I  +K  +T+ ++DTG+GMTK +LI NLGTIAKSGT  F++ L    +      +IGQFGVGFYS++LVA+KVTVI+K + D QY WES A     V+      L RGT+VILHLK++  E+LE   ++ ++ K+SQFI +PI L+
Sbjct:    9 MEEETETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPAKLDSGKELKIEITPNKQERTLTLMDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS----MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKLDNSEPLGRGTKVILHLKEDQSEYLEERRIKEIVKKHSQFIGYPITLF 217

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000054819.1 (SMESG000054819.1)

HSP 1 Score: 619.772 bits (1597), Expect = 0.000e+0
Identity = 325/325 (100.00%), Postives = 325/325 (100.00%), Query Frame = 2

Query:   83 MKNLIYLFFIILVFSIAYRCDDETAKQTEQQMKDSTDESKIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDEDHESAVSKRDEDANV 1057
            MKNLIYLFFIILVFSIAYRCDDETAKQTEQQMKDSTDESKIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYIKIKADKAAKTIHILDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDEDHESAVSKRDEDANV
Sbjct:    1 MKNLIYLFFIILVFSIAYRCDDETAKQTEQQMKDSTDESKIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYIKIKADKAAKTIHILDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDEDHESAVSKRDEDANV 325

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000041107.1 (SMESG000041107.1)

HSP 1 Score: 374.015 bits (959), Expect = 2.703e-112
Identity = 204/295 (69.15%), Postives = 247/295 (83.73%), Query Frame = 2

Query:  185 STDESKIKDEADSNLKLKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKSSVKNVDED----HESAVSKRDEDANV 1057
            S  ES++K ++D  +K+ E+I KSK+ SKTDDEVVKREEEAI++DGLNV+Q+KELR+KAEK+ FQAEVD+MMKLIINSLYKNKEIFLRELISNASDALDKIRFISLT+       +DL+IKIKADK  K++HI+DTGVGMTK +LI NLGTIAKSGTSDF++KLS++K+T E+++LIGQFGVGFYSSFLVADKVTVISK + D Q+IWESDA++FS+V DPRGNTL RGTE+ILHLK+E  E+LE D L+NL+ KYSQFINFPIYLW S  + V+E           K+DED  V
Sbjct:   24 SYSESQVKPQSD-EIKIDEDITKSKQGSKTDDEVVKREEEAINLDGLNVAQMKELRDKAEKFAFQAEVDKMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTDSTALDAFKDLHIKIKADKDGKSLHIVDTGVGMTKQDLITNLGTIAKSGTSDFLKKLSDSKSTNEMSDLIGQFGVGFYSSFLVADKVTVISKHNDDKQHIWESDANSFSVVEDPRGNTLLRGTEIILHLKEEAHEYLEADSLKNLVTKYSQFINFPIYLWSSKTETVEEKPIETKNEDTEKKDEDVTV 317

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000068132.1 (SMESG000068132.1)

HSP 1 Score: 313.538 bits (802), Expect = 3.217e-90
Identity = 191/337 (56.68%), Postives = 244/337 (72.40%), Query Frame = 2

Query:   89 NLIYLFFIILVFSIAYRCDDETAKQTEQQMKDSTDESKIKDEA------DSNLKLKENIAKSKEP-SKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYXXXXXXXXXXXXXXLDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDAS-TFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS------SVKNVDEDHESAVSKRDEDANV 1057
            NL+ L  I+ V    +   DE+ +++  Q   +T ESKI  E       D+ +KLK+ +   KEP SKTDDEV++REEEAI +DGL+ +Q+KE+R+KAEK+ FQAEVDRMMKLIINSLY NKEIFLRELISNASDALDKIRFISLT+     +  +L IKIKADK    + I+DTG+GMT+ EL+K LGTIAKSGT++F+ K+ E + T   ++ IGQFGVGFYS +LVAD VTVISK++ D QYIWESD+S TFS+ +DPRGNTL RGTE++L LK    E+LE + LR L+ +YSQ+++FPIYLW S      S+K  +E    A SK DE A V
Sbjct:    6 NLVILV-ILFVLDFEFIHTDESDQESVFQ---ATKESKITPETLDSTIEDNEIKLKKTM---KEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI-EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNE--VKADSKDDESATV 332

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000054821.1 (SMESG000054821.1)

HSP 1 Score: 312.383 bits (799), Expect = 1.858e-86
Identity = 443/456 (97.15%), Postives = 447/456 (98.03%), Query Frame = 2

