Protocadherin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30016728 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 296.204 bits (757), Expect = 2.283e-83 Identity = 241/795 (30.31%), Postives = 372/795 (46.79%), Query Frame = 3
Query: 339 DFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNLCHLVPTCCPKK--NNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI--SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT---VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARL----------RIIIESINGDSI 2633
D+G P + E + Y ++ G + T E IDR+ L C + + C L+ + D ++ IEV+DINDN+P ++ + E + IG + +A D D G NG++ Y + PE E + ++Q +L++ LDRE+ D Y+ + DGG+P S + V V D NDN+P FE+ Y ++EN VIQ+KA D+D N +IEY PE +L ++ N+G I V+ +D E +T+ V A D G + + V++ ++D+NDN+P I + A I+E+ A VA+ V D+D EN VTC + + F L + + + Y + T D E+ T IV D GNP +++ S+ V V D+ND AP F++ E+ KPG + I A+D D G NA L YS+ + A +F+I+ G++ ++T LDRE ES AAD G P TA + V V D NDN P F+ V+EN A P+ V V D D+G N++ ++++ + ++ IQ + S S DRE + Y ++A D G PP+S + INVLD ND P PS ++ + + P+T G T++Q+ A D D G N+EL YS N LF + SG I+L++ I+ H + L+V V D G P TA + R ++E++ G S+
Sbjct: 80 DYGFPDVG-HLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRE-----CQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE-----LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ--APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG--------DFVIQNGTGTILSSLS------------------FDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYG-LFQIGSHSGAITLEKEIERRHH-GLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSL 830
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 295.434 bits (755), Expect = 2.363e-82 Identity = 241/795 (30.31%), Postives = 372/795 (46.79%), Query Frame = 3
Query: 339 DFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNLCHLVPTCCPKK--NNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI--SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT---VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARL----------RIIIESINGDSI 2633
D+G P + E + Y ++ G + T E IDR+ L C + + C L+ + D ++ IEV+DINDN+P ++ + E + IG + +A D D G NG++ Y + PE E + ++Q +L++ LDRE+ D Y+ + DGG+P S + V V D NDN+P FE+ Y ++EN VIQ+KA D+D N +IEY PE +L ++ N+G I V+ +D E +T+ V A D G + + V++ ++D+NDN+P I + A I+E+ A VA+ V D+D EN VTC + + F L + + + Y + T D E+ T IV D GNP +++ S+ V V D+ND AP F++ E+ KPG + I A+D D G NA L YS+ + A +F+I+ G++ ++T LDRE ES AAD G P TA + V V D NDN P F+ V+EN A P+ V V D D+G N++ ++++ + ++ IQ + S S DRE + Y ++A D G PP+S + INVLD ND P PS ++ + + P+T G T++Q+ A D D G N+EL YS N LF + SG I+L++ I+ H + L+V V D G P TA + R ++E++ G S+
Sbjct: 80 DYGFPDVG-HLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRE-----CQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE-----LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ--APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG--------DFVIQNGTGTILSSLS------------------FDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYG-LFQIGSHSGAITLEKEIERRHH-GLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSL 830
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH10 (protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404]) HSP 1 Score: 280.026 bits (715), Expect = 7.750e-79 Identity = 214/674 (31.75%), Postives = 318/674 (47.18%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYI-INTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSF-------------------NGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFG---KDAKIF---SINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLS-TANITVIVKDINDNFP----------------FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKL-IIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLD 2285
Y ++N GV+ + +IDR+ +C P+C L L + ++ + + IEV DINDN P + + +L + SE + G L A D D GTN + Y I+P SY ++ T N+ +LVL+K LDRE+ + +++ A DGG G+ + + V D NDN P F++ VY +S+ EN T VIQL A D D NG++ Y SS P +LF + +G + V ELDYE + V+A D+G + C V++ + D NDN+PEI F T ++E APG +VA+FSV D+DS ENG+V C L + + F R+ Y I T DRE T +V D G P +TS S+ V V D+ND AP FS+ Y +V E+ PG Y++ ++ATD+DEG NA L+YSI + +F SIN +G ++ D E ++ F A D+G P+ L+ A + +++ D NDN P LP+S L L +V DAD+G N+ ++V R +E LFR ++ G+L R R+ YE+VIE D G PP S+ + + ++D
Sbjct: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCV--------LHLEVFLENPL-ELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN------SYFSLDVQTQGDGNRF-AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS----TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCEL--LGDVPF---RLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYL--------LTRVAAVDADDGENARLTYSIV---------RGNE---MNLFRMDWRT-----------GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680 HSP 2 Score: 149.058 bits (375), Expect = 8.641e-36 Identity = 164/616 (26.62%), Postives = 260/616 (42.21%), Query Frame = 3
Query: 900 KVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNS-------GYIHVRWELDYETYTTISLIVEANDMGNL-------------------RRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKV----TCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKL--FRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVL--DVNDCKPKFIFP-SGSNSTV--KVKPRTV-SGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVC-CYVLIVVVKDNGIPRLEDTARLRIIIESING 2624
+V + V D NDN P F + + ++E+ T A D D N +Y+I+ FS++ + + + LD E ++ A D G +R T + I + D NDN P F+ +T + EN PG LV + D D +NG+V + H+ P A E F L P T ++S D E+ ++ D G V V V D ND AP S + V+E PGT + + TD+D N + + G ++ S K + E LDRE+ +S T A D G P ++ +I V V D+NDN P + +Y +YV EN+ + V+ TD DEG N++ +++ E IQ + F V+ + N L D E + +EA D G+P ++ G +N+L D ND P + P G N T +V PR+ G + ++ A+D D+G+N+ L YS N+ N LF M+ +G++ + + Y L++ V+D+G P L TA L +++ ++G
Sbjct: 107 QVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITP------NSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPA--FDQPVYT--VSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS----PRTGRLEVS--GELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSIL------------ECQIQGMSVFTYVSINSENGYLYAL---------RSFDYEQLKDFSFQVEARDAGSP-QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMN-LFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATL--VVQLVDG 681
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH9 (protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]) HSP 1 Score: 281.952 bits (720), Expect = 1.274e-78 Identity = 225/723 (31.12%), Postives = 348/723 (48.13%), Query Frame = 3
Query: 423 VITIERRIDRDNLCHLVPTCCPKKNNQCNLDL-TIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEI--YFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKP-RTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPR 2576
+ T RIDR+ LC + N+C +L + +DF +I + I VKD NDN+P + + E + I + A D D G NG+ +Y + + F L I+ T ++ +L++++ LDRE+ D Y + DGG P + + + V V+D NDN PVF++ + + EN T VIQL A DAD N +I Y + P +LF++ + +G I V+ LD E + V A+D + + TV IN+ D+NDN P I + S ++E + +A+ +V DKD++ NGKV C +E F L+ + Y + T D E + + IV D G P + V V +ED ND P F++ V+E+ + G YL TI+ATD+D G NA + Y + G +A F +++ G + DRE E FT A D+G P S A + V V D NDN P F +V EN + + VTDAD G N ++++++ N F L P +I DRE + Y ++ATD G PP+S+ + INV+DVND P I P SN++ K+ P + G+ +A++ A+D D G N+EL+Y+ S N LF ++P +G I+L++ + V + L+V + D G P+
Sbjct: 85 IFTTSNRIDREKLCA---GASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLD-IVETP----EGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIE--REVPFHLKAV---YDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL-GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILND--------------------------NDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP-SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKG-LFRIDPVTGNITLEEKPAPT-DVGLHRLVVNISDLGYPK 762 HSP 2 Score: 152.91 bits (385), Expect = 6.515e-37 Identity = 166/614 (27.04%), Postives = 260/614 (42.35%), Query Frame = 3
Query: 243 IDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQ------FSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNA---KITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHF----SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLV 2042
+ I E P T VI L A TD + + + Y F + F +N G+IT++R +DR+ T + T+ I V D+NDN P +++ SE + +L D D NG I E+ F L + + ++ ++ LD E ++ F + A D G PS N + V V + DENDN P+F + V +SV+EN + + + A D DS N I YQ+ A F ++ +G + D E V A D G S VI+ + D NDNSP +FT+N ++EN V V +V D D+ EN VT + N+ F L+ P + + K + SFDREQ+S T + D G P ++++ V++ V D+ND +P S S+ V PG+ + + A D D G+NA L Y+I G + +F I+ + G + LE V +D GYPK L T + ++ +ND + Y+Y L T + PL + N+ D+ + +E +T++
Sbjct: 259 VHIPENAPVGTSVIQLHA-------TDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATV------------TINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREV-PFHLKAVYDNQYLLETSS---------LLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGP-----NASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSP-------KFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILN-DNDNFVLD----PYSGVIKSNV--SFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKL-VPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHT--LVLVFLYVNDT---AGNASYIYDLIRRTMETPLDR-NIGDSSQPYQNEDYLTIM 816 HSP 3 Score: 127.872 bits (320), Expect = 3.698e-29 Identity = 141/585 (24.10%), Postives = 254/585 (43.42%), Query Frame = 3
Query: 963 IISVNENLQSNTPV------IQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYI--------------HVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLTVMY-KISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-----KIFSINKLDGKVFLETDLDRESVESLHFTTRAAD-SGYPKQLSTANITVIVKDINDNFPFL-------PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGL-DREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
I ++ E L N P+ + + I+A + + + Y++ ++K A L + S++G I + + E + + +++ ND L + + I ++D NDN+P PS N I EN + S D D+ NG H E + + F L+ + P + ++ ++ DREQK I D G P+++++ + V V D+ND P F E H+ E+ GT + ++ATD D G NA + Y IFG ++F++N G + ++ LDRE T A+D S P + A +T+ V D+NDN P + P + +Y+ E + + + V+D D +N + I+R+ + ++ ++ D + ++ S L D E T ++ I A+D G P + ++ + + D ND P F P S + R + TTI+ A DED GKN+++ Y N F ++ ++G ++ + + ++ V +DNG P L+ A + + +
Sbjct: 27 IYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL--VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIK-----IKIIVKDTNDNAPMF---PSPVIN-ISIPENTLINSRFPIPSATDPDTGFNG--VQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRY-IFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGK---------VICFIEREVPFHLKAVY----------------DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTIS---ATDEDSGKNADIVYQLGPNAS---FFDLDRKTGVLTASRVFDREEQER-FIFTVTARDNGTPPLQSQAAVIVTV 562
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH10 (protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404]) HSP 1 Score: 280.411 bits (716), Expect = 4.500e-78 Identity = 212/673 (31.50%), Postives = 316/673 (46.95%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSF-------------------NGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFG---KDAKIF---SINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLS-TANITVIVKDINDNFP----------------FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKL-IIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLD 2285
Y ++N GV+ + +IDR+ +C P+C L L + ++ + + IEV DINDN P + + +L + SE + G L A D D GTN + Y I+P + F L + ++ LVL+K LDRE+ + +++ A DGG G+ + + V D NDN P F++ VY +S+ EN T VIQL A D D NG++ Y SS P +LF + +G + V ELDYE + V+A D+G + C V++ + D NDN+PEI F T ++E APG +VA+FSV D+DS ENG+V C L + + F R+ Y I T DRE T +V D G P +TS S+ V V D+ND AP FS+ Y +V E+ PG Y++ ++ATD+DEG NA L+YSI + +F SIN +G ++ D E ++ F A D+G P+ L+ A + +++ D NDN P LP+S L L +V DAD+G N+ ++V R +E LFR ++ G+L R R+ YE+VIE D G PP S+ + + ++D
Sbjct: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCV--------LHLEVFLENPL-ELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN-SYFSLDVQTQGDGNRFAE-----LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS----TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCEL--LGDVPF---RLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYL--------LTRVAAVDADDGENARLTYSIV---------RGNE---MNLFRMDWRT-----------GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680 HSP 2 Score: 149.828 bits (377), Expect = 7.300e-36 Identity = 166/613 (27.08%), Postives = 258/613 (42.09%), Query Frame = 3
Query: 900 KVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSG----YIHVRWELDYETYTTISLIVEANDMGNL-------------------RRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKV----TCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKL--FRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVL--DVNDCKPKFIFP-SGSNSTV--KVKPRTV-SGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVC-CYVLIVVVKDNGIPRLEDTARLRIIIESING 2624
+V + V D NDN P F + + ++E+ T A D D N +Y+I T Y L G + + LD E ++ A D G +R T + I + D NDN P F+ +T + EN PG LV + D D +NG+V + H+ P A E F L P T ++S D E+ ++ D G V V V D ND AP S + V+E PGT + + TD+D N + + G ++ S K + E LDRE+ +S T A D G P ++ +I V V D+NDN P + +Y +YV EN+ + V+ TD DEG N++ +++ E IQ + F V+ + N L D E + +EA D G+P ++ G +N+L D ND P + P G N T +V PR+ G + ++ A+D D+G+N+ L YS N+ N LF M+ +G++ + + Y L++ V+D+G P L TA L +++ ++G
Sbjct: 107 QVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI---TPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPA--FDQPVYT--VSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS----PRTGRLEVS--GELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSIL------------ECQIQGMSVFTYVSINSENGYLYAL---------RSFDYEQLKDFSFQVEARDAGSP-QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMN-LFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATL--VVQLVDG 681
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 194.897 bits (494), Expect = 6.910e-50 Identity = 184/753 (24.44%), Postives = 330/753 (43.82%), Query Frame = 3
Query: 384 KSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTI--KSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKL--DGKVF-LETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF--KSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+S F ++ ++G I + + +DR+ L ++ L +T + D S +V+ V D+ DNSP + ++ + E + IG + A D D G NG YS+ N ++ N + + LDRE + V A D G P + V + V D NDN+PVF Y +++ EN+ + +KA D D NGK+ Y ++S + +I+ ++G + +R +D + + I+ ++ A D ST + IN+ D+ND++P + T + E G++ A+ D+DS NG + +E +E+F ++ + I T K DRE ++ + + D G P TS +++V ++DIND AP F +K Y ++E++ G+ + T+ A D DE + ++Y I D ++FSI + G + + +L R+ + A D G + N V + D+N F + + E+ P++ + D D G N+ R V S+ F + P I S LDRE + +++ A+D +PP +T I + + D+ND P+F + S+ + GT+ Q+ AID D G N ++Y S++ + LF ++ SG + + + + + VL + +D G P L + + + + +N
Sbjct: 208 RSQNLFTLDTMSGEIRLAKSMDREVL------------DKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEG----------NGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSG---IGGLTIDYSTGEVTLRERIDAKN-SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAI----DEDSGPNGIIKYSME--GSEDFIIDEDS------GLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQD-HKVRVEISATDQGGLQGRCVVN--VFIDDVNSAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNA---------------------------RIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQF---TSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKL-DREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVN 886 HSP 2 Score: 194.126 bits (492), Expect = 1.208e-49 Identity = 181/610 (29.67%), Postives = 279/610 (45.74%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKIS--TLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLL--PDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVL--DVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
DRE +DK+ V A++ +P+ + S V+V V D DNSP+FEK Y + E+ T V+ + A D DS NG+IEY SL + L +I + SG I LD ET + I L V A+D G +R ST V I + D+NDN+P F + N I EN ++A D+D NGKV H ++ LT+ Y TL+ + S +TA I D P +++ +++ V DIND AP + + E+V G + + A D+D G N ++ YS+ G + F I++ G + LDRE+ A D G P ++ I V++KDINDN P K Y + + E ++ + D DE + K+T Y I++ R+V FS+L D I+ SG + K + I ATD+G +G +NV DVN P F + +VK+ + G + + A D D G N+ + YS S+ F ++P SG IS+ + + + +IV D+ P L + ++ +I++ IN +S
Sbjct: 229 DREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEY---SLGEGNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAP--VFASDSY--NVTILENITIPAVIATVKATDEDFGTNGKV--HYSMASSSGIG------GLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED--FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE----DQKIT---------------YRIEEADREV--------FSILDIGDQGAILSVSGELKRQDHKVRVEISATDQGG----LQGRCVVNVFIDDVNS-APYF---NDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQ----FFRIDPSSGDISVSSDLDREDRA-TFSVIVTASDHASPPLNTSTQIEVILDDINDNS 781 HSP 3 Score: 193.356 bits (490), Expect = 1.840e-49 Identity = 183/631 (29.00%), Postives = 290/631 (45.96%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDK----YEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPL----VQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFR-DVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEY 2429
I V D+NDN+P ++ + E I + A D DFGTNG +YS++ S I T+ YS E RE+ID ++ A DG P+ + ++ + + V D ND++P A +I++ EN+ V ++ AID DS NG I+Y + E ++ F I+ +SG I LD ET SL V A DMG ++ T+ + ++D+NDN+P F+ + N I+E G + +++ D++E+ K+T +E E FS+ + ++ LK Q KV I D+G + V+V ++D+N AP+F++ + + E G + T+ A D D G NA + YSI ++ F I+ G + + +DLDRE + A+D P ++ I VI+ DINDN P S Y + + D+P+ +QV+ DAD G N L +++ P +LFR D T G L + S LDRE + I A DRG P S I + + DVND P F + + + + G+T+ I+A D DEG N+++ +
Sbjct: 363 ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMAS-------SSGIGGLTIDYSTGEVTL--------RERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM------EGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPT--FDKKEY--NVTISEEMPRGS--QIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELK----RQDHKVRVEISATDQGGLQGRCV--VNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI--DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATI---SEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSS---------PSIQLFRLDRTS------------GTLRV-SSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTF---EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISF 929 HSP 4 Score: 181.03 bits (458), Expect = 1.413e-45 Identity = 175/664 (26.36%), Postives = 292/664 (43.98%), Query Frame = 3
Query: 540 FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSY----SIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREV-TTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPK---FIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQ 2504
S + L I V DIND++P + + E IG+ A+D D G NGI YS+ E +II+ ++ + + LDRE +Y V A D G PS N S + V + D NDN+P F+K Y ++++E + + +I LKA+D D + KI Y+I + E + I + V EL + + + + + A D G L+ C V + I D+N ++P YF F+ KI E+ G V +D D +N ++ ++ +++ F ++ + IS DRE ++ + + D +P TS + V ++DIND +P F+ SY ++ED+ GT ++A D D G N ++ Y S ++F +++ G + + + LDRE + A D G P + + IT+ + D+NDN P + Y LY+ EN + + DADEG N++ + L +++ + R I+ + D E K+ ++A+ + S+ + I+V DVND KP F+ V++ I I A D D+ N+ LEY + NDL +GKI ++Q
Sbjct: 459 LSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM-----EGSEDFIIDEDSGLIKTTK--------LLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADR-EVFSILDIGDQGAILSVSGELKRQDHK-VRVEISATDQGGLQ--GRCVVNVFIDDVN-SAP--YFNDHPFS--VKIPEHSPIGYPVITLKAEDHDRGDNARIVYSID--SSQFFRIDPSS------GDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVR-------------------ILTRAEFDYEAKANKFFFELQAS---SGQLSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQM------ARQIGFIPAFDPDQ--NATLEYFL----EENDLIEAEKYTGKILVKQ 1056 HSP 5 Score: 119.398 bits (298), Expect = 9.062e-27 Identity = 141/647 (21.79%), Postives = 273/647 (42.19%), Query Frame = 3
Query: 225 NHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSG--------------YPKQLSTANITVIVKDINDNF--PFL---------------PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIK 2069
+ K + + I EE+PR +++I L A V+ +D K Y+ + + E S+ +I ++++ + R ++++ ++++ V+ + + D+N ++P+++ + + E S IG A D+D G N + Y I+++ + + + LDRE + IV A D +P N S ++ V + D NDNSP F + Y +++E++ T +Q+ AIDAD NG ++Y ++ + +LF ++ SG + V +LD E + I L + A D G + + + + D+NDN+P FE + + + I EN G V +D D +N ++ + A+ + F +E + + +I T FD E +K + + +++ V + V D+ND P + + + ++V+ + I A D D+ NA L Y F ++ + K GK+ ++ + R + F T +D P+ LS + + + D+F P + P I++ ++ H DV + + +TD + + LV E+ L K
Sbjct: 582 DKKEYNVTISEEMPRGSQIITLKA---------VDNDED-QKITYRIEEADREVFSI-LDIGDQGAILSVSGELKR-------------QDHKVRVEISATDQGGLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNA-------------RIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPT--FE--QLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEE-DAEQNGVVRILTRAEFDYE--AKANKFFFELQASSGQLSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPDQ--NATLEY--FLEENDLIEAEKYTGKILVKQEWKRNM--DVSFKTCVSDGANTECSTCRFIHVLVEPEWLSESFTLSLARMTVDDFWDPLVFQRFRDAMSTLSNWKPSDIHVIGVKQHLDDVIYINIAITDHGRVVRGWRAIELVKESIKKLEK 1177
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 193.356 bits (490), Expect = 1.902e-49 Identity = 184/631 (29.16%), Postives = 286/631 (45.32%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDK----YEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPL----VQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFR-DVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEY 2429
I V D+NDN+P ++ + E I + A D DFGTNG +YS++ S I T+ YS E RE+ID ++ A DG P+ + ++ + + V D ND++P A +I++ EN+ V ++ AID DS NG I+Y + E ++ F I+ +SG I LD ET SL V A DMG ++ T+ + ++D+NDN+P F+ + N I+E G + D D E+ K+T +E E FS+ + ++ LK Q KV I D+G + V+V ++D+N AP+F++ + + E G + T+ A D D G NA + YSI ++ F I+ G + + +DLDRE + A+D P ++ I VI+ DINDN P S Y + + D+P+ +QV+ DAD G N L +++ P +LFR D T G L + S LDRE + I A DRG P S I + + DVND P F + + + + G+T+ I+A D DEG N+++ +
Sbjct: 4 ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMAS-------SSGIGGLTIDYSTGEVTL--------RERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM------EGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPT--FDKKEY--NVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEADREVFSILDIGDQGAILSVSGELK----RQDHKVRVEISATDQGGLQGRC--VVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI--DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATI---SEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSS---------PSIQLFRLDRTS------------GTLRV-SSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTF---EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISF 570 HSP 2 Score: 181.03 bits (458), Expect = 1.249e-45 Identity = 175/664 (26.36%), Postives = 293/664 (44.13%), Query Frame = 3
Query: 540 FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSY----SIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREV-TTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPK---FIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQ 2504
S + L I V DIND++P + + E IG+ A+D D G NGI YS+ E +II+ ++ + + LDRE +Y V A D G PS N S + V + D NDN+P F+K Y ++++E + + +I LKA+D D + KI Y+I + E + I + V EL + + + + + A D G L+ C V + I D+N ++P YF F+ KI E+ G V +D D +N ++ ++ +++ F ++ + IS DRE ++ + + D +P TS + V ++DIND +P F+ SY ++ED+ GT ++A D D G N ++ Y S ++F +++ G + + + LDRE + A D G P + + IT+ + D+NDN P + Y LY+ EN + + DADEG N++ + L +++ + R I+ + D E K+ ++A+ + S+ + I+V DVND KP F+ V++ + I I A D D+ N+ LEY + NDL +GKI ++Q
Sbjct: 100 LSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM-----EGSEDFIIDEDSGLIKTTK--------LLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADR-EVFSILDIGDQGAILSVSGELKRQDH-KVRVEISATDQGGLQ--GRCVVNVFIDDVN-SAP--YFNDHPFS--VKIPEHSPIGYPVITLKAEDHDRGDNARIVYSID--SSQFFRIDPSS------GDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVR-------------------ILTRAEFDYEAKANKFFFELQAS---SGQLSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQ------IGFIPAFDPDQ--NATLEYFL----EENDLIEAEKYTGKILVKQ 697 HSP 3 Score: 162.925 bits (411), Expect = 5.015e-40 Identity = 144/578 (24.91%), Postives = 261/578 (45.16%), Query Frame = 3
Query: 903 VIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKL--DGKVF-LETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF--KSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
V + V D NDN+PVF Y +++ EN+ + +KA D D NGK+ Y ++S + +I+ ++G + +R +D + + I+ ++ A D ST + IN+ D+ND++P + T + E G++ A+ D+DS NG + +E +E+F ++ + I T K DRE ++ + + D G P TS +++V ++DIND AP F +K Y ++E++ G+ + T+ A D DE + ++Y I D ++FSI + G + + +L R+ + A D G + N V + D+N F + + E+ P++ + D D G N+ R V S+ F + P I S LDRE + +++ A+D +PP +T I + + D+ND P+F + S+ + GT+ Q+ AID D G N ++Y S++ + LF ++ SG + + + + + VL + +D G P L + + + + +N
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSG---IGGLTIDYSTGEVTLRERIDAKN-SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAI----DEDSGPNGIIKYSME--GSEDFIIDEDS------GLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQD-HKVRVEISATDQGGLQGRCVVN--VFIDDVNSAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNA---------------------------RIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQF---TSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKL-DREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVN 527 HSP 4 Score: 119.013 bits (297), Expect = 1.160e-26 Identity = 141/647 (21.79%), Postives = 273/647 (42.19%), Query Frame = 3
Query: 225 NHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSG--------------YPKQLSTANITVIVKDINDNF--PFL---------------PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIK 2069
+ K + + I EE+PR +++I L A V+ +D K Y+ + + E S+ +I ++++ + R ++++ ++++ V+ + + D+N ++P+++ + + E S IG A D+D G N + Y I+++ + + + LDRE + IV A D +P N S ++ V + D NDNSP F + Y +++E++ T +Q+ AIDAD NG ++Y ++ + +LF ++ SG + V +LD E + I L + A D G + + + + D+NDN+P FE + + + I EN G V +D D +N ++ + A+ + F +E + + +I T FD E +K + + +++ V + V D+ND P + + + ++V+ + I A D D+ NA L Y F ++ + K GK+ ++ + R + F T +D P+ LS + + + D+F P + P I++ ++ H DV + + +TD + + LV E+ L K
Sbjct: 223 DKKEYNVTISEEMPRGSQIITLKA---------VDNDED-QKITYRIEEADREVFSI-LDIGDQGAILSVSGELKR-------------QDHKVRVEISATDQGGLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNA-------------RIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPT--FE--QLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEE-DAEQNGVVRILTRAEFDYE--AKANKFFFELQASSGQLSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPDQ--NATLEY--FLEENDLIEAEKYTGKILVKQEWKRNM--DVSFKTCVSDGANTECSTCRFIHVLVEPEWLSESFTLSLARMTVDDFWDPLVFQRFRDAMSTLSNWKPSDIHVIGVKQHLDDVIYINIAITDHGRVVRGWRAIELVKESIKKLEK 818
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 151.754 bits (382), Expect = 1.205e-36 Identity = 188/769 (24.45%), Postives = 341/769 (44.34%), Query Frame = 3
Query: 327 NKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSV--QDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEG-----NPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
K ++ P Y F F E++S + +++ +G I+ + HL + D+ ++ I +++EV D NDN+P ++ + + SE +++G S +L D D + + I + ++ + + + + Q LV+ +LDRE DKYE ++ A DGG P+ G ++ + + D NDN+PVF ++ Y SV+ N+ + +I ++A DAD N +I Y I + P + F+I S SG I L +T +IV A+D G+ S+ V I + +SP + +N+A + EN G +VA S+ Q +D+ + L P ++ ++ L ++ I DRE S+ + +G +P+ T G DIND AP + S H++ + G T+ A D D G N + YS+ D ++ SI+K G++F+ +D + F RA D G P + + + D P K+++ + + E+ LV+V ++ G + + +L + +DE+ L D G + I+++ D E Y+ + AT+ + +++ +I I + DVND P F +P+ + TV+ P+ + + A D D G E+ Y S + + F +NP +G++ Q+ + + L+V KD G E++A + I +
Sbjct: 46 GKREESAAPKY-FVVFPDEQTSKFLKVDERSGEIS--------TIAHL------DYEKRSKFDIVAVKVEESGETIDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVI----LQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSN-FAI-SQSGVITTTASL--LPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLIGSSALCPQQTDQ-----AHVYLLLLCGI-----LDRETASEHHLKFLLEKDGQIIIEHPQLLTIG-------DINDNAPQW--HSSQIHISLNRTQGGSR-TLTAKDPDLGQNGWIRYSVL--DTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL---------QNQDEH----LTVDTMS------------GTVCIQKT-FDFEKQKSYQTTVIATNANS--ETSTSLISIRLKDVNDNWPIF-YPNEYHLTVREGPKPEEPLLV--VSASDMDSGTFGEVSYHILSESSS---FSINPVTGEVFAQKPLARGR----FHLVVSAKDGGGQSSENSANIHITV 731 HSP 2 Score: 127.872 bits (320), Expect = 2.374e-29 Identity = 129/491 (26.27%), Postives = 219/491 (44.60%), Query Frame = 3
Query: 555 VLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGST--CTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNS 2021
++ I +KD+NDN P + NE EG + + + A D D GT G Y I E + F ++ + +++ K + ++ +V+A DGG S S + + V D++ +P F ++ Y I E++ P I + ++ A S K++Y I S + FSI+ ++G I+V LD + + T+ L ++A L G + V+I I D NDN P+ S I E+ + V DKD +NG+V + I++ S ++ ++ST D E + D G P ++++ ++ + V D+ND AP F + Y V E+ P T + + A DKD N + Y I ++ F I++ G V+ + +DRE + + + A D G P + STA+ + V D+NDN P + V + + D D+GLN
Sbjct: 626 LISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSSFSINPVTGE---VFAQKPLAR------------GRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDI---LPGIAIGSVGAMS----KVKYSIYSGDQDHN---FSIDEDTGKIYVTRYLDADVHDTVLLNIQA----TLPSGESNQTQVVIFIEDHNDNPPQF----SSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSI--ISSHPGSSIEID---QFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRI-TNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNG 1077 HSP 3 Score: 125.946 bits (315), Expect = 1.036e-28 Identity = 155/601 (25.79%), Postives = 251/601 (41.76%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAV--------FSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHI-VCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKD-AKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKL--IIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTI---QESHKVCCYVLIVVVKDNGIPR 2576
D EK Y+ V A + + + I + + D NDN P+F Y ++V E + P++ + A D DS G++ Y I S + FSI +G + + L + L+V A D G ++ + I + D + +P+ SR + TE+ PG + +S+ D + N FS++ KI + D + V +I G QT V + +ED ND P FS + ED+K + + A+DKD+ N + YSI I++ G++ + LD E+ + +A D G P + S + + V D+NDN P KS Y + VLEN + +V D D N + I EY F + D KL + + +DREV + +I I A D+G PP+S+ I+VLDVND P + S + + V + T I I+A+D D+G N + Y ++ Q++ LF++ +G + L++ + E H+ L V+V D G+PR
Sbjct: 602 DFEKQKSYQTTVIATNANSETSTSLISI--RLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILS-----ESSSFSINPVTGEVFAQKPLARGRF---HLVVSAKDGGGQSSENSANIHITVIDKDTKTPQF----SRSKYEIRTTEDILPGIAIGSVGAMSKVKYSIYSGDQDHN--------------FSIDEDT------GKIYVTRYLDADVHDTVLLNIQATLPSGESNQT---QVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQI---------VYRITNGSEY-----------------FGI--DEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCL----SITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLY--RAQLQSS-LFVVK-SNGDVYLRRQLNASDERHQ----RLSVIVSDQGVPR 1125 HSP 4 Score: 92.4337 bits (228), Expect = 1.654e-18 Identity = 150/644 (23.29%), Postives = 267/644 (41.46%), Query Frame = 3
Query: 717 ISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDIN-DEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPD-GKLIIRE---SGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINV--LDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+ PE+ S + +S + + +LDRE +++Y V G +V V V + NDN P F + V ENL+ + V + A D D+ + Y + S + + F+I+ +G IH+ LD+E +L ++A D G+ + T+ ++ D+NDN+P + +P T + T +PG+ A D D+ G +T L ++ F + P + + L VTA D G P +TS VSV + + + P F + + F V E+ K G + ++ + E Y I +A KIFSI+K G++F+ +DRE + F + Q VIV D NDN P F + YL + ++ + Q+ +D D G N ++S ++ +L PD G + + E + LD ++I++EA D G+P ++ G + +++ + P F+ P V V T GT + +I A + +N L YS K + ++ ++G+++L+ + + + + V NG L+I++E ++
Sbjct: 1854 LQPELAGLTYSIVEGNIDSAFSVDSEGVIRTNLELDREILERYSLKVIGTGSGQ---QIGTRVDVRVNNLNDNVPSFPMS-KPRRVPENLRVGSYVATVGAKDVDNL--APLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATD-GSFDTFTNLTIFVS--DINDNAP-TFSKPLYQTTVSPATF--SPGQPFAKIEAHDLDAR--GALTYSLGQGSSSIFRVA----PESGALFMKVLPPAGERYLVTVTAT----DNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESRE-----FHYRIQDPEASKIFSIDKF-GRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIV------------------------TLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPV---YEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGK---LGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG---RSAVVPLKIVVEPVD 2436 HSP 5 Score: 90.5077 bits (223), Expect = 5.970e-18 Identity = 111/399 (27.82%), Postives = 180/399 (45.11%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI-------SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPE-IYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSV----GVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALL 1718
+VI ++D NDN P +S + + E ++ + + A D D NG YSI S EI +F + ++T +++ D E Y+ V A D G P + ++ + + V D NDN+P FEK+ Y + V EN T V ++ A D DS NG+I Y+I++ + EY F I+ G ++ + +D E + + + + A D G R ST + I++ D+NDN P + P + ++ A G +VA+ D D NG V A + SL + V + S +R Q+ V + D+G PR++ V V G DI + P + YI + + G L T+NAT G+++ L
Sbjct: 823 VVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQF--TGQLSTGSLL---------------DYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGS--EY---FGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLS--TAIGTIVAM----DPDKGLNGSVLYR----AQLQSSLFVVKSNGDVYLRRQLNASDERHQRLSV----IVSDQGVPRKSVVCHVPVRISKGSADIQIQEPF---QKYI-EIPKSCPTGCRLTTLNAT----GVSSWL 1177 HSP 6 Score: 86.6557 bits (213), Expect = 1.002e-16 Identity = 84/345 (24.35%), Postives = 150/345 (43.48%), Query Frame = 3
Query: 906 IVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY 1940
++ + D NDN+P + + IS+N + L A D D NG I Y + +L SI+ +G I V +D + I V A D G+ + V+ ++ D P+ FE + + +I E+ G + + + ++ L+ +E +++ M+ + + K+FD E++ ++ + + +T++ +S+ ++D+ND P F Y V E KP L ++A+D D G +SY I + + FSIN + G+VF + L R H A D G ++ANI + V D + P +S Y
Sbjct: 428 LLTIGDINDNAPQWHSSQIHISLNRTQGGSR---TLTAKDPDLGQNGWIRYSVLD------TELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQ--FEKALW--QVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQN-QDEHLTVDTMSGTVCIQ------KTFDFEKQKSYQTTVIATNANS--ETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS-FSINPVTGEVFAQKPLAR---GRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKY 746 HSP 7 Score: 83.1889 bits (204), Expect = 1.199e-15 Identity = 101/407 (24.82%), Postives = 167/407 (41.03%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYI-ISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPS-RFTNNAKITENEAPGKLVAVFSVQDKDSN-ENGKVTCHLEP-IANEEFSLERMNIPLTVMYK----ISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKD--EGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHT--ADVPLVQVNVTDAD 2006
DRE ++ I+ DGG S N S V V V D+NDN P + + + + E+ + + + +A D D NGK +++ +E +SG ++ L+ E D+ R S + I +R ++ P +Y E + +N TE +AP + + + D G+ L+P +A +S+ NI I T DRE + + ++ G Q V V V ++ND P F S V E+++ G+Y+ T+ A D D + L G+ F+I++ G + L LD E + T +A D + + N+T+ V DINDN P K +Y + T P ++ D D
Sbjct: 1688 DREASQEHLLIIILTDGG--SRNDSCTVRVTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFEL-------------LEDSSG--------------SLDLVPETGDLVLRRLSSLQSWKIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQPELAGLTYSIVEGNIDSAFSVDSEGVIRTNLELDREILERYSLKVIGTGSG---QQIGTRVDVRVNNLNDNVPSFP-MSKPRRVPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSFD---TFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLD 2058 HSP 8 Score: 75.0998 bits (183), Expect = 3.146e-13 Identity = 84/375 (22.40%), Postives = 162/375 (43.20%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHV-RW---ELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKIS--TLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDL-DRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL 1925
DRE+ +EF V + S K V V DENDN PVF Y +S+ +++ + Q+ A D DS NG++ Y+I S + ++ ++G I + W +LD T ++VEA D G+ R + V ++++ + + +F + + E+ + G ++ ++ N + +SL+ L + K TLK+ + + + + +GN R + + VE +++ AP F++ SY + G + + A D+D G++ ++ YSI + + + I + G + L+ L R ++ T A S + +T + + D+ + P L
Sbjct: 2189 DREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGND---LNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVY--EVHVLEDTSVGTVLQKIRASNRLGMRNDGLL----------YSLKEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNGRSAVV-PLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISDRQSTV-KIEEHTGIIRLQKPLVSRRNLTIEQITVVAYSSPTKQSKTTVYLEIGPFDVQPSLPKL 2546 HSP 9 Score: 63.929 bits (154), Expect = 7.444e-10 Identity = 85/339 (25.07%), Postives = 137/339 (40.41%), Query Frame = 3
Query: 1605 PHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKD--AKIFSINKLDGKVFLETDLDRESVESLHFTT-RAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
P F + F V E + GT + I+ K E A + +F + +K +++ G++ LD E + +SG T +I V V D NDN P F + + L + E VTD D + ++ + K ++L D L+ +G+L DRE KYE++IEA D G P K + I ++D ND P F S S T V G+ + + A D D G+NS + Y K + ++ +SG I+ ++ + + +IVV D+G P L +A + I +
Sbjct: 20 PTFCQCLTKFTVPESAQIGTRIGWISG--KREESAAPKYFVVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEESG-----ETIDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQAD-----------LVVNGQL-------DREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVF---SRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAISQSGVITTTASLLPA---STHDVIVVASDHGSPSLSSSAVVTITV 327
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 150.599 bits (379), Expect = 2.984e-36 Identity = 225/857 (26.25%), Postives = 371/857 (43.29%), Query Frame = 3
Query: 279 VIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDK----YEFIVNAFDGGNP-SFNGSIKVIVAVTDENDNSPVF-EKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAK--LFSIESNSGYIHVRWELD----YETYTTISLIVEANDMGNL------RRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEA---PGKLVAVFSVQDKDSNENGKVTCHL---EPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI---------FGKDAKIFS-INKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQL-STANITVIVKDINDNFPFLPKS----IYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNS-----TVKVKPRTVSGTTIAQIIAIDED-EGKNSELEYSF--KSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRL-------EDTARLRIIIESINGDSILSKENKMKDNVEYSNEES 2687
V+D+ AQ+ + F +K G Y + E + +F I+P G+I + R +D D+ PK + L +T + D+ SH+ L I + D+NDN P +++ Q E + + A+D D G N YS+ N N + SN E + K +LD +++++ Y F V A D G P S + S + + + ND S VF + Y V E+ Q TPVIQ++A DAD + ++ Y K LFSI+ ++G + +R + E I+L V D G+ S T++I I D+N+N PE + + +++++ AKI E P +V V D DS+ NG + L + + + F ++R LT + FDRE + + + D G+ SV V DIND +P F SY V+ GT + T+ A D D NA ++YS+ D F +N+ G++ L + ++ + F A D+G P+ L S+A +T+ V D P S + V EN + +++ + + NS+ L TA+ K E FR K F N + +++I E GLD E Y + + ATD + STK + + V DVND P+F + + T +G I + AID D +G +E+ Y ++N + F ++ +G+I + + K+ Y+L V D + L +D +++I+I +N ++ +E K V+ S E
Sbjct: 549 VVDVKAQSFRSFEDGRSK----GPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDD------PALPKLHK---LKVTAREDNRESHVD-LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVD------------NHNFSINSNGE---ISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRD---EVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPE-FPDCAKYSDIAKIMEGTYKTDPPTIVKV-EATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHV----VFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKT-QKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKL---TASGGPGNKAE----SKFRQFNK-FENGNEWV----EVVIME-GLDYEQVNNYTLTLTATDMTSRVASTKTFV-VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKF-DREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEG 1351 HSP 2 Score: 139.043 bits (349), Expect = 1.075e-32 Identity = 159/608 (26.15%), Postives = 258/608 (42.43%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFD-------GGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPI-ANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAH---IVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKP----GTYLFTINATDKDEGI--NALLSYSIFGK----DAKIFSINKLDGKVFLETDLDRESVESLHFT--TRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTK---YEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDN 2564
DREKID Y V A D G N ++KV + + D NDN+P FE+ YI V E+ VI +KA D D N + Y + F + ++SG I V+ LD+E L++ A+D R +T V I+I D+NDN+P+ FE ++ + + P L V + ++ ++ LE A+E F + + + I +K+ DR+ + V + + D+ V V V DIND +P F E+ + + + E+ +P G Y + A D D+ NA + Y I +F I++ GK+F LDRE F RA D G P + AN+T+ V D+NDN PF K+ Y V E ++ + DADE +SE + D +D +S L P LD E T+ + + I +D + + +++ ++D ND P G+ +V+ GT+I + A D D G + + +S+ + F ++ + G + + T+ + + Y LI+ DN
Sbjct: 1287 DREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSN--LRYHLIGAGGGRIP--FGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG---RHNATTNVYIHIEDVNDNAPQ--FEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYS------GTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGY-IEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTD--------KDSKQSSVGVLRVKQP----------LDYEDVTQRDGFHLGIRVSDGRH---DAEAAVHVALVDRNDHAPHI---HGATEH-RVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQ--FTID-QDGTLRVAHTL-DREDIAVYNLIIEAYDN 1849 HSP 3 Score: 122.865 bits (307), Expect = 9.887e-28 Identity = 162/647 (25.04%), Postives = 276/647 (42.66%), Query Frame = 3
Query: 828 EKIDKYEFIVNAFDGGNPSFNGS-----IKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAID----ADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSK----VTAHIVCFDEGNPRQ-TTSGSVSVGVEDINDEAPHFSEKS-YIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK------IFSINKLDGKVFLETDLDR----ESVESLHFTTRAADSG----YPKQLSTANITVIV--KDINDNFPFLPK----SIYLYVLEN-HTADVP-LVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGL---------DREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFK-----SNNQTNDL---FLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPR-LEDTARLRI 2603
E+ D Y A D +PS N + + ++ + DE P F K Y ++V+E+ + V+ +KA D G I Y + T + K F I+ ++G IH+ LD++ L R S + I I D+NDN P +R A++ E+ + + + DKD+ +N ++T +S++ N + +IS D +Q ++ ++ D G P ++S + + E+ NDE+ F S Y V ED + GT + I A D D ++YS K+ + +FSI++ G V L + E+ ++ T D G YP + T+ T+++ +D+N+N P P S ++E + D P +V+V TD D N + +L T+S S F +I R++G+ DRE + ++ ++ATDRG+ P + V+D+ND P+F PS S + + GT++ + A D D N+E+ YS + NDL L+N SG+I+L + I K ++ V+ DNGIP L+ +A++ +
