Protein unc-45 homolog A

Overview


Name	Protein unc-45 homolog A
Smed ID	SMED30016727
Length (bp)	3073

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein unc-45 homolog A (SMED30016727) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein unc-45 homolog A (SMED30016727) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein unc-45 homolog A (SMED30016727) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein unc-45 homolog A (SMED30016727) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016727

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
neoblast	SMED30016727	SMESG000054342.1	dd_Smed_v4_6344_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30016727	SMESG000054342.1	dd_Smed_v4_6344_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

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Homology

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BLAST of Protein unc-45 homolog A vs. Ensembl Human
Match: UNC45A (unc-45 myosin chaperone A [Source:HGNC Symbol;Acc:HGNC:30594])

HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0
Identity = 342/959 (35.66%), Postives = 537/959 (56.00%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD+  AL  Y   L   D T  ++   ++N++ C+LK+  +D   +   KA++    D K+LYRRS A   L +  +A  D ++ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +  I+      +L +   M    +++ AA R L  +      +T+    + G +   +++          A   L+ +   L +   K +R K            G++   P          A+ +   +  LL       +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG +    +  P +      +  T  ++M+ +ILL+ ++DDL  D +RE F  LC +++      + +  K+ A   +  L QGP +AG+  L  SG+++ ++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK +  D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V D  AL+ L  +++      L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   ++ +EL+SR++L++V   + RG ++  GGG+ALI LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRA+ ECMCNL +  EV++ F  + NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++  ++  +QHR   ++ NM V  SRE    ++ S M EI+  L+K  D +   V   A   L+  V + LI+P
Sbjct:    8 QLRKEGNELFKCGDYGGALAAYTQALGL-DATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMG-ETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQAVSLAACHLLQVMFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSL---QDPPGE------LAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKCSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRLEERSVLFAVASALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMVCMVK--TESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDEL-LQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSNQELQHRGAVVVLNM-VEASREIASTLMESEMMEILSVLAK-GDHS--PVTRAAAACLDKAVEYGLIQP 924

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Human
Match: UNC45A (unc-45 myosin chaperone A [Source:HGNC Symbol;Acc:HGNC:30594])

HSP 1 Score: 552.747 bits (1423), Expect = 0.000e+0
Identity = 342/959 (35.66%), Postives = 537/959 (56.00%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD+  AL  Y   L   D T  ++   ++N++ C+LK+  +D   +   KA++    D K+LYRRS A   L +  +A  D ++ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +  I+      +L +   M    +++ AA R L  +      +T+    + G +   +++          A   L+ +   L +   K +R K            G++   P          A+ +   +  LL       +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG +    +  P +      +  T  ++M+ +ILL+ ++DDL  D +RE F  LC +++      + +  K+ A   +  L QGP +AG+  L  SG+++ ++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK +  D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V D  AL+ L  +++      L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   ++ +EL+SR++L++V   + RG ++  GGG+ALI LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRA+ ECMCNL +  EV++ F  + NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++  ++  +QHR   ++ NM V  SRE    ++ S M EI+  L+K  D +   V   A   L+  V + LI+P
Sbjct:   23 QLRKEGNELFKCGDYGGALAAYTQALGL-DATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMG-ETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQAVSLAACHLLQVMFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSL---QDPPGE------LAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKCSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRLEERSVLFAVASALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMVCMVK--TESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDEL-LQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSNQELQHRGAVVVLNM-VEASREIASTLMESEMMEILSVLAK-GDHS--PVTRAAAACLDKAVEYGLIQP 939

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Human
Match: UNC45A (unc-45 myosin chaperone A [Source:HGNC Symbol;Acc:HGNC:30594])

HSP 1 Score: 551.206 bits (1419), Expect = 9.020e-179
Identity = 342/959 (35.66%), Postives = 537/959 (56.00%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD+  AL  Y   L   D T  ++   ++N++ C+LK+  +D   +   KA++    D K+LYRRS A   L +  +A  D ++ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +  I+      +L +   M    +++ AA R L  +      +T+    + G +   +++          A   L+ +   L +   K +R K            G++   P          A+ +   +  LL       +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG +    +  P +      +  T  ++M+ +ILL+ ++DDL  D +RE F  LC +++      + +  K+ A   +  L QGP +AG+  L  SG+++ ++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK +  D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V D  AL+ L  +++      L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   ++ +EL+SR++L++V   + RG ++  GGG+ALI LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRA+ ECMCNL +  EV++ F  + NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++  ++  +QHR   ++ NM V  SRE    ++ S M EI+  L+K  D +   V   A   L+  V + LI+P
Sbjct:  163 QLRKEGNELFKCGDYGGALAAYTQALGL-DATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDMG-ETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQAVSLAACHLLQVMFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSL---QDPPGE------LAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKCSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRLEERSVLFAVASALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMVCMVK--TESPVLTSSCRELLSRVFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDEL-LQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSNQELQHRGAVVVLNM-VEASREIASTLMESEMMEILSVLAK-GDHS--PVTRAAAACLDKAVEYGLIQP 1079

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Human
Match: UNC45B (unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304])

HSP 1 Score: 508.449 bits (1308), Expect = 3.808e-164
Identity = 339/963 (35.20%), Postives = 531/963 (55.14%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL--NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQT---LLQACNSKKLSATGRDSILEILVRFVPSKEGI--NWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL-TDETMKNVVTCAEESLEALVNHKLIKPI 2953
              KE GN +F+  D+  A   Y   L    +T D+ L    Y+N++ C LK   +    S   +A+ I+  D K+LYRR  A  +L K  +A  D ++   L+P+N+ +QE +R +   I+ ++    S   +V  MF +L   +   D + K+ NNL VL RE + +  I+ +    +LL+      P  ++ AA R LS +    C          G Q  A +I  +V          ++ I S ++   +          +    S S   +   R + +  V     D  Q    LL    SKK+S  GRD  L +L + VP K+    + ++T+   + G  K+L+V          P   + + L D T   +M  +IL+  +YDDL  D +R+ FR +C +++      + M+  + A   +  + QGPF+ G+ +LG  G+++ ++ L  SE  + Q +A++A++ A TK  +   II + + + ++IYKT  ++ +KIR LVG+CKLGS GG D  +   AEGS  +LAK CRK+L    N + D    RWA EGLAYL+LDADVK+  V D  AL+ +  + K +    LY +   L N TNSYD  E++PE+++LAK++KQH+PE H KD   FI  R++ L+K  +   L  + + ADS+  + + +KEL++R++L++    + RG I+  GGGKALI LAL+ TD GKV AA ALAK+A   NP IAFPG+R  EV+RPL++LL  +  GLQN+E+L+ LTNL+   D  R++I KE+ L  +E YMFE H+ LR+A+ ECMCN++L  EV+ERFL + NDR+KL+VLLC E +D  +  AA+G LA+L+ +  +   K+++V   W EI+Q +      ++QHR + +  N++   + E  + +V S + EI+  + K   DE    VV  A E L   +++  IKP+
Sbjct:    8 QLKEEGNRHFQLQDYKAATNSYSQALK---LTKDKALLATLYRNRAACGLKTESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSIQEKLRVQFSTDSRVQKMFEILLDENSEADKREKAANNLIVLGREEAGAEKIFQNNGVALLLQLLDTKKP-ELVLAAVRTLSGM----CS---------GHQARATVILHAV---------RIDRICSLMAVENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLAIHDNSRTIYVVDNGLRKILKVVG------QVPDLPSCLPLTDNT---RMLASILINKLYDDLRCDPERDHFRKICEEYITGKFDPQDMDKNLNAIQTVSGILQGPFDLGNQLLGLKGVMEMMVALCGSERETDQLVAVEALIHASTKLSRATFIITNGVSLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGTDYGLRQFAEGSTEKLAKQCRKWL---CNMSIDTRTRRWAVEGLAYLTLDADVKDDFVQDVPALQAMFELAKTSDKTILYSVATTLVNCTNSYDVKEVIPELVQLAKFSKQHVPEEHPKDKKDFIDMRVKRLLKAGVISALACMVK-ADSAILT-DQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHALAKIAAVSNPDIAFPGERVYEVVRPLVRLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKERALPDIENYMFENHDQLRQAATECMCNMVLHKEVQERFLADGNDRLKLVVLLCGEDDD-KVQNAAAGALAMLTAAHKKLCLKMTQVTTQWLEILQRLCLHDQLSVQHRGLVIAYNLLAADA-ELAKKLVESELLEILTVVGKQEPDEKKAEVVQTARECLIKCMDYGFIKPV 928