Query: 1361 TKIEPEVEVKKVYKSRKLHSITEHHVYKPTENXXXXXXXXXXXXXXXXXXXXXXXTQDSDWXXXXXXXXXXXXXXXXXXXXXXXSNGDGIPDCREDSSDNKLKLRFKSRQKRLXXXXXXXXXXXXXXXXXXXXXXILEDSDGNDIPDFLDKNRDVNNKADFEAILADAARQDHXXXXXXXXXXXXXXXXXXXXXXXXSDRXXXXXXXXXXXXXXXXXXXXXXXSNGDGIPDCIMKDSXXXXXXXXXXXXXXXXXXXXLKDPNHPLFNFFMDSXXXXXXXXXXXXXXXXXXXXHRDYDADGDGESDLFPDKDKDGVPXXXXXXXXXXGIPDHMQDRXXXXXXXXXXXXXXXXXXXXXXXXSXXXXXXXXXXXXXXXXXXXXXXXXXSNGDGIIDCRPRDSXXXXXXXXXXXXXXXXXXXXXXXXXSMAFLLYKRTQQMDALPGKKSKIIILMKTVDV 2728
            TKIEPEVEVKKVYKSRKLHSITEHHVYKPTENDHDCDGIPDDEDDDIDNDGLLDHTQDSDWDGDLNHIDEDDDNDGIPDKEDPDSNGDGIPDCREDSSDNKLKLRFKSRQKRLDSDMDGVPDDSDIDDDQDGIPDILEDSDGNDIPDFLDKNRDVNNKADFEAILADAARQDHDCDGIPDQYDPDDDNDGFFDKKQDSDRDGILNEYDDDDDNDGIPDSEDPDSNGDGIPDCIMKDSDGDGIPDHIDTDDDNDGIPDLKDPNHPLFNFFMDSDNDGIPDSMDNDDDNDGIPDHRDYDADGDGESDLFPDKDKDGVPDNIDNDMNNDGIPDHMQDRDCDGIPDLIDPDDDNDGYFDNKQDSDNDGILNEWDDDDDNDGIPDINDPDSNGDGIIDCRPRDSDGDGIPDHLDPDDDNDGIPDYLDPDSMAFLLYKRTQQMDALP  +++       VD+
Sbjct:  115 TKIEPEVEVKKVYKSRKLHSITEHHVYKPTENDHDCDGIPDDEDDDIDNDGLLDHTQDSDWDGDLNHIDEDDDNDGIPDKEDPDSNGDGIPDCREDSSDNKLKLRFKSRQKRLDSDMDGVPDDSDIDDDQDGIPDILEDSDGNDIPDFLDKNRDVNNKADFEAILADAARQDHDCDGIPDQYDPDDDNDGFFDKKQDSDRDGILNEYDDDDDNDGIPDSEDPDSNGDGIPDCIMKDSDGDGIPDHIDTDDDNDGIPDLKDPNHPLFNFFMDSDNDGIPDSMDNDDDNDGIPDHRDYDADGDGESDLFPDKDKDGVPDNIDNDMNNDGIPDHMQDRDCDGIPDLIDPDDDNDGYFDNKQDSDNDGILNEWDDDDDNDGIPDINDPDSNGDGIIDCRPRDSDGDGIPDHLDPDDDNDGIPDYLDPDSMAFLLYKRTQQMDALPASQARHEANTDNVDL 570

HSP 2 Score: 250.366 bits (638), Expect = 6.285e-67
Identity = 225/225 (100.00%), Postives = 225/225 (100.00%), Query Frame = 1

Query: 3673 ARKILDHDCDGIPXXXXXXXXXXXXXXXXXXXXXXGIVNSLDPDDDNDGIVDALDDDANGDGIPDCKAKSKNLRXXXXXXXXXXXXXXXXSRKLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDTAKTSQMHNKVEKNIPTQQTIISKNKAKVVDSKYSQNKIIKNHDTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP 4347
            ARKILDHDCDGIPDGKDKDSDNDGVDDDLQDSDHDGIVNSLDPDDDNDGIVDALDDDANGDGIPDCKAKSKNLRKVISKKSPAKPKVKKISRKLLSVEEDDDEETESGENNDSEEESESDDEEEEEESNNYKSEDEVDTAKTSQMHNKVEKNIPTQQTIISKNKAKVVDSKYSQNKIIKNHDTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP
Sbjct:  825 ARKILDHDCDGIPDGKDKDSDNDGVDDDLQDSDHDGIVNSLDPDDDNDGIVDALDDDANGDGIPDCKAKSKNLRKVISKKSPAKPKVKKISRKLLSVEEDDDEETESGENNDSEEESESDDEEEEEESNNYKSEDEVDTAKTSQMHNKVEKNIPTQQTIISKNKAKVVDSKYSQNKIIKNHDTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP 1049