Sbjct: 489 ERGDTYRISAQAMDL-SPSDNTTSQLSEVAILEILADER--PPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTF----TRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRIT----------YSVDNHNFSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRD---EVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLY----------------------YTQSESRKAF-------VIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFE---AVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPI--PMKTQKFIFNVIADDNGIPEALQSSAQVTL 1081 HSP 4 Score: 107.842 bits (268), Expect = 3.867e-23 Identity = 182/742 (24.53%), Postives = 306/742 (41.24%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISV-NENLQSNTPVIQLKAIDADS-EMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTI---SLIVEA-NDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVF--SVQDKD----SNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSK--VTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDE-GINALLSYSI----------FGKDAKIFSINKLDGKVFLETDLDRESV---ESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPK-FIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGK-----NSELEYSFKSNNQTNDLFLMNPESGKISLQQT-IQE 2516
+F I+ L G I + DR+ + + T + L + D + +++ D+NDN+P + + + + + E G A D D +N + Y+ I ++ T+ LD E D+Y ++ A DG N + V + + D NDN+P FE+ Y +V E++ + + A DAD E + +I Y++ E +F I SG I + LD + + + +V+A +D GN G V +N+RD+NDNSP I+ P R I EN P V+ VQ +D + EN + + + N+ + E + KI ++S DRE S+ + D G P + +V++ V D+ND AP F + Y V E G + + +A D DE + + +Y + KD+K S+ G + ++ LD E V + H R +D + + A + V + D ND+ P + + V E+ + + TD D G +TA I R+ + Q F++ DG L + + LDRE Y ++IEA D N + ++ + + DVND P+ + P + + V+ +I A D D + E+ SFK + N +F N + G S+ T +QE
Sbjct: 1270 HFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVI---NDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSN-LRYHLIGAGGGRIPFGVRTDSGTIFVKEP----------LDFEASDQYHLVLIASDG---RHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADE---VFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVG-YADVQVNVRDINDNSP-IF--PERLF--GYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGI--VRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSV----GVLRVKQPLDYEDVTQRDGFHLGIRVSDG---RHDAEAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGRYTATDRDAG-----------DTARFRINRQSDPKRQ--------------FTIDQDGTLRVAHT-LDREDIAVYNLIIEAYDNSN--NIGRQMVAVYLQDVNDNGPEPYTVP---RPCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQE 1945 HSP 5 Score: 105.531 bits (262), Expect = 1.641e-22 Identity = 181/825 (21.94%), Postives = 334/825 (40.48%), Query Frame = 3
Query: 345 GKPIYKFQFFNCEKSSVYFEINPLNG-------VITIERRIDRDNLCHLVPTC-CPKKNNQCNLDLTIKSDDD--------FSHIIVLVIEVKDINDNSPFW---SQNELVTQFSEGSEIGDSKSLTV--ALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEY--QISSLTKPEYAKLFS----IESNSGYIHVRWELDYETYTTI-SLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPS---RFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNI--PLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKP--------GTYLFTINATDKD-EGINALLSYSIF----GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTAN--------ITVIVKDINDNFPFLPKSIYL-YVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEG-KNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQES--HKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKE 2645
G P+ + Q + ++ V + NG + +I+ L H V + N NL + ++ D + L+I ++D+N+N P + ++ + + EG+ D ++ A D+D NG YS+ +E +++I+ T + + + DRE + + V A D G+ G + V V D NDNSP FE+ Y SV+ T VI + A D D+ N +I Y +I + E+ + SG I + + +T I ++I + N + + S+ V +N+ D +P+ P T + + N+ + AV S ++S+ K+T P E + N ++ ++ D EQ + T + D R ++ + V V D+ND P F+ + ++E++ P G + T+ A D D +G + Y I G++ K F I++L G++F DRE ++ T A+D L AN + +++ D+NDN P + Y+ V E+ ++ + D D+ +S + L+ + F + D I + LD E + +Y +V+ A+D G +T +YI++ DVND P+ F +T ++ + + A D D+ K+S + Y + +++F + SG I L + + V + +V D+ L A +++ + IN +S + E
Sbjct: 764 GTPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVF------DRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQ-SSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSV-SALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDK--HSNLRYHLIGAGGGRI-----------------------PFGVRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNATTN--VYIHIEDVNDNAPQ--FEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQG-ADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE 1548 HSP 6 Score: 91.2781 bits (225), Expect = 3.750e-18 Identity = 121/476 (25.42%), Postives = 200/476 (42.02%), Query Frame = 3
Query: 318 TDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIV----LVIEVKDINDNSPFWSQNELVTQFSEGSEI--GDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFI--VNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKI-EYQISSLTKPEYAKL--FSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGN--PRQTTSGSVSVGVEDINDEA--PHFSEKSYIFHVNEDV-KPGTYLFTINATDKD 1697
TD ++ + + +Y+ + + + F I +G I + + +DRD P P N +++ DD + +V + + V+DINDNSP + + L E E D DF +I I +L IN ++ ++ K+ + LDRE + EFI V A D G PS G V + VTD NDN+P FEK Y SV E V+ A DAD E + YQ+S + Y S +S+ G + V+ LDYE T + + R + V + + D ND++P I+ ++ E+ G + ++ D+D+ + + + + +F++++ + + DRE + I +D N RQ V+V ++D+ND P+ + IF N V + GT I ATD+D
Sbjct: 1462 TDADQDEKSSRIVYRLE---GQGADEVFRIGKYSGTIELVKALDRDP-----PAGVPSWN------FVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE-RLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKL---INGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPHIH-----GATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGT-------LRVAHTLDREDIAVYNLIIEAYDNSNNIGRQM----VAVYLQDVNDNGPEPYTVPRPCIFRENTPVNQLGT--CEIRATDRD 1901
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 150.599 bits (379), Expect = 2.984e-36 Identity = 225/857 (26.25%), Postives = 371/857 (43.29%), Query Frame = 3
Query: 279 VIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDK----YEFIVNAFDGGNP-SFNGSIKVIVAVTDENDNSPVF-EKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAK--LFSIESNSGYIHVRWELD----YETYTTISLIVEANDMGNL------RRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEA---PGKLVAVFSVQDKDSNENGKVTCHL---EPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI---------FGKDAKIFS-INKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQL-STANITVIVKDINDNFPFLPKS----IYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNS-----TVKVKPRTVSGTTIAQIIAIDED-EGKNSELEYSF--KSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRL-------EDTARLRIIIESINGDSILSKENKMKDNVEYSNEES 2687
V+D+ AQ+ + F +K G Y + E + +F I+P G+I + R +D D+ PK + L +T + D+ SH+ L I + D+NDN P +++ Q E + + A+D D G N YS+ N N + SN E + K +LD +++++ Y F V A D G P S + S + + + ND S VF + Y V E+ Q TPVIQ++A DAD + ++ Y K LFSI+ ++G + +R + E I+L V D G+ S T++I I D+N+N PE + + +++++ AKI E P +V V D DS+ NG + L + + + F ++R LT + FDRE + + + D G+ SV V DIND +P F SY V+ GT + T+ A D D NA ++YS+ D F +N+ G++ L + ++ + F A D+G P+ L S+A +T+ V D P S + V EN + +++ + + NS+ L TA+ K E FR K F N + +++I E GLD E Y + + ATD + STK + + V DVND P+F + + T +G I + AID D +G +E+ Y ++N + F ++ +G+I + + K+ Y+L V D + L +D +++I+I +N ++ +E K V+ S E
Sbjct: 549 VVDVKAQSFRSFEDGRSK----GPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDD------PALPKLHK---LKVTAREDNRESHVD-LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVD------------NHNFSINSNGE---ISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRD---EVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPE-FPDCAKYSDIAKIMEGTYKTDPPTIVKV-EATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHV----VFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKT-QKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKL---TASGGPGNKAE----SKFRQFNK-FENGNEWV----EVVIME-GLDYEQVNNYTLTLTATDMTSRVASTKTFV-VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKF-DREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEG 1351 HSP 2 Score: 139.043 bits (349), Expect = 1.075e-32 Identity = 159/608 (26.15%), Postives = 258/608 (42.43%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFD-------GGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPI-ANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAH---IVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKP----GTYLFTINATDKDEGI--NALLSYSIFGK----DAKIFSINKLDGKVFLETDLDRESVESLHFT--TRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTK---YEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDN 2564
DREKID Y V A D G N ++KV + + D NDN+P FE+ YI V E+ VI +KA D D N + Y + F + ++SG I V+ LD+E L++ A+D R +T V I+I D+NDN+P+ FE ++ + + P L V + ++ ++ LE A+E F + + + I +K+ DR+ + V + + D+ V V V DIND +P F E+ + + + E+ +P G Y + A D D+ NA + Y I +F I++ GK+F LDRE F RA D G P + AN+T+ V D+NDN PF K+ Y V E ++ + DADE +SE + D +D +S L P LD E T+ + + I +D + + +++ ++D ND P G+ +V+ GT+I + A D D G + + +S+ + F ++ + G + + T+ + + Y LI+ DN
Sbjct: 1287 DREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSN--LRYHLIGAGGGRIP--FGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG---RHNATTNVYIHIEDVNDNAPQ--FEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYS------GTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGY-IEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTD--------KDSKQSSVGVLRVKQP----------LDYEDVTQRDGFHLGIRVSDGRH---DAEAAVHVALVDRNDHAPHI---HGATEH-RVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQ--FTID-QDGTLRVAHTL-DREDIAVYNLIIEAYDN 1849 HSP 3 Score: 122.865 bits (307), Expect = 9.887e-28 Identity = 162/647 (25.04%), Postives = 276/647 (42.66%), Query Frame = 3
Query: 828 EKIDKYEFIVNAFDGGNPSFNGS-----IKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAID----ADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSK----VTAHIVCFDEGNPRQ-TTSGSVSVGVEDINDEAPHFSEKS-YIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK------IFSINKLDGKVFLETDLDR----ESVESLHFTTRAADSG----YPKQLSTANITVIV--KDINDNFPFLPK----SIYLYVLEN-HTADVP-LVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGL---------DREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFK-----SNNQTNDL---FLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPR-LEDTARLRI 2603
E+ D Y A D +PS N + + ++ + DE P F K Y ++V+E+ + V+ +KA D G I Y + T + K F I+ ++G IH+ LD++ L R S + I I D+NDN P +R A++ E+ + + + DKD+ +N ++T +S++ N + +IS D +Q ++ ++ D G P ++S + + E+ NDE+ F S Y V ED + GT + I A D D ++YS K+ + +FSI++ G V L + E+ ++ T D G YP + T+ T+++ +D+N+N P P S ++E + D P +V+V TD D N + +L T+S S F +I R++G+ DRE + ++ ++ATDRG+ P + V+D+ND P+F PS S + + GT++ + A D D N+E+ YS + NDL L+N SG+I+L + I K ++ V+ DNGIP L+ +A++ +
Sbjct: 489 ERGDTYRISAQAMDL-SPSDNTTSQLSEVAILEILADER--PPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTF----TRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRIT----------YSVDNHNFSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRD---EVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLY----------------------YTQSESRKAF-------VIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFE---AVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPI--PMKTQKFIFNVIADDNGIPEALQSSAQVTL 1081 HSP 4 Score: 107.842 bits (268), Expect = 3.867e-23 Identity = 182/742 (24.53%), Postives = 306/742 (41.24%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISV-NENLQSNTPVIQLKAIDADS-EMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTI---SLIVEA-NDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVF--SVQDKD----SNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSK--VTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDE-GINALLSYSI----------FGKDAKIFSINKLDGKVFLETDLDRESV---ESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPK-FIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGK-----NSELEYSFKSNNQTNDLFLMNPESGKISLQQT-IQE 2516
+F I+ L G I + DR+ + + T + L + D + +++ D+NDN+P + + + + + E G A D D +N + Y+ I ++ T+ LD E D+Y ++ A DG N + V + + D NDN+P FE+ Y +V E++ + + A DAD E + +I Y++ E +F I SG I + LD + + + +V+A +D GN G V +N+RD+NDNSP I+ P R I EN P V+ VQ +D + EN + + + N+ + E + KI ++S DRE S+ + D G P + +V++ V D+ND AP F + Y V E G + + +A D DE + + +Y + KD+K S+ G + ++ LD E V + H R +D + + A + V + D ND+ P + + V E+ + + TD D G +TA I R+ + Q F++ DG L + + LDRE Y ++IEA D N + ++ + + DVND P+ + P + + V+ +I A D D + E+ SFK + N +F N + G S+ T +QE
Sbjct: 1270 HFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVI---NDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSN-LRYHLIGAGGGRIPFGVRTDSGTIFVKEP----------LDFEASDQYHLVLIASDG---RHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADE---VFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVG-YADVQVNVRDINDNSP-IF--PERLF--GYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGI--VRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSV----GVLRVKQPLDYEDVTQRDGFHLGIRVSDG---RHDAEAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGRYTATDRDAG-----------DTARFRINRQSDPKRQ--------------FTIDQDGTLRVAHT-LDREDIAVYNLIIEAYDNSN--NIGRQMVAVYLQDVNDNGPEPYTVP---RPCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQE 1945 HSP 5 Score: 105.531 bits (262), Expect = 1.641e-22 Identity = 181/825 (21.94%), Postives = 334/825 (40.48%), Query Frame = 3
Query: 345 GKPIYKFQFFNCEKSSVYFEINPLNG-------VITIERRIDRDNLCHLVPTC-CPKKNNQCNLDLTIKSDDD--------FSHIIVLVIEVKDINDNSPFW---SQNELVTQFSEGSEIGDSKSLTV--ALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEY--QISSLTKPEYAKLFS----IESNSGYIHVRWELDYETYTTI-SLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPS---RFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNI--PLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKP--------GTYLFTINATDKD-EGINALLSYSIF----GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTAN--------ITVIVKDINDNFPFLPKSIYL-YVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEG-KNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQES--HKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKE 2645
G P+ + Q + ++ V + NG + +I+ L H V + N NL + ++ D + L+I ++D+N+N P + ++ + + EG+ D ++ A D+D NG YS+ +E +++I+ T + + + DRE + + V A D G+ G + V V D NDNSP FE+ Y SV+ T VI + A D D+ N +I Y +I + E+ + SG I + + +T I ++I + N + + S+ V +N+ D +P+ P T + + N+ + AV S ++S+ K+T P E + N ++ ++ D EQ + T + D R ++ + V V D+ND P F+ + ++E++ P G + T+ A D D +G + Y I G++ K F I++L G++F DRE ++ T A+D L AN + +++ D+NDN P + Y+ V E+ ++ + D D+ +S + L+ + F + D I + LD E + +Y +V+ A+D G +T +YI++ DVND P+ F +T ++ + + A D D+ K+S + Y + +++F + SG I L + + V + +V D+ L A +++ + IN +S + E
Sbjct: 764 GTPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVF------DRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQ-SSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSV-SALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDK--HSNLRYHLIGAGGGRI-----------------------PFGVRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNATTN--VYIHIEDVNDNAPQ--FEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQG-ADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE 1548 HSP 6 Score: 91.2781 bits (225), Expect = 3.750e-18 Identity = 121/476 (25.42%), Postives = 200/476 (42.02%), Query Frame = 3
Query: 318 TDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIV----LVIEVKDINDNSPFWSQNELVTQFSEGSEI--GDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFI--VNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKI-EYQISSLTKPEYAKL--FSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGN--PRQTTSGSVSVGVEDINDEA--PHFSEKSYIFHVNEDV-KPGTYLFTINATDKD 1697
TD ++ + + +Y+ + + + F I +G I + + +DRD P P N +++ DD + +V + + V+DINDNSP + + L E E D DF +I I +L IN ++ ++ K+ + LDRE + EFI V A D G PS G V + VTD NDN+P FEK Y SV E V+ A DAD E + YQ+S + Y S +S+ G + V+ LDYE T + + R + V + + D ND++P I+ ++ E+ G + ++ D+D+ + + + + +F++++ + + DRE + I +D N RQ V+V ++D+ND P+ + IF N V + GT I ATD+D
Sbjct: 1462 TDADQDEKSSRIVYRLE---GQGADEVFRIGKYSGTIELVKALDRDP-----PAGVPSWN------FVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE-RLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKL---INGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPHIH-----GATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGT-------LRVAHTLDREDIAVYNLIIEAYDNSNNIGRQM----VAVYLQDVNDNGPEPYTVPRPCIFRENTPVNQLGT--CEIRATDRD 1901
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 257.299 bits (656), Expect = 2.443e-69 Identity = 223/814 (27.40%), Postives = 370/814 (45.45%), Query Frame = 3
Query: 246 DIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGIS-YYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTIS---------LIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKIT---ENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNP-PKSTKGIIYINVLDVNDCKPKFIFP-------SGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQES-HKVCCYVLIVVVKDNGIPRLEDTARLRIIIES 2615
++ E PR T V + PT KP + ++F + F ++P+ G + +DR+ + + + DL + S ++ I + I+V D+NDNSP + + + FSE + G L A D D G NG++ Y I + + + N + L L LDRE Y+ ++A DGG+P G ++V V + D NDN P+F+ + Y +S+NE TPV+ + A D D N KI Y ++ E F++ +G I ++ T + V A D G+ R+ V +N+ D ND+ P I F F + K+ EN G +VA +V+D DS NG+ + + ++ E R+ ++ + DRE+ K +V D+G P +TT+ + + V D+ND P F + Y ++E G+++ +I ATD+D G+NA + Y I G + K FS++ L G + LDRE +++ + A D G + + + VI+ D ND P F + + + E+ + + TD D+G N L ++R YP+Q +T G+L R LDRE ++YEI + A D+G P P+S +++NV DVND P+F +P + + +K+K + + A D+D+G N+ +EY +S + LF ++ SG ISL+ S H Y L+V +D G R + A + I+++S
Sbjct: 72 EVLEGQPRGTTV--------GFIPT---------KPKFSYRFNEPPRE---FTLDPVTGEVKTNVVLDREGM-------------RDHYDLVVLSSQP-TYPIEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPS--GDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLA-----ETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFR--FFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRI--VSGNELGHFRLE-EAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPS-----VERL--YPLQFALDALT-------------GQLTTRRP-LDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQF-YPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGE--GLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKS 815 HSP 2 Score: 213.386 bits (542), Expect = 1.885e-55 Identity = 216/751 (28.76%), Postives = 338/751 (45.01%), Query Frame = 3
Query: 486 PKKNNQCNLD-LTIKSDDDFSHIIVLVIEVKDINDNSP-FWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYS-NKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMG-NLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAP--GKLVAVFSVQDKDSNE-NGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPK-QLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTK------YEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK--VKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKENKMKDNVEYSNEES 2687
P+K Q + L + S + + I +KD+ND P F S NE T E I A+DND G NG Y + E + ++ ++ + +S N +L + LDRE Y + A D G P + ++++ + DENDNSPVF+ Y SV EN V+Q+ A D D NG+I Y S+ + FSI ++G + V L+YE + SL V A D G T + INI D+NDN P P A++ EN P G V + D D+ N +V L+ ++ F R+N I+ LK DREQ+S+ T +V D G+P T +G V V V+DIND P F +SY V E++ GT++ T ATDKDEG+NA L +++ G+ F I+ G++ T LDRE H T A DS + + S+ N+T+ V D+NDN P + Y + V E + + D D+G N+ T I +D++ + D+ K + + L+ + TK Y IVI A D+G S+K + + +L + P F + + S+ + V+P G I ++ A +G ++ Y+ + D ++P SG +S+ Q + Y + + D P L + + + N ++ + ++ + N E EES
Sbjct: 2128 PRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANE--TAIMENVAINTVVIAVKAVDNDEGRNGYIDY-LMKEARDEDMG---QSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRY---SIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYL----ARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLF---RIN---ASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYT---------ISGRDQH-----YFDINT-------------KTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRP----GKMITKVSATSPKKGLVGKIRYAI-AGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQ--LIYNAEVLEEES 2824 HSP 3 Score: 195.667 bits (496), Expect = 5.542e-50 Identity = 200/735 (27.21%), Postives = 315/735 (42.86%), Query Frame = 3
Query: 399 FEINPLNGVITIER--RIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNG-ISYYSISPEITEFELSYIINTNT-MMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCT----------------------VIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANE--EFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTS-GSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI-FGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPK-SIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKL-IIRESGLDREVTTKYEIVIEATDRGNPPK---STKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISL 2498
F I P+ GV+ ++R R + +L H+ L T S + L + + D+ND++P + T E +++ A D D G NG ISY II NT M+ L ++ LDRE+ D Y V+ D G PS + + V++ V DENDN+P F + + S+ EN ++T V +L A+D D N ++ + +SS T+ F+I++ +G+I D E +S EA+ RGS V + + D+NDN+PE P T I+E + G + QD D NG V L NE +F+L+ + ++S + DRE + +V D +S S+++ V D ND AP F++ S V E GT L A+D D+G+N+ + +SI G F I+ + G ++L LD E + S A+D G P +T V+V D NDN P P +I + E P+V V D D GLN + + K++ + P + F T++ G + +RE +DRE + + + ATDR P + ST+ ++ + V D+ND P F+ + + K S T + Q+ A D D N + Y S Q +LF + +G I+
Sbjct: 992 FRIGPVTGVLYLQRPIRAEPGSLIHV------------ELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYE-------------IIEGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQD-----FTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVT----ISEGASEGTHITHVFTQDADEGLNGDVYYSLAK-GNEAGQFNLD------SATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAIS--------KQEPQLPQGRHFGINTET-----------GVIHTLRE--IDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQ--ELFKLQRNTGIITF 1662 HSP 4 Score: 176.792 bits (447), Expect = 3.961e-44 Identity = 178/698 (25.50%), Postives = 305/698 (43.70%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYI----ISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWE-LDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLV-QVNVTDAD-EGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
L I V D+NDN P + E G+ ALD D G N + +Y+IS + + INT T + S K +LK K D Y +++A D G S + ++ V + +F Y+ +++E+++ + ++ A + GKI Y I+ + + ++ NSG + V + LDYE + +EA D S + +N+ D NDN+P + + NA++ E E+P +L+AV D+DS +NG V L+ + F + T +I T DRE+ + D+G P T + SV + + D ND P F+ + + +V E+ + G+++ + ++D D G NA SYS + F I G + + LDRE + A+D + + IT+ ++D NDN P S Y + + LV Q+ TD D +G NS +L + I + ++F F +S + P+ Y + + ATD G PP ++ ++ IN++D ++ PKF + + V G I ++ A D+ + +E++YS + N ++ +F + G I+L + IQ Y L+V D G+P D R+ I++ N D+
Sbjct: 2582 LTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHY---FDINTKTGVVSTKLELKTKTKSHDDL----TYTIVISAMDQGEQSLSSKAELTVILRPPE----LFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLR---VDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVM----EQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEI-------TESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFT-RLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGAWRAETP---ITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSI----DPATGEVFSKKAVRFKHSQYVRSPE---------------NMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKF---EQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSS-IFSVGRHDGWITLVKPIQVPPNT-RYELVVRATDRGVPPQSDETRVVIVVTGENMDT 3226 HSP 5 Score: 176.022 bits (445), Expect = 7.638e-44 Identity = 191/800 (23.88%), Postives = 343/800 (42.88%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDD-----FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITE-FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPS-FNGSIKVIVAVTDENDNSPVFEKAVYI---------ISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVR--------WELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRD----LNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE--PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGS------VSVGVEDINDEAPHFS---EKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVL-ENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQ-----TNDLFL--MNP----------ESGKISLQQTIQESHKVCCYVLI-VVVKDNGIPRLEDTARLRIIIESIN 2621
+F ++PL G+I +DR+ + ++L+I + D F++ + VI + D ND +P +SQ E E + +L A D+D GTNG ++++P + + L + ++ T + + L DREK+ +YE V A D G P+ + + V + V D NDN P F YI I + + ++ ++ + A D D N IEY++ S + LF +++ SG I +R W+ Y+ L+V A D G R V I ++ L + + + + N P + V + V+ + NGK H+E I + R++ T +I+T + DRE+++ I+ + S V++ + D+ND AP F+ E + E+ G ++ D+D G+N+ +SYS+ + F I + G ++L+ + E +H A D+G P S +++V++ D+ND+ P + Y L E + + TD D G N ++ ++ + + +F + PDG L +R + LDRE Y + + D G P +S+ + I+V+D ND P+F + S T + + T + ++ A+D D G+N+EL ++ S Q T + F+ + P + + S + Y+L+ V DNGIPRL+D ++++I+ +N
Sbjct: 541 WFSMDPLTGLIVTTGPLDREI--------------RDTVELSISARDGGPNPKFAYTQLKVI-ILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPL--------DREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGE----GLFQLDARSGAISLRGDAPASMHWKPHYK------LLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVK----STNGKANSHIEYDIIQGDRAQNFRID---TRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNG------------------------RISYEIIEGNTERMFGVFPDGYLFVR-APLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQF---TNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVN 1272 HSP 6 Score: 169.474 bits (428), Expect = 7.410e-42 Identity = 190/702 (27.07%), Postives = 306/702 (43.59%), Query Frame = 3
Query: 540 FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSIS---PEITEFELSYIINTNT-MMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPS---FNGSIKVIVAVTDENDNSPVF---EKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEAND--MGNLRRGSTCTV-IINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEF-----------SLERMNIPLTVMYKISTLKSFDRE---QKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKD 2561
S ++ + V D NDN P + +V Q EG + A D D G NG Y+IS P++ + + INT T ++++ +E +DRE ID + V A D PS + V V V D NDN+PVF A+ + + S+T V+Q+ A DADS NG + Y+I ++ P+ +LF ++ N+G I ++ L +++ D + + RR S + II S FE R + + ENE G + VT HL E F ++R+ + +ST DRE ++ +V + + G PR T+ V V V D ND P F + ++++V+ED++ G + T+ A D D + ++ + G D K F + GK+ L LDRE+ R +D Q + A T+ V D NDN P ++Y + + EN + Q+ DAD G N++ +VS+ ++N +FSL P ++ + LD E Y ++++A D G P ST +Y NVLD+ND P F S S+ + P T + + A D D G N +EYS + + ++ + + +G I ++ + H+ Y L V +D
Sbjct: 1469 LSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGR-HFGINTETGVIHTLRE---------IDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEI--VSGPQ--ELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFE-QRSKLSGSVYENEPIGTSILT-------------VTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALG-GQPR-TSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDT-LGSVTFLLMDGHDGK-FLLEPSTGKLILNDTLDRETKSKYELRIRVSDG---VQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSD------------------------WANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVP---IATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDS--NGTIRTRRNLDREHR-STYTLTVTARD 2105 HSP 7 Score: 167.162 bits (422), Expect = 3.962e-41 Identity = 201/758 (26.52%), Postives = 324/758 (42.74%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDN--LCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIV----LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEY--AKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCT---VIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT----------VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYI-FHVNEDVKPGTYLFTINA----TDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRES-VESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPD-GKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDT 2588
F ++ G +++ RR+DR++ + HL+ + D H + + I V D NDN+P ++Q+ E S G A D D G N +SIS + +I + +Y +K LD E I Y + A D G PS + ++ V V D+NDN P+F + + E + TP++ + A D DS +NGK+ Y IS +P+ + F I + +G IH E+D E+ T L V A D T V + + D+NDN+P ++ + K + ++ V +D DS+ NG VT + E F L+R +T V Y++ TLKS D +S+ + V P + GS S P F ++S + V E+ GT + T+ A + + + + + G+ ++F I+ G + +LDRE+ E A G + S + V V D ND+ P + ++Y N + D+ + T TL + TL + L D + F L P GKLI+ ++ LDRE +KYE+ I +D + T+ I V D ND P F + + + G + QI+A D D G+N++L Y S+ ND+F +NP++G ++L + + +V Y+LIV +DNG P L T
Sbjct: 1326 FNLDSATGQLSLGRRLDRESQEIHHLI---------------VVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAG-NRRDTFHIDSITGSLYLHKP---------LDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISK-QEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAP-VFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQL-TLKSTDEAVQSERRSSEVYITIITP--GSGGSES--------SVPQFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVY---NVSEDLQI-------------GHTISTLRAHDPDTLGS------VTFLLMD----GHDGKFLLEPSTGKLILNDT-LDRETKSKYELRIRVSDG---VQYTEAYATIQVSDTNDNPPLF---EDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSD-WANDVFSLNPQTGMLTLTARL-DYEEVQHYILIVQAQDNGQPSLSTT 2010 HSP 8 Score: 146.362 bits (368), Expect = 7.951e-35 Identity = 166/624 (26.60%), Postives = 271/624 (43.43%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALD-NDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE--FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQT--TSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGK-DAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNS 2417
I + D ++N P + Q E + + + G A D D GTN + Y + F LS I + + + L K + +YE +V A D G P + +V++ VT EN ++P F Y + V EN + ++ + A D D+ NG + Y IS + + FS++ +G I ++ +LDY+ L + D+G S + I + D+NDN P F + + I EN+ G V DKDS +N + P + F + + N IS+ SFD E++ T I NP + + ++ V V +N+ P F + + F V+E GT + + ATDKD G + + Y + G + K F I+ G +++ LDRE+ + T A + G + T VI+ + N P P+ I Y + P+ TKVT V + + +++ + ++ +SF + + G+ I S LDRE T+ Y +VI A D G PP++ ++I + DVND P F P G N + +GT+I +IA D D +N
Sbjct: 3112 INIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDY-----SLMTFNLSSIFSVG------RHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNE---RQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPP--VFNHKEY--HCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSN------GTISSAVSFDYEERRIYTLQIKA---KNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDP--PEFIKHYYTSTISEAAPV--------------GTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQT----GE-ISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFT-PEGLNG--YISENEPAGTSIMTLIASDPDLPRNG 3684 HSP 9 Score: 145.206 bits (365), Expect = 2.072e-34 Identity = 184/711 (25.88%), Postives = 310/711 (43.60%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEM-NGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTI-------SLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKD---SNEN--GKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGI--IYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF--KSNNQTNDLFLMNPESGKISLQQTI--QESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGD 2627
+++ + D NDN P +++ +E +EIG + D D G N + YS S N + + + LDRE+ D+Y V A DG ++ + + + D+NDN+P FE + Y S E QS V Q+ A D D + N I Y SL +P + +FSI+ +G + + + ++ + +L V A D G S C V INI D ++N P+ FE + + A + ++ G+ + DK +NE +T +L I FS+ R + +T++ I + E + T D G P Q+ V + V N + P FS SY V E+ G+ + T+ ATD D G N +L YSI G + + FS+++ G + ++ LD + ++ H D GY S A +T+I+ D+NDN P F K + Y+ EN + Q + D D N+ + P + F + + ++ S + D E Y + I+A NP S + +Y++VL VN+ P+F+ P V + GT + + A D+D G++ + Y SN++ F ++ +G I + + + + ++V VL V+ K+ G R DT ++II +G+
Sbjct: 2899 VLLHLLDKNDNPPKFTR-LFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSE-----------NPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDG---AWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISY---SLQQP--SPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPK--FEQAEYL--APLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSI----FSVGRHDGWITLVKPIQVPPNTRYELVVRAT------DRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSG-----------PDRHFF--IMNQSNGTISSAV----------SFDYEERRIYTLQIKAK---NPDSSMESYANLYVHVLGVNEFYPQFLQPV---FHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKG---FRIDTNTGLIYVARHLDRETQNRV---VLTVMAKNYGSIRGNDTDEAQVIISIQDGN 3540 HSP 10 Score: 141.739 bits (356), Expect = 2.338e-33 Identity = 206/777 (26.51%), Postives = 329/777 (42.34%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSP-FWSQNELVTQFSEGSEIGDSKSLTV--ALDNDFGTNGISYYSISPEITE-FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNS-----PVFEKAVYII-SVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLT----KPEYAKLFSIESNSGYIHVRWELDYETYT-TISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNS--ETKVTL--------VSETATTLIKR------KDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSN-----NQTNDL-FLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
+F IN GVI R IDR+++ T Q S+ S ++ + V+DINDN+P F S N + + G S ++ A D D +NG+ Y I E F+L NT + ++ Q ++++ +Y+ + + D S S +V + + P FE+ + SV EN T ++ + A A +E IEY ++++T + + +LF I++ G + ELD E + V A +G R S V + + D ND+ P+ P F N ++E+ G ++ D D+ G VT L + +F LE P T K+ + DRE KSK I D Q T ++ V D ND P F + Y F + E+ + G + I A D D G NA LSY + A +FS+N G + L LD E V+ +A D+G P +T + V D+NDN P F P S V EN +V V+ D D G N E +T + T +R + Y + RD F++ FS L + +L ++ + T+ E + + S+ + I + DVND P FI +N T ++ ++ IA + A+D DEG+N ++Y K Q++ L F +NP G++ + + + Y+L + +D G P ++L I I
Sbjct: 1540 HFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQ-------PSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQELFKLQR--NTGIITFTPGPQF---------KQEV-RYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLASAE----IEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTP--FVYN--VSEDLQIGHTISTLRAHDPDT--LGSVTFLLMDGHDGKFLLE----PST--GKLILNDTLDRETKSKYELRIRVSDG---VQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFAS--FSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQR---LSSTVKVTILIKDVNDEVPVFI---SANETAIMENVAINTVVIA-VKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELR-SSYLLNITARDRGEPPQSTESQLLIRI 2268 HSP 11 Score: 138.272 bits (347), Expect = 2.401e-32 Identity = 151/532 (28.38%), Postives = 230/532 (43.23%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIK--SDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNP--SFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGST--CTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKI-------STLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGIN-ALLSYS-IFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYV 1949
F ++ G I I++++D D + + +L++T++ S + +L I + D+NDN P ++ E E +G A D D N I +Y+ P + +I+N + S+ D E+ Y + A NP S + V V N+ P F + V+ V+E T V ++A D DS +G++ Y L K F I++N+G I+V LD ET + L V A + G++R T VII+I+D ND PE F +T + I+E G V DKD N +FS +N L +KI ST DRE+ S I D G P QT S +V + +ED+ND P F+ + +++E+ GT + T+ A+D D N +Y I GK S+++ G V T DRE L DSG PKQ S +T+ V D NDN P +S+++ V
Sbjct: 3277 FSVDERTGGIVIQQQLDYDLI------------QEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHF-FIMNQSNGTISSA--------VSFDYEERRIYTLQIKA---KNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYL---LVGSSNDKGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPE--FIKHYYT--STISEAAPVGTKVTTVKAIDKDVRTQ-----------NNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDN-PSTTRSLHIAV 3764 HSP 12 Score: 128.257 bits (321), Expect = 3.142e-29 Identity = 175/757 (23.12%), Postives = 315/757 (41.61%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDND-FGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAK---ITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANE--EFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF--GKDAKIFSINKLDGKVFLETDLDRES--VESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATD----RGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDED-EGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
F I P +G IT+ +DR+ + ++ L + + SD + + I ++D NDN+P + + F E + +A D D G N + YS+ F I ++S K + E + Y V A D G P V + + D ++N P FE+A Y+ + ++ ++++ A D +++Y SL + +FS+ + G+I + + T L+V A D G + V+I + N ++P RF+ N+ + ENE G + D D+ NG + + NE +FS++ + + ++ +D Q+ + +I D G ++ +++ + D+ND P F+ K Y ++ E+ GT++F +A DKD NA++ Y+ G D F +N+ +G + D E + +L + DS S AN+ V V +N+ +P FL + V E + V TD D G + LV + K FR T + LI LDRE + + + A + RGN + + + I++ D ND P+FI +++ + P GT + + AID+D +N++ YS + N F ++ ++G+IS + + + Y L++ D G+P +A + I +E +N
Sbjct: 2959 FRIEPQSGNITVAGHLDRE------------QQDEYILKV-VASDGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFS---IDPATGEVFSKKAVRFKHSQYVRSPENM--YALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDY---SLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTP-------RFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISG-GNERQDFSVDERTGGIVIQQQL----DYDLIQEYHL--NITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDS---SMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSN------------DKGFRIDTNT------------GLIYVARHLDRETQNRVVLTVMAKNYGSIRGN--DTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAP---VGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQS-FKIDVQTGEISTASRL-DREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVN 3645 HSP 13 Score: 93.9745 bits (232), Expect = 7.737e-19 Identity = 99/374 (26.47%), Postives = 141/374 (37.70%), Query Frame = 3
Query: 1569 VSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALL-SYSIFGKDA----KIFSINKLDGK---VFLET--DLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVL-ENHTADVPLVQVNVTDADEGLNS---------ETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKF---IFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
V + V D+ND +P F E S +E GT L ATD D G N + Y I + ++ + G + LET +LDRES S A D G P + + V + D+NDN P S Y L E P+V V +D D G NS E + T+ ET + P Q + + S + +F++ A D G+P + + + +N+LD ND P FP G V V+GT +A + D D G N S N+ L I + + ++ Y L VV D G P TA L I + +N
Sbjct: 142 VRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKS-SASQKSCVFTVF-------------------------ARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGK-VATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVN 488
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 243.432 bits (620), Expect = 5.511e-65 Identity = 195/657 (29.68%), Postives = 311/657 (47.34%), Query Frame = 3
Query: 552 IVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI-SPEITE-FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDS-NENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF---GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRT---VSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKI 2492
I +++ VKD NDN+P + Q + +F E + ++L A D D Y+I S + + F LS + ++Y + + + LDRE Y ++ A DGG P G + V + + D NDN P+F ++ Y +V EN T V+Q+ A D D++ NG +EY I+ + + ++F I+ +G I++ LD+ET L+V A D G +T V I + D+NDN P I + KI+E+ PG+ VA SV D DS E V L + F+L + +Y + DRE S T +V D+G P S S+ + + D+ND P F + Y +V E PGT + + A D+DEG+N+ L+YS+ A+ F I+ G + + +D E+ T A D G P STA + V + D+NDN P +S Y + V EN +++V+ +D D G+N+ Y I + F+ +T+ F + I LD E + YE + ATDRG ST +I + + DVND +P F +P +++ P+ S T I ++A D D G ++ Y + N+ +F ++ +G+I
Sbjct: 158 IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQ-----ISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINR-RQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNG-GDGHFALTTRD---NSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVN-----------------YTIGEGFKHLTE------FEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVF-YPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAG-IFRIDRSTGEI 777 HSP 2 Score: 239.195 bits (609), Expect = 1.177e-63 Identity = 224/768 (29.17%), Postives = 352/768 (45.83%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQI---------SSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSE-KSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAK---IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRK-DEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDR--GNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF--------KSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKD---NGIPRLED--TARLRII 2606
YF I +G I I + +D + K N+ T+ + H V IEV+D+NDN+P + + + E +E+G A D D G++G YS+ E + + + ++ S LD E ++ IV A DGG PS + ++ ++V V D NDN PVFEK Y ++V+E+ N +IQ+ A D D+ N +I Y+I +S++ + ++ F I NSG+I++R LD ET L V A D G + VI+ + D NDN P+ F+ S++ +I EN G +V V + D D EN + L PI N F + P+T +IST + DRE + + D+G P ++ V + V D+ND AP ++ + + V E+ PGT + + A D+D G NA ++YSI G+D+ +FSI+ G + LD E A+D G P + + + V V D+NDN P F S+ V E D L V + S + + ++ ++ ++ + +TK + F + ++ LDREV +++ + I A D N P+S+ + I V DVND P++ ++V T GT I A D D G N +L+Y +S Q LF M+ +G +SLQ + + V Y+LIV D N RL+ T RLRI+
Sbjct: 874 YFSIETNSGNIRIAKPLDHE----------AKSQVLLNIQATLGEPPVYGHTQV-NIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQH----------LDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPK--FQKSKY--EFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPI-NSSFQVH----PVT--GEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVRE----DAALGHV--------VGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEW---PQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPL-DFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRIL 1593 HSP 3 Score: 201.83 bits (512), Expect = 7.434e-52 Identity = 201/723 (27.80%), Postives = 311/723 (43.02%), Query Frame = 3
Query: 540 FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLT-----VALDNDFGTNGISYYSI--SPEITEFELSY----IINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF--GKDAKIFSINKLD-----------GKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQ-VNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLP-DGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTN--DLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
S ++ +++ D+NDN P + E E + S T VA D D+G G Y I E F + I M S + Q + ++A DGGN N V +++ D P+FEKA Y V E++ T V + A D + Y I S Y FSIE+NSG I + LD+E + + L ++A +G V I + D+NDN+PE FE S + E+ G + DKDS +G+VT L + + F+++ + L + + D E + T + D G P +T+ ++ V V+D+ND P F + Y +V+E + +NA+D D G NA ++Y I G D SI+ D G ++L LDRE+ + T A D+G P + + V V D NDN P KS Y + +E + +V V +D D G N+ + +L+ PI NS F + P G++ RE LDRE+ Y++V+EA D+G P +S + + I+V DVND P+ P V V+ GT + ++ A+D D G+N+ + YS ++ LF ++P SG I + + + Y L V D G P E LR+ + +N
Sbjct: 695 LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPM--------------HMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGY---FSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPE--FEASMV--RISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS------QHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLL--------------PI------------NSSFQVHPVTGEISTREP-LDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADP--QEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEER-SIYRLGVAASDGGNPPRETVRMLRVEVLDLN 1359 HSP 4 Score: 181.03 bits (458), Expect = 2.019e-45 Identity = 184/725 (25.38%), Postives = 306/725 (42.21%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFT--NNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKS---NNQTNDL--------FLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKENKMKDNVEYSNEES 2687
+ + + D+NDN P + Q+ E ++ G S +A D D G N YS++ + I+ T + + + + D E + V A DGG P + + V+V + D NDN P+F+++ Y +SV EN ++++ A D D +N + Y I K + F + S SG I + ELD+E ++ V A D G L +T + + + D+NDN P Y + + + K + + +VAV + D D G+V+ + +A E + R++ ++ + R Q + +I D GN R V + + D P F + Y ++V ED+ GT + ++ A D + + YSI+ D FSI G + + LD E+ + +A G P + + V+D+NDN P F + + V E+ PL + D D G + + +LV E+ LF++ +I LD E + ++ +++ ATD G P ST I ++V DVND P F +V V I Q+ A D D G N+ + Y +N TN + F + P SG I L+ + + Y L V+ DNG P A+ R+I+ ++ + K K K E+ EE+
Sbjct: 490 IFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHI--------DCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFK--HLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGL--STTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVAT-DPDYGNFGQVSYRI--VAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHML-NISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESG------------------------KGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF---EKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRD-RYQLTVLATDNGTPAAH--AKTRVIVRVLDANDNDPKFQKSK--YEFRIEEN 1165 HSP 5 Score: 176.792 bits (447), Expect = 3.842e-44 Identity = 186/690 (26.96%), Postives = 306/690 (44.35%), Query Frame = 3
Query: 552 IVLVIEVKDINDNSPFW-----SQNELVTQF-SEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPS-FNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIV---EAN--------------------DMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE--PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSG-SVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSG-YPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVP---LVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKV--KPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQ 2504
+ + + + D ND++P + S + + F S+ + IG+ + VA+D D G NG Y I+ E + IN+ T + E +K + D EK ++ I+ A D G P S+ + + V ++N P F +AVY ++ EN+ S + V+Q+ A N + Y+I + + LF ++ G I R + D E+ + L V +AN D N + T+ I + D+NDNSPE F P + EN PG + V + D D N + + + N+ FS++ + L+ + DREQ S+ T I D G P+ ++++ VED ND AP F Y V ED GT + I+A D D G+NA L YS+ + F+I+ G + LDRE S +F A D G Y + +T + + V DINDN P + Y Y+ + P L++V DAD G N+E +L +E + K F + P + L E + + A D+GNPP+S+ G+I + + + P F N T +V K + SGT + Q++A+ D G+ ++++SF + N+ + + ++ SG+I + +
Sbjct: 1586 VTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITG--GNGEGRFRINSQTGII---ELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAND---LFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPE--FRPGS-CYGLSVPENSEPGVIHTVVA-SDLDEGPNADLIYSITGGNLGNK-FSIDSSSGELSA-------RPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFER--YPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAK----------------------FRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRF---QNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGAGNE-DGILSLDSLSGEIRVNK 2226 HSP 6 Score: 155.606 bits (392), Expect = 1.215e-37 Identity = 169/613 (27.57%), Postives = 258/613 (42.09%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWE----LDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPH----FSEKSYIFHVNEDVKPGTYLFTINATDKDEGIN-ALLSYSIFGKDAKIFSINKLDGKVFL---ETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
DRE Y + G N I+V+V V DENDN+P F + I EN L A D D E Y I S + +L S G +++ + LD ET SL++EA D G TV I I+D+NDN P F SR+ A + EN G V D D++ENG V + +++ + R++ P T I+ K+ D E K +V D G T+ VS+ V D+ND P F ++E +PG ++ I+ D D A ++ ++ G D F++ D ++L LDRE V + + A D G P ++ +I + + D+NDN P + +Y V+E ++QV D DEGLNS +L +ET T F + P LI S +D E ++ + A D G PP S+ + + + DVND +P F S V V G I ++ A D D G N+ + Y+ + F + SG+I + + + + Y V+ D G L TA +++ + +N
Sbjct: 139 DRETRASYSLVAIPLSGRN------IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQSRYF--ATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRID-PRTGAIYIN--KALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGH-FALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSL-AETPET---------------------HAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIF---DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGEL-DFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDVN 709 HSP 7 Score: 144.05 bits (362), Expect = 3.762e-34 Identity = 205/800 (25.62%), Postives = 329/800 (41.12%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHI----IVLVIEVKDINDNSP-FWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNG-ISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAID--ADSEMNG--------KIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDM--GNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE---PIANEE----FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGN---PRQTTSGSVSVGVEDINDEAPHFSE------KSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDL-----DRESVESLHFTTRAADSGYPK-QLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPR-LEDTARLRIIIESINGDSILSKENKMKDNVE 2669
F+++P+ G I+ +DR+ L L DL +++ D + + + + I V D+NDN+P E V E G A+D D G N I+Y + ++ + I+ + + + LD E+ Y V A DGGNP + V V D NDN P F + + V E+ V + I+ AD N ++ Y ++ LTK F I+ +SG + V LD E + L + A D N + S TV I + D+NDN+PE +P + +++E G ++ F+ D D+ NG + L P NE SL RM+ ++ +S D E + + D+ + R TS +V + + D ND APHF K+ +++ + G + I A D+D G N L+Y I G + + F IN G + L L D E + A D G P+ + S+ N+ +IV+ ++N P +++Y +LEN + ++QV N+ + + A L + I R S + + L + R+S L K D N IYI V DVND P+ F GS + V P I ++A D DEG N++L YS N N F ++ SG++S + +E H Y L + D G P+ + + I +E N ++ K +K +V+
Sbjct: 1199 FQVHPVTGEISTREPLDRE-LREL-------------YDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTR--------VVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPI----DLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMD---SLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITT-RGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPE--FRPGSCYGLSV-PENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNK-FSIDSSSGELSARPLDREQHSR--YTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQ 1962 HSP 8 Score: 142.51 bits (358), Expect = 1.086e-33 Identity = 188/753 (24.97%), Postives = 319/753 (42.36%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSF-NGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPG-KLVAVFSVQDKD-----------SNENGKVTCHLEPIANE-------EFSLERMNIPL---------------------------TVMYKISTLKSF--DREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSIN-KLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYP--IQKLFRDVTKSFSN-SLFSL-LPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDED-----------EGKNSELEYSFKSNNQTNDLFLMNPESGKIS-----LQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRI 2603
+ I V+D NDN+P + ++ E + +G S A+D D G N YS++ E T+++ + + + K LDRE Y F+V A DGG + ++ V + V D NDN P+FE+ YI V +Q +++++A+DAD N +I Y +++ AK F I ++G + L E+ + L V A D GN + S + + I + +P + F+ T + EN G +L+ V +++ NE+G ++ L+ ++ E +R + P T + T SF Q +++ +V P + + + +ED ND +P FS+K ++ V+E GT++ ++A D D G NA L Y I G F I G V LDRE + A D G P+ TA I V + D+NDN P P P V V++A +E + S +A + D YP +L + T N S+F+L GKL+++ LD E+ +YE+ + A+D + ++ ++ + V D ND P F+ + + P + I++ +++D D EG NS++ Y + + F ++P +G +S LQ + S Y + ++ KD G P L+ + LR+
Sbjct: 1938 ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANE-TQWQFAIDGQSGLITTVGK----------LDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAK-FRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNE--TYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILS--LDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFP---------------PNNLVTVSEA-----TELGAVITSISANDV----DTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRR-LDYELQQEYELDVIASDAAHEART---VLTVRVNDENDNAPVFL-AQQPPAYFAILPAI---SEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG---FSVHPSNGVVSVNMSRLQPAVSSSGD---YFVRIIAKDAGKPALKSSTLLRV 2636 HSP 9 Score: 115.931 bits (289), Expect = 1.689e-25 Identity = 160/673 (23.77%), Postives = 274/673 (40.71%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI------SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFE--PSRFTNNAKITE-NEAPGKLVAVFSVQDKDSNE---NGKVTCHLEPIANEEFSLERMNIPLTV-MYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYP------KQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADV--PLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSL-LPDGKLIIRESGLDREVTTK-YEIVIEATDRGNP-PKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF---KSNNQTNDLFLMNPESGKIS 2495
LVIE++D NDNSP +SQ + V SEG+ G + A D+D G+N Y I + + E S I+ TN ++ DRE D Y+ + A D G P G+ + V + D NDN P F +++V+E + + + A D D+ S E +F+++ SG + ++ LDYE L V A+D + R + + + D NDN+P + P+ F I+E +E+ + +V D++ N KV +EP A E FS+ N ++V M ++ S I+ D G P +S + V D F + Y ++E G+ + + D+ + I G + F + + V ++ LDRE + + P S ++ + + D NDNFP +S + A + + Q+ DAD+ + P ++ D+T +F++ L G L + LD + K YE++I A D + P + + + D ND +PKF + + +P G+++ + A D D+G +L YS S+ + +F ++ ESG ++
Sbjct: 2308 LVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVL---------------DREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPN-NLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR---TVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEP-AQEGFSVHPSNGVVSVNMSRLQPAVS----SSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAI-----IAGNEESAFELLQSKAIVLVKP-LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQ----------------------ENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNR-LDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEP---VGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVT 2924 HSP 10 Score: 95.5153 bits (236), Expect = 2.916e-19 Identity = 143/586 (24.40%), Postives = 237/586 (40.44%), Query Frame = 3
Query: 879 PSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIE-SNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMY--KISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAP---------HFSEKSYIFHVNEDVKPGTYLFTINATDKD-EGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESL-HFTTR--AADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPP------KSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGK--NSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDN 2564
P ++++ + DENDNSP F + ++ +V+E T V Q+ A D+D+ N ++ Y I + F IE + SG + LD E L + A D G + T T+ + I D+NDN P F N +T +EA + S+ D + +T L A +E M+I Y K+ + D E + + ++ D + +T ++V V D ND AP +F+ I ++E + L T+NATD D EG N+ + Y I + FS++ +G V + + +V S + R A D+G P S+ T++ NDN + + + PL V + + L+ + +E S F LL K I+ LDRE Y++ + + PP S+ + I +LD ND P IF + ++ +IAQ+ AID D+ NSE+ Y S N + +F ++ +G + + + Y LI+ D+
Sbjct: 2300 PFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHI---VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPT-------FPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLG--AESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTV---LTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY-IIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSS---TLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNE--------------------------ESAFELL-QSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFP--IFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEH-MFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDS 2836 HSP 11 Score: 61.6178 bits (148), Expect = 5.435e-9 Identity = 69/286 (24.13%), Postives = 122/286 (42.66%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQN-ELVTQFSEGSEIGDSKSLTVALDNDFGT--NGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVI-VAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL 1400
++I + D NDN P + ++ + + SE + + S + A+D D N Y I+ E + + T + +N+ K YE I+ A D + S++ + + DENDN P F Y+ + EN + V + A D D G++ Y I E + K+F ++S SG + + DYE + + A+DMG + ++ V + I ++ +P+ RF A + + G +V + D DS +G+V L
Sbjct: 2738 VIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAK---------SYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGG--KKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQ--GYVVGQVTATDSDSGPDGRVVYQL 3010 HSP 12 Score: 52.7582 bits (125), Expect = 2.464e-6 Identity = 58/215 (26.98%), Postives = 96/215 (44.65%), Query Frame = 3
Query: 543 SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNP--SFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWE--LDYETYTTISL 1175
S + + I V DINDN P + + + Q + G + ALD D G N YS++ E + + IN +T S + L K L E V A D GNP S G I++++ + F+ Y + + EN S T ++Q+ A+ +D K+++ + + + S++S SG I V LDY+ ++T S+
Sbjct: 2038 SATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLE--------VVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQ-KVQFSFGAGNED---GILSLDSLSGEIRVNKPHLLDYDRFSTPSM 2240
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 243.432 bits (620), Expect = 5.511e-65 Identity = 195/657 (29.68%), Postives = 311/657 (47.34%), Query Frame = 3
Query: 552 IVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI-SPEITE-FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDS-NENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF---GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRT---VSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKI 2492
I +++ VKD NDN+P + Q + +F E + ++L A D D Y+I S + + F LS + ++Y + + + LDRE Y ++ A DGG P G + V + + D NDN P+F ++ Y +V EN T V+Q+ A D D++ NG +EY I+ + + ++F I+ +G I++ LD+ET L+V A D G +T V I + D+NDN P I + KI+E+ PG+ VA SV D DS E V L + F+L + +Y + DRE S T +V D+G P S S+ + + D+ND P F + Y +V E PGT + + A D+DEG+N+ L+YS+ A+ F I+ G + + +D E+ T A D G P STA + V + D+NDN P +S Y + V EN +++V+ +D D G+N+ Y I + F+ +T+ F + I LD E + YE + ATDRG ST +I + + DVND +P F +P +++ P+ S T I ++A D D G ++ Y + N+ +F ++ +G+I
Sbjct: 158 IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQ-----ISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINR-RQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNG-GDGHFALTTRD---NSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVN-----------------YTIGEGFKHLTE------FEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVF-YPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAG-IFRIDRSTGEI 777 HSP 2 Score: 239.195 bits (609), Expect = 1.177e-63 Identity = 224/768 (29.17%), Postives = 352/768 (45.83%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQI---------SSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSE-KSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAK---IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRK-DEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDR--GNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF--------KSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKD---NGIPRLED--TARLRII 2606
YF I +G I I + +D + K N+ T+ + H V IEV+D+NDN+P + + + E +E+G A D D G++G YS+ E + + + ++ S LD E ++ IV A DGG PS + ++ ++V V D NDN PVFEK Y ++V+E+ N +IQ+ A D D+ N +I Y+I +S++ + ++ F I NSG+I++R LD ET L V A D G + VI+ + D NDN P+ F+ S++ +I EN G +V V + D D EN + L PI N F + P+T +IST + DRE + + D+G P ++ V + V D+ND AP ++ + + V E+ PGT + + A D+D G NA ++YSI G+D+ +FSI+ G + LD E A+D G P + + + V V D+NDN P F S+ V E D L V + S + + ++ ++ ++ + +TK + F + ++ LDREV +++ + I A D N P+S+ + I V DVND P++ ++V T GT I A D D G N +L+Y +S Q LF M+ +G +SLQ + + V Y+LIV D N RL+ T RLRI+
Sbjct: 874 YFSIETNSGNIRIAKPLDHE----------AKSQVLLNIQATLGEPPVYGHTQV-NIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQH----------LDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPK--FQKSKY--EFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPI-NSSFQVH----PVT--GEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVRE----DAALGHV--------VGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEW---PQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPL-DFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRIL 1593 HSP 3 Score: 201.83 bits (512), Expect = 7.434e-52 Identity = 201/723 (27.80%), Postives = 311/723 (43.02%), Query Frame = 3
Query: 540 FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLT-----VALDNDFGTNGISYYSI--SPEITEFELSY----IINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF--GKDAKIFSINKLD-----------GKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQ-VNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLP-DGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTN--DLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
S ++ +++ D+NDN P + E E + S T VA D D+G G Y I E F + I M S + Q + ++A DGGN N V +++ D P+FEKA Y V E++ T V + A D + Y I S Y FSIE+NSG I + LD+E + + L ++A +G V I + D+NDN+PE FE S + E+ G + DKDS +G+VT L + + F+++ + L + + D E + T + D G P +T+ ++ V V+D+ND P F + Y +V+E + +NA+D D G NA ++Y I G D SI+ D G ++L LDRE+ + T A D+G P + + V V D NDN P KS Y + +E + +V V +D D G N+ + +L+ PI NS F + P G++ RE LDRE+ Y++V+EA D+G P +S + + I+V DVND P+ P V V+ GT + ++ A+D D G+N+ + YS ++ LF ++P SG I + + + Y L V D G P E LR+ + +N
Sbjct: 695 LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPM--------------HMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGY---FSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPE--FEASMV--RISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS------QHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLL--------------PI------------NSSFQVHPVTGEISTREP-LDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADP--QEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEER-SIYRLGVAASDGGNPPRETVRMLRVEVLDLN 1359 HSP 4 Score: 181.03 bits (458), Expect = 2.019e-45 Identity = 184/725 (25.38%), Postives = 306/725 (42.21%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFT--NNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKS---NNQTNDL--------FLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKENKMKDNVEYSNEES 2687
+ + + D+NDN P + Q+ E ++ G S +A D D G N YS++ + I+ T + + + + D E + V A DGG P + + V+V + D NDN P+F+++ Y +SV EN ++++ A D D +N + Y I K + F + S SG I + ELD+E ++ V A D G L +T + + + D+NDN P Y + + + K + + +VAV + D D G+V+ + +A E + R++ ++ + R Q + +I D GN R V + + D P F + Y ++V ED+ GT + ++ A D + + YSI+ D FSI G + + LD E+ + +A G P + + V+D+NDN P F + + V E+ PL + D D G + + +LV E+ LF++ +I LD E + ++ +++ ATD G P ST I ++V DVND P F +V V I Q+ A D D G N+ + Y +N TN + F + P SG I L+ + + Y L V+ DNG P A+ R+I+ ++ + K K K E+ EE+
Sbjct: 490 IFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHI--------DCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFK--HLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGL--STTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVAT-DPDYGNFGQVSYRI--VAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHML-NISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESG------------------------KGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF---EKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRD-RYQLTVLATDNGTPAAH--AKTRVIVRVLDANDNDPKFQKSK--YEFRIEEN 1165 HSP 5 Score: 176.792 bits (447), Expect = 3.842e-44 Identity = 186/690 (26.96%), Postives = 306/690 (44.35%), Query Frame = 3
Query: 552 IVLVIEVKDINDNSPFW-----SQNELVTQF-SEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPS-FNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIV---EAN--------------------DMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE--PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSG-SVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSG-YPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVP---LVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKV--KPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQ 2504
+ + + + D ND++P + S + + F S+ + IG+ + VA+D D G NG Y I+ E + IN+ T + E +K + D EK ++ I+ A D G P S+ + + V ++N P F +AVY ++ EN+ S + V+Q+ A N + Y+I + + LF ++ G I R + D E+ + L V +AN D N + T+ I + D+NDNSPE F P + EN PG + V + D D N + + + N+ FS++ + L+ + DREQ S+ T I D G P+ ++++ VED ND AP F Y V ED GT + I+A D D G+NA L YS+ + F+I+ G + LDRE S +F A D G Y + +T + + V DINDN P + Y Y+ + P L++V DAD G N+E +L +E + K F + P + L E + + A D+GNPP+S+ G+I + + + P F N T +V K + SGT + Q++A+ D G+ ++++SF + N+ + + ++ SG+I + +
Sbjct: 1586 VTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITG--GNGEGRFRINSQTGII---ELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAND---LFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPE--FRPGS-CYGLSVPENSEPGVIHTVVA-SDLDEGPNADLIYSITGGNLGNK-FSIDSSSGELSA-------RPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFER--YPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAK----------------------FRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRF---QNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGAGNE-DGILSLDSLSGEIRVNK 2226 HSP 6 Score: 155.606 bits (392), Expect = 1.215e-37 Identity = 169/613 (27.57%), Postives = 258/613 (42.09%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWE----LDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPH----FSEKSYIFHVNEDVKPGTYLFTINATDKDEGIN-ALLSYSIFGKDAKIFSINKLDGKVFL---ETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
DRE Y + G N I+V+V V DENDN+P F + I EN L A D D E Y I S + +L S G +++ + LD ET SL++EA D G TV I I+D+NDN P F SR+ A + EN G V D D++ENG V + +++ + R++ P T I+ K+ D E K +V D G T+ VS+ V D+ND P F ++E +PG ++ I+ D D A ++ ++ G D F++ D ++L LDRE V + + A D G P ++ +I + + D+NDN P + +Y V+E ++QV D DEGLNS +L +ET T F + P LI S +D E ++ + A D G PP S+ + + + DVND +P F S V V G I ++ A D D G N+ + Y+ + F + SG+I + + + + Y V+ D G L TA +++ + +N
Sbjct: 139 DRETRASYSLVAIPLSGRN------IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQSRYF--ATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRID-PRTGAIYIN--KALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGH-FALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSL-AETPET---------------------HAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIF---DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGEL-DFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDVN 709 HSP 7 Score: 144.05 bits (362), Expect = 3.762e-34 Identity = 205/800 (25.62%), Postives = 329/800 (41.12%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHI----IVLVIEVKDINDNSP-FWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNG-ISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAID--ADSEMNG--------KIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDM--GNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE---PIANEE----FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGN---PRQTTSGSVSVGVEDINDEAPHFSE------KSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDL-----DRESVESLHFTTRAADSGYPK-QLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPR-LEDTARLRIIIESINGDSILSKENKMKDNVE 2669
F+++P+ G I+ +DR+ L L DL +++ D + + + + I V D+NDN+P E V E G A+D D G N I+Y + ++ + I+ + + + LD E+ Y V A DGGNP + V V D NDN P F + + V E+ V + I+ AD N ++ Y ++ LTK F I+ +SG + V LD E + L + A D N + S TV I + D+NDN+PE +P + +++E G ++ F+ D D+ NG + L P NE SL RM+ ++ +S D E + + D+ + R TS +V + + D ND APHF K+ +++ + G + I A D+D G N L+Y I G + + F IN G + L L D E + A D G P+ + S+ N+ +IV+ ++N P +++Y +LEN + ++QV N+ + + A L + I R S + + L + R+S L K D N IYI V DVND P+ F GS + V P I ++A D DEG N++L YS N N F ++ SG++S + +E H Y L + D G P+ + + I +E N ++ K +K +V+
Sbjct: 1199 FQVHPVTGEISTREPLDRE-LREL-------------YDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTR--------VVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPI----DLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMD---SLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITT-RGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPE--FRPGSCYGLSV-PENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNK-FSIDSSSGELSARPLDREQHSR--YTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQ 1962 HSP 8 Score: 142.51 bits (358), Expect = 1.086e-33 Identity = 188/753 (24.97%), Postives = 319/753 (42.36%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSF-NGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPG-KLVAVFSVQDKD-----------SNENGKVTCHLEPIANE-------EFSLERMNIPL---------------------------TVMYKISTLKSF--DREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSIN-KLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYP--IQKLFRDVTKSFSN-SLFSL-LPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDED-----------EGKNSELEYSFKSNNQTNDLFLMNPESGKIS-----LQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRI 2603
+ I V+D NDN+P + ++ E + +G S A+D D G N YS++ E T+++ + + + K LDRE Y F+V A DGG + ++ V + V D NDN P+FE+ YI V +Q +++++A+DAD N +I Y +++ AK F I ++G + L E+ + L V A D GN + S + + I + +P + F+ T + EN G +L+ V +++ NE+G ++ L+ ++ E +R + P T + T SF Q +++ +V P + + + +ED ND +P FS+K ++ V+E GT++ ++A D D G NA L Y I G F I G V LDRE + A D G P+ TA I V + D+NDN P P P V V++A +E + S +A + D YP +L + T N S+F+L GKL+++ LD E+ +YE+ + A+D + ++ ++ + V D ND P F+ + + P + I++ +++D D EG NS++ Y + + F ++P +G +S LQ + S Y + ++ KD G P L+ + LR+
Sbjct: 1938 ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANE-TQWQFAIDGQSGLITTVGK----------LDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAK-FRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNE--TYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILS--LDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFP---------------PNNLVTVSEA-----TELGAVITSISANDV----DTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRR-LDYELQQEYELDVIASDAAHEART---VLTVRVNDENDNAPVFL-AQQPPAYFAILPAI---SEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG---FSVHPSNGVVSVNMSRLQPAVSSSGD---YFVRIIAKDAGKPALKSSTLLRV 2636 HSP 9 Score: 115.931 bits (289), Expect = 1.689e-25 Identity = 160/673 (23.77%), Postives = 274/673 (40.71%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI------SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFE--PSRFTNNAKITE-NEAPGKLVAVFSVQDKDSNE---NGKVTCHLEPIANEEFSLERMNIPLTV-MYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYP------KQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADV--PLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSL-LPDGKLIIRESGLDREVTTK-YEIVIEATDRGNP-PKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF---KSNNQTNDLFLMNPESGKIS 2495
LVIE++D NDNSP +SQ + V SEG+ G + A D+D G+N Y I + + E S I+ TN ++ DRE D Y+ + A D G P G+ + V + D NDN P F +++V+E + + + A D D+ S E +F+++ SG + ++ LDYE L V A+D + R + + + D NDN+P + P+ F I+E +E+ + +V D++ N KV +EP A E FS+ N ++V M ++ S I+ D G P +S + V D F + Y ++E G+ + + D+ + I G + F + + V ++ LDRE + + P S ++ + + D NDNFP +S + A + + Q+ DAD+ + P ++ D+T +F++ L G L + LD + K YE++I A D + P + + + D ND +PKF + + +P G+++ + A D D+G +L YS S+ + +F ++ ESG ++
Sbjct: 2308 LVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVL---------------DREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPN-NLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR---TVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEP-AQEGFSVHPSNGVVSVNMSRLQPAVS----SSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAI-----IAGNEESAFELLQSKAIVLVKP-LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQ----------------------ENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNR-LDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEP---VGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVT 2924 HSP 10 Score: 95.5153 bits (236), Expect = 2.916e-19 Identity = 143/586 (24.40%), Postives = 237/586 (40.44%), Query Frame = 3
Query: 879 PSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIE-SNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMY--KISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAP---------HFSEKSYIFHVNEDVKPGTYLFTINATDKD-EGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESL-HFTTR--AADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPP------KSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGK--NSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDN 2564
P ++++ + DENDNSP F + ++ +V+E T V Q+ A D+D+ N ++ Y I + F IE + SG + LD E L + A D G + T T+ + I D+NDN P F N +T +EA + S+ D + +T L A +E M+I Y K+ + D E + + ++ D + +T ++V V D ND AP +F+ I ++E + L T+NATD D EG N+ + Y I + FS++ +G V + + +V S + R A D+G P S+ T++ NDN + + + PL V + + L+ + +E S F LL K I+ LDRE Y++ + + PP S+ + I +LD ND P IF + ++ +IAQ+ AID D+ NSE+ Y S N + +F ++ +G + + + Y LI+ D+
Sbjct: 2300 PFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHI---VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPT-------FPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLG--AESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTV---LTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY-IIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSS---TLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNE--------------------------ESAFELL-QSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFP--IFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEH-MFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDS 2836 HSP 11 Score: 61.6178 bits (148), Expect = 5.435e-9 Identity = 69/286 (24.13%), Postives = 122/286 (42.66%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQN-ELVTQFSEGSEIGDSKSLTVALDNDFGT--NGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVI-VAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL 1400
++I + D NDN P + ++ + + SE + + S + A+D D N Y I+ E + + T + +N+ K YE I+ A D + S++ + + DENDN P F Y+ + EN + V + A D D G++ Y I E + K+F ++S SG + + DYE + + A+DMG + ++ V + I ++ +P+ RF A + + G +V + D DS +G+V L
Sbjct: 2738 VIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAK---------SYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGG--KKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQ--GYVVGQVTATDSDSGPDGRVVYQL 3010 HSP 12 Score: 52.7582 bits (125), Expect = 2.464e-6 Identity = 58/215 (26.98%), Postives = 96/215 (44.65%), Query Frame = 3
Query: 543 SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNP--SFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWE--LDYETYTTISL 1175
S + + I V DINDN P + + + Q + G + ALD D G N YS++ E + + IN +T S + L K L E V A D GNP S G I++++ + F+ Y + + EN S T ++Q+ A+ +D K+++ + + + S++S SG I V LDY+ ++T S+
Sbjct: 2038 SATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLE--------VVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQ-KVQFSFGAGNED---GILSLDSLSGEIRVNKPHLLDYDRFSTPSM 2240
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0339463) HSP 1 Score: 242.276 bits (617), Expect = 1.231e-64 Identity = 213/769 (27.70%), Postives = 337/769 (43.82%), Query Frame = 3
Query: 384 KSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDF---SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELS-------YIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFD---GGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNT---PVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYK---ISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI-FGKDAKIFSINKLDGK--VFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+S F+++ GV+T +DR+ + + + +DD F S L + V D ND+SP + + EG+ +G + A D D G N Y I L+ + I++ + + S + L DRE D Y +V A D + + V V V D+NDN P F + Y + V E+ T V ++A DAD N I Y I FSI+S SG + + LDYE+ + L++ A D G+ R +T +++N+ D NDN+P Y S+F + + EN G + D D N ++T S N PL V + + T+K DRE++ + +V D G P ++ S SV + V+D+ND P F+ K Y +V ED PGT + T+ ATD DE ++ L Y I G F+I +G+ + + LD + + T A DSG + TA + + + D N+ P + Y V E+ ++ V+ TD+D G+N++ +L E+ L S FS+ P I+ + LDRE T+ Y + + A D GNP S + I V DVND P F P S ++ + GT++ Q+ A D D G N ++Y + + F+++P SG I + + + V + L + D G P L T ++I +E +N
Sbjct: 402 RSQSLFKVDSRTGVVTTSASLDRELM-------------DVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSL--------DRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAI---IGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYT--SQFQES--VLENVPVGYNIIRVQAYDSDEGANAEIT--------YSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGL-------------------GSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILE---DALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGL-DRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVN 1107 HSP 2 Score: 201.83 bits (512), Expect = 6.393e-52 Identity = 210/728 (28.85%), Postives = 314/728 (43.13%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSL-TKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTV-----MYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVS---ETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTK-YEIVIEATDRGNPPKSTKGIIYINVLDVNDCKP------------KFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARL--RIIIESINGDSILSKENKMKD 2660
L++ V D NDN+P + ++ E +G + A D+D G N YSIS F L+ T + K LDRE+ ++ F V A DGG P + S V++ V D NDN P F Y +V E+ TPV + A D D + ++ Y+I++ T+ +A + ++ G I + LDY+ L V A D G R T TV INI D N+ +P FE + ++ A + E+ G V V S D D N ++T L NEE S+ + P I T DRE S + D GNP + + V +GV D+ND AP F Y + ED GT + + A+D D G+N + Y + +D + F I+ G + LDRESV H T A D G P ST + + ++D+ND+ P F I LYV EN + +++ D DEG+N+ +++ A +L+ R Q ++ + LD E T K +E+V+ A +PP I I V DVND P + FPSG I +I A D D + +L Y S N N L +N SG + L + Q + V + + V +GI + +L R+I E + +S+ + N+M +
Sbjct: 675 LLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQ----------TIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDED--SRLHYEITTGNTRGRFA--ITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAP--IFENAPYS--ASVFEDAPVGTTVLVVSATDSDVGVNAQITYSL----NEE-SINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQ-----------------------LLTMTELDYESTRKRFELVVRA---ASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGE---------------IGRIPAFDAD--VSDKLHYRILSGNNAN-LLRLNSSSGGLVL--SPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTE 1331 HSP 3 Score: 190.66 bits (483), Expect = 1.930e-48 Identity = 173/581 (29.78%), Postives = 255/581 (43.89%), Query Frame = 3
Query: 930 DNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPL----TVMYKISTLKSFDREQKSKVTAHIVCFDEGNP---RQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGT---YLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGK--ISLQQTI---QESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+ SP FE+A+Y+ SV E + V ++A D + + + Y + SL LF ++S +G + LD E V A D R T T+ +N+ D ND+SP FE +F A I E G V D+D +N ++ +E + + + +P+ + IST S DRE + D + R+T + SV V V D ND P FSE++Y V ED GT + I ATD D+G NA + Y+I G + + FSI+ + G V L LD ESV S RA D G P + +T + V V D NDN P F VLEN +++V D+DEG N+E ++ +R D +P+ ++ P + LDRE ++ + A D G PPKS + I V DVND P F + V GT + + A D DE +S L Y + N T F + ++G+ I++ Q++ QE ++L V D+G DTA + I I N
Sbjct: 354 NQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPT--FEAEQF--EASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSIS--------ERDDNFPL----------------AVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAF---NPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGN-TRGRFAITSQNGRGLITIAQSLDYKQEKR----FLLTVAATDSG--GRSDTATVHINITDAN 891 HSP 4 Score: 123.635 bits (309), Expect = 7.612e-28 Identity = 136/517 (26.31%), Postives = 213/517 (41.20%), Query Frame = 3
Query: 306 KWFPTDVNKLQDFGKPIYKFQFFNC-EKSSVYFEINPLN-------------GVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE---FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLD 1802
K++ +V + Q G P+ + E S +++EI N G+ITI + +D K+ + L + S + I + D N+ +P + E + +G + + A D+D G N YS++ E + + N + +V LDRE Y V A DGGNPS + + V + VTD NDN+P F+ +Y S+ E+ T VIQ+ A D D +NG+I+Y +S + + F I+ SG I LD E+ L A D G+ ST V I + D+ND+ P F + T + EN G +V D D N V H I ++ FSL + P + ++ T+ D E K +V +P + + V D+ND AP + IF+ D P + I A D D ++ L Y I G +A + +N G + L L+
Sbjct: 797 KYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDY------------KQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESING-----LGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGS--FVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPT--FASDKIT--LYVPENSPVGSVVGEIHAHDPDEGVNAVV--HYSIIGGDDSNAFSL--VTRPGSERAQLLTMTELDYESTRKRFELVV--RAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGEIGRIPAFDAD--VSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLN 1282
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0330601) HSP 1 Score: 242.276 bits (617), Expect = 1.280e-64 Identity = 213/769 (27.70%), Postives = 337/769 (43.82%), Query Frame = 3
Query: 384 KSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDF---SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELS-------YIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFD---GGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNT---PVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYK---ISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI-FGKDAKIFSINKLDGK--VFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+S F+++ GV+T +DR+ + + + +DD F S L + V D ND+SP + + EG+ +G + A D D G N Y I L+ + I++ + + S + L DRE D Y +V A D + + V V V D+NDN P F + Y + V E+ T V ++A DAD N I Y I FSI+S SG + + LDYE+ + L++ A D G+ R +T +++N+ D NDN+P Y S+F + + EN G + D D N ++T S N PL V + + T+K DRE++ + +V D G P ++ S SV + V+D+ND P F+ K Y +V ED PGT + T+ ATD DE ++ L Y I G F+I +G+ + + LD + + T A DSG + TA + + + D N+ P + Y V E+ ++ V+ TD+D G+N++ +L E+ L S FS+ P I+ + LDRE T+ Y + + A D GNP S + I V DVND P F P S ++ + GT++ Q+ A D D G N ++Y + + F+++P SG I + + + V + L + D G P L T ++I +E +N
Sbjct: 402 RSQSLFKVDSRTGVVTTSASLDRELM-------------DVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSL--------DRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAI---IGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYT--SQFQES--VLENVPVGYNIIRVQAYDSDEGANAEIT--------YSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGL-------------------GSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILE---DALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGL-DRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVN 1107 HSP 2 Score: 201.83 bits (512), Expect = 7.365e-52 Identity = 210/728 (28.85%), Postives = 314/728 (43.13%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSL-TKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTV-----MYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVS---ETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTK-YEIVIEATDRGNPPKSTKGIIYINVLDVNDCKP------------KFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARL--RIIIESINGDSILSKENKMKD 2660
L++ V D NDN+P + ++ E +G + A D+D G N YSIS F L+ T + K LDRE+ ++ F V A DGG P + S V++ V D NDN P F Y +V E+ TPV + A D D + ++ Y+I++ T+ +A + ++ G I + LDY+ L V A D G R T TV INI D N+ +P FE + ++ A + E+ G V V S D D N ++T L NEE S+ + P I T DRE S + D GNP + + V +GV D+ND AP F Y + ED GT + + A+D D G+N + Y + +D + F I+ G + LDRESV H T A D G P ST + + ++D+ND+ P F I LYV EN + +++ D DEG+N+ +++ A +L+ R Q ++ + LD E T K +E+V+ A +PP I I V DVND P + FPSG I +I A D D + +L Y S N N L +N SG + L + Q + V + + V +GI + +L R+I E + +S+ + N+M +
Sbjct: 675 LLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQ----------TIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDED--SRLHYEITTGNTRGRFA--ITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAP--IFENAPYS--ASVFEDAPVGTTVLVVSATDSDVGVNAQITYSL----NEE-SINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQ-----------------------LLTMTELDYESTRKRFELVVRA---ASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGE---------------IGRIPAFDAD--VSDKLHYRILSGNNAN-LLRLNSSSGGLVL--SPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTE 1331 HSP 3 Score: 190.66 bits (483), Expect = 2.165e-48 Identity = 173/581 (29.78%), Postives = 255/581 (43.89%), Query Frame = 3
Query: 930 DNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPL----TVMYKISTLKSFDREQKSKVTAHIVCFDEGNP---RQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGT---YLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGK--ISLQQTI---QESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+ SP FE+A+Y+ SV E + V ++A D + + + Y + SL LF ++S +G + LD E V A D R T T+ +N+ D ND+SP FE +F A I E G V D+D +N ++ +E + + + +P+ + IST S DRE + D + R+T + SV V V D ND P FSE++Y V ED GT + I ATD D+G NA + Y+I G + + FSI+ + G V L LD ESV S RA D G P + +T + V V D NDN P F VLEN +++V D+DEG N+E ++ +R D +P+ ++ P + LDRE ++ + A D G PPKS + I V DVND P F + V GT + + A D DE +S L Y + N T F + ++G+ I++ Q++ QE ++L V D+G DTA + I I N
Sbjct: 354 NQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPT--FEAEQF--EASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSIS--------ERDDNFPL----------------AVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAF---NPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGN-TRGRFAITSQNGRGLITIAQSLDYKQEKR----FLLTVAATDSG--GRSDTATVHINITDAN 891 HSP 4 Score: 123.635 bits (309), Expect = 7.069e-28 Identity = 136/517 (26.31%), Postives = 213/517 (41.20%), Query Frame = 3
Query: 306 KWFPTDVNKLQDFGKPIYKFQFFNC-EKSSVYFEINPLN-------------GVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE---FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLD 1802
K++ +V + Q G P+ + E S +++EI N G+ITI + +D K+ + L + S + I + D N+ +P + E + +G + + A D+D G N YS++ E + + N + +V LDRE Y V A DGGNPS + + V + VTD NDN+P F+ +Y S+ E+ T VIQ+ A D D +NG+I+Y +S + + F I+ SG I LD E+ L A D G+ ST V I + D+ND+ P F + T + EN G +V D D N V H I ++ FSL + P + ++ T+ D E K +V +P + + V D+ND AP + IF+ D P + I A D D ++ L Y I G +A + +N G + L L+
Sbjct: 797 KYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDY------------KQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESING-----LGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGS--FVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPT--FASDKIT--LYVPENSPVGSVVGEIHAHDPDEGVNAVV--HYSIIGGDDSNAFSL--VTRPGSERAQLLTMTELDYESTRKRFELVV--RAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGEIGRIPAFDAD--VSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLN 1282
