Transmembrane protein 47

Overview
NameTransmembrane protein 47
Smed IDSMED30016730
Length (bp)2902
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transmembrane protein 47 (SMED30016730) t-SNE clustered cells

Violin plots show distribution of expression levels for Transmembrane protein 47 (SMED30016730) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transmembrane protein 47 (SMED30016730) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transmembrane protein 47 (SMED30016730) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016730

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30016730h1SMcG0018466 dd_Smed_v4_7982_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30016730h1SMcG0018466 dd_Smed_v4_12504_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30016730h1SMcG0018466 dd_Smed_v4_12504_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30016730h1SMcG0018466 dd_Smed_v6_7982_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transmembrane protein 47 vs. TrEMBL
Match: A0A4Z2DPE9 (Transmembrane 47 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_010317 PE=4 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 2.308e-19
Identity = 62/147 (42.18%), Postives = 88/147 (59.86%), Query Frame = 2 
Query: 1598 LTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVE 2038
            LT +Q   L +Y +HD+FVR RSW+ C ++L V + +F   S +W + GDS +P   GLW  C+P N TC       +       SI+CL+  + +F I G GL+ TG+C +AL  +LYYYHSAGE F VS + +  A+ LY I+ E
Sbjct:  116 LTPQQWQLLTDYHEHDLFVRTRSWSFCMAVLGVGVALFGIGSPAWKWIGDSRNPYELGLWTLCLPNNSTCLSIIYHLQNNWKLHISIICLLGCACLFGILGLGLAITGVCKSALILRLYYYHSAGECFLVSSIAIIAALILYPISAE 262
[Close]
BLAST of Transmembrane protein 47 vs. TrEMBL
Match: A0A3Q0KNT2 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 8.204e-19
Identity = 61/147 (41.50%), Postives = 87/147 (59.18%), Query Frame = 2 
Query: 1598 LTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVE 2038
            LT +Q   L +Y +HD+FVR RSW+ C ++L V + +F   S +W + GDS +P   GLW  C+P N TC       +       SI+CL+  + +F + G GL+ TG+C +AL  +LYYYHSAGE F VS +    A+ LY I+ E
Sbjct:  132 LTPQQWQLLNDYHEHDLFVRTRSWSFCMAVLGVGVTLFGIGSPAWKWIGDSRNPYELGLWTLCLPNNSTCLSIIYHLQNNWKLHISIICLLGCACLFGMLGLGLAITGVCKSALILRLYYYHSAGECFLVSSIATITALILYPISAE 278
[Close]
BLAST of Transmembrane protein 47 vs. TrEMBL
Match: A0A4Z2DPD3 (Transmembrane 47 isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_010317 PE=4 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 3.468e-17
Identity = 57/135 (42.22%), Postives = 81/135 (60.00%), Query Frame = 2 
Query: 1598 LTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTM 2002
            LT +Q   L +Y +HD+FVR RSW+ C ++L V + +F   S +W + GDS +P   GLW  C+P N TC       +       SI+CL+  + +F I G GL+ TG+C +AL  +LYYYHSAGE F VS + +
Sbjct:  116 LTPQQWQLLTDYHEHDLFVRTRSWSFCMAVLGVGVALFGIGSPAWKWIGDSRNPYELGLWTLCLPNNSTCLSIIYHLQNNWKLHISIICLLGCACLFGILGLGLAITGVCKSALILRLYYYHSAGECFLVSNLLI 250
[Close]
BLAST of Transmembrane protein 47 vs. TrEMBL
Match: G4VSK0 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 GN=Smp_143810 PE=4 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 3.168e-16
Identity = 60/147 (40.82%), Postives = 83/147 (56.46%), Query Frame = 2 
Query: 1598 LTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVE 2038
            LT +Q   L +Y +HD+FVR RSW+ C ++L V + +F   S +W + GDS +P   GLW  C+P N TC         +N +  S  CL  +       G GL+ TG+C +AL  +LYYYHSAGE F VS +    A+ LY I+ E
Sbjct:   68 LTPQQWQLLNDYHEHDLFVRTRSWSFCMAVLGVGVTLFGIGSPAWKWIGDSRNPYELGLWTLCLPNNSTCLSI--IYHLQNNW--SCACLFGM------LGLGLAITGVCKSALILRLYYYHSAGECFLVSSIATITALILYPISAE 204
[Close]
BLAST of Transmembrane protein 47 vs. TrEMBL
Match: H2KS83 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CLF_108460 PE=4 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 1.161e-14
Identity = 53/146 (36.30%), Postives = 77/146 (52.74%), Query Frame = 2 
Query: 1598 LTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITV 2035
            LT +Q   L +Y +HD+F+R RSW  C ++  V + +F   S +W + GD   P   GLW  C P N +C       +       S++C +    +F   G GL+ TG C +AL  ++YYYHSAGE F VSG+    ++ LY  T 
Sbjct:   82 LTPQQWQLLTDYHEHDLFIRTRSWGFCLAIFGVGVAVFGMGSPAWKWIGDIKKPYEMGLWAMCYP-NSSCIPLVYHLKDDWKMHTSVICFLGCGCLFGFLGIGLAVTGACRSALIIRMYYYHSAGECFLVSGIATGGSLILYPFTA 226
[Close]
BLAST of Transmembrane protein 47 vs. Planmine SMEST
Match: SMESG000061681.1 (SMESG000061681.1)