HSP 3 Score: 182.57 bits (462), Expect = 5.263e-46
Identity = 134/136 (98.53%), Postives = 135/136 (99.26%), Query Frame = 1

Query: 2860 MEASQARHEANTDNVDLGDPGDKXXXXXXXXXXXXXXXXXXXXRTQDSDMDGELNHXXXXXXXXXXXXXXXXXANGDGIPDCRRDDFINYKLIKSRTGKIKRVLRIRKKTEEEENIDHQKKSINIKLIHQQALEIG 3267
            + ASQARHEANTDNVDLGDPGDKDCDGVPDDIDLDIDNDGKIDRTQDSDMDGELNHIDEDDDNDGIPDIEDPDANGDGIPDCRRDDFINYKLIKSRTGKIKRVLRIRKKTEEEENIDHQKKSINIKLIHQQALEIG
Sbjct:  554 LPASQARHEANTDNVDLGDPGDKDCDGVPDDIDLDIDNDGKIDRTQDSDMDGELNHIDEDDDNDGIPDIEDPDANGDGIPDCRRDDFINYKLIKSRTGKIKRVLRIRKKTEEEENIDHQKKSINIKLIHQQALEIG 689

HSP 4 Score: 55.8398 bits (133), Expect = 2.781e-7
Identity = 32/44 (72.73%), Postives = 37/44 (84.09%), Query Frame = 1

Query: 4216 DTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP 4347
            DTE TN   K+S ++ V +NLK+DSDGDGIPDYLEKDSDGDGIP
Sbjct: 1192 DTESTNIK-KESSKNNVLDNLKQDSDGDGIPDYLEKDSDGDGIP 1234

[Close]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Match: SMESG000054821.1 (SMESG000054821.1)

HSP 1 Score: 311.997 bits (798), Expect = 2.977e-86
Identity = 443/456 (97.15%), Postives = 447/456 (98.03%), Query Frame = 2

Query: 1361 TKIEPEVEVKKVYKSRKLHSITEHHVYKPTENXXXXXXXXXXXXXXXXXXXXXXXTQDSDWXXXXXXXXXXXXXXXXXXXXXXXSNGDGIPDCREDSSDNKLKLRFKSRQKRLXXXXXXXXXXXXXXXXXXXXXXILEDSDGNDIPDFLDKNRDVNNKADFEAILADAARQDHXXXXXXXXXXXXXXXXXXXXXXXXSDRXXXXXXXXXXXXXXXXXXXXXXXSNGDGIPDCIMKDSXXXXXXXXXXXXXXXXXXXXLKDPNHPLFNFFMDSXXXXXXXXXXXXXXXXXXXXHRDYDADGDGESDLFPDKDKDGVPXXXXXXXXXXGIPDHMQDRXXXXXXXXXXXXXXXXXXXXXXXXSXXXXXXXXXXXXXXXXXXXXXXXXXSNGDGIIDCRPRDSXXXXXXXXXXXXXXXXXXXXXXXXXSMAFLLYKRTQQMDALPGKKSKIIILMKTVDV 2728
            TKIEPEVEVKKVYKSRKLHSITEHHVYKPTENDHDCDGIPDDEDDDIDNDGLLDHTQDSDWDGDLNHIDEDDDNDGIPDKEDPDSNGDGIPDCREDSSDNKLKLRFKSRQKRLDSDMDGVPDDSDIDDDQDGIPDILEDSDGNDIPDFLDKNRDVNNKADFEAILADAARQDHDCDGIPDQYDPDDDNDGFFDKKQDSDRDGILNEYDDDDDNDGIPDSEDPDSNGDGIPDCIMKDSDGDGIPDHIDTDDDNDGIPDLKDPNHPLFNFFMDSDNDGIPDSMDNDDDNDGIPDHRDYDADGDGESDLFPDKDKDGVPDNIDNDMNNDGIPDHMQDRDCDGIPDLIDPDDDNDGYFDNKQDSDNDGILNEWDDDDDNDGIPDINDPDSNGDGIIDCRPRDSDGDGIPDHLDPDDDNDGIPDYLDPDSMAFLLYKRTQQMDALP  +++       VD+
Sbjct:  133 TKIEPEVEVKKVYKSRKLHSITEHHVYKPTENDHDCDGIPDDEDDDIDNDGLLDHTQDSDWDGDLNHIDEDDDNDGIPDKEDPDSNGDGIPDCREDSSDNKLKLRFKSRQKRLDSDMDGVPDDSDIDDDQDGIPDILEDSDGNDIPDFLDKNRDVNNKADFEAILADAARQDHDCDGIPDQYDPDDDNDGFFDKKQDSDRDGILNEYDDDDDNDGIPDSEDPDSNGDGIPDCIMKDSDGDGIPDHIDTDDDNDGIPDLKDPNHPLFNFFMDSDNDGIPDSMDNDDDNDGIPDHRDYDADGDGESDLFPDKDKDGVPDNIDNDMNNDGIPDHMQDRDCDGIPDLIDPDDDNDGYFDNKQDSDNDGILNEWDDDDDNDGIPDINDPDSNGDGIIDCRPRDSDGDGIPDHLDPDDDNDGIPDYLDPDSMAFLLYKRTQQMDALPASQARHEANTDNVDL 588