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 295.819 bits (756), Expect = 1.083e-83 Identity = 242/807 (29.99%), Postives = 360/807 (44.61%), Query Frame = 3
Query: 249 IYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA--KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
++EE P T + L A L D G + E + Y ++ G + T E IDR+ L C K C L+ + D +I IEV+DINDN+P + L E + +G S+ +A D D NG++ Y+++ E + ++ +L++ LDRE D Y+ + A DGGNP S + V + D NDN+P FEK+ Y V EN V+Q+KA D+D NG+IEY + P KL I+ +SG I+V+ LD E + V A D G + S V I++ D NDN+P + + A I+E+ G VA+ V DKD EN VTC L P ++ +R Y + T D E+ IV D GNP +++ S+ V V D ND +P FS + E+ +PG + + A+D D G NA L YSI + +F I+ G+V + LDRE + F AAD G P TA + + V D NDN P F+ VLEN P+ V V D DEG N++ ++++ + ++ IQ + S S DRE + Y ++A D G+PP+S+ + INVLD ND P PS S S +++ P + + + A D D G N+EL YS N +DLF ++P +G+I+L + + H + L++ V D G P A + I +
Sbjct: 29 VHEEQPPSTLIGSLAAD---------QGLPDTG------HLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKD-----CRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLT---AGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDP-VPKLLRIDRSSGIIYVKGPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKR-------KYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDVG--------KFVIQNGTGTILSSIS------------------FDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGN-PHDLFYISPSNGEITLTKELTRKHS-GLHRLVIKVSDRGKPSRHAIALVHIYV 775
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 295.819 bits (756), Expect = 7.617e-83 Identity = 242/807 (29.99%), Postives = 360/807 (44.61%), Query Frame = 3
Query: 249 IYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA--KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
++EE P T + L A L D G + E + Y ++ G + T E IDR+ L C K C L+ + D +I IEV+DINDN+P + L E + +G S+ +A D D NG++ Y+++ E + ++ +L++ LDRE D Y+ + A DGGNP S + V + D NDN+P FEK+ Y V EN V+Q+KA D+D NG+IEY + P KL I+ +SG I+V+ LD E + V A D G + S V I++ D NDN+P + + A I+E+ G VA+ V DKD EN VTC L P ++ +R Y + T D E+ IV D GNP +++ S+ V V D ND +P FS + E+ +PG + + A+D D G NA L YSI + +F I+ G+V + LDRE + F AAD G P TA + + V D NDN P F+ VLEN P+ V V D DEG N++ ++++ + ++ IQ + S S DRE + Y ++A D G+PP+S+ + INVLD ND P PS S S +++ P + + + A D D G N+EL YS N +DLF ++P +G+I+L + + H + L++ V D G P A + I +
Sbjct: 29 VHEEQPPSTLIGSLAAD---------QGLPDTG------HLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKD-----CRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLT---AGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDP-VPKLLRIDRSSGIIYVKGPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKR-------KYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDVG--------KFVIQNGTGTILSSIS------------------FDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGN-PHDLFYISPSNGEITLTKELTRKHS-GLHRLVIKVSDRGKPSRHAIALVHIYV 775
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 290.812 bits (743), Expect = 7.885e-82 Identity = 243/808 (30.07%), Postives = 383/808 (47.40%), Query Frame = 3
Query: 366 QFFNCEKSSVYFEINPLNG-VITIERRIDRDNL--CHLVPTCCPKKNNQCNLDLTIKSDDDF----SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE---PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK-VKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRII----------IESINGDSILSK-ENKMKDNVEYSNEESDNFDF 2702
+ E + Y ++ G + T E IDR++L C + + + C L+ + D +I IE+ D NDN+P +S L E + +G ++ VA D D G+NGI+ Y+++ T E + + + S+++ +L++ LDRE D Y+ + DGG+P S + + +TD NDN P FE++ Y + EN V+Q+KA D+D NG++ Y + + P +L SI+ N+G I V+ +D E + + V+A D G + S V I ++D NDN+P I + A I+E+ G VA+ V D+D EN VTC + P S + + +TL ++R ++ ++ IV D GNP +++ S+ V V D+ND AP FS Y E+ +PG + + ATD D G NA L+YSI G +F IN G+V + + LDRE ++ F AAD G P TA + V V D NDN P F+ V EN P+ V V D DEG N+ ++++ + +I+ N ++ I+ DRE + Y ++A D G+PP+S+ I INVLD ND P P +NS+ K + PRT T + + A D D G NSEL+++ N + LF ++ E G+I+L + H + + L+V VKD G P + TA + I +E + G S+ + E + + +YS + N F
Sbjct: 59 HLYKLEVGAPYLRVDGKTGDIYTTENSIDRESLKDCRNL-----FEGDPCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALT---TGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSP-VMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRI--EIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQ-------------------NGTYT-------ILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKP--ANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGN-PHGLFRISSE-GEITLAKEFTPKH-IGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHVEGLVGHSLYTPLEMDIAGDPDYSRDPHSNILF 824
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh10a (protocadherin 10a [Source:ZFIN;Acc:ZDB-GENE-020731-1]) HSP 1 Score: 290.041 bits (741), Expect = 9.054e-82 Identity = 234/737 (31.75%), Postives = 361/737 (48.98%), Query Frame = 3
Query: 234 HFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK------IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTA--DVP--------LVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKL-IIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAI 2393
HF++ EE R T V ++ D+ KL +FQ ++ Y E+N NG + + RIDR+ +C ++ C L L + ++ + + IEV DINDN P + + ++ + +E + G + A D D GTN +S Y+I+ + ++ T N+ +LVL K LDRE+ +++++ A DGG P G+ ++V V D NDN+P F+++VY +S+ EN T VIQL A D D NG+I Y +SS P LF+I+S +G I V E+DYE +T + V+A DMG + C V++ + D+NDN+PEI F T ++E APG ++A+ SV D+DS ENG++TC L F L+ Y I T DRE+ T +V D+G P +TS S+ V V D ND AP F + Y +V E+ PG Y++ ++A D D G NA ++YSI + + SIN +G ++ D E ++ F A DSG P+ + A + VI+ D NDN P S+ + +N TA +P + ++ TDAD+G N+ +++ R +E +FR ++ G+L R R+ Y+++IE D G PP S+ INVL V+ SG +VK K ++ T I IIA+
Sbjct: 19 HFSVP--EEQERGTVVGNIAED----LGLDITKLS-----ARRFQTVPSSRTP-YLEVNLENGALVVNERIDREEIC--------RQTVPCLLHLEVFLENPL-ELFRVEIEVMDINDNPPSFPETDITVEITESATPGTRFPVENAFDPDVGTNALSTYAITTNNY-----FYLDVQTQGDGNR-FAELVLDKPLDREQQAIHKYVLTAVDGGQPQRTGTALLVVKVLDSNDNAPTFDQSVYSVSLRENSPVGTLVIQLNASDMDEGQNGEIVYSLSSHNSPRIRDLFNIDSRTGRIEVTGEVDYEESSTHQIYVQAKDMGPNAVPAHCKVLVKLIDVNDNTPEISFS----TVTESVSEQAAPGTVIALLSVTDRDSGENGQMTCELH--GEVPFKLKSS---FKNYYTIVTDGPLDREKAESYTLTVVAKDKGVPSLSTSKSIKVHVSDENDNAPRFMQSVYDVYVTENNVPGAYIYAVSAVDPDVGQNAYVTYSILECEIQGMSILTYVSINSENGYLYALRSFDYEQIKEFSFMVHAKDSGAPELTANATVNVIIVDQNDNAP----SVIAPLGKNGTAREHLPRSAEPGYLVTRIVATDADDGENARLSYSIL---------RGNEL---GMFRMDWRT-----------GELRTARRVSSKRDPPHPYDLLIEVRDHGQPPLSSSA--SINVLLVDSVVEGR---SGDRGSVKSKEGSLDLTLIL-IIAL 686 HSP 2 Score: 120.168 bits (300), Expect = 5.847e-27 Identity = 131/473 (27.70%), Postives = 209/473 (44.19%), Query Frame = 3
Query: 1227 VIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTL-KSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK----IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVK--DINDNFPFLP-KSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYS-FKSNNQTNDLFL---MNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
V I + D+NDN P F + T +ITE+ PG V + D D N T + N F L+ + L K DREQ++ + D G P++T + + V V D ND AP F + Y + E+ GT + +NA+D DEG N + YS+ ++ +F+I+ G++ + ++D E + +A D G P + A+ V+VK D+NDN P + ++ V E + ++VTD D G N + L E L SF N ++++ DG L DRE Y + + A D+G P ST I ++V D ND P+F+ S V V V G I + A+D D G+N+ + YS + Q + +N E+G + ++ + ++ + +V KD+G P L A + +II
Sbjct: 106 VEIEVMDINDNPPS--FPETDIT--VEITESATPGTRFPVENAFDPDVGTNALSTYAI--TTNNYFYLDVQTQGDGNRFAELVLDKPLDREQQAIHKYVLTAVDGGQPQRTGTALLVVKVLDSNDNAPTFDQSVYSVSLRENSPVGTLVIQLNASDMDEGQNGEIVYSLSSHNSPRIRDLFNIDSRTGRIEVTGEVDYEESSTHQIYVQAKDMG-PNAVP-AHCKVLVKLIDVNDNTPEISFSTVTESVSEQAAPGTVIALLSVTDRDSGENGQMTCELHGEVPFKL----------------KSSFKN-YYTIVTDGPL-------DREKAESYTLTVVAKDKGVPSLSTSKSIKVHVSDENDNAPRFM---QSVYDVYVTENNVPGAYIYAVSAVDPDVGQNAYVTYSILECEIQGMSILTYVSINSENGYLYALRSF-DYEQIKEFSFMVHAKDSGAPELTANATVNVII 542
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 290.041 bits (741), Expect = 9.206e-82 Identity = 243/808 (30.07%), Postives = 383/808 (47.40%), Query Frame = 3
Query: 366 QFFNCEKSSVYFEINPLNG-VITIERRIDRDNL--CHLVPTCCPKKNNQCNLDLTIKSDDDF----SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE---PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK-VKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRII----------IESINGDSILSK-ENKMKDNVEYSNEESDNFDF 2702
+ E + Y ++ G + T E IDR++L C + + + C L+ + D +I IE+ D NDN+P +S L E + +G ++ VA D D G+NGI+ Y+++ T E + + + S+++ +L++ LDRE D Y+ + DGG+P S + + +TD NDN P FE++ Y + EN V+Q+KA D+D NG++ Y + + P +L SI+ N+G I V+ +D E + + V+A D G + S V I ++D NDN+P I + A I+E+ G VA+ V D+D EN VTC + P S + + +TL ++R ++ ++ IV D GNP +++ S+ V V D+ND AP FS Y E+ +PG + + ATD D G NA L+YSI G +F IN G+V + + LDRE ++ F AAD G P TA + V V D NDN P F+ V EN P+ V V D DEG N+ ++++ + +I+ N ++ I+ DRE + Y ++A D G+PP+S+ I INVLD ND P P +NS+ K + PRT T + + A D D G NSEL+++ N + LF ++ E G+I+L + H + + L+V VKD G P + TA + I +E + G S+ + E + + +YS + N F
Sbjct: 61 HLYKLEVGAPYLRVDGKTGDIYTTENSIDRESLKDCRNL-----FEGDPCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALT---TGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSP-VMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRI--EIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQ-------------------NGTYT-------ILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKP--ANSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGN-PHGLFRISSE-GEITLAKEFTPKH-IGLHRLVVKVKDKGTPPRQTTALVHIYVNETIGNVSHVEGLVGHSLYTPLEMDIAGDPDYSRDPHSNILF 826
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: ENSXETT00000038930.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:19026355:19038271:-1 gene:ENSXETG00000013126.1 transcript:ENSXETT00000038930.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 286.574 bits (732), Expect = 3.413e-82 Identity = 200/580 (34.48%), Postives = 304/580 (52.41%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEI-GDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKL------DGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL--PKSIYLYVLENH-----TADVPLVQVNVTDADEGLNSETKVTLVSETATTLIK 2069
E+S +F +NP NG +T++ RIDR++LC TC L + I +++ + L IE+ DINDNSP +S N+ + +E I G L +A D D G NGIS Y ++P F LS + + LVL+ LDRE+ +++ I+ A DGG P +GS +IV V D NDN PVF K+ Y + + EN + NT + L A D D NG+IEY S T +LF + +G I+++ +DYE L + A D G C + + + D NDN PEI + + + EN A VA F+V+D+DS +NG+VT L P N F ++ PL Y + T + DRE+ S+ + D G+P T + S+ + DIND AP F + +Y ++E+ PG++L T++A D DEG+N+ L+YS+ +FSI+ L G ++ + D E+++ T RA DSG+PK S A ++V V D+NDN+P L PK +++ +A + +++ D D G N+ +LV +T TTL K
Sbjct: 65 LGSERSRRHFALNPANGDLTVKERIDRESLCGSSSTCV--------LPIEIVAENPL-ELYSLEIEIIDINDNSPTFSVNDHIINITELVAIPGIIFPLEIAHDPDVGKNGISQYKLNP-TPYFSLSVKNRKDGTLIPE-----LVLETVLDREEKEEHRLILIALDGGEPPRSGSCNIIVNVLDINDNPPVFHKSNYKVKLLENPKLNTVLTTLNATDQDEGRNGEIEYYFDSHTSESAKELFHLHPQTGEIYIKGIVDYEESNFHELSIRAKDKGVPELEGRCLLQVEVEDANDNPPEIILT----STSTDVPENAALETAVAFFTVRDRDSGKNGEVTLTLSP--NLPFKIK----PLKNHYSLVTDQLLDREKISQYDIQMTAKDLGSPTLQTQVTFSINISDINDNAPVFLQANYNAIIHENKDPGSFLCTVSAFDSDEGVNSELTYSLVDSKIDVFSISSLVYIDPKSGNIYSQRAFDYENIQVFQITVRAEDSGFPKLFSNATVSVFVLDVNDNYPTLLYPKYSRELIIDERIPNSASAGYLVTKISAVDLDSGHNAWLLFSLVDDTDTTLFK 619 HSP 2 Score: 140.198 bits (352), Expect = 2.516e-33 Identity = 137/482 (28.42%), Postives = 213/482 (44.19%), Query Frame = 3
Query: 1233 INIRDLNDNSPEIYFEPSRFTNN---AKITENEA-PGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMN------IPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSY---SIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNN----QTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
I I D+NDNSP F+ N ITE A PG + + D D +NG L P FSL N IP V+ + DRE+K + ++ D G P ++ S ++ V V DIND P F + +Y + E+ K T L T+NATD+DEG N + Y S + AK +F ++ G+++++ +D E + RA D G P+ + V V+D NDN P + S V EN + + V D D G N E +TL + K+ Y + + + LDRE ++Y+I + A D G+P T+ IN+ D+ND P F+ +N + G+ + + A D DEG NSEL YS + + L ++P+SG I Q+ + + + + V +D+G P+L A + + + +N
Sbjct: 120 IEIIDINDNSP-------TFSVNDHIINITELVAIPGIIFPLEIAHDPDVGKNGISQYKLNP--TPYFSLSVKNRKDGTLIPELVLETV-----LDREEKEEHRLILIALDGGEPPRSGSCNIIVNVLDINDNPPVFHKSNYKVKLLENPKLNTVLTTLNATDQDEGRNGEIEYYFDSHTSESAKELFHLHPQTGEIYIKGIVDYEESNFHELSIRAKDKGVPELEGRCLLQVEVEDANDNPPEIILTSTSTDVPENAALETAVAFFTVRDRDSGKNGEVTLTLSPNLPFKIKPLKNHYSL-------------------------VTDQLLDREKISQYDIQMTAKDLGSPTLQTQVTFSINISDINDNAPVFL---QANYNAIIHENKDPGSFLCTVSAFDSDEGVNSELTYSLVDSKIDVFSISSLVYIDPKSGNIYSQRAF-DYENIQVFQITVRAEDSGFPKLFSNATVSVFVLDVN 558 HSP 3 Score: 134.806 bits (338), Expect = 1.332e-31 Identity = 161/604 (26.66%), Postives = 248/604 (41.06%), Query Frame = 3
Query: 909 VAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLK-AIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYI----HVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVT----CHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETD--LDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTV---KVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTA-RLRIIIESINGDSILSKENKMKDNVEY 2672
+ + D NDNSP F +II++ E + + L+ A D D NG +Y+ L Y L G + + LD E LI+ A D G R +C +I+N+ D+NDN P F S + K+ EN ++ + D+D NG++ H A E F L P T I + D E+ + I D+G P + V VED ND P S V E+ T + D+D G N ++ ++ F I L L TD LDRE + A D G P + ++ + DINDN P FL + + EN L V+ D+DEG+NSE +LV + D + I +SL + P I + D E ++I + A D G P + + + VLDVND P ++P S + ++ +G + +I A+D D G N+ L +S + T LF ++ +G++ + +QE + L++ + D+G P L T L + E+ +LS M D Y
Sbjct: 120 IEIIDINDNSPTFSVNDHIINITELVAIPGIIFPLEIAHDPDVGKNGISQYK---LNPTPYFSLSVKNRKDGTLIPELVLETVLDREEKEEHRLILIALDGGEPPRSGSCNIIVNVLDINDNPP--VFHKSNY--KVKLLENPKLNTVLTTLNATDQDEGRNGEIEYYFDSHTSESAKELFHLH----PQTGEIYIKGI--VDYEESNFHELSIRAKDKGVPELEGRCLLQVEVEDANDNPPEIILTSTSTDVPENAALETAVAFFTVRDRDSGKNGEVTLTL--SPNLPFKIKPLKNHYSLVTDQLLDREKISQYDIQMTAKDLGSPTLQTQVTFSINISDINDNAPVFLQANYNAIIHENKDPGSFLCTVSAFDSDEGVNSELTYSLVD-------SKIDVFSI------------SSLVYIDPKSGNIYSQRAFDYENIQVFQITVRAEDSGFPKLFSNATVSVFVLDVNDNYPTLLYPKYSRELIIDERIPNSASAGYLVTKISAVDLDSGHNAWLLFSLVDDTDTT-LFKVSAYTGEVRTIRELQEMDYKEQH-LVISISDHGEPTLSTTVIILSVFQENSKSRDLLSNSKPMTDITLY 687 HSP 4 Score: 86.2705 bits (212), Expect = 1.856e-16 Identity = 94/349 (26.93%), Postives = 164/349 (46.99%), Query Frame = 3
Query: 1629 IFHVNEDVKPGTYL------FTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESV---ESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVT---DADEGLN--SETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNN--QTNDLFLMNPESGKISLQQTI--QESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+F V E+ +PG+ + IN D + L S + + F++N +G + ++ +DRES+ S + P +L + I +I DINDN P + ++ + A +P + + D D G N S+ K+ + ++ RKD +L+P+ ++ E+ LDRE ++ +++ A D G PP+S I +NVLD+ND P F SN VK+ T + + A D+DEG+N E+EY F S+ +LF ++P++G+I ++ + +ES+ + L + KD G+P LE L++ +E N
Sbjct: 31 MFSVGEETEPGSVVGNVAQVLGINLADIAKRRLHLGS----ERSRRHFALNPANGDLTVKERIDRESLCGSSSTCVLPIEIVAENPLELYSLEIEII--DINDNSPTFSVNDHIINITELVA-IPGIIFPLEIAHDPDVGKNGISQYKLNPTPYFSLSVKNRKDG-------------------TLIPE---LVLETVLDREEKEEHRLILIALDGGEPPRSGSCNIIVNVLDINDNPPVF---HKSNYKVKLLENPKLNTVLTTLNATDQDEGRNGEIEYYFDSHTSESAKELFHLHPQTGEIYIKGIVDYEESN---FHELSIRAKDKGVPELEGRCLLQVEVEDAN 344
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh10 (protocadherin 10 [Source:NCBI gene;Acc:779938]) HSP 1 Score: 288.115 bits (736), Expect = 5.554e-81 Identity = 207/654 (31.65%), Postives = 319/654 (48.78%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYI-INTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK---IF---SINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP--------------FLPKSI---YLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLD 2285
Y E+N NGV+ + +IDR+ +C K+N C L L + ++ V IEV DINDN P + Q+++ + SE + G L A D D G N + Y I+ SY ++ T NK +LVLKK+LDRE+ + +++ A DGG P G+ + + V D NDN PVFE+ +Y +S+ EN T VIQL A D D NG++ Y SS P+ +F I+ +G I + ELDYE + + V+A D+G C V++ + DLNDN PEI F T ++E+ +PG +VA+FSV D+DS ENG++ C + + + F R+ + Y I T + DRE + T ++ D G P +++ S+ V V D+ND +P F++ Y +V E+ PG Y+ ++ATDKDE NA +SY I D + +F SIN +G ++ D E ++ F A D G P S A + +I+ D NDN P FLP++ YL+ +V D+DEG N+ +++ +L + + R +T R+ +E+V+E D G PP S+ +I + ++D
Sbjct: 61 YLELNLENGVLYVNEKIDREQIC--------KQNPSCMLHLEVFLENPLEFFRV-EIEVLDINDNPPVFPQSDIQVEISESATPGTRFPLESAYDLDVGNNSLRTYEITTN------SYFNLDVQTQGDGNKF-AELVLKKQLDREQQALHRYVLTAIDGGTPQRTGTALLTIKVLDSNDNVPVFEQQIYTVSLPENSPPGTMVIQLNATDQDEGQNGEVVYSFSSHNSPKVRDIFGIDPRTGRIEIIGELDYEDSGSYQVYVQAKDLGPNAVPVHCKVLVKVLDLNDNPPEISFS----TVKESVSESASPGTVVALFSVTDRDSEENGQIHCEI--LGDVPF---RLKLSYKNYYTIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRFTQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYILECDIQGMSVFTYVSINSENGYLYALRTFDYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAIVSPQGRNGTAKEFLPRTAEPGYLF-----------TRVVAVDSDEGENARLTYSILRGNDMSLFRMDWRTGELRTARKITNK----------------------RDPHRPFELVVEVRDHGQPPLSSTALIQVQIVD 656 HSP 2 Score: 173.326 bits (438), Expect = 2.592e-43 Identity = 169/590 (28.64%), Postives = 259/590 (43.90%), Query Frame = 3
Query: 900 KVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSG----YIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKV----TCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGK----VFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKL--FRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK-VKPRTVS-GTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTI---QESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
+V + V D NDN PVF ++ + ++E+ T A D D N Y+I T Y L G + ++ +LD E ++ A D G +R T + I + D NDN P FE +T + EN PG +V + D+D +NG+V + H P + F ++ P T +I + D E ++ D G V V V D+ND P S + V+E PGT + + TD+D N + I G F + KL K + E LDRE++ + T A D G P ST +I V V D+NDN P ++IY +YV+EN+ + V+ TD DE N+ ++ E IQ + F V+ + N L D E + ++EA D G PP S+ + I ++D ND P + P G N T K PRT G +++A+D DEG+N+ L YS N + LF M+ +G++ + I ++ H+ + L+V V+D+G P L TA +++ I
Sbjct: 105 RVEIEVLDINDNPPVFPQSDIQVEISESATPGTRFPLESAYDLDVGNNSLRTYEI---TTNSYFNLDVQTQGDGNKFAELVLKKQLDREQQALHRYVLTAIDGGTPQRTGTALLTIKVLDSNDNVP--VFEQQIYT--VSLPENSPPGTMVIQLNATDQDEGQNGEVVYSFSSHNSPKVRDIFGID----PRT--GRIEIIGELDYEDSGSYQVYVQAKDLGPNAVPVHCKVLVKVLDLNDNPPEISFSTVKESVSESASPGTVVALFSVTDRDSEENGQIHCEILGDVP--FRL-KLSYKNYYTIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRFTQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYIL------------ECDIQGMSVFTYVSINSENGYLYAL---------RTFDYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAIVSPQGRNGTAKEFLPRTAEPGYLFTRVVAVDSDEGENARLTYSILRGNDMS-LFRMDWRTGELRTARKITNKRDPHRP--FELVVEVRDHGQPPLSSTALIQVQI 654 HSP 3 Score: 130.954 bits (328), Expect = 4.455e-30 Identity = 131/488 (26.84%), Postives = 216/488 (44.26%), Query Frame = 3
Query: 1227 VIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLE-RMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK----IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLP-KSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTL-IKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYS-FKSNNQTNDLFL---MNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII--ESINGDSILSKENK 2651
V I + D+NDN P F S +I+E+ PG + S D D N T E N F+L+ + ++ K DREQ++ + D G P++T + +++ V D ND P F ++ Y + E+ PGT + +NATD+DEG N + YS ++ IF I+ G++ + +LD E S +A D G + V V D+NDN P + ++ V E+ + + +VTD D N + ++ + L + K+ Y I+ E LDRE Y + + A DRG PP S+ I + V DVND P+F + + V V V G I+ + A D+DE +N+ + Y + + Q +F +N E+G + +T + ++ + +V +D G P L A + III ++ N +I+S + +
Sbjct: 106 VEIEVLDINDNPP--VFPQSDI--QVEISESATPGTRFPLESAYDLDVGNNSLRT--YEITTNSYFNLDVQTQGDGNKFAELVLKKQLDREQQALHRYVLTAIDGGTPQRTGTALLTIKVLDSNDNVPVFEQQIYTVSLPENSPPGTMVIQLNATDQDEGQNGEVVYSFSSHNSPKVRDIFGIDPRTGRIEIIGELDYEDSGSYQVYVQAKDLGPNAVPVHCKVLVKVLDLNDNPPEISFSTVKESVSESASPGTVVALFSVTDRDSEENGQIHCEILGDVPFRLKLSYKNYY-------------------------TIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRF---TQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYILECDIQGMSVFTYVSINSENGYLYALRTF-DYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAIVSPQGR 558 HSP 4 Score: 110.923 bits (276), Expect = 5.771e-24 Identity = 123/416 (29.57%), Postives = 169/416 (40.62%), Query Frame = 3
Query: 237 FTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCH---------LVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEIT-EFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQI--SSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAK--ITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMN 1442
+T+ + E P T VI L A TD ++ Q+ G+ +Y F N K F I+P G I I +D ++ L P P H VLV +V D+NDN P S + + SE + G +L D D NG + I ++ +LSY K +V + LDRE + Y V A D G P + + + V V D NDNSP F +A+Y + V EN + + A D D E N I Y I + SI S +GY++ DYE S +VEA D G S TV I I D NDN+P I P AK + PG L D D EN ++T + + + SL RM+
Sbjct: 234 YTVSLPENSPPGTMVIQLNA-------TDQDEGQN-GEVVYSFSSHNSPKVRDIFGIDPRTGRIEIIGELDYEDSGSYQVYVQAKDLGPNAVP------------------VHCKVLV-KVLDLNDNPPEISFSTVKESVSESASPGTVVALFSVTDRDSEENGQIHCEILGDVPFRLKLSY-----------KNYYTIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRFTQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYILECDIQGMSVFTYVSINSENGYLYALRTFDYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAI-VSPQGRNGTAKEFLPRTAEPGYLFTRVVAVDSDEGENARLTYSI--LRGNDMSLFRMD 608
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh10 (protocadherin 10 [Source:NCBI gene;Acc:779938]) HSP 1 Score: 288.115 bits (736), Expect = 6.485e-81 Identity = 207/654 (31.65%), Postives = 319/654 (48.78%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYI-INTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK---IF---SINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP--------------FLPKSI---YLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLD 2285
Y E+N NGV+ + +IDR+ +C K+N C L L + ++ V IEV DINDN P + Q+++ + SE + G L A D D G N + Y I+ SY ++ T NK +LVLKK+LDRE+ + +++ A DGG P G+ + + V D NDN PVFE+ +Y +S+ EN T VIQL A D D NG++ Y SS P+ +F I+ +G I + ELDYE + + V+A D+G C V++ + DLNDN PEI F T ++E+ +PG +VA+FSV D+DS ENG++ C + + + F R+ + Y I T + DRE + T ++ D G P +++ S+ V V D+ND +P F++ Y +V E+ PG Y+ ++ATDKDE NA +SY I D + +F SIN +G ++ D E ++ F A D G P S A + +I+ D NDN P FLP++ YL+ +V D+DEG N+ +++ +L + + R +T R+ +E+V+E D G PP S+ +I + ++D
Sbjct: 61 YLELNLENGVLYVNEKIDREQIC--------KQNPSCMLHLEVFLENPLEFFRV-EIEVLDINDNPPVFPQSDIQVEISESATPGTRFPLESAYDLDVGNNSLRTYEITTN------SYFNLDVQTQGDGNKF-AELVLKKQLDREQQALHRYVLTAIDGGTPQRTGTALLTIKVLDSNDNVPVFEQQIYTVSLPENSPPGTMVIQLNATDQDEGQNGEVVYSFSSHNSPKVRDIFGIDPRTGRIEIIGELDYEDSGSYQVYVQAKDLGPNAVPVHCKVLVKVLDLNDNPPEISFS----TVKESVSESASPGTVVALFSVTDRDSEENGQIHCEI--LGDVPF---RLKLSYKNYYTIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRFTQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYILECDIQGMSVFTYVSINSENGYLYALRTFDYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAIVSPQGRNGTAKEFLPRTAEPGYLF-----------TRVVAVDSDEGENARLTYSILRGNDMSLFRMDWRTGELRTARKITNK----------------------RDPHRPFELVVEVRDHGQPPLSSTALIQVQIVD 656 HSP 2 Score: 173.326 bits (438), Expect = 2.927e-43 Identity = 169/590 (28.64%), Postives = 259/590 (43.90%), Query Frame = 3
Query: 900 KVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSG----YIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKV----TCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGK----VFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKL--FRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK-VKPRTVS-GTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTI---QESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
+V + V D NDN PVF ++ + ++E+ T A D D N Y+I T Y L G + ++ +LD E ++ A D G +R T + I + D NDN P FE +T + EN PG +V + D+D +NG+V + H P + F ++ P T +I + D E ++ D G V V V D+ND P S + V+E PGT + + TD+D N + I G F + KL K + E LDRE++ + T A D G P ST +I V V D+NDN P ++IY +YV+EN+ + V+ TD DE N+ ++ E IQ + F V+ + N L D E + ++EA D G PP S+ + I ++D ND P + P G N T K PRT G +++A+D DEG+N+ L YS N + LF M+ +G++ + I ++ H+ + L+V V+D+G P L TA +++ I
Sbjct: 105 RVEIEVLDINDNPPVFPQSDIQVEISESATPGTRFPLESAYDLDVGNNSLRTYEI---TTNSYFNLDVQTQGDGNKFAELVLKKQLDREQQALHRYVLTAIDGGTPQRTGTALLTIKVLDSNDNVP--VFEQQIYT--VSLPENSPPGTMVIQLNATDQDEGQNGEVVYSFSSHNSPKVRDIFGID----PRT--GRIEIIGELDYEDSGSYQVYVQAKDLGPNAVPVHCKVLVKVLDLNDNPPEISFSTVKESVSESASPGTVVALFSVTDRDSEENGQIHCEILGDVP--FRL-KLSYKNYYTIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRFTQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYIL------------ECDIQGMSVFTYVSINSENGYLYAL---------RTFDYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAIVSPQGRNGTAKEFLPRTAEPGYLFTRVVAVDSDEGENARLTYSILRGNDMS-LFRMDWRTGELRTARKITNKRDPHRP--FELVVEVRDHGQPPLSSTALIQVQI 654 HSP 3 Score: 130.568 bits (327), Expect = 5.174e-30 Identity = 131/488 (26.84%), Postives = 216/488 (44.26%), Query Frame = 3
Query: 1227 VIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLE-RMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK----IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLP-KSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTL-IKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYS-FKSNNQTNDLFL---MNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII--ESINGDSILSKENK 2651
V I + D+NDN P F S +I+E+ PG + S D D N T E N F+L+ + ++ K DREQ++ + D G P++T + +++ V D ND P F ++ Y + E+ PGT + +NATD+DEG N + YS ++ IF I+ G++ + +LD E S +A D G + V V D+NDN P + ++ V E+ + + +VTD D N + ++ + L + K+ Y I+ E LDRE Y + + A DRG PP S+ I + V DVND P+F + + V V V G I+ + A D+DE +N+ + Y + + Q +F +N E+G + +T + ++ + +V +D G P L A + III ++ N +I+S + +
Sbjct: 106 VEIEVLDINDNPP--VFPQSDI--QVEISESATPGTRFPLESAYDLDVGNNSLRT--YEITTNSYFNLDVQTQGDGNKFAELVLKKQLDREQQALHRYVLTAIDGGTPQRTGTALLTIKVLDSNDNVPVFEQQIYTVSLPENSPPGTMVIQLNATDQDEGQNGEVVYSFSSHNSPKVRDIFGIDPRTGRIEIIGELDYEDSGSYQVYVQAKDLGPNAVPVHCKVLVKVLDLNDNPPEISFSTVKESVSESASPGTVVALFSVTDRDSEENGQIHCEILGDVPFRLKLSYKNYY-------------------------TIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRF---TQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYILECDIQGMSVFTYVSINSENGYLYALRTF-DYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAIVSPQGR 558 HSP 4 Score: 110.923 bits (276), Expect = 5.988e-24 Identity = 123/416 (29.57%), Postives = 169/416 (40.62%), Query Frame = 3
Query: 237 FTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCH---------LVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEIT-EFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQI--SSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAK--ITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMN 1442
+T+ + E P T VI L A TD ++ Q+ G+ +Y F N K F I+P G I I +D ++ L P P H VLV +V D+NDN P S + + SE + G +L D D NG + I ++ +LSY K +V + LDRE + Y V A D G P + + + V V D NDNSP F +A+Y + V EN + + A D D E N I Y I + SI S +GY++ DYE S +VEA D G S TV I I D NDN+P I P AK + PG L D D EN ++T + + + SL RM+
Sbjct: 234 YTVSLPENSPPGTMVIQLNA-------TDQDEGQN-GEVVYSFSSHNSPKVRDIFGIDPRTGRIEIIGELDYEDSGSYQVYVQAKDLGPNAVP------------------VHCKVLV-KVLDLNDNPPEISFSTVKESVSESASPGTVVALFSVTDRDSEENGQIHCEILGDVPFRLKLSY-----------KNYYTIVTEGTLDREAMATYTVTVLARDRGTPPLSSTKSIQVQVADVNDNSPRFTQAIYNVYVIENNVPGAYISAVSATDKDEEENANISYYILECDIQGMSVFTYVSINSENGYLYALRTFDYEQLKDFSFMVEARDGGTPPLSSNATVNIIIVDQNDNAPAI-VSPQGRNGTAKEFLPRTAEPGYLFTRVVAVDSDEGENARLTYSI--LRGNDMSLFRMD 608
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: ENSXETT00000038928.1 (protocadherin gamma-C5-like [Source:NCBI gene;Acc:108646236]) HSP 1 Score: 283.108 bits (723), Expect = 5.634e-80 Identity = 210/649 (32.36%), Postives = 332/649 (51.16%), Query Frame = 3
Query: 381 EKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEG-SEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKL------DGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL--PKSIYLYVLE-----NHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLD 2285
E+S +F +NP NG +T+E RIDR++LC ++ C L + I +++ + L IE+ DINDNSP +S N+ + + +E + G L +A D D G NGIS Y +S F LS + + LVL+ LDRE+ +++ I+ A DGG P +GS ++ + V D NDN PVF+K+ Y + + EN + NT + L A D D NG+IEY S T +LF + +G I+++ +DYE L + A D G C + + + D NDN PEI + + + EN A VA F+V+D+DS +NG+VT L P N F ++ PL Y + T + DRE+ S+ + D G+P T + S+ + DIND AP F + +Y ++E+ PG++L T++A D DEG+NA L+YS+ + SI+ L G ++ + D E+++ T RA DSG+PK S A ++V + D+NDN+P L PK +++ + +A + +++ D D G N+ +LV +T TTL K +++ + + IRE L + +VI +D G P ST II +N+++
Sbjct: 68 ERSRRHFVLNPANGDLTVEERIDRESLC--------GSSSTCVLPIEIVAENPL-ELYSLDIEIIDINDNSPTFSINDHIIKITELLTSPGVQFPLEIAHDADVGKNGISQYKLS-TTPYFSLSVKNRKDGTLIPE-----LVLETVLDREEKEEHRLILTALDGGEPPRSGSCQITINVFDINDNPPVFDKSNYKVKLLENPKLNTVLTTLNATDLDEGKNGEIEYYFDSHTSESAKELFYLNPQTGEIYIKGIVDYEESNFHELSIRAKDKGVPEMEGRCLLQVEVEDANDNPPEIILT----STSTDVPENAALETAVAFFTVRDRDSGKNGEVTLSLSP--NLPFKIK----PLKNHYSLVTDQLLDREKISQYDIQMTAKDLGSPTLQTQVTFSLNISDINDNAPVFLQANYNAIIHENKDPGSFLCTVSAFDSDEGVNAELTYSLVDSKIDVVSISSLVYIDPKSGNIYSQRAFDYENIQVFQITVRAEDSGFPKLFSNATVSVYLLDVNDNYPTLLYPKYSRELIIDERIPSSASAGYLVTKISAVDLDSGHNAWLLFSLVDDTDTTLFK--------------VSAYTGEVRT--------IRE--LQETDYKEQRLVISISDHGEPTLSTTVIILVNIIE 667 HSP 2 Score: 138.272 bits (347), Expect = 1.533e-32 Identity = 161/589 (27.33%), Postives = 247/589 (41.94%), Query Frame = 3
Query: 909 VAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLK---AIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIH---VRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVT----CHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETD--LDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTV---KVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKI----SLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRI-IIE 2612
+ + D NDNSP F +II + E L S P +Q A DAD NG +Y++S T P ++ + I + LD E LI+ A D G R +C + IN+ D+NDN P F+ S + K+ EN ++ + D D +NG++ H A E F L P T I + D E+ + I D+G P + V VED ND P S V E+ T + D+D G N ++ S+ F I L L TD LDRE + A D G P + ++ + DINDN P FL + + EN L V+ D+DEG+N+E +LV + D I +SL + P I + D E ++I + A D G P + + + +LDVND P ++P S + ++ +G + +I A+D D G N+ L +S + T LF ++ +G++ LQ+T + + L++ + D+G P L T + + IIE
Sbjct: 120 IEIIDINDNSPTFSINDHIIKITELLTS--PGVQFPLEIAHDADVGKNGISQYKLS--TTPYFSLSVKNRKDGTLIPELVLETVLDREEKEEHRLILTALDGGEPPRSGSCQITINVFDINDNPP--VFDKSNY--KVKLLENPKLNTVLTTLNATDLDEGKNGEIEYYFDSHTSESAKELFYLN----PQTGEIYIKGI--VDYEESNFHELSIRAKDKGVPEMEGRCLLQVEVEDANDNPPEIILTSTSTDVPENAALETAVAFFTVRDRDSGKNGEVTLSL--SPNLPFKIKPLKNHYSLVTDQLLDREKISQYDIQMTAKDLGSPTLQTQVTFSLNISDINDNAPVFLQANYNAIIHENKDPGSFLCTVSAFDSDEGVNAELTYSLVD-------SKIDVVSI------------SSLVYIDPKSGNIYSQRAFDYENIQVFQITVRAEDSGFPKLFSNATVSVYLLDVNDNYPTLLYPKYSRELIIDERIPSSASAGYLVTKISAVDLDSGHNAWLLFSLVDDTDTT-LFKVSAYTGEVRTIRELQETDYKEQR-----LVISISDHGEPTLSTTVIILVNIIE 667 HSP 3 Score: 134.42 bits (337), Expect = 2.789e-31 Identity = 133/482 (27.59%), Postives = 210/482 (43.57%), Query Frame = 3
Query: 1233 INIRDLNDNSPEIYFEPSRFTNN---AKITEN-EAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMN------IPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSY---SIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNN----QTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
I I D+NDNSP F+ N KITE +PG + D D +NG L FSL N IP V+ + DRE+K + + D G P ++ S +++ V DIND P F + +Y + E+ K T L T+NATD DEG N + Y S + AK +F +N G+++++ +D E + RA D G P+ + V V+D NDN P + S V EN + + V D D G N E ++L + K+ Y + + + LDRE ++Y+I + A D G+P T+ +N+ D+ND P F+ +N + G+ + + A D DEG N+EL YS + + L ++P+SG I Q+ + + + + V +D+G P+L A + + + +N
Sbjct: 120 IEIIDINDNSP-------TFSINDHIIKITELLTSPGVQFPLEIAHDADVGKNGISQYKLS--TTPYFSLSVKNRKDGTLIPELVLETV-----LDREEKEEHRLILTALDGGEPPRSGSCQITINVFDINDNPPVFDKSNYKVKLLENPKLNTVLTTLNATDLDEGKNGEIEYYFDSHTSESAKELFYLNPQTGEIYIKGIVDYEESNFHELSIRAKDKGVPEMEGRCLLQVEVEDANDNPPEIILTSTSTDVPENAALETAVAFFTVRDRDSGKNGEVTLSLSPNLPFKIKPLKNHYSL-------------------------VTDQLLDREKISQYDIQMTAKDLGSPTLQTQVTFSLNISDINDNAPVFL---QANYNAIIHENKDPGSFLCTVSAFDSDEGVNAELTYSLVDSKIDVVSISSLVYIDPKSGNIYSQRAF-DYENIQVFQITVRAEDSGFPKLFSNATVSVYLLDVN 558 HSP 4 Score: 95.1301 bits (235), Expect = 4.463e-19 Identity = 99/350 (28.29%), Postives = 166/350 (47.43%), Query Frame = 3
Query: 1629 IFHVNEDVKPGTYL------FTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESV---ESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY----VLENHTADVPLVQVNVTDADEGLN--SETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNN--QTNDLFLMNPESGKISLQQTI--QESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
IF V+E+++PG+ + IN D + L S + + F +N +G + +E +DRES+ S + P +L + +I +I DINDN P + ++ +L + PL + DAD G N S+ K++ + ++ RKD +L+P+ ++ E+ LDRE ++ +++ A D G PP+S I INV D+ND P F SN VK+ T + + A D DEGKN E+EY F S+ +LF +NP++G+I ++ + +ES+ + L + KD G+P +E L++ +E N
Sbjct: 31 IFSVDEEMEPGSVVGNVALALGINLADIAKRRLHLGS----ERSRRHFVLNPANGDLTVEERIDRESLCGSSSTCVLPIEIVAENPLELYSLDIEII--DINDNSPTFSINDHIIKITELLTSPGVQFPLEIAH--DADVGKNGISQYKLSTTPYFSLSVKNRKDG-------------------TLIPE---LVLETVLDREEKEEHRLILTALDGGEPPRSGSCQITINVFDINDNPPVF---DKSNYKVKLLENPKLNTVLTTLNATDLDEGKNGEIEYYFDSHTSESAKELFYLNPQTGEIYIKGIVDYEESN---FHELSIRAKDKGVPEMEGRCLLQVEVEDAN 344
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 282.722 bits (722), Expect = 6.333e-79 Identity = 237/776 (30.54%), Postives = 365/776 (47.04%), Query Frame = 3
Query: 339 DFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNL--CHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLV---IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT---VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEK--SYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK-VKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
D+G P K + E Y ++ G + T E IDR++L C + + +C L+ + D S + L+ IE+ DINDN+P ++ + E + IG + A D D G NG+S Y + I E + +++Q +L++ LDRE+ D Y+ + DGG P+ S + +++ D NDN+P FEK Y + EN V+Q+KA D+D +N +I+Y + +L ++ ++G I V+ +D E T+ V A D G + + V I IRD NDN P I + A I+E+ VA+ V D D N VTC + + F L++++ + Y + T + D E + T IV D GNP +++ S+ V V D+ND AP FS+ +F N D+ + ++ATD D G N+ L YSI + IFSIN G++ + T LDRE E F A D G P TA++ + V D NDN P F+ V+EN P+ V V DAD+G N+ +++ E+ E+ IQ + S S DRE + Y ++A D G+PP+S+ + INVLD ND P + P SN + K + P+T GT + + A D D G N+EL+YS S N +LF ++ +G+++L++ I H + L+V V D G P TA + I
Sbjct: 89 DYGYPDSK-HLYKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNL-----EPGEKCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYEL---IVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASD-TVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVA--GDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDIN--DLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESG--------EFVIQNGTGTILSSIS------------------FDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVP--SNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPF-ELFQISHNNGEVTLEKAIIRKH-YGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 298.901 bits (764), Expect = 1.433e-84 Identity = 237/778 (30.46%), Postives = 366/778 (47.04%), Query Frame = 3
Query: 339 DFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNL--CH-LVPTCCPKKNNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI--SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT---VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
D+G P + E + Y ++ G + T E IDR+ L C +P N C L+ + D ++ IEV+DINDN+P ++ + E + IG + +A D D G NG++ Y + PE E + ++Q +L++ LDRE+ D Y+ + DGGNP S + V V D NDN+P FE+ Y ++EN VIQ+KA D+D N +I+Y PE +L ++ N+G I V+ +D E +T+ V A D G + + V++ ++D+NDN+P I + A I+E+ A VA+ V D+D EN VTC + + F L + + + Y + T D E+ T IV D GNP +++ S+ V V D+ND AP F++ E+ KPG + + A+D D G NA L YS+ + A +F+I+ +G++ ++T LDRE +S AAD G P TA + V V D NDN P F+ V+EN A P+ V V D D+G N+ ++++ + ++ IQ + S S DRE + Y ++A D G PP+S + INVLD ND P PS ++ + + P+T G T++Q+ A D D G N+EL YS N LF + SG I+L++ I+ H + L+V V D G P TA + + +
Sbjct: 58 DYGLPDVG-HLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQIP------GNPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQE-----LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQ--APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNG--------DFVIQNGTGTILSSLS------------------FDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYG-LFQIGSHSGAITLEKEIERRHH-GLHRLVVKVSDRGKPPRYGTALVHLYV 790
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 298.901 bits (764), Expect = 1.433e-84 Identity = 237/778 (30.46%), Postives = 366/778 (47.04%), Query Frame = 3
Query: 339 DFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNL--CH-LVPTCCPKKNNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI--SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT---VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
D+G P + E + Y ++ G + T E IDR+ L C +P N C L+ + D ++ IEV+DINDN+P ++ + E + IG + +A D D G NG++ Y + PE E + ++Q +L++ LDRE+ D Y+ + DGGNP S + V V D NDN+P FE+ Y ++EN VIQ+KA D+D N +I+Y PE +L ++ N+G I V+ +D E +T+ V A D G + + V++ ++D+NDN+P I + A I+E+ A VA+ V D+D EN VTC + + F L + + + Y + T D E+ T IV D GNP +++ S+ V V D+ND AP F++ E+ KPG + + A+D D G NA L YS+ + A +F+I+ +G++ ++T LDRE +S AAD G P TA + V V D NDN P F+ V+EN A P+ V V D D+G N+ ++++ + ++ IQ + S S DRE + Y ++A D G PP+S + INVLD ND P PS ++ + + P+T G T++Q+ A D D G N+EL YS N LF + SG I+L++ I+ H + L+V V D G P TA + + +
Sbjct: 58 DYGLPDVG-HLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQIP------GNPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQE-----LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQ--APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNG--------DFVIQNGTGTILSSLS------------------FDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYG-LFQIGSHSGAITLEKEIERRHH-GLHRLVVKVSDRGKPPRYGTALVHLYV 790
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh10 (protocadherin 10 [Source:MGI Symbol;Acc:MGI:1338042]) HSP 1 Score: 279.641 bits (714), Expect = 8.370e-79 Identity = 214/674 (31.75%), Postives = 318/674 (47.18%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYI-INTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSF-------------------NGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFG---KDAKIF---SINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLS-TANITVIVKDINDNFP----------------FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKL-IIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLD 2285
Y ++N GV+ + +IDR+ +C P+C L L + ++ + + IEV DINDN P + + +L + SE + G L A D D GTN + Y I+P SY ++ T N+ +LVL+K LDRE+ + +++ A DGG G+ + + V D NDN P F++ VY +S+ EN T VIQL A D D NG++ Y SS P +LF + +G + V ELDYE + V+A D+G + C V++ + D NDN+PEI F T ++E APG +VA+FSV D+DS ENG+V C L + + F R+ Y I T DRE T +V D G P +TS S+ V V D+ND AP FS+ Y +V E+ PG Y++ ++ATD+DEG NA L+YSI + +F SIN +G ++ D E ++ F A D+G P+ L+ A + +++ D NDN P LP+S L L +V DAD+G N+ ++V R +E LFR ++ G+L R R+ YE+VIE D G PP S+ + + ++D
Sbjct: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCV--------LHLEVFLENPL-ELFRVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN------SYFSLDVQTQGDGNRF-AELVLEKPLDREQQAVHRYVLTAVDGGGGGGGGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS----TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCEL--LGDVPF---RLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAKLTYSILECQIQGMSVFTYVSINSDNGYLYALRSFDYEQIKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYL--------LTRVAAVDADDGENARLTYSIV---------RGNE---MNLFRLDWRT-----------GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680 HSP 2 Score: 147.132 bits (370), Expect = 2.199e-35 Identity = 165/613 (26.92%), Postives = 258/613 (42.09%), Query Frame = 3
Query: 900 KVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSG----YIHVRWELDYETYTTISLIVEANDMGNL-------------------RRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKV----TCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKL--FRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVL--DVNDCKPKFIFP-SGSNSTV--KVKPRTV-SGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVC-CYVLIVVVKDNGIPRLEDTARLRIIIESING 2624
+V + V D NDN P F + + ++E+ T A D D N +Y+I T Y L G + + LD E ++ A D G +R T + I + D NDN P F+ +T + EN PG LV + D D +NG+V + H+ P A E F L P T ++S D E+ ++ D G V V V D ND AP S + V+E PGT + + TD+D N + + G ++ S K + E LDRE+ +S T A D G P ++ +I V V D+NDN P + +Y +YV EN+ + V+ TD DEG N++ +++ E IQ + F V+ + N L D E + +EA D G+P ++ G +N+L D ND P + P G N T +V PR+ G + ++ A+D D+G+N+ L YS N+ N LF ++ +G++ + + Y L++ V+D+G P L TA L +++ ++G
Sbjct: 107 RVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI---TPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGGGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPA--FDQPVYT--VSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS----PRTGRLEVS--GELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAKLTYSIL------------ECQIQGMSVFTYVSINSDNGYLYAL---------RSFDYEQIKDFSFQVEARDAGSP-QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMN-LFRLDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATL--VVQLVDG 681
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 280.796 bits (717), Expect = 2.969e-78 Identity = 214/689 (31.06%), Postives = 330/689 (47.90%), Query Frame = 3
Query: 582 NDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI--SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT---VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
NDN+P ++ + E + IG + +A D D G NG++ Y + PE E + ++Q +L++ LDRE+ D Y+ + DGGNP S + V V D NDN+P FE+ Y ++EN VIQ+KA D+D N +I+Y PE +L ++ N+G I V+ +D E +T+ V A D G + + V++ ++D+NDN+P I + A I+E+ A VA+ V D+D EN VTC + + F L + + + Y + T D E+ T IV D GNP +++ S+ V V D+ND AP F++ E+ KPG + + A+D D G NA L YS+ + A +F+I+ +G++ ++T LDRE +S AAD G P TA + V V D NDN P F+ V+EN A P+ V V D D+G N+ ++++ + ++ IQ + S S DRE + Y ++A D G PP+S + INVLD ND P PS ++ + + P+T G T++Q+ A D D G N+EL YS N LF + SG I+L++ I+ H + L+V V D G P TA + + +
Sbjct: 1 NDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQE-----LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQ--APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNG--------DFVIQNGTGTILSSLS------------------FDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYG-LFQIGSHSGAITLEKEIERRHH-GLHRLVVKVSDRGKPPRYGTALVHLYV 651 HSP 2 Score: 160.614 bits (405), Expect = 1.915e-39 Identity = 159/611 (26.02%), Postives = 255/611 (41.73%), Query Frame = 3