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Human
Match: UNC45B (unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304])

HSP 1 Score: 505.368 bits (1300), Expect = 5.951e-163
Identity = 340/965 (35.23%), Postives = 532/965 (55.13%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL--NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQT---LLQACNSKKLSATGRDSILEILVRFVPSKEGI--NWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIE--CLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL-TDETMKNVVTCAEESLEALVNHKLIKPI 2953
              KE GN +F+  D+  A   Y   L    +T D+ L    Y+N++ C LK   +    S   +A+ I+  D K+LYRR  A  +L K  +A  D ++   L+P+N+ +QE +R +   I+ ++    S   +V  MF +L   +   D + K+ NNL VL RE + +  I+ +    +LL+      P  ++ AA R LS +    C          G Q  A +I  +V          ++ I S ++   +          +    S S   +   R + +  V     D  Q    LL    SKK+S  GRD  L +L + VP K+    + ++T+   + G  K+L+V          P   + + L D T   +M  +IL+  +YDDL  D +R+ FR +C +++      + M+  + A   +  + QGPF+ G+ +LG  G+++ ++ L  SE  + Q +A++A++ A TK  +   II + + + ++IYKT  ++ +KIR LVG+CKLGS GG D  +   AEGS  +LAK CRK+L    N + D    RWA EGLAYL+LDADVK+  V D  AL+ +  + K  T +   LY +   L N TNSYD  E++PE+++LAK++KQH+PE H KD   FI  R++ L+K  +   L  + + ADS+  + + +KEL++R++L++    + RG I+  GGGKALI LAL+ TD GKV AA ALAK+A   NP IAFPG+R  EV+RPL++LL  +  GLQN+E+L+ LTNL+   D  R++I KE+ L  +E YMFE H+ LR+A+ ECMCN++L  EV+ERFL + NDR+KL+VLLC E +D  +  AA+G LA+L+ +  +   K+++V   W EI+Q +      ++QHR + +  N++   + E  + +V S + EI+  + K   DE    VV  A E L   +++  IKP+
Sbjct:    8 QLKEEGNRHFQLQDYKAATNSYSQALK---LTKDKALLATLYRNRAACGLKTESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSIQEKLRVQFSTDSRVQKMFEILLDENSEADKREKAANNLIVLGREEAGAEKIFQNNGVALLLQLLDTKKP-ELVLAAVRTLSGM----CS---------GHQARATVILHAV---------RIDRICSLMAVENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLAIHDNSRTIYVVDNGLRKILKVVG------QVPDLPSCLPLTDNT---RMLASILINKLYDDLRCDPERDHFRKICEEYITGKFDPQDMDKNLNAIQTVSGILQGPFDLGNQLLGLKGVMEMMVALCGSERETDQLVAVEALIHASTKLSRATFIITNGVSLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGTDYGLRQFAEGSTEKLAKQCRKWL---CNMSIDTRTRRWAVEGLAYLTLDADVKDDFVQDVPALQAMFELAKAGTSDKTILYSVATTLVNCTNSYDVKEVIPELVQLAKFSKQHVPEEHPKDKKDFIDMRVKRLLKAGVISALACMVK-ADSAILT-DQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHALAKIAAVSNPDIAFPGERVYEVVRPLVRLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKERALPDIENYMFENHDQLRQAATECMCNMVLHKEVQERFLADGNDRLKLVVLLCGEDDD-KVQNAAAGALAMLTAAHKKLCLKMTQVTTQWLEILQRLCLHDQLSVQHRGLVIAYNLLAADA-ELAKKLVESELLEILTVVGKQEPDEKKAEVVQTARECLIKCMDYGFIKPV 930

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Celegans
Match: unc-45 (UNC-45 [Source:UniProtKB/TrEMBL;Acc:G5EG62])