HSP 2 Score: 250.751 bits (639), Expect = 5.232e-67
Identity = 225/225 (100.00%), Postives = 225/225 (100.00%), Query Frame = 1

Query: 3673 ARKILDHDCDGIPXXXXXXXXXXXXXXXXXXXXXXGIVNSLDPDDDNDGIVDALDDDANGDGIPDCKAKSKNLRXXXXXXXXXXXXXXXXSRKLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDTAKTSQMHNKVEKNIPTQQTIISKNKAKVVDSKYSQNKIIKNHDTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP 4347
            ARKILDHDCDGIPDGKDKDSDNDGVDDDLQDSDHDGIVNSLDPDDDNDGIVDALDDDANGDGIPDCKAKSKNLRKVISKKSPAKPKVKKISRKLLSVEEDDDEETESGENNDSEEESESDDEEEEEESNNYKSEDEVDTAKTSQMHNKVEKNIPTQQTIISKNKAKVVDSKYSQNKIIKNHDTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP
Sbjct:  843 ARKILDHDCDGIPDGKDKDSDNDGVDDDLQDSDHDGIVNSLDPDDDNDGIVDALDDDANGDGIPDCKAKSKNLRKVISKKSPAKPKVKKISRKLLSVEEDDDEETESGENNDSEEESESDDEEEEEESNNYKSEDEVDTAKTSQMHNKVEKNIPTQQTIISKNKAKVVDSKYSQNKIIKNHDTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP 1067

HSP 3 Score: 182.956 bits (463), Expect = 5.146e-46
Identity = 134/136 (98.53%), Postives = 135/136 (99.26%), Query Frame = 1

Query: 2860 MEASQARHEANTDNVDLGDPGDKXXXXXXXXXXXXXXXXXXXXRTQDSDMDGELNHXXXXXXXXXXXXXXXXXANGDGIPDCRRDDFINYKLIKSRTGKIKRVLRIRKKTEEEENIDHQKKSINIKLIHQQALEIG 3267
            + ASQARHEANTDNVDLGDPGDKDCDGVPDDIDLDIDNDGKIDRTQDSDMDGELNHIDEDDDNDGIPDIEDPDANGDGIPDCRRDDFINYKLIKSRTGKIKRVLRIRKKTEEEENIDHQKKSINIKLIHQQALEIG
Sbjct:  572 LPASQARHEANTDNVDLGDPGDKDCDGVPDDIDLDIDNDGKIDRTQDSDMDGELNHIDEDDDNDGIPDIEDPDANGDGIPDCRRDDFINYKLIKSRTGKIKRVLRIRKKTEEEENIDHQKKSINIKLIHQQALEIG 707

HSP 4 Score: 56.225 bits (134), Expect = 2.476e-7
Identity = 32/44 (72.73%), Postives = 37/44 (84.09%), Query Frame = 1

Query: 4216 DTEKTNKGIKDSKESLVAENLKKDSDGDGIPDYLEKDSDGDGIP 4347
            DTE TN   K+S ++ V +NLK+DSDGDGIPDYLEKDSDGDGIP
Sbjct: 1210 DTESTNIK-KESSKNNVLDNLKQDSDGDGIPDYLEKDSDGDGIP 1252

The following BLAST results are available for this feature:

BLAST of HATPase_c domain-containing protein vs. Ensembl Human
BLAST of HATPase_c domain-containing protein vs. Ensembl Celegans
BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
BLAST of HATPase_c domain-containing protein vs. TrEMBL
BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
BLAST of HATPase_c domain-containing protein vs. Planmine SMEST