Query: 513 DLTIKSDDDF----SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNG-ISY-YSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFE-KAVYIIS-------VNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSG---YIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL--EPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL--PKSIYLYVLENHTADVPLV-QVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINV 2279
DLTIK D + +L + V D NDN+P + + + SE S IG S A D+D G N I Y + +PE+ L NT + +DRE + F V A D G + +V+V V D NDN+P E + + +++ ++E++ T V ++ D D N + ++ + + S+S ++ LDYE ++ + A D GN ST ++ + + D+NDN+P ++ EN PG++VA + D DS N ++ L EP A F++ N +I S DREQ+ +V D G+P + +V V V D ND P F Y F V E++ + + + D D+G NA + S+ +D F I G + DRE + F +A D G P + + +T+ V D NDN PF+ P + +L T V QV D D G+N+E L + LF + I E ++R + +V++ +DRG PP+ ++++ V
Sbjct: 86 DLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGP----------VDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVF----TQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPEN------GEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVE-QDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAE------------------------LTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 651 HSP 3 Score: 65.4698 bits (158), Expect = 4.129e-10 Identity = 68/281 (24.20%), Postives = 114/281 (40.57%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEK----AVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTV 1229
F I+P NG I ++ +DR+ + + + + + +++ V D NDN P + + E + +D D G N S+ + +F + T T++ S DRE+ Y F + A DGG P + + V + V DENDN+P + +++ L V Q+ A D DS +N ++ Y I+ Y LF I S+SG I + E++ + L+V+ +D G R T V
Sbjct: 394 FTISPENGEIRVKTSLDREQ----------RDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQN--GTGTILSS----------LSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGET--VSQVTAEDIDSGINAELTYSIAGGNP--YG-LFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALV 647
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdhgb8 (protocadherin gamma subfamily B, 8 [Source:MGI Symbol;Acc:MGI:1935200]) HSP 1 Score: 278.485 bits (711), Expect = 3.679e-78 Identity = 210/666 (31.53%), Postives = 326/666 (48.95%), Query Frame = 3
Query: 327 NKLQDFGKPIYKFQFFNCE--KSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK------IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL------PKSIYLYVLENHTADVP--LVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSL-LPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYI 2273
N +D G P+ N Y +NP NG I + RIDR+ LC P C L L I +++ + V V+ ++DINDN P + QN +V Q +E + G L A+D D G N + Y +S + E S ++ NT K+ +LVL+K LDREK ++ A DGG P G+ ++ + VTD NDN PVF ++ Y +S+ E++ + T V+ + A D D +N ++ Y SL + + F ++ SG I + +D+ET T ++ +EA D G + S C V++ I D NDN+PE+ F + +N+ ITE+ PG +VA+F DKDS ENG+V+C ++ E R+ + YK+ T DREQ + I+ D+G P ++S SV++ V DIND AP F + SY+ V E+ PG + ++A D D G N +SYSI D + S+N+ G VF + D E + S T +A D G P + ++ V+V D NDN P + P L+ + A+ + +V DAD G N+ L V ++ LFSL L G++ + DR+ + + +++ D G PP S +++
Sbjct: 50 NLAEDLGLPVQDLLTRNLRVIAEKPYLSVNPENGNIVVSDRIDREFLCFQSPLCV--------LPLEIVAENPLNVFHVSVV-IEDINDNPPRFLQNSIVLQINELAIPGTRFGLESAIDADVGLNSLQSYQLS--LNE-HFSLVVKDNT---EGKDAPELVLEKPLDREKQSSQLLVLTAVDGGEPVLTGTAQIQIEVTDANDNPPVFSQSTYKVSLREDMAAGTSVLTVIATDQDEGVNAEVTYSFKSLGE-DIRDKFILDHQSGEIKSKGPIDFETKRTYTMNIEAKDGGGM--ASECKVVVEILDENDNAPEVVF--TSVSNS--ITEDAEPGTVVALFKTYDKDSEENGRVSCFVK-----ETVPFRIESSASNYYKLVTDGILDREQTPEYNVTIIATDKGKPPLSSSTSVTLHVGDINDNAPVFHQTSYLIQVAENNPPGASIAQVSAFDPDLGSNGFISYSIIASDLEPKSLWSYVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDQGKPSLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNA------------------------WLSYHVLQASDPGLFSLGLRTGEVRTARALGDRD-SARQRLLVAVRDGGQPPLSATATLHL 663 HSP 2 Score: 142.124 bits (357), Expect = 8.613e-34 Identity = 158/611 (25.86%), Postives = 255/611 (41.73%), Query Frame = 3
Query: 903 VIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGY----IHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIA---NEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVF-LETD--LDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPS---GSNSTVKVKPRTV-SGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKENKMKDNVEYSNEESD 2690
V V + D NDN P F + ++ +NE T AIDAD +N YQ+S E+ L ++ G + + LD E ++ L++ A D G T + I + D NDN P S+ T + E+ A G V D+D N +VT + + ++F L+ + +I + D E K T +I D G + V V + D ND AP S + ED +PGT + DKD N +S F K+ F I + L TD LDRE + T A D G P S+ ++T+ V DINDN P ++ YL V EN+ + QV+ D D G N ++++ D+ S S+ D ++ + D E +++ ++A D+G P S + + V D ND P+ ++P+ ++ + PR G + +++A+D D G N+ L Y + LF + +G++ + + + L+V V+D G P L TA L +I DS+ ++D S+ +S+
Sbjct: 120 VSVVIEDINDNPPRFLQNSIVLQINELAIPGTRFGLESAIDADVGLNSLQSYQLS---LNEHFSLVVKDNTEGKDAPELVLEKPLDREKQSSQLLVLTAVDGGEPVLTGTAQIQIEVTDANDNPPVF----SQSTYKVSLREDMAAGTSVLTVIATDQDEGVNAEVTYSFKSLGEDIRDKFILDHQS------GEIKSKGPIDFETKRTYTMNIEAKDGGG--MASECKVVVEILDENDNAPEVVFTSVSNSITEDAEPGTVVALFKTYDKDSEENGRVS--CFVKETVPFRIESSASNYYKLVTDGILDREQTPEYNVTIIATDKGKPPLSSSTSVTLHVGDINDNAPVFHQTSYLIQVAENNPPGASIAQVSAFDPDLGSNGFISYSIIAS-------------------DLEPKSLWSYVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDQGKPSLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPG-LFSLGLRTGEVRTARALGDRDS-ARQRLLVAVRDGGQPPLSATATLHLIF----ADSLQEVLPDLRDEPLLSDSQSE 688
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q08174|PCDH1_HUMAN (Protocadherin-1 OS=Homo sapiens OX=9606 GN=PCDH1 PE=1 SV=2) HSP 1 Score: 296.204 bits (757), Expect = 1.097e-82 Identity = 241/795 (30.31%), Postives = 372/795 (46.79%), Query Frame = 3
Query: 339 DFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNLCHLVPTCCPKK--NNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI--SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT---VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK--IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARL----------RIIIESINGDSI 2633
D+G P + E + Y ++ G + T E IDR+ L C + + C L+ + D ++ IEV+DINDN+P ++ + E + IG + +A D D G NG++ Y + PE E + ++Q +L++ LDRE+ D Y+ + DGG+P S + V V D NDN+P FE+ Y ++EN VIQ+KA D+D N +IEY PE +L ++ N+G I V+ +D E +T+ V A D G + + V++ ++D+NDN+P I + A I+E+ A VA+ V D+D EN VTC + + F L + + + Y + T D E+ T IV D GNP +++ S+ V V D+ND AP F++ E+ KPG + I A+D D G NA L YS+ + A +F+I+ G++ ++T LDRE ES AAD G P TA + V V D NDN P F+ V+EN A P+ V V D D+G N++ ++++ + ++ IQ + S S DRE + Y ++A D G PP+S + INVLD ND P PS ++ + + P+T G T++Q+ A D D G N+EL YS N LF + SG I+L++ I+ H + L+V V D G P TA + R ++E++ G S+
Sbjct: 80 DYGFPDVG-HLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRE-----CQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE-----LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ--APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV--AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG--------DFVIQNGTGTILSSLS------------------FDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYG-LFQIGSHSGAITLEKEIERRHH-GLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSL 830
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q9P2E7|PCD10_HUMAN (Protocadherin-10 OS=Homo sapiens OX=9606 GN=PCDH10 PE=2 SV=2) HSP 1 Score: 280.411 bits (716), Expect = 2.161e-77 Identity = 212/673 (31.50%), Postives = 316/673 (46.95%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSF-------------------NGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFG---KDAKIF---SINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLS-TANITVIVKDINDNFP----------------FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKL-IIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLD 2285
Y ++N GV+ + +IDR+ +C P+C L L + ++ + + IEV DINDN P + + +L + SE + G L A D D GTN + Y I+P + F L + ++ LVL+K LDRE+ + +++ A DGG G+ + + V D NDN P F++ VY +S+ EN T VIQL A D D NG++ Y SS P +LF + +G + V ELDYE + V+A D+G + C V++ + D NDN+PEI F T ++E APG +VA+FSV D+DS ENG+V C L + + F R+ Y I T DRE T +V D G P +TS S+ V V D+ND AP FS+ Y +V E+ PG Y++ ++ATD+DEG NA L+YSI + +F SIN +G ++ D E ++ F A D+G P+ L+ A + +++ D NDN P LP+S L L +V DAD+G N+ ++V R +E LFR ++ G+L R R+ YE+VIE D G PP S+ + + ++D
Sbjct: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCV--------LHLEVFLENPL-ELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN-SYFSLDVQTQGDGNRFAE-----LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS----TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCEL--LGDVPF---RLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYL--------LTRVAAVDADDGENARLTYSIV---------RGNE---MNLFRMDWRT-----------GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680 HSP 2 Score: 149.828 bits (377), Expect = 3.506e-35 Identity = 166/613 (27.08%), Postives = 258/613 (42.09%), Query Frame = 3
Query: 900 KVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSG----YIHVRWELDYETYTTISLIVEANDMGNL-------------------RRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKV----TCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKL--FRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVL--DVNDCKPKFIFP-SGSNSTV--KVKPRTV-SGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVC-CYVLIVVVKDNGIPRLEDTARLRIIIESING 2624
+V + V D NDN P F + + ++E+ T A D D N +Y+I T Y L G + + LD E ++ A D G +R T + I + D NDN P F+ +T + EN PG LV + D D +NG+V + H+ P A E F L P T ++S D E+ ++ D G V V V D ND AP S + V+E PGT + + TD+D N + + G ++ S K + E LDRE+ +S T A D G P ++ +I V V D+NDN P + +Y +YV EN+ + V+ TD DEG N++ +++ E IQ + F V+ + N L D E + +EA D G+P ++ G +N+L D ND P + P G N T +V PR+ G + ++ A+D D+G+N+ L YS N+ N LF M+ +G++ + + Y L++ V+D+G P L TA L +++ ++G
Sbjct: 107 QVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI---TPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPA--FDQPVYT--VSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS----PRTGRLEVS--GELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSIL------------ECQIQGMSVFTYVSINSENGYLYAL---------RSFDYEQLKDFSFQVEARDAGSP-QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMN-LFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATL--VVQLVDG 681
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q9HC56|PCDH9_HUMAN (Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2) HSP 1 Score: 281.182 bits (718), Expect = 6.183e-77 Identity = 225/723 (31.12%), Postives = 348/723 (48.13%), Query Frame = 3
Query: 423 VITIERRIDRDNLCHLVPTCCPKKNNQCNLDL-TIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEI--YFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKP-RTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPR 2576
+ T RIDR+ LC + N+C +L + +DF +I + I VKD NDN+P + + E + I + A D D G NG+ +Y + + F L I+ T ++ +L++++ LDRE+ D Y + DGG P + + + V V+D NDN PVF++ + + EN T VIQL A DAD N +I Y + P +LF++ + +G I V+ LD E + V A+D + + TV IN+ D+NDN P I + S ++E + +A+ +V DKD++ NGKV C +E F L+ + Y + T D E + + IV D G P + V V +ED ND P F++ V+E+ + G YL TI+ATD+D G NA + Y + G +A F +++ G + DRE E FT A D+G P S A + V V D NDN P F +V EN + + VTDAD G N ++++++ N F L P +I DRE + Y ++ATD G PP+S+ + INV+DVND P I P SN++ K+ P + G+ +A++ A+D D G N+EL+Y+ S N LF ++P +G I+L++ + V + L+V + D G P+
Sbjct: 85 IFTTSNRIDREKLCA---GASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLD-IVETP----EGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIE--REVPFHLKAV---YDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL-GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILND--------------------------NDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP-SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKG-LFRIDPVTGNITLEEKPAPT-DVGLHRLVVNISDLGYPK 762 HSP 2 Score: 152.91 bits (385), Expect = 4.270e-36 Identity = 169/617 (27.39%), Postives = 264/617 (42.79%), Query Frame = 3
Query: 243 IDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLC-HLVPTCCPKKNNQCNLDLTIKSDDDFS--HIIVLVIEVKDINDNSPFWSQNELVTQ------FSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNA---KITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHF----SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLV 2042
+ I E P T VI L A TD + + + Y F + F +N G+IT++R +DR+ H V T+ + D S + I V D+NDN P +++ SE + +L D D NG I E+ F L + + ++ ++ LD E ++ F + A D G PS N + V V + DENDN P+F + V +SV+EN + + + A D DS N I YQ+ A F ++ +G + D E V A D G S VI+ + D NDNSP +FT+N ++EN V V +V D D+ EN VT + N+ F L+ P + + K + SFDREQ+S T + D G P ++++ V++ V D+ND +P S S+ V PG+ + + A D D G+NA L Y+I G + +F I+ + G + LE V +D GYPK L T + ++ +ND + Y+Y L T + PL + N+ D+ + +E +T++
Sbjct: 259 VHIPENAPVGTSVIQLHA-------TDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKV---------------TVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREV-PFHLKAVYDNQYLLETSS---------LLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGP-----NASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSP-------KFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSIL-NDNDNFVLD----PYSGVIKSNV--SFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKL-VPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHT--LVLVFLYVNDT---AGNASYIYDLIRRTMETPLDR-NIGDSSQPYQNEDYLTIM 816 HSP 3 Score: 127.872 bits (320), Expect = 2.414e-28 Identity = 141/585 (24.10%), Postives = 254/585 (43.42%), Query Frame = 3
Query: 963 IISVNENLQSNTPV------IQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYI--------------HVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLTVMY-KISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-----KIFSINKLDGKVFLETDLDRESVESLHFTTRAAD-SGYPKQLSTANITVIVKDINDNFPFL-------PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGL-DREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
I ++ E L N P+ + + I+A + + + Y++ ++K A L + S++G I + + E + + +++ ND L + + I ++D NDN+P PS N I EN + S D D+ NG H E + + F L+ + P + ++ ++ DREQK I D G P+++++ + V V D+ND P F E H+ E+ GT + ++ATD D G NA + Y IFG ++F++N G + ++ LDRE T A+D S P + A +T+ V D+NDN P + P + +Y+ E + + + V+D D +N + I+R+ + ++ ++ D + ++ S L D E T ++ I A+D G P + ++ + + D ND P F P S + R + TTI+ A DED GKN+++ Y N F ++ ++G ++ + + ++ V +DNG P L+ A + + +
Sbjct: 27 IYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL--VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIK-----IKIIVKDTNDNAPMF---PSPVIN-ISIPENTLINSRFPIPSATDPDTGFNG--VQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRY-IFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGK---------VICFIEREVPFHLKAVY----------------DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTIS---ATDEDSGKNADIVYQLGPNAS---FFDLDRKTGVLTASRVFDREEQER-FIFTVTARDNGTPPLQSQAAVIVTV 562
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 278.1 bits (710), Expect = 1.433e-75 Identity = 219/708 (30.93%), Postives = 336/708 (47.46%), Query Frame = 3
Query: 423 VITIERRIDRDNLCHLVPTCCPKKNNQC--NLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSP--EIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQ 2504
+ T RIDR+ LC +P ++ C +++ I D+ F ++ + ++DINDN+P + + E S I +L A+D D G NG+ Y + F L I + +L+++K+LDREK D Y V DGG P + + + V+VTD NDN PVF++ +S+ EN T V QL A DAD N KI + S+L +LF + + +G I ++ LD E L+V A+D G + + V++N+ D+NDN P +I + + + ++EN +A+ +V DKD++ NG+VTC L P+ + +F LE T D E + ++ D G P S + + V+D ND AP F++ + E+ PG L ++ATD D G NA ++Y + G DA FS+++ G + + LDRE + FT A D+G P S + V + D NDN P + Y YV EN + + VTD D G NS ++++ E N F++ +I DRE Y ++A D G +S+ + INV+DVND KP FI P + S V P T GT + Q+IA+D D G N+E+ YS N T DLF ++ E+G I+L +
Sbjct: 84 IFTTGARIDREKLCAGIP-----RDEHCFYEVEVAILPDEIF-RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNMFGLDVIETPE-----GDKMPQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE-------------TAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDE--------------------------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLME 737 HSP 2 Score: 146.747 bits (369), Expect = 3.596e-34 Identity = 157/552 (28.44%), Postives = 241/552 (43.66%), Query Frame = 3
Query: 288 LGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLV-IEVKDINDNSPFWSQNELVTQ------FSEGSEIGDSKSLTVALDNDFGTNG-ISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQL---KAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNA---KITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLE------RMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHF----SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQL 1868
+G T+ TD + + + K + F + F +N G+ITI+ +DR+ N++ L + SD +V + V D+NDN P +V SE + +L D D NG ++ + T+ E+ + + ++SN Q L LD E +Y + A D G P N S + + V DENDN+PVF ++ +S+ EN N+P IQL A DADS N +I Y + PE FS++ +G + V +LD E + A D G S TV ++I D NDNSP FT+N + EN V + +V D D +N VT + N++F+++ R NI SFDRE++ T ++ D G +++S V++ V D+ND P F S SY V PGT +F + A D D G+NA + YSI G + + +F+I++ G + L D + +A D G P L
Sbjct: 264 VGTSVTQLHATDAD-IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE----------TPNHKL---LVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF------TDHEIPFRLRP---VFSN--QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPEN---NSPGIQLTKVSATDADSGPNAEINYLLGPDAPPE----FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP-------VFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNI------------SFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYEL-VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSL 762 HSP 3 Score: 116.701 bits (291), Expect = 6.416e-25 Identity = 124/459 (27.02%), Postives = 200/459 (43.57%), Query Frame = 3
Query: 1239 IRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLT-VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYS----IFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL-------PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRL 2579
I D+NDN+P P+ N I EN A + + D D NG L N F L+ + P M ++ K DRE+K + D G P+++++ + V V D ND P F E + E+ GT + ++ATD D G NA + +S + ++F +N G + ++ LDRE + A+D G + A + V V D+NDN P + P + + + EN + + + VTD D N +VT ++ E P + R V FSN L+ + LD E T +Y I + A D G PP + +++I V D ND P F + S TV + G + ++ A D D G N+E+ Y + F ++ +G +++ + + + K Y+ ++ KDNG+P L
Sbjct: 129 IEDINDNAP---LFPATVIN-ISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNM-FGLDVIETPEGDKMPQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNG--RVTCFTD---------HEIPFR--LRPV---FSNQF--------LLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVF---TQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGMLTVVKKL-DREKEDKYLFTILAKDNGVPPL 550
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q71M42|PC11X_PANTR (Protocadherin-11 X-linked OS=Pan troglodytes OX=9598 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 277.33 bits (708), Expect = 2.387e-75 Identity = 218/708 (30.79%), Postives = 337/708 (47.60%), Query Frame = 3
Query: 423 VITIERRIDRDNLCHLVPTCCPKKNNQC--NLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSP--EIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQ 2504
+ T RIDR+ LC +P ++ C +++ I D+ F ++ + ++DINDN+P + + E S I +L A+D D GTNG+ Y + F L I + +L+++K+LDRE+ D Y V DGG P + + + V+VTD NDN PVF++ +S+ EN T V QL A DAD N KI + S+L +LF + + +G I ++ LD E L+V A+D G + + V++N+ D+NDN P +I + + + ++EN +A+ +V DKD++ NG+VTC L P+ + +F LE T D E + ++ D G P S + + V+D ND AP F++ + E+ PG L ++ATD D G NA ++Y + G DA FS+++ G + + LDRE + FT A D+G P S + V + D NDN P + Y YV EN + + VTD D G NS ++++ E N F++ +I DRE Y ++A D G +S+ + INV+DVND KP FI P + S V P T GT + Q++A+D D G N+E+ YS N T DLF ++ E+G I+L +
Sbjct: 84 IFTTGARIDREKLCAGIP-----RDEHCFYEVEVAILPDEIF-RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGTNGVQNYELIKSQNIFGLDVIETPE-----GDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE-------------TAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDE--------------------------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGN-TRDLFAIDQETGNITLME 737 HSP 2 Score: 147.902 bits (372), Expect = 1.785e-34 Identity = 157/552 (28.44%), Postives = 241/552 (43.66%), Query Frame = 3
Query: 288 LGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLV-IEVKDINDNSPFWSQNELVTQ------FSEGSEIGDSKSLTVALDNDFGTNG-ISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQL---KAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNA---KITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLE------RMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHF----SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQL 1868
+G T+ TD + + + K + F + F +N G+ITI+ +DR+ N++ L + SD +V + V D+NDN P +V SE + +L D D NG ++ + T+ E+ + + ++SN Q L LD E +Y + A D G P N S + + V DENDN+PVF ++ +S+ EN N+P IQL A DADS N +I Y + PE FS++ +G + V +LD E + A D G S TV ++I D NDNSP FT+N + EN V + +V D D +N VT + N++F+++ R NI SFDRE++ T ++ D G +++S V++ V D+ND P F S SY V PGT +F + A D D G+NA + YSI G + + +F+I++ G + L D + +A D G P L
Sbjct: 264 VGTSVTQLHATDAD-IGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE----------TPNHKL---LVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF------TDHEIPFRLRP---VFSN--QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPEN---NSPGIQLTKVSATDADSGPNAEINYLLGPDAPPE----FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP-------VFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNI------------SFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYEL-VLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSL 762 HSP 3 Score: 117.472 bits (293), Expect = 3.362e-25 Identity = 124/460 (26.96%), Postives = 203/460 (44.13%), Query Frame = 3
Query: 1239 IRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLT-VMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYS----IFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL-------PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRL 2579
I D+NDN+P P+ N I EN A + + D D NG + E I ++ F L+ + P M ++ K DRE+K + D G P+++++ + V V D ND P F E + E+ GT + ++ATD D G NA + +S + ++F +N G + ++ LDRE + A+D G + A + V V D+NDN P + P + + + EN + + + VTD D N +VT ++ E P + R V FSN L+ + LD E T +Y I + A D G PP + +++I V D ND P F + S TV + G + ++ A D D G N+E+ Y + F ++ +G +++ + + + K Y+ ++ KDNG+P L
Sbjct: 129 IEDINDNAP---LFPATVIN-ISIPENSAINSKYTLPAAVDPDVGTNG--VQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNG--RVTCFTD---------HEIPFR--LRPV---FSNQF--------LLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVF---TQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGMLTVVKKL-DREKEDKYLFTILAKDNGVPPL 550
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A4Z2CQZ4 (Protocadherin-9 isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_008258 PE=4 SV=1) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 331/815 (40.61%), Postives = 475/815 (58.28%), Query Frame = 3
Query: 357 YKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCP--------KKNNQ---------------CNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFW----------------SQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSY-----------------IINTNTMMYSN---------KEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEP-------IANEE-------------FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETA--TTLIKRKDEY---PIQKLFRDVTKSFSNSL-----FSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQT--NDLFLMNPESGKISLQQTI 2510
+ +Q FN E S YF ++ + GV+ + RRIDRD LC +CC KN+ C LDL I+SDD +S+II + + + DINDNSP W Q+ + SE S IGD+ LT A+D D G+N I Y I P EFEL + I +++ YS+ + +L+L+++ LDRE YEF + A DGG+PS N ++ + V +TD NDNSP+FEK Y + + EN + +TP+IQ+KA D D N +I+Y+ISSLTKPE+ +LF+++ +G+IHV+WE+DYE + I L VEAND G+L R +TC V I + D ND+SPE++FEP+ TN A + ENE PG+LVAVFS QDKDS +NG+V+C L N+E FSL++M++P +++YK++T SFDRE SK+T I C D G PR+ ++GSV+V + D+NDE P FS+ Y F+VNE+ + GT + INATD DEG NA L++ + G +A F INK G + ++ LDRE++ LHF A D+G P ST+++T+ ++D+NDN P + I YVLENHTA + + ++ DAD G N+E TL+ TA + I D P Q ++ K+FS+SL F + DG++ + S LDRE YE+ I D+G P S+ I+ I++LDVND P+FIFPS N+TV V T GT I ++ AIDED +N L Y K N T + LF ++P +G + L++++
Sbjct: 111 HYYQIFNSEPQSKYFHLDSITGVLRVARRIDRDQLCPTFKSCCTYLTDINYFNKNSHLNLMHNSIDNEHMSNCQLDLNIRSDDQYSNIITVSVHIIDINDNSPTWLLGGKSKFLNFPDDKQKQDVMHVYVSESSLIGDAVQLTPAVDQDAGSNNIMKYVIEPHSPEFELEWTSLDRDISMTNLQISSDIQSSDIQSYSDHLIRSPPGPRHELRLIVRSPLDRETKSLYEFNLTAIDGGSPSRNATVNLQVHITDFNDNSPIFEKDTYTVDLRENARPHTPIIQVKASDIDEGSNAQIKYRISSLTKPEFIRLFTLDPITGWIHVQWEVDYEIHKKIILTVEANDGGSLPRSTTCIVEITVLDENDHSPELHFEPAHLTNYAIVPENEKPGRLVAVFSAQDKDSGDNGRVSCRLAETRKWTFDTQNKEKLESLLLNPTETLFSLQQMHMPFSIIYKLTTAYSFDREFISKITVWITCSDYGIPRRNSTGSVAVRISDVNDEPPMFSQTHYYFNVNENTEIGTIINKINATDPDEGENAKLTFWLSGLNANYFDINKATGYLTVQKLLDRETINELHFRVHAEDNGMPSLNSTSDVTITIQDVNDNPPSVMSKIEFYVLENHTASLAIGKITAYDADIGRNAEVTFTLIHCTAYGSKTINSNDSIFHEPYQHHL-NIRKNFSHSLEVMYTFFIAKDGQIYLGRSKLDRESYPLYELTIRVEDQGIPKLSSTTIVLIHILDVNDNTPRFIFPSIGNNTVYVPKETKPGTYITRLHAIDEDSAENGRLTYGIKPNEHTIIDSLFELDPVTGDVILKRSL 924 HSP 2 Score: 113.235 bits (282), Expect = 2.364e-21 Identity = 145/615 (23.58%), Postives = 246/615 (40.00%), Query Frame = 3
Query: 1005 IQLKAIDADSEM-NGKIEYQISSLTKPEYAKLFSIESNSGYIH-----VRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEF----SLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAP--HFSEKSYIFH---VNEDVKPGTYLFTINATDKDEGINALLSYSI--------------------FGKDAKIFSINKLDG------KVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF--------KSNNQTNDLF-----------------------LMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
++ ++D D M N +I I S Y+ I S G H VR LD ET + + A D G+ R +T + ++I D NDNSP FE +T + EN P + D D N ++ + + EF +L+ + + V +++ D E K+ + D G+ ++T+ V + V D ND +P HF E +++ + V E+ KPG + +A DKD G N +S + +FS+ ++ K+ DRE + + +D G P++ ST ++ V + D+ND P ++ Y + V EN + ++N TD DEG N++ L A + D+ K+ G L +++ LDRE + + A D G P ++ + I + DVND P + S V + I +I A D D G+N+E+ ++ K+ N + +F + G+I L ++ + Y L + V+D GIP+L T + I I +N ++
Sbjct: 279 LEWTSLDRDISMTNLQISSDIQSSDIQSYSDHL-IRSPPGPRHELRLIVRSPLDRETKSLYEFNLTAIDGGSPSRNATVNLQVHITDFNDNSP--IFEKDTYT--VDLRENARPHTPIIQVKASDIDEGSNAQIKYRISSLTKPEFIRLFTLDPITGWIHVQWEV------DYEIHKKIILTVEANDGGSLPRSTTCIVEITVLDENDHSPELHF-EPAHLTNYAIVPENEKPGRLVAVFSAQDKDSGDNGRVSCRLAETRKWTFDTQNKEKLESLLLNPTETLFSLQQMHMPFSIIYKLTTAYSFDREFISKITVWITCSDYGIPRRNSTGSVAVRISDVNDEPPMFSQTHYYFNVNENTEIGTIINKINATDPDEGENAKLTFWLSGLNAN--------------YFDINKA----------TGYLTVQKL-LDRETINELHFRVHAEDNGMPSLNSTSDVTITIQDVNDNPPSVM----SKIEFYVLENHTASLAIGKITAYDADIGRNAEVTFTLIHCTAYGSKTINSNDSIFHEPYQHHLNIRKNFSHSLEVMYTFFIAKDGQIYLGRSKLDRESYPLYELTIRVEDQGIPKLSSTTIVLIHILDVNDNT 852 HSP 3 Score: 63.5438 bits (153), Expect = 3.346e-6 Identity = 74/292 (25.34%), Postives = 127/292 (43.49%), Query Frame = 3
Query: 360 KFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSP-------FWSQNELVTQFSEG------SEIGDSKSLTVALDN--DFGTNGI-SYYSISPEITEFEL------SYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVF------EKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDY 1151
K F+ ++ YF+IN G +T+++ +DR+ + L + N +L+ T SD + I ++D+NDN P F+ + G ++IG + +T L + +G+ I S SI E + L S+ + + K+ + + KLDRE YE + D G P + + V++ + D NDN+P F VY V + + T + +L AID DS NG++ Y I LF ++ +G + ++ LDY
Sbjct: 648 KLTFWLSGLNANYFDINKATGYLTVQKLLDRETINELHFRVHAEDNGMPSLNST--SD--------VTITIQDVNDNPPSVMSKIEFYVLENHTASLAIGKITAYDADIGRNAEVTFTLIHCTAYGSKTINSNDSIFHEPYQHHLNIRKNFSHSLEVMYTFFIAKDGQIYLGRSKLDRESYPLYELTIRVEDQGIPKLSSTTIVLIHILDVNDNTPRFIFPSIGNNTVY---VPKETKPGTYITRLHAIDEDSAENGRLTYGIKPNEHTIIDSLFELDPVTGDVILKRSLDY 926
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A4Z2CQW3 (Protocadherin-9 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_008258 PE=4 SV=1) HSP 1 Score: 540.036 bits (1390), Expect = 3.907e-172 Identity = 312/762 (40.94%), Postives = 444/762 (58.27%), Query Frame = 3
Query: 357 YKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCP--------KKNNQ---------------CNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFW----------------SQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSY-----------------IINTNTMMYSN---------KEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEP-------IANEE-------------FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETA--TTLIKRKDEY---PIQKLFRDVTKSFSNSL-----FSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRT 2357
+ +Q FN E S YF ++ + GV+ + RRIDRD LC +CC KN+ C LDL I+SDD +S+II + + + DINDNSP W Q+ + SE S IGD+ LT A+D D G+N I Y I P EFEL + I +++ YS+ + +L+L+++ LDRE YEF + A DGG+PS N ++ + V +TD NDNSP+FEK Y + + EN + +TP+IQ+KA D D N +I+Y+ISSLTKPE+ +LF+++ +G+IHV+WE+DYE + I L VEAND G+L R +TC V I + D ND+SPE++FEP+ TN A + ENE PG+LVAVFS QDKDS +NG+V+C L N+E FSL++M++P +++YK++T SFDRE SK+T I C D G PR+ ++GSV+V + D+NDE P FS+ Y F+VNE+ + GT + INATD DEG NA L++ + G +A F INK G + ++ LDRE++ LHF A D+G P ST+++T+ ++D+NDN P + I YVLENHTA + + ++ DAD G N+E TL+ TA + I D P Q ++ K+FS+SL F + DG++ + S LDRE YE+ I D+G P S+ I+ I++LDVND P+FIFPS N+TV V T
Sbjct: 111 HYYQIFNSEPQSKYFHLDSITGVLRVARRIDRDQLCPTFKSCCTYLTDINYFNKNSHLNLMHNSIDNEHMSNCQLDLNIRSDDQYSNIITVSVHIIDINDNSPTWLLGGKSKFLNFPDDKQKQDVMHVYVSESSLIGDAVQLTPAVDQDAGSNNIMKYVIEPHSPEFELEWTSLDRDISMTNLQISSDIQSSDIQSYSDHLIRSPPGPRHELRLIVRSPLDRETKSLYEFNLTAIDGGSPSRNATVNLQVHITDFNDNSPIFEKDTYTVDLRENARPHTPIIQVKASDIDEGSNAQIKYRISSLTKPEFIRLFTLDPITGWIHVQWEVDYEIHKKIILTVEANDGGSLPRSTTCIVEITVLDENDHSPELHFEPAHLTNYAIVPENEKPGRLVAVFSAQDKDSGDNGRVSCRLAETRKWTFDTQNKEKLESLLLNPTETLFSLQQMHMPFSIIYKLTTAYSFDREFISKITVWITCSDYGIPRRNSTGSVAVRISDVNDEPPMFSQTHYYFNVNENTEIGTIINKINATDPDEGENAKLTFWLSGLNANYFDINKATGYLTVQKLLDRETINELHFRVHAEDNGMPSLNSTSDVTITIQDVNDNPPSVMSKIEFYVLENHTASLAIGKITAYDADIGRNAEVTFTLIHCTAYGSKTINSNDSIFHEPYQHHL-NIRKNFSHSLEVMYTFFIAKDGQIYLGRSKLDRESYPLYELTIRVEDQGIPKLSSTTIVLIHILDVNDNTPRFIFPSIGNNTVYVPKET 871 HSP 2 Score: 112.464 bits (280), Expect = 2.712e-21 Identity = 145/615 (23.58%), Postives = 246/615 (40.00%), Query Frame = 3
Query: 1005 IQLKAIDADSEM-NGKIEYQISSLTKPEYAKLFSIESNSGYIH-----VRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEF----SLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAP--HFSEKSYIFH---VNEDVKPGTYLFTINATDKDEGINALLSYSI--------------------FGKDAKIFSINKLDG------KVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF--------KSNNQTNDLF-----------------------LMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
++ ++D D M N +I I S Y+ I S G H VR LD ET + + A D G+ R +T + ++I D NDNSP FE +T + EN P + D D N ++ + + EF +L+ + + V +++ D E K+ + D G+ ++T+ V + V D ND +P HF E +++ + V E+ KPG + +A DKD G N +S + +FS+ ++ K+ DRE + + +D G P++ ST ++ V + D+ND P ++ Y + V EN + ++N TD DEG N++ L A + D+ K+ G L +++ LDRE + + A D G P ++ + I + DVND P + S V + I +I A D D G+N+E+ ++ K+ N + +F + G+I L ++ + Y L + V+D GIP+L T + I I +N ++
Sbjct: 279 LEWTSLDRDISMTNLQISSDIQSSDIQSYSDHL-IRSPPGPRHELRLIVRSPLDRETKSLYEFNLTAIDGGSPSRNATVNLQVHITDFNDNSP--IFEKDTYT--VDLRENARPHTPIIQVKASDIDEGSNAQIKYRISSLTKPEFIRLFTLDPITGWIHVQWEV------DYEIHKKIILTVEANDGGSLPRSTTCIVEITVLDENDHSPELHF-EPAHLTNYAIVPENEKPGRLVAVFSAQDKDSGDNGRVSCRLAETRKWTFDTQNKEKLESLLLNPTETLFSLQQMHMPFSIIYKLTTAYSFDREFISKITVWITCSDYGIPRRNSTGSVAVRISDVNDEPPMFSQTHYYFNVNENTEIGTIINKINATDPDEGENAKLTFWLSGLNAN--------------YFDINKA----------TGYLTVQKL-LDRETINELHFRVHAEDNGMPSLNSTSDVTITIQDVNDNPPSVM----SKIEFYVLENHTASLAIGKITAYDADIGRNAEVTFTLIHCTAYGSKTINSNDSIFHEPYQHHLNIRKNFSHSLEVMYTFFIAKDGQIYLGRSKLDRESYPLYELTIRVEDQGIPKLSSTTIVLIHILDVNDNT 852
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A1S8XA96 (Cadherin domain protein OS=Opisthorchis viverrini OX=6198 GN=X801_00458 PE=4 SV=1) HSP 1 Score: 541.576 bits (1394), Expect = 5.106e-172 Identity = 313/854 (36.65%), Postives = 465/854 (54.45%), Query Frame = 3
Query: 231 KHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNN---------------------------QCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFW--------------SQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTM--MYSN---------------KEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAP-GKLVAVFSVQDKDSNENGKVTCHL-EP--------------------IANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSN--------SLFSLL--PDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQT--NDLFLMNPESGKISLQQTIQE 2516
+ + I EE P +V +L W K I FQ FN E S YF+++P +G + I RRIDRD LC + +CCP+ +C LDL I+SDD +S+II++ + + D+NDN+P W Q+ + SE S IGDS +L A D D G NGI Y++ PE+ EF+L + ++ + +Y++ + +L+LV+KK LDRE+ Y+ V AFDGG+PS N S + V VTD NDNSP F+K Y + + EN + +T V+Q+ A+D D +NG+I+Y+ S LTKPE+ ++F +++ +G+I V+WE+DYE Y I L VEA D G L R STC V I + D ND++PEI FEP+ TN A + ENE P G+LVAVF+V D+D+ ENG+V C L EP N F L+ M +P +VMYK++T FDRE S++T IVC D G P + TSG+V+V + D+ND P F + + +V EDV G+ LFT+NATD DEG NA L+Y + G D F++N+ +G++ + +DRE SLH A D G P S+A++ V V D+NDN P + + + + ENH A P+ Q+ +D D G N+E +LV A +P++ + N +L++ L DG++ + ++ LDRE Y++V++A D G P S + I +LDVND P F FPS N+TV V T G + + A D D N + Y+ K + Q +DLF ++ ++G++ L++++ +
Sbjct: 44 RKLRVQISEEEPEGQEVANLRFLINGWSENAKGFPNRSAKHIDNFQIFNSEPQSTYFQLDPTSGRLRIARRIDRDQLCPVFHSCCPRSAEDSLSIELDSSDPPANVAGEDVTGQFLPECRLDLNIRSDDQYSNIILVHVHIVDVNDNAPVWPHAADLKGGSEEQNGQHGITVHLSENSLIGDSTNLPSAYDADAGLNGIVRYTLKPEVPEFDLKWTTDSELIGRLYTDEQHLFTHGESQYLGARHELRLVVKKLLDREQCPFYDLTVTAFDGGSPSRNASTPLKVIVTDANDNSPRFQKDTYTVELMENSKPHTSVVQVTALDDDEGVNGRIKYRFSPLTKPEFMRMFKLDAVTGWIRVQWEVDYELYKKIILTVEAVDSGQLPRASTCVVEIVVLDENDHAPEIRFEPAFVTNYALVPENENPAGRLVAVFTVTDRDAGENGRVACQLAEPSRWHFQSPDPKIIKALISADPPNAFFKLQHMQVPFSVMYKLTTAAVFDREAISQITVLIVCSDYGQPPRNTSGAVAVRITDMNDVEPKFPRERFYMNVREDVLVGSILFTVNATDFDEGRNAKLTYWLSGPDMDYFAVNENNGEISVRRPMDRELKSSLHCRIHAVDQGTPPLNSSADVLVSVTDVNDNPPVITERVEFEIKENHAASAPIGQLTASDRDAGRNAEVSFSLVQCLA---------HPLEVMTSSSNAGQGNGSWTRQVETLYTFLVAKDGRIFLGQAKLDRESFPAYDLVVKAEDHGQPRLSATSTVLIRILDVNDNAPTFTFPSSGNNTVYVPRSTEPGLPLTTVQAFDRDSEDNGRVRYTLKGDRQGVHHDLFSLDSQTGELRLRRSVDQ 888 HSP 2 Score: 124.02 bits (310), Expect = 7.230e-25 Identity = 158/673 (23.48%), Postives = 260/673 (38.63%), Query Frame = 3
Query: 897 IKVIVAVTDENDNSPVFEKAVYI--------------ISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEY-----------AKLFSIESN------SGYIHVRWEL--------DYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFS-EKSYIFH---VNEDVKPGTYLFTI-NATDKDEGINALLS--------YSIFGKDAKI-------------FSINKLDG------KVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKS-IYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSF------------KSNN----------QTNDLF-LMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
I V V + D NDN+PV+ A + + ++EN A DAD+ +NG + Y + PE+ +L++ E + S Y+ R EL D E L V A D G+ R ++ + + + D NDNSP F+ +T ++ EN P V + D D NG++ P+ EF RM V I D E K+ + D G + ++ V + V D ND AP E +++ + V E+ P L + TD+D G N ++ + D KI F + + K+ DRE++ + +D G P + ++ + V + D+ND P P+ Y+ V E+ L VN TD DEG N++ L ++ +G++ +R +DRE+ + I A D+G PP ++ + ++V DVND P ++K + I Q+ A D D G+N+E+ +S S+N Q L+ + + G+I L Q + Y L+V +D+G PRL T+ + I I +N ++
Sbjct: 178 ILVHVHIVDVNDNAPVWPHAADLKGGSEEQNGQHGITVHLSENSLIGDSTNLPSAYDADAGLNGIVRYTLKPEV-PEFDLKWTTDSELIGRLYTDEQHLFTHGESQYLGARHELRLVVKKLLDREQCPFYDLTVTAFDGGSPSRNASTPLKVIVTDANDNSPR--FQKDTYT--VELMENSKPHTSVVQVTALDDDEGVNGRIKYRFSPLTKPEFM--RMFKLDAVTGWIRVQWEVDYELYKKIILTVEAVDSGQLPRASTCVVEIVVLDENDHAPEIRFEPAFVTNYALVPENENPAGRLVAVFTVTDRDAGENGRVACQLAEPSRWHFQSPDPKIIKALISADPPNAFFKLQHMQVPFSVMYKLTTAAVFDREAISQITVLIVCSDYGQPPRNTSGAVAVRITDMNDVEPKFPRERFYMNVREDVLVGSILFTVNATDFDEGRNAKLTYWLSGPDMDYFAVNEN------------------------NGEISVRRP-MDRELKSSLHCRIHAVDQGTPPLNSSADVLVSVTDVNDNPPVIT----ERVEFEIKENHAASAPIGQLTASDRDAGRNAEVSFSLVQCLAHPLEVMTSSSNAGQGNGSWTRQVETLYTFLVAKDGRIFLGQAKLDRESFPAYDLVVKAEDHGQPRLSATSTVLIRILDVNDNA 814
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A419QA20 (Protocadherin-1 OS=Clonorchis sinensis OX=79923 GN=PCDH1 PE=4 SV=1) HSP 1 Score: 543.502 bits (1399), Expect = 5.488e-171 Identity = 309/855 (36.14%), Postives = 461/855 (53.92%), Query Frame = 3
Query: 231 KHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNN---------------------------QCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFW--------------SQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINT--NTMMYSNKEQXXXXXXXX---------------XDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAP-GKLVAVFSVQDKDSNENGKVTCHL-EP--------------------IANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSN-----------SLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQT--NDLFLMNPESGKISLQQTIQE 2516
+ + I EE P +V +L W + I FQ FN E S YF+++P +G + I RRIDRD LC + +CCP+ +C LDL I+SDD +S+II++ + + D+NDN+P W Q ++ SE S IGDS +L A D D G NGI Y++ PE+ EF+L + + + +Y++++QL + + LDRE+ Y + AFDGG+PS N S + V VTD NDNSP F+K Y + + EN + +T V+Q+ A+D D +NG+I+Y+ S LTKPE+ ++F++++ +G+I V+WE+DYE Y I L VEA D G L R STC V I + D ND++PEI FEP+ TN A + ENE P G+LVAVF+V D+D+ ENG+V C L EP N F L+ M +P +VMYK++T FDRE S++T IVC D G P + TSG+V+V + D+ND AP F + + +V EDV G+ LFT+NATD DEG NA L+Y + G D F++N+ G++ + +DRE SLH A D G P S+A+I V V D+NDN P + + + + ENH A P+ Q+ +D D G N+E +LV A +P++ L N + F + DG++ + ++ LDRE T Y+++++A D G P + + I +LDVND P F FPS N+TV V T G + + A D D +N + Y+ K + Q +DLF ++ ++G++ L++++ +
Sbjct: 24 RKLRVQISEEEPEGREVANLRFLVNGWSENAKSFPNRSATRIDNFQIFNSEPQSTYFQLDPTSGRLRIARRIDRDQLCPVFHSCCPRSAEDSFPMELDSSDSVTNVAMEDGTGQYLPECRLDLNIRSDDQYSNIILVHVHIVDVNDNAPIWPHAADLKDGNEQRNGQRGIIVHLSENSLIGDSTNLPSAYDADAGLNGIVRYTLKPEVPEFDLKWASDNELSGRLYTDEQQLFTPGESQYLGARHELRLVVKKLLDREQCPFYNLTITAFDGGSPSRNASTPLKVIVTDANDNSPRFQKDTYTVELMENSKPHTSVVQVTALDDDEGVNGRIKYRFSPLTKPEFMRMFTLDAVTGWIRVQWEVDYELYKKIILTVEAVDSGQLPRASTCVVEIVVLDENDHAPEIRFEPAFVTNYALVPENENPAGRLVAVFTVTDRDAGENGRVACQLAEPSRWHFQSPDPKIIKALISADPPNAFFKLQHMQVPFSVMYKLTTAAVFDREVVSQITVLIVCSDYGQPPRNTSGAVAVRITDMNDVAPKFPRERFYMNVREDVLVGSILFTVNATDVDEGRNAKLTYWLSGPDMDYFAVNENSGEISVRRPMDRELKSSLHCRIHAVDQGTPPLNSSADILVSVTDVNDNPPIITERVEFEITENHAASAPVGQLRASDRDAGRNAEVSFSLVQCLA---------HPLEVLTSSSDAGQGNGSWTRQVEMLYTRFLVAKDGRIFLGQAKLDRESYTAYDLIVKAEDHGQPRLTATSTVLIRILDVNDNAPTFTFPSSGNNTVYVPRSTEPGLPLTTVHAFDRDTEENGRVRYNLKGDRQGIHHDLFALDSQTGELRLRRSVDQ 869
BLAST of Protocadherin-1 vs. TrEMBL
Match: H2KQF7 (Protocadherin-1 OS=Clonorchis sinensis OX=79923 GN=CLF_103808 PE=4 SV=1) HSP 1 Score: 543.117 bits (1398), Expect = 6.362e-169 Identity = 310/854 (36.30%), Postives = 462/854 (54.10%), Query Frame = 3
Query: 231 KHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNN---------------------------QCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFW--------------SQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINT--NTMMYSNKEQXXXXXXXX---------------XDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAP-GKLVAVFSVQDKDSNENGKVTCHL-EP--------------------IANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNS--------LFSLL--PDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQT--NDLFLMNPESGKISLQQTIQE 2516
+ ++ I EE P +V +L W + I FQ FN E S YF+++P +G + I RRIDRD LC + +CCP+ +C LDL I+SDD +S+II++ + + D+NDN+P W + ++ SE S IGDS +L A D D G NGI Y++ PE+ EF+L + + + +Y++++QL + + LDRE+ Y + AFDGG PS N S + V VTD NDNSP F+K Y + + EN + +T V+Q+ A+D D +NG+I+Y+ S LTKPE+ ++F++++ +G+I V+WE+DYE Y I L VEA D G L R STC V I + D ND++PEI FEP+ TN A + ENE P G+LVAVF+V D+D+ ENG+V C L EP N F L+ M +P +VMYK++T FDRE S+VT IVC D G P + TSG+V+V + D+ND AP F + + +V EDV G+ LFT+NATD DEG NA L+Y + G D F++N+ G++ + +DRE SLH A D G P S+A+I V V D+NDN P + + + + ENH A P+ Q+ +D D G N+E +LV A +P++ L N L++ L DG++ + ++ LDRE T Y+++++A D G P + + I +LDVND P F FPS N+TV V T G + + A D D +N + Y+ K + Q +DLF ++ ++G++ L++++ +
Sbjct: 24 RKLSVQISEEEPEGREVANLRFLVNGWSENAKSFPNRSATRIDNFQIFNSEPQSTYFQLDPTSGRLRIARRIDRDQLCPVFHSCCPRSAEDSFPMELDSSDSVTNVAMEDGTGQYLPECRLDLNIRSDDQYSNIILVHVHIVDVNDNAPIWPHAADLKDGNEQRNGRRGIIVHLSENSLIGDSTNLPSAYDADAGLNGIVRYTLKPEVPEFDLKWASDNELSGRLYTDEQQLFTPGESQYLGARHELRLVVKKLLDREQCPFYNLTITAFDGGAPSRNASTPLKVIVTDANDNSPRFQKDTYTVELMENSKPHTSVVQVTALDDDEGVNGRIKYRFSPLTKPEFMRMFTLDAVTGWIRVQWEVDYELYKKIILTVEAVDSGQLPRASTCVVEIVVLDENDHAPEIRFEPAFVTNYALVPENENPAGRLVAVFTVTDRDAGENGRVACQLAEPSRWHFQSPDPKIIKALISADPPNAFFKLQHMQVPFSVMYKLTTAAVFDREVVSQVTVLIVCSDYGQPPRNTSGAVAVRITDMNDVAPKFPRERFYMNVREDVLVGSILFTVNATDVDEGRNAKLTYWLSGPDMDYFAVNENSGEISVRRPMDRELKSSLHCRIHAVDQGTPPLNSSADILVSVTDVNDNPPIITERVEFEITENHAASAPVGQLRASDRDAGRNAEVSFSLVQCLA---------HPLEVLTSSSDAGQGNGSWTRQVEMLYTFLVAKDGRIFLGQAKLDRESYTAYDLIVKAEDHGQPRLTATSTVLIRILDVNDNAPTFTFPSSGNNTVYVPRSTEPGLPLTTVHAFDRDTEENGRVRYNLKGDRQGIHHDLFALDSQTGELRLRRSVDQ 868
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh7a (protocadherin 7a [Source:ZFIN;Acc:ZDB-GENE-120206-1]) HSP 1 Score: 303.523 bits (776), Expect = 1.433e-86 Identity = 244/805 (30.31%), Postives = 370/805 (45.96%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITIE-RRIDRDNL--CHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLV---IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI--------SPEITEF---------------ELSYIINTNTMMYS--------NKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEP-SRFT---NNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSL----ERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII-ESINGDSILSKE 2645
F E + +F+I+ + G +T RRIDR+ L C ++ N+C LD + + L I V D+NDN+P + L E IG L A D DFG NGI Y + P E + + ++ ++Q +L++K LDRE D YE ++ DGGNP + + VA+TD NDNSP FE+AVY + EN TPV+Q++A D D +NG++EY + T+ +L ++ SG++ V +D E + + V A D G R TVI+N+RD NDN P + R A + EN VA+ V D+D ENG VTC + + + F+L E N + + T D E T IV D G+P +++ ++ V V DIND AP F++ H E+ PG + T+ A D D G NA ++YS+ F I+ +G + LDRE E F A D G P +A + V V D NDN P F+ + YV EN A+ P+ V VTDADEG N+E + + + + + LFS+ + I + DRE + Y + A D G PP+S + + V D ND P P+ + T+ + P + + T + ++A D D G N++L Y+ N LF + P SG I+L + ++ H+ + L+V V D+G+P L TA + + I ES+ +++ +
Sbjct: 69 FALESGAEFFKIDNVTGELTTSSRRIDREKLPQCQMI-----FDENECFLDFEVSVIGPLQSWVDLFEGRIVVTDVNDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIDRYELVQDSRDQRRPASATMPAGINNGAGDRRRGQEAGSVPAGRSNVFELQVADTPDGQKQPQLIVKGPLDREARDSYELVLRVRDGGNPPRSSQALLRVAITDVNDNSPRFERAVYEAEMGENTPPGTPVLQVRASDRDIGVNGQVEYVFGAATE-SVRRLLRLDEASGWLSVLHRIDREEVSQLRFTVTARDRGQPPRTDRATVILNVRDENDNVPVVEIRKIGRILVRDGAAMVPENVLVDTPVALVQVSDRDQGENGAVTCTV--VGDVPFTLKPAGENRN---KKKFFLHTSALLDYEATRDYTVTIVAVDSGSPSLSSNSTLMVRVVDINDHAPTFAQSLVEVHFAENNAPGERVVTVVAADADSGKNAEIAYSLDPSVNGAFYIDADNGDIRATGALDREQRERYEFRVIARDKGSPSLQGSATVVVQVTDRNDNAPKFVQEVFTFYVKENLLANSPVGMVTVTDADEGENAELCLFVEEDEEEEEAGGRRQ----------------ELFSIENNTGTIFSAASFDRESRSTYTFRVRAVDGGEPPRSATATVSLFVTDENDNAPSVTAPANESYTL-LPPASGARTVVRTVMASDGDAGSNADLRYALVGGNPFQ-LFEIGPSSGVITLAEPLERRHR-GLHRLVVRVNDSGVPSLCATALVHVFINESLTNATLVDAQ 843 HSP 2 Score: 135.961 bits (341), Expect = 6.289e-32 Identity = 178/685 (25.99%), Postives = 267/685 (38.98%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVI-------------VAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQI----------SSLTKP--------------EYAKLFSIESN--------------SGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAP--------HFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGK---DAKIFSINKLDGKVFLETD--LDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSEL-------EYSFKSNNQTNDLFLMNPESGKI-SLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII--ESINGDSILSKENK 2651