HSP 1 Score: 365.155 bits (936), Expect = 2.812e-110
Identity = 292/986 (29.61%), Postives = 498/986 (50.51%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL---NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTD-DMKLKSLNNLTVLIRETSNSL--IWCHQDRNILLKFCQMDLPINIIEAAH----------RCLSLLFLPS--CEKTLEIFKLHGPQYFAN----MIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEG---INWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLT-----DEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMF-EEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSD----IRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL--TDETMKNVVTCAEESLEALVNHKLIK 2947
              ++ GN   K  D+ KA E+Y   L     TD++K      Y+N++M  LK   F+   S C KAL+    D K+L+RRSLA   L     A  DAK+ + L P +K   E ++ + K    +++   S   KV  M  L  + +  D + K+ +LNNL VL RE+ +    +W   ++  L+ F      +N+I  A           R L      S  C K L +    GP+        M   S  +     G  ++ + + ++++   +                   +P    ++ EA   ++   L  L +     K+ A  R++ +++ ++ +   +G     W+   +  E G   LL+V           SQ   +     + +T+  VAI L  + +D++ D  R  F++    F   L++     DE  + +++ +  +  + QGP + G  ++    +   +L +  S+    Q IA + IV   +K ++ ++++K  IP+   +Y +    +K+RALVG+CK+G+ GG D S  ++ E + + LAK+C+KFL +    + D  + R+A EGL+YLSLDADVKE +V+D   L+ L+ + K     C+Y L  + AN++N+++KP++  EM++LA++AK H+PETH KD++ +++ R+  L+++       ++     S   S+NA  ELI+R  L+   YE  RG II  GG    + L  + +  GK+ A  A+AK+    +P I+FPGQR+ EV++PL  LL  +  G  N++SL+ LTNLASV D  R RI+KEK + ++E + F  +HE LR A+ E + NLL  ++  E  +    DR+KL VL   EVE+  L +A++ G AIL+ D     R +D   ++ +W E+ + +    D   Q R +  + N I++ S + C  IV+S +F +++A++KL   ++        A+  LEA     LIK
Sbjct:   10 EIRDEGNAAVKDQDYIKADELYTEALQL--TTDEDKALRPVLYRNRAMARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLSPNDKGIVEVLQRLVKANNDKIKQTTSLANKVTDMEKLAFRGEAKDTEQKMTALNNLLVLCRESESGATGVW---NQGALVPFV-----LNLINDASENEEVTVTAIRILDETIKNSVRCMKFLAMHDPDGPKSVRFVCRLMCKKSTKDFVDATGILVQRVFNAMAKMDRQK-----------------EMKPDP--EVAEANKIWIIRVLLELQEMLQDPKVGAVQRETCIDLFLKNLMHMDGGIPRGWSWKFV-EERGLLALLDVA----------SQIPELCEYPVSAETRQHVAICLQRLEEDMVFDTKRTIFKEKVDMFFNALISRCTNDDEGHKYRIKLSCFLITMLQGPVDIGINLITNDQLTPIMLEMAASQDHLMQGIAAELIVATVSKHERAINMLKVGIPVLRALYDSEDPTVKVRALVGLCKIGAAGGDDISKATMKEEAVISLAKTCKKFLLETEKYSVD--IRRYACEGLSYLSLDADVKEWIVDDSLLLKALVLLAKKAGALCVYTLATIYANLSNAFEKPKVDEEMVKLAQFAKHHVPETHPKDTEEYVEKRVRALVEEGAVPACVAV-----SKTESKNAL-ELIARSLLAFAEYEDLRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGAKADPMISFPGQRAYEVVKPLCDLLHPDVEGKANYDSLLTLTNLASVSDSIRGRILKEKAIPKIEEFWFMTDHEHLRAAAAELLLNLLFFEKFYEETVAPGTDRLKLWVLYSAEVEEERLSRASAAGFAILTEDENACARIMD---EIKSWPEVFKDIAMHEDAETQRRGLMGIAN-IMHSSNKLCSEIVSSEVFRVLVAVTKLGTINQERAGSTEQAKRGLEAAEKFGLIK 943

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BLAST of Protein unc-45 homolog A vs. Ensembl Celegans
Match: sti-1 (Stress-induced-phosphoprotein 1 [Source:UniProtKB/Swiss-Prot;Acc:O16259])

HSP 1 Score: 57.7658 bits (138), Expect = 1.896e-8
Identity = 31/116 (26.72%), Postives = 57/116 (49.14%), Query Frame = 2

Query:   89 EMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIR 436
            E+    K  GNEYFK GD+  A+  Y   +      D E    Y N++ C  K+++F   +  CD  +++     K   R++   + + ++S+AQ   +  + +DP N+  +E +R
Sbjct:  138 ELAQEEKNKGNEYFKKGDYPTAMRHYNEAVKR----DPENAILYSNRAACLTKLMEFQRALDDCDTCIRLDSKFIKGYIRKAACLVAMREWSKAQRAYEDALQVDPSNEEAREGVR 249

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Fly
Match: unc-45 (gene:FBgn0010812 transcript:FBtr0081788)

HSP 1 Score: 531.176 bits (1367), Expect = 6.164e-173
Identity = 325/958 (33.92%), Postives = 541/958 (56.47%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLN-YYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRE-TSNSLIW---CHQDRNILLKFCQ-MDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQY-LENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVA--QYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
            +K+ GNE FK+  +++A+E Y  G   K  +  ++L  +YKN++  YLK+ K++  +  C ++LK +  DPK+L+RR+ A+  L KF EA  DA  L   DP NK  Q  ++ +   +  +   N     KV  M +L        D +  + NNL VL +E T   L++   C      L K  +  D+ +N++      ++ L   S E+T  +    G  +F  ++     E+C    Q+ L+ IL+ LS +K+                     +P  + + +      + ++  L  L+ +   + +S   RD ++E++ R V     + W + L+   G   +LL+V        S      + S +D T  +    ++ LA IY+++  D+ + +F D   +++ D L    MESKV     I  L  GP + G+ V+ + GILQ +L +  ++    QR++ + ++ A +KKDK  ++ +  + I + +Y + +D +++RALVG+CKLGS GG+D++I    +G+ L+LA++CR+FL        D  + RWA++GLAYL+LDA+ KE L+ D+ ++  L+ + +     CLY +     N+ N+Y+K E+LPEM+ELAK+AKQHIPE HE D   FI  RI  L  + ++  L +L +       S N S+ELI+R+  +V   ++ RG ++Q GG KAL+ +AL+ T+ GK  A QALA++ ITINP ++F GQRSL+VIRPL+ LL+ + T L+NFESLMALTNLAS+++  R+RIIKE+G+S++EYY+ E+H  L RA+ +C+CNL++ ++V + F G  NDRVK L LLC E ED     A +G LAI++S  ++  +K+  + +W +I+  ++A   PA+QHR + ++ NMI N   E  + +  +++ E++  L +L D+T       A + L A   +++I+
Sbjct:   16 YKDKGNEAFKASRWEEAVEHY--GKAIKAGSKHKELAVFYKNRAAAYLKLGKYENAVEDCTESLKAAPGDPKALFRRAQAYEALEKFEEAYKDATALFKADPGNKTVQPMLQRLHVVVEERSARNAKTSTKVKQMMDLTFDLATPIDKRRAAANNLVVLAKEQTGAELLYKDHCIAKVASLTKVEKDQDIYVNMV----HLVAALCENSVERTKGVLTELGVPWFMRVL-DQKHENCVSTAQFCLQTILNALSGLKN---------------------KPDSKPEKELCTRNNREIDTLLTCLVYSITDRTISGAARDGVIELITRNV-HYTALEWAERLVEIRG-LCRLLDVC-------SELEDYKYESAMDITGSSSTIASVCLARIYENMYYDEAKARFTDQIDEYIKDKLLAPDMESKVRVTVAITALLNGPLDVGNQVVAREGILQMILAMATTDDELQQRVSCECLIAASSKKDKAKALCEQGVDILKRLYHSKNDGIRVRALVGLCKLGSYGGQDAAIRPFGDGAALKLAEACRRFL---IKPGKDKDIRRWAADGLAYLTLDAECKEKLIEDKASIHALMDLARGGNQSCLYGVVTTFVNLCNAYEKQEMLPEMIELAKFAKQHIPEEHELDDVDFINKRITVLANEGITTALCALAKTE-----SHN-SQELIARVLNAVCGLKELRGKVVQEGGVKALLRMALEGTEKGKRHATQALARIGITINPEVSFSGQRSLDVIRPLLNLLQQDCTALENFESLMALTNLASMNESVRQRIIKEQGVSKIEYYLMEDHLYLTRAAAQCLCNLVMSEDVIKMFEG-NNDRVKFLALLC-EDEDEETATACAGALAIITSVSVKCCEKILAIASWLDILHTLIANPSPAVQHRGIVIILNMI-NAGEEIAKKLFETDIMELLSGLGQLPDDTRAKAREVATQCLAAAERYRIIE 924