BLAST of HATPase_c domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HSP90B1	1.911e-106	66.41	heat shock protein 90 beta family member 1 [Source...	[more]
HSP90B1	1.970e-106	66.41	heat shock protein 90 beta family member 1 [Source...	[more]
HSP90B1	1.500e-99	66.41	heat shock protein 90 beta family member 1 [Source...	[more]
HSP90AA1	3.851e-55	52.13	heat shock protein 90 alpha family class A member ...	[more]
HSP90AA1	1.316e-54	53.08	heat shock protein 90 alpha family class A member ...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
enpl-1	1.241e-84	64.50	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	1.241e-84	64.50	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	2.256e-70	63.50	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	2.256e-70	63.50	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	2.256e-70	63.50	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Gp93	9.378e-90	61.60	gene:FBgn0039562 transcript:FBtr0085254	[more]
Hsp83	7.334e-56	51.89	gene:FBgn0001233 transcript:FBtr0332873	[more]
Hsp83	7.334e-56	51.89	gene:FBgn0001233 transcript:FBtr0073040	[more]
Trap1	1.824e-37	41.86	gene:FBgn0026761 transcript:FBtr0086149	[more]
Trap1	1.824e-37	41.86	gene:FBgn0026761 transcript:FBtr0336666	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	1.617e-97	62.87	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90b1	1.736e-96	64.37	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90aa1.1	2.740e-55	51.12	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90aa1.1	2.740e-55	51.12	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90ab1	9.523e-54	51.46	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	3.941e-97	63.94	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	3.234e-96	63.94	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	5.035e-96	63.94	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	6.730e-96	63.94	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	7.023e-96	63.94	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hsp90b1	5.229e-101	65.43	heat shock protein 90, beta (Grp94), member 1 [Sou...	[more]
Hsp90aa1	1.590e-55	52.13	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90aa1	1.590e-55	52.13	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90aa1	7.735e-55	53.97	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90ab1	1.032e-53	51.94	heat shock protein 90 alpha (cytosolic), class B m...	[more]

BLAST of HATPase_c domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q66HD0\|ENPL_RAT	2.661e-100	64.71	Endoplasmin OS=Rattus norvegicus OX=10116 GN=Hsp90...	[more]
sp\|P08113\|ENPL_MOUSE	3.658e-100	65.43	Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE...	[more]
sp\|Q95M18\|ENPL_BOVIN	1.593e-99	65.54	Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 ...	[more]
sp\|P41148\|ENPL_CANLF	4.879e-99	66.41	Endoplasmin OS=Canis lupus familiaris OX=9615 GN=H...	[more]
sp\|Q29092\|ENPL_PIG	4.975e-99	65.66	Endoplasmin OS=Sus scrofa OX=9823 GN=HSP90B1 PE=2 ...	[more]

BLAST of HATPase_c domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2R4NBU5	1.231e-150	79.46	Heat shock protein 902 OS=Dugesia japonica OX=6161...	[more]
A0A2R4NBU1	4.570e-111	69.70	Heat shock protein 903 OS=Dugesia japonica OX=6161...	[more]
A0A4W2IA49	2.896e-104	65.91	Heat shock protein 90 beta family member 1 OS=Bos ...	[more]
A0A1I8J8H1	4.792e-104	71.48	HATPase_c domain-containing protein OS=Macrostomum...	[more]
G9K4W5	8.179e-104	66.41	Heat shock protein 90kDa beta, member 1 (Fragment)...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	1.487e-96	63.30	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90aa1.2	2.079e-54	50.70	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	2.079e-54	50.70	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	1.137e-53	51.17	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	2.127e-53	51.17	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
hsp90b1	3.972e-77	53.85	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
ENSPMAT00000003399.1	4.443e-40	40.28	pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 ge...	[more]
hsp90ab1	6.713e-27	36.95	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
HSP82	3.494e-54	52.63	Hsp90 chaperone; redundant in function with Hsc82p...	[more]
HSC82	1.319e-53	51.67	Cytoplasmic chaperone of the Hsp90 family; plays a...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO45344	5.628e-97	64.31	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
HSP90	1.299e-52	49.09	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45666	6.669e-41	45.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of HATPase_c domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	1.910e-100	65.80	heat shock protein 90 beta family member 1 [Source...	[more]
hsp90aa1.2	2.019e-54	51.57	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	2.095e-54	51.57	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	2.114e-54	51.57	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	1.109e-53	51.17	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]