DREK+ + + I FD + + VI + VTD NDN+P F V +SV EN T + A D D NG Y++ +S T P E + + SN + V+ LD E + L++ D GN R S + + I D+NDNSP FE R A++ EN PG V D+D NG+V L R++ +S L DRE+ S++ + D G P +T +V + V D ND P + V E+V T + + +D+D+G N ++ ++ G K N+ K FL T LD E+ T A DSG P S + + V V DIND+ P +S+ ++ EN+ +V V DAD G N+E +L N F + D I LDRE +YE + A D+G+P + + V D ND PKF+ T VK ++ + + + D DEG+N+EL E ++ + +LF + +G I S +ES Y V D G P TA + + + E+ N S+ + N+
Sbjct: 95 DREKLPQCQMI---FDENECFLDFEVSVIGPLQSWVDLFEGRIVVTDVNDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIDRYELVQDSRDQRRPASATMPAGINNGAGDRRRGQEAGSVPAGRSNVFELQVADTPDGQKQPQLIVKGPLDREARDSYELVLRVRDGGNPPRSSQALLRVAITDVNDNSPR--FE--RAVYEAEMGENTPPGTPVLQVRASDRDIGVNGQVEYVFGAATESVRRLLRLD---EASGWLSVLHRIDREEVSQLRFTVTARDRGQPPRTDRATVILNVRDENDNVPVVEIRKIGRILVRDGAAMVPENVLVDTPVALVQVSDRDQGENGAVTCTVVGDVPFTLKPAGENRNKKKFFLHTSALLDYEATRDYTVTIVAVDSGSPSLSSNSTLMVRVVDINDHAPTFAQSLVEVHFAENNAPGERVVTVVAADADSGKNAEIAYSLDPSV-------------------------NGAFYIDADNGDIRATGALDREQRERYEFRVIARDKGSPSLQGSATVVVQVTDRNDNAPKFV---QEVFTFYVKENLLANSPVGMVTVTDADEGENAELCLFVEEDEEEEEAGGRRQELFSIENNTGTIFSAASFDRESRST--YTFRVRAVDGGEPPRSATATVSLFVTDENDNAPSVTAPANE 739
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 293.508 bits (750), Expect = 4.278e-83 Identity = 249/832 (29.93%), Postives = 365/832 (43.87%), Query Frame = 3
Query: 174 VGFCFAFQLPENSFESSNHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA--KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
VG+ F L +S S+ + EE P T + L A L D G + E + Y ++ G + T E IDR+ L C K C L+ + D +I IEV+DINDN+P + L E + +G + ++ A D D NG+ Y +S E S + + ++ +L++ LDRE D Y+ +NA DGG PS S + V +TD NDN+P FEK+ Y V+EN V+Q+KA D+D NG+IEY I + P K+ IE ++G I V+ LD E ++ V A D G + ST V I + D NDN+P + + A I+E+ G VA+ V DKD EN VTC L P + ++ Y + T D E+ IV D GNP +++ S+ V V D ND +P FS + E+ +PG + + A D D G NA L YSI + +F I+ G+V + LDRE E F AAD G P TA + + V D NDN P F+ S VLEN P+ V V D D+G N++ ++++ + +++ I+ DRE + Y ++A D G PP+S+ + INVLD ND P PS S S ++ P + + + A D D G N+EL YS N ++LF ++P G+I L + + H + L+V V D G P A + I +
Sbjct: 5 VGWFLLFALLVDSINSA-LGGILYHVREEQPPNTLIGSLAAD---------QGLPDSG------HLYKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKD-----CRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLS---AGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDP-VPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKK-------KYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVEPDVGNFVVQNGT--------------------------GTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGN-PHELFYISPSDGEIKLTKELTRKHG-GLHRLVVKVSDRGKPSRHAIALVHIYV 775
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:103034658]) HSP 1 Score: 294.278 bits (752), Expect = 2.887e-82 Identity = 239/793 (30.14%), Postives = 368/793 (46.41%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNG-VITIERRIDRDNL--CHLVPTCCPKKNNQCNLDL---TIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNK------------------------EQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSP--------EIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
F E S YF+I+ + G + T ERRIDR+ L C ++ N+C +D I + + + + DINDN+P + L E IG L A D DFG NGI Y + + E + + + +T +S K +Q +L++K LDRE+ D YE + DGG+P+ + + V +TD NDNSP FEK+VY + EN P++QLKA+DAD +NG+IEY + T+ +L ++ ++G++ V +D E + + V A D G + T+IINI+D NDN P IY A + E+ +A+ V D+D NG VTC L+P + E + + Y + T D E + IV D G+P +++ S+ V V DIND P F++ + E+ PG + T+ A D D G NA + YS+ IFSI+ G + + T LDRE E F A D G P +A + V+V D NDN P F+ YV EN + P+ V V D+D+G N+E + Y ++ ++ + ++FS + DRE T Y ++A D G+PP+S + + V+D ND P FP S+ T+ + P + T + +IA D D G N++L YS N LF ++P++G ISL +++ H + L+V V D+G+P T + + +
Sbjct: 62 FTLESGSDYFKIDNITGDLSTNERRIDREKLQQCQMI-----FDENECFIDFEVSVIGPAQSWVDLFEGKVIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDGAESSVRRLGSASTDAHSGKRRFDDAQSRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPARSSQAILRVMITDVNDNSPRFEKSVYEADLPENSSPGAPILQLKAMDADVGVNGQIEYVFGAATE-SVRRLLRLDESTGWLSVLHRIDREEVSQLRFTVMARDRGQPPKTDKATMIINIKDENDNVPNIDIRKIGRIYLR----DGVANVAEDVVVDTPIALVQVSDRDKGPNGVVTCTVVGDVPFQLKPASEIEGDMNKKK------YFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDINDNPPIFTKSTVEVSFPENNAPGERVATVVALDADSGKNAEIFYSLDSSVNGIFSIDADSGDIRVNTILDREQTERYEFKVIAKDKGVPVMQGSATVVVLVADKNDNEPKFMQDVFTFYVKENLQPNSPVGMVTVMDSDKGQNAEMSL----------------YIEEEEEIFSIENNTGTIFSTV----------AFDREQKTTYSFRVKAVDGGDPPRSATATVSLFVMDENDNPPSVTFPINSSYTL-LPPSSNIRTVVRTVIATDTDTGVNADLSYSIIGGNPFK-LFEIDPDTGVISLVSKLEQKH-FGLHRLVVQVNDSGVPSQSTTTLVHVYV 809
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 293.893 bits (751), Expect = 4.410e-82 Identity = 249/837 (29.75%), Postives = 367/837 (43.85%), Query Frame = 3
Query: 159 IIKIFVGFCFAFQLPENSFESSNHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNG-VITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA--KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
++ VG+ F L +S S+ + EE P T + L A L D G + E + Y ++ G + T E IDR+ L C K C L+ + D +I IEV+DINDN+P + L E + +G + ++ A D D NG+ Y +S E S + + ++ +L++ LDRE D Y+ +NA DGG PS S + V +TD NDN+P FEK+ Y V+EN V+Q+KA D+D NG+IEY I + P K+ IE ++G I V+ LD E ++ V A D G + ST V I + D NDN+P + + A I+E+ G VA+ V DKD EN VTC L P + ++ Y + T D E+ IV D GNP +++ S+ V V D ND +P FS + E+ +PG + + A D D G NA L YSI + +F I+ G+V + LDRE E F AAD G P TA + + V D NDN P F+ S VLEN P+ V V D D+G N++ ++++ + +++ I+ DRE + Y ++A D G PP+S+ + INVLD ND P PS S S ++ P + + + A D D G N+EL YS N ++LF ++P G+I L + + H + L+V V D G P A + I +
Sbjct: 36 VMDFSVGWFLLFALLVDSINSA-LGGILYHVREEQPPNTLIGSLAAD---------QGLPDSG------HLYKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKD-----CRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLS---AGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDP-VPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKK-------KYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVEPDVGNFVVQNGT--------------------------GTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNS-SFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGN-PHELFYISPSDGEIKLTKELTRKHG-GLHRLVVKVSDRGKPSRHAIALVHIYV 811
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 290.041 bits (741), Expect = 1.918e-81 Identity = 244/762 (32.02%), Postives = 365/762 (47.90%), Query Frame = 3
Query: 348 KPIYK---FQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQC--NLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN-----AKITENEAPGKLVAVFSVQDKDSNENGKVTCH--------LEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIP 2573
KP+YK E S+ + T RIDR+ LC V +C +++ + D+ F ++ + ++DINDN+P + + E + I + + A D D G NGI +Y + ++EF L II T + +L++++ LDRE D + + DGGNP + + + V V+D NDN PVF+ + ++V EN T V QL A DAD N +I + S+ P + F+I+S++G I V+ LD E+ LIV A+D S TVI+N+ D+NDN P I +R+ N ++EN +A+ +V D+D++ NGKVTC+ L+P+ N++F LE T D E + IV D G P TS V + ++D ND AP F + + E+ PGT L I ATD D G NAL+ YS+ G DA F+I+ G + + LDRE E FT A D+G S + +IV+D NDN P + Y YV EN + + VTDAD G N+ VTL ++I KD + I P +I DRE + Y V++A D G ++ + INV+DVND +P F+ PS + S V T G+ + ++ AID D G N+EL+YS + LF ++ +G I+LQ+ I + + + L+V VKD G P
Sbjct: 104 KPVYKTGDVPLVRVEAST--------GEIFTTANRIDRERLCSGV-----FNEKRCFYEIEVAVLPDEIF-RLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLD-IIETP----EGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSI---DTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRLKPVFNDQFLLE-------------TAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSL-GPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNA--IVTL------SIINGKDNFIID------------------PKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRG-LFAIDKTTGNITLQEKIANADQ-GLHRLVVKVKDLGQP 799 HSP 2 Score: 147.902 bits (372), Expect = 1.471e-35 Identity = 160/564 (28.37%), Postives = 248/564 (43.97%), Query Frame = 3
Query: 288 LGAQATKWFPTDVNKLQDFGK-PIYKFQFFN--CEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFS-HIIVLVIEVKDINDNSPFWSQNELVTQ------FSEGSEIGDSKSLTVALDNDFGTNG-ISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHF----SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLH-FTTRAADSGYPKQL-STANITVIVKDINDNFPFL 1925
+G T+ TD D G F F N + +F I+ G+IT+++ +DR+ +N + + + SD + +++ V D+NDN P ++ SE + + +L D D NG ++ Y + F L + N +Q L LD E +Y + A D G P N S V++ + DENDN+PVF + +S+ EN T +I++ A DADS N I Y + P+ F+I+ SG + V LD E S V A D G+ S TV + ++D NDNSP F + + N + EN V + +V D D+ +N VT + + F ++ P T + K + +FDREQ+S T + D G + T+ V++ V D+ND P F S SY V PG+ + + A D D G+NA L YSI G + +F+I+K G + L+ + + LH + D G P+ L S A + + V D N FL
Sbjct: 304 MGTSVTQLHATDA----DLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRE-------------SNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCY--TDHDVPFRLKPVFN---------DQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLG----PDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPA--FTHAEY--NFYVPENLPLYGTVGLITVTDADAGDNAIVTLSIIN-GKDNFIID----PKTGVIKPNI--TFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL-VPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANAD-QGLHRLVVKVKDLGQPESLHSIALVHLFVNDTVSNATFL 822
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 273.092 bits (697), Expect = 6.954e-77 Identity = 241/760 (31.71%), Postives = 368/760 (48.42%), Query Frame = 3
Query: 357 YKFQFFNCEKSSV-YFEINPLNG-VITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIK----SDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPE----ITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYA-----KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAP--GKLVAVFSVQDKDSNENGKVTCHLEPIANEE--FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK-VKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGI 2570
YK E ++ +NP G + R++DR+ LC ++C++D+ + F +I + I V+DINDN+P ++ L E + G + A D D NG+ Y + P ++ FELS N ++ LV++K LDRE+ YE + A DGG+P +GS + + VTD NDNSPVF++A + + EN T V+QL A D D+ N ++ Y++ + T + +LF ++ NSG + V L+ E +I+ A D G +T TV + + D+NDNSP I N I +EA VA+ +V D D NG VTC+ I N E F L+++ P Y + T ++ D E K++ I D G + + SV++ + D ND AP F+E +Y V E+ G +L T++ATD+D NA + Y G DA +F ++ G + L LDRE + FT A D G P A + V V D+NDN P F YV EN + V V D+DEG N +++++ + + LFS+ P+ +I G DRE Y + ++ATD G P +S+ + I+V+D+ND P + P SN+T K V PRT+ GT + ++ A+D D N+EL Y N N LF ++P G I+L + + E+H + L+V V D GI
Sbjct: 71 YKVMLSKAEDAAPPLVRVNPRTGELFAAGRKMDREALC-----GGQDPGDECHVDVQVGVLPVQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETAN-----GEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCY---IYNPEVPFQLKKLTYP--NQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVY-FLGPDAPTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLSILG------------------------TDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMPP-SNTTYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGNPHN-LFHIDPVIGNITLMEPLTETHH-GLHRLVVRVSDIGI 787 HSP 2 Score: 125.946 bits (315), Expect = 1.508e-29 Identity = 165/616 (26.79%), Postives = 245/616 (39.77%), Query Frame = 3
Query: 897 IKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSI---ESNSG----YIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE---------FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEG------------NPRQTTSGSVSVGVEDINDEAP-----HFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKL--DGKVFLET--DLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
I+V + V D NDN+P F V +SV EN + A D DSE NG Y++ + P F + E+ +G Y+ VR LD E + + A D G+ + + IN+ D NDNSP F+ + N +I EN G V D+D+ N +V L F L++ + +TV +RE+ I+ D+G S ++ + DI AP + SE S HVN V I +D D G N ++ I+ + F + KL + LET LD E+ +AAD+G T ++T+ + D NDN P + Y + V EN+ L+ V+ TD D N+E L + T +F + P+ +I LDRE Y I A D+G P + +NVLDVND +P+F S + V +T+ + D DEG+N + S + LF ++PESG I + YVL V D G P T ++ I + IN +S
Sbjct: 137 IEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLP-SDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSP--VFDQAEV--NVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVN------GLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDI--VAPVNGVIYISEAS---HVNLPVA------LITVSDPDIGANGAVTCYIYNPEVP-FQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPT-------------------------MFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRF---SLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLSILGTDN-RQLFSIDPESGMIRSNVGFDREQR-HYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNS 699
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 258.455 bits (659), Expect = 2.950e-72 Identity = 219/767 (28.55%), Postives = 344/767 (44.85%), Query Frame = 3
Query: 405 INPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLV---IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISP------EITEFEL-------SYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVF-EKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQI-SSLTKPEYAKLFSIESNSGYIHVR--WELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSP--EIYFEPSRFT--NNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE-PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKS--------YIFHVNEDVKPGTYLFTINATDKDEGINALLSYS---IFGKD--AKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKS-----IYLYVLENHTADVPLV-QVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIA-QIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNG 2567
+N L+G +++ R+DR+ LC P C + + + S + L+ + V+DIND++P + L SE +G L A+D D GTN I +Y IS ++ F L + L L+++LDRE + YE ++ DGGNP +GS+ + + V D NDN+PVF + + + E+ + T V+QL+A D D+ NG I Y + LT ++ +G + VR +LD ET L+V A D G L R ++ TV + + D NDN+P E+ + KI EN G V + SV D D +G V LE P E S P V + + T + D E+ + ++ D G P+ + ++ + V DIND P F + Y + E+ GT + + ATD D G N ++++ + G + A++FS+N G++ L T LDRE + A D G P++ + A + V V D NDN P F+ S +Y + +E T+ V V+ +D DEG N+ + LV E I + P G ++ LDRE +YE+ + A D G P S + I V D ND P P+ +++ V+ + +G + + A D D G N Y N +FL+N +SG +SL +T+ S + L+V V+D G
Sbjct: 76 VNELSGELSVALRLDREALCMEEPDACRSTGFMHTVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAELAS------PNKVQFLLKTTRLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAGDTP----------------------GGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTNDNAPVITSPNTNDTWKHVRTFSPAGMLVGVSVTANDIDAGDNGRPLYEIIGGNPKG-IFLLNADSGALSLARTVS-SLDEGLHRLVVRVRDRG 812 HSP 2 Score: 142.124 bits (357), Expect = 1.488e-34 Identity = 158/620 (25.48%), Postives = 263/620 (42.42%), Query Frame = 3
Query: 897 IKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKP--EYAKLFSIES------------------NSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNI-PLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFS----EKSYI----FHVNEDVKPGTYLFTINATDKDEGINALLSYSI-FGKDAKIFSINKLDGKVFLETD--LDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL--PKSI-------YLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSL-LPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVK---VKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+ V + V D ND++P F +S++E+ V +AID D+ N Y+IS+ + + +ES + + +R +LD E + L++ D GN + + + I + D NDN+P ++ +P T +ITE+ G V D D+ NG + + +++ T + + + DRE +V D G ++ S +V+V + D ND AP F + Y+ + E++ GT + I+ +D D G + + + F A++ S NK+ + L+T LD E + + + AAD G PK N+ + V DINDN P P SI + + EN A ++ + TDAD G N TL SE A +S + LFSL + G+L + + LDRE +YE+ +EA D G+P + + I+ + VLD ND P F+ S S + + V+ T GT + + D DEG N+ + + + + G + + + Y L V D+G P L + R+ I + N
Sbjct: 128 LDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAP-VFVDPP--TRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAELASPNKV--QFLLKTTRLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTL-SELAG------------------GESVAE-LFSLNMRTGQLTL-ATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAGDTPGGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTN 721 HSP 3 Score: 65.855 bits (159), Expect = 4.338e-11 Identity = 73/305 (23.93%), Postives = 133/305 (43.61%), Query Frame = 3
Query: 1758 INKLDGKVFLETDLDRESV--------ESLHFTTRAADSGYPKQLSTAN-----ITVIVKDINDNFP-FLPKSIYLYVLENHTAD--VPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFK---SNNQTNDLFLMNPESGKISLQQTIQ-ESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIE 2612
+N+L G++ + LDRE++ S F + K ++N + ++V+DIND+ P F + + + E+ VPL + D D G NS + + + L D + + L +RE LDRE YE+++ D GNP S ++ I V+D ND P F+ P V++ + GT++ Q+ A D D G N + YSF ++ T ++ +G ++++ + + + + L+VV +D G +L +A + + +E
Sbjct: 76 VNELSGELSVALRLDREALCMEEPDACRSTGFMHTVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRA--IDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQ-LDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDP--PTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGG--QLSRSASVTVTVE 373
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: si:ch211-199f5.1 (protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]) HSP 1 Score: 231.876 bits (590), Expect = 1.793e-63 Identity = 186/662 (28.10%), Postives = 306/662 (46.22%), Query Frame = 3
Query: 351 PIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEI---YFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-----GKDAKIF-SINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQ----------VNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINV 2279
P F+ + S+ + +G ++ IDR+ C P+C + + C L + ++ +E+ DIND++P ++++E+ + SE +G L A D D G N + Y + E F L+ T+ Y+ LV+K +LDRE+ +Y + A+DGG+P +G+ V + V D NDNSPVF + ++V E+ T ++ L A D D NG++ Y SS E +LF ++ +G + ++ +LD+E + + ++A DMG + C V++++ D+NDN+PEI + SR + ++E A V + +V D DS ENG V CHL + F L +P Y + T S DREQ + + D G P + + +V + D ND P F +Y + E+ PG Y+ T+ A D D N +++Y++ G + SIN G ++ LD E++ SL F +A D G P ++ A ++V + D NDN P + L N T V L + V D+D N E +V L + I +L +V F+N+ + + D T++ +V+ DRG+P S I I V
Sbjct: 60 PSRHFRLMRRDDFSL-VHVEEADGTVSAREVIDREQQCGQAPSCVIRFDVLCTLPRGL------FQLVHAEVELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHLD-ENERFGLALRARTDGAKYAE-----LVVKSRLDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDHELNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSR-GDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLR--GHPHFKL----LPYRDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVVTHP----PLRNGTGVVRLPRDAGLGYLVTVVRARDSDSEANGELSYRIVQGNERNLFR------INRLGGEV---FTNA--ASVTDAA----------ASATRHSLVVMVRDRGSPALSATAAIEIRV 676 HSP 2 Score: 139.813 bits (351), Expect = 6.147e-34 Identity = 146/526 (27.76%), Postives = 230/526 (43.73%), Query Frame = 3
Query: 1095 LFSIESNSGYIHVRWELDYETYT--TISLIVEANDMGNLRRG--STCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKS-FDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGK-DAKIFSINKLD---GKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLP--DGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEY----SFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRL--EDTARLRIIIESIN 2621
L +E G + R +D E S ++ + + L RG + + D+ND++P+ +R + +I+E+ A G V + +D D N HL+ NE F L Y +KS DREQ+ + T + +D G+P ++ + V + V D ND +P F++ S V ED PGT L T+NATD DEG N + YS DA++ + +LD GK+ L+ LD E + +A D G + + V V+DINDN P I L + D V EG E+ V LV+ + I + + R + F LLP D +++ S LDRE Y +V+EA+D G PP+ + +LD ND +P+F + S ++ G + + A D D N + Y S + + +NP SG I + + + + V +D+G+P L T +RI+ E+ N
Sbjct: 74 LVHVEEADGTVSAREVIDREQQCGQAPSCVIRFDVLCTLPRGLFQLVHAEVELLDINDHAPDF----ARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHLD--ENERFGLALRARTDGAKYAELVVKSRLDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDHELNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAP----EIKLDFIMQSRGDTVFVS-------EGAAYESFVGLVT---VSDIDSAENGLVACHLR------GHPHFKLLPYRDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLE---NNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPL-DYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDN 569
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 230.335 bits (586), Expect = 1.523e-61 Identity = 233/789 (29.53%), Postives = 339/789 (42.97%), Query Frame = 3
Query: 288 LGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKI--DKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEY-QISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDM--GNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLK-SFDREQKSKVTAH------IVCFDEGNP--RQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYIN--VLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLR 2600
LG + TD++ FG+ Y F S F ++P +G+I++ +D + T + ++ I + D+NDN+P + ++ V E A D D N YSI P T SY T + Y + L + LD EKI + A DGG+P N ++ IV V DENDNSP+F++ Y I++ EN+ + V+ + A D D EY Q+S + E + F I + SG I LD E + LIV A D GN ++ TV I + D+NDN P P T I EN G + S D D NENG + ++P N + R+N KI T DRE + ++ + D G+P R T S +V+V ++D+ND P F Y V E + + LF + ATD DEG N ++YS+ + F ++ G + LDRE+V + A D G P ST ++++V D+NDN P F P + ++E+ D ++ +N TDAD GLN+E + + ++ + FRD L+ LDRE Y +VIEA D G G ++ VLDVND +P F+ GS V V G I Q+ A D DEG N + Y S NQ + FL+N SG IS T + V + L V +N L R+R
Sbjct: 45 LGTSVVQVLATDLDA-GVFGQVSYHFS-----DDSDKFSLDPASGLISVAAALDFEATPRFTVTVMARDGGGQETAGRVR------------INLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILP--TSAYSSYFSITVSGGYG-----VVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSP----EYGQLSLIYSLEGSTQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVT----IVENTPGGTDIFTVSAADPDLNENGTLVYAIDP-PNPFY---RIN---AASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGG------NQDGQFSVG--FRD----------------GLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFL--EGSYE-VSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGN-FLVNVSSGLISRGATPLDRETVALHALQVEAFNNDSVGLSSVIRVR 765 HSP 2 Score: 179.489 bits (454), Expect = 9.818e-46 Identity = 177/602 (29.40%), Postives = 277/602 (46.01%), Query Frame = 3
Query: 891 GSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTL-KSFDREQ--KSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDE----GINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSG----YPKQLSTANITVIVKDINDNFPF---LPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESG--LDRE------VTTKYEIVIEATDRGNPPKSTKGIIYINVL--DVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKI-SLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
GS +V + + +ENDN P+F +Y +SV EN T V+Q+ A D D+ + G++ Y S + + FS++ SG I V LD+E ++ V A D G + + V IN+ D+NDN+P F+ + A+ EN+ V D+DS N ++T + P + +I ++ Y + TL ++ D E+ ++ I+ D G+P ++ + V V D ND +P F SY + E++ G + +NATD D+ G +L+ YS+ G F IN G + T LDRE+V RA D G ++T NIT++ D+NDN P LP ++ ++EN + V+ D D N TL+ D P +R S GK IR +G LDRE + IV+ DRG+PP+ + VL DVND +P F+ G ++V + +T+ Q+ A D DEG N + YS + D F ++ +G I +L Q +E+ V Y L +V D G P L T L +++ +N
Sbjct: 12 GSARVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQVSYHFS-----DDSDKFSLDPASGLISVAAALDFEATPRFTVTVMARDGGG--QETAGRVRINLLDVNDNTP--VFQRDSYVGTAR--ENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYS---SYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLI-YSLEGSTQ--FRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLL--DVNDNDPAWRDLPYAV--TIVENTPGGTDIFTVSAADPDLNENG------------TLVYAID--PPNPFYRINAAS-----------GK--IRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFV---GLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPD-FQLDAATGLITTLVQLDREA--VAAYQLRLVATDRGTPALSSTTTLSLVVLDVN 559 HSP 3 Score: 172.94 bits (437), Expect = 1.192e-43 Identity = 157/566 (27.74%), Postives = 251/566 (44.35%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIK------VIVAVTDENDNSPVFEKA-VYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTK----PEYAKLFSIESNSGYIHV-RWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL---PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPP--KSTKGIIYINVLDVNDCKPKFI-FPSGSN--STVKVKPRTVSGTTIAQII-AIDEDEGKNSELEYSFKSNNQTN 2456
DRE D Y V + DGG + V V VTDENDNSP FE ++ V E+ T + L A D D+ NG + + + T P+Y + ES + V + + +T I + A D G+ R +T + + + D+NDN P I+ P + + E APG LVA D D+ NG+VT +E ++ S+ P + +++ + DRE ++ T +V D GNP + S V V V+D+NDE P F V E + G+++ T+ AT+ +G N +Y I G F+++ G V L +S E + T A D G P A + V V D+ND+ P P + + E + +V+V D DEG N + + + + +D + FR S +I LDRE Y +++ A+D+G P +ST+ + + + D++D +P FI P G + + + GT + + A+D D G N+ + Y + N+ N
Sbjct: 1792 DREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVP-IFLSPGGYA--VSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIG----PSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLL--KSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGG---VGSRD----WESFRINATS------------GIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVV-LDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNEGN 2328 HSP 4 Score: 172.17 bits (435), Expect = 1.765e-43 Identity = 202/786 (25.70%), Postives = 336/786 (42.75%), Query Frame = 3
Query: 387 SSVYFEINPLNGVITIE--RRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGS-EIGDSKSLTVALDNDFGT--NGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEY------------AKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCT------VIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTC----HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHF-SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDG--KVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTV----KVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTN----DLFLMNPESGKISLQQTI-QESHKVCCYVLIVVVKDNGIP-RLEDTARLRIIIESIN 2621
SS YF I+ G +++ + +DR+ + + L + ++ + + L + V D+NDN+P ++ E S +G S + A+D D G G YSI+ N ++ +V +D E +Y +V A D P S ++ V++ +E D F A Y +++E T V+++ A + K+ ++ L + + A+L I + G I + LD E + L V + D G + T V +N+ D NDNSPE FE T ++ E+ APG L+ V D+D+ NG V+ H ++ L N + ++ F + + IV D G+P ++T+ ++SV V D+ND P F S Y V E PGT + ++ ATD D G N +++ I SI DG +V ++DRE+ + A D G P +A + V+V D+ND P FL + VLE+ + + V T+ +G N+ K Y I + ++ + S L+ +L+ + ++ + ATD G PP + +Y+ VLDVND +P F+ P N TV +V P + I +++A+D DEG+N + YSF + F +N SG IS + + +ES V Y LI++ D G P E T L+++++ I+
Sbjct: 1547 SSAYFLIDRDRGNVSMALGQGLDREGI----------PGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIAS-----------GGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAA--PQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAEL--IAALQGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPE--FEAGSAT-LVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAK-ADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNT-----------------KYTYKIAGIGKNAFTVHATS--GLVTSTRLL--------KSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLP--PNGTVVNITEVMPVVIR---IVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAV--YSLILLASDQGQPVSYESTQPLQVVLDDID 2269 HSP 5 Score: 122.865 bits (307), Expect = 2.391e-28 Identity = 156/599 (26.04%), Postives = 255/599 (42.57%), Query Frame = 3
Query: 891 GSIKVIVAVTDENDNSPVFEKAVYIISVNENLQ-SNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTIS-LIVEANDMGN---LRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL---EPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGIN--ALLSYSI--FGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADS----GYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVN----VTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDRE--VTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEG--KNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIE 2612
+ V++ +TDENDN+P F A Y + + E + V + A D D N ++ Y I S A F I++ +G + LD+E + L+V A D R ST TV +++ D+ND +P +F S + ++E + PG +A F D+DS NG++ + +P EF + + L V + DRE ++ I+ D G P ++ +V V V D++D P F ++E + + A+D +EG N ALL +S F + F + G V++ LDRE V T D+ Y ++ S I I+ D NDN P + Y + EN L +N +DAD G+N+ +L+ ++ + +D +V+ + GLDRE + E+ I D G + + + + VLDVND P F S + ++ P GT++ + A+D D G + YS S ND F ++ +G I I + Y+L+VV D P + LR+ ++
Sbjct: 1154 ATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVS---GNTAATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTP--WFLRS-YEGPIDVSEGQ-PGPRIATFMASDQDSGLNGELEYSIIDGDP--RNEFVISPADGDLRVRRYV----ELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTIL-DENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDR-------GNVSMALGQ----------------GLDREGIPGGRLELTILVQDGGRRNATVR--LGVTVLDVNDNTPTFNVTSQTAHVLENSPAV--GTSVIVVKAMDRDLGVCDAGTVRYSIASGG--NDTFGIDESTGLIVTVAPIDYETR-PEYLLMVVATDQAPPFHTASCELRVSLQ 1708 HSP 6 Score: 119.783 bits (299), Expect = 2.142e-27 Identity = 181/728 (24.86%), Postives = 299/728 (41.07%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQN-ELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI---SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYT--TISLIVEAN-DMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFS----VQDKDSNENGKVTCHLEPIANEEFSL--ERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKP-GTYLFTINATDKDEGI--NALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVK-DINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYP------IQKLFRD----VTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGI--------IYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTND----LFLMNPESGKISLQQTIQES--HKVCCYVLI-VVVKDNGIPRLEDTARLRIIIESIN 2621
+ V D+ND +P++ ++ E SEG + G + +A D D G NG YSI P EF +S L++ +LDRE Y + A D G P N ++ V V V D +DN PVF S++E V +++A DA+ N Q S + + F +S +G ++V LD E ++L V N D + R + +I+ I D NDNSP S+ T A+I EN G ++ V + D D N + L ++ F + +R N+ + + + DRE + + R+ + + V V D+ND P F+ S HV E+ GT + + A D+D G+ + YSI F I++ G + +D E+ A D P ++ + V ++ ++++ F S+ Y A VP T+V A +K + P +QK D +S + L + L G+ I ++ LDRE T Y + + + D G P+ + +Y+NV D ND P+ F +GS + V+V+ GT + + A D D G N + ++ T + ++ ESG +++ + K ++L +V D G P T L +I+ +N
Sbjct: 1270 VHVADVNDVTPWFLRSYEGPIDVSEG-QPGPRIATFMASDQDSGLNGELEYSIIDGDPR-NEFVIS----------PADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVF----SQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALG------QGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSF---SLAAYQAALSEAAVP------------------GTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAAL-QGE-ITTQAALDREATDSYMLTVLSRDGG--PREAIAVLTNKPGAYVYVNVTDENDNSPE--FEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESG-VTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVN 1947 HSP 7 Score: 86.2705 bits (212), Expect = 3.740e-17 Identity = 123/519 (23.70%), Postives = 201/519 (38.73%), Query Frame = 3
Query: 276 KVIDLGAQAT---KWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISP----EITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVF--EKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEY---QISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGN-LRRGSTCTVIINIRDLNDNSPEIYFEPSRFT--NNAKITENEAPGKLVA-VFSVQDKDSNENGKVTCHLEPIANE--EFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQT---TSGS------------VSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF 1733
V++LGA T + TD + + G+ ++ + +K I P +G+I + + D T ++ N L+ + IV V+ V D+ND P + E +G + A +N G N Y I+ T S ++ + ++ S +++ A D G P G + V V D ND+ PVF ++++ E + ++++ A+D D NG + Y + ++ F I + SG I LD E+ SLI+ A+D G + ST + + + D++DN P P + I E+ PG V V D D N + + NE +F+L R + + L DRE I+ NP T T+G V V +EDIND+ P F+ Y V D K G+ L + A D+D G N+++ Y I
Sbjct: 1962 SVVELGAPGTLVASVWATDADAGPN-GQVTFRIESGGGDK----LSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSA-------IVRVL-VDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLLKS-----------------YERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWES-FRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANA-IVYYFIAAGNEGNKFNLSRWGL-------LVVLSDLDREVSPYYA--IIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVFTNHEYTAGVAVDAKVGSELLQLEAVDRDVGNNSIVLYRIL 2439
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 219.164 bits (557), Expect = 4.072e-58 Identity = 188/697 (26.97%), Postives = 309/697 (44.33%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYI-INTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISL-----QQTIQESHKVCCYVLIVVVKDNGIPR-LEDTARLRIIIESIN 2621
LV+ V D+ND++P ++ + SEG+ G A+D D G N YSI ++ +L + ++ +T + + + +DRE ++A D G + V + D ND P+F + Y+ + EN V+ + A D+D NG + Y +Y ++F ++S +G + LD E L+V+A D G+ GST V + + DLNDN P Y P ++ A I ENE G V + D D NG V L F + V +ST S DRE+++ + D G+ R + V++ V D D P F+ Y F V E+V PGT + +++A+ D +NA ++Y I D + FSI G++F +DRE A G + A+++V+V D+N++ P ++ Y + + E+ + V TD D G N E K ++ + F + PDG+L +R LDRE +Y + + A D G P S+ + + VLDVND KP F + S+ G+ + + A D D G N + YSF+ Q N F ++ E+G+I+ ++ + + VV D G P+ L+D A +++ ++ +N
Sbjct: 327 LVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSI---VSGNDLGWFSVDESTGLVTTDGK--------VDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFY--PVQYF--ASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVN------AVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLD--LNANVTYLIVSGDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGGVAGE---ASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKY------------------------EIGEGNGGEKFGIFPDGQLYVRYE-LDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLF---NSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFE-KPQVN--FELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVN 966 HSP 2 Score: 214.157 bits (544), Expect = 1.641e-56 Identity = 194/708 (27.40%), Postives = 313/708 (44.21%), Query Frame = 3
Query: 564 IEVKDINDNSP-FWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYS------------ISPE-ITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEI---YFEPSRFTNNAKITENEAPGKLVAVFSVQDKDS-NENGKVTCHLEPIANEE---FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNP-RQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQ--KLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
+ V D+NDN+P F + F E + +G L A+D D G NG+++++ + P +T+ ++ T + DRE Y V A DGG+P G ++V V V D NDN P FEK Y SV E+ +PV + + + L P + +G + R LD+E +L + A D GN T +I + D+NDN P I Y P+ +A + E+ APG + A+ +V D DS NG+++ + + E F L +P + K+++ DRE+ I+ D G P ++ + S+ V V D+ND AP F+ +Y ++E G+Y+ + A D D G+NA L YSI G D FS+++ G V + +DRE S+ A D G + + ++TV + D+ND P ++ Y+ +EN + +V V+ D+D G N + + P Q ++FR L SL GK+ +S LDRE +Y +V++A DRG+PP + + + V D+ND P F S ++ +P T + + A D D G N + Y + + F +N +G +S + ++ + Y L V D G R A + I +
Sbjct: 11 VVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPL----------------DREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAED----SPV--------GAALRDLLHRGRGPLAVP-------FDPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPA--ARSASVDESAAPGTVAALVTVTDADSPTANGELSVSI--VGGNERGHFVLHAPGVPGLRVLKVAS--QLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNF-----------DPDMPAQYREMFR---------LDSLT--GKVTTLKS-LDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGG---TAVTTVTATDPDRGANGTVRYQLTAGDAAR--FQVNAVTGAVSTRVSLDREER-AVYQLQVTALDGGHLRARSPAIVTITV 648 HSP 3 Score: 206.838 bits (525), Expect = 3.694e-54 Identity = 178/596 (29.87%), Postives = 266/596 (44.63%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE-PIANEEFSLERMNIPLTVMYKISTLKSFDREQ------KSKVTAHIVCFDEGNPRQTTS-GSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI-FGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSET--ATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIP 2573
DRE+ Y+ V A GG G V V V D N+++PVF++A Y +S+ E+ N+ ++A D DS NG+++Y+I E +F G ++VR+ELD ET SL V A D G S+ TV + + D+NDN P F S + + E + G LV D D+ NG VT E P N E E +I++L+ FDRE + + +V D G P+ +V V V+D+ND P F++ Y V+E T L + A+D DEG+N L Y+I G + F+++ G++ L LDRE S A DSG ++ + V V D NDN P +S+ + LE+ L+ + +D D G + + + +V+ AT I R + S+F + R LD E Y + + A D G PP+S+ I+ ++V D ND P F+ S ++ P GT + + A D D N EL YS F ++PESG+I I + + V D IP
Sbjct: 720 DREEQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFP----DGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKP--LFNSSSYVFH--FCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSE--------TGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRS----------------TGSVF--------LARR--LDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIP---IGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIP 1267 HSP 4 Score: 201.83 bits (512), Expect = 1.043e-52 Identity = 169/590 (28.64%), Postives = 261/590 (44.24%), Query Frame = 3
Query: 882 SFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAP-GK----LVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNI-PLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGY--PKQLSTA-NITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
SFN +V ++V D NDN PVF + V EN + L A DAD N + Y + L+ E A F +++ SG + LD E + L V A+D + + + + +RD NDNSP SR + + E+ AP GK ++ D DS G+VT L P + +++ + P+T ++ + DRE ++ D G + + V V D ND AP S V ED PGT L I+ATD DEG+NA L +SI D + F++ DG++ + LDRE + R +D P +LS+A +++I+ D+NDN P E+ + V D D G NS + L ++ L VT ++RE LDRE Y + + A D+G PP ++ + + V D ND P+F + + +P GT + ++ A D DEG N EL Y S + T D F ++P G +++ + + + + Y L V +D G P DTA +R+ + +N
Sbjct: 1498 SFN---QVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSV--LSGSEGA--FVVDAASGVLRASRRLDREERASYLLTVRASDGTH---ATDARLSVAVRDANDNSPRF----SRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVT--RPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGN-DGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFAL-NTVTGEVR------------LVRE--LDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEP---PGTEVLRLSAWDPDEGANGELRYDIASGDPTGD-FRLDPVLGTLAVARPL-DRERTASYELAVRARDGGGPARSDTASVRVTLSDVN 2048 HSP 5 Score: 196.052 bits (497), Expect = 8.142e-51 Identity = 184/691 (26.63%), Postives = 306/691 (44.28%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQ-----LKAIDADSEMNGKIEYQISSLTKPEYA-KLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMN----IPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGN---PRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF----------GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTT-IAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKD 2561
I V+D+NDN P ++ E+ + E + G+ A D D G N + YS+ ++ E +++++ + + +L DRE+ Y V A DG + + ++ VAV D NDNSP F + Y V E+ + + + A DADS G++ Y ++ ++A F + +G ++V LD E+ L A D G L +T + +N+ D NDN+P + + + A++ E+ PG + S D D N ++ EFS+ + + ++S ++ DRE++S + D R +++ VS+ + D+ND AP F+ ED G + T+ A D D G N+ + Y++ G F++N + G+V L +LDRE+ +S T A D G P STA + V V D NDN P P+ Y + E+ +++++ D DEG N E + + S D T F L +L G L + LDRE T YE+ + A D G P +S + + + DVNDC P F S TV + T I Q++A D+D G + ++ Y+ N F ++P+ G + L +++ + +VLI+ D
Sbjct: 1504 ISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSV---LSGSEGAFVVDAASGVLRASRRL--------DREERASYLLTVRASDGTHAT---DARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGL--AATARLYVNVLDANDNAPSVQND----SLAAEVPEDAPPGTSLLRISATDDDEGVNAEL----------EFSISSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSAL-APEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASG-------------------DPTGDFR--LDPVL--GTLAVARP-LDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQL---SPYTVHARENTQGPPVLILQVVARDDDLGSSGQVTYAAAGGNDGG-AFSVSPD-GHVHLLRSLDREAQ-PQHVLIITATD 2133 HSP 6 Score: 184.882 bits (468), Expect = 1.881e-47 Identity = 201/739 (27.20%), Postives = 316/739 (42.76%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISP-EITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL-EPIANEEFSLERMNIP---LTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESV------ESLHFTTRAADSGYPKQLS-TANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQ-ESHKVCCYVLIVVVKDNGIP 2573
F ++ L G +T + +DR+ L + L T K + + V D+NDN P + + E G + + A D D G NG Y ++ + F+++ + + S LDRE+ Y+ V A DGG+ V + V D D P F + Y V EN+ T V + A D +N + Y I S + FSIE + G I +D E L V AN G +V + + D+N+++P F+ R + I E+E DKDS +NG+V + E E+F + P L V Y++ DRE + + + + D G ++S +V+V V D+ND P F+ SY+FH E+ + G+ + + ATD D G N ++YS F K F ++ G++ DRE++ S F+ A D G PK L A + V V+D+NDN P KS+Y V E+ + L++V +D DEG+N + I +E T S +LL LDRE T Y +V+ ATD G P + + + VLD ND P+F + S +V T G + + A DED G + ++ Y+ + N T+ F ++ +G + L + + E+ ++ Y L V +D G P
Sbjct: 497 FRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAK----------VTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVS------------LDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLD--LNANVTYLIVS---GDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAP--VFD--RASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGI----FPDGQLYVRYEL------DRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYS-FEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYA---------INEGNEG------GKFTVDASTGQITLL---------GSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRF---TESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGN-THATFAIDRSTGSVFLARRLDFETQRL--YRLNVSAEDGGRP 1160 HSP 7 Score: 176.407 bits (446), Expect = 9.494e-45 Identity = 169/633 (26.70%), Postives = 272/633 (42.97%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIK-SDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTV-----ALDNDFGTNGISYYSISP-EITEF-ELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGN---LRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLE----------PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATD 2231
F ++ +GV+ RR+DR+ + LT++ SD + L + V+D NDNSP +S++ +E + + V A D D G G Y+++P E +++ + ++ ++ T + + + LDRE Y A DGG + ++ V V D NDN+P + V E+ T ++++ A D D +N ++E+ ISS PE F++ N G + V LD E + +L+V +D R S V + + D+NDN+P F R +A E+ G +VA D DS N V L F+L TV ++ ++ DRE + ++ D+G P T++ +++V V D ND AP F + Y + ED PGT + ++A D DEG N L Y I D F ++ + G + + LDRE S RA D G P + TA++ V + D+ND P S Y +T P++ + V D+ L S +VT + FS+ PDG + + S LDRE ++ ++I ATD