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Fly
Match: unc-45 (gene:FBgn0010812 transcript:FBtr0347497)

HSP 1 Score: 531.176 bits (1367), Expect = 6.164e-173
Identity = 325/958 (33.92%), Postives = 541/958 (56.47%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLN-YYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRE-TSNSLIW---CHQDRNILLKFCQ-MDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQY-LENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVA--QYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
            +K+ GNE FK+  +++A+E Y  G   K  +  ++L  +YKN++  YLK+ K++  +  C ++LK +  DPK+L+RR+ A+  L KF EA  DA  L   DP NK  Q  ++ +   +  +   N     KV  M +L        D +  + NNL VL +E T   L++   C      L K  +  D+ +N++      ++ L   S E+T  +    G  +F  ++     E+C    Q+ L+ IL+ LS +K+                     +P  + + +      + ++  L  L+ +   + +S   RD ++E++ R V     + W + L+   G   +LL+V        S      + S +D T  +    ++ LA IY+++  D+ + +F D   +++ D L    MESKV     I  L  GP + G+ V+ + GILQ +L +  ++    QR++ + ++ A +KKDK  ++ +  + I + +Y + +D +++RALVG+CKLGS GG+D++I    +G+ L+LA++CR+FL        D  + RWA++GLAYL+LDA+ KE L+ D+ ++  L+ + +     CLY +     N+ N+Y+K E+LPEM+ELAK+AKQHIPE HE D   FI  RI  L  + ++  L +L +       S N S+ELI+R+  +V   ++ RG ++Q GG KAL+ +AL+ T+ GK  A QALA++ ITINP ++F GQRSL+VIRPL+ LL+ + T L+NFESLMALTNLAS+++  R+RIIKE+G+S++EYY+ E+H  L RA+ +C+CNL++ ++V + F G  NDRVK L LLC E ED     A +G LAI++S  ++  +K+  + +W +I+  ++A   PA+QHR + ++ NMI N   E  + +  +++ E++  L +L D+T       A + L A   +++I+
Sbjct:   16 YKDKGNEAFKASRWEEAVEHY--GKAIKAGSKHKELAVFYKNRAAAYLKLGKYENAVEDCTESLKAAPGDPKALFRRAQAYEALEKFEEAYKDATALFKADPGNKTVQPMLQRLHVVVEERSARNAKTSTKVKQMMDLTFDLATPIDKRRAAANNLVVLAKEQTGAELLYKDHCIAKVASLTKVEKDQDIYVNMV----HLVAALCENSVERTKGVLTELGVPWFMRVL-DQKHENCVSTAQFCLQTILNALSGLKN---------------------KPDSKPEKELCTRNNREIDTLLTCLVYSITDRTISGAARDGVIELITRNV-HYTALEWAERLVEIRG-LCRLLDVC-------SELEDYKYESAMDITGSSSTIASVCLARIYENMYYDEAKARFTDQIDEYIKDKLLAPDMESKVRVTVAITALLNGPLDVGNQVVAREGILQMILAMATTDDELQQRVSCECLIAASSKKDKAKALCEQGVDILKRLYHSKNDGIRVRALVGLCKLGSYGGQDAAIRPFGDGAALKLAEACRRFL---IKPGKDKDIRRWAADGLAYLTLDAECKEKLIEDKASIHALMDLARGGNQSCLYGVVTTFVNLCNAYEKQEMLPEMIELAKFAKQHIPEEHELDDVDFINKRITVLANEGITTALCALAKTE-----SHN-SQELIARVLNAVCGLKELRGKVVQEGGVKALLRMALEGTEKGKRHATQALARIGITINPEVSFSGQRSLDVIRPLLNLLQQDCTALENFESLMALTNLASMNESVRQRIIKEQGVSKIEYYLMEDHLYLTRAAAQCLCNLVMSEDVIKMFEG-NNDRVKFLALLC-EDEDEETATACAGALAIITSVSVKCCEKILAIASWLDILHTLIANPSPAVQHRGIVIILNMI-NAGEEIAKKLFETDIMELLSGLGQLPDDTRAKAREVATQCLAAAERYRIIE 924

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Fly
Match: Stip1 (gene:FBgn0024352 transcript:FBtr0078131)

HSP 1 Score: 62.003 bits (149), Expect = 1.945e-9
Identity = 38/108 (35.19%), Postives = 56/108 (51.85%), Query Frame = 2

Query:   89 EMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKN 412
            E     KE GN +FK GD+  A++ Y   +  K   DD KL  Y N++ CY K+  FDL +  CD  +K+ +   K   R+      + + S+AQA  +K + LDP N
Sbjct:  308 EKAEEEKEQGNLFFKKGDYSTAVKHYTEAI--KRNPDDPKL--YSNRAACYTKLAAFDLGLKDCDTCIKLDEKFIKGYIRKGKILQGMQQQSKAQAAYQKALELDPNN 411

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Fly
Match: spag (gene:FBgn0015544 transcript:FBtr0072256)

HSP 1 Score: 56.225 bits (134), Expect = 1.339e-7
Identity = 32/109 (29.36%), Postives = 58/109 (53.21%), Query Frame = 2

Query:   86 FEMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKN 412
            ++     K+ GN Y K G+++KA+  Y   +    +   + + Y+ N+++CYLK   FD  +  C+ A+ + K+  K+ YRR  A  +L    EA  D   ++ ++PKN
Sbjct:   93 YKKANDIKDRGNTYVKQGEYEKAIVAYSTAIA---VYPHDPI-YHINRALCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQANESLGNNMEALKDCTTVLAIEPKN 197

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Fly
Match: PpD3 (gene:FBgn0005777 transcript:FBtr0082129)

HSP 1 Score: 53.1434 bits (126), Expect = 1.209e-6
Identity = 41/170 (24.12%), Postives = 78/170 (45.88%), Query Frame = 2