BLAST of HATPase_c domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000054819.1	0.000e+0	100.00	SMESG000054819.1	[more]
SMESG000041107.1	2.703e-112	69.15	SMESG000041107.1	[more]
SMESG000068132.1	3.217e-90	56.68	SMESG000068132.1	[more]
SMESG000054821.1	1.858e-86	97.15	SMESG000054821.1	[more]
SMESG000054821.1	2.977e-86	97.15	SMESG000054821.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30016760 ID=SMED30016760|Name=HATPase_c domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4348bp
GCAAATCAAATTTGTACACCATTTTTAACCGATTTTTTCTGGCGGTAAAT
TTAGAATAAATATTTAAATTTTTGGTTTGAGAATGAAAAATCTGATTTAC
TTATTTTTCATCATTCTCGTATTCTCAATTGCTTACCGATGTGACGACGA
AACCGCTAAACAAACTGAACAACAAATGAAAGATTCAACCGATGAATCGA
AAATAAAGGACGAGGCAGATTCCAATCTGAAATTGAAAGAAAACATAGCC
AAATCGAAAGAGCCATCGAAAACCGACGATGAAGTCGTCAAAAGAGAGGA
AGAGGCCATTAGTATAGATGGTTTGAATGTTAGTCAAATAAAAGAACTTC
GCGAAAAAGCGGAAAAATATACTTTCCAAGCCGAGGTTGACAGGATGATG
AAATTGATCATTAACTCCTTATACAAAAATAAAGAAATATTTTTACGTGA
ATTAATTTCAAATGCATCCGATGCGCTTGACAAAATCAGATTCATCTCTT
TGACAAATCAAGACAGAAACTTTGATAATGAGGATTTATACATAAAGATA
AAAGCAGATAAAGCGGCAAAAACTATCCATATTCTTGATACAGGAGTCGG
TATGACTAAAACAGAATTGATCAAGAATCTCGGAACAATAGCTAAATCAG
GAACGTCCGATTTCATTCAGAAACTGTCAGAAGCGAAAAATACCGGAGAA
CTTAATGAACTTATTGGTCAATTCGGAGTCGGATTTTATTCTTCCTTTCT
CGTAGCTGACAAAGTTACCGTTATTTCTAAATCAGACGCCGATTATCAAT
ATATATGGGAATCCGATGCCTCTACATTCTCTATTGTCCGAGATCCAAGA
GGAAACACTTTAGAAAGAGGAACTGAAGTTATTCTTCATTTAAAGGACGA
AGTTCTTGAATTTTTGGAAATAGATGTTCTGAGAAATCTAATTCACAAAT
ACAGTCAATTTATTAATTTTCCTATTTACCTTTGGAAAAGTTCCGTTAAA
AATGTTGATGAAGATCATGAAAGTGCTGTTTCTAAAAGAGATGAAGATGC
TAATGTGAAACCTCTTTCATTGGCAACTTTTCGAAAGCTTTTGCAAATTG
AAGACGACGATGATCTTGAAAGTGAAGAAGAGGAGGAAGAAGATGTAGAT
GAAAAAAAAGAAAATACCGAGGAAGCTGCTGAAGAAACTACAATTGATCC
GTCAGAAGAAGATGAAAATGAGATCGTCGATGAAGACGAAGAGAATAGTG
AACTTGAAGAAGAAAGTCAAGAAGAAGAGGAAAATTCTGATGATGATGAA
ATCGATGAAAGTGATGAAGATAACTCAGAAGAAGAAGAAGCAGAAATGGA
TGATGAAGAAACTAAAATAGAACCAGAGGTCGAAGTAAAAAAGGTTTATA
AAAGTCGAAAACTGCATTCAATTACTGAGCACCATGTTTATAAACCTACG
GAAAATGATCACGATTGCGACGGAATTCCTGACGACGAGGATGATGATAT
AGATAATGATGGCTTATTAGATCACACGCAAGATTCCGACTGGGATGGAG
ACCTCAACCATATTGACGAAGATGATGACAACGACGGCATTCCTGACAAG
GAAGATCCTGATTCTAATGGAGATGGCATTCCAGATTGTCGAGAAGATAG
TTCAGATAATAAATTAAAACTTAGATTCAAAAGTAGACAAAAGCGACTCG
ACAGTGATATGGATGGAGTTCCAGACGACTCTGACATAGATGATGATCAA
GATGGCATTCCAGATATCTTGGAAGACTCGGATGGAAACGACATTCCTGA
TTTTCTTGACAAAAATAGAGATGTCAACAACAAAGCCGATTTTGAAGCGA
TATTGGCAGATGCCGCTCGTCAAGATCACGACTGTGATGGAATTCCTGAT
CAGTACGATCCCGATGACGACAACGACGGATTTTTCGACAAGAAGCAAGA
TAGTGATCGAGATGGGATACTTAATGAATACGATGATGATGATGACAATG
ACGGAATTCCAGACTCAGAAGATCCGGACTCCAATGGCGATGGAATTCCA
GACTGTATAATGAAGGACAGTGATGGAGATGGAATTCCCGACCATATTGA
TACAGATGATGATAATGATGGAATACCAGATTTGAAGGATCCTAATCATC
CATTATTTAACTTTTTCATGGACAGTGATAATGATGGGATTCCAGATAGT
ATGGACAACGATGACGACAATGATGGGATTCCTGACCACCGGGACTATGA
TGCTGATGGAGATGGCGAAAGTGATCTATTTCCAGACAAAGACAAAGATG
GAGTTCCAGACAATATTGACAATGATATGAACAATGACGGCATTCCAGAT
CATATGCAAGATCGAGATTGTGATGGCATCCCTGATTTAATTGATCCCGA
TGATGACAATGACGGCTATTTTGATAATAAACAAGACAGTGATAATGATG
GCATTCTCAATGAATGGGATGATGATGACGACAATGACGGAATTCCAGAT
ATCAATGATCCTGATTCGAACGGTGACGGTATCATTGACTGCCGACCTCG
TGATTCGGACGGGGATGGAATCCCAGATCATCTTGACCCCGACGATGACA
ACGACGGAATACCAGATTATCTAGATCCAGATTCAATGGCTTTCCTTCTC
TACAAAAGAACGCAGCAAATGGATGCTTTACCAGGTAAAAAGTCTAAAAT
AATTATCCTTATGAAGACTGTTGATGTAATGTTTATAAAATTTATTTTTG
ATTCACAGTCGAGACAATTATTCACACGATTCAACACCAGTTGATGCCCA
TCAACATAATGCTTTATCCAAATGGACTTGTCTTACCGGACAAGGATGAG
TTTGTCCCAATGGAAGCATCACAAGCTCGACATGAAGCCAATACTGACAA
TGTTGATCTTGGAGATCCAGGGGACAAAGATTGCGATGGCGTTCCAGATG
ACATAGATTTAGACATAGACAATGATGGTAAAATAGATAGAACTCAAGAT
TCTGATATGGATGGCGAATTGAATCACATAGATGAAGATGACGATAATGA
CGGCATACCTGATATCGAAGATCCTGACGCTAACGGAGACGGAATTCCCG
ACTGTAGGCGCGATGATTTCATAAATTACAAGCTCATTAAGTCTAGAACT
GGGAAAATTAAACGAGTTCTTAGAATACGGAAAAAAACTGAAGAGGAAGA
AAATATTGATCACCAAAAAAAGTCAATTAATATAAAGTTGATCCATCAAC
AAGCACTTGAAATTGGAAAATCAGATAAGCCAATAAAAAAAATTATTAAA
AAGGTTAATGCCAAAGAACTCAAAAAAGCGGAAGAACTAAAAAGAAAAAC
AACTACGCCATTACCGACAACCACAAAATCTCCAAAGATTACTAAAATTG
TGAAGATAACTAAGACTGTAAAACCTAAGGAAGTAACTAAACTGAAAGTA
GAAACAAAAAAGAAAGCTACAACAAAACCTAAAACTACAACAGAAAAGAA
AACTGTTACTCCAATTAAAACTACTAAAGCTCCTATAACTACCATTAAGC
CACCTACTAAAGTAAAGAAAGCAGCTAAACCAAAGAAAACGAAGAAAACT
TCAAAGAAAAATGTACCAAAGAAAAAGAACGTTAAAAAAGAAAAAGAAAA
AAAAACTAAATCTCACAAGAAAGCTAGAAAAATCTTAGATCACGATTGTG
ATGGAATACCTGATGGTAAAGATAAAGACTCTGATAATGATGGGGTAGAT
GATGATCTTCAAGATTCAGACCACGATGGAATAGTAAATAGTTTGGATCC
AGATGATGACAATGATGGAATTGTGGATGCATTAGATGATGATGCAAATG
GCGACGGGATACCTGATTGTAAGGCTAAAAGTAAAAATCTAAGGAAAGTA
ATTTCAAAAAAGTCTCCTGCAAAACCGAAAGTTAAAAAAATTAGTAGAAA
ATTGCTGTCGGTTGAGGAGGATGATGACGAAGAAACTGAGTCAGGAGAAA
ACAATGACTCTGAAGAAGAGTCTGAATCAGATGATGAAGAAGAAGAAGAA
GAATCGAATAATTATAAAAGTGAAGATGAGGTTGACACAGCTAAGACGTC
TCAAATGCATAATAAAGTGGAGAAAAATATACCAACTCAACAAACAATTA
TCAGCAAAAATAAGGCAAAAGTCGTTGATTCAAAATATTCTCAGAATAAA
ATTATTAAAAATCACGACACTGAAAAGACAAATAAAGGAATAAAAGATTC
CAAAGAAAGTTTAGTTGCTGAAAATCTTAAAAAAGACTCTGATGGTGATG
GAATACCAGATTATCTTGAGAAGGATTCTGATGGAGATGGTATACCAG