Sbjct: 1563 FVVDAASGVLRASRRLDREERASYL--------------LTVRASDGTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALN--------VTRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISS-GDPE--GRFAV-GNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPA--FTSPR---SALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALN------TVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENTQGPPVLILQVVARDDDLGSSGQVTYAAAGGN----------------------DGGAFSVSPDGHVHLLRS-LDREAQPQHVLIITATD 2133 HSP 8 Score: 165.236 bits (417), Expect = 2.580e-41 Identity = 161/605 (26.61%), Postives = 273/605 (45.12%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNP-SFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN---AKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEF-SLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
DRE+I Y + A D G P + + + ++V V D ND++P F + Y +++E + + V + A+DADS +N K+ Y I S + FS++ ++G + ++D E +++ L + A D G + + ++ + + D+ND EP FT A EN PG V S D D ENG V + +P ++ + R++ ++ K++TLKS DRE+ + + D G+P ++ V+V V D+ND P F Y + E+ GT + T+ ATD D G N + Y + DA F +N + G V LDRE A D G+ + S A +T+ V D D P + Y +V+ + A LV +V+ + LN+ T LI D+ FS+ G I + +DRE Y++ + A G +++ ++ V DVN+ P F S S + +P + + A D+D GKN E++Y N + F + P+ G++ ++ + + Y L V D G+ L + + + + +N
Sbjct: 299 DRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGW---FSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVND-------EPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLD---SLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVG-SVSASTLDLNANV---------TYLIVSGDQ---------------RGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGGVAGEASVSVL---VHDVNNHAPVFDRASYEVSIAEDEP---VNSRFFSVRATDKDSGKNGEVKYEIGEGNG-GEKFGIFPD-GQLYVRYELDRETR-EEYSLTVSAMDTGVEPLSSSVTVNVTVLDVN 856 HSP 9 Score: 157.918 bits (398), Expect = 4.075e-39 Identity = 201/784 (25.64%), Postives = 329/784 (41.96%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDD-----FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISP--EITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIP---LTV---MYKISTLKSFDREQKSKV-TAHIVCFDEGNP---RQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVE---SLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-----VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEY--PIQKLFR---DVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
++ EK V FE++ G I R DR+ L ++ + ++ + D + + V+D+NDN P ++++ SE + A D D G NG Y+I+ E +F + T++ S LDRE+ Y +V+A D G S V V V DENDN P F +++ + E+ + +I L A D D+ +G + Y I + F+I+ ++G + + LD+ET L V A D G R S +++++RD NDN P F P A I EN G V + +D D++ NG++ +S+ R P T+ +I T DRE + + D+ P R++ +V+V V D ND AP F + I G+ + T+ A+D DE NA + Y++ G DA I F +++ G + T+LDRES +L A + P+ N T+I + N P LP+ Y +L+ T +P + + L+ E + LV T + R P+ +R D+T +FS L +R++G + PP S+ + I+V DVND P F P ++V+ T G I + A D D+G+N+ + YS S ++ F+++ SG + + + + Y+L V D ARL + + N +S
Sbjct: 899 YSFEKPQVNFELDSETGRIASLRVFDREALI--------RQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGS------------LDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNT---HATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPA--FLPGDVF--ASIMENIPIGTRVITVTARDPDADVNGEL----------HYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAAAGSVVGTLQASDPDEAENAAVRYAVTGGDAAILFRLDRRTGIIETSTELDRESGHGAFTLEVVAVEAKAAAPRTQRAEN-TIIANSMTFNHP-LPRFPQDYESPINLLQGQTIPMPSSYLFLR---HHLDWEPEGQLVFFTLLLGVTRGHGVINPLDAPWRVSFDLTARCMFIVFSSLLSS---LRDNGAGSFI--------------RPPMSSFNQVEISVEDVNDNPPVFAVP---EMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSE--GAFVVDAASGVLRASRRLDREER-ASYLLTVRASDG---THATDARLSVAVRDANDNS 1614 HSP 10 Score: 124.405 bits (311), Expect = 7.949e-29 Identity = 101/367 (27.52%), Postives = 160/367 (43.60%), Query Frame = 3
Query: 1545 PRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKS----FSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNG---IPRLEDTARLRIIIESIN 2621
P ++ V + VED+ND P F+ V E+ G +FT++ATD D+G NAL++YS+ F ++ G + LDRE S T RA+D + A ++V V+D NDN P + Y + V E+ D T+ + T L D P ++ + S +++ F L P + LDRE Y + ATD G + + +Y+NVLD ND P + +V GT++ +I A D+DEG N+ELE+S S + + N G++S+ + + + Y L+V V D RL R+ +I+ +N
Sbjct: 1494 PPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDG---THATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPD---------------GKTTRAVI----GTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATAR--LYVNVLDANDNAPSV---QNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGN--DGQLSVARALDRERQ-SFYNLVVRVSDRARHPPARLSSAVRVSLILTDVN 1830 HSP 11 Score: 92.0485 bits (227), Expect = 6.545e-19 Identity = 87/367 (23.71%), Postives = 135/367 (36.78%), Query Frame = 3
Query: 1569 VSVGVEDINDEAPHFSEKSYI-FHVNEDVKPGTYLFTINATDKDEGINAL--LSYSIFG--KDAKIFSINKLDGKVFLE----TDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSL-FSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKP--KFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDE-GKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQE--SHKVCCYVLIVVVKDNGIPRLED-TARLRIIIESIN 2621
V V V D+ND AP F E + ED G + A D+D G N + +Y I ++ ++ + + FL LDRE+ S +A D G P++ + V V+D NDN P K Y + ++ P+ RD+ L P ++ LD E +Y + + A D GNPP S + I +LDVND P +F++ + + V GT A + D D N EL S N+ L P + + + + ++ Y L ++ DNG P TA L + + +N
Sbjct: 9 VRVVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASV----------------------------------------AEDSPVGAALRDLLHRGRGPLAVPFDPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVN 335
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 263.462 bits (672), Expect = 6.793e-72 Identity = 215/694 (30.98%), Postives = 325/694 (46.83%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVT-CHLEPIANEEFSLE-RMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
+ I ++DINDNSP + Q V + SE S G A D D +NG Y++S F INT+T + + K QL D EK +Y V A DGG PS + V V V D NDN P F K++Y +V ENL + V + A DADS NGKI Y I S + F+++ +G I R LD ET + SL + A+D +R + TV I+I D NDN P + PSRF I+E+ G V + D+D NG VT + F L+ R I +S + DRE T + D G+P+Q+ + S+ V V D+ND AP F + + + ED + + + DKDEG N ++ S+ G+ + F+I+ G V +T LD E+ + T A D G P + +TA + + + ++NDN P F+ + + E+ + +V++N TD+D L D+ + + S F + LI LDRE T Y +V+ AT+ G+ +S I VLDVND P F S + S + P G T+A++ A D DEG+N+++ Y + + F +NP +G ++ ++ + + Y L V D+G P A + + I +N +S
Sbjct: 569 VTIALQDINDNSPIF-QGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFS----INTSTGLITLKTQL--------DYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNE---NMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQP-TFTGPSRF----NISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRSGI-------LSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTIDST-GFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDG---------------------------TPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPI---GQTVAKVTATDRDEGENAKVTYELSVGDTSK--FEVNPATGLVTTKRPLDREDQ-ASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNS 1200 HSP 2 Score: 241.891 bits (616), Expect = 5.100e-65 Identity = 213/760 (28.03%), Postives = 349/760 (45.92%), Query Frame = 3
Query: 357 YKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKS-FDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKF---IFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
Y F N + F ++ + GV+T+ R +D + + + L +T + + L+I V DINDN P +S + ++ E + G S T D D TNG + I + + I+ +T + S + K D E +Y+ V A D G P + +V + + D ND+SPVF + Y + E+ + V+ + A D DS G++EY+ L F+I++NSG I V ELD ET + SL VEA D G+ R S+ V I ++D+NDNSP I+ P F +++E+ +PG + + D D + NG V L + FS+ + TLK+ D E+K++ + D G P +++ V V V+D+ND P F++ Y V E++ G + + ATD D G N +SYSI G + F++++ G++ LDRE++ S T A D + ++ + + + D NDN P + E+ + Q+ TD D G N ++S + NS F L P ++ S LDRE Y +V++A+D G+P +S I+++VLDVND P+F +F SG +++ +T+ Q+ D+DEG N + S + + +D F + +S L +T + Y L V +D G P TA+++I I ++N
Sbjct: 308 YSFTSGNTNHA---FTLDAVTGVVTVSRSLDFEQ----------RSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVSAT---DRDSSTNGALVFGIIKG--NDDGVFTIDGSTGIIS--------IAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYR---LISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSP-IFQGPYVF----RVSESSSPGHQIGQVAATDADDSSNGDVRYALSD-NTDVFSIN-------TSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIIS-----------------------GNQGNS-FQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLF-SG-----EIREDASVHSTVLQVKVEDKDEGSNGAITLSL--SGEGSDNFTI--DSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVN 991 HSP 3 Score: 232.261 bits (591), Expect = 5.063e-62 Identity = 190/687 (27.66%), Postives = 315/687 (45.85%), Query Frame = 3
Query: 555 VLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSY-IINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
V +I V D+NDN+PF++ + T E +G A+D D G N LSY +++ +T ++ Q + K DRE Y+ + A DGG+PS +G V + + D NDN PVF A Y SV+E++ ++ + A D D+ N + Y S T F++++ +G + V LD+E ++ +L + D G+ T ++IN+ D+NDN P F PS + +++ EN G V S D+DS+ NG + + I + + ++ + IS KS D E K++ + D G P + + V++ +ED+ND +P FS +Y + E G+ + T+ ATD D G L Y + + K F+I+ G + + ++LDRE+ S A D G + S+ +T+ ++DINDN P V E+ + + QV TDAD+ N + + L T +FS+ LI ++ LD E T+Y + + A D G P +S+ ++ + V DVND P+F + S T V +G + + A D D G N ++ YS S N+ N F M+ +G+I+ + + + + Y L + D + R + I I
Sbjct: 153 VPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINA-------------RLSYSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRY---SFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPP--VFSPSAY--QSRVKENTPAGTQV---SATDRDSSTNGALVFGI--IKGNDDGVFTIDGSTGI---ISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNT--------------------------DVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQF---AKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNE-NMAFAMDRFTGEITTRVPL-DRETIASYSLTINADDGSLVRFMAATTVNISI 780 HSP 4 Score: 226.868 bits (577), Expect = 2.673e-60 Identity = 206/746 (27.61%), Postives = 330/746 (44.24%), Query Frame = 3
Query: 399 FEINPLNGVITIE-RRIDRDNLCHLVPTCCPK-KNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPI-ANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
F I+ G IT R+ DR++ T + N+C+ T V+VI+VKD NDN+P + N V E + ++ A D D GTN YS+ +F MM N + ++ LD E D Y ++AFDG + +F ++ V D NDN+P F +VY V E++ + V QL A+D D +N ++ Y + S F+++S G I + D ET + + + A D G+ R TV I I D+NDN P F +++T A + E+ A G + + DKD+ N + N F+L+ + +TV +S D EQ+S + D G+P T + + + V DIND P FS +Y V E+ GT ++ATD+D N L + I G D +F+I+ G + + D E+ T +A D G P + TA +T+ ++D+ND+ P F P + + E+ +V V TD D G + L+S F++ + I S LDRE T Y + +EA D G+ +S+ + I + D+ND P F P +V + G I Q+ A D D+ N ++ Y+ N D+F +N +G I+L+ + + K Y++ V KD G P ++++++ +N
Sbjct: 12 FTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRT-----------VVVIDVKDENDNAPEFPLNSYVFNIRENTPAA-QVAIVTATDRDSGTNAAITYSLFSGENKF----------MM--NSKTGEIRTVTPLDHETKDSYTMRISAFDGKHTTF----VPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVS----GDTSYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRP--VFSSAQYT--ASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVS------RSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQ---VSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNV------------------------KGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGP----YVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDN---TDVFSINTSTGLITLKTQL-DYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVN 679 HSP 5 Score: 216.083 bits (549), Expect = 7.416e-57 Identity = 212/807 (26.27%), Postives = 362/807 (44.86%), Query Frame = 3
Query: 225 NHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDF----SHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGD 2627
N + ++E LP +G K TD ++ ++ K Y+ + K FE+NP G++T +R +DR++ Q + L + + D S + + + + D+NDNSP +SQ++ +E + G + +A D D G NG YSI N + ++ + +DRE + Y ++A D G P + + V + V DENDNSP+F ++E + + V + A D D N ++ Y S+ + + + F+I + +G + V+ E++ ET T +L + A+D G+ S + + + D+NDN P F + + + EN A + +V +V DS+ I+ + ++N V I T D E+KS+ + D + T +V++ V ++ND P F++++Y V E+ T + ++A+D+D LSYSI GKD+ FSI++ G + LDRE V R D+G P + +T+ + D NDN P F S +LEN ++ TDADEG N+ ++T Y + + N F + +I LDRE + Y++ I+A D G PP+++ I + V+D+ND +P S S + +P+ T + +I+A D D G N+EL +S SN + +F ++ +G IS + + + Y L + V D G P L A +II+ I+ D
Sbjct: 1100 NPGSYAKSLHENLP-------IGQTVAKVTATDRDEGEN-AKVTYELSVGDTSK----FEVNPATGLVTTKRPLDRED--------------QASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISG----------NHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFY---SIVRGDTSA-FAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPP--VFNSQSYIGSVR--ENSA--QSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGV---IMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDS--FGSLSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNA--RIT---------------YNLSR----------NDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKE---THVMRILASDADTGLNAELTFSLLSNEHKS-VFTLDNTTGDISTKVPLDREQQ-AVYTLRIGVADKGNPSLSSVA--DVIIDVIDED 1818 HSP 6 Score: 208.764 bits (530), Expect = 1.192e-54 Identity = 207/677 (30.58%), Postives = 305/677 (45.05%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDD----FSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINT-NTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIAN-EEFSL-ERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL-PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVK-PRTVSGTTIAQIIAIDED 2402
F I+ G IT+ +DR+ L + +LTI + D + + I V D NDNSP ++ NE EG IG ++ A D D G+N +YSI T ++ IN N ++ KE ++RE + Y + A D G+P ++ V V D NDN PVF YI SV EN +T V+ + A D+D N + Y I S K F I S SG I LD+E + L V A D + + V I + +LND +P F +T A + EN V S D+DS G ++ + + ++FS+ +R I IST DRE S + D GNP + V++ + D ND +P F SY + E+ P ++ F + ATD DEG NA ++Y++ DA F I G + L LDRE+ + +A D G P Q S+ I V V DIND+ P + S+ V EN + ++++ +DAD GLN+E +L+S +E+ S+F+L I + LDRE Y + I D+GNP S+ + I+V+D +D P+F P+ N T+ PR G +I Q+ A D D
Sbjct: 1251 FRIDSTTGRITVVGVVDREALA--------------SYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTS---AFAINAMNGVLTVKKE---------INRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGND---EKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPA--FTQQNYT--ASVRENSPTSTSVVKVSASDRDSF--GSLSYSIVGGKDSDKFSIDQRSGI-------ISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRNDA--FMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLS----------NEH--------------KSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRF-QPTEYNVTISESLPR---GASIVQVTARDID 1852 HSP 7 Score: 204.527 bits (519), Expect = 2.458e-53 Identity = 172/597 (28.81%), Postives = 279/597 (46.73%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYL-YVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
DRE Y +V A + G+ + + V D NDN+PVF Y S++ENL V ++ A D D N K+ Y++S + F + +G + + LD E + SL V A D G + + + + I DLNDNSP+ F S++T +TEN A G + D D+ NG+VT + I+ + R++ + +I+ + DRE + I D G P ++ V++ V D ND +P F+ + ++E V G+ + + ATD+DEG NA + YSI D F+IN ++G + ++ +++RE+V + T RA+D G P S +TV+V D+NDN P Y+ V EN ++ V D+D G N+ + +++S DE K F+ S S + + P LD E ++Y + + ATD K+ + I V+++ND P F + N T V+ + + T++ ++ A D D L YS + +D F ++ SG IS + + V Y + V V D G P L + + I I
Sbjct: 1058 DRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSK----FEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQ--FSQSKYT--LTVTENTANGSNILRVLASDPDAGANGRVTYSI--ISGNHGNAFRID---STTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISG--------NDE----KRFK--INSTSGVIMTTTP----------LDFEEKSQYGLEVTATDSKYTAKTN---VTIRVINLNDITPAF---TQQNYTASVRENSPTSTSVVKVSASDRD--SFGSLSYSIV-GGKDSDKFSIDQRSGIISTADVL-DRELVSLYAIQVRVTDAGNPPLSNLTWVTIKI 1607 HSP 8 Score: 193.356 bits (490), Expect = 7.853e-50 Identity = 176/608 (28.95%), Postives = 266/608 (43.75%), Query Frame = 3
Query: 822 DREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLK---AIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
DRE +Y V A D N G V++ V DENDN+P F Y+ N++ NTP Q+ A D DS N I Y + S F + S +G I LD+ET + ++ + A D + +T +I + D+NDN+P +F S + + E+ A G +V + D D N +++ L F+++ + I T +FDRE K+ + D G+P ++ +V + + D+ND P FS Y V+EDV G + T+ A+DKD G NA L YS G F+++ + G V + LD E S D G P T+++ + V DINDN P F P + V EN A QV+ TD D N L + K + +F++ +I D E T+Y++ ++A DRG P K + I + DVND P F S SN + ++ TV G+T+ + A D D G LEY S N F ++ SG I + + + Y L V +D G + R+ I ++ IN +S
Sbjct: 29 DRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVF----NIRENTPAAQVAIVTATDRDSGTNAAITYSLFS-----GENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDG----KHTTFVPLITVDDVNDNAP--FFALSVY--KTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGV-------IRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAG---TQVSATDRDSSTNG------------------------ALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVF---SPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGN-VKGAFNIDANSGSIRVSSEL-DRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNS 580 HSP 9 Score: 179.874 bits (455), Expect = 1.350e-45 Identity = 156/524 (29.77%), Postives = 237/524 (45.23%), Query Frame = 3
Query: 1095 LFSIESNSGYIHVRW-ELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTA-DVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS-ILSKENKMK 2657
+F+I+S++G I + D E+ + L V A D N V+I+++D NDN+PE F I EN P VA+ + D+DS N +T L FS E + + +I T+ D E K T I FD + TT + + V+D+ND AP F+ Y V EDV G+ + + A D D GINA LSYS+ D F+++ G + + DRE+ S RA D G P + A + + + D+NDN P + Y ++ A +V V +D D G N++ + + T +N F+L ++ LD E + Y + + TDRG+PP + + INV D+ND P F PS S +VK T +GT Q+ A D D N L + N + +F ++ +G IS+ ++ +K Y L V +D G+P DTA++ I IE +N S + S N K
Sbjct: 11 MFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVF----NIREN-TPAAQVAIVTATDRDSGTNAAITYSL-------FSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDG---KHTTFVPL-ITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDS-QGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSF------------------------TSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVF-SPSAYQS--RVKENTPAGT---QVSATDRDSSTNGALVFGIIKGND-DGVFTIDGSTGIISIAKSPDYENK-TRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSK 485
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 244.202 bits (622), Expect = 7.744e-66 Identity = 216/751 (28.76%), Postives = 336/751 (44.74%), Query Frame = 3
Query: 381 EKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISP--EITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPE--IYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE-FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGK-DAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVL-ENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKV-CCYVLIVVVKDNGIPRLEDTARLRIII 2609
E S F N GVI+ RIDR+ + L +++ + + I + ++V DINDN P + + E ++ + + A D D G NG Y+I+ F L T L ++ KK LDRE D Y+ + A D G P+ G + + + DEND++PVF + Y+ S+ EN + ++++ A D DS NG I+Y I + +F ++S++G I + LD+E + + V A+D G + TV IN+ D NDNSP+ I + P + A +EN +A V DKDSN N + + +E F +E + Y I K DRE + D+G P ++T G V + V D+ND +P F+ +Y +++E + G+Y+ +NATD DEG N +SYSI G D F ++ G V LDRE V S+ T A D G + + +TV + D NDN P KS Y + E + ++QV+ TD D G N + S A N LF L ++ +S LDRE + Y + A D G+P + + + + D+ND P F S ++ +P + Q+ A D DEG N+ + Y N N F ++ +G IS ++ H+V + LI+ KD G TA + + +
Sbjct: 36 EGSPKQFGFNSNTGVISTTARIDRETTTQI--------------SLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLG------TTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI-DWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLG-----FYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQV----------------------NGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPP----GKLLQVTATDADEGTNAVISYDIIGGNN-NGNFSIDSSTGVISTLASLD--HEVEEFFSLIISAKDGGNKYAAKTAVVNVTV 731 HSP 2 Score: 213.772 bits (543), Expect = 2.879e-56 Identity = 200/713 (28.05%), Postives = 324/713 (45.44%), Query Frame = 3
Query: 501 QCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVN-------ENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGY-IHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI---FSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRI 2603
Q N+ T + ++ I + D ND++P ++QN + +E ++ G S A D D G+NG Y+I + + + ++++T + K+ L D E + Y F V A DGG PS N V + V D NDNSP K Y+ N EN NT + + D DS N + E +I T + F +E Y I ++ LD E +L + D G R + V+I++ D+NDNSP F + +T A I+E G V + D D +NG V+ + + +++ + ++T K DREQ S VT I D G+ +T S +V+V + D ND P F + SY ++E G + ++ATD D G N ++Y I DA++ F +N G ++ ++ LDRE+ FT A D G P+ +S+ + + + DINDN P F P + ++EN L+QV TDADEG N+ + D+ +N FS+ +I + LD EV + ++I A D GN + ++ + VL+ D P F++ + + + P+ GT + ++ A +D KN + Y+ S + TN LFL++ G I + + K Y+L V+ + + L A + I
Sbjct: 173 QLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNL--------DFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQL-KITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKI---TNGDDEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPA--FTSNAYT--ANISELAQNGSYVLQLNATDPDEGDNGTVSYSIT--GGNDLGWFQVDFQSGL---VTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPG-KLLQVTATDADEGTNA------------------------VISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPK---GTLVGRVYATTKD--KNGSISYAIVSGDPTN-LFLVDSTGGIIKINGDMDREEK-AQYLLAVIARVGTVKPLSAQATVNI 832 HSP 3 Score: 209.149 bits (531), Expect = 9.733e-55 Identity = 214/740 (28.92%), Postives = 337/740 (45.54%), Query Frame = 3
Query: 426 ITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISP--EITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIA---NEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKD-AKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLST-ANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
I +++ +DR+ LVP L++T K S + ++I+V D+NDNSP ++ N SE ++ G A D D G NG YSI+ ++ F++ + + + K LDRE++ + A D G+ GS V V + D NDN P F K+ Y +++E V+Q+ A D DS NG+I Y+ISS + + LF + + +G + + +LD ET + S V A D G+ + S+ V + I D+NDN+P Y P + A I ENE PGKL+ V + D D N ++ + I N FS++ + ISTL S D E + + I D GN + V+V V + D P F + Y F V E+V GT + + AT KD+ N +SY+I D +F ++ G + + D+DRE ++ + A G K LS A + + V D NDN P F S+ + + + D D G N + L S A L+ + KL R +T DG T+Y + + A+D G+PP+ + I+I L +N PKF S + +P + ++A+D+D GKN +L YS N+ LF + P GK+ +++++ ++ K Y LIV D G+P + + I I+ N
Sbjct: 377 IQLQKPLDRE----LVPFY------NLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDF------------QSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISS-SDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFY--PVEYF--ASIMENEPPGKLLQV-TATDADEGTNAVISYDI--IGGNNNGNFSID------SSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDREE-KAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSN-AEGLLWINSTSGVIKLARKLT------------DGD------------ETQYTVQVLASDSGSPPQHSTMTIHI-TLSINH-PPKFTLSSYVTHVLASQPLSYQ---FFYVVAVDQDSGKNGQLFYSIPQGNE-EGLFGIFP-GGKLYIRKSLLQALK-GSYDLIVRATDGGVPSFSASVPVTIYIQDSN 1044 HSP 4 Score: 193.356 bits (490), Expect = 6.770e-50 Identity = 187/648 (28.86%), Postives = 287/648 (44.29%), Query Frame = 3
Query: 669 VALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYE-----TYTTISLIVEANDMGN---LRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL-EPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLP-KSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTT--IAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIP 2573
VA+D D G NG +YSI P+ E L + I +Y K L+ + Y+ IV A DGG PSF+ S+ V + + D ND+ +F + +V EN T V L A D I Y SL E F+++ SG I R LD E T + + I++A M N ++R VI+ + DLNDN+P SR ++E PG V D D +N K L ++F + L + K+ DRE S + D N ++ + + V D ND+ P F E Y ++ ED G+ + +NA+DKD G N L+ YSI G A +F + G++ + LD E+ + T A D G ST N+TV V D+NDN P P + + L V EN P+ + +D D G N+ ++ S+T + + + ++T + L +P G R+S +++V+ ATD+G+P ST+ I + V D ND P F+ P P +G++ + I A D D N ++ YS S N N F ++P +G++ + I ++ + Y L + D G P
Sbjct: 969 VAVDQDSGKNGQLFYSI-PQGNEEGL-FGIFPGGKLYIRKSLLQALK---------GSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVY---SLISSE--SHFAVDVRSGQITTRVRLDREELIKNTGSNV-YIMQAEAMYNDTTIKR-DKAIVIVTVTDLNDNAPVF----SRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLS------KTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPS------KTFSVNSATCEITTIAAIDL-ETMPAG----RDS---------FQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSP----------PAAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGN--NGYFNLHPSTGQLQMIHQIPDNPTI--YQLTIQASDGGQP 1554 HSP 5 Score: 186.422 bits (472), Expect = 1.201e-47 Identity = 188/707 (26.59%), Postives = 299/707 (42.29%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFI-----FPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQ 2501
+F+++ +G++T + +DR+ + + T + + + + + + D NDN P + ++ SEG+ IG + A D D G NG Y IS + + +NT T + K QL DRE Y F V A D G+P S+KV + ++D NDN+PVF Y S+ EN + ++Q+ A DAD N I Y I FSI+S++G I LD+E SLI+ A D GN T V + + + DN P +E FT + EN G LV KD +NG ++ + ++ + +L ++ ++ KI+ DRE+K++ ++ + +V++ V D ND AP FS S I ++ G ++ A D D G N L+ Y + + IN G + L L A+DSG P Q ST I + + IN F S +VL + V D D G N + LF + + LF + P GKL IR+S L + + Y++++ ATD G P S + I + D ND + F+ F NS+ P T+ GT +A + D + ++ YS S+ F ++ SG+I+ +
Sbjct: 472 WFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSA----------PKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQL--------DRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMEN-EPPGKLLQVTATDADEGTNAVISYDI---IGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFT----VYENVPKGTLVGRVYATTKD--KNGSISYAI--VSGDPTNLFLVDSTGGII-KIN--GDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLS-INHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQ------------------------LFYSIPQGNEEGLFGIFPGGKLYIRKS-LLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSS----PGTLVGTLVAHAL----DHSRTKDIVYSLISSESH---FAVDVRSGQITTR 1108 HSP 6 Score: 167.933 bits (424), Expect = 6.202e-42 Identity = 203/747 (27.18%), Postives = 316/747 (42.30%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNA---KITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANE-EFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCF--DEGNPRQTT----SGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPD-----GKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQ-ESHKVC--CYVLIVVVKDNGIPRL 2579
F ++ G+I I +DR+ + + T+K S + IEV D NDN+P +S + ++ +G A+D D G NG+ Y ++ N +++ N + L +KL +Y V A D G+P + ++ + +T ++ P F + Y+ V + + + A+D DS NG++ Y I + +F G +++R L + LIV A D G ++ V I I+D ND+ S F NN + EN +PG LV D + + L I++E F+++ + +I+T DRE+ K T V E TT V V V D+ND AP FS Y V+E PG+ +F I A D DEG NA YS+ G F IN G++ L LDRE+ S + +A D+ STA I + V D ND P P+S Y + + E+ ++ +N +D D G N LIK S SN + + D G+LI+ +S LD E T YE+ I A D G P S+ + +NVLDVND P +FP+ T+ V+ +G + + A D D G N+ + +S S + F +N + +I+ I E+ + L+V+ D G P+L
Sbjct: 787 FLVDSTGGIIKINGDMDREEKAQYLLAVIARVG-------TVKP---LSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTS-----------NAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTI--HITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFP----GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHR-------SLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSL--ISSESHFAVDVRS------GQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNG-------------LIKY---------------SISNGNLAAMFDVESATGRLIVAKS-LDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAP--LFPT-QPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSK-TFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKL 1458 HSP 7 Score: 166.777 bits (421), Expect = 1.250e-41 Identity = 169/589 (28.69%), Postives = 265/589 (44.99%), Query Frame = 3
Query: 903 VIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTL-------KSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKD-AKIFSINKLDGKVFLETDLDRESV----ESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFL--PKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPD-GKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLE-DTARLRIIIESIN 2621
VIV VTD NDN+PVF +AVY I+V+E +PV ++KA+DAD N K Y + S T + K F I S++G +H+ LD ET ++ +L+V+A D N ST + I + D ND P F S +T N ITE+ G LV + DKD +NG + ++S+ N L M+ + + KS D E I D G +++ +V+V V D+ND AP F + V E+V G + A+D+D G NA +++S++ + +K FS+N ++ +D E++ +S A D G PK + +ITV V D NDN P P + A L + +T D NS KVT Y I S +N F+L P G+L + D T Y++ I+A+D G P + T+ ++ + P F S ++ V V+GT++ ++A N +EY S++ F + +G + + I + L+V D P +A + I ++ +N
Sbjct: 1145 VIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMD--KFF-INSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRP--VFPESDYTVN--ITEDALIGSLVINLNASDKDIGQNGLI----------KYSISNGN--LAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPA--------AAAGSSLNVMTITAEDPDRNSNGKVT---------------YSI--------ISGNNGYFNLHPSTGQLQMIHQIPDNP--TIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTF---SSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGG-FEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 8 Score: 157.918 bits (398), Expect = 6.712e-39 Identity = 167/661 (25.26%), Postives = 282/661 (42.66%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNL----------DLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL-EPIANEEFSLERMNIPLTVMYKISTLKSFDREQ----KSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYL--FTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDL-DRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYL-YVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDRE-VTTKYEIVIEATDRGNP-PKSTKGIIYINVLDVN 2291
++ S +F ++ +G IT R+DR+ L KN N+ D TIK D ++++ V D+NDN+P +S+ SE S G A+D D G N +YS+ T + +I ++ ++ +K LDRE Y +V A D N + + K+ + V D ND PVF ++ Y +++ E+ + VI L A D D NG I+Y IS A +F +ES +G + V LD+ET L + A D G + ST V +N+ D+NDN+P +P T + EN G V + D+D+ N + + ++ FS+ + +I+T+ + D E + ++ D+G+P+ +T S++V V D ND +P F G+ L TI A D D N ++YSI + F+++ G++ + + D ++ L T +A+D G P + + ++V + P + Y V EN A +V V LN + L S++ S F ++ ++ G+DRE + + +V+ A D+ P +++ + I V DVN
Sbjct: 1087 YSLISSESHFAVDVRSGQITTRVRLDREELI---------KNTGSNVYIMQAEAMYNDTTIKRDK-----AIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSG-TGMDKFFINSSTGELHLSK---------TLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSIS---NGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLT----VRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVN------SATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPA-------AAAGSSLNVMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQIPDNPTIYQL--TIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDS------------------------SKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 9 Score: 95.1301 bits (235), Expect = 1.276e-19 Identity = 97/344 (28.20%), Postives = 142/344 (41.28%), Query Frame = 3
Query: 1614 SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAAD-SGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGK--LIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNN-QTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDS 2630
+ SY FHV E+ PGTY+ ++ EG K F N G + +DRE+ + R + S P ++ V V DINDN P P Y L + E+ + TD D G N T+ S D T +FS + P G +I + LDRE T Y++ I ATDRG P +I I +LD ND P F S S + T G +I ++ A D D G N +++Y+ + Q+N +F ++ +G I +Q + K Y V+ D G+P D A + I + N +S
Sbjct: 8 AGSSYTFHVQEEQPPGTYVGKVDGASAFEG------------SPKQFGFNSNTGVISTTARIDRETTTQISLQLRTLNPSNQP-----ISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIAS-------------------GDNTATFSLGT-TACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGS---IAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVK-NSYTFNVIASDGGVPSKNDLATVTINVLDTNDNS 310
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 241.891 bits (616), Expect = 6.652e-65 Identity = 223/763 (29.23%), Postives = 341/763 (44.69%), Query Frame = 3
Query: 387 SSVYFEINPLNGVITIERRIDRDNL-CHLVPTCCPKKNNQCNLDLTIKSDD----DFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI---SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTV---MYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDA--KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISL-----QQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESI 2618
S+ YF I+ + GVIT +R +DR+ L H +K++D + L I V D+NDN P + +N E IGD A D D G+NG Y I + + F + + T+M KKLDREK+ Y V A D GNP + ++ V + + D ND +P F K VY ++ E++ N V ++A D D NG++ ++I S + FSI +G + V+ +LDYE +L+V A D G + TV I + D+NDN+P+ F S F I EN A G+ DKD NG++T FS + ++P ++ IS + DRE+ K T I D+G P + + +++ + DIND P FS++ Y + E+ + GT + + A D D G ++ YSI + F IN G + L L+ + F+ A+D STA + V V D N + P F +S V E+ + ++ V TD D G N++ +S + TL+ FS+ +I LDRE Y + ATD G P K +YI++ DVND P F+ PS KV+ G + ++ A D D GKN+++ YSF SN F ++ G I ++TI E Y L VV D G P + + ++++I+E +
Sbjct: 67 SATYFSIDQITGVITTKRGLDREFLDRHF---------------FRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVM------------KKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNF---FSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQ--FVSSHF--QTMIPENYAVGQEFYRVQAYDKDHGTNGEIT----------FSFMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVV-YSIVSSSGHDRCFRINP-QGLITLSCTLNYNTKHVYVFSVSASDGMLS---STALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAK-----ISYSIATLVPE---------------------FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPS---YEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPE------YELTVVATDQGTPPGQASVKVKVILEDV 745 HSP 2 Score: 237.269 bits (604), Expect = 1.830e-63 Identity = 206/704 (29.26%), Postives = 326/704 (46.31%), Query Frame = 3
Query: 585 DNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYI-INTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEE---FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN-GDSILSK---ENKMKDNVE 2669
+N P +S+ + SE +E+G + A D D G+NG+ YS+SP +Y I+ T + + K LDRE +D++ F V A DGG PS G + + + V D NDN P+FE+ +Y + E+ V+ ++A DADS NG+++Y I L FSI SG + V +LD E T +L V+A D GN R +T TV I + D+ND +P+ S+ +A I E+ +LV D D NG+V E ++ + FS+ R+N + V K+ D E + D+G P +V + + D+ND AP F + + E+ G + + A DKD G N +++S D FSIN+ G + ++ +LDRE V F +A D G P + TA IT+ + DINDN P F + + + EN ++QV D D G P ++ V+ S + F + P G LI L+ Y + A+D S+ ++Y+NV D N P+F S S +VK GT++ ++A D D G N+++ YS + F ++ +G I ++ + KV Y V D+GIP+L+ + + I I +N D + K E K+++++
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKR--------GLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCI--LNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQF----SKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEV--FFEIVSGNDMNFFSINRINGEVRVKQKL------DYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDLP-FSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG------------------------PTNVVYSIVSSSGHDRCFRINPQG-LITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRRSYS---AEVKEDASLGTSVLTVLATDRDTGSNAKISYSIAT---LVPEFSVDETTGVIKTAGSL-DREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIR 660 HSP 3 Score: 191.815 bits (486), Expect = 2.775e-49 Identity = 188/719 (26.15%), Postives = 313/719 (43.53%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRD--NLCHLVPTCCPKKN----NQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF--GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHK 2525
+F IN +NG + +++++D + + +L+ T K NQ +D I + D+NDN+P + + T E +G A D D GTNG I+ + +L + IN NT S KE+L DREK+ K+ F + A D G P G+ ++ + + D NDN P F + Y S+ EN + T V+Q+KAID DS G S ++ + + F I G I + L+Y T V A+D G L ST V +N+ D N ++PE R + +A++ E+ + G V D+D+ N K++ + + EFS++ I T S DRE+ + D G P+ V + + D+ND P F + SY V ED++PG + ++A+D D G NA + YS G F+I+ G + LDRE++ T A D G P ++ + VI++D+ D+ P K +Y + V E+ P++ V K +D P + + + S +F + P+ I LD E ++Y + + AT P T+ + + + D+ND P + + V+ V +I A D D + +L + N + +N SG++S+ + + ++ K
Sbjct: 281 FFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVD----------------IALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNG----EITFSFMQNDLPFSINENTGGISIKEEL--------DREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDS---GPTNVVYSIVSSSGHDRCFRINPQ-GLITLSCTLNYNTKHVYVFSVSASD-GML--SSTALVYVNVTDSNTHAPEF----KRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLV-PEFSVDETT------GVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKA------------------------KSQDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRATLS---PFFTETTVMVYLKDINDNTPVL---EAFHMNINVQEGKVPPEARYKIPAYDPD--VSDKLTFKVMEGN-AKEWVTLNATSGELSVNKKLIQASK 920
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 234.958 bits (598), Expect = 1.177e-62 Identity = 200/682 (29.33%), Postives = 334/682 (48.97%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFW---SQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI-SPEITE-FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVI-INIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAK-----IFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNG 2567
+++ V+D+NDNSP + + +LV ++ D + +A+D+DFG+N Y+I S + F+L +T+ +Y+ + + +DRE++D Y ++A DGGNP+ +G +++ + V D NDN P F Y ++ EN+ T ++Q+ A D D N +I+Y I + + P+ +F I +G I LDYE + ++V+A D G+ + S+ ++ I + D+NDN+P I+ + + ++TEN G VA SV D DS +NG+V LE + FS+ + ++ L I+ +S DRE VC D+G+P +TT S + V D+ND AP F +Y V E+ T + +NA D+D G N+ L Y+I F+I+ G + TDLDRE + + T D G P ++ V + D NDN P+ +S Y + EN + P+VQ+ D D G NS ++++ N+ F L P L+ LD EV + Y + ATD G +S +++++ D+ND +P F S+ +V+ T G +I Q+ AID D K + + + N +++F ++ SG I+L + + + Y+L V D G
Sbjct: 44 VLVYVQDLNDNSPSFVRGTSAKLVVFENDK----DFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYA--DLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQ--AIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYT-LGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEG-GDGYFSM-KFDV-LNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTP--------------------------NTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDNQPVF---DPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGN-ADEVFSVD-GSGLITLAKLLDRETQ-DNYLLTVKAVDGG 679 HSP 2 Score: 232.646 bits (592), Expect = 5.877e-62 Identity = 200/691 (28.94%), Postives = 326/691 (47.18%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSIS--PEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPI-ANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
I V D+ND +P + ++ T+ E + + ++ A+D DFG+N Y+I+ E + + I+ ++ M + L DRE+I + V D G+P + + VIV +TD NDN P F ++ Y S+ EN S +PV+QL A D D N I Y I + P F ++ G + LD+E ++ + V A D G R TV +++ DLNDN P F+PS ++ + EN G+ + D+DS + +E A+E FS++ + I+ K DRE + + D G V++ V D+NDE P FS+ Y F + E + + + ++A +D+G NA + YSI G I IN G ++L++++D E + SL+ T +A D G P AN+T+ V DINDN P F SI + + E+ V+V DAD G+ +L+S T LF + + + SL L+ G Y + ++A D G+PP+S+ ++ + V+DVND P F + T V T + I +++A D D G+N + Y+F S T+ L N GKI ++ + + + Y L V+ D+G PR +A +++I++ +N
Sbjct: 377 INVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDL--------DREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTP-----FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDNQP--VFDPSSYS--VEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDGSGL-------ITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINST-GTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGT-------------LFNLDSNTGALSLTKLIDYGN-----------SARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVF---GNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGLRN--GGKIFIKSKL-DREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVN 1010 HSP 3 Score: 213.001 bits (541), Expect = 8.692e-56 Identity = 208/791 (26.30%), Postives = 348/791 (43.99%), Query Frame = 3
Query: 225 NHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI----SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNP-SFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGK-DAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDED-EGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQE--SHKVCCYVLIVVVKDNG 2567
N + ++E P + V+ L AQ D G+ ++ + F ++P G++T R +D + + + T+ + + D+NDN P + + ++ E + IG S A+D D I+ + I + E+ + S +I ++ DRE D Y V A DGG S N +I V + V D ND P+F KA Y ++ E+ Q+ + + + AI D N ++ Y IS K + I S +G ++++ E+D+E ++ L V+A D G V I + D+NDNSP+ F S ++ E+ G SV D DS G+V+ L F+L+ L+ ++ L + +S T + D G+P ++++ + + V D+ND +P F SY HV E P + + + ATD D G N +SY+ K D F + GK+F+++ LDRE +E + A D G P++ S+A++ VIV D+NDN P ++ Y +V EN L V+ +D+DEG N ++ A ++ ++ GK+ + LDRE Y I ATD G+ P+ K + + V DVNDC PKF S + +V V G+++ +IA D+D +G NS++ Y + + F +N +G ++L + +H+ ++L VV D G
Sbjct: 499 NQSSYNASLFENSPSGSPVVQLLAQD-----------PDIGE--NSLILYSILTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVH------------VSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDGSGLITLAKLL---------------DRETQDNYLLTVKAVDGGGQDSVNKAI-VNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSIS---KGNTDNIVLINS-TGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQ--FNSSSIL--VRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALS----LTKLIDYGNSARS-YTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGLRN-GGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQFIVDKQT-------------------------GKITTSQV-LDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKF---SKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKA---FSLNQVTGVLTLVSPLDREVTHR---HILHVVASDKG 1199 HSP 4 Score: 206.453 bits (524), Expect = 8.478e-54 Identity = 206/778 (26.48%), Postives = 327/778 (42.03%), Query Frame = 3
Query: 336 QDFGK-PIYKFQFFNCEKSSVY---FEINPLNGVITIERRIDRDNLCHLVPTC------CPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIP-LTVMYKISTL---KSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLD-RESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
QDFG + N +S Y F I+P +G+IT +DR+ + +V T P ++ C++ ++ + D NDN P+++Q+ E S G +A D D G N + YSI + NT + + + + + LD E Y F V A DGG S N ++ V ++TD NDN PVF+ + Y + EN + + QLKAID DS + I E +FS++ SG I + LD ET L V+A D G + V I + D+ND P F + + N I E+ ++ +D N +V +S+ + N + ++ TL D E+ + + D+G P +V++ V DIND +P F+ S + + ED G +T++ D D G+ +S+S+ +F+++ G + L +D S S +A D G P + STA + + V D+ND P Y +VLE D +++V TD D G N S+ T S F L GK+ I+ S LDRE +Y + + A D G P +S+ + + V DVND P F ++ VK T + + A D DEG N + Y F + F+++ ++GKI+ Q + K YV +V D G D ++ +I+ +N
