Cytochrome P450 2W1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30016752 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Cytochrome P450 2W1 vs. Ensembl Human
Match: CYP2U1 (cytochrome P450 family 2 subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:20582]) HSP 1 Score: 125.946 bits (315), Expect = 5.229e-30 Identity = 118/460 (25.65%), Postives = 212/460 (46.09%), Query Frame = 2
Query: 422 MHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRN------PGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNV-NILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNF-----SDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
+ ++YG+I+SF I + VVL EA S RP L V+K +GV+ + G +W RK + L E I E K + + ++ P SI ++ + + II + F D+ + + KK + + ++I +S + N P L Y + + ++ ++ + L ++ K+ +E+ + + YL + EEE ++ ++ +F + D+ AG+DT +L WC L ++ +Q K+ EI + S +DK+Q+PY + I EV R ++P + H +N + GY + + +IL + ++ + + IW + F +RF++++ + IK +E F PFG GKR C+GE LA+ E+ L V+L+ + L +SK + +L G GL AP N+ SR
Sbjct: 110 LARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSN-----IICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNIC------PWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDREN--PQDFIDMYLLHM------EEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAP--SLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIK--KETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSK---KPLLTGRFGLTLAPHPFNITISR 543
BLAST of Cytochrome P450 2W1 vs. Ensembl Human
Match: CYP2J2 (cytochrome P450 family 2 subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:2634]) HSP 1 Score: 117.472 bits (293), Expect = 2.418e-27 Identity = 116/450 (25.78%), Postives = 190/450 (42.22%), Query Frame = 2
Query: 428 KIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNL-FHSMTLTIIFKIVFNINTDFDD---EKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKE---------SKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMK-NLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNL 1735
K YGN++S + + V++ L EA H RP+T + +++ K+ G++ S GQ W R+ T AL + E+ I E + L I G + ++ II I F ++ D +++ K + V + +S VFP I K + L WK+ K + N E+ + YLK +++K ++ N I + D+ AG++T + TL W L +A +IQ K+++EI+ + S + + +PY + I EV R IIP V R + + GY L + +IL + + + W D F D F+EN + K + E F PF GKR C+GE LAR E+ + +L+ + N KL+ L G+ +P H L
Sbjct: 73 KKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPW---------------IMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLK--EMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQP--STAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKR---EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLS----LKFRMGITISPVSHRL 496
BLAST of Cytochrome P450 2W1 vs. Ensembl Human
Match: CYP2E1 (cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]) HSP 1 Score: 112.464 bits (280), Expect = 1.124e-25 Identity = 109/445 (24.49%), Postives = 211/445 (47.42%), Query Frame = 2
Query: 377 NLFRIK-SNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKR-RGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNI---LTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEH--QHLNDMNFIR-NFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESK 1669
NLF+++ N K F + + +G +++ + +QR VV+ + EA SGR +L + + R RG++ ++G W R+ + L +G E I LL + + G + L +I I+F + D++DEK + + +N ++++ L N N P + +P R K + N + ++E KE ++ + N L L ++ +E+H + L M+ I +D+ AG++T + TL + L+L +I+ KL EI+ + + + D+ ++PY+ + + E+ R+ T++P + H ++ IF GY + + +++ + ++ +P+ +KF + F+ N+ K K+ + F PF TGKR C GE LAR E+ L L A++ H+ ++ + K
Sbjct: 44 NLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGR--GDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYN------NFPSFLHYLPGSHR--KVIKNVAEVKEYVSERVKEHHQSLDPNCPRD-------LTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIP--AIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFL-NENGKFKY-SDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPK 467
BLAST of Cytochrome P450 2W1 vs. Ensembl Human
Match: CYP2E1 (cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]) HSP 1 Score: 112.464 bits (280), Expect = 1.124e-25 Identity = 109/445 (24.49%), Postives = 211/445 (47.42%), Query Frame = 2
Query: 377 NLFRIK-SNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKR-RGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNI---LTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEH--QHLNDMNFIR-NFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESK 1669
NLF+++ N K F + + +G +++ + +QR VV+ + EA SGR +L + + R RG++ ++G W R+ + L +G E I LL + + G + L +I I+F + D++DEK + + +N ++++ L N N P + +P R K + N + ++E KE ++ + N L L ++ +E+H + L M+ I +D+ AG++T + TL + L+L +I+ KL EI+ + + + D+ ++PY+ + + E+ R+ T++P + H ++ IF GY + + +++ + ++ +P+ +KF + F+ N+ K K+ + F PF TGKR C GE LAR E+ L L A++ H+ ++ + K
Sbjct: 44 NLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGR--GDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYN------NFPSFLHYLPGSHR--KVIKNVAEVKEYVSERVKEHHQSLDPNCPRD-------LTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIP--AIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFL-NENGKFKY-SDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPK 467
BLAST of Cytochrome P450 2W1 vs. Ensembl Human
Match: CYP2W1 (cytochrome P450 family 2 subfamily W member 1 [Source:HGNC Symbol;Acc:HGNC:20243]) HSP 1 Score: 111.309 bits (277), Expect = 2.770e-25 Identity = 102/429 (23.78%), Postives = 185/429 (43.12%), Query Frame = 2
Query: 377 NLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDE---KIKKYIKNVQI-ITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKEN-CETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKI 1648
+L R+ S +++ ME+ + YG +++ + Q+ VVL E EA G L+ RP +++ + + G+ S G W R+ T +ALH + D I + +K L +D G L I F ++F D+ D + I V + + S L N V+P LL+ P + +I++ IL L + + + C + + S Y+ L ++ + N + D+V AG++T +ATL W LL+ +Q +++ E++ + D+ LPY + + EV R+ T++P + G+ L + ++ + + W +F F++ +K +E F PF G+R C+GE LAR E+ L L+ Y++
Sbjct: 45 HLLRL-SQQDRSLMELSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYRGRPFPLALLGWAPSNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQLFN-VYPWLGA-LLQLHRPVLRKIEEVR----AILRTLLEARRPHVCPGDPVCS------YVDALIQQGQGDDPEGLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTP--RLEDQQALPYTSAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVK--REAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRL 456
BLAST of Cytochrome P450 2W1 vs. Ensembl Celegans
Match: cyp-33C2 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O44706]) HSP 1 Score: 110.538 bits (275), Expect = 1.528e-25 Identity = 106/472 (22.46%), Postives = 215/472 (45.55%), Query Frame = 2
Query: 368 LFKNLFRIKSNENKF--FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGR---PLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNA-VFPLTNVPLLKYCVPSVL---RIKKAMDNNVNILTELWKESKENCETNEL--ESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAP--FCHNLK 1738
+F NL I + + F K YG+I++F I N ++++ + E + T + + P +L++ G++ S+G W +R+ + + ++ I ++ + +D GS +F ++ +++F F K +Y + +II + F +F N+P++ +P + K D + + ++ + N+L ES+ E +LK+ Q + E + + +++ D+ AG +T T+ W + ++Q+K+ E+++ + +I + +DK+ LPY +FI E R I+P + H ++ + +G+K+ + ++ T +N +++P+ F DRF++ + K+K ++E PF GKR+C GE LAR E+ L + + YKI + E + ++ NG + AP F LK
Sbjct: 34 VFGNLLSIANPPPGYEAFERWTKKYGDIYTFWIGNTPHIMINTWDKIKETYIRDAETYTNKVRLPALDLFR--GGEYGIIDSNGATWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDIPEVFDHAVANVVNQLLFGYR--FVGPKESEYQELKRIIEAPTDLFGKPHMFLAMNIPVIAKLMPEFMYEGPFKDFRDTAFAFFNKQIEAHRQEVDLNDLNSESTDFVETFLKE-QKRRESEGDSETFSNVQLSNVCMDLWFAGLNTTTNTITWAISYILHHPEVQDKVHEEMDKVIGSDRLI--TTADKNDLPYFNAFINEAQRGINIVPLNLQHATTRDTVINGFKIPKGTGVVAQISTVMNNEEVFPDPHTFNPDRFID-EHGKLKRVEE-LAPFSVGKRSCPGEGLARMELFLFIANFLNRYKIYPSKEGPPS----MDKSNGALIAPRLFSATLK 492
BLAST of Cytochrome P450 2W1 vs. Ensembl Celegans
Match: cyp-33D1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O45659]) HSP 1 Score: 109.768 bits (273), Expect = 2.938e-25 Identity = 106/440 (24.09%), Postives = 202/440 (45.91%), Query Frame = 2
Query: 368 LFKNLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRR-GVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG------SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTN--VPLLKYCVPSVLRIKKAMDNNVNIL-TELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIP-RTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIEL 1654
L NL +++ F + K +G +++F + ++ ++ + + E+ E F G T + + L ++ K +R GVL ++G++W +R+ T L ++ ++ I I+ I+ + G S+ + + + LT+ F F N + +K I ++ + S F + P ++ +P P++ K M +++ + +E ++ + + +ES E YLK+ Q + + +H+ + D+ AG T TL W +Q K+R E++ + +I + +DK+ LPYL +FI E R IIP +H ++ + GY + + ++ T + I+P+A F RF+EN K+K + E PF GKR C+GE LAR E+ L + Y ++L
Sbjct: 34 LVGNLLQLQKFGYDIFHKWKKEFGPVFTFWLADRPFIFITSYEVMKETFVKDGDTFADKQLNQIDKKKLQRNYGVLDTNGEMWREHRRFTLSQLRDLGLGKDLMQEKILLEIEEQFKDINSHLGEEIDLPSVLDRGVGNVINLTL-FNKRFETNQRDEFTYLKSLIDGLRDVASEFRYFIQFLVPWSSKIIP-----GPTLGDKTKGMKEELDVFFVKQVEEHRKEIDFDTVESYDYVEAYLKE-QKKREADGDHETFCNKQLYAMCFDLWMAGLQTTTVTLTWGFSFYLHNADVQLKIREELDRVIGNDRLI--TTADKNCLPYLTAFINETQRCANIIPFNLLHVATRDTVIEGYPVKKGTGVIAQIGTVMSDEQIFPDAHCFNPGRFIENG--KLKKVDE-VIPFSIGKRQCLGEGLARMELFLFFANIFNRYDVQL 461
BLAST of Cytochrome P450 2W1 vs. Ensembl Celegans
Match: cyp-33D3 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:G5EE22]) HSP 1 Score: 104.76 bits (260), Expect = 1.355e-23 Identity = 104/419 (24.82%), Postives = 185/419 (44.15%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYK-YVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFD--DE--KIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIP-RTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKI 1648
F K YG I++F + N+ +V++ + E E F G T + LT K + + GVL ++G +W +R+ T L ++ ++ I ++ L +D + G I L +I +FN D D DE +K I ++ +TS + P T+ L + +R K+ ++ E + + + E+ E YLK+ Q + + + + + D+ AG T T+ W ++Q K+R E+++ + +I S +DK+ LPYL +F+ E R IIP +H ++ + G+ + + ++ T ++ ++P KF +RF+EN K K + E PF GKR C+GE LAR E+ L + Y +
Sbjct: 51 FSNWKKEYGPIFTFWMANKPFVIIASYEKMKETFVKDGDTYVDKQLTHTEKERLGENYGVLDTNGHMWKEHRRFTLTQLRDLGLGKDLMQEKILMEVEELFKELDAHGGEEIDLPKLIDRSVGNVINLTLFNKRFDMDKRDEFAHLKSLIDGMRNVTSQFRYLIQYLVPWTSTVLPGPTLSEKVRAKREELDD--FFYSQIDEHRNEIDFDNTENLDFVEAYLKE-QKKREEDGDFKTFCNKQLCAMLFDLWIAGLMTTTMTMTWGLSYYLYNPEVQRKIREELDKVIGNDRLI--STADKNDLPYLQAFVTETQRTANIIPLNLIHMTTRDTVIDGFPIQKGTGVIAQISTVMYDEKVFPEPYKFKPERFIENG--KFKKVDE-VIPFSIGKRQCLGEGLARIELFLFFANIFNRYDV 461
BLAST of Cytochrome P450 2W1 vs. Ensembl Celegans
Match: cyp-33C1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O44704]) HSP 1 Score: 103.219 bits (256), Expect = 4.693e-23 Identity = 107/464 (23.06%), Postives = 208/464 (44.83%), Query Frame = 2
Query: 368 LFKNLFRIKSNEN--KFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGR---PLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNA-VFPLTNVPLLKYCVPSVL---RIKKAMDNNVNILTELWKESKENCETNEL--ESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAP 1720
+F NL I + K F K YG++++F I N ++++ + E F T + + P+ L + G++ S+G +W +R+ + + ++ I ++ + +D GS +F ++ +++F F K +Y + II S F +F N+P+ +P L IK D + + + + + +L ES+ E +LK+ Q + E + + +++ + D+ AG +T T+ W + ++Q+K+ E+++ + +I + +DK+ LPY + I E R I+P + H ++ + G+K+ + ++ T +N +++P+ F DRF++ + K+K + E PF GKR+C GE LAR E+ L + + YKI + SK + G +G V AP
Sbjct: 34 VFGNLLSIANPPPGYKAFERWTKKYGDVYTFWIGNTPHIMINTWDKIKETFIRDADTYTNKVVLPMVTLSR--GGEYGIIDSNGAMWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDVPEVFDHAVANVVNQLLFGYR--FMGPKENEYQELKHIIDSPAEIFGKLHIFLAMNIPIFAKLLPESLYEGPIKTFRDTTLAFFNKQIEAHRHRIDFEDLNSESTDFVETFLKE-QKRRESEGDSETYSNIQLLNVCIDLWFAGLNTTTNTITWAISYVLHHPEVQDKIHEELDKVIGSDRLI--TTADKNDLPYFNASINESQRGINILPLNLQHATTRDTVIDGFKIPKGTGVVAQISTVMNNEEVFPDPYTFNPDRFID-ENGKLKKVDE-LAPFSVGKRSCPGEGLARMELFLFIANFLNRYKI---HPSKEGLPSMAKG-SGPVVAP 484
BLAST of Cytochrome P450 2W1 vs. Ensembl Celegans
Match: cyp-33C3 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O16670]) HSP 1 Score: 100.523 bits (249), Expect = 3.231e-22 Identity = 96/425 (22.59%), Postives = 186/425 (43.76%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGR-PLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-----SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNES 1666
F K YG++++F + YV++ + +L + F G T + P K G++ S+G +W +R+ L + + I ++ + D G S+ +N ++ IF F + + D +K+++ ++ + ++ + A P L + +L ++ DN + + ++ + + ES E YLK+ Q + E + ++ D+ AG T T+ W + + ++ K+RSE++E V F + +DK+ LPY+ + I EV R ++P V H ++ + +GY + + ++ T + ++P+ KF DRF++ + IK E PF G+R C GE LAR E+ L + HY+I ++E
Sbjct: 51 FRNWTKKYGDVYTFWMGKTPYVMISSYDLLKDTFVRDGDTYKDKYPQPFNQKIRGGNYGIVESNGHLWNTHRRFALTTLRDFGLGKDLMHEKILIEVENIFKKFDAQLGLEQDVSVVMNNAIANVINQNIFGYRFEGDKEEDFKKLRELMEYQETAFATFKVYVEAFIPKVGALLPGRSLDVLL--EEWRDNFYSFFDTQIENHRKKIDFDSQESLDYAEAYLKE-QRKQEALGEFELFSNKQLSNTCLDLWSAGLSTTYTTVTWALAYVLNSPEVLEKMRSELDEVVGKDR--FVTTADKNDLPYMNAAINEVQRCANLLPVNVAHATTRDTVINGYAIKKGTGVIAQISTVMLDEKVFPDPYKFNPDRFIDEHGKLIK--VEQLIPFSIGRRQCPGEGLARMEIFLFVANFFNHYQISPSSEG 468
BLAST of Cytochrome P450 2W1 vs. Ensembl Fly
Match: Cyp18a1 (gene:FBgn0010383 transcript:FBtr0074610) HSP 1 Score: 96.2857 bits (238), Expect = 1.228e-20 Identity = 102/470 (21.70%), Postives = 208/470 (44.26%), Query Frame = 2
Query: 380 LFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIW-----VLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG---------SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKE----SKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMN----FIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIP-RTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAP 1720
L + S ++ FME+ K YG+++S R+ +Q VV+ ++ E F+ T GRP T + ++ G+++S G++W L+ KL + + + + + I + + ++ + G S+ SN+ S+ ++ F I DD K +++ + + + + +P ++ C PS+ K + N + +++ K + + N + + +FYL +++ K + + + N ++ D+ AG +T+ TL W + + K +++ E+++ V + + D LP S I E R +I+P T H P +++ +GY + ++ + + + ++W ++F RF++ E K++ E F PFG G+R C+G+ LAR E+ L + + + I L L L G G P
Sbjct: 66 LLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFT--GRPDTPFMQTLNGY-GIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSI--------DDPKFRRF----NFLIEEGMRLFGEIHTVDYIPTMQ-CFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRD--LVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLP--TIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDT-EGKVRK-PEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPL---PSLKGNVGATITP 510
BLAST of Cytochrome P450 2W1 vs. Ensembl Fly
Match: Cyp18a1 (gene:FBgn0010383 transcript:FBtr0074609) HSP 1 Score: 96.2857 bits (238), Expect = 1.228e-20 Identity = 102/470 (21.70%), Postives = 208/470 (44.26%), Query Frame = 2
Query: 380 LFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIW-----VLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG---------SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKE----SKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMN----FIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIP-RTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAP 1720
L + S ++ FME+ K YG+++S R+ +Q VV+ ++ E F+ T GRP T + ++ G+++S G++W L+ KL + + + + + I + + ++ + G S+ SN+ S+ ++ F I DD K +++ + + + + +P ++ C PS+ K + N + +++ K + + N + + +FYL +++ K + + + N ++ D+ AG +T+ TL W + + K +++ E+++ V + + D LP S I E R +I+P T H P +++ +GY + ++ + + + ++W ++F RF++ E K++ E F PFG G+R C+G+ LAR E+ L + + + I L L L G G P
Sbjct: 66 LLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFT--GRPDTPFMQTLNGY-GIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSI--------DDPKFRRF----NFLIEEGMRLFGEIHTVDYIPTMQ-CFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRD--LVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLP--TIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDT-EGKVRK-PEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPL---PSLKGNVGATITP 510
BLAST of Cytochrome P450 2W1 vs. Ensembl Fly
Match: Cyp305a1 (gene:FBgn0036910 transcript:FBtr0074925) HSP 1 Score: 87.8113 bits (216), Expect = 6.134e-18 Identity = 84/375 (22.40%), Postives = 161/375 (42.93%), Query Frame = 2
Query: 563 KYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNP-GSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELW--------KESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSY-SDKSQLPYLCSFIEEVHRYFTIIPRT-VHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIEL 1654
+ + R+G+ +DGQ+W +R K + + + E I + LL ++R I L +++ ++ ++ + + ++ S + L P L++ P R + +N TEL+ + ++ + S + YL++++ + E N+ + D AGS T + T+ ++LA R +Q KL S++ V S F + S + Y+ +FI EV R+F I P T R + GY + +N IL + + + + W + +F +RF+++ + K E F PFG G+R C+G++LAR + LV ++ H+ + L
Sbjct: 110 RTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGL--LAQFPWLRHVAPD--RTGYNLIQQLN--TELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMK-DRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFK--DEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVL 475
BLAST of Cytochrome P450 2W1 vs. Ensembl Fly
Match: Cyp303a1 (gene:FBgn0001992 transcript:FBtr0343812) HSP 1 Score: 77.0258 bits (188), Expect = 1.605e-14 Identity = 93/392 (23.72%), Postives = 178/392 (45.41%), Query Frame = 2
Query: 533 LSGRPLTELYKY--VSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVI-TENIKLLLNYIDR--NPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITS---------SNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCET--NELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTI----IPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKI 1648
+ GRP Y+ + R GVL +DG++WV R+ + L G D++ E LL + D+ G +T H +T V+ +NT + ++Y IT N+ A+F ++ PLL++ P+ ++++ ++ T + KE + + T N E + + YL+ +E +D + + D+ AGS+T +L +C + L + +IQ + EI E V ++ + +S D+++LPY + E R F + IP HR + + GY++ ++ +++ N +P+ + F DR++ + K L E F PFG G+ C+G+ L R+ + + ++ ++K+
Sbjct: 98 IDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLT------SVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALF--SHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRA---QDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWS-RDRTKLPYCEAITLEAVRMFMLHTFGIP---HRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDGHLK---LPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471
BLAST of Cytochrome P450 2W1 vs. Ensembl Fly
Match: Cyp303a1 (gene:FBgn0001992 transcript:FBtr0080828) HSP 1 Score: 77.0258 bits (188), Expect = 1.605e-14 Identity = 93/392 (23.72%), Postives = 178/392 (45.41%), Query Frame = 2
Query: 533 LSGRPLTELYKY--VSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVI-TENIKLLLNYIDR--NPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITS---------SNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCET--NELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTI----IPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKI 1648
+ GRP Y+ + R GVL +DG++WV R+ + L G D++ E LL + D+ G +T H +T V+ +NT + ++Y IT N+ A+F ++ PLL++ P+ ++++ ++ T + KE + + T N E + + YL+ +E +D + + D+ AGS+T +L +C + L + +IQ + EI E V ++ + +S D+++LPY + E R F + IP HR + + GY++ ++ +++ N +P+ + F DR++ + K L E F PFG G+ C+G+ L R+ + + ++ ++K+
Sbjct: 98 IDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLT------SVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALF--SHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRA---QDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWS-RDRTKLPYCEAITLEAVRMFMLHTFGIP---HRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDGHLK---LPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471
BLAST of Cytochrome P450 2W1 vs. Ensembl Zebrafish
Match: cyp2x7 (cytochrome P450, family 2, subfamily X, polypeptide 7 [Source:ZFIN;Acc:ZDB-GENE-110114-2]) HSP 1 Score: 124.02 bits (310), Expect = 8.850e-30 Identity = 114/438 (26.03%), Postives = 207/438 (47.26%), Query Frame = 2
Query: 368 LFKNLFRIKS-NENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLT--NVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNEL--ESSSIGEFYLKQLQLTK----VYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYK 1645
+F NL +I + K F + + YGNI+S ++ V L E+ EA SGRP + +++ +GV+ +D G +W +R+ L + E+ I I +++++D+N G ++ +FH++ +I ++F D+++E ++ YI+ + + NL N + + PLL+ +P L KKA DN V I+ + ++ + ++ + + + YL +L K + E+ I N D+ AG+DT + TL L L + ++Q K + EI++ +E K + +Y D+ +PY + I EV R I+P +V H ++ GY + + +I+ + W +F F+ + + K E F PF TG R C+GE LAR E+ L V L+ ++
Sbjct: 36 IFGNLLQINMVDPLKEFERLAEKYGNIFSLYTGSKPAVFLNNFEVIKEALVTKAQDFSGRPQDLMISHLTGNKGVVLADYGPLWKDHRRFALMTLRNFGLGKQSMEERILGEISHIVDFLDKNTGKTVDPQIMFHNIASNVINLVLFGCRFDYNNEFLRGYIQRI----AENLRILNGPWNMIYDTFPLLR-ILP--LPFKKAFDN-VKIIKSMNRKLIDEHKSTRVPGQPRDFIDCYLDELDKVKNCVSTFSEDQ-------LIMNIMDMSFAGTDTTSNTLLAAFLYLMNHPEVQVKCQQEIDDVLEGKDQV--TYEDRHNMPYTLAVIHEVQRVANIVPLSVLHCTTRDTELMGYSIPKGTVIIPNLTVVLKEEGQWKFPHEFNPANFLNEQGQFEK--PEAFIPFSTGPRVCLGEGLARMELFLIFVTLLRRFQ 454
BLAST of Cytochrome P450 2W1 vs. Ensembl Zebrafish
Match: cyp2x7 (cytochrome P450, family 2, subfamily X, polypeptide 7 [Source:ZFIN;Acc:ZDB-GENE-110114-2]) HSP 1 Score: 123.635 bits (309), Expect = 1.205e-29 Identity = 114/438 (26.03%), Postives = 206/438 (47.03%), Query Frame = 2
Query: 368 LFKNLFRIKS-NENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLT--NVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNEL--ESSSIGEFYLKQLQLTK----VYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYK 1645
+F NL +I + K F + + YGNI+S ++ V L E+ EA SGRP + +++ +GV+ +D G +W +R+ L + E+ I I +++++D+N G ++ +FH++ +I ++F D+++E ++ YI+ + + NL N + + PLL+ +P L KKA DN V I+ + ++ + ++ + + + YL +L K + E+ I N D+ AG+DT + TL L L + +Q K + EI++ +E K + +Y D+ +PY + I EV R I+P +V H ++ GY + + +I+ + W +F F+ + + K E F PF TG R C+GE LAR E+ L V L+ ++
Sbjct: 36 IFGNLLQINMVDPLKEFERLAEKYGNIFSLYTGSKPAVFLNNFEVIKEALVTKAQDFSGRPQDLMISHLTGNKGVVLADYGPLWKDHRRFALMTLRNFGLGKQSMEERILGEISHIVDFLDKNTGKTVDPQIMFHNIASNVINLVLFGCRFDYNNEFLRGYIQRI----AENLRILNGPWNMIYDTFPLLR-ILP--LPFKKAFDN-VKIIKSMNRKLIDEHKSTRVPGQPRDFIDCYLDELDKVKNCVSTFSEDQ-------LIMNIMDMSFAGTDTTSNTLLAAFLYLMNHPDVQVKCQQEIDDVLEGKDQV--TYEDRHNMPYTLAVIHEVQRVANIVPLSVLHCTTRDTELMGYSIPKGTVIIPNLTVVLKEEGQWKFPHEFNPANFLNEQGQFEK--PEAFIPFSTGPRVCLGEGLARMELFLIFVTLLRRFQ 454
BLAST of Cytochrome P450 2W1 vs. Ensembl Zebrafish
Match: cyp2x9 (cytochrome P450, family 2, subfamily X, polypeptide 9 [Source:ZFIN;Acc:ZDB-GENE-061027-109]) HSP 1 Score: 121.324 bits (303), Expect = 8.032e-29 Identity = 115/442 (26.02%), Postives = 195/442 (44.12%), Query Frame = 2
Query: 368 LFKNLFRIK-SNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLT--NVPLLKYCVPSVLRIKKAMDNNVN---ILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNES 1666
LF NL + +N K F + YGNI+S ++ +VVL E EA + +GRP + V+K GV+ SD G W +R+ L + E+ I + +++ +++ G + +FH+ II ++F D+DDE +K +I + + N +N + + P+ +Y L +KA N + T+L KE K+ E + YL +L + ++ I D+ AG+DT + TL L L ++Q K + EI++ +E K SY D+ +PY + I EV R +P +V H K+ GY + + ++ + ++ W +F F+ + E K E F PF G R C+GE LAR E+ L +V L+ ++ N++
Sbjct: 36 LFGNLLELNINNPLKDFERLANRYGNIYSLYFGSKPWVVLNGFEALKEALVTKAVDFAGRPQDLMVNRVTKGGGVILSDYGPSWKEHRRFALMTLRNFGLGKQSMEERILGEVSHIIDKLEKRVGTAFDPQTMFHNAASNIICIVLFGSRYDYDDEFLKLFIH----LYTENAKIANGPWAMIYDTFPMFRYLP---LPFRKAFANASKARELSTQLVKEHKKTWVPGE--PRDFIDCYLDELDKRG---NDGSSFSEAQLILYVLDLHFAGTDTTSNTLLTGFLYLMTHPEVQAKCQQEIDDVLEDKDQA--SYEDRHSMPYTQAVIHEVQRVANTVPLSVFHCTTKDTELMGYNIPKGTFVIPNLGSALKEEGQWKFPHEFNPANFLNEQGEFEK--PEAFVPFSAGPRVCLGEGLARMELFLVMVTLLRRFQFVWPNDA 461
BLAST of Cytochrome P450 2W1 vs. Ensembl Zebrafish
Match: cyp2x9 (cytochrome P450, family 2, subfamily X, polypeptide 9 [Source:ZFIN;Acc:ZDB-GENE-061027-109]) HSP 1 Score: 121.324 bits (303), Expect = 8.032e-29 Identity = 115/442 (26.02%), Postives = 195/442 (44.12%), Query Frame = 2
Query: 368 LFKNLFRIK-SNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLT--NVPLLKYCVPSVLRIKKAMDNNVN---ILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNES 1666
LF NL + +N K F + YGNI+S ++ +VVL E EA + +GRP + V+K GV+ SD G W +R+ L + E+ I + +++ +++ G + +FH+ II ++F D+DDE +K +I + + N +N + + P+ +Y L +KA N + T+L KE K+ E + YL +L + ++ I D+ AG+DT + TL L L ++Q K + EI++ +E K SY D+ +PY + I EV R +P +V H K+ GY + + ++ + ++ W +F F+ + E K E F PF G R C+GE LAR E+ L +V L+ ++ N++
Sbjct: 36 LFGNLLELNINNPLKDFERLANRYGNIYSLYFGSKPWVVLNGFEALKEALVTKAVDFAGRPQDLMVNRVTKGGGVILSDYGPSWKEHRRFALMTLRNFGLGKQSMEERILGEVSHIIDKLEKRVGTAFDPQTMFHNAASNIICIVLFGSRYDYDDEFLKLFIH----LYTENAKIANGPWAMIYDTFPMFRYLP---LPFRKAFANASKARELSTQLVKEHKKTWVPGE--PRDFIDCYLDELDKRG---NDGSSFSEAQLILYVLDLHFAGTDTTSNTLLTGFLYLMTHPEVQAKCQQEIDDVLEDKDQA--SYEDRHSMPYTQAVIHEVQRVANTVPLSVFHCTTKDTELMGYNIPKGTFVIPNLGSALKEEGQWKFPHEFNPANFLNEQGEFEK--PEAFVPFSAGPRVCLGEGLARMELFLVMVTLLRRFQFVWPNDA 461
BLAST of Cytochrome P450 2W1 vs. Ensembl Zebrafish
Match: cyp1a (cytochrome P450, family 1, subfamily A [Source:ZFIN;Acc:ZDB-GENE-011219-1]) HSP 1 Score: 117.472 bits (293), Expect = 1.740e-27 Identity = 116/447 (25.95%), Postives = 205/447 (45.86%), Query Frame = 2
Query: 368 LFKNLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELY--KYVSKRRGVLSSDGQI--WVLYRKLTTKALHEIS---HKTRGFEDVITENIK-------LLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNV----QIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELES-SSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQ-ENFYPFGTGKRNCIGESLARKEVLLTLVALICHYK 1645
+ N+ I +N + M K YG ++ +I + VVL ++ +A G SGRP ELY K++S + + S Q+ W RKL AL S K+ + + E+I L+ + + GS +I I F DD+++ + + +I+ S N P +P L+ +PS +KK +D N + + E+ +T + ++ I + + + K+ E + ++D + +D+ GAG DT++ L+W + L ++Q +L+ E++E + S D++ LP L SFI E+ R+ + +P T+ H K+ +GY + ++ + + + NH+ ++W + FI DRF+ ++ L+ E FG GKR CIGES+ R EV L L L+ K
Sbjct: 53 IIGNVLEIGNNPHLSLTAMSKCYGPVFQIQIGMRPVVVLSGNDVIRQALLKQGEEFSGRP--ELYSTKFISDGKSLAFSTDQVGVWRARRKLALNALRTFSTVQGKSPKYSCALEEHISNEGLYLVQRLHSVMKADGSFDPFRHIVVSVANVICGICFGRRHSHDDDELVRLVNMSDEFGKIVGSGN--------PADFIPFLRI-LPST-TMKKFLDINERFSKFMKRLVMEHYDTFDKDNIRDITDSLINHCEDRKLDENSNLQVSDEKIVGIVNDLFGAGFDTISTALSWAVVYLVHYPEVQERLQRELDEKIGKDRTPLLS--DRANLPLLESFILEIFRHSSFLPFTIPHCTSKDTSLNGYFIPKDTCVFVNQWQVNHDPELWKDPSSFIPDRFLTADGTELNKLEGEKVLVFGLGKRRCIGESIGRAEVFLFLAILLQRLK 485
BLAST of Cytochrome P450 2W1 vs. Ensembl Xenopus
Match: slc25a36 (Xenopus tropicalis uncharacterized LOC100124950 (LOC100124950), mRNA. [Source:RefSeq mRNA;Acc:NM_001102889]) HSP 1 Score: 117.857 bits (294), Expect = 1.448e-27 Identity = 110/423 (26.00%), Postives = 193/423 (45.63%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNL-FHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVL--------RIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE 1651
FME+ K YG ++S ++ ++ VVL + +A + SGRP T L + SK G++ ++G+ W + R+ T L + + ED I+E L+ + G + L ++ II I+ N D+ D K IK+V N N P+ +L PS++ RI + N N L E++ + K+ + N+ + + F +KQ Q K + H D N ++ GAG +T + TL W LL+ +IQ K++ EI+ + + Q+PY + I E+ R+ ++P V H ++ F GY L + + + + + D+F + F++++ +K+ E F PF GKR C GE+LA+ E+ L L+ ++ +
Sbjct: 55 FMELAKKYGPVFSVQLGTKKTVVLCGTDAVKDALINYADEFSGRPKTPLSEQASKGNGIIFANGENWKVMRRFTLSTLRDFGMGKKTIEDRISEESDCLVETFKSHKGKPFDNTLILNAAVANIIVHILLNHRFDYQDPTFLKLIKSV------NDNVRNGARPII---VLYNAFPSIIRWIPGTHKRIFASSQNFFNFLKEIFMKRKDQLDVND-QRDLVDAFLVKQ-QEEKSSSTKFFH--DENLKVLIGNLFGAGMETTSTTLRWGILLMMKYPEIQKKVQDEIDRVMGSTEP---RPEHRKQMPYTDAVIHEIQRFADLVPNGVPHATTTDVTFRGYFLPKGTQVFPLLTSVLRDKAYFKKPDEFYPEHFLDSEGNFLKN--EAFLPFSAGKRICAGETLAKMELFLFFTKLLQNFTFQ 459
BLAST of Cytochrome P450 2W1 vs. Ensembl Xenopus
Match: cyp1a1 (cytochrome P450 family 1 subfamily A member 1 [Source:NCBI gene;Acc:100037911]) HSP 1 Score: 116.701 bits (291), Expect = 5.369e-27 Identity = 118/480 (24.58%), Postives = 222/480 (46.25%), Query Frame = 2
Query: 377 NLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGV-LSSD-GQIWVLYRKLTTKALHEISHKTRGF--------EDVITENIKLLLNY---IDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCET-NELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKI-KHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFA-PFCH---NLKFSRISN 1756
NL + N + +M + YG+++ +I + +VL E +A +GRP ++ V + + SSD G++W R+L AL + E++ITE L+ + ID + G +I + F + DDE++ NV +T + + P +P+L+Y S ++ K + N L + K +KE+ +T ++ I + ++ Q +V E + L++ + +D+ GAG DT+ L+W + L IQ +++ E+++ + + SD++QLPY +FI E+ R+ + +P T+ H K+ + +GY + + +L + + NH+ ++W + KF +RF+ N + K E FG GKR C+GE++ R EV L L ++ + + KL+ ++ + GL CH L+F+ ++N
Sbjct: 59 NLLSLSKNPHLSLTKMSETYGDVFQIQIGTKPMLVLSGLETLRQALIRQSDEFAGRPDLFTFRLVGDGQSMTFSSDSGEVWRARRRLAQNALKTFATSPSPTSSNSCLVEENIITEAEYLIRKFKELID-DKGEFDPYRYVVVSVANVICGMCFGKRYNHDDEELL----NVVNLTDEFGAAAASGNPADFIPILQYLPNSSMKAFKEI--NQKFLAFMQKFTKEHYKTFDKNHIRDITDSLIQHSQEKRVDENSNIQLSNEKIVNIVNDLFGAGFDTITTALSWSLMYLVAHPNIQQRIQDELDQVIGRERRP--RLSDRAQLPYTEAFILEMFRHSSFMPFTIPHCTTKDTMLNGYFIPKGICVLINQWQVNHDPNLWQDPFKFCPERFLNNDGTMVNKTEMEKVMIFGLGKRRCVGEAIGRMEVFLFLTTMLQQMQFFKQDGEKLD----MSPQYGLTMKHKRCHLTAKLRFALLTN 525
BLAST of Cytochrome P450 2W1 vs. Ensembl Xenopus
Match: cyp2f1 (cytochrome P450 2K1 [Source:NCBI gene;Acc:100490476]) HSP 1 Score: 115.161 bits (287), Expect = 1.274e-26 Identity = 109/451 (24.17%), Postives = 201/451 (44.57%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLL-NYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNV--------NILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNL 1735
FME K YG ++S ++ + +VL + +A + G SGRP ++ +SK GV+ +DG+ W + R+ L + + ED I E L+ + + + ++ II I+ N ++ D + K IK+V S N+ + + P+ +L PS++ V N L E + + ++ + N+ + I F +KQ Q K ++ H D N D+ AG +T + TL W L++ IQ K++ EI+ + + Q+PY + I E+ R+ ++P + H +++ F GY L + ++ + + D + ++F + F+++K +K+ E F PF GKR+C+GE+LA+ E+ L L+ ++ T + E L + L P H +
Sbjct: 55 FMEFSKKYGPVFSIQLGLNKAIVLCGADAVKDALINHGDEFSGRPKIPVFDQISKGYGVVFADGENWKVMRRFALSTLRDFGMGRKTIEDTIVEESGCLVETFKSHEAKPFDNTLILNAAVANIIVHILLNHRFEYQDPTLIKLIKSV----SENVKIAGS--PIV---MLYNTYPSIMGWIPGSHKTVFENFQKLSNFLKETFTKRRDQLDVND-QRDLIDAFLVKQ-QEEKSSSKKFFH--DENLKVLLGDLFAAGMETTSTTLRWGILMMMKYPDIQKKVQDEIDRVIGSAEP---RLEHRKQIPYTDAVIHEIQRFANLVPIVLPHSITEDVTFRGYFLPKGTQVIPLLISVMQDKDYFQKPEEFYPEHFLDSKGNFVKN--EAFLPFSVGKRSCVGETLAKMELFLFFTKLLQNF----TFQPPPGVEVQLTCGDALTSIPLDHQI 483
BLAST of Cytochrome P450 2W1 vs. Ensembl Xenopus
Match: cyp2f1 (cytochrome P450 2K1 [Source:NCBI gene;Acc:100490476]) HSP 1 Score: 114.005 bits (284), Expect = 2.432e-26 Identity = 101/422 (23.93%), Postives = 190/422 (45.02%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLR----IKKAMDNNV----NILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE 1651
FME+ K YG+++S ++ ++ VV+ + +A + S RP ++ SK GV ++G+ W + R+ T L + + ED I E L+ G + + ++ II I+ N D+ D + K I I S N+ S A P+ LL PS++ K++ N+ N L E + + ++ + N+ + I F +KQ + + ND N +D+ GAG +T + TL W L + IQ K++ EI++ + + ++PY + I E+ R + P H ++ F GY + + ++ + + D + ++F + F++++ +K+ E F PF G+R C+GE+LA+ E+ L L+ ++ +
Sbjct: 55 FMELAKKYGSVFSIQLGPEKLVVVCGADAVKDALVNHADEFSARPTIPVFDKTSKGHGVFFANGENWKVMRRFTLSTLRDFGMGKKTIEDRICEESDFLMETFKSYKGKPFDNTMIMNAAVANIIVHILLNHRFDYQDPTLLKLIN----IVSENI--SIAAKPIV---LLYNAYPSIMEWVPGTHKSVAENMLKLYNFLRETFTQHRDQLDVND-QRDLIDVFLVKQQEEKP---SSTKFFNDQNLTVLLADLFGAGMETTSTTLRWGLLFIMKYPDIQKKVQDEIDKVIGSAQP---RLEHRKKMPYTDAVIHEIQRLGNLAPNVGHETTTDVTFRGYFIPKGTQVIILLTSVLQDKDYFKKPEEFYPEHFLDSEGNFVKN--EAFLPFSAGRRICVGETLAKMELFLFFTKLLQNFTFQ 458
BLAST of Cytochrome P450 2W1 vs. Ensembl Xenopus
Match: gins4 (GINS complex subunit 4 (Sld5 homolog) [Source:Xenbase;Acc:XB-GENE-949838]) HSP 1 Score: 113.235 bits (282), Expect = 4.958e-26 Identity = 109/430 (25.35%), Postives = 198/430 (46.05%), Query Frame = 2
Query: 407 KFFMEMHKIYGNIWSFRIINQRYVVL-GAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYID-RNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIK-NVQIITSSNLTFSNA--VFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESS-----SIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTI----IPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIEL 1654
K +M K YG+I++ + + VVL G ++ HS LSGRP+ ++ RG+ +++G W R+ L + RG E I E + L+ + +N I S+L +I +VF +D ++ +K N +++ + FP L++Y + A+D + K+ + +E+ SS + ++YL Q++ TK E ++ N I+ D+ AG++T A +L W L + +IQ K++ E++ ++ + + Y D+ +LP+ + I EV RY I IPR+ ++ + +GY+L +N I+L + + H+ W KF + F++ + + E F PF G R C+GE LAR E+ + ++ + IEL
Sbjct: 68 KTLRKMAKSYGDIYTLWLGHTPLVVLSGCKSVRNGLITHS-EELSGRPVDGFMTALTNERGIGTTNGHTWKQQRRFGLMTLRNLGLGKRGLESRIQEEAQCLVESLAAKNGEPINPSDLIVLAVANVISAVVFGHRFSIEDPTFQEMVKCNSSLVSGLGTAWGRMYDAFPW----LMRYVPGPHQKSFAAIDYLAAFI-------KKEIKLHEINSSKDDPQDMIDYYLTQIEKTK--HELDTTFDEENMIQVVIDLFIAGTETTAISLQWALLYMVAFPEIQKKVQKELDTVLDGSPLAY--YEDRKKLPFTNAVIHEVQRYGNIASVGIPRSC---IRKVTVNGYQLNKNTIVLPNLDSVLHDQRQWETPYKFNPNHFLDKNGDFCTN--EAFLPFSAGHRVCLGEQLARFELFIFFTTILRRFSIEL 476
BLAST of Cytochrome P450 2W1 vs. Ensembl Mouse
Match: Cyp2c29 (cytochrome P450, family 2, subfamily c, polypeptide 29 [Source:MGI Symbol;Acc:MGI:103238]) HSP 1 Score: 122.479 bits (306), Expect = 3.438e-29 Identity = 113/440 (25.68%), Postives = 203/440 (46.14%), Query Frame = 2
Query: 398 NENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEK----IKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE-LTNESKLNFEEILNG 1696
N ++ F K YG +++ + ++ V+L E EA G +GR + + + K GV+ S+G W R+ T L + R ED + E + L+ + + GS + + +I I+F D+ D++ + K +NV+I++S L N+ FP L+ YC S +I K + + L E KE KE+ + I + +KQ Q+ + E + N +D+ GAG++T + TL + LLL + K++ EI+ V D+S +PY + I EV R+ ++P ++ H ++ F Y + + ++ + H++ +PN + F F+ K + F PF TGKR C GE LAR E+ L L ++ ++K++ L + +++ ++NG
Sbjct: 49 NISQSFTNFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNS-FP----SLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTN-PRDFIDYYLIKQKQVNHI---EQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSP--CMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGNFKK--SDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLKSLVHPKEIDITPVMNG 475
BLAST of Cytochrome P450 2W1 vs. Ensembl Mouse
Match: Cyp2c29 (cytochrome P450, family 2, subfamily c, polypeptide 29 [Source:MGI Symbol;Acc:MGI:103238]) HSP 1 Score: 121.324 bits (303), Expect = 5.473e-29 Identity = 111/430 (25.81%), Postives = 199/430 (46.28%), Query Frame = 2
Query: 428 KIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEK----IKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE-LTNESKLNFEEILNG 1696
K YG +++ + ++ V+L E EA G +GR + + + K GV+ S+G W R+ T L + R ED + E + L+ + + GS + + +I I+F D+ D++ + K +NV+I++S L N+ FP L+ YC S +I K + + L E KE KE+ + I + +KQ Q+ + E + N +D+ GAG++T + TL + LLL + K++ EI+ V D+S +PY + I EV R+ ++P ++ H ++ F Y + + ++ + H++ +PN + F F+ K + F PF TGKR C GE LAR E+ L L ++ ++K++ L + +++ ++NG
Sbjct: 20 KAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNS-FP----SLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTN-PRDFIDYYLIKQKQVNHI---EQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSP--CMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGNFKK--SDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLKSLVHPKEIDITPVMNG 436
BLAST of Cytochrome P450 2W1 vs. Ensembl Mouse
Match: Cyp2b13 (cytochrome P450, family 2, subfamily b, polypeptide 13 [Source:MGI Symbol;Acc:MGI:88599]) HSP 1 Score: 120.168 bits (300), Expect = 1.931e-28 Identity = 108/424 (25.47%), Postives = 196/424 (46.23%), Query Frame = 2
Query: 407 KFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLR-IKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESK 1669
K F+ + + +G++++ + + VVL + EA ++ SGR + V + G+ S G+ W R+ + + E R E+ I E + L+ + + G+ + + F +T II IVF D+ DE+ + + + I S +FS +F L + LLKY P V R I K +N +T + K + E + YL L++ K + + N + + + AG++T + TL LL+ + K++ EI++ + + + D++++PY + I E+ R+ I+P HR K+ +F GY L +N + ++ H+ + D F D F++ K E F PF TGKR C+GES+AR E+ L +++ ++ + SK
Sbjct: 53 KCFIHLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVNNAEAFSGRGTIAAAQLVMQDYGIFFSSGERWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGAPLDPTFFFQCVTANIICSIVFGERFDYTDEQFLRLLNLMYQIYSLLRSFSCQMFELFSG-LLKY-FPGVHRQIAKNQQEILNFITH--RVEKHRATLDPSEPRDFIDTYL--LRMEKEKSNHNTEFHHQNLMMSVLSLFFAGTETTSTTLCCGFLLMLMYPHVAEKVQKEIDQVIGSHRLP--TLDDRTKMPYTDAVIHEIQRFSDIVPTGAPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLDANGALKK--SEAFLPFSTGKRICLGESIARNELFLFFTSILQNFSVASPVASK 466
BLAST of Cytochrome P450 2W1 vs. Ensembl Mouse
Match: Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1 [Source:MGI Symbol;Acc:MGI:1918769]) HSP 1 Score: 119.013 bits (297), Expect = 6.970e-28 Identity = 112/466 (24.03%), Postives = 206/466 (44.21%), Query Frame = 2
Query: 398 NENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRG-VLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNP-GSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNI-LTELWKESKENCETNELESSSIGEF---YLKQLQLTKVYEEEHQHLNDMNFIRNF-----SDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
++ + M ++YGNI+SF I ++ VVL EA S RP L ++K +G V + G IW R+ + L E I E + + ++ + + II + F D+ +++ KK + + ++I S L N P Y + + ++ +++ L + +E +E+ L++S+ +F YL + EEE +F ++ D+ AG+DT +L WC L ++ +Q K+ EI + S +DK+Q+PY + I EV R ++P + H + + G+ + + ++L + ++ + + IW D F RF++++ + +K +E F PFG GKR C+GE LA+ E+ L V+L+ + L S+ + ++ G GL AP N+ S+
Sbjct: 88 GQHVYLARMARVYGNIFSFFIGHRLVVVLSDFHSVREALVQQAEVFSDRPRMPLISIMTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKEAMQKHGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINIC------PWFYYLPFGPFKELRQIERDISCFLKNIIREHQES-----LDASNPQDFIDMYLLHM------EEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQKKVHEEIERVIGCDRAP--SLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLK--RETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQTFTFALPEGSE---KPVMTGRFGLTLAPHPFNVTISK 529
BLAST of Cytochrome P450 2W1 vs. Ensembl Mouse
Match: Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1 [Source:MGI Symbol;Acc:MGI:1918769]) HSP 1 Score: 119.013 bits (297), Expect = 6.970e-28 Identity = 112/466 (24.03%), Postives = 206/466 (44.21%), Query Frame = 2
Query: 398 NENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRG-VLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNP-GSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNI-LTELWKESKENCETNELESSSIGEF---YLKQLQLTKVYEEEHQHLNDMNFIRNF-----SDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
++ + M ++YGNI+SF I ++ VVL EA S RP L ++K +G V + G IW R+ + L E I E + + ++ + + II + F D+ +++ KK + + ++I S L N P Y + + ++ +++ L + +E +E+ L++S+ +F YL + EEE +F ++ D+ AG+DT +L WC L ++ +Q K+ EI + S +DK+Q+PY + I EV R ++P + H + + G+ + + ++L + ++ + + IW D F RF++++ + +K +E F PFG GKR C+GE LA+ E+ L V+L+ + L S+ + ++ G GL AP N+ S+
Sbjct: 88 GQHVYLARMARVYGNIFSFFIGHRLVVVLSDFHSVREALVQQAEVFSDRPRMPLISIMTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKEAMQKHGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINIC------PWFYYLPFGPFKELRQIERDISCFLKNIIREHQES-----LDASNPQDFIDMYLLHM------EEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQKKVHEEIERVIGCDRAP--SLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLK--RETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQTFTFALPEGSE---KPVMTGRFGLTLAPHPFNVTISK 529
BLAST of Cytochrome P450 2W1 vs. UniProt/SwissProt
Match: sp|P00182|CP2C3_RABIT (Cytochrome P450 2C3 OS=Oryctolagus cuniculus OX=9986 GN=CYP2C3 PE=1 SV=2) HSP 1 Score: 129.028 bits (323), Expect = 1.110e-30 Identity = 117/469 (24.95%), Postives = 218/469 (46.48%), Query Frame = 2
Query: 377 NLFRIKSNE-NKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDR-NPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIK----NVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDM---NFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE-LTNESKLNFEEILNGENGLVFAPFCHNLKFSRI 1750
NL ++++ + NK + K YG+I++ + VVL E EA G SGR + ++ V+K G++ S G+ W R+ + L + + E+ I E L+ + + N + L + +I ++F D+DDEK K IK N +++ + + N P+L Y S ++ K +D + + E +E +E+ ++N + F L K+ +E+H+ ++ N I D+ AG+DT + TL + LLL +I K++ EI + D++++PY + + E+ RY ++P ++ H +++ F+GY + + I+ + ++ +PN +KF F++ K + F PF GKR C+GE LAR E+ L L ++ H+ ++ L + ++ + ENG V P + L F +
Sbjct: 41 NLLQLETKDINKSLSMLAKEYGSIFTLYFGMKPAVVLYGYEGVIEALIDRGEEFSGRGIFPVFDRVTKGLGIVFSSGEKWKETRRFSLTVLRNLGMGKKTIEERIQEEALCLIQALRKTNASPCDPTFLLFCVPCNVICSVIFQNRFDYDDEKFKTLIKYFHENFELLGTPWIQLYNIF------PILHYLPGSHRQLFKNIDGQIKFILEKVQEHQESLDSNN-PRDFVDHF------LIKMEKEKHKKQSEFTMDNLITTIWDVFSAGTDTTSNTLKFALLLLLKHPEITAKVQEEIEHVIGRHRSP--CMQDRTRMPYTDAVMHEIQRYVDLVPTSLPHAVTQDIEFNGYLIPKGTDIIPSLTSVLYDDKEFPNPEKFDPGHFLDESGNFKK--SDYFMPFSAGKRACVGEGLARMELFLLLTTILQHFTLKPLVDPKDIDPTPV---ENGFVSVPPSYELCFVPV 489
BLAST of Cytochrome P450 2W1 vs. UniProt/SwissProt
Match: sp|Q7Z449|CP2U1_HUMAN (Cytochrome P450 2U1 OS=Homo sapiens OX=9606 GN=CYP2U1 PE=1 SV=1) HSP 1 Score: 125.946 bits (315), Expect = 2.511e-29 Identity = 118/460 (25.65%), Postives = 212/460 (46.09%), Query Frame = 2
Query: 422 MHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRN------PGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNV-NILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNF-----SDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
+ ++YG+I+SF I + VVL EA S RP L V+K +GV+ + G +W RK + L E I E K + + ++ P SI ++ + + II + F D+ + + KK + + ++I +S + N P L Y + + ++ ++ + L ++ K+ +E+ + + YL + EEE ++ ++ +F + D+ AG+DT +L WC L ++ +Q K+ EI + S +DK+Q+PY + I EV R ++P + H +N + GY + + +IL + ++ + + IW + F +RF++++ + IK +E F PFG GKR C+GE LA+ E+ L V+L+ + L +SK + +L G GL AP N+ SR
Sbjct: 110 LARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSN-----IICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNIC------PWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDREN--PQDFIDMYLLHM------EEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAP--SLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIK--KETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSK---KPLLTGRFGLTLAPHPFNITISR 543
BLAST of Cytochrome P450 2W1 vs. UniProt/SwissProt
Match: sp|Q0IIF9|CP2U1_BOVIN (Cytochrome P450 2U1 OS=Bos taurus OX=9913 GN=CYP2U1 PE=2 SV=1) HSP 1 Score: 122.865 bits (307), Expect = 2.217e-28 Identity = 113/455 (24.84%), Postives = 207/455 (45.49%), Query Frame = 2
Query: 419 EMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRG-VLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNP-GSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNF-----SDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
++ ++YGNI+SF I + VVL EA S RP L ++K +G V + G +W RK + L E I E + + + ++ + ++ II + F D+ + + K+ + + +++ ++ L N L +P + +++ + L ++ K+ +E+ + + YL + EEE ++ ++ F ++ D+ AG+DT +L WC L ++ IQ K+ EI + S +DK+Q+PY + I EV R T++P ++ H + + G+ + + IIL + ++ + + IW + F DRF++++ + IK +E F PFG GKR C+GE LA+ E+ L V+L+ + L +SK IL G+ GL AP N+ S+
Sbjct: 109 DLGRVYGNIFSFLIGHYLVVVLNDFHSVREALVQQAEVFSDRPRVPLTSIMTKGKGIVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFRYVKEEMQKHGDAPFNPFPIVNNAVSNIICSLCFGRRFDYTNSEFKQMLNFMSRALEVCLNTQLLLVNICSWLYYLPFGPFK-----ELRQIEKDLTLFLKKIIKDHRESLDVEN--PQDFIDMYLLHV------EEEKKNNSNSGFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLHPNIQEKIHEEIARVIGADRAP--SLTDKAQMPYTEATIMEVQRLSTVVPLSIPHMTSEKTVLQGFTIPKGTIILPNLWSVHRDPAIWEKPNDFYPDRFLDDQGQLIK--KETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFVLPKDSK----PILTGKYGLTLAPHPFNIIISK 542
BLAST of Cytochrome P450 2W1 vs. UniProt/SwissProt
Match: sp|Q64458|CP2CT_MOUSE (Cytochrome P450 2C29 OS=Mus musculus OX=10090 GN=Cyp2c29 PE=1 SV=2) HSP 1 Score: 122.479 bits (306), Expect = 2.405e-28 Identity = 113/440 (25.68%), Postives = 203/440 (46.14%), Query Frame = 2
Query: 398 NENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEK----IKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE-LTNESKLNFEEILNG 1696
N ++ F K YG +++ + ++ V+L E EA G +GR + + + K GV+ S+G W R+ T L + R ED + E + L+ + + GS + + +I I+F D+ D++ + K +NV+I++S L N+ FP L+ YC S +I K + + L E KE KE+ + I + +KQ Q+ + E + N +D+ GAG++T + TL + LLL + K++ EI+ V D+S +PY + I EV R+ ++P ++ H ++ F Y + + ++ + H++ +PN + F F+ K + F PF TGKR C GE LAR E+ L L ++ ++K++ L + +++ ++NG
Sbjct: 49 NISQSFTNFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNS-FP----SLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTN-PRDFIDYYLIKQKQVNHI---EQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSP--CMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGNFKK--SDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLKSLVHPKEIDITPVMNG 475
BLAST of Cytochrome P450 2W1 vs. UniProt/SwissProt
Match: sp|Q4V8D1|CP2U1_RAT (Cytochrome P450 2U1 OS=Rattus norvegicus OX=10116 GN=Cyp2u1 PE=1 SV=1) HSP 1 Score: 122.479 bits (306), Expect = 3.447e-28 Identity = 113/459 (24.62%), Postives = 199/459 (43.36%), Query Frame = 2
Query: 410 FFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRG-VLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNP-GSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNI-LTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNF-----SDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
+ + ++YGNI+SF I ++ VVL + EA S RP L ++K +G V + G IW R+ + L E I E + + ++ + + II + F D+ +++ KK + + ++I S L N P Y + + ++ ++ L + KE +E+ + N + YL Q EE NF ++ D+ AG+DT +L WC L ++ +Q K+ EI + S +DK+Q+PY + I EV R ++P + H + + GY + + ++L + ++ + + IW D F RF++++ + +K +E F PFG GKR C+GE LA+ E+ L V+L+ + L S+ + I+ G GL AP N+ S+
Sbjct: 92 YLARLARVYGNIFSFFIGHRLVVVLSDFQSVREALVQQAEVFSDRPRMPLISILTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKAEMQKHGEAPFSPFPVISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINLC------PWFYYLPFGPFKELRQIERDITCFLKNIIKEHQESLDANN--PQDFIDMYLLHTQ------EEKDKCKGTNFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPGVQKKVHEEIERVIGRDRAP--SLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGYSIPKGTVVLPNLWSIHRDPVIWEKPDDFCPHRFLDDQGQLLK--RETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFALPEGSE---KPIMTGRFGLTLAPHPFNVTVSK 529
BLAST of Cytochrome P450 2W1 vs. TrEMBL
Match: A0A1I8HTI6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013417g2 PE=3 SV=1) HSP 1 Score: 162.155 bits (409), Expect = 1.825e-39 Identity = 117/458 (25.55%), Postives = 225/458 (49.13%), Query Frame = 2
Query: 419 EMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHS--GMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYID-RNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSN-AVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETN------ELESSS-----IGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFS 1744
+ K YG++ S+R+ +R+VVL + EA G SGR + ++ +G++SS+G++W +R+ K L + G ED I + ++ L + + + T+ + +I ++F D++ + ++ Q NL + A F PLL Y +P V+R+ + + +V ++ K + C+ +L S + F ++Q +L ++ +D R +++ AG+DT + T+ W L + Q ++++EI+ ++ + D+ ++PY +FI+EV R+ T+ P V HR +++ F GY + +D+I+ + Y +H+ ++W + + F +RF+ + + E+ PFG GKR C+GESLAR+E+ L + ++ + L +S N E+I G +G+V AP H + FS
Sbjct: 70 DWRKRYGDLVSYRLGARRFVVLNSYAAVKEALASQEFGDVFSGRMNSNYINSLTHGKGIVSSEGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISVMLFGYRAGSQDDRFEAFLAATQ----ENLQGGDLARFIPVGFPLL-YQIPGVMRLLELLGVDVYVVQRNLKVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNG--RKKDHTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEID--AQIGRNRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCTRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTGEYQP-NEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARLHPDSVKNLEDIKIGSDGIVHAPGAHRIIFS 517
BLAST of Cytochrome P450 2W1 vs. TrEMBL
Match: A0A1I8I1X1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013417g1 PE=3 SV=1) HSP 1 Score: 162.155 bits (409), Expect = 2.054e-39 Identity = 117/458 (25.55%), Postives = 226/458 (49.34%), Query Frame = 2
Query: 419 EMHKIYGNIWSFRIINQRYVVLGAPELQTEAF--KHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYID-RNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSN-AVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETN------ELESSS-----IGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFS 1744
+ K YG++ S+R+ +R+VVL + EA + G SGR + ++ +G++SS+G++W +R+ K L + G ED I + ++ L + + + T+ + +I ++F D++ + ++ Q NL + A F PLL Y +P V+R+ + + +V ++ K + C+ +L S + F ++Q +L ++ +D R +++ AG+DT + T+ W L + Q ++++EI+ ++ + D+ ++PY +FI+EV R+ T+ P V HR +++ F GY + +D+I+ + Y +H+ ++W + + F +RF+ + + E+ PFG GKR C+GESLAR+E+ L + ++ + L +S N E+I G +G+V AP H + FS
Sbjct: 70 DWRKRYGDLVSYRLGARRFVVLNSYAAVKEALVSQEFGDVFSGRMNSNYINSLTHGKGIVSSEGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISMMLFGYRAGSQDDRFEAFLAATQ----ENLQGGDLARFIPVGFPLL-YQIPGVMRLLELLGVDVYVVQRNLKVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNG--RKKDHTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEID--AQIGRDRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCPRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTGEYQP-NEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARLHPDSVKNLEDIKIGSDGIVHAPGAHRIIFS 517
BLAST of Cytochrome P450 2W1 vs. TrEMBL
Match: A0A267FGF7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002295g1 PE=3 SV=1) HSP 1 Score: 156.762 bits (395), Expect = 1.022e-37 Identity = 124/477 (26.00%), Postives = 222/477 (46.54%), Query Frame = 2
Query: 371 FKNLFRIKSNENKFFMEMH----KIYGNIWSFRIINQRYVVLGAPELQTEAFKHS--GMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSN-AVFPLTNVPLLKYCVPSVLRIKKAMD-------NNVNILTELWKESKENCETNELESSSIGEF---YLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
F NLF + E F+ H + YG++ SF ++R+V+L + + EA SGR + ++ +G++S++G++W +R+ K L + G E+ I + L +D P + L +I ++FN DE ++ + + NL +N F T P L Y +P +R+ + + N+ + ++ + N E S +F +L + Q +H +D +R +++ AG+DT + T+ W L A + Q+++ +E+ + Y DK + + +FI+EV RY T+ P +V HR +++ F GY + ND+I+ + Y +H+ ++W ++F +RF+ + E E PF GKR C+GESLAR+E+ L L + Y++EL + + ++I G GLV AP H + F R
Sbjct: 51 FGNLFNL---ERPTFLVAHSKWRRQYGDLVSFTFGSRRFVILNSYAVIKEALTSPEWAEVFSGRINSPFILSMTHGKGIVSAEGELWREHRRFALKVLRDFGFARSGTEEAIHAELAELQQTLDAEP-----AELVPRAIANVISVLLFNYRAGTQDEGFTDFM----LASQENLQGNNIGRFIPTAFPGL-YSIPGFMRLLQLIGVDVFVFKRNIEVTHRFCRDQIDRHRRNLAEVSEPADFLDAFLLEQQRLNSKRSDHS-FDDFQLVRTLTELFIAGTDTTSNTIRWALLYAALHPECQDRIAAEVE--AATGNSRLPVYRDKKAMHFTMAFIDEVQRYSTLAPFSVGHRCTRDIRFKGYDISSNDLIMVNLYGVHHDPELWDQPEQFRPERFINSSGEY--ETSEFLVPFSIGKRACLGESLARQELFLFLSGIFQAYRVELHKDCYKDLKDIEVGSAGLVHAPGKHQIIFHR 509
BLAST of Cytochrome P450 2W1 vs. TrEMBL
Match: A0A1I8I239 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 157.147 bits (396), Expect = 1.298e-37 Identity = 124/477 (26.00%), Postives = 222/477 (46.54%), Query Frame = 2
Query: 371 FKNLFRIKSNENKFFMEMH----KIYGNIWSFRIINQRYVVLGAPELQTEAFKHS--GMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSN-AVFPLTNVPLLKYCVPSVLRIKKAMD-------NNVNILTELWKESKENCETNELESSSIGEF---YLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
F NLF + E F+ H + YG++ SF ++R+V+L + + EA SGR + ++ +G++S++G++W +R+ K L + G E+ I + L +D P + L +I ++FN DE ++ + + NL +N F T P L Y +P +R+ + + N+ + ++ + N E S +F +L + Q +H +D +R +++ AG+DT + T+ W L A + Q+++ +E+ + Y DK + + +FI+EV RY T+ P +V HR +++ F GY + ND+I+ + Y +H+ ++W ++F +RF+ + E E PF GKR C+GESLAR+E+ L L + Y++EL + + ++I G GLV AP H + F R
Sbjct: 82 FGNLFNL---ERPTFLVAHSKWRRQYGDLVSFTFGSRRFVILNSYAVIKEALTSPEWAEVFSGRINSPFILSMTHGKGIVSAEGELWREHRRFALKVLRDFGFARSGTEEAIHAELAELQQTLDAEP-----AELVPRAIANVISVLLFNYRAGTQDEGFTDFM----LASQENLQGNNIGRFIPTAFPGL-YSIPGFMRLLQLIGVDVFVFKRNIEVTHRFCRDQIDRHRRNLAEVSEPADFLDAFLLEQQRLNSKRSDHS-FDDFQLVRTLTELFIAGTDTTSNTIRWALLYAALHPECQDRIAAEVE--AATGNSRLPVYRDKKAMHFTMAFIDEVQRYSTLAPFSVGHRCTRDIRFKGYDISSNDLIMVNLYGVHHDPELWDQPEQFRPERFINSSGEY--ETSEFLVPFSIGKRACLGESLARQELFLFLSGIFQAYRVELHKDCYKDLKDIEVGSAGLVHAPGKHQIIFHR 540
BLAST of Cytochrome P450 2W1 vs. TrEMBL
Match: A0A267F088 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002295g2 PE=3 SV=1) HSP 1 Score: 155.992 bits (393), Expect = 2.071e-37 Identity = 124/477 (26.00%), Postives = 221/477 (46.33%), Query Frame = 2
Query: 371 FKNLFRIKSNENKFFMEMH----KIYGNIWSFRIINQRYVVLGAPELQTEAFKHS--GMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSN-AVFPLTNVPLLKYCVPSVLRIKKAMD-------NNVNILTELWKESKENCETNELESSSIGEF---YLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
F NLF + E F+ H + YG++ SF ++R+V+L + + EA SGR + ++ +G++S++G++W +R+ K L + G E+ I + L +D P L +I ++FN DE ++ + + NL +N F T P L Y +P +R+ + + N+ + ++ + N E S +F +L + Q +H +D +R +++ AG+DT + T+ W L A + Q+++ +E+ + Y DK + + +FI+EV RY T+ P +V HR +++ F GY + ND+I+ + Y +H+ ++W ++F +RF+ + E E PF GKR C+GESLAR+E+ L L + Y++EL + + ++I G GLV AP H + F R
Sbjct: 51 FGNLFNL---ERPTFLVAHSKWRRQYGDLVSFTFGSRRFVILNSYAVIKEALTSPEWAEVFSGRINSPFILSMTHGKGIVSAEGELWREHRRFALKVLRDFGFARSGTEEAIHAELAELQQTLDAEP-----DELVPRAIANVISVLLFNYRAGTQDEGFTDFM----LASQENLQGNNIGRFIPTAFPGL-YSIPGFMRLLQLIGVDVFVFKRNIEVTHRFCRDQIDRHRRNLAEVSEPADFLDAFLLEQQRLNSKRSDHS-FDDFQLVRTLTELFIAGTDTTSNTIRWALLYAALHPECQDRIAAEVE--AATGNSRLPVYRDKKAMHFTMAFIDEVQRYSTLAPFSVGHRCTRDIRFKGYDISSNDLIMVNLYGVHHDPELWDQPEQFRPERFINSSGEY--ETSEFLVPFSIGKRACLGESLARQELFLFLSGIFQAYRVELHKDCYKDLKDIEVGSAGLVHAPGKHQIIFHR 509
BLAST of Cytochrome P450 2W1 vs. Ensembl Cavefish
Match: ENSAMXT00000048689.1 (cytochrome P450 2J6-like [Source:NCBI gene;Acc:103028795]) HSP 1 Score: 124.405 bits (311), Expect = 6.218e-30 Identity = 116/439 (26.42%), Postives = 201/439 (45.79%), Query Frame = 2
Query: 434 YGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGV-LSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS--IRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQL-QLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIEL-TNESKLNFEEILNGENGLVFAPFCHN 1732
YG + + + +VL E+ EAF H+G SGRP + +++ G+ + S G W R+ L + + E+ +TE + L+ + ++ G + +S++ II IVF D++D++ +K V +F VF L VP +K+ +I K ++ + ++ +E + N L+ ++ +F L ++TK E ++ N I + +D+ AG+DT A TL W + + D +Q + EI + S D++QLPY + + E+ R I+P V H + HGY + ++ + + + W + D F + F++ KE+ K+ E F PF G R C+GESLAR E+ + +LI K E + N +NG GLV PF +N
Sbjct: 69 YGEMSCLFLGGRPIIVLNKMEIVKEAFVHNGAVFSGRPHMPVLDWITDGLGIIMVSYGNAWKQQRRFALHTLRDFGLGKKSVEERVTEEARYLVEEMLKHEGKAFFPIHPIMNSVS-NIICSIVFGDRYDYEDKRFAHLLKLVTENVRLTGSFVGQVFNL--VPFIKHFPGPHQKIWKNANSLKCFIRDIVEEHR-----NTLDPENLRDFIDAYLVEMTKQEAIEESTFHEENMIMSTADLFLAGTDTTATTLRWGIIYMMDHPDVQERCHEEIVRVLGFDRSP--SMDDRAQLPYTHATLHEIMRRSNIVPLGVGHETTQPTQLHGYHIPAGTQVVANFTAIMSDRNHWKHPDVFNPENFLDEKEQFCKN--EFFLPFSMGPRVCLGESLARTELFIFFSSLIQRLKFSWPPGEPRPN----MNGALGLVRCPFPYN 491
BLAST of Cytochrome P450 2W1 vs. Ensembl Cavefish
Match: cyp2u1 (cytochrome P450 2U1 [Source:NCBI gene;Acc:103032979]) HSP 1 Score: 124.405 bits (311), Expect = 8.261e-30 Identity = 109/450 (24.22%), Postives = 194/450 (43.11%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRG-VLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENI-----KLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFS-NAVFPLTNV-PLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNL 1735
M++ ++YGN++S + NQ VVL E+ +A + S RP L ++KR+G V + G +W RK AL E I E +LL + + + L + +I I DE+ + + + +S L S N+ L N+ P L Y V + + ++ ++ + E I + ++ L K E E ++ D+ AG+DT ++ W L ++ +Q K++ EI+ V S S +DK LPY + I EV R ++P ++ H K F GY + + +I+ + ++ + + +W N D F RF++ + + ++ E F PFG G+R C+GE LA+ E+ L +++ + L + +NG GL AP+ + +
Sbjct: 93 LMQLSRLYGNVYSIFVGNQLLVVLNGYEMVKDAMTNYAEVFSDRPDIPLVSILTKRKGIVFAPYGTVWRRQRKFCHTALRNFGLGKLSLEPCIHEGFTIVKAELLKRSQEAGAAGMDLTPLISNAVSNVISSISLGQRFHHQDEEFRTQLN----LMASGLEISVNSPALLINIFPWLYYLPFGVFKQLRKVERDITAFLKKIIAKHRATLDPENPRDFIDIYLIEMLAQEKAAELEEGGFSEEYLFFIIGDLFIAGTDTTTNSILWLVLYMSLYPDVQEKVQKEIDAV--VGSGRLPSLTDKGTLPYTEATIMEVQRMTVVVPLSIPHMASKTTEFRGYTIPKGTVIIPNLWSVHRDPTVWENPDDFCPSRFLDEQGQLLR--SEYFIPFGIGRRVCMGEQLAKMELFLMFTSMMQAFTFSLPEGHQ---PPPMNGRFGLTLAPYPYKV 531
BLAST of Cytochrome P450 2W1 vs. Ensembl Cavefish
Match: ENSAMXT00000034412.1 (cytochrome P450 2B4-like [Source:NCBI gene;Acc:111195741]) HSP 1 Score: 122.479 bits (306), Expect = 2.465e-29 Identity = 114/439 (25.97%), Postives = 197/439 (44.87%), Query Frame = 2
Query: 362 VVLFKNLFRIK-SNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDN-------NVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYK 1645
V +F N+F++ SN K F + + YGN++S + V+L + EA SGRP L ++++ +G+ D G W R+ +L + ED I I+ L+ +D++ G + LFH II+ ++F I ++ DE +K+Y+ + T F ++ P L+ +P L +KA+ + N N++ SK E + + YL +L+ K E + + +R D+ AG+DT + TL L L IQ K + EI+E ++ K+ S+ D+ +PY + I E R +P +V H ++ GY + ++ ++ + + W +F D F+ + + K E F PF G R C+GE LAR E+ L LV L+ ++
Sbjct: 34 VPIFGNVFQLNISNPLKDFERIAERYGNVYSLYFGGRPAVILTGFKAVKEALVTKAADFSGRPQNVLVSHITEGKGIAFVDYGPYWKEQRRFALMSLRNFGLGKQSMEDRILGEIQHLVVCMDKSVGGFMNPDTLFHEAASNIIYLVLFGIRYEYGDETLKQYVTSFVESTKIANGFWGMIY--DTFPALR-GLP--LPFRKAITHFDIVKNINANMV------SKHKPSRVPGEPKNFVDCYLDELEKQK--ENDGSSFTEGQLVRTIMDLHAAGTDTTSNTLRTAFLYLITHPDIQEKCQREIDEALKGKAHA--SFEDRHDMPYTQAVIHESLRIAKTVPLSVPHCTTRDTELMGYSIPKDTLVFPNLASVLSEEGQWKFPHEFNPDNFLNDHGQFEK--PEAFLPFSAGPRVCLGEGLARMELFLILVTLLRRFQ 455
BLAST of Cytochrome P450 2W1 vs. Ensembl Cavefish
Match: ENSAMXT00000057567.1 (cytochrome P450 2B4-like [Source:NCBI gene;Acc:111195741]) HSP 1 Score: 122.094 bits (305), Expect = 3.031e-29 Identity = 114/435 (26.21%), Postives = 195/435 (44.83%), Query Frame = 2
Query: 362 VVLFKNLFRIK-SNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS-IRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDN-------NVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALI 1633
V +F N+F++ SN K F + + YGN++S + V+L + EA SGRP L ++++ +G+ D G W R+ +L + ED I I+ L+ +D++ G + LFH II+ ++F I ++ DE +K+Y+ + T F ++ P L+ +P L +KA+ + N N++ SK E + + YL +L+ K E + + +R D+ AG+DT + TL L L IQ K + EI+E ++ K+ S+ D+ +PY + I E R +P +V H ++ GY + ++ ++ + + W +F D F+ + + K E F PF G R C+GE LAR E+ L LV L+
Sbjct: 34 VPIFGNVFQLNISNPLKDFERIAERYGNVYSLYFGGRPAVILTGFKAVKEALVTKAADFSGRPQNVLVSHITEGKGIAFVDYGPYWKEQRRFALMSLRNFGLGKQSMEDRILGEIQHLVVCMDKSVGGFMNPDTLFHEAASNIIYLVLFGIRYEYGDETLKQYVTSFVESTKIANGFWGMIY--DTFPALR-GLP--LPFRKAITHFDIVKNINANMV------SKHKPSRVPGEPKNFVDCYLDELEKQK--ENDGSSFTEGQLVRTIMDLHAAGTDTTSNTLRTAFLYLITHPDIQEKCQREIDEALKGKAHA--SFEDRHDMPYTQAVIHESLRIAKTVPLSVPHCTTRDTELMGYSIPKDTLVFPNLASVLSEEGQWKFPHEFNPDNFLNDHGQFEK--PEAFLPFSAGPRVCLGEGLARMELFLILVTLL 451
BLAST of Cytochrome P450 2W1 vs. Ensembl Cavefish
Match: ENSAMXT00000034712.1 (cytochrome P450 2J6-like [Source:NCBI gene;Acc:103028795]) HSP 1 Score: 120.168 bits (300), Expect = 1.622e-28 Identity = 115/439 (26.20%), Postives = 198/439 (45.10%), Query Frame = 2
Query: 434 YGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGV-LSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGS--IRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQL-QLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIEL-TNESKLNFEEILNGENGLVFAPFCHN 1732
YG + + + +VL E+ EAF H+G SGRP + +++ G+ + S G W R+ L + + E+ +TE + L+ + ++ G + +S++ II IVF D++D++ +K V +F VF L VP +K+ +I K ++ + ++ +E + N L+ ++ +F L ++TK E ++ N I + +D+ AG+DT A TL W + + D +Q + EI + S D++QLPY + + E+ R I+P V H + HGY + ++ + + W D F + F++ K + K+ E F PF G R C+GESLAR E+ + +LI K E + N +NG GLV PF +N
Sbjct: 69 YGEMSCLFLGGRPIIVLNKMEIVKEAFVHNGAVFSGRPHMPVLDWITDGLGIIMVSYGNAWKQQRRFALHTLRDFGLGKKSVEERVTEEARYLVEEMLKHEGKAFFPIHPIMNSVS-NIICSIVFGDRYDYEDKRFAHLLKLVTENVRLTGSFVGQVFNL--VPFIKHFPGPHQKIWKNANSLKCFIRDIVEEHR-----NTLDPENLRDFIDAYLVEMTKQEAIEESTFHEENMIMSTADLFLAGTDTTATTLRWGIIYMMDHPDVQERCHEEIVRVLGFDRSP--SMDDRAQLPYTHATLHEIMRRSNIVPLGVGHETTQPTQLHGYHIPAGTQVVANFTAIMSERNHWKYPDVFNPENFLDEKGQFCKN--EFFLPFSMGPRVCLGESLARTELFIFFSSLIQRLKFSWPPGEPRPN----MNGALGLVRCPFPYN 491
BLAST of Cytochrome P450 2W1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011205.1 (pep scaffold:Pmarinus_7.0:GL477378:108537:110066:1 gene:ENSPMAG00000010178.1 transcript:ENSPMAT00000011205.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.9669 bits (219), Expect = 5.350e-19 Identity = 91/415 (21.93%), Postives = 181/415 (43.61%), Query Frame = 2
Query: 419 EMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIP-RTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYK 1645
E+ K YG + S + V + + E H G + RP T K V+ G++ + G+ W+ +R+ T L E I + L+ + + +S II +V ++ D++ + ++ N+Q+ + T N +FP L+ + P + I K+M + + ++ E + + ++ + + YL QL+ + + ++ + I D+ AG++T + TL W L + +IQ + EI++ V + D+ LPYL + I E+ R+ I+P H ++ F Y + + II+ + + + + W +F + F++ + +K + F PF G R C+GE+LA+ E+ L +L+ H++
Sbjct: 78 EVTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADRPNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQKGSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLGTLCN-IFPF----LMDFPGPQQI-IFKSMAKSKQFIRDIISE--RHATRDPIKPMCLIDAYLSQLEKE---DNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLP--CMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFLDEDGKFVK--PDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFE 477
BLAST of Cytochrome P450 2W1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011254.1 (pep scaffold:Pmarinus_7.0:GL479221:5463:6953:-1 gene:ENSPMAG00000010227.1 transcript:ENSPMAT00000011254.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 87.8113 bits (216), Expect = 1.312e-18 Identity = 96/431 (22.27%), Postives = 182/431 (42.23%), Query Frame = 2
Query: 389 IKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGV-LSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIIT---SSNLTFSNAVFPLTNVPLLKYCVP--SVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTN 1660
I +N + E+ K YG + + + + V++ E E + G + RP+T ++ +++ G+ L+ G W R+ L D I+ K L+ + + ++ II ++ D+D+E+ +K ++ + + L VFP LLK P V I + +N + + +K+ +L S YL Q+ K + + + I+ ++ G +T + TL W L + IQ + EI+ V + +D+ LPYL + I E+ R+ ++P V H K++ F+ Y + ++ + ++ H+ W +KF D F++ + I+ + F PF G R C+GESLA+ E+ L +L+ H++ N
Sbjct: 55 ICNNPHIAMQELAKKYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTKLTQNIGIALAPYGDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIETFKQETSAFDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFPF----LLKLPGPWQKVFHIHSKLQCLLNDIVSEHRATKDQHNPRDLIDS-----YLAQIDKEK--DNPNSSFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPP--CMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFLDKDGQCIQ--SDAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYWPN 470
BLAST of Cytochrome P450 2W1 vs. Ensembl Sea Lamprey
Match: cyp1d1 (cytochrome P450, family 1, subfamily D, polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-041114-179]) HSP 1 Score: 80.1073 bits (196), Expect = 4.332e-16 Identity = 55/192 (28.65%), Postives = 102/192 (53.12%), Query Frame = 2
Query: 1076 LTKVYEEEHQ----HLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKI-KHLQENFYPFGTGKRNCIGESLARKEVLLTLVALI 1633
+ E+EH L+D + DI GAG DT+ L WC L L +Q+KL+ EI+E + F D++ L + +F+ E+ R+ +P T+ H ++++ +G + + + + + NH+ +W + ++F DRF+ + +++ K + E FG GKR C+G+ +AR+E+ + LV L+
Sbjct: 304 IAMCAEQEHALREVGLSDERVVATALDIFGAGFDTIITGLTWCLLYLCIHPDVQHKLQREIDETIGRDRTPRFE--DRANLRRVEAFLTEMFRHSAFVPFTIPHSTTQDVVLNGMFIPRDTCVFVNLHQVNHDPTVWSDPERFDPDRFLSHDGKEVNKEMVEKVQIFGLGKRRCLGDMVARQELFVVLVTLL 493
BLAST of Cytochrome P450 2W1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011204.1 (pep scaffold:Pmarinus_7.0:GL477378:78074:79555:1 gene:ENSPMAG00000010177.1 transcript:ENSPMAT00000011204.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 77.7962 bits (190), Expect = 1.889e-15 Identity = 92/423 (21.75%), Postives = 175/423 (41.37%), Query Frame = 2
Query: 419 EMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGV-LSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKY---IKNVQIITSSNLTFSNAVFPLTNVPLLKYCVP--SVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPM-KNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNES 1666
E+ K YG + + + + V++ + E + G + RP+T L+ ++ G+ L+ G W R L D I+ + L+ + + +S II ++ I D+++E+ +K ++++ + + L VFP L+K P V I + + + + +K+ +L S YL + K + ++ D I ++ G +T + TL W L + IQ + EI++ V + D+ LPYL + I E+ R+ I+P V P K++ F+ Y + ++ + ++ ++ W KF D F++ + IK + F PF G C GESLA+ E+ L +L+ H++ N +
Sbjct: 61 ELAKKYGEVCTIMLGSTPVVLVSGYQAVKEVLVNRGHEFADRPITPLFTKLTHNIGIALAPYGDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIETFKQETSEFDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVFPF----LIKLPGPWQKVFHIHTKLQCLLKDIVSEHRATKDQHNPRDLIDS-----YLAHIDKEK--DNPNRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPP--CMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFLDKDGQCIK--SDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFEFYWPNSA 468
BLAST of Cytochrome P450 2W1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008590.1 (pep scaffold:Pmarinus_7.0:GL483327:8497:10357:1 gene:ENSPMAG00000007780.1 transcript:ENSPMAT00000008590.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 72.0182 bits (175), Expect = 4.122e-15 Identity = 44/148 (29.73%), Postives = 77/148 (52.03%), Query Frame = 2
Query: 1283 SYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYK-IELTNESKLNFEEILNGENGLVFAP 1720
S SD+ +LP+ + + EV R+ +I+P + H ++ +F GY L E I+ + + W ++F F+ +++ K + ++ F PF G+R C+GE LA+ E+ L LVAL+ + + LN L +NG+ AP
Sbjct: 7 SLSDREKLPFTNAVLYEVQRFASIVPLALPHATTRDALFQGYFLPEGTIVFAVLDSVLKDPSQWETPEEFNPSHFL-DRDGKFRK-RDAFLPFSAGRRVCLGEQLAKAELFLFLVALLQKFSFVAPRGPDSLN----LAPQNGITVAP 148
BLAST of Cytochrome P450 2W1 vs. Ensembl Nematostella
Match: EDO40300 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7U4]) HSP 1 Score: 105.145 bits (261), Expect = 4.340e-24 Identity = 106/447 (23.71%), Postives = 191/447 (42.73%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRR---GVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYI---DRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKK--YIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFI-RNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAP 1720
F + K YG I+ + ++ +VL ++ EA +GRPL + + + +R + + D G+ W ++RKL + ++ + R ++VI E + L + D P I + F + +I +F D +D + ++ YI + + + FP P L Y V IK+ I+ + E E + N + + KQ + + + +H + I + AGS+T TL+W L +Q +L EI++ + + S + +P L +F E R ++P ++ H+ + GY++ + + + ++ +H+ IW D F DRF++ K + + F PFG G R C+GE LAR E+ L L L+ H+ E N L G+ G+V P
Sbjct: 24 FAALEKTYGKIFRVYLAHKPIIVLSGDAIK-EALVRQPRNFAGRPLLPITEEIVDKRWGPALFAMDYGERWRIFRKLGHSTI-KVYGEDR-LQEVINEEVSELCKRLEESDEKP--IDITKQFGTAVTNVICTKIFGNRYDINDPEFQRLYYINDKSTRLNIGEGWLKEAFPFLK-PFLPYSQ-QVKEIKELDQERFVIMRAKYDEHVETFDPNHIRDYTDALLKAKQ-EAEEEDKSSKEHFGEGPIIMAGLVTLFLAGSETTTTTLSWAIAYLLHNPGVQARLHKEIDQVI--GKDVSPKLSQRKNIPVLEAFTAETQRLSNLVPLSLPHKTTSDCTLLGYEIAKGTTVFTNLWSLHHDPSIWKEPDTFNLDRFLDAKGKFQAPVGGTFLPFGAGPRVCLGEVLARSELFLFLATLLQHF--EFVNPLGCPLPS-LEGDMGVVLHP 457
BLAST of Cytochrome P450 2W1 vs. Ensembl Nematostella
Match: EDO41250 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S508]) HSP 1 Score: 105.145 bits (261), Expect = 5.604e-24 Identity = 107/436 (24.54%), Postives = 204/436 (46.79%), Query Frame = 2
Query: 377 NLFRIKSNENKFFM-EMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMT-LSGRPLTELYKYVSK--RRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRI-KKAMDNNVNILTELWKESK----ENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKN-LIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE 1651
NL I +++ ++ K YG+I+ +I N R+V + + E M L+GRP T + +S+ + VL + V RK+ L K E++ E KL ++ +I + +F + II + + + DD ++ ++I S + S ++ L P L + S R K ++ +L + + E K E+C + ++ F +L++ + ++ + D + +D+ G +T + TL+W L + +Q +L+++I++F+ + + +DK LPY+ + I EV R T++P V H+ N + GY + ++ II+ + + +H+ WPN DKF DRF+ + Q ++ PF G+R C+GESLA+ E+ L + L+ + +E
Sbjct: 40 NLLSITGSDSHIAAAKLAKTYGDIFMLKIFNDRFVFVSSGAGAREVLMGKRMNDLAGRPQTFTFNLLSRGAKDIVLGDYSRHLVWRRKIVHLGLRMYFPKLE--ENIAWEVSKLEGKLMEDIGAAIHSKEVFLLLITNIISSFLLGKSYEPDDPDFLTTLEFIRI--GSQVPVSGSI--LDKFPFLYHLPISESRFYKNVVEPRDRLLDKFFLEHKSTFSEDCIRDLTDA-----FLKAKLEVEREDKKAIGEVTDDHITMLMTDVYVGGLETTSTTLSWLAAYLINYPLVQTRLQTDIDDFIGSRWPVL---ADKPNLPYMEATIAEVLRIATVLPMGVPHKATTNNVPLMGYNIPKDTIIVMNLWAIHHDPREWPNPDKFDPDRFINEDGKFEVPGQRSYLPFSAGRRVCVGESLAKIELFLVMTRLLQQFTLE 461
BLAST of Cytochrome P450 2W1 vs. Ensembl Nematostella
Match: EDO48774 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI92]) HSP 1 Score: 104.76 bits (260), Expect = 5.806e-24 Identity = 109/482 (22.61%), Postives = 208/482 (43.15%), Query Frame = 2
Query: 368 LFKNLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRK----LTTKALHEISHKTRGFEDVITENIKLLLNYI------DRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVL-RIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLT-KVYEEEHQH------------LNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLK 1738
L NL + S + + IYG I++ + +Q VVL + E+ EA G +GRP + S+ + L R+ + T E +++IT + L + D +P R F + ++ +I F ++E+ + + +++I LT ++ + PLL+Y S++ R++ A+ ++L + ++E ++ + G K LT + EE +Q L D + + +D + AGS+T L W +Q + +I++ + I ++ D+ +LPYL +FI EV R +I+P V H M +++ GY + + ++ + + H+ +W +F +RF++++ E F P+G G R+C GE LAR E+ L V L+ ++ + E+L+GE G+ P ++
Sbjct: 8 LIGNLHLLSSKPHLDLARLGNIYGPIYTLNMGSQLAVVLNSYEIAKEALMKRGNAFAGRPHHFVGSKFSRGGKGVGFQNYTPTLRRQQKTIMKTVKYFETLKTGENLQEIITNEVDYLCDLFVSHGCQDFDP---RRDMTFAAGN--VVGRITFGERFTVENEEFWQLMDSLKIFVE-GLTATSFI---DAFPLLRYFPFSLVKRVQTAVKLRDDVLNKRFREHQDRLRGD-------GMVLAKSKDLTYALIEEANQKTSRTDSQSDTLILTDDHVMMTMNDTIMAGSETPTMLLLWNIYFFVKYPDVQARAFKQIDKVISPDQPI--TWEDRKRLPYLEAFIAEVMRIISIMPLAVPHLAMVDMVLAGYHISKGTTVIVNLWAMGHDPKVWDAPMEFRPERFLDSRGGFSTASSEGFTPYGMGLRSCPGEQLARMELFLFTVRLLRMFEFRASEA----LPEMLDGEFGITIRPLPFKIR 467
BLAST of Cytochrome P450 2W1 vs. Ensembl Nematostella
Match: EDO32562 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUQ2]) HSP 1 Score: 104.76 bits (260), Expect = 9.397e-24 Identity = 113/480 (23.54%), Postives = 202/480 (42.08%), Query Frame = 2
Query: 383 FRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQI-------WVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYID---RNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAV---FPLTNVPLLK-YCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQ---------HLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKI-KHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSR 1747
FR+ + F+EM + YG ++S + ++ VVL LQ +GRP +LY R G DG I W L RK A+H+ E ++ + L+ +D P ++ F T ++I I+F N D +V+ I ++ F V + +P ++ + +P V R+ K + +L L++E+K +S G + KV EE Q + D++ ++ D+VGAG DT + TL W ++Q ++ EI+ + + + D LPY + + E+ R + P V H ++ + F GY + ++ +I + ++ N + W N D F RF++ + + + F PFG G R C G LA E++ + A++ ++ + + L GE GL P +++ +R
Sbjct: 67 FRLGPKSHLDFLEMSRNYGQVFSMYLGSRLVVVLNGMALQEALTGKLSRVFAGRP--KLYTMERCRNG---GDGLINAPYCRKWKLMRKTAITAIHKYIATQDVLESILGKVAHGLVQRLDACAETPHNVMPELKF--ATASVILGILFGENHD---------ASHVESILGTSDDFRKCVGCGLAVDFMPWMENFPIPKVNRMVKLTSDMNAVLKNLYEENK---------TSYSGRIRNLADAVIKVSEEHSQIDDDSDPKGEMADLDVVQTIVDLVGAGFDTSSLTLYWAIAYFVKYPQVQRRIHHEIDTVIGRDRIP--TLDDVKHLPYTHACLYELLRVTCLAPTAVPHSTLEEVDFRGYTIPKDTVIFANIWSLLRNEEYWQNPDVFDPMRFLDEEGRLLNPNSWPTFLPFGAGIRKCTGRELAIAELMFFITAIMQKFRFSEEGLTADHPPIDLTGEAGLTLKPADYHVIITR 519
BLAST of Cytochrome P450 2W1 vs. Ensembl Nematostella
Match: EDO41284 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S507]) HSP 1 Score: 103.605 bits (257), Expect = 1.835e-23 Identity = 104/440 (23.64%), Postives = 211/440 (47.95%), Query Frame = 2
Query: 377 NLFRIKSNENKFFM-EMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMT-LSGRPLTELYKYVSK-RRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRN-----PGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRI-KKAMDNNVNILTELWKESK----ENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKN-LIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIE 1651
NL I +++ ++ YG+I++ +I N R+V + + E M L+GRP T + ++++ + ++ D +++R+ K +H R + + ENI ++ ++R ++ + + F + II + + + DD ++ +I S L S ++ L N P L + S R KK ++ +L + + E K E+C + ++ F +L++ + ++ + D + +D+ AG +T + TL+W L + ++Q +L+++I++ + + + +DK LPY+ + I EV R T+ P + H+ N + GY + ++ II+ + + +H+ WPN DKF DRF+ + Q ++ PF G+R C+GESLA+ E+ L + L+ + +E
Sbjct: 40 NLLSITGSDSHLAAAKLANTYGDIFTLKIFNDRFVFVSSGAGAREVLMGKRMNDLAGRPQTFTFNFLTRGAKDIIFGDYSRHLVWRR---KIVHS---GLRMYFPKLEENIAWEVSKLERKLMKDVGTALHSRDEFSLLITNIISSFLLGKSFEPDDPDFLTTLEFTRI--GSQLPVSGSI--LDNFPFLVHLPISESRFYKKLVEIRDRLLDKFFLEHKSTFSEDCIRDLTDA-----FLKAKLEVEREDKKAIGEVTDDHITMLMTDVYFAGLETTSTTLSWLAAYLINYPQVQTRLQTDIDDVIGSRWPVL---ADKPNLPYMEATIAEVLRIATVAPMGLPHKATTNNVPLMGYNIPKDTIIVMNLWAIHHDPREWPNPDKFDPDRFINEDGKFEVPGQRSYLPFSAGRRVCVGESLAKIELFLVMTRLLQQFTLE 461
BLAST of Cytochrome P450 2W1 vs. Ensembl Medaka
Match: ENSORLT00000024770.2 (cytochrome P450 2J6 [Source:NCBI gene;Acc:101169416]) HSP 1 Score: 135.961 bits (341), Expect = 6.762e-34 Identity = 115/425 (27.06%), Postives = 200/425 (47.06%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKI----KKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNES 1666
F +M + YGN++SF I ++ VV+ + EA SGRP +++R+GV+ D G +W +R+ L E+ I E I+ ++ ++ N G ++ +FH+ II K++FN D++D KI + +++ +QI +A + + PL + + M+N +N+ L E K + E + YL +L+ K E Q L M F D+ AG+DT + T+ L L IQ K + EI++ +E K + S+ D+ ++PY+ + I EV R+ I+P +V H K+ GY + + +I+ + + W +F + F+ ++ E IK E F PF G R C+GE LAR E+ + +V L+ +K ++
Sbjct: 52 FEKMKESYGNVYSFFIGSRPAVVVNGLQAMKEAIMIKATDFSGRPQDMFVSDLTQRKGVILVDYGSVWRDHRRFALMTLRNFGLGKISMEERIHEEIQFTISKLEENIGKTLSPKFMFHNAASNIICKVLFNTRYDYEDGKISEIVQGFVEMLQIANGPWAMMYDAFPWIRSFPL------PFNKAFRNMENFLNLAKRLVNEHKMSRVAGE--PRDFVDSYLDELEKNKKDFSEQQLLR-MTF-----DLYIAGTDTTSNTMLAGFLYLMVYPHIQEKCQREIDQMLERKDRV--SFEDRHKMPYMQAVIHEVQRFANIVPLSVFHCTTKDSELSGYTIPKGTLIIQNMVSVLREEGQWKFPHEFNPENFLNDQGEFIK--PEAFMPFSAGPRMCLGEGLARMELFIIMVTLLRKFKFTWPEDA 458
BLAST of Cytochrome P450 2W1 vs. Ensembl Medaka
Match: ENSORLT00000017336.2 (pep primary_assembly:ASM223467v1:6:26186654:26196090:-1 gene:ENSORLG00000013826.2 transcript:ENSORLT00000017336.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 125.946 bits (315), Expect = 1.357e-30 Identity = 117/433 (27.02%), Postives = 201/433 (46.42%), Query Frame = 2
Query: 377 NLFRIKSNEN-KFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGV-LSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSN-LFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLT--NVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKV---YEEEHQHLNDMNFIRNFS-DIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYK 1645
NL + +++ K F + K YGN++S I Q VV+ + EA + G +GRP +V+++ GV L + G W +R+ L ED I E I+ + ++++ GS + +FH+ II ++++ +++DE IK IK + N +N + + ++P+L+ + K + NI +L KE KE E + YL +L+ + EE + +S D+ AG+DT + TL L L IQ + + EI+ +E K + S+ D++ +PY+ + I EV R I+P +V H MK+ Y + + +++ + + W +F + F+ K E +K E F PF G R C+GE LAR E+ LT+V L+ +K
Sbjct: 39 NLLHLSTDDPLKDFERLRKSYGNVFSVFIGPQPAVVINGLKAMKEALVNKGSDFAGRPQDLFINHVTQQLGVVLENYGTTWREHRRFALMTLRNFGLGKTSMEDRIHEEIQQTIKTLEKSIGSTLSPQVIFHNAASNIICQVLYGKRFEYNDEMIKVIIKCF----TDNAKMTNGPWAMIYDSLPILRKLPLPFRKAFKNYETCKNIAFDLLKEHKETKVPGE--PRDFVDCYLDELEKKSADSSFSEER--------LAGYSLDLYFAGTDTTSNTLLTGFLYLVGHPHIQERCQQEIDLVLEGKDQV--SFEDRNNMPYMQAVIHEVQRIANIVPFSVFHATMKDTELMEYSIPKGTMVIQNMKSVLTEEGQWKFPHEFNPENFLNEKGEFVK--PEAFMPFSAGPRVCLGEGLARMELFLTMVTLLRKFK 453
BLAST of Cytochrome P450 2W1 vs. Ensembl Medaka
Match: ENSORLT00000017318.2 (pep primary_assembly:ASM223467v1:6:26173766:26186815:-1 gene:ENSORLG00000013811.2 transcript:ENSORLT00000017318.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 117.087 bits (292), Expect = 1.593e-27 Identity = 108/428 (25.23%), Postives = 191/428 (44.63%), Query Frame = 2
Query: 398 NENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSD-GQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSN-LFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLT--NVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNES 1666
N K F + YGN++S + + V++ + EA +GRP VSKR+GV+ +D G+ W +R+ L + E+ I+E I+ + ++ N G + + +FH+ II +++F ++DDE IK VQ T N +N + + ++PL++ K + V++ T L E KE + + YL +++ + ++ I D+ AG+DT + TL L + IQ+K + EI+ +E K + ++ D+ +PY+ + I EV R +P +V H K GY + + +I+ + + W F + F+ K E +K E F PF G R C+GE LAR E+ + +V L+ +K ++
Sbjct: 47 NPLKDFDRLRNSYGNVYSLFLGPKPAVIINGFKAMKEAMVIKATDFAGRPQDLFVNDVSKRKGVILADYGESWRDHRRFALMTLRNFGLGKKSMEERISEEIQHTIKTLENNIGKLFSPQIMFHNAASNIICQVLFGKRFEYDDEIIKTI---VQCFTR-NSKIANGPWAMIYDSIPLIRKLPLPFREAFKNAEICVDVGTHLVNEHKETRIPGK--PRDFVDCYLDEME----KRGDDSSFSEDQLIIYALDLHFAGTDTTSNTLLTGFFYLINYPHIQDKCQQEIDRVLEEKQQV--TFEDRHNMPYMQAVIHEVQRIANTVPLSVFHSTTKETELMGYTIPKGTMIIQNMGSVLREDGQWKFPHDFNPENFLNEKGEFVK--PEAFMPFSAGPRMCLGEGLARMELFIIMVTLLRKFKFTWPEDA 460
BLAST of Cytochrome P450 2W1 vs. Ensembl Medaka
Match: ENSORLT00000019638.2 (cytochrome P450 2K1 [Source:NCBI gene;Acc:101157991]) HSP 1 Score: 114.005 bits (284), Expect = 1.820e-26 Identity = 111/446 (24.89%), Postives = 194/446 (43.50%), Query Frame = 2
Query: 419 EMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEI-LNGENGLVFAPFCHNL 1735
E K YG +++ ++ VVL + A + R + + + ++K GVL S+G IW R+ L + + ED ITE + LL + G + T+ + II +V+ ++DD K + +N+Q+ S L N VP L V S + + N ++ KE ++ + F +K L K + ND N + + AG++T + TL W LL+A KIQ++++ E+ + + V SD+ LP+ + I E+ R +I+P + H+ K++ F GY + + + + H+A+ W F F++ + +K +E F PF G+R C+GESLAR E+ + L+ ++ T ++ EE+ L G+ P H L
Sbjct: 67 EFSKTYGPVFTVFFGGEKVVVLAGYKTVKNALVNHDEEFGERAIPPIIQELNKGLGVLWSNGDIWRDIRRFALTNLRDFGMGKKACEDKITEECQYLLEVFKKFKGNAFDTTKPLNYAVSNIICSMVYGSRFEYDDPKFTSMVDRTNRNIQLSGSPTLQAYNM------VPWLFKWVASRREVHECAAANRKQNQSIFSHLKETLNP-QMCRGFVDAFLVKGQTLEK-SGVTNSAFNDENLLMTVIHLFAAGTETTSTTLRWGLLLMAKYPKIQDQVQDELRRVIGDRMV---QVSDRKNLPFTDAVIHEIQRLASIVPTALPHKTSKDVTFQGYFIKKGTTVFPLLTSVLHDANEWEKPHTFYPAHFLDKDGKFVK--REAFIPFSAGRRICLGESLARMELFMFFTTLLQNFC--FTPPPGVSKEELSLTPCGGITVGPVPHKL 497
BLAST of Cytochrome P450 2W1 vs. Ensembl Medaka
Match: ENSORLT00000020799.2 (cytochrome P450 2J6 [Source:NCBI gene;Acc:101155419]) HSP 1 Score: 112.849 bits (281), Expect = 4.585e-26 Identity = 112/443 (25.28%), Postives = 200/443 (45.15%), Query Frame = 2
Query: 413 FMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLT-IIFKIVFNINTDFDDEKIKKYI----KNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNV-NILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTV-HRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAP 1720
F ++ YG+++S R + VVL + EA G ++ RP L ++K GV+ S+G W R+ L + E VI + R G +L + T++ II +VF ++ D+K KK + + +QI S N+ L+ C+P + + + V + + E KE K++ + + ++ +FYL ++Q TK +E ++ N I D+ AGS+T + TL W L +A +IQ K+++EI++ + D+++LPY + I EV R I+P ++ H K++ G+ + + +I+ + + + W F F+ + +K + F PF GKR C+GE+LAR E+ L + + H+ + E +L+ GL AP
Sbjct: 89 FSKLAAEYGDLYSLRFGQRWTVVLNGHKALKEALVTKGDSVVDRPHLPLQDEIAKGLGVIFSNGANWTEQRRFALSTLRYFGFGKKSLEPVILNEFAHCAEELKRFKGEPLDPHLIINNTVSNIICHLVFGHRFNYGDKKFKKLMLLFDRALQIEASIWAQLYNS------FTLIMRCLPGPHKTLQHIWREVQDFIGEELKEHKKSWDPS--DARDYIDFYLTEIQKTK--GQEGSTFDEENLIMCVLDLFVAGSETTSTTLRWAFLYMAKYPEIQEKVQAEIHKVIGKSRPP--CMEDRAELPYTDAVIHEVQRIGNIVPLSLPHATNKDVQLGGFTIPKGVLIIPNLTSVLFDEKEWETPHAFNPGHFLNKDGKFVK--RGAFIPFSAGKRLCLGENLARMELFLFFTSFMQHFSFSMPA----GVEPVLDYRAGLTLAP 513
BLAST of Cytochrome P450 2W1 vs. Planmine SMEST
Match: SMESG000059212.1 (SMESG000059212.1) HSP 1 Score: 918.302 bits (2372), Expect = 0.000e+0 Identity = 481/484 (99.38%), Postives = 482/484 (99.59%), Query Frame = 2
Query: 305 YSFKDXXXXXXXXXXXXXXVVLFKNLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSRISN 1756
YSFKDPPGPIGIPFIGIFPVVLFK LFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNP SIRTSNLFHSMTLTIIFKIVFNI+TDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVAATLAWCCLLLADRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSRISN
Sbjct: 21 YSFKDPPGPIGIPFIGIFPVVLFKKLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPDSIRTSNLFHSMTLTIIFKIVFNIDTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVAATLAWCCLLLADRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSRISN 504
BLAST of Cytochrome P450 2W1 vs. Planmine SMEST
Match: SMESG000048645.1 (SMESG000048645.1) HSP 1 Score: 848.195 bits (2190), Expect = 0.000e+0 Identity = 454/484 (93.80%), Postives = 460/484 (95.04%), Query Frame = 2
Query: 305 YSFKDXXXXXXXXXXXXXXVVLFKNLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSRISN 1756
YSFKDPPGPIGIPFIGIFPVVLFK LFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQT+AFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKA + K E++K+ NP SIRTSNLFHSMTLTIIFKIVFNI+TDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVAATLAWCCLLLADRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENK EKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSRISN
Sbjct: 21 YSFKDPPGPIGIPFIGIFPVVLFKKLFRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTKAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKAYMKYPIKQ--------EDLKI-------NPDSIRTSNLFHSMTLTIIFKIVFNIDTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVAATLAWCCLLLADRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKGEKIKHLQENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSRISN 489
BLAST of Cytochrome P450 2W1 vs. Planmine SMEST
Match: SMESG000023528.1 (SMESG000023528.1) HSP 1 Score: 173.711 bits (439), Expect = 2.115e-47 Identity = 137/461 (29.72%), Postives = 234/461 (50.76%), Query Frame = 2
Query: 392 KSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLT-ELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFED-VITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQII-TSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTEL--WKESKENCETNELES-----SSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHL---QENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNL 1735
K +++K + EM + YG +WS ++ + R +V + EL E+ G S RP + YVSK+ G++ G+ W +RK T K +H++ ED V+ E+ KLL +++ L+ + II +++ N + ++DD+K IKN+Q+I N+ + + N + + SV + MDN L EL W ES+ + + + S I E YL + + E + IRN DI GAG DT L WC L+L + Q ++R+EI KS +++ + +F++E RYF +I R VH K + F G+ L+ D+++ D T + + DIW + ++F RF++ + +HL ++ FG GKR+C+GE+LAR E+ + L+++I ++I+LT + N I++G GL++AP H +
Sbjct: 49 KYSQSKCYSEMKEKYGALWSRKLFHIREIVFASYELIYESLVIQGTQFSNRPKDLPIMDYVSKKGGIIFIGGKYWKAHRKDTLKIMHKLGMNNLTIEDKVVQESEKLLQEIFKSANKPVKSDKLYSKPVMNIICQLMLNRSFEYDDQKFINVIKNIQVIGQDGNVNLLFFMRSIINFWIFRETFKSV---RIYMDN----LEELEEWVESQLDATSEKFNPEFDNPSCILEHYLVLQKQQESNGESSDLYSKHQIIRNCFDIYGAGIDTTTHMLCWCTLMLGLKPDFQTRIRNEIKA---NKSNSPMNFNTTKSFHFFKAFLDECFRYFPVIQRAVHAVEKPIDFKGFHLVPRDLLMMDFKTLSKDPDIWKDPEEFDPFRFMD----ETRHLYNPNKHLIAFGIGKRSCMGENLARCELTIILLSIIQTFEIKLTQNTLENINLIISGTEGLIYAPLEHEI 495
BLAST of Cytochrome P450 2W1 vs. Planmine SMEST
Match: SMESG000023530.1 (SMESG000023530.1) HSP 1 Score: 171.785 bits (434), Expect = 1.197e-46 Identity = 135/461 (29.28%), Postives = 233/461 (50.54%), Query Frame = 2
Query: 392 KSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLT-ELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFED-VITENIKLLLNYIDRNPGSIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQII-TSSNLTFSNAVFPLTNVPLLKYCVPSVLRIKKAMDNNVNILTEL--WKESKENCETNELES-----SSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHLQE---NFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNL 1735
K +++K + EM + YG +WS ++ + + +V + EL E+ G S RP + YVSK+ G++ G+ W +RK T K +H++ ED V+ E+ KLL + + L+ + II +++ N + ++DD+K IKN+Q+I N+ F + + N + + SV + MDN L EL W ES+ + + + S I E YL + + E + IRN DI AG DT L WC L+L + Q ++R+EI KS +++ + +F++E RYF +IPR H K + F G+ L+ D+++ D + + DIW + ++F RF++ + +HL + + FG GKR+C+GE+LAR E+ + L+++I +++I+LT + N I++G GL++AP H +
Sbjct: 49 KYSQSKCYSEMKEKYGALWSRKLFHIKEIVFASYELIYESLVIHGTQFSNRPKDLPILDYVSKKGGIIFIGGKYWKAHRKDTLKIMHKLGMNNLTIEDKVVQESEKLLQEIFKSANKPVESDKLYSKPVMNIICQLMLNRSFEYDDQKFINVIKNIQVIGQDGNVHFLFYMRSIINFWIFRETFKSV---RIFMDN----LEELEEWVESQLDATSEKFNPEFDNPSCILEHYLVLQKQQESNGESSDLYSKHQIIRNCFDIYSAGIDTTTHMLCWCTLMLGLKPDFQTRIRNEIKA---NKSNSPMNFNTTKSFHFFKAFLDECFRYFPVIPRIAHAVEKPIDFKGFHLVPRDLLMMDFKAMSKDPDIWKDPEEFDPFRFMD----ETRHLHKPNKHLIAFGIGKRSCMGENLARCELTIILLSIIQNFEIKLTQNTLENINLIISGTEGLIYAPLEHEI 495
BLAST of Cytochrome P450 2W1 vs. Planmine SMEST
Match: SMESG000063883.1 (SMESG000063883.1) HSP 1 Score: 170.244 bits (430), Expect = 5.230e-46 Identity = 131/460 (28.48%), Postives = 227/460 (49.35%), Query Frame = 2
Query: 383 FRIKSNENKFFMEMHKIYGNIWSFRIINQRYVVLGAPELQTEAFKHSGMTLSGRPLTELYKYVSKRRGVLSSDGQIWVLYRKLTTKALHEISHKTRGFEDVITENIKLLLNYIDRNPG-SIRTSNLFHSMTLTIIFKIVFNINTDFDDEKIKKYIKNVQIITSSNLTFSNAVFPLTNVPLL-KYCVPSVLRIKKAMDNNVNILTELWKESKENCETNELESSSIGEFYLKQLQLTKVYEEEHQHLNDMNFIRNFSDIVGAGSDTVXXXXXXXXXXXXDRVKIQNKLRSEINEFVEVKSVIFFSYSDKSQLPYLCSFIEEVHRYFTIIPRTVHRPMKNLIFHGYKLLENDIILGDSYTSNHNADIWPNADKFIFDRFVENKEEKIKHL-QENFYPFGTGKRNCIGESLARKEVLLTLVALICHYKIELTNESKLNFEEILNGENGLVFAPFCHNLKFSRIS 1753
F +E ++F +M + YG+IWS + QR + L + ++ EAF +GM SG L + +RG+L DG IW R L KAL + T E + E L+ I + G I F II + FN + +D K +KY+ ++ +S++ ++P + L ++ P V A+ NN ++ + S+ + + ++ K + ++ ++ N I+ +D+ AG++T L +CCLLL ++Q+ LR+E+ VE + I + + K++ P L SFI EVHR+ ++P+ HR MK IF G++ +D++ D + + + + N KF RF++ E + K++ ++ FG G+R CIGESLA E+ L +I ++I L+NE+ +F +I GE G++ H L F +S
Sbjct: 50 FMTNVSECEYFKQMRQKYGSIWSIETVGQRIITLASFDIVHEAFVENGMLFSGCAQNSLVELYGGKRGILFVDGAIWKQNRHLAIKALTTMGMGTSALEKLNCEQADCLIKEIKQKSGIQIDPRKEFVKAIANIINIVNFNEPNNENDPKFEKYMLCLEKFANSHIKHIIFIWPSFFLSKLGRFLFPKVEEYVNAIYNNRRLVADKCM-SRLKVFNQSSDLKCVFDYIWKNEDFIEDLNDQSFNVKIFNVIQIMTDLQNAGTETTYNLLRFCCLLLGRYPEVQDDLRNELQNLVEDSTQI--TLNLKNKCPKLLSFIGEVHRFCNLVPKVGHRVMKKFIFRGFEFDTSDMVFADFNSIMFDENHFDNPQKFDPYRFLD--ETRTKYIPSQHLIGFGIGRRTCIGESLANMEIFFLLSRIIFEFQISLSNETVEHFAKIFEGEIGIMRTSLYHELVFHSVS 504 The following BLAST results are available for this feature:
BLAST of Cytochrome P450 2W1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Cytochrome P450 2W1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cytochrome P450 2W1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30016752 ID=SMED30016752|Name=Cytochrome P450 2W1|organism=Schmidtea mediterranea sexual|type=transcript|length=1782bpback to top protein sequence of SMED30016752-orf-1 >SMED30016752-orf-1 ID=SMED30016752-orf-1|Name=SMED30016752-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=505bp MIYIILILLLVICLLINKLIYSFKDPPGPIGIPFIGIFPVVLFKNLFRIKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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