protein sequence of SMED30016760-orf-1

>SMED30016760-orf-1 ID=SMED30016760-orf-1|Name=SMED30016760-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=904bp
MKNLIYLFFIILVFSIAYRCDDETAKQTEQQMKDSTDESKIKDEADSNLK
LKENIAKSKEPSKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQA
EVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNE
DLYIKIKADKAAKTIHILDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSE
AKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFS
IVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYL
WKSSVKNVDEDHESAVSKRDEDANVKPLSLATFRKLLQIEDDDDLESEEE
EEEDVDEKKENTEEAAEETTIDPSEEDENEIVDEDEENSELEEESQEEEE
NSDDDEIDESDEDNSEEEEAEMDDEETKIEPEVEVKKVYKSRKLHSITEH
HVYKPTENDHDCDGIPDDEDDDIDNDGLLDHTQDSDWDGDLNHIDEDDDN
DGIPDKEDPDSNGDGIPDCREDSSDNKLKLRFKSRQKRLDSDMDGVPDDS
DIDDDQDGIPDILEDSDGNDIPDFLDKNRDVNNKADFEAILADAARQDHD
CDGIPDQYDPDDDNDGFFDKKQDSDRDGILNEYDDDDDNDGIPDSEDPDS
NGDGIPDCIMKDSDGDGIPDHIDTDDDNDGIPDLKDPNHPLFNFFMDSDN
DGIPDSMDNDDDNDGIPDHRDYDADGDGESDLFPDKDKDGVPDNIDNDMN
NDGIPDHMQDRDCDGIPDLIDPDDDNDGYFDNKQDSDNDGILNEWDDDDD
NDGIPDINDPDSNGDGIIDCRPRDSDGDGIPDHLDPDDDNDGIPDYLDPD
SMAFLLYKRTQQMDALPGKKSKIIILMKTVDVMFIKFIFDSQSRQLFTRF
NTS*

protein sequence of SMED30016760-orf-2

>SMED30016760-orf-2 ID=SMED30016760-orf-2|Name=SMED30016760-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=518bp
MPINIMLYPNGLVLPDKDEFVPMEASQARHEANTDNVDLGDPGDKDCDGV
PDDIDLDIDNDGKIDRTQDSDMDGELNHIDEDDDNDGIPDIEDPDANGDG
IPDCRRDDFINYKLIKSRTGKIKRVLRIRKKTEEEENIDHQKKSINIKLI
HQQALEIGKSDKPIKKIIKKVNAKELKKAEELKRKTTTPLPTTTKSPKIT
KIVKITKTVKPKEVTKLKVETKKKATTKPKTTTEKKTVTPIKTTKAPITT
IKPPTKVKKAAKPKKTKKTSKKNVPKKKNVKKEKEKKTKSHKKARKILDH
DCDGIPDGKDKDSDNDGVDDDLQDSDHDGIVNSLDPDDDNDGIVDALDDD
ANGDGIPDCKAKSKNLRKVISKKSPAKPKVKKISRKLLSVEEDDDEETES
GENNDSEEESESDDEEEEEESNNYKSEDEVDTAKTSQMHNKVEKNIPTQQ
TIISKNKAKVVDSKYSQNKIIKNHDTEKTNKGIKDSKESLVAENLKKDSD
GDGIPDYLEKDSDGDGIP

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000418	head
PLANA:0000428	musculature system
PLANA:0000478	pharynx musculature
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR028974	TSP_type-3_rpt
IPR020575	Hsp90_N
IPR001404	Hsp90_fam
IPR003594	HATPase_C
IPR019805	Heat_shock_protein_90_CS

Vocabulary: **molecular function**
Term	Definition
GO:0005509	calcium ion binding
GO:0005524	ATP binding
GO:0051082	unfolded protein binding
GO:0000166	nucleotide binding

Vocabulary: **biological process**
Term	Definition
GO:0006457	protein folding
GO:0006950	response to stress
GO:0030433	ubiquitin-dependent ERAD pathway

Vocabulary: **cellular component**
Term	Definition
GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen
GO:0016529	sarcoplasmic reticulum
GO:0042470	melanosome

Main menu

HATPase_c domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 31

Owlery

blazegraph-runner