Sbjct: 416 QDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSV----------------IVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI------------LTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHV--SLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADE---VFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPP--IFSKAEY--NFTIQEHSQALSVIGHVHAISRDKGTNAEVV----------YSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDT------------------------SKFGLRNGGKIFIK-SKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHF---QQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQ---FIVDKQTGKITTSQVLDREAK-ASYVFSIVATDGGSSPRVDKTQVTVIVRDVN 1113 HSP 5 Score: 182.956 bits (463), Expect = 1.699e-46 Identity = 210/755 (27.81%), Postives = 332/755 (43.97%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRD----NLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVI-VAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMG---NLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI-FGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKI----SLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
F +N + GV+T+ +DR+ ++ H+V K NQ I + I V D+NDN P + E IG + +A+D+D G NG Y I NT+ N+ + + LD E ++Y V+A D G S +++ + V D NDN P F+K I + EN+ NT V +KA D DS +N +I Y I S + + F I S +G I +D E + SL V A D R +T T+ I I+DLNDN+P+ SR N + E+E V + D D+ + G V + +FSL+ T + K+ + S D E + T HI D G+P T+ +V V D+ND P F+ +I V+E+ GT + + A D+D G NA L+YSI G + FSI+K G + + LDRE ++ T A YP ++S+ ++ + V D NDN P F+ + L V EN A + + + V D D G N+ K+ + ++ F++ + + LDRE Y++ ++A D P + I I + D ND P F S++ ++ P GT+I + A D+D G N + Y+ +N T ++ ++ +G + + +I++ + C + KD G +RI IE N
Sbjct: 1166 FSLNQVTGVLTLVSPLDREVTHRHILHVV--ASDKGGNQS-----------LETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNG----------NTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAH---FKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFV---SR--NLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLK----TGVLKL--IGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARL-IYTLTVQDLDYGNNT------------------------KVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTP---PGTSILNLTASDKDSGSNGNIVYTL--SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFC-----IAKDQGQDPKMAIVPVRIKIEDKN 1848 HSP 6 Score: 176.022 bits (445), Expect = 2.182e-44 Identity = 193/737 (26.19%), Postives = 319/737 (43.28%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLT--VALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKL----------------------------FSIESNSGYIHVRWELDYETYTT-ISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFE-PSRFTNNAKITENEAPGKLVAVFSVQDKDSN-ENGKVTCHLEPIANEEFSL-ERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI-FGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPF--LPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTT--KYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKI 2492
F ++P GVI++ D L + KN + +L T + + ++L I V D NDNSP + + ++ Q +E + + + A D D GTNG YSI + N + + ++ K LDRE ++ ++ D G P + + +V V VTD NDN P+F+ + +++ E+ ++ V + A D D E ++ Y + S + P A L + I++++G I R +D + I + V+A D G + + V I I + E FE PS F K+ EN G V V D + G+++ ++E + F + +R + IS K D E K + + D+ P + V + V D+NDE P F + Y+ +E + GT + ++A DKD G N + ++I G D F+I++ G + + LD E++++ H + RA D G P + ++T+ V D+NDN P +P + VLEN + L ++N TD D G N+ T++ T Q LF + FS L + + D E T +Y + I+ATD GNPP S+ I +NV D ++ P F + + V G + Q+ A D D G + + F N T++ MN +G I
Sbjct: 2008 FYVDPFTGVISVASA---DALDY-----ESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSI----------WTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDP-LSEVNIREDTRTGAVVTSVVATDTDKE--SRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIII------TREPKFELPSYF---GKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIE--NSNYFRIGQRSGV-------ISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTG------------QGLF--LIDKFSGWLTTNIT----------FDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSF---NRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFFVFY--NPTSNALKMNATTGII 2676 HSP 7 Score: 173.711 bits (439), Expect = 1.086e-43 Identity = 199/788 (25.25%), Postives = 336/788 (42.64%), Query Frame = 3
Query: 189 AFQLPENSFESSNHKHFTID-------IYEELPRKTKVI-------DLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSP-FWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNG-ISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCH-LEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISL 2498
++QL E +N T D IYE +P T V D G + W+ D + +F+IN G+I IDR+ + + + +Q D + L I ++D+NDN+P F S+N +T E + ALD D G G + Y +SP+ +F L ++ S LD E + +Y ++A D G+P V V D NDN P F + ++I +V+EN + T V+++ A D DS N ++ Y I S + + FSI+ +SG I LD E T L V A + R S+ +V IN+ D NDN P+ + P K+ EN +P +L+ +VQD D N KV + + F++ R ++ST DRE K+ + D P T ++++ +ED ND P F + Y ++E PGT + + A+DKD G N + Y++ ++SI+ G V+ + + +F A D G +++ + + ++D N++ P K+ Y +++ N +A + V TDAD ++ KVT +R S SLF + + + +G ++ + I A D G+PP GI+ I + ++ D P+F+ + + + V + + G+ I + A ++++ YS S N+ F ++P +G IS+
Sbjct: 1312 SYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTID------------------SQSPRAHFKINSETGLIQTTHPIDREEISEY--SLKVRATDQA-----FTEQDRLYNTATLKIIIQDLNDNAPKFVSRN--LTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIGS------------LDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDK---FSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPK-FISP---VVTLKVPEN-SPARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRS------TGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVT---------------------YRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFL--NQTPARVSIPENSKVGSYITTVRA---RASSDAQVTYSIISGNK-GRAFYVDPFTGVISV 2019 HSP 8 Score: 166.777 bits (421), Expect = 1.679e-41 Identity = 181/717 (25.24%), Postives = 307/717 (42.82%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNE--NGKVTCHLEPIANEE--FSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHF-SEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETD--LDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVP--LVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKF--------------------IFPSGSNS----TVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
I V D NDN P + + + E S +LTV D D+G N YSI T+ + +T + + K LDRE Y+ V A D P + + + + D+NDN PVF++++Y +++E T ++ L A D DS NG I Y +S+ T ++SI+S +G ++ + + A D G + + V I I D N+++P+ P I N + LV + + D D+++ NGKVT L+ N F +E + + T F + + +I+ D G+P G V + + +I D+ P F ++ + E+ K G+Y+ T+ A + A ++YSI G + F ++ G + + + LD ES ++ A G+ + + V D NDN P F P ++ + E+ A P +V+V TD D G N + ++ + + + I ++T + KL LDRE T +++VI TD G PPKST + + V D+ND P F + + ++ T +K + G I ++ A D+D G N++++YSF N + ++ ++G IS ++TI + + V D G+P +RIII
Sbjct: 1634 INVMDRNDNPPKFISPVVTLKVPENSPARLIYTLTVQ-DLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTK----------LDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTY----GVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYE----VHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVE------SNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSD---AQVTYSIISGNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV------FTIDSTTGEITTA------------KL------LDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIII 2298 HSP 9 Score: 151.369 bits (381), Expect = 9.490e-37 Identity = 195/701 (27.82%), Postives = 291/701 (41.51%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDF-GTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFD-GGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVI-INIRDLNDNSPEIYFEPSRFTNNAKIT---ENEAPGKLVAVFSVQDKDSNENGKVTCHLE---PIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEG---NPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYL-YVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
+ + V+D+ND SP +S+N+ +E +G S +A D+D G N Y I F L+ + T++ LDRE ++ V A D GGN S + + V D NDN PVF +V E L + V + A+D+D NGK+ Y+I F I +G I LD+E L V A DMG ++ ++ ++ I + D NDN P F N IT EN V D DS N ++ ++ P A+ + + E I T DRE+ S+ + + D+ R + ++ + ++D+ND AP F ++ + +V ED + +I A D D G + Y I D FS++ G + L LD E V A D G P S V+V D+NDN P + +++ V EN +V+V D D G N+E ++ S D++ I K LI+ S LDRE Y + + AT P + + + INV+D ND PKFI P T+KV P I + D D G N+++ YS S N T+ F + +G++S + K Y L V KD P A + I IE N
Sbjct: 1105 VTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSLNQVTGVLTLV------------SPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKI---VNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPT-------FDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETG--------LIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRN-LTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGV------EMDKFSIDK------------------HSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPV---VTLKV-PENSPARLIYTLTVQDLDYGNNTKVLYSIMSGN-TDGAFTIGRSTGELSTTTKLDRETK-ASYQLSVQAKDITPPYYTAFANITIFIEDQN 1744 HSP 10 Score: 105.916 bits (263), Expect = 6.100e-23 Identity = 98/357 (27.45%), Postives = 159/357 (44.54%), Query Frame = 3
Query: 345 GKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHI----IVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFE-KAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTT--ISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRF--TNNAKITENEAPGKLVAVFSVQDKDSNENGKV 1388
G P+ + + N E S+ YF I +GVI++ + +D + + L + + DD + + + I V D+ND P + Q+ + Q+SEG +G A D D G NG +++I + + + S+ I+ T + + LD E I + V A D G+P + + V + V D NDN PVF + V ENL N+ + ++ A D DS N ++ + + T LF I+ SG++ DYE SL ++A D GN S T+I+N+ D ++ P +F NAKI G V + D+DS + G+V
Sbjct: 2334 GLPLGRISY-NIENSN-YFRIGQRSGVISVNKPLDYETKRRFL--------------LVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAI--QSGDDKGSFAIDRKTGVIRTQRA--------LDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTG---QGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKI------GDFVGQVTATDRDSGDQGRV 2655 HSP 11 Score: 73.559 bits (179), Expect = 4.494e-13 Identity = 87/290 (30.00%), Postives = 139/290 (47.93%), Query Frame = 3
Query: 1773 GKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPK--SIYLYVLENHTADVPLVQ-VNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRES--GLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVS-GTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIP-RLEDTARLRIIIESIN 2621
G + +T LDRE V + + T S PK + + V V+D+NDN P + S L V EN D Q + D+D G NS T+VS + +F+ ++K ++ L D L++ S G+DRE Y + I A+D GNP + I V D ND KP+F S S + P + GT+I Q+ A D+D G N+E++YS ++++ +F ++P +G I + K Y+++V +D G +L +A +RI + +N
Sbjct: 12 GVITTKTVLDREKVSAYNLTI-VEFSTPPKSYT---VLVYVQDLNDNSPSFVRGTSAKLVVFEN---DKDFRQKLIAVDSDFGSNSTQSYTIVSGN------------VGNVFKLISKRDTDG--DLYAD--LVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTI----PENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAK-RSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVN 273
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO46418 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ21]) HSP 1 Score: 225.328 bits (573), Expect = 7.687e-60 Identity = 209/709 (29.48%), Postives = 327/709 (46.12%), Query Frame = 3
Query: 564 IEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEY--AKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVT-CHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIY-LYVLENHTADVPLVQVNVTDADEGLN-------SETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFS-------------LLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKF---IFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIP-RLEDTARLRI 2603
I + D ND+ P + + E E+G S A D D G+N YSI P+ F I+ T ++K L K + ++ + + N D GN S V + V D ++ PVF + VY+++V E++ + +IQL A ++ N I Y I P F I + G + LD++ + SL + A + + + + I + D+NDN PE F R+ ++EN G V S +D+DS ENG+VT ++ +++F L+ N L ++T + FDRE + + T + D G+P++TT V + + D ND P F EK Y V E G L ++A D+D G+NA +SY I G F +N+ G + L LDRE+V+ T A D Y + A + V V DINDN P KS Y + V EN A +V++ +D D G + S + +V + + DE I + ++ S S ++ D +I LDRE + Y+IV+ ATD G+PP+ K + + V D ND P+F +F K+ G+T+A + A D DEG N++L+YS + + F ++ +G+I L T+ K Y L V V+D+G+P DTA L +
Sbjct: 1139 IRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQNDYFA----IDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVAN--DNGNVSRKTVTLVRITVLDLGNDPPVFSQGVYVVTVREDIAIGSSLIQLSA---STKTNKLIYYSIVPGNVPSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSLTIRA-ETTDPPMSAFANLKIFLEDVNDNPPE--FVMPRY--QGHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDSDKFGLDE-NTGL-----VTTREEFDREAQGRYTLALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDGKYSGE---ATVNVYVLDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLMIVGDVNDNKPRFPDEPYIGHVMENLKAGASVMTMSAVDIDDPDVGNNAVMTDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKRVF------AAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKEERPFRIDETTGEIILALTLDYETK-RNYRLKVKVRDSGVPLSFSDTASLTV 1817 HSP 2 Score: 182.57 bits (462), Expect = 1.677e-46 Identity = 160/547 (29.25%), Postives = 246/547 (44.97%), Query Frame = 3
Query: 504 CNLDLTIKS---DDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL--------------EPIANEE----FSLERMNIPLTVMYK---------------------ISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSI--FGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLS-TANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDAD 2006
N LTI++ D S L I ++D+NDN P + SE + IG S A D D G NG YS + + ++ NT + + +E+ DRE +Y + A D G+P V + +TDENDN P+FE+ VY ISV E+ S ++++ A+D D +N ++ Y IS + F + G I + LD E L + A D + TV + + D+NDN+P+ FE S + N ++EN G LV D D E+GK + +P +E +E + +VM I T + DRE++S + D G+P Q V V V+D ND+ P F+++ + ++E G+ + T++ATD+DEG+NA L YS+ K+ + F I++ G++ L LD E+ + + DSG P S TA++TV V D ND P F P S V E+ L+++ VTD D
Sbjct: 1331 SNFSLTIRAETTDPPMSAFANLKIFLEDVNDNPPEFVMPRYQGHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDSDKFG--LDENTGLVTTREEF--------DREAQGRYTLALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYIS---EGNINGAFEVNREFGTIRLAGTLDRENVDHYKLTLTAKDG---KYSGEATVNVYVLDINDNNPK--FEKSHYRVN--VSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLMIVGDVNDNKPRFPDEPYIGHVMENLKAGASVMTMSAVDIDDPDVGNNAVMTDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRLEVTDPD 1857 HSP 3 Score: 167.548 bits (423), Expect = 8.132e-42 Identity = 193/780 (24.74%), Postives = 342/780 (43.85%), Query Frame = 3
Query: 345 GKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNL-CHLVPTCCPKKNNQCNLDLT-IKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHV----RWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAK----ITENEAPGKLVAVFSVQDKDSNENGKVTCHLE--PIANEEFSL-ERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFD------EGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKV------FLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
KPI ++ F ++P +G + + +D + + H +N + N D I S+ D I ++D+NDN P + + E + +G + A D D G NG +Y + + + ++ T + K L D E + F+V A D GNP+ NG+ +VIV +T+ NDN+P F +++Y + V E+ S+ V ++A D D N + Y I+S + F I + +G I + + EL YT + + A+D ++ S VI+ I+D+N++ P FT+ A + E++ P V D+D+ NG+V +E P A F++ ++ I ++TL+SFDRE+K I+ D G R V + + D ND P F K Y + ED + G + ++ATD D G NA L+YSI ++ F+I++ G V E + +S + F A D+G + + + + V D+ ++ P + +Y+ + A +L+ +A+T + Y I + +V S + F + ++ LD + T+ + + I A + +PP S + I + DVND P+F+ P + P G+++ Q+ A D D G+N + YSF ++ +D F ++ +G ++ ++ + Y L + +DNG P+ + III
Sbjct: 758 AKPIRNARYSIVSPLETKFRVDPYSGDVRVRSGLDYETVKTHRF--TAEARNTRDNTDYANIDSEADVK------IVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVESQF------FSVDPYTGWITTKRPL--------DFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVAEDAGSDQLVATVQATDKD---NDPVTYSIAS---GDNTTNFVINNKTGVIKLVSNRKPELIGPYYT---MNISASDGLHV---SQAMVIVAIQDVNNHKPV-------FTDCASYHPVVMEDDPPNTFVMQVHADDQDTGANGEVIYSIEKPPGALSYFAIDDKTGI-------VTTLQSFDREEKPVYQIRIIGRDGGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQN-DYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNVSRKTVTLVRITVLDLGNDPPVFSQGVYVVTVREDIA-------------------IGSSLIQLSASTKTNKLIYYSI--VPGNVPSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSLTIRA-ETTDPPMSAFANLKIFLEDVNDNPPEFVMPRYQGHVSENAP---IGSSVLQVSARDRDSGENGRVTYSF-VQDKDSDKFGLDENTGLVTTREEFDREAQ-GRYTLALKARDNGSPQKTTDTIVEIII 1461 HSP 4 Score: 153.295 bits (386), Expect = 2.114e-37 Identity = 174/681 (25.55%), Postives = 293/681 (43.02%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEA------NDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKIST-LKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF----GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEAT-DRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKD 2561
+++ V D N+N P + Q+ EGS IG A D D G+N Y S +I F + T T+ Y R K KY F V AFD G PS + V V++ +D+ PVF K+ Y + EN +++++A+ G++ Y L + F+++ +G + ++ LDYE + L + A +M L + TV+I + D+NDN+P F R I + G V + D+DS + V LE + F++ P T + K + L+ F+R+ + V + D P + ++ +G D+ND P F++ Y V E+++ G + A D D+G NA ++YSI + +FSI+ G + + LDRE + T +A D+G P+ A I +IV D+ND+ P F S ++ + N D + Q D D G N + +++ ++ + I + DG L LD ++TT I I+ T D G P +S+ I I + V P+F+ + + +P+ G + I A D + YS S N+ + F ++P G ++ + + ++ K Y +IV+ D
Sbjct: 1 VIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADVKYQSSNDI--FAVDETTGTITLQYQ------------ASRNK--KYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYY---LVGGDPQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPEL--PAEATVLITVTDINDNAPR--FAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENADSFPFTI----TPQTGVIKTTAELRHFERDFYAFV---VTATDSTPPFHKVTANIQLG--DVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQG------NKQGYFSINHI-----------------DGSLF-----LDEKLTTLEPIDIKVTRDMGQPERSSTADIRI-FIHVQAGPPQFLSSPFVGNVTENEPK---GAFVVHISAASLD-----PVMYSIVSGNEAGN-FRLHPGVGWLTTVRPL-DNEKQSRYKIIVMAMD 610 HSP 5 Score: 116.701 bits (291), Expect = 2.788e-26 Identity = 194/786 (24.68%), Postives = 314/786 (39.95%), Query Frame = 3
Query: 336 QDFGK-PIYKFQFFNCEKSSVYFEINPLNGVI--TIE-RRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKD--------SNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSE-KSYIFHVN--EDVKPGTYLFTINATDKDEGINALLSYSIFGKDA-KIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLP-DGKLIIRESGLDREVTTKYEIVIEA------TDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQ-ESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
QD G + K+ N + S F I P GVI T E R +RD +V S F H + I++ D+NDN P ++Q E + G A D D G N YS I FE S ++ + + L LDRE + ++ + A D G P +G ++++ V D ND++P F + + + N ++ V Q +A+D D NG + Y I K Y FSI G + + +L T I + V DMG R ST + I I + P+ P F N +TENE G V S D NE G H + ++T++ D E++S+ ++ D N + + V V V ++ND P F ++ I N +DV G+ + I+A D D + +LSY I + A + FS+N + V T + R+ F +D+G P ++ A V++ + P+ D+ S + + TL+ K PI+ + F + P G + +R SGLD E + EA TD N ++ + I + D+ND P+F S ++ + P GTT+ + A D D G N + Y +S F ++P +G I+ ++ + E++ + +VV +D+G P TAR+ + + ++N
Sbjct: 252 QDSGSHALVKYGLENAD--SFPFTITPQTGVIKTTAELRHFERDFYAFVVTAT--------------DSTPPF-HKVTANIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYS----IINFEDS---RSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGY---FSINHIDGSLFLDEKL--TTLEPIDIKV-TRDMGQPERSSTADIRIFIH-VQAGPPQFLSSP--FVGN--VTENEPKGAFVVHISAASLDPVMYSIVSGNEAGNFRLH------------------PGVGWLTTVRPLDNEKQSRYKIIVMAMDLKN--RVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDADR--SDILSYRIEDEKARRYFSVN--NEGVVTSTRVLRDLDSPYLFKVSVSDNGKPPMVAQAMARVVL------LKYQPQQ-----------------------DQQRTSIQESAALGTRVFTLLTAK---PIRNARYSIVSPLETK-FRVDPYSGDVRVR-SGLDYETVKTHRFTAEARNTRDNTDYAN--IDSEADVKIVLRDLNDNPPEFFELSYRDTLPESAP---VGTTVLSVTARDLDSGVNGQFHYFVESQ-----FFSVDPYTGWITTKRPLDFETNPTHSF--LVVAQDSGNPARNGTARVIVELTNVN 932 HSP 6 Score: 111.694 bits (278), Expect = 9.473e-25 Identity = 113/458 (24.67%), Postives = 196/458 (42.79%), Query Frame = 3
Query: 558 LVIEVKDINDNSPFWS--QNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDRE-KIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCH-LEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP 1919
++I V DINDN+P ++ + LVT + G + + A D D G++ + Y + N ++ ++ Q ++ R + D Y F+V A D P F+ + + + D NDN P+F + VY + V ENLQ + Q A D D N ++ Y I + LFSI +G + LD E + L ++A D G R ++I + D+ND++P F F + +I N P V D D NG V ++ FS+ ++ L + K++TL+ D + V D G P ++++ + + + + P F ++ +V E+ G ++ I+A D + +++S G +A F ++ G + LD E A D ++S + V V ++NDN P
Sbjct: 209 VLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLE------------NADSFPFTITPQTGVIKTTAELRHFERDFYAFVVTATDS-TPPFH-KVTANIQLGDVNDNPPLFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPR--FSSGSF--HVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIK---------VTRDMGQPERSSTADIRIFIH-VQAGPPQFLSSPFVGNVTENEPKGAFVVHISAASLDPVMYSIVS----GNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMD--LKNRVSKVEVIVNVLNVNDNKP 632 HSP 7 Score: 109.768 bits (273), Expect = 4.280e-24 Identity = 116/475 (24.42%), Postives = 209/475 (44.00%), Query Frame = 3
Query: 1227 VIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKI-FSINKLDGKVFLETDLDRESVESLHFTTRAADSGY----PKQLSTANITVIVKDINDNFP--FLPKS-IYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKS--NNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESIN 2621
VI+ + D N+N P F+ S + + E G + + +D DS N V +N+ F+++ +T+ Y+ S R +K T + FD+G P +++ +V V + +D P F + +Y + E+ + + A G L Y + G D + F++++L G++ L+ LD E V S RA + P+ + A + + V DINDN P +P+ + + + A + +V D D G ++ K L + D +P F++ P +I + L Y V+ ATD + P K I + DVND P F P V V+ G I Q A D D+G N+ + YS + ++++++LF ++P +G ++ T+ + + ++L + KD G+PR+ A++ II++ +N
Sbjct: 1 VIVRVLDGNNNDP--IFQQSSYW--VALPEGSPIGTELLRVTAEDLDSGSNADVKYQS---SNDIFAVDETTGTITLQYQAS------RNKKYSFT--VTAFDQGKPSRSSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVGGDPQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGL---------ENADSFP----------------FTITPQTGVIKTTAELRHFERDFYAFVVTATD--STPPFHKVTANIQLGDVNDNPPLFAQPV---YKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTL-DREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVN 429 HSP 8 Score: 101.293 bits (251), Expect = 1.720e-21 Identity = 102/364 (28.02%), Postives = 153/364 (42.03%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSIS--------------------PEITEFELSYIINTNTMMYSN--------------KEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMG-NLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSN-ENG 1382
FE+N G I + +DR+N+ H L LT K D +S + + V DINDN+P + ++ SE G A D D G +G Y IS P I + + M S + + ++ LDREK Y+ +V A DGG+P G +KV V V D ND P F K V+ ++E+ + V + A D D +N K++Y + K E + F I+ +G I + LDYET L V+ D G L T ++ + + D ND +P FEP ++ A + E+ G+ + V D DS+ +NG
Sbjct: 1519 FEVNREFGTIRLAGTLDRENVDHY------------KLTLTAK-DGKYSGEATVNVYVLDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLMIVGDVNDNKPRFPDEPYIGHVMENLKAGASVMTMSAVDIDDPDVGNNAVMTDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKEE--RPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPR--FEPLSYS--AVVREDVDIGERLLRLEVTDPDSDSQNG 1863
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 297.745 bits (761), Expect = 4.646e-84 Identity = 243/805 (30.19%), Postives = 373/805 (46.34%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITI-ERRIDRDNL--CHLVPTCCPKKNNQCNLDL---TIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITE---------------------------FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEP-SRF---TNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVM--------YKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII-ESINGDSILSKE 2645
F E S +F+I+ + G +T E+RIDR+ L C ++ N+C +D I + + + + DINDN+P + L E IG L A D DFG NGI Y + + E FEL T+ ++Q +L++K LDRE+ D YE + DGG+P + + V +TD NDN+P FEK+VY + EN +P++QLKA DAD +NG+IEY + T+ +L ++ ++G++ V +D E + + V A D G + TV++NI+D NDN P I R A + E+ +A+ V D+D ENG VTC + + + F L+ P + M Y + T D E + IV D G+P T++ S+ V V D ND P FS+ E+ PG + T+ ATD D G NA +SYS+ IFSI+ G + + T+LDRE E F A D G +A + V+V D NDN P F+ YV EN + P+ V V DAD+G N+E + + ++ ++ + ++FS L DRE T Y ++A D G+PP+S + + V+D ND P FP S+ T+ + P + T + +IA D D G N++L YS N LF ++ +G ISL +++ H + L+V V DNG P T + + + E+++ +I+ +
Sbjct: 62 FTLESGSEFFKIDNITGELTTNEKRIDREKLQQCQMI-----FDENECFIDFEVSVIGPAQSWVDLFEGKVIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTD-----GEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATE-SVRRLLRLDESTGWLSVLHRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTV--VGDVPFQLK----PASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSPVGMVTVIDADKGQNAEMGL----------------FIEEEEEIFSIENETGTIFSTL----------SFDREQKTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSSYTL-LPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFR-LFEIDGATGVISLMAKLEQKH-YGLHRLVVQVTDNGQPSQSTTTLVHVYVNETLSNSTIVETQ 820
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 297.745 bits (761), Expect = 1.511e-83 Identity = 243/805 (30.19%), Postives = 373/805 (46.34%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITI-ERRIDRDNL--CHLVPTCCPKKNNQCNLDL---TIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITE---------------------------FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEP-SRF---TNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVM--------YKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII-ESINGDSILSKE 2645
F E S +F+I+ + G +T E+RIDR+ L C ++ N+C +D I + + + + DINDN+P + L E IG L A D DFG NGI Y + + E FEL T+ ++Q +L++K LDRE+ D YE + DGG+P + + V +TD NDN+P FEK+VY + EN +P++QLKA DAD +NG+IEY + T+ +L ++ ++G++ V +D E + + V A D G + TV++NI+D NDN P I R A + E+ +A+ V D+D ENG VTC + + + F L+ P + M Y + T D E + IV D G+P T++ S+ V V D ND P FS+ E+ PG + T+ ATD D G NA +SYS+ IFSI+ G + + T+LDRE E F A D G +A + V+V D NDN P F+ YV EN + P+ V V DAD+G N+E + + ++ ++ + ++FS L DRE T Y ++A D G+PP+S + + V+D ND P FP S+ T+ + P + T + +IA D D G N++L YS N LF ++ +G ISL +++ H + L+V V DNG P T + + + E+++ +I+ +
Sbjct: 62 FTLESGSEFFKIDNITGELTTNEKRIDREKLQQCQMI-----FDENECFIDFEVSVIGPAQSWVDLFEGKVIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTD-----GEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATE-SVRRLLRLDESTGWLSVLHRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTV--VGDVPFQLK----PASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSPVGMVTVIDADKGQNAEMGL----------------FIEEEEEIFSIENETGTIFSTL----------SFDREQKTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSSYTL-LPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFR-LFEIDGATGVISLMAKLEQKH-YGLHRLVVQVTDNGQPSQSTTTLVHVYVNETLSNSTIVETQ 820
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 297.745 bits (761), Expect = 2.295e-83 Identity = 243/805 (30.19%), Postives = 373/805 (46.34%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITI-ERRIDRDNL--CHLVPTCCPKKNNQCNLDL---TIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITE---------------------------FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEP-SRF---TNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVM--------YKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII-ESINGDSILSKE 2645
F E S +F+I+ + G +T E+RIDR+ L C ++ N+C +D I + + + + DINDN+P + L E IG L A D DFG NGI Y + + E FEL T+ ++Q +L++K LDRE+ D YE + DGG+P + + V +TD NDN+P FEK+VY + EN +P++QLKA DAD +NG+IEY + T+ +L ++ ++G++ V +D E + + V A D G + TV++NI+D NDN P I R A + E+ +A+ V D+D ENG VTC + + + F L+ P + M Y + T D E + IV D G+P T++ S+ V V D ND P FS+ E+ PG + T+ ATD D G NA +SYS+ IFSI+ G + + T+LDRE E F A D G +A + V+V D NDN P F+ YV EN + P+ V V DAD+G N+E + + ++ ++ + ++FS L DRE T Y ++A D G+PP+S + + V+D ND P FP S+ T+ + P + T + +IA D D G N++L YS N LF ++ +G ISL +++ H + L+V V DNG P T + + + E+++ +I+ +
Sbjct: 62 FTLESGSEFFKIDNITGELTTNEKRIDREKLQQCQMI-----FDENECFIDFEVSVIGPAQSWVDLFEGKVIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTD-----GEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATE-SVRRLLRLDESTGWLSVLHRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTV--VGDVPFQLK----PASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSPVGMVTVIDADKGQNAEMGL----------------FIEEEEEIFSIENETGTIFSTL----------SFDREQKTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSSYTL-LPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFR-LFEIDGATGVISLMAKLEQKH-YGLHRLVVQVTDNGQPSQSTTTLVHVYVNETLSNSTIVETQ 820
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 297.745 bits (761), Expect = 2.435e-83 Identity = 243/805 (30.19%), Postives = 373/805 (46.34%), Query Frame = 3
Query: 372 FNCEKSSVYFEINPLNGVITI-ERRIDRDNL--CHLVPTCCPKKNNQCNLDL---TIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITE---------------------------FELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEP-SRF---TNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVM--------YKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII-ESINGDSILSKE 2645
F E S +F+I+ + G +T E+RIDR+ L C ++ N+C +D I + + + + DINDN+P + L E IG L A D DFG NGI Y + + E FEL T+ ++Q +L++K LDRE+ D YE + DGG+P + + V +TD NDN+P FEK+VY + EN +P++QLKA DAD +NG+IEY + T+ +L ++ ++G++ V +D E + + V A D G + TV++NI+D NDN P I R A + E+ +A+ V D+D ENG VTC + + + F L+ P + M Y + T D E + IV D G+P T++ S+ V V D ND P FS+ E+ PG + T+ ATD D G NA +SYS+ IFSI+ G + + T+LDRE E F A D G +A + V+V D NDN P F+ YV EN + P+ V V DAD+G N+E + + ++ ++ + ++FS L DRE T Y ++A D G+PP+S + + V+D ND P FP S+ T+ + P + T + +IA D D G N++L YS N LF ++ +G ISL +++ H + L+V V DNG P T + + + E+++ +I+ +
Sbjct: 66 FTLESGSEFFKIDNITGELTTNEKRIDREKLQQCQMI-----FDENECFIDFEVSVIGPAQSWVDLFEGKVIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTD-----GEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATE-SVRRLLRLDESTGWLSVLHRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTV--VGDVPFQLK----PASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSPVGMVTVIDADKGQNAEMGL----------------FIEEEEEIFSIENETGTIFSTL----------SFDREQKTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSSYTL-LPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFR-LFEIDGATGVISLMAKLEQKH-YGLHRLVVQVTDNGQPSQSTTTLVHVYVNETLSNSTIVETQ 824
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 294.278 bits (752), Expect = 3.972e-83 Identity = 246/780 (31.54%), Postives = 360/780 (46.15%), Query Frame = 3
Query: 339 DFGKPIYKFQFFNCEKSSVYFEINPLNGVI-TIERRIDRDNLCHLVPTCCPK--KNNQCNLDLTIKSDDDFSHI------IVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNN----AKITENEAPGKLVAVFSVQDKDSNENGKVTC--------HLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIF-GKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIII 2609
D G P + E S Y ++ G I T E IDR+ L C ++++C L+ + D I I +IEV DINDN+P +S L E + G S+ VA+D D G+NG++ Y++S + + + +++ ++++ LDREK D Y+ + DGG P S + + VTD+NDN+P FEK Y + EN V+Q++A DAD+ NG I+Y + + +L I+ ++G I+V+ +D E + V A D G + S V I+I+D NDN+P I + A I+E+ G VA+ V D+D EN VTC L P + +R Y + T D E+ IV D GNP +++ S+ V V DIND P FS + ED +PG + + ATD D G+NA L YSI A +F IN G++ + LDRE VE F AAD G P + TA + + V+D NDN P F+ V EN P+ V V+DAD+G NS+ VTL E N F + I+ DRE + Y ++A D G+PP+S+ + INVLD ND P P+ S+ T +KP + T + + A D D G N+EL Y+ N + LF ++ SG+I L Q HK + L+V V D G P TA + + +
Sbjct: 61 DLGLP-DSGHLYKLEVGSPYLRVDSKTGEIYTTEIPIDRETLSD-----CRNLFEDDKCFLEFEVSITDMVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALS---AGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASD-TVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKR-------KYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQ--VTLFVEP------------------------DNGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYT-HLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGN-PHGLFQISHNSGEIKLAQGFTGKHK-GLHRLVVRVSDKGKPPRHTTALVHVYV 794
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000074162.1 (SMESG000074162.1) HSP 1 Score: 2091.23 bits (5417), Expect = 0.000e+0 Identity = 1069/1077 (99.26%), Postives = 1075/1077 (99.81%), Query Frame = 3
Query: 108 MNYEEHENFALKFQRMQIIKIFVGFCFAFQLPENSFESSNHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKENKMKDNVEYSNEESDNFDFRXXXXXXXXXXXXXXXXXXXXMMSLATALLVCRKFKQDRNYSQRERFQLKQNFRIWKSNVKKSFINKRQQELNQVEPVSGQSLIQKNMNNEDRLQINSVNKSNHSYFLNPLTLEYNPNSSTIENKDLPINLQKYSTRQFGEFQNEILIPGVSTYFDYNHSSGETDNKKQNLEVMTXXXXXXXXXXXXXXXKNCAFPAQFQTFTPHFLSGCNV 3338
MNYEEHENFALKFQRMQIIKIFVGFCFAFQLPENSFESSNHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQLKLVLKKKLDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSI+KLDGKVFLETDLDRESVESLHFT RAADSGYPKQLSTAN+TVIVKDINDN+PFLPKSIYLYV ENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDRE+TTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKENKMKDNVEYSNEESDNFDFRINNNVVIIIVLICAAALFIIMMSLAT+LLVCRKFKQDRNYSQRERFQLKQNFRIWKSNVKKSFINKRQQELNQVEPVSGQSLIQKNMNNEDRLQ+NSVNKSNHSYFLNPLTLEYNPNSSTIENKDLPINLQKYSTRQFGEFQNEILIPGVSTYFDYNHSSGETDNKKQNLEVMTSKSPLSLSFIDSSSSKNCAFPAQFQTFTPHFLSGCNV
Sbjct: 1 MNYEEHENFALKFQRMQIIKIFVGFCFAFQLPENSFESSNHKHFTIDIYEELPRKTKVIDLGAQATKWFPTDVNKLQDFGKPIYKFQFFNCEKSSVYFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQLKLVLKKKLDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSISKLDGKVFLETDLDRESVESLHFTIRAADSGYPKQLSTANVTVIVKDINDNYPFLPKSIYLYVFENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDRELTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGDSILSKENKMKDNVEYSNEESDNFDFRINNNVVIIIVLICAAALFIIMMSLATSLLVCRKFKQDRNYSQRERFQLKQNFRIWKSNVKKSFINKRQQELNQVEPVSGQSLIQKNMNNEDRLQVNSVNKSNHSYFLNPLTLEYNPNSSTIENKDLPINLQKYSTRQFGEFQNEILIPGVSTYFDYNHSSGETDNKKQNLEVMTSKSPLSLSFIDSSSSKNCAFPAQFQTFTPHFLSGCNV 1077
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000076665.1 (SMESG000076665.1) HSP 1 Score: 308.531 bits (789), Expect = 2.122e-87 Identity = 235/759 (30.96%), Postives = 371/759 (48.88%), Query Frame = 3
Query: 420 GVITIERRIDRDNLCHLVPTCC----------------PKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAP---GKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSINKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLP-----KSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNN---QTND-LFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIE 2612
G I +++ IDR++LC + CC P N++ + + K + I + I++ DINDNSP +SQ + SE +IG L +A+D D I Y + E E L +I + S Q+ L L + +DRE + Y + A D G PS +G +K+ + + D NDN P+FE + YI++V E+ S ++ LKA D DS NG + Y SS E K F I+S++G++ + LDYE + V A D G S TV +++ D NDN P+IY E T++ K T E P K ++ V D DS G V C L+ +++F L N +KI+ ++S D E+++ IVC D G P+ T+S + + DIND +P F SY V E+ + G + + ATD+D +N ++YSI FSI+ + G + + DRE S + A D G P Q +AN+ + + D NDN P+ S + EN ++ + ++ D DEG+N + T +S P++K F++ PD +I LDRE +E + D+G + + ++V+D ND +P+F+ P+ +++VK+ +GT +A+I AID+DEG NS L+Y S N QT D +F M+ ++G I LQ+ + + Y+L ++V D G P + A I I+
Sbjct: 101 GDIRVKKPIDRESLCGDIGKCCDSEPFCFFELKVLVRVPSINSKISYSSSEKISSTMT-IETIRIKIIDINDNSPHFSQPVKTIEISESIQIGAKIPLPLAVDEDSKNFNIISYRL--ENHEHALFTLIPEWSNFDSTINQIFLKLLQPIDRENVSMYNLNLIATDKGKPSLSGKLKIEIKILDANDNQPIFENSTYIVNVKESEISGHLILLLKATDKDSGENGLVMYYFSSDVTSEVRKKFHIDSSTGWLSISETLDYEKVKYYTFNVIARDSGTDAAFSKATVKVSVVDCNDNPPKIYLE--YVTDSGKRTLIEGPTTINKEYSIVIVSDPDSGNGGLVQCDLK--GSQKFILVPPNNREGSTWKINLVESLDYEERNVERFIIVCHDRGEPQLTSSHEEEIIIRDINDNSPIFEHPSYHQTVEENNQAGIVVLKVVATDRDSDLNGKINYSIDSLSVSYFSIDPVTGTIRSKISFDREKRASYQLSVFARDLGEPAQSGSANVLITITDQNDNTPYFQGLNGGGSYIFEIKENGPSNAIIGTIHAEDPDEGINGQVLYTFLS-------------PVEK-------------FTIHPDQGIIRTNQQLDRENKAVHEFSVRVIDKGILRQENSVSVTVSVIDENDNEPRFVIPTNDSTSVKISYLDTAGTLVARIEAIDKDEGPNSHLDYQIISGNSRDQTQDKIFFMDQKNGDIFLQRALTR-QDMGVYILKMMVSDQGNPPRKSYANYVIKID 825
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000059376.1 (SMESG000059376.1) HSP 1 Score: 283.878 bits (725), Expect = 9.484e-80 Identity = 234/758 (30.87%), Postives = 371/758 (48.94%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTI-----KSDDDFSHIIV--LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKD---AKIFSINKLDGKVFLETDLDRES----VESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATD-RGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTV-KVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESI 2618
Y ++ NG + +R+IDRD+LC + CC K + C++ +++ + S I+ +I ++D ND+ P + SE + + L +A+D D + Y I++ +LS I + T K + L LK +LDRE D+Y + A DGG+P+ G + V + V D NDN PVFE Y + V E+ + + Q++A D D N +I Y++ S +F ++ SG +++ LDYE LI+ A + +T T+ +N+ ++ND P I+ + +A I+E E V + +V+DKD GKV C L+ +E F L R N P YKI T + DRE SK + IVC D+G P + + V + D ND P + S IFHV+E+ PGT + I+ATDKD+G+N L+YSI + +I+ G + +DRE+ + L + +DSG PKQ S +I +++ D NDN P +S + + V EN L Q+ V+D DE + ++ + RK + I S N + L+ ES LDRE YE+VI ATD G + + + VLD+ND P FIFP N T+ KV R G + A D+D + F N+ +N+LF ++P +G+I + + + S + + +I+ V+D+G P L +++I I+ I
Sbjct: 61 YLHLDSNNGKLFAKRKIDRDSLCSEIELCC-KSDIICSVSVSVAMTAAQPSSKLSDPIIGKFLIVIEDRNDHKPNFEYPIFNLSISESCPVSTTFQLPLAIDKDSDKYSVKSYKF---ISKSDLS-IFSLETQFIDRKMSVYLRLKNRLDREDTDQYSLTIAAVDGGDPALTGVLVVHILVLDVNDNPPVFENTRYNVRVKESQMISDSIAQVRATDRDIGENAEIFYKLDS-------GMFRVDELSGSVYMISPLDYEKDQEYKLIITARNRIPGVNTATATLTVNVININDEKPVIFVDYFNNWQHASISEYETAPAFVCIVTVKDKDIGIAGKVQCQLDN-HHELFDL-RQNSP--GQYKIHTRQQLDRETNSKYSLSIVCKDQGTPSLSADTIIPVVILDKNDNKPEINSPS-IFHVSENKPPGTIVTKIDATDKDDGLNGKLTYSITDAQNLVSSYLTIDSQTGIIRTLQKIDREATNPPLTKLDLSVTVSDSGTPKQSSIKSIQILIDDENDNAPQFGQSTFRFSVTENEAPIYRLGQIEVSDPDETGSVRLGISFIKSN-----NRKSPFSI--------TSEKNRFW-------LMTTES-LDREELDFYELVIIATDGAGYKSHTASATVNVTVLDINDNPPIFIFPRSGNETIPKVPYRQQPGYLVLTASANDKDNLPRGNGKLYFSINSNSNNLFNIDPHNGEIRIHRQMGIS-DIGDHFIIIKVEDDGTPVLSSERQIQIKIQDI 779
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000059376.1 (SMESG000059376.1) HSP 1 Score: 283.878 bits (725), Expect = 1.019e-79 Identity = 234/758 (30.87%), Postives = 371/758 (48.94%), Query Frame = 3
Query: 396 YFEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTI-----KSDDDFSHIIV--LVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSISPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAVYIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYTTISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEPSRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHLEPIANEEFSLERMNIPLTVMYKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKD---AKIFSINKLDGKVFLETDLDRES----VESLHFTTRAADSGYPKQLSTANITVIVKDINDNFPFLPKSIYLY-VLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESGLDREVTTKYEIVIEATD-RGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTV-KVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESI 2618
Y ++ NG + +R+IDRD+LC + CC K + C++ +++ + S I+ +I ++D ND+ P + SE + + L +A+D D + Y I++ +LS I + T K + L LK +LDRE D+Y + A DGG+P+ G + V + V D NDN PVFE Y + V E+ + + Q++A D D N +I Y++ S +F ++ SG +++ LDYE LI+ A + +T T+ +N+ ++ND P I+ + +A I+E E V + +V+DKD GKV C L+ +E F L R N P YKI T + DRE SK + IVC D+G P + + V + D ND P + S IFHV+E+ PGT + I+ATDKD+G+N L+YSI + +I+ G + +DRE+ + L + +DSG PKQ S +I +++ D NDN P +S + + V EN L Q+ V+D DE + ++ + RK + I S N + L+ ES LDRE YE+VI ATD G + + + VLD+ND P FIFP N T+ KV R G + A D+D + F N+ +N+LF ++P +G+I + + + S + + +I+ V+D+G P L +++I I+ I
Sbjct: 66 YLHLDSNNGKLFAKRKIDRDSLCSEIELCC-KSDIICSVSVSVAMTAAQPSSKLSDPIIGKFLIVIEDRNDHKPNFEYPIFNLSISESCPVSTTFQLPLAIDKDSDKYSVKSYKF---ISKSDLS-IFSLETQFIDRKMSVYLRLKNRLDREDTDQYSLTIAAVDGGDPALTGVLVVHILVLDVNDNPPVFENTRYNVRVKESQMISDSIAQVRATDRDIGENAEIFYKLDS-------GMFRVDELSGSVYMISPLDYEKDQEYKLIITARNRIPGVNTATATLTVNVININDEKPVIFVDYFNNWQHASISEYETAPAFVCIVTVKDKDIGIAGKVQCQLDN-HHELFDL-RQNSP--GQYKIHTRQQLDRETNSKYSLSIVCKDQGTPSLSADTIIPVVILDKNDNKPEINSPS-IFHVSENKPPGTIVTKIDATDKDDGLNGKLTYSITDAQNLVSSYLTIDSQTGIIRTLQKIDREATNPPLTKLDLSVTVSDSGTPKQSSIKSIQILIDDENDNAPQFGQSTFRFSVTENEAPIYRLGQIEVSDPDETGSVRLGISFIKSN-----NRKSPFSI--------TSEKNRFW-------LMTTES-LDREELDFYELVIIATDGAGYKSHTASATVNVTVLDINDNPPIFIFPRSGNETIPKVPYRQQPGYLVLTASANDKDNLPRGNGKLYFSINSNSNNLFNIDPHNGEIRIHRQMGIS-DIGDHFIIIKVEDDGTPVLSSERQIQIKIQDI 784
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000033799.1 (SMESG000033799.1) HSP 1 Score: 274.633 bits (701), Expect = 1.977e-76 Identity = 236/758 (31.13%), Postives = 369/758 (48.68%), Query Frame = 3
Query: 399 FEINPLNGVITIERRIDRDNLCHLVPTCCPKKNNQCNLDLTIKSDDDFSHIIVLVIEVKDINDNSPFWSQNELVTQFSEGSEIGDSKSLTVALDNDFGTNGISYYSI-SPEITEFELSYIINTNTMMYSNKEQXXXXXXXXXDREKIDKYEFIVNAFDGGNPSFNGSIKVIVAVTDENDNSPVFEKAV-YIISVNENLQSNTPVIQLKAIDADSEMNGKIEYQISSLTKPEYAKLFSIESNSGYIHVRWELDYETYT---TISLIVEANDMGNLRRGSTCTVIINIRDLNDNSPEIYFEP-SRFTNNAKITENEAPGKLVAVFSVQDKDSNENGKVTCHL-EPIANEEFSLERM---NIPLTVM-YKISTLKSFDREQKSKVTAHIVCFDEGNPRQTTSGSVSVGVEDINDEAPHFSEKSYIFHVNEDVKPGTYLFTINATDKDEGINALLSYSIFGKDAKIFSI-NKLDGKVFLETDLDRESVESLHFTTRAADSGYPKQLSTANITVIVKDINDNFP-FLPKSIYLYVLENHTADVPLVQVNVTDADEGLNSETKVTLVSETATTLIKRKDEYPIQKLFRDVTKSFSNSLFSLLPDGKLIIRESG--LDREVTTKYEIVIEATDRGNPPKSTKGIIYINVLDVNDCKPKFIFPSGSNSTVKVKPRTVSGTTIAQIIAIDEDEGKNSELEYSFKSNNQTNDLFLMNPESGKISLQQTIQESHKVCCYVLIVVVKDNGIPRLEDTARLRIIIESINGD 2627
F+INP N ++ I IDR++L N + + DF I L I+++DINDNSP + + + E + G + L VA D+D+G N YSI + F+L + N + + K DRE+ D+YE + A D G P G IK+ + + D ND++P F+ Y+I V E+ + + +K D D E I I+S + PE + F + + SG + LDYE+ TI +I N + NL +T TV N+ D+NDN P+I + S ++N K+ EN+ VA+ +V D DS NG V C+L EP + F L N P + Y+I TL+ FDRE S + C D+G P ++ ++++ +ED ND P FS+ + + E++ PG+ +FT+ ATD D G NA + Y I K I SI N G V DRE S+ F A D P S+ +T+ ++D ND P FL + + + E ++ V +V D D NS+ + T N L+ L DG I E G LDREV + Y++ +EA D G P +S+ I+ I + D+ND PKF P S K+ V GT I +++A D+DE +N ++ Y +N F+++ +SG++ + +T+ + ++ L+++ KDNG P TA L+++ ++ + D
Sbjct: 86 FKINPHNQIVVI-NSIDRESL------------NPVDCIVNKTKPKDF-QIFQLPIDIEDINDNSPIFDKLSYNIEIDENIQSGHIQQLPVARDSDYGINSEIIYSIEGKDKGFFKLLQMKNNKPIFKTMK---------LFDREERDRYELVFIATDKGIPKKTGEIKIYIKIRDLNDHAPEFDMPKDYVIGVKEDAIEGSKICDIKVTDKDDET--LITVLINSNSDPEVKRHFQVSAISGLTLIS-RLDYESSMRKFTIPIIAVDNGIPNLTTSTTITV--NVLDINDNFPQIVIDTLSDSSSNFKLMENKPKESFVAMVTVTDADSEMNGIVDCNLIEPNNKQNFELISRYFNNFPNSKRNYRIVTLREFDRETISHYRVTVQCKDQGLPPLSSQQTITIWIEDENDNPPSFSKFFFQDRIKENIMPGSPIFTLIATDPDIGKNAKIIYQIPEKYQNIISIPNPSTGIVTNLVSFDREMNTSITFKAFALDEFNPLLNSSVEVTLEIEDENDCIPMFLSSAYHFKIKEGYSGWVG--KVEAYDNDSNSNSD------------------------IIFSFTGFLHNHLWILKSDGN-IFSEKGIQLDREVQSTYQLTVEAKDNGVPSRSSSVIVQIQLEDINDNSPKFSQPLDSGYMKKITETLVPGTLITKVMATDDDENENGKVTYLLANNK----YFIIDEKSGEVFINRTL-DRLELVPRRLLIMAKDNGTPSFTTTATLQLLFQNEDED 783 The following BLAST results are available for this feature:
BLAST of Protocadherin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30016728 ID=SMED30016728|Name=Protocadherin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3487bpback to top protein sequence of SMED30016728-orf-1 >SMED30016728-orf-1 ID=SMED30016728-orf-1|Name=SMED30016728-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1078bp MNYEEHENFALKFQRMQIIKIFVGFCFAFQLPENSFESSNHKHFTIDIYEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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