HSP 1 Score: 540.036 bits (1390), Expect = 1.097e-179
Identity = 313/334 (93.71%), Postives = 315/334 (94.31%), Query Frame = 3 
Query:  639 MLIFLSTSFIVILNTESSFYSHLMKPHIYISYSNNPDEYVTHSNLYGYYHTKSPLPTHQTIMSKQAPDXXXXXXXXXXXXPKLQNSEIKPNKMPNKTHYLHTLSVEDAQQEKRNRILRQKXXXXXXXXXXXXDYTSADDLXXXXXXXXXXXXXXXXXXLETKVIYSRKTSPVPVSNRKVSWRTLPNQSISTNPMTRGFSRSENFTLETIESSGSSHANNDHSTPQSLTENDQNIRVAKQFTKYRNADLFQENFSNIYHNYSDWIFKQNNTKQRTYYNSEYDFGTMIYNSDETDESNCPLDHCHQNSE----RNGKKNVVMKKTD*LMSKFIIWS 1628
            MLIFLSTSFIVILNTESSFYSHLMKPHIYISYSNNPDEYVTHSNLYGYYHTKSPLPTHQTIMSKQAPDSSSIVTYTTYSSPKLQNSEIKPNKMPNKTHYLHTLSVEDAQQEKRNRILRQKSSTETSGLGSSLDYTSADDLNNRSASNSRRHSSTSNTALETKVIYSRKTSPVPVSNRKVSWRTLPNQSISTNPMTRGFSRSENFTLETIESSGSSHANNDHSTPQSLTENDQNIRVAKQFTKYRNADLFQENFSNIYHNYSDWIFKQNNTKQRTYYNSEYDFGTMIYNSDETDESNCPLDHCHQNS+    RN   N      D    K+  WS
Sbjct:    1 MLIFLSTSFIVILNTESSFYSHLMKPHIYISYSNNPDEYVTHSNLYGYYHTKSPLPTHQTIMSKQAPDSSSIVTYTTYSSPKLQNSEIKPNKMPNKTHYLHTLSVEDAQQEKRNRILRQKSSTETSGLGSSLDYTSADDLNNRSASNSRRHSSTSNTALETKVIYSRKTSPVPVSNRKVSWRTLPNQSISTNPMTRGFSRSENFTLETIESSGSSHANNDHSTPQSLTENDQNIRVAKQFTKYRNADLFQENFSNIYHNYSDWIFKQNNTKQRTYYNSEYDFGTMIYNSDETDESNCPLDHCHQNSDTQVIRNSFNNSKTCSFDSSKVKWCNWS 334

HSP 2 Score: 484.952 bits (1247), Expect = 1.690e-158
Identity = 285/285 (100.00%), Postives = 285/285 (100.00%), Query Frame = 2 
Query: 1592 NRLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHFKFHKHRYGYTFXXXXXXXXXXXXXXXXXXMDELIQGSTKLRGYSCLAKCFRCWCCCKRSHAPEARPHIYHEXXXXXXXXXXXXXXXXXXXPISGQQTTNSVGTSSQLTNNNGHKSHEPATQWMTENDIEEDFV 2446
            NRLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVSSIFSIGGSGLSFTGLCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHFKFHKHRYGYTFWLAWLSAALLLLSALNLLMDELIQGSTKLRGYSCLAKCFRCWCCCKRSHAPEARPHIYHESNQSHSIRRNHSRISQHRRPISGQQTTNSVGTSSQLTNNNGHKSHEPATQWMTENDIEEDFV
Sbjct:  465 NRLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVSSIFSIGGSGLSFTGLCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHFKFHKHRYGYTFWLAWLSAALLLLSALNLLMDELIQGSTKLRGYSCLAKCFRCWCCCKRSHAPEARPHIYHESNQSHSIRRNHSRISQHRRPISGQQTTNSVGTSSQLTNNNGHKSHEPATQWMTENDIEEDFV 749
[Close]
BLAST of Transmembrane protein 47 vs. Planmine SMEST
Match: SMESG000061681.1 (SMESG000061681.1)

HSP 1 Score: 495.738 bits (1275), Expect = 7.127e-163
Identity = 290/311 (93.25%), Postives = 292/311 (93.89%), Query Frame = 3 
Query:  708 MKPHIYISYSNNPDEYVTHSNLYGYYHTKSPLPTHQTIMSKQAPDXXXXXXXXXXXXPKLQNSEIKPNKMPNKTHYLHTLSVEDAQQEKRNRILRQKXXXXXXXXXXXXDYTSADDLXXXXXXXXXXXXXXXXXXLETKVIYSRKTSPVPVSNRKVSWRTLPNQSISTNPMTRGFSRSENFTLETIESSGSSHANNDHSTPQSLTENDQNIRVAKQFTKYRNADLFQENFSNIYHNYSDWIFKQNNTKQRTYYNSEYDFGTMIYNSDETDESNCPLDHCHQNSE----RNGKKNVVMKKTD*LMSKFIIWS 1628
            MKPHIYISYSNNPDEYVTHSNLYGYYHTKSPLPTHQTIMSKQAPDSSSIVTYTTYSSPKLQNSEIKPNKMPNKTHYLHTLSVEDAQQEKRNRILRQKSSTETSGLGSSLDYTSADDLNNRSASNSRRHSSTSNTALETKVIYSRKTSPVPVSNRKVSWRTLPNQSISTNPMTRGFSRSENFTLETIESSGSSHANNDHSTPQSLTENDQNIRVAKQFTKYRNADLFQENFSNIYHNYSDWIFKQNNTKQRTYYNSEYDFGTMIYNSDETDESNCPLDHCHQNS+    RN   N      D    K+  WS
Sbjct:    1 MKPHIYISYSNNPDEYVTHSNLYGYYHTKSPLPTHQTIMSKQAPDSSSIVTYTTYSSPKLQNSEIKPNKMPNKTHYLHTLSVEDAQQEKRNRILRQKSSTETSGLGSSLDYTSADDLNNRSASNSRRHSSTSNTALETKVIYSRKTSPVPVSNRKVSWRTLPNQSISTNPMTRGFSRSENFTLETIESSGSSHANNDHSTPQSLTENDQNIRVAKQFTKYRNADLFQENFSNIYHNYSDWIFKQNNTKQRTYYNSEYDFGTMIYNSDETDESNCPLDHCHQNSDTQVIRNSFNNSKTCSFDSSKVKWCNWS 311

HSP 2 Score: 485.337 bits (1248), Expect = 7.617e-159
Identity = 285/285 (100.00%), Postives = 285/285 (100.00%), Query Frame = 2 
Query: 1592 NRLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHFKFHKHRYGYTFXXXXXXXXXXXXXXXXXXMDELIQGSTKLRGYSCLAKCFRCWCCCKRSHAPEARPHIYHEXXXXXXXXXXXXXXXXXXXPISGQQTTNSVGTSSQLTNNNGHKSHEPATQWMTENDIEEDFV 2446
            NRLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVSSIFSIGGSGLSFTGLCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHFKFHKHRYGYTFWLAWLSAALLLLSALNLLMDELIQGSTKLRGYSCLAKCFRCWCCCKRSHAPEARPHIYHESNQSHSIRRNHSRISQHRRPISGQQTTNSVGTSSQLTNNNGHKSHEPATQWMTENDIEEDFV
Sbjct:  442 NRLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVSSIFSIGGSGLSFTGLCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHFKFHKHRYGYTFWLAWLSAALLLLSALNLLMDELIQGSTKLRGYSCLAKCFRCWCCCKRSHAPEARPHIYHESNQSHSIRRNHSRISQHRRPISGQQTTNSVGTSSQLTNNNGHKSHEPATQWMTENDIEEDFV 726
[Close]
BLAST of Transmembrane protein 47 vs. Planmine SMEST
Match: SMESG000029557.1 (SMESG000029557.1)

HSP 1 Score: 104.76 bits (260), Expect = 1.489e-23
Identity = 66/187 (35.29%), Postives = 106/187 (56.68%), Query Frame = 2 
Query: 1595 RLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHF-KFHKHRYGYTFXXXXXXXXXXXXXXXXXXMDELIQ 2152
            +LT+ +I  L EYWDH  F++ R W LC  LL++ LQ+F   S +W ++G+   PN+SGLW  C  RN TC+ A         +  S++ L  + S+ ++  +   F+G+ V  L +KLYYYHS  E F V+ ++    + ++++  +  F KF   RYGY + L W+   L + + + L +DE IQ
Sbjct:  170 KLTYSEIQLLTEYWDHKNFIKSRKWGLCTGLLSLGLQLFSVCSSTWIYYGEKEIPNHSGLWLKCNMRNRTCSLAI----QTPNWLKSVIFLSIIGSLCNLLATFFGFSGVFVKHLPKKLYYYHSGSEFFCVASLSYGSGLLIFTLFSKNQFNKFTWFRYGYAYTLGWIGVLLSMTAFILLKLDEFIQ 352
[Close]
BLAST of Transmembrane protein 47 vs. Planmine SMEST
Match: SMESG000055359.1 (SMESG000055359.1)

HSP 1 Score: 103.219 bits (256), Expect = 4.134e-23
Identity = 65/187 (34.76%), Postives = 106/187 (56.68%), Query Frame = 2 
Query: 1595 RLTHEQIHYLVEYWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHF-KFHKHRYGYTFXXXXXXXXXXXXXXXXXXMDELIQ 2152
            +LT+ +I  L EYWDH  F++ R W LC  LL++ LQ+F   S +W ++G+   PN+SGLW  C  RN TC+ A         +  S++ L  + S+ ++  +   F+G+ V  L +KLYYYHS  E + V+ ++    + ++++  +  F KF   RYGY + L W+   L + + + L +DE IQ
Sbjct:  170 KLTYSEIQLLTEYWDHKNFIKSRKWGLCTGLLSLGLQLFSVCSSTWIYYGEKEIPNHSGLWLKCNMRNRTCSLAI----QTPNWLKSVIFLSIIGSLCNLLATFFGFSGVFVKHLPKKLYYYHSGSEFYCVASLSYGSGLLIFTLFSKNQFNKFTWFRYGYAYTLGWIGVLLSMTAFILLKLDEFIQ 352
[Close]
BLAST of Transmembrane protein 47 vs. Planmine SMEST
Match: SMESG000074883.1 (SMESG000074883.1)

HSP 1 Score: 52.373 bits (124), Expect = 7.570e-7
Identity = 35/150 (23.33%), Postives = 75/150 (50.00%), Query Frame = 2 
Query: 1631 YWDHDIFVRLRSWALCFSLLAVALQIFVGLSGSWSFFGDSHHPNYSGLWQTCIPRNHTCTFAFPFTRAKNGYRDSILCLIAVXXXXXXXXXXXXXXXXCVTALARKLYYYHSAGEIFFVSGMTMTLAVSLYSITVEFHFKFHKHRYGYTF 2080
            + ++ +FV  R+W   F+++A+   ++V +S  W   GD +HP  +GL   C   N +C   +        +   ++  I +SS+  + G  ++  G     + +++YYYHS+GE   ++   + + + ++ I+     KF+   +G +F
Sbjct:   97 FLENQMFVMSRTWGTTFTIVALVFNVYVLISPYWFSMGDRYHPTNAGLLMICGSHNDSCIQLYSHWMDIPNWTKLLIGFICLSSLTGLCGLIVAILGCIHKPIHKQMYYYHSSGEFSVIAFAMIMVGLLIFFISDRRTLKFNS--FGLSF 244
The following BLAST results are available for this feature:
BLAST of Transmembrane protein 47 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2DPE92.308e-1942.18Transmembrane 47 isoform 1 OS=Schistosoma japonicu... [more]
A0A3Q0KNT28.204e-1941.50Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4Z2DPD33.468e-1742.22Transmembrane 47 isoform 2 OS=Schistosoma japonicu... [more]
G4VSK03.168e-1640.82Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
H2KS831.161e-1436.30Uncharacterized protein OS=Clonorchis sinensis OX=... [more]
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BLAST of Transmembrane protein 47 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transmembrane protein 47 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000061681.11.097e-17993.71SMESG000061681.1[more]
SMESG000061681.17.127e-16393.25SMESG000061681.1[more]
SMESG000029557.11.489e-2335.29SMESG000029557.1[more]
SMESG000055359.14.134e-2334.76SMESG000055359.1[more]
SMESG000074883.17.570e-723.33SMESG000074883.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016730 ID=SMED30016730|Name=Transmembrane protein 47|organism=Schmidtea mediterranea sexual|type=transcript|length=2902bp
ATATAAATCTTATATGATAATTTATCAGAAAATAAAAACTTAACATTAAT
GTTATGATTAATGAATTACACATTGAAAATAGTCTCTAACCAATTGTTTA
GTACCTTTCAAATTGAAAATGGGTAATACTGAAAATTTACGGCAGCAAAA
TATTGTAGCAGGAACTGATAAATATTGAGATAGTTCTCAATATTGAGAAA
ATTTTCACAAATACAAAAATGCTTGCATTCCCATTATCTAGAGTTTCTCC
CATTAATCCATGCTAACAGACAGTGAGACACACAGACGCATACAGTTTCA
CAGACAAACTCGATTGGTCTCTGTCAATCGACACACAAGCAATTTTCATT
TGGCGAGTAAGACAATTTTAGCATACATTGCTTGTGTCTTATTTTCTTTC
TCCCATATGAGAAAATGAAATTATTTATTCCACATCGCAATGAATGAGGA
GGAAAACATGTACTGATGTTGAAATTACTACGATATAAGCCAAATATTTG
AGAAAACCTTCAATGAATAGACACTATATCTATCAACTTCGAATTTGAAG
CAAACATTAGGTATGAATCGAGTGTTGACCAGAACTTGATCAAAAAATTA
ACCATCGATATGGGATTGTGTTATTTGTATATTCTAACATGTTGATTTTT
CTATCGACTTCTTTCATTGTCATACTGAACACCGAATCGAGTTTTTATTC
GCATTTGATGAAGCCGCATATCTATATTTCCTATTCCAATAATCCAGATG
AATATGTTACTCATTCGAATCTTTACGGTTATTATCACACAAAATCTCCG
TTGCCAACACATCAGACAATCATGTCTAAACAGGCTCCAGACAGTAGTAG
TATTGTTACTTATACGACTTATTCGTCGCCAAAACTGCAAAATAGCGAAA
TAAAACCAAATAAAATGCCAAATAAAACCCATTATTTGCACACATTGTCA
GTGGAGGACGCACAGCAAGAAAAGCGCAACCGGATTTTGCGTCAAAAAAG
CAGCACCGAAACCAGTGGATTAGGTAGCAGTCTGGATTATACATCAGCAG
ACGACCTAAACAACCGGTCAGCATCGAATTCGCGGCGTCACTCATCGACA
TCGAACACTGCACTGGAAACCAAAGTCATTTATTCACGGAAAACAAGCCC
GGTTCCAGTGAGCAATAGAAAAGTTTCCTGGCGGACATTGCCCAATCAGT
CTATTAGCACCAATCCGATGACGCGAGGGTTTTCTAGATCGGAAAACTTT
ACTCTGGAAACCATTGAAAGCAGTGGCAGCAGTCATGCAAATAACGACCA
CAGTACTCCGCAATCGCTGACAGAGAACGATCAGAACATTCGAGTCGCTA
AGCAGTTTACTAAATACAGAAATGCGGATTTATTTCAAGAAAATTTTTCA
AATATCTATCACAATTATTCGGATTGGATTTTTAAACAAAACAACACTAA
ACAAAGGACTTATTATAATTCTGAATATGATTTCGGTACTATGATTTATA
ATAGCGATGAAACGGACGAGTCAAACTGTCCACTCGATCATTGTCATCAA
AATTCAGAAAGAAATGGGAAAAAAAACGTCGTGATGAAGAAAACCGATTA
ACTCATGAGCAAATTCATTATCTGGTCGAATATTGGGATCATGATATATT
TGTTCGTTTGCGATCATGGGCCCTGTGTTTTTCCTTACTGGCTGTAGCTT
TACAGATATTTGTCGGTCTCAGCGGTTCGTGGTCATTCTTTGGAGACAGT
CATCATCCAAATTATTCCGGTTTGTGGCAGACTTGCATTCCAAGAAATCA
CACCTGTACTTTCGCCTTCCCTTTCACAAGAGCGAAAAACGGATACCGAG
ACAGTATCCTTTGTTTAATTGCAGTATCTAGTATTTTCAGTATTGGTGGC
AGCGGTCTCTCATTTACCGGTCTCTGTGTCACCGCTTTAGCTAGGAAATT
GTACTATTATCACTCAGCGGGCGAGATTTTTTTCGTCTCAGGTATGACAA
TGACCTTAGCAGTATCTCTGTATTCGATAACGGTAGAATTTCATTTCAAA
TTCCATAAACATCGTTATGGCTATACTTTTTGGCTCGCATGGCTTTCTGC
TGCATTATTGCTGTTGTCTGCTCTTAATCTGCTGATGGATGAATTAATTC
AAGGCTCAACGAAATTGCGCGGTTACTCTTGTCTTGCCAAATGTTTCCGA
TGCTGGTGTTGCTGCAAGCGATCTCATGCACCGGAAGCTCGGCCTCACAT
TTATCATGAATCCAACCAATCTCACTCGATAAGACGCAACCACAGTCGAA
TCAGCCAGCACAGAAGACCAATCAGTGGACAGCAAACCACAAATAGTGTC
GGAACGTCGTCTCAATTGACCAATAACAACGGTCACAAATCTCACGAACC
AGCTACTCAATGGATGACAGAAAACGATATCGAAGAAGATTTTGTATAGT
TCTAATCAAATATTCCATATGTGATACTCAACTGACAGATTTTATTGTAA
TTGTGATGATCTATTCTGTAGCTCTACAAATAATTGATTATTTCCACTAT
TTTTTGGCACTTGTCAACTGATACAAAGTGTTTTCTATTTTTATATTTTG
AATTGAGCTGAAAAATCAGTGGGAATGTATGTGAGTGTGTGTGCGAGTGA
GTGTGTGTCAGTGTCAATAGAAGCGTGTGTGTGCGAGTGTGTGTGTGTAT
CGATGTGCGTGTTTGTACCGGTGTTTTGGATGAATTTCGGAGGATTTGTT
TTAAATTTATCTCAGTCAATTAGTTATTCAACTCAACCGTTTTTTAATAA
GGTTTTATGGATAATATTCCAGCGCAATGATTTCTGAGAATAGATATTTA
GAATTCTATTTTGATCATAGATGTTACTATTTACTAAATTGTAGTATTTC
CA
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protein sequence of SMED30016730-orf-1

>SMED30016730-orf-1 ID=SMED30016730-orf-1|Name=SMED30016730-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=321bp
MLIFLSTSFIVILNTESSFYSHLMKPHIYISYSNNPDEYVTHSNLYGYYH
TKSPLPTHQTIMSKQAPDSSSIVTYTTYSSPKLQNSEIKPNKMPNKTHYL
HTLSVEDAQQEKRNRILRQKSSTETSGLGSSLDYTSADDLNNRSASNSRR
HSSTSNTALETKVIYSRKTSPVPVSNRKVSWRTLPNQSISTNPMTRGFSR
SENFTLETIESSGSSHANNDHSTPQSLTENDQNIRVAKQFTKYRNADLFQ
ENFSNIYHNYSDWIFKQNNTKQRTYYNSEYDFGTMIYNSDETDESNCPLD
HCHQNSERNGKKNVVMKKTD*
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protein sequence of SMED30016730-orf-2

>SMED30016730-orf-2 ID=SMED30016730-orf-2|Name=SMED30016730-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=152bp
MTMTLAVSLYSITVEFHFKFHKHRYGYTFWLAWLSAALLLLSALNLLMDE
LIQGSTKLRGYSCLAKCFRCWCCCKRSHAPEARPHIYHESNQSHSIRRNH
SRISQHRRPISGQQTTNSVGTSSQLTNNNGHKSHEPATQWMTENDIEEDF
V*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR004031PMP22/EMP/MP20/Claudin