Query:   86 FEMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGK----VNAMFNLLKQSDLTDDMKLKSLNNLTVLIR 583
            F     +K  GNE  K+ +F KA++MY   +   ++  +  + YY N+S+ +L+   F   +     A+K      K  YRR+ A ++L KF +A  D + +    P +K  +    E  K ++ +       V K    ++ M++ ++   + DD K   L +  V ++
Sbjct:   46 FAAAEQYKNQGNEMLKTKEFSKAIDMYTKAI---ELHPNSAI-YYANRSLAHLRQESFGFALQDGVSAVKADPAYLKGYYRRAAAHMSLGKFKQALCDFEFVAKCRPNDKDAKLKFTECNKIVKMRAFERAIAVDKPEKTLSEMYSDMENITIEDDYKGPQLEDGKVTLK 211

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Zebrafish
Match: unc45b (unc-45 myosin chaperone B [Source:NCBI gene;Acc:266640])

HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0
Identity = 341/961 (35.48%), Postives = 542/961 (56.40%), Query Frame = 2

Query:   95 TTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNY-YKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVP--SKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMK-NVVTCAEESLEALVNHKLIKPI 2953
            +   KE GN++F++G+ D+A++ Y   + T    D + L   Y+N+S C+LK   +    S   KA+ +   D K+LYRR  AF  L K   A  D ++   ++PKNK + E +R +  +I+ +++   S   +V  MF++L   +   + + K+ NNL VL RE + +  I+ +    +L++      P  +I AA R LS +      +   I    G     +++     E         + +   LS   D R                 N+   +   +D +  + + D L  LL+   SK +S  GRD  L +L + VP  +K+  + +K L   + G  K+L+V          P   + + +   T  T++  ++LL+ +YDDL  D +R++FRD+C D++        M+  + A N +  + QGPF+ G+ + G+ G+++ ++ L  SE    Q +A++A++ A TK  K    I + + + +E+YK T ++ +KIRALVG+CKLGS GG D S+   AEGS  +LAK CRK+L    N   D    +WA EGLAYL+ DADVK+    DE A+R +  +TK+     LY +   L N TNSYDK EI+PEM++LAK++KQH+PE H KD   FI  R++ L+K  ++  L  + +  +S    Q  +KE+++R++L++    + RG I+  GGGKALI LAL+ TD GK+ A+ ALAK+A   NP IAFPG+R  EV+RPL+ LL  +  G++NFE+L  LTNLA ++D  R +I+KEK L ++E YMFE+HE +R+A+ ECMCNL+   EV++R+L + ND++KLLVLLC E E+  L +AA+G LA+L+ +  +   K++KV   W EI+Q +    +P IQHR +  + NM+ +   +  + +V S+M EI+  ++KL D   K N +  A   L   +++ LIKP 
Sbjct:    9 SVQLKEEGNKHFQAGEIDQAIDCYTKAIKTCKKEDKKALAVIYRNRSACFLKKENYSNAASDATKAIDVDAADIKALYRRCQAFEKLGKLDMAFKDVQRCATIEPKNKTFLETLRRLGAEIQQKLKTTFSTDSRVQNMFDILFSDEPDKEKREKAANNLIVLAREDAGAERIFQNNGVPLLMQLIDTGKP-EMILAAIRTLSGMCTGHRARATAIIHSVGISKLCSIMAVDNEEIALATANLFQCVNDSLSG-GDKR-----------------NYGKEEALVLDSS--KDLKDILLALLEMIASKNVSGHGRDQALNLLTKNVPRQNKKSTDNSKCLFTIDHGLKKILKVCG------QVPDLPDQLPM---TENTQLIASVLLSKLYDDLRCDPERDQFRDICDDYIKSKFDPNDMDKNIHAINTLSGILQGPFDLGNVLAGRQGVMEMMVALCGSEREVDQLVAVEALIHASTKTSKASFFISNGVSLLKEMYKKTKNEKIKIRALVGLCKLGSAGGDDYSMRQFAEGSTEKLAKQCRKWL---CNPTLDVRTRKWAIEGLAYLTNDADVKDDFAEDEPAMRAMFELTKSNDKTILYAVACTLVNCTNSYDKKEIIPEMVQLAKFSKQHVPEQHPKDKKDFIVRRVKRLLKAGVTSALAVMVKADNSILTDQ--TKEMLARVFLALTEDVKDRGIIVAQGGGKALIPLALEGTDKGKIKASHALAKIAAVSNPEIAFPGERIYEVVRPLVSLLGTDRDGMENFEALRGLTNLAGLNDKLRVKILKEKALPEIENYMFEDHEQIRQAATECMCNLVCCKEVQDRYLEDGNDKLKLLVLLCGEDEE-KLQRAAAGALAMLTAAQKKLAVKMTKVTEQWLEILQRLCIHDNPEIQHRGLVTVFNML-DADDQLAKKLVESDMLEILTYVAKLEDNPKKQNAIDAARACLSKAMDNGLIKPF 932

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BLAST of Protein unc-45 homolog A vs. Ensembl Zebrafish
Match: unc45a (unc-45 myosin chaperone A [Source:ZFIN;Acc:ZDB-GENE-050417-158])

HSP 1 Score: 543.888 bits (1400), Expect = 7.333e-178
Identity = 343/963 (35.62%), Postives = 530/963 (55.04%), Query Frame = 2

Query:   95 TTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAV----AQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDI-----RFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
            ++  +E GN +FK+GD  +AL  Y   L   D   +  +  Y+N+S CYLK+  +        K+L +   D K+ +RR+ A   L +  +A  D +K   L+PKNK +Q+ +R++  QI+ +    +S   +V  MF LL  S      + K+  NL VL RE + +      D   LL+         +I +A R L  L      +T+ I    G +    ++ SS       A   L+ +   L++    R + +                       DEA+    ++ +   L+ LL    +  +S  GRDS + +LV+ VP K   N   + +L   + G  K+LEV       E+ P  T +         T M+ ++LL  +YDDL SDK+RE F  LC ++V        ME ++ A   + +L QGP + G+  L  SG++  ++ L  SE    Q++A++A++ A  K  +   I  + + + +E+YK + +D +++RALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N +   +  RWA EGLAYL+LDADVKE LV D++AL+ +  + K+     L+ + + L N TNSYD  +  P+M+ELAKYAKQH+PE H KD   F++ R+ +L++  +   L  + +    SP    A +E I+R+ L++V  ++ RG ++  GGGKAL+ L  ++TD GK+ AAQALAK+ IT NP IAFPG+R  EV+RPL+ LL ++ + LQNFE+LMALTNLA + +  R++IIKEK + ++E YMFEEH+M+R AS ECMCNL L  EV++ +L  E+DR+KLLVL   E +D  L KAASG LA+L+ ++     R  D  S   +W EI+QA++      ++HR V ++ N I+   +   E ++ S   EI+  L+K  D    +V   A+  L+  + + LI+
Sbjct:    5 SSALREEGNNHFKAGDVQQALTCYTKALKISDCPSESAV-LYRNRSACYLKLEDYTKAEEDATKSLDVDPGDIKARFRRAQALQKLGRLDQAFMDVQKCAQLEPKNKAFQDLLRQLGAQIQQKATQLSSTDSRVQQMFKLLLDSSAPIADRQKAAQNLVVLSREDAGAEQIFRNDGVKLLQNLLESKQEELILSALRTLVGLCTGHQSRTMAIVNELGMERLCGVMGSSASSVSLSACHLLQVMFEALTEGMKKRIRGK-----------------------DEAILPEPSRELRSMLRHLLDMLPASSVSGAGRDSAINLLVKQVPRKSVKNPDNSLSLWVIDQGLKKILEVAGTVAEVENGPPLTEN---------THMSCSVLLNKLYDDLKSDKERENFSKLCEEYVQHHFMSSSMERRLRAIQTVSVLLQGPSDVGNVTLELSGLMDSVISLCASEDIVQQQVAVEALIHAAGKAKRASFITANGVALLKELYKKSQNDRIRVRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNESLPPASRRWAIEGLAYLTLDADVKEDLVEDKKALQAMFELAKSEDKTVLFAVGSTLVNCTNSYDVEKPDPQMVELAKYAKQHVPEEHPKDGQPFVEQRVVKLLEAGVVSALVCMVK--QESPAMTEACRECIARVILALVERQEDRGLVVAQGGGKALLPLVSESTDRGKIKAAQALAKITITSNPEIAFPGERVYEVVRPLVSLLALDCSMLQNFEALMALTNLAGISERLRQKIIKEKAVPKIEGYMFEEHDMVRAASTECMCNLALSTEVQKLYLAAESDRLKLLVLYSGE-DDERLRKAASGTLAVLTGEMPELCTRIPDTTS---HWLEILQALLLSESQDLRHRGVVIVMN-IMQADKSLAEKLMESEALEILSVLTKTDDPKQASVRKAAQRCLDLALEYGLIR 924

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Query:   95 TTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAV----AQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDI-----RFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
            ++  +E GN +FK+GD  +AL  Y   L   D   +  +  Y+N+S CYLK+  +        K+L +   D K+ +RR+ A   L +  +A  D +K   L+PKNK +Q+ +R++  QI+ +    +S   +V  MF LL  S      + K+  NL VL RE + +      D   LL+         +I +A R L  L      +T+ I    G +    ++ SS       A   L+ +   L++    R + +                       DEA+    ++ +   L+ LL    +  +S  GRDS + +LV+ VP K   N   + +L   + G  K+LEV       E+ P  T +         T M+ ++LL  +YDDL SDK+RE F  LC ++V        ME ++ A   + +L QGP + G+  L  SG++  ++ L  SE    Q++A++A++ A  K  +   I  + + + +E+YK + +D +++RALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N +   +  RWA EGLAYL+LDADVKE LV D++AL+ +  + K+     L+ + + L N TNSYD  +  P+M+ELAKYAKQH+PE H KD   F++ R+ +L++  +   L  + +    SP    A +E I+R+ L++V  ++ RG ++  GGGKAL+ L  ++TD GK+ AAQALAK+ IT NP IAFPG+R  EV+RPL+ LL ++ + LQNFE+LMALTNLA + +  R++IIKEK + ++E YMFEEH+M+R AS ECMCNL L  EV++ +L  E+DR+KLLVL   E +D  L KAASG LA+L+ ++     R  D  S   +W EI+QA++      ++HR V ++ N I+   +   E ++ S   EI+  L+K  D    +V   A+  L+  + + LI+
Sbjct:    5 SSALREEGNNHFKAGDVQQALTCYTKALKISDCPSESAV-LYRNRSACYLKLEDYTKAEEDATKSLDVDPGDIKARFRRAQALQKLGRLDQAFMDVQKCAQLEPKNKAFQDLLRQLGAQIQQKATQLSSTDSRVQQMFKLLLDSSAPIADRQKAAQNLVVLSREDAGAEQIFRNDGVKLLQNLLESKQEELILSALRTLVGLCTGHQSRTMAIVNELGMERLCGVMGSSASSVSLSACHLLQVMFEALTEGMKKRIRGK-----------------------DEAILPEPSRELRSMLRHLLDMLPASSVSGAGRDSAINLLVKQVPRKSVKNPDNSLSLWVIDQGLKKILEVAGTVAEVENGPPLTEN---------THMSCSVLLNKLYDDLKSDKERENFSKLCEEYVQHHFMSSSMERRLRAIQTVSVLLQGPSDVGNVTLELSGLMDSVISLCASEDIVQQQVAVEALIHAAGKAKRASFITANGVALLKELYKKSQNDRIRVRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNESLPPASRRWAIEGLAYLTLDADVKEDLVEDKKALQAMFELAKSEDKTVLFAVGSTLVNCTNSYDVEKPDPQMVELAKYAKQHVPEEHPKDGQPFVEQRVVKLLEAGVVSALVCMVK--QESPAMTEACRECIARVILALVERQEDRGLVVAQGGGKALLPLVSESTDRGKIKAAQALAKITITSNPEIAFPGERVYEVVRPLVSLLALDCSMLQNFEALMALTNLAGISERLRQKIIKEKAVPKIEGYMFEEHDMVRAASTECMCNLALSTEVQKLYLAAESDRLKLLVLYSGE-DDERLRKAASGTLAVLTGEMPELCTRIPDTTS---HWLEILQALLLSESQDLRHRGVVIVMN-IMQADKSLAEKLMESEALEILSVLTKTDDPKQASVRKAAQRCLDLALEYGLIR 924

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BLAST of Protein unc-45 homolog A vs. Ensembl Zebrafish
Match: unc45a (unc-45 myosin chaperone A [Source:ZFIN;Acc:ZDB-GENE-050417-158])

HSP 1 Score: 90.8929 bits (224), Expect = 5.455e-20
Identity = 53/168 (31.55%), Postives = 87/168 (51.79%), Query Frame = 2

Query:   95 TTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS 598
            ++  +E GN +FK+GD  +AL  Y   L   D   +  +  Y+N+S CYLK+  +        K+L +   D K+ +RR+ A   L +  +A  D +K   L+PKNK +Q+ +R++  QI+ +    +S   +V  MF LL  S      + K+  NL VL RE + +
Sbjct:    5 SSALREEGNNHFKAGDVQQALTCYTKALKISDCPSESAV-LYRNRSACYLKLEDYTKAEEDATKSLDVDPGDIKARFRRAQALQKLGRLDQAFMDVQKCAQLEPKNKAFQDLLRQLGAQIQQKATQLSSTDSRVQQMFKLLLDSSAPIADRQKAAQNLVVLSREDAGA 171

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Zebrafish
Match: unc45a (unc-45 myosin chaperone A [Source:ZFIN;Acc:ZDB-GENE-050417-158])

HSP 1 Score: 90.8929 bits (224), Expect = 6.866e-20
Identity = 53/168 (31.55%), Postives = 87/168 (51.79%), Query Frame = 2

Query:   95 TTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS 598
            ++  +E GN +FK+GD  +AL  Y   L   D   +  +  Y+N+S CYLK+  +        K+L +   D K+ +RR+ A   L +  +A  D +K   L+PKNK +Q+ +R++  QI+ +    +S   +V  MF LL  S      + K+  NL VL RE + +
Sbjct:    5 SSALREEGNNHFKAGDVQQALTCYTKALKISDCPSESAV-LYRNRSACYLKLEDYTKAEEDATKSLDVDPGDIKARFRRAQALQKLGRLDQAFMDVQKCAQLEPKNKAFQDLLRQLGAQIQQKATQLSSTDSRVQQMFKLLLDSSAPIADRQKAAQNLVVLSREDAGA 171

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Xenopus
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:493552])

HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0
Identity = 359/959 (37.43%), Postives = 545/959 (56.83%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLN-TKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTD-DMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVT-CAEESLEALVNHKLIK 2947
             +E GN++FK+GD++ AL  Y   ++ T D  D  K   ++N+S CYLK+  F        KA+++   D K+L+RRS A   L +  +A  D ++ + L+PKNK++QE +R +  + + +V   +S   +V+ MF +L   +  D + + K+  NL VL RE + +  I+      +LL+      P ++I AA R L  L      + + I    G +    ++     +    A   L  +   L +   KD+R K             ++   P          +Q +   +  LL+      +SA GR+S L +L++ VP K     +   TL   + G  K+LEVG          S       +  T  T+M+ ++LL  ++DDL  D +RE F  LC D+V  L     M+ K+ +   +  L QGP EAG+  L  +GI++ ++ L  SE    Q++A++A++ A  K  +   I  + + + ++IYK   +DA++IRALVG+CKLGS GG D S+   AEGS ++LAK CRK+L    N   + S  RWA EGLAYL+ DADVKE  V D+ AL+ +  + K+     L+ + + L N TNSYD+  I P+MLELAKYAKQH+PE H KD   F++TR+ +L+   +   L  + +  + SP   ++SKELISR++L++V   + RG ++  GGGKALI LAL+ TD GK  AAQALAK++IT NP IAFPG+R  EV+RPL+ LL +  TGLQNFE+LMALTNLA + +  R +II EK  S +E YMFEEHEM+R A+ ECMCN+ +  EV++ FL E +DR+KL+VL   E +D  L +AASG LA+L+S + +   ++++V  +W EI+QA++   +  +QHR   ++ NM+    +E  E ++ S M EI+  L+K  +E  K  VT  A+E L   V + LIK
Sbjct:   14 LREDGNKHFKAGDYEAALSCYTKAISLTSDKAD--KAVLHRNRSACYLKLDDFTKAEEDASKAIEVDGGDVKALFRRSQALEKLGRVDQAIIDLRRCLTLEPKNKVFQEAVRNLGIRAQEKVRLLSSTDSRVDQMFQILLDPEEKDAEKQQKAAQNLIVLAREDAGAEKIFQSDGIRLLLRMMDTKKP-DMILAALRTLVGLCTDHQSRAMAILSAVGIEKLCAVMAMDDEQISVAACSVLHAVFDSLKEGMKKDFRGK-----------EAAIVLDP----------SQELKSVIHNLLEMLTRPSVSAHGRESALNLLMKVVPRKSFRDPDNGMTLWVIDTGLKKILEVGG---------SLVEFPGSLSVTESTRMSASVLLNKLFDDLKCDAERENFHKLCEDYVRSLFEGHGMDGKLRSIQTVSCLLQGPSEAGNRTLELTGIMESIISLCASEREIDQQVAVEALIYAAGKAKRASFITANGVALLKDIYKKNENDAIRIRALVGLCKLGSAGGTDFSMKQFAEGSTIKLAKQCRKWL---CNETIESSTRRWAVEGLAYLTFDADVKEEFVEDKTALQAMFTLAKSQDKTVLFAVASTLVNCTNSYDREAIDPQMLELAKYAKQHVPEEHPKDKKEFVETRVHKLLAAGVVSALVCMVK--NESPALTDSSKELISRVFLALVDKAEDRGNVVAQGGGKALIPLALEGTDVGKTKAAQALAKISITSNPEIAFPGERIYEVVRPLVSLLHLNRTGLQNFEALMALTNLAGISERLRSKIISEKAASMIEGYMFEEHEMIRVAATECMCNMAMSKEVQDLFLVEGSDRLKLMVLYSGE-DDERLRRAASGTLAMLTSLEPKLCTRITQVTVHWMEILQALLLSENIDLQHRGGVVVLNMM-TADKEVAEKMMESEMLEILSVLAKNEEEEKKKAVTSVAKECLAKAVEYGLIK 932

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Xenopus
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:493552])

HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0
Identity = 359/957 (37.51%), Postives = 544/957 (56.84%), Query Frame = 2

Query:  110 ELGNEYFKSGDFDKALEMYINGLN-TKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTD-DMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVT-CAEESLEALVNHKLIK 2947
            E GN++FK+GD++ AL  Y   ++ T D  D  K   ++N+S CYLK+  F        KA+++   D K+L+RRS A   L +  +A  D ++ + L+PKNK++QE +R +  + + +V   +S   +V+ MF +L   +  D + + K+  NL VL RE + +  I+      +LL+      P ++I AA R L  L      + + I    G +    ++     +    A   L  +   L +   KD+R K             ++   P          +Q +   +  LL+      +SA GR+S L +L++ VP K     +   TL   + G  K+LEVG          S       +  T  T+M+ ++LL  ++DDL  D +RE F  LC D+V  L     M+ K+ +   +  L QGP EAG+  L  +GI++ ++ L  SE    Q++A++A++ A  K  +   I  + + + ++IYK   +DA++IRALVG+CKLGS GG D S+   AEGS ++LAK CRK+L    N   + S  RWA EGLAYL+ DADVKE  V D+ AL+ +  + K+     L+ + + L N TNSYD+  I P+MLELAKYAKQH+PE H KD   F++TR+ +L+   +   L  + +  + SP   ++SKELISR++L++V   + RG ++  GGGKALI LAL+ TD GK  AAQALAK++IT NP IAFPG+R  EV+RPL+ LL +  TGLQNFE+LMALTNLA + +  R +II EK  S +E YMFEEHEM+R A+ ECMCN+ +  EV++ FL E +DR+KL+VL   E +D  L +AASG LA+L+S + +   ++++V  +W EI+QA++   +  +QHR   ++ NM+    +E  E ++ S M EI+  L+K  +E  K  VT  A+E L   V + LIK
Sbjct:    9 EDGNKHFKAGDYEAALSCYTKAISLTSDKAD--KAVLHRNRSACYLKLDDFTKAEEDASKAIEVDGGDVKALFRRSQALEKLGRVDQAIIDLRRCLTLEPKNKVFQEAVRNLGIRAQEKVRLLSSTDSRVDQMFQILLDPEEKDAEKQQKAAQNLIVLAREDAGAEKIFQSDGIRLLLRMMDTKKP-DMILAALRTLVGLCTDHQSRAMAILSAVGIEKLCAVMAMDDEQISVAACSVLHAVFDSLKEGMKKDFRGK-----------EAAIVLDP----------SQELKSVIHNLLEMLTRPSVSAHGRESALNLLMKVVPRKSFRDPDNGMTLWVIDTGLKKILEVGG---------SLVEFPGSLSVTESTRMSASVLLNKLFDDLKCDAERENFHKLCEDYVRSLFEGHGMDGKLRSIQTVSCLLQGPSEAGNRTLELTGIMESIISLCASEREIDQQVAVEALIYAAGKAKRASFITANGVALLKDIYKKNENDAIRIRALVGLCKLGSAGGTDFSMKQFAEGSTIKLAKQCRKWL---CNETIESSTRRWAVEGLAYLTFDADVKEEFVEDKTALQAMFTLAKSQDKTVLFAVASTLVNCTNSYDREAIDPQMLELAKYAKQHVPEEHPKDKKEFVETRVHKLLAAGVVSALVCMVK--NESPALTDSSKELISRVFLALVDKAEDRGNVVAQGGGKALIPLALEGTDVGKTKAAQALAKISITSNPEIAFPGERIYEVVRPLVSLLHLNRTGLQNFEALMALTNLAGISERLRSKIISEKAASMIEGYMFEEHEMIRVAATECMCNMAMSKEVQDLFLVEGSDRLKLMVLYSGE-DDERLRRAASGTLAMLTSLEPKLCTRITQVTVHWMEILQALLLSENIDLQHRGGVVVLNMM-TADKEVAEKMMESEMLEILSVLAKNEEEEKKKAVTSVAKECLAKAVEYGLIK 925

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Xenopus
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:493552])

HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0
Identity = 358/955 (37.49%), Postives = 543/955 (56.86%), Query Frame = 2

Query:  116 GNEYFKSGDFDKALEMYINGLN-TKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTD-DMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVT-CAEESLEALVNHKLIK 2947
            GN++FK+GD++ AL  Y   ++ T D  D  K   ++N+S CYLK+  F        KA+++   D K+L+RRS A   L +  +A  D ++ + L+PKNK++QE +R +  + + +V   +S   +V+ MF +L   +  D + + K+  NL VL RE + +  I+      +LL+      P ++I AA R L  L      + + I    G +    ++     +    A   L  +   L +   KD+R K             ++   P          +Q +   +  LL+      +SA GR+S L +L++ VP K     +   TL   + G  K+LEVG          S       +  T  T+M+ ++LL  ++DDL  D +RE F  LC D+V  L     M+ K+ +   +  L QGP EAG+  L  +GI++ ++ L  SE    Q++A++A++ A  K  +   I  + + + ++IYK   +DA++IRALVG+CKLGS GG D S+   AEGS ++LAK CRK+L    N   + S  RWA EGLAYL+ DADVKE  V D+ AL+ +  + K+     L+ + + L N TNSYD+  I P+MLELAKYAKQH+PE H KD   F++TR+ +L+   +   L  + +  + SP   ++SKELISR++L++V   + RG ++  GGGKALI LAL+ TD GK  AAQALAK++IT NP IAFPG+R  EV+RPL+ LL +  TGLQNFE+LMALTNLA + +  R +II EK  S +E YMFEEHEM+R A+ ECMCN+ +  EV++ FL E +DR+KL+VL   E +D  L +AASG LA+L+S + +   ++++V  +W EI+QA++   +  +QHR   ++ NM+    +E  E ++ S M EI+  L+K  +E  K  VT  A+E L   V + LIK
Sbjct:    7 GNKHFKAGDYEAALSCYTKAISLTSDKAD--KAVLHRNRSACYLKLDDFTKAEEDASKAIEVDGGDVKALFRRSQALEKLGRVDQAIIDLRRCLTLEPKNKVFQEAVRNLGIRAQEKVRLLSSTDSRVDQMFQILLDPEEKDAEKQQKAAQNLIVLAREDAGAEKIFQSDGIRLLLRMMDTKKP-DMILAALRTLVGLCTDHQSRAMAILSAVGIEKLCAVMAMDDEQISVAACSVLHAVFDSLKEGMKKDFRGK-----------EAAIVLDP----------SQELKSVIHNLLEMLTRPSVSAHGRESALNLLMKVVPRKSFRDPDNGMTLWVIDTGLKKILEVGG---------SLVEFPGSLSVTESTRMSASVLLNKLFDDLKCDAERENFHKLCEDYVRSLFEGHGMDGKLRSIQTVSCLLQGPSEAGNRTLELTGIMESIISLCASEREIDQQVAVEALIYAAGKAKRASFITANGVALLKDIYKKNENDAIRIRALVGLCKLGSAGGTDFSMKQFAEGSTIKLAKQCRKWL---CNETIESSTRRWAVEGLAYLTFDADVKEEFVEDKTALQAMFTLAKSQDKTVLFAVASTLVNCTNSYDREAIDPQMLELAKYAKQHVPEEHPKDKKEFVETRVHKLLAAGVVSALVCMVK--NESPALTDSSKELISRVFLALVDKAEDRGNVVAQGGGKALIPLALEGTDVGKTKAAQALAKISITSNPEIAFPGERIYEVVRPLVSLLHLNRTGLQNFEALMALTNLAGISERLRSKIISEKAASMIEGYMFEEHEMIRVAATECMCNMAMSKEVQDLFLVEGSDRLKLMVLYSGE-DDERLRRAASGTLAMLTSLEPKLCTRITQVTVHWMEILQALLLSENIDLQHRGGVVVLNMM-TADKEVAEKMMESEMLEILSVLAKNEEEEKKKAVTSVAKECLAKAVEYGLIK 921

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Xenopus
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:493552])

HSP 1 Score: 572.778 bits (1475), Expect = 0.000e+0
Identity = 358/959 (37.33%), Postives = 548/959 (57.14%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLN-TKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTD-DMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVT-CAEESLEALVNHKLIK 2947
             +E GN++FK+GD++ AL  Y   ++ T D  D  K   ++N+S CYLK+++    +SA   ++++   D K+L+RRS A   L +  +A  D ++ + L+PKNK++QE +R +  + + +V   +S   +V+ MF +L   +  D + + K+  NL VL RE + +  I+      +LL+      P ++I AA R L  L      + + I    G +    ++     +    A   L  +   L +   KD+R K             ++   P          +Q +   +  LL+      +SA GR+S L +L++ VP K     +   TL   + G  K+LