T-cell acute lymphocytic leukemia protein 1

Overview


Name	T-cell acute lymphocytic leukemia protein 1
Smed ID	SMED30016749
Length (bp)	408

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of T-cell acute lymphocytic leukemia protein 1 (SMED30016749) t-SNE clustered cells

Violin plots show distribution of expression levels for T-cell acute lymphocytic leukemia protein 1 (SMED30016749) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of T-cell acute lymphocytic leukemia protein 1 (SMED30016749) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016749

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30016749	SMESG000067729.1	dd_Smed_v4_16646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016749	SMESG000067729.1	dd_Smed_v4_16646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30016749	SMESG000067729.1	dd_Smed_v6_16646_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
parenchyma	SMED30016749	SMESG000067729.1	KF487105	smed_ncbi_20200123	PMID:24173799 Cowles et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Human
Match: TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor [Source:HGNC Symbol;Acc:HGNC:11556])

HSP 1 Score: 78.1814 bits (191), Expect = 1.585e-17
Identity = 36/58 (62.07%), Postives = 45/58 (77.59%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q    
Sbjct:  193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEG 250

[Close]

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q    
Sbjct:  193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEG 250

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Human
Match: TAL2 (TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557])

HSP 1 Score: 71.633 bits (174), Expect = 1.060e-16
Identity = 33/55 (60.00%), Postives = 44/55 (80.00%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQS 347
            N+RER RQQ+VN+AF  LR+++P HPPDKKLSK+E LR A++YI  L ++L  QS
Sbjct:    8 NTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQS 62

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Human
Match: LYL1 (LYL1 basic helix-loop-helix family member [Source:HGNC Symbol;Acc:HGNC:6734])

HSP 1 Score: 74.3294 bits (181), Expect = 2.684e-16
Identity = 37/64 (57.81%), Postives = 48/64 (75.00%), Query Frame = 3

Query:  156 KSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQS 347
            + VA R   NSRER RQQ+VN AF +LR++LP HPPD+KLSK+E+LR A+KYI  L  +L  Q+
Sbjct:  147 QKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQA 210

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Human
Match: NHLH1 (nescient helix-loop-helix 1 [Source:HGNC Symbol;Acc:HGNC:7817])

HSP 1 Score: 60.077 bits (144), Expect = 7.108e-12
Identity = 30/56 (53.57%), Postives = 40/56 (71.43%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILN 338
            R ++ +RER R ++ N AF +LR++LP  PPDKKLSK EILR AI YI  L  +L+
Sbjct:   77 RTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 132

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Celegans
Match: hlh-15 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q18590])

HSP 1 Score: 53.5286 bits (127), Expect = 3.040e-10
Identity = 28/55 (50.91%), Postives = 37/55 (67.27%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R  + +RER R +S N AF+ LR +LP  P +KKLSK EILR +I YI  L+ +L
Sbjct:   34 RNLHATRERIRVESFNMAFSQLRALLPTLPVEKKLSKIEILRFSIAYISFLDNLL 88

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Celegans
Match: lin-32 (pep chromosome:WBcel235:X:2229208:2230122:-1 gene:WBGene00003018.1 transcript:T14F9.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-32)

HSP 1 Score: 52.373 bits (124), Expect = 2.340e-9
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNE 359
            R + N RER R  ++N A+++LR++LP     KKLSK E L+ A KYI  L +IL  Q + NE
Sbjct:   74 RSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQILK-QDSKNE 135

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Celegans
Match: hlh-13 (Helix-loop-helix protein 13 [Source:UniProtKB/Swiss-Prot;Acc:Q20561])

HSP 1 Score: 50.447 bits (119), Expect = 1.681e-8
Identity = 24/55 (43.64%), Postives = 38/55 (69.09%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R++ + RER+R  S+N AF +LR  +P  P +K+LSK + L  AI YI +L+++L
Sbjct:   43 RQTASIRERKRMCSINVAFIELRNYIPTFPYEKRLSKIDTLNLAIAYINMLDDVL 97

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Celegans
Match: hlh-19 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q20941])

HSP 1 Score: 45.8246 bits (107), Expect = 3.594e-7
Identity = 30/64 (46.88%), Postives = 39/64 (60.94%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYI----RILEEILNFQSN 350
            R+  N+RER RQ+S+  AFN LR  LP    D+K SK E L+ A +YI    RILE+ +   SN
Sbjct:    3 RERANARERCRQKSIGNAFNMLRNHLPKQLRDRKPSKAETLKSAAQYISHLLRILEKEIENSSN 66

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Celegans
Match: hlh-6 (Helix-loop-helix protein 6 [Source:UniProtKB/Swiss-Prot;Acc:Q10007])

HSP 1 Score: 44.669 bits (104), Expect = 4.541e-6
Identity = 27/79 (34.18%), Postives = 44/79 (55.70%), Query Frame = 3

Query:   99 PISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            P + ++T   P+ L        +     N RER R ++VN  +  LR+ LP H  +K++SK + LR AI+YI+ L+ +L
Sbjct:  151 PFAPEATVPLPVELEDQYGPYSSSVWKRNERERCRVRNVNDGYERLRKHLPVHFDEKRISKVDTLRLAIRYIKHLDNLL 229

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Fly
Match: HLH3B (gene:FBgn0011276 transcript:FBtr0070506)

HSP 1 Score: 79.337 bits (194), Expect = 4.201e-18
Identity = 35/54 (64.81%), Postives = 46/54 (85.19%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQ 344
            N+RER RQQ+V+ AF +LR+++P HPPDKKLSK+EILR AIKYI++L  IL +Q
Sbjct:  171 NTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQ 224

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Fly
Match: ato (gene:FBgn0010433 transcript:FBtr0081828)

HSP 1 Score: 59.3066 bits (142), Expect = 4.648e-11
Identity = 28/55 (50.91%), Postives = 38/55 (69.09%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R + N+RER R Q++N AF+ LRQ LPC   D++LSKHE L+ A  YI  L ++L
Sbjct:  257 RLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLL 311

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Fly
Match: HLH4C (gene:FBgn0011277 transcript:FBtr0331163)

HSP 1 Score: 57.7658 bits (138), Expect = 5.654e-11
Identity = 28/55 (50.91%), Postives = 39/55 (70.91%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R ++ +RER R ++ N +F +LR++LP  PPDKKLSK EIL+ AI YI  L  +L
Sbjct:  110 RTAHATRERIRVEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIAYLNHVL 164

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Fly
Match: HLH4C (gene:FBgn0011277 transcript:FBtr0070691)

HSP 1 Score: 57.3806 bits (137), Expect = 6.058e-11
Identity = 28/55 (50.91%), Postives = 39/55 (70.91%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R ++ +RER R ++ N +F +LR++LP  PPDKKLSK EIL+ AI YI  L  +L
Sbjct:  110 RTAHATRERIRVEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIAYLNHVL 164

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Fly
Match: Fer1 (gene:FBgn0037475 transcript:FBtr0081567)

HSP 1 Score: 56.9954 bits (136), Expect = 1.922e-10
Identity = 30/67 (44.78%), Postives = 41/67 (61.19%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLT 371
            R++ N RER R QS+N AF  LR  +P  P +K+LSK + L+ AI YI  L E++    N NE  L+
Sbjct:   83 RQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVKKDKNGNEPGLS 149

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Zebrafish
Match: CABZ01066694.1 (pep chromosome:GRCz11:6:168962:172992:1 gene:ENSDARG00000110178.1 transcript:ENSDART00000182631.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01066694.1)

HSP 1 Score: 81.6481 bits (200), Expect = 3.226e-20
Identity = 40/68 (58.82%), Postives = 52/68 (76.47%), Query Frame = 3

Query:  162 VAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEIN 365
            +A R   NSRER RQQ+VN AF++LR+++P HPPD+KLSK+EILR A+KYI  LE++LN QS   E  
Sbjct:   35 LARRVFTNSRERWRQQNVNGAFSELRKLIPTHPPDRKLSKNEILRLAMKYIDFLEQLLNDQSQPEETG 102

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Zebrafish
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:NCBI gene;Acc:30766])

HSP 1 Score: 78.5666 bits (192), Expect = 7.771e-18
Identity = 36/56 (64.29%), Postives = 46/56 (82.14%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSN 350
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q +
Sbjct:  191 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQDD 246

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Zebrafish
Match: tal2 (T-cell acute lymphocytic leukemia 2 [Source:NCBI gene;Acc:394239])

HSP 1 Score: 71.2478 bits (173), Expect = 1.173e-16
Identity = 32/56 (57.14%), Postives = 43/56 (76.79%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSN 350
            N+RER RQ +VNTAF +LR+++P HPP+KKLSK+EILR A++YI  L  +L  Q  
Sbjct:    8 NTRERWRQHNVNTAFAELRKLIPTHPPEKKLSKNEILRLAMRYINFLVTLLESQGG 63

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Zebrafish
Match: nhlh2 (nescient helix loop helix 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1809])

HSP 1 Score: 60.8474 bits (146), Expect = 1.458e-12
Identity = 30/57 (52.63%), Postives = 40/57 (70.18%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNF 341
            R ++ +RER R ++ N AF +LR++LP  PPDKKLSK EILR AI YI  L  +L+ 
Sbjct:   66 RSAHATRERIRVEAFNVAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 122

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Zebrafish
Match: atoh7 (atonal bHLH transcription factor 7 [Source:NCBI gene;Acc:58216])

HSP 1 Score: 60.4622 bits (145), Expect = 3.321e-12
Identity = 29/61 (47.54%), Postives = 41/61 (67.21%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNH 353
            R + N+RER+R Q +NTAF+ LR+++P    DKKLSK+E L+ A+ YI  L  IL+    H
Sbjct:   30 RMAANARERKRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALNRILSDAGRH 90

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Xenopus
Match: TAL2 (TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557])

HSP 1 Score: 72.0182 bits (175), Expect = 7.088e-17
Identity = 33/54 (61.11%), Postives = 44/54 (81.48%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQ 344
            N+RER RQQ+VN+AF +LR+++P HPPDKKLSK+E LR A++YI  L +IL  Q
Sbjct:    8 NTRERWRQQNVNSAFAELRKLIPTHPPDKKLSKNETLRLAMRYINFLIDILGDQ 61

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Xenopus
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:NCBI gene;Acc:100196924])

HSP 1 Score: 75.8702 bits (185), Expect = 1.375e-16
Identity = 35/58 (60.34%), Postives = 45/58 (77.59%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++L+ Q    
Sbjct:  266 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLDDQEEEG 323

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Xenopus
Match: sowahc (sosondowah ankyrin repeat domain family member C [Source:Xenbase;Acc:XB-GENE-6040120])

HSP 1 Score: 73.559 bits (179), Expect = 7.645e-16
Identity = 37/61 (60.66%), Postives = 46/61 (75.41%), Query Frame = 3

Query:  162 VAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQ 344
            VA R   NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A++YI  L  +L  Q
Sbjct:  212 VARRVFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMRYITFLVTLLGDQ 272

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Xenopus
Match: sowahc (sosondowah ankyrin repeat domain family member C [Source:Xenbase;Acc:XB-GENE-6040120])

HSP 1 Score: 73.559 bits (179), Expect = 7.992e-16
Identity = 37/63 (58.73%), Postives = 46/63 (73.02%), Query Frame = 3

Query:  162 VAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSN 350
            VA R   NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A++YI  L  +L  Q  
Sbjct:  242 VARRVFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMRYITFLVTLLGDQHG 304

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Xenopus
Match: sowahc (sosondowah ankyrin repeat domain family member C [Source:Xenbase;Acc:XB-GENE-6040120])

HSP 1 Score: 73.559 bits (179), Expect = 8.264e-16
Identity = 37/63 (58.73%), Postives = 46/63 (73.02%), Query Frame = 3

Query:  162 VAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSN 350
            VA R   NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A++YI  L  +L  Q  
Sbjct:  242 VARRVFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMRYITFLVTLLGDQHG 304

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Mouse
Match: Tal2 (T cell acute lymphocytic leukemia 2 [Source:MGI Symbol;Acc:MGI:99540])

HSP 1 Score: 74.3294 bits (181), Expect = 7.129e-18
Identity = 35/57 (61.40%), Postives = 44/57 (77.19%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNH 353
            N+RER RQQSVN AF  LR+++P HPPDKKLSK+E LR A++YI  L ++L  QS H
Sbjct:    8 NTRERWRQQSVNNAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLH 64

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Mouse
Match: Tal1 (T cell acute lymphocytic leukemia 1 [Source:MGI Symbol;Acc:MGI:98480])

HSP 1 Score: 77.7962 bits (190), Expect = 1.590e-17
Identity = 36/58 (62.07%), Postives = 45/58 (77.59%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q    
Sbjct:  193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEG 250

[Close]

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q    
Sbjct:  193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEG 250

[Close]

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q    
Sbjct:  193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEG 250

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Mouse
Match: Lyl1 (lymphoblastomic leukemia 1 [Source:MGI Symbol;Acc:MGI:96891])

HSP 1 Score: 74.3294 bits (181), Expect = 7.275e-17
Identity = 37/64 (57.81%), Postives = 47/64 (73.44%), Query Frame = 3

Query:  156 KSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQS 347
            + VA R   NSRER RQQ VN AF +LR++LP HPPD+KLSK+E+LR A+KYI  L  +L  Q+
Sbjct:   73 QKVARRVFTNSRERWRQQHVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQT 136

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. UniProt/SwissProt
Match: sp|Q62282|TAL2_MOUSE (T-cell acute lymphocytic leukemia protein 2 homolog OS=Mus musculus OX=10090 GN=Tal2 PE=4 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 4.987e-17
Identity = 35/57 (61.40%), Postives = 44/57 (77.19%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNH 353
            N+RER RQQSVN AF  LR+++P HPPDKKLSK+E LR A++YI  L ++L  QS H
Sbjct:    8 NTRERWRQQSVNNAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLH 64

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. UniProt/SwissProt
Match: sp|O93507|TAL1_DANRE (T-cell acute lymphocytic leukemia protein 1 homolog OS=Danio rerio OX=7955 GN=tal1 PE=1 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 5.866e-17
Identity = 36/56 (64.29%), Postives = 46/56 (82.14%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSN 350
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q +
Sbjct:  191 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQDD 246

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. UniProt/SwissProt
Match: sp|P17542|TAL1_HUMAN (T-cell acute lymphocytic leukemia protein 1 OS=Homo sapiens OX=9606 GN=TAL1 PE=1 SV=2)

HSP 1 Score: 78.1814 bits (191), Expect = 7.611e-17
Identity = 36/58 (62.07%), Postives = 45/58 (77.59%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q    
Sbjct:  193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEG 250

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. UniProt/SwissProt
Match: sp|P24899|TAL1_CHICK (T-cell acute lymphocytic leukemia protein 1 homolog OS=Gallus gallus OX=9031 GN=TAL1 PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 9.238e-17
Identity = 36/58 (62.07%), Postives = 45/58 (77.59%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q    
Sbjct:  185 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEG 242

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. UniProt/SwissProt
Match: sp|Q90YI8|TAL1_TAKRU (T-cell acute lymphocytic leukemia protein 1 OS=Takifugu rubripes OX=31033 GN=tal1 PE=2 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 1.081e-16
Identity = 37/65 (56.92%), Postives = 47/65 (72.31%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTKD 377
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L  +L  Q     ++ T D
Sbjct:  210 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYISFLSNLLEDQDGGRNVSSTTD 274

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. TrEMBL
Match: U5YTM7 (Tal protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=tal PE=2 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 3.217e-51
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 3

Query:   90 CRKPISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            CRKPISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL
Sbjct:    1 CRKPISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 82

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. TrEMBL
Match: A0A2R5LGA1 (Putative basic helix-loop-helix neural transcription factor tap-like protein (Fragment) OS=Ornithodoros turicata OX=34597 PE=4 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 4.818e-20
Identity = 45/87 (51.72%), Postives = 60/87 (68.97%), Query Frame = 3

Query:   84 SNCRKPISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQ 344
            ++C +P+S    T      S  + +  A R   NSRER RQQ+VN AF+DLR+++P HPPDKKLSK+EILR AI+YIR+L  IL +Q
Sbjct:    2 TSCDEPLSADDNTAWTPQRSAPVPRRAARRVFTNSRERWRQQNVNGAFSDLRRLVPTHPPDKKLSKNEILRLAIRYIRLLSSILEYQ 88

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. TrEMBL
Match: A0A4Z2DJL5 (T-cell acute lymphocytic leukemia protein 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_000217 PE=4 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 7.229e-19
Identity = 46/81 (56.79%), Postives = 57/81 (70.37%), Query Frame = 3

Query:  153 SKSVAPRKSY-NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTKDIYCIN 392
            S S  P  S  +SRER+RQ+SVN AF  LR ILP HPPDKKLSKHEILR +IKYI ILE IL +Q   +E+  +  + C++
Sbjct:    3 SSSTKPDTSLLDSRERQRQRSVNQAFAALRCILPTHPPDKKLSKHEILRLSIKYIHILESILKYQ---DEVEESSLVSCVS 80

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. TrEMBL
Match: K1PYP0 (T-cell acute lymphocytic leukemia protein 1 OS=Crassostrea gigas OX=29159 GN=CGI_10003531 PE=4 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 1.735e-18
Identity = 41/64 (64.06%), Postives = 51/64 (79.69%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTK 374
            NSRER RQQ+VN AF DLR+++P HPPDKKLSKHEILR  I+YIR+LE +L +QS H ++   K
Sbjct:  132 NSRERWRQQNVNGAFADLRKLVPTHPPDKKLSKHEILRCTIRYIRLLENVLEYQS-HGDVKRVK 194

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. TrEMBL
Match: Q962A3 (Transcription factor Tal OS=Crassostrea gigas OX=29159 PE=2 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 1.735e-18
Identity = 41/64 (64.06%), Postives = 51/64 (79.69%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTK 374
            NSRER RQQ+VN AF DLR+++P HPPDKKLSKHEILR  I+YIR+LE +L +QS H ++   K
Sbjct:  132 NSRERWRQQNVNGAFADLRKLVPTHPPDKKLSKHEILRCTIRYIRLLENVLEYQS-HGDVKRVK 194

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Cavefish
Match: ENSAMXT00000044683.1 (protein lyl-1-like [Source:NCBI gene;Acc:103047713])

HSP 1 Score: 79.337 bits (194), Expect = 6.207e-18
Identity = 40/73 (54.79%), Postives = 55/73 (75.34%), Query Frame = 3

Query:  132 LNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSN 350
            L L+    + +A R   NSRER RQQ+VN AF++LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q++
Sbjct:  229 LELTECPPQKIARRVFTNSRERWRQQNVNGAFSELRKLIPTHPPDKKLSKNEILRLAMKYINFLVKLLNDQAS 301

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BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Cavefish
Match: tal1 (T-cell acute lymphocytic leukemia 1 [Source:NCBI gene;Acc:30766])

HSP 1 Score: 78.1814 bits (191), Expect = 1.327e-17
Identity = 38/65 (58.46%), Postives = 50/65 (76.92%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTKD 377
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L ++LN Q   +E+ +  D
Sbjct:  243 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQ---DEVMVGSD 304

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Cavefish
Match: tal2 (TAL bHLH transcription factor 2 [Source:NCBI gene;Acc:103042451])

HSP 1 Score: 70.4774 bits (171), Expect = 1.899e-16
Identity = 32/58 (55.17%), Postives = 43/58 (74.14%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHN 356
            N+RER RQ +VNTAF +LR+++P HPP+KKLSK+EILR A++YI  L  +L  Q    
Sbjct:    8 NTRERWRQHNVNTAFAELRKLIPTHPPEKKLSKNEILRLAMRYITFLVTLLEKQQGEG 65

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Cavefish
Match: ENSAMXT00000026732.2 (helix-loop-helix protein 2-like [Source:NCBI gene;Acc:103035065])

HSP 1 Score: 61.6178 bits (148), Expect = 8.061e-13
Identity = 30/57 (52.63%), Postives = 40/57 (70.18%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNF 341
            R ++ +RER R ++ N AF +LR++LP  PPDKKLSK EILR AI YI  L  +L+ 
Sbjct:   66 RSAHATRERIRVEAFNVAFGELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 122

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Cavefish
Match: nhlh2 (helix-loop-helix protein 2-like [Source:NCBI gene;Acc:103037174])

HSP 1 Score: 59.6918 bits (143), Expect = 4.260e-12
Identity = 30/56 (53.57%), Postives = 40/56 (71.43%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILN 338
            R ++ +RER R ++ N AF +LR++LP  PPDKKLSK EILR AI YI  L  +L+
Sbjct:   66 RLAHATRERIRVEAFNVAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 121

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002470.1 (pep scaffold:Pmarinus_7.0:GL487131:18401:21594:-1 gene:ENSPMAG00000002259.1 transcript:ENSPMAT00000002470.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.2478 bits (173), Expect = 1.824e-17
Identity = 34/54 (62.96%), Postives = 44/54 (81.48%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQ 344
            NSRER RQQ+VN AF++LR++LP HPPD+KLSK+EILR A++YI  L  +L  Q
Sbjct:   28 NSRERWRQQNVNGAFSELRRLLPTHPPDRKLSKNEILRLAMRYIDFLVALLRDQ 81

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Sea Lamprey
Match: scxa (scleraxis bHLH transcription factor a [Source:ZFIN;Acc:ZDB-GENE-060503-414])

HSP 1 Score: 55.4546 bits (132), Expect = 6.096e-11
Identity = 28/55 (50.91%), Postives = 36/55 (65.45%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R++ N+RER+R QSVN+AF  LR ++P  P D+KLSK E L  A  YI  L   L
Sbjct:   38 RRAANARERDRTQSVNSAFTALRTLIPTEPADRKLSKLETLLLASSYIAHLGNTL 92

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004072.1 (pep scaffold:Pmarinus_7.0:GL492732:1750:4325:-1 gene:ENSPMAG00000003727.1 transcript:ENSPMAT00000004072.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.0694 bits (131), Expect = 3.131e-10
Identity = 27/56 (48.21%), Postives = 37/56 (66.07%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILN 338
            R++ N RER R QS+N AF  LR  +P  P +K+LSK + LR AI YI  L E+++
Sbjct:  133 RQAANQRERRRMQSINAAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYISFLGELVH 188

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Sea Lamprey
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410])

HSP 1 Score: 52.7582 bits (125), Expect = 4.291e-10
Identity = 27/55 (49.09%), Postives = 37/55 (67.27%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R + N RER R  S+N+AF +LR  +P  P +K+LSK + LR AI YI +L +IL
Sbjct:   35 RTAANVRERRRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLRDIL 89

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011442.1 (pep scaffold:Pmarinus_7.0:GL478554:30221:30385:-1 gene:ENSPMAG00000010415.1 transcript:ENSPMAT00000011442.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 8.677e-10
Identity = 26/50 (52.00%), Postives = 35/50 (70.00%), Query Frame = 3

Query:  189 RERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILN 338
            RER+R QS+N AF+ LRQI+P  P D KLSK + L+ A +YI  L ++L 
Sbjct:    1 RERQRTQSLNEAFSSLRQIIPTLPSD-KLSKIQTLKLATRYIDFLYQVLQ 49

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Nematostella
Match: EDO46193 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQN3])

HSP 1 Score: 70.8626 bits (172), Expect = 1.347e-17
Identity = 33/52 (63.46%), Postives = 44/52 (84.62%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILN 338
            NSRER RQQ VN AF +LR+++P +PP++KLSK+EILR A+KYI+ LE IL+
Sbjct:    7 NSRERWRQQHVNLAFAELRKLIPTYPPERKLSKNEILRFAMKYIKFLENILS 58

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Nematostella
Match: EDO46194 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQN4])

HSP 1 Score: 75.8702 bits (185), Expect = 2.158e-17
Identity = 35/64 (54.69%), Postives = 46/64 (71.88%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEI 362
            R   N +ER RQQSVN AF ++R++LP +PPDKKLSK EILR A+KYI+ L+ +L    +  EI
Sbjct:   52 RTVTNKKERWRQQSVNLAFAEIRKLLPTYPPDKKLSKVEILRTAVKYIQFLDGVLEGMGDGEEI 115

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Nematostella
Match: EDO46140 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQN5])

HSP 1 Score: 71.633 bits (174), Expect = 1.243e-16
Identity = 33/51 (64.71%), Postives = 41/51 (80.39%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            NSRER RQ  VN AF +LR++LP +PPDKKLSKHEILR  +KYI+ L+ +L
Sbjct:   72 NSRERWRQYQVNLAFAELRKLLPTYPPDKKLSKHEILRSTMKYIKFLDGLL 122

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Nematostella
Match: EDO42924 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZZ0])

HSP 1 Score: 58.151 bits (139), Expect = 1.210e-12
Identity = 30/55 (54.55%), Postives = 36/55 (65.45%), Query Frame = 3

Query:  171 RKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            R++ N+RER R  SVN AFN LR ++P  P D+KLSK E LR A  YI  L  IL
Sbjct:    3 RQAANARERNRTHSVNAAFNALRLLIPTEPSDRKLSKIETLRLASSYIAHLSTIL 57

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Nematostella
Match: EDO48977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI67])

HSP 1 Score: 55.8398 bits (133), Expect = 1.290e-11
Identity = 26/59 (44.07%), Postives = 37/59 (62.71%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNE 359
            N+RERER + +N AF  LR  LPC+  D  ++K   LR AI YI+ L ++L  +S+  E
Sbjct:    8 NARERERMRVLNNAFQSLRDALPCYIADGHMAKITTLRLAINYIKALTDVLRDESSTGE 66

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Medaka
Match: ENSORLT00000004704.2 (T-cell acute lymphocytic leukemia protein 1 homolog [Source:NCBI gene;Acc:101175459])

HSP 1 Score: 80.8777 bits (198), Expect = 1.945e-18
Identity = 38/65 (58.46%), Postives = 50/65 (76.92%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTKD 377
            NSRER RQQ+VN AF++LR+++P HPPDKKLSK+EILR A+KYI  L  +LN Q+     N T++
Sbjct:  298 NSRERWRQQNVNGAFSELRKLIPTHPPDKKLSKNEILRLAVKYIDFLVTLLNDQAQGKSGNSTEE 362

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Medaka
Match: ENSORLT00000017495.2 (pep primary_assembly:ASM223467v1:4:24388791:24389132:-1 gene:ENSORLG00000013953.2 transcript:ENSORLT00000017495.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 4.474e-18
Identity = 34/55 (61.82%), Postives = 47/55 (85.45%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQS 347
            NSRER RQQ+VN AF +LR+++P HPPD+KLSK+EILR A++YIR L+++L+ Q 
Sbjct:    8 NSRERWRQQNVNGAFAELRRLIPTHPPDRKLSKNEILRLALRYIRFLDQLLSEQD 62

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Medaka
Match: tal1 (T-cell acute lymphocytic leukemia protein 1 [Source:NCBI gene;Acc:101174459])

HSP 1 Score: 76.6406 bits (187), Expect = 4.138e-17
Identity = 36/63 (57.14%), Postives = 45/63 (71.43%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLT 371
            NSRER RQQ+VN AF +LR+++P HPPDKKLSK+EILR A+KYI  L  +L  Q     +  T
Sbjct:  231 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYISFLSNLLEDQDGGRNVGST 293

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Medaka
Match: tal2 (TAL bHLH transcription factor 2 [Source:NCBI gene;Acc:101160485])

HSP 1 Score: 70.8626 bits (172), Expect = 1.226e-16
Identity = 32/57 (56.14%), Postives = 43/57 (75.44%), Query Frame = 3

Query:  183 NSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNH 353
            N+RER RQ +VNTAF +LR+++P HPP+KKLSK+EILR A++YI  L  +L  Q   
Sbjct:    8 NTRERWRQHNVNTAFAELRKLIPTHPPEKKLSKNEILRLAMRYINFLVRLLESQGGQ 64

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Medaka
Match: tcf15 (transcription factor 15 [Source:NCBI gene;Acc:101172734])

HSP 1 Score: 58.9214 bits (141), Expect = 2.163e-11
Identity = 30/58 (51.72%), Postives = 37/58 (63.79%), Query Frame = 3

Query:  162 VAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            +  R + N+RER R QSVNTAF  LR ++P  P D+KLSK E LR A  YI  L  +L
Sbjct:   61 IKQRSAANARERGRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVL 118

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Planmine SMEST
Match: SMESG000067729.1 (SMESG000067729.1)

HSP 1 Score: 258.07 bits (658), Expect = 4.763e-83
Identity = 125/126 (99.21%), Postives = 125/126 (99.21%), Query Frame = 3

Query:   15 MSLCDFHQNTIKSLATEIRSNYASNCRKPISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTKDIYCIN 392
            MSLCDFHQNTIKSLATEIRSNYA NCRKPISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTKDIYCIN
Sbjct:    1 MSLCDFHQNTIKSLATEIRSNYAPNCRKPISTKSTTLHPLNLSFTLSKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNHNEINLTKDIYCIN 126

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Planmine SMEST
Match: SMESG000045286.1 (SMESG000045286.1)

HSP 1 Score: 59.6918 bits (143), Expect = 2.572e-11
Identity = 34/88 (38.64%), Postives = 50/88 (56.82%), Query Frame = 3

Query:  105 STKSTTLHPLNLSFTLSK-----SVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQSNH 353
            ST   T +  + +FT          APR   N RER R  S+NTAF +LR  +P  P +++LSK + LR AI YI +L++++ +  NH
Sbjct:   25 STSENTWNISDYTFTYQNPSTMFDEAPRYVANVRERNRIMSINTAFAELRSRVPTFPYERRLSKIDTLRLAIAYISLLQDLVWYFQNH 112

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Planmine SMEST
Match: SMESG000000956.1 (SMESG000000956.1)

HSP 1 Score: 55.8398 bits (133), Expect = 4.826e-10
Identity = 28/60 (46.67%), Postives = 40/60 (66.67%), Query Frame = 3

Query:  156 KSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEIL 335
            + +A R++ N RER R QS+N AF  LR  +P  P +K+LSK + LR AI YI  L+E++
Sbjct:   99 RKLAERQAANIRERRRMQSINEAFEGLRCHIPTMPYEKRLSKVDTLRLAISYIGFLQELI 158

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Planmine SMEST
Match: SMESG000079648.1 (SMESG000079648.1)

HSP 1 Score: 55.4546 bits (132), Expect = 6.565e-10
Identity = 29/64 (45.31%), Postives = 41/64 (64.06%), Query Frame = 3

Query:  156 KSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILNFQS 347
            K V  R++ N RER R QS+N AF  LR  +P  P +K+LSK + LR AI YI  L++++  +S
Sbjct:   99 KLVFQRQAANLRERRRMQSINEAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYINFLQDLVKTES 162

[Close]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Planmine SMEST
Match: SMESG000062901.1 (SMESG000062901.1)

HSP 1 Score: 52.7582 bits (125), Expect = 1.272e-9
Identity = 29/62 (46.77%), Postives = 41/62 (66.13%), Query Frame = 3

Query:  153 SKSVAPRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYIRILEEILN 338
            +KS A R + N RER+R  ++N AF +LR  +P    +K+LS+ E LR AI YI+ +E ILN
Sbjct:   48 NKSTAHRTAANIRERKRMINLNAAFENLRLKVPTFVFEKRLSRIETLRLAIAYIKFMECILN 109

The following BLAST results are available for this feature:

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Human
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Celegans
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Fly
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Zebrafish
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Xenopus
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Mouse
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. UniProt/SwissProt
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. TrEMBL
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Cavefish
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Sea Lamprey
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Yeast
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Nematostella
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Medaka
BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Planmine SMEST

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TAL1	1.585e-17	62.07	TAL bHLH transcription factor 1, erythroid differe...	[more]
TAL1	1.585e-17	62.07	TAL bHLH transcription factor 1, erythroid differe...	[more]
TAL2	1.060e-16	60.00	TAL bHLH transcription factor 2 [Source:HGNC Symbo...	[more]
LYL1	2.684e-16	57.81	LYL1 basic helix-loop-helix family member [Source:...	[more]
NHLH1	7.108e-12	53.57	nescient helix-loop-helix 1 [Source:HGNC Symbol;Ac...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hlh-15	3.040e-10	50.91	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q18...	[more]
lin-32	2.340e-9	46.03	pep chromosome:WBcel235:X:2229208:2230122:-1 gene:...	[more]
hlh-13	1.681e-8	43.64	Helix-loop-helix protein 13 [Source:UniProtKB/Swi...	[more]
hlh-19	3.594e-7	46.88	Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q20...	[more]
hlh-6	4.541e-6	34.18	Helix-loop-helix protein 6 [Source:UniProtKB/Swis...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HLH3B	4.201e-18	64.81	gene:FBgn0011276 transcript:FBtr0070506	[more]
ato	4.648e-11	50.91	gene:FBgn0010433 transcript:FBtr0081828	[more]
HLH4C	5.654e-11	50.91	gene:FBgn0011277 transcript:FBtr0331163	[more]
HLH4C	6.058e-11	50.91	gene:FBgn0011277 transcript:FBtr0070691	[more]
Fer1	1.922e-10	44.78	gene:FBgn0037475 transcript:FBtr0081567	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CABZ01066694.1	3.226e-20	58.82	pep chromosome:GRCz11:6:168962:172992:1 gene:ENSDA...	[more]
tal1	7.771e-18	64.29	T-cell acute lymphocytic leukemia 1 [Source:NCBI g...	[more]
tal2	1.173e-16	57.14	T-cell acute lymphocytic leukemia 2 [Source:NCBI g...	[more]
nhlh2	1.458e-12	52.63	nescient helix loop helix 2 [Source:ZFIN;Acc:ZDB-G...	[more]
atoh7	3.321e-12	47.54	atonal bHLH transcription factor 7 [Source:NCBI ge...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TAL2	7.088e-17	61.11	TAL bHLH transcription factor 2 [Source:HGNC Symbo...	[more]
tal1	1.375e-16	60.34	T-cell acute lymphocytic leukemia 1 [Source:NCBI g...	[more]
sowahc	7.645e-16	60.66	sosondowah ankyrin repeat domain family member C [...	[more]
sowahc	7.992e-16	58.73	sosondowah ankyrin repeat domain family member C [...	[more]
sowahc	8.264e-16	58.73	sosondowah ankyrin repeat domain family member C [...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tal2	7.129e-18	61.40	T cell acute lymphocytic leukemia 2 [Source:MGI Sy...	[more]
Tal1	1.590e-17	62.07	T cell acute lymphocytic leukemia 1 [Source:MGI Sy...	[more]
Tal1	1.590e-17	62.07	T cell acute lymphocytic leukemia 1 [Source:MGI Sy...	[more]
Tal1	1.590e-17	62.07	T cell acute lymphocytic leukemia 1 [Source:MGI Sy...	[more]
Lyl1	7.275e-17	57.81	lymphoblastomic leukemia 1 [Source:MGI Symbol;Acc:...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q62282\|TAL2_MOUSE	4.987e-17	61.40	T-cell acute lymphocytic leukemia protein 2 homolo...	[more]
sp\|O93507\|TAL1_DANRE	5.866e-17	64.29	T-cell acute lymphocytic leukemia protein 1 homolo...	[more]
sp\|P17542\|TAL1_HUMAN	7.611e-17	62.07	T-cell acute lymphocytic leukemia protein 1 OS=Hom...	[more]
sp\|P24899\|TAL1_CHICK	9.238e-17	62.07	T-cell acute lymphocytic leukemia protein 1 homolo...	[more]
sp\|Q90YI8\|TAL1_TAKRU	1.081e-16	56.92	T-cell acute lymphocytic leukemia protein 1 OS=Tak...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
U5YTM7	3.217e-51	100.00	Tal protein (Fragment) OS=Schmidtea mediterranea O...	[more]
A0A2R5LGA1	4.818e-20	51.72	Putative basic helix-loop-helix neural transcripti...	[more]
A0A4Z2DJL5	7.229e-19	56.79	T-cell acute lymphocytic leukemia protein 1 OS=Sch...	[more]
K1PYP0	1.735e-18	64.06	T-cell acute lymphocytic leukemia protein 1 OS=Cra...	[more]
Q962A3	1.735e-18	64.06	Transcription factor Tal OS=Crassostrea gigas OX=2...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000044683.1	6.207e-18	54.79	protein lyl-1-like [Source:NCBI gene;Acc:103047713...	[more]
tal1	1.327e-17	58.46	T-cell acute lymphocytic leukemia 1 [Source:NCBI g...	[more]
tal2	1.899e-16	55.17	TAL bHLH transcription factor 2 [Source:NCBI gene;...	[more]
ENSAMXT00000026732.2	8.061e-13	52.63	helix-loop-helix protein 2-like [Source:NCBI gene;...	[more]
nhlh2	4.260e-12	53.57	helix-loop-helix protein 2-like [Source:NCBI gene;...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000002470.1	1.824e-17	62.96	pep scaffold:Pmarinus_7.0:GL487131:18401:21594:-1 ...	[more]
scxa	6.096e-11	50.91	scleraxis bHLH transcription factor a [Source:ZFIN...	[more]
ENSPMAT00000004072.1	3.131e-10	48.21	pep scaffold:Pmarinus_7.0:GL492732:1750:4325:-1 ge...	[more]
si:dkey-34f9.3	4.291e-10	49.09	si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-41...	[more]
ENSPMAT00000011442.1	8.677e-10	52.00	pep scaffold:Pmarinus_7.0:GL478554:30221:30385:-1 ...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46193	1.347e-17	63.46	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46194	2.158e-17	54.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46140	1.243e-16	64.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42924	1.210e-12	54.55	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48977	1.290e-11	44.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000004704.2	1.945e-18	58.46	T-cell acute lymphocytic leukemia protein 1 homolo...	[more]
ENSORLT00000017495.2	4.474e-18	61.82	pep primary_assembly:ASM223467v1:4:24388791:243891...	[more]
tal1	4.138e-17	57.14	T-cell acute lymphocytic leukemia protein 1 [Sourc...	[more]
tal2	1.226e-16	56.14	TAL bHLH transcription factor 2 [Source:NCBI gene;...	[more]
tcf15	2.163e-11	51.72	transcription factor 15 [Source:NCBI gene;Acc:1011...	[more]

BLAST of T-cell acute lymphocytic leukemia protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000067729.1	4.763e-83	99.21	SMESG000067729.1	[more]
SMESG000045286.1	2.572e-11	38.64	SMESG000045286.1	[more]
SMESG000000956.1	4.826e-10	46.67	SMESG000000956.1	[more]
SMESG000079648.1	6.565e-10	45.31	SMESG000079648.1	[more]
SMESG000062901.1	1.272e-9	46.77	SMESG000062901.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016749 ID=SMED30016749|Name=T-cell acute lymphocytic leukemia protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=408bp
ATTGAATTATTTTTATGTCACTGTGTGATTTTCATCAAAATACTATCAAA
TCCTTGGCCACCGAAATTCGATCAAATTATGCTTCCAATTGTAGGAAACC
AATCTCAACGAAATCAACGACTCTGCATCCATTAAACCTGTCATTTACTC
TATCGAAATCTGTAGCACCGAGGAAATCGTACAATTCAAGAGAAAGAGAA
CGACAACAAAGCGTTAATACAGCCTTCAATGACCTCCGACAAATATTGCC
GTGTCACCCCCCGGACAAGAAATTGAGCAAACACGAAATCCTTCGTCAAG
CCATTAAGTACATTAGGATTCTGGAAGAAATCTTGAATTTTCAAAGTAAT
CACAATGAAATAAATTTGACCAAAGATATTTATTGTATTAATGTTAATAT
TTAAATTA

protein sequence of SMED30016749-orf-1

>SMED30016749-orf-1 ID=SMED30016749-orf-1|Name=SMED30016749-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=130bp
MSLCDFHQNTIKSLATEIRSNYASNCRKPISTKSTTLHPLNLSFTLSKSV
APRKSYNSRERERQQSVNTAFNDLRQILPCHPPDKKLSKHEILRQAIKYI
RILEEILNFQSNHNEINLTKDIYCINVNI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR036638	HLH_DNA-bd_sf
IPR040238	TAL-like
IPR011598	bHLH_dom

Vocabulary: **molecular function**
Term	Definition
GO:0046983	protein dimerization activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	SMART	SM00353	finulus	coord: 57..109 e-value: 5.7E-17 score: 72.4
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	PFAM	PF00010	HLH	coord: 53..103 e-value: 3.5E-17 score: 62.1
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	PROSITE	PS50888	BHLH	coord: 51..103 score: 16.406
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain	CDD	cd00083	HLH	coord: 53..107 e-value: 4.90391E-15 score: 62.6167
IPR036638	Helix-loop-helix DNA-binding domain superfamily	GENE3D	G3DSA:4.10.280.10		coord: 48..115 e-value: 4.0E-23 score: 82.7
IPR036638	Helix-loop-helix DNA-binding domain superfamily	SUPERFAMILY	SSF47459	HLH, helix-loop-helix DNA-binding domain	coord: 51..115
None	No IPR available	PANTHER	PTHR13864:SF15	HELIX LOOP HELIX PROTEIN 3B	coord: 41..109
IPR040238	T-cell acute lymphocytic leukemia protein-like	PANTHER	PTHR13864	T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED	coord: 41..109

Main menu

T-cell acute lymphocytic leukemia protein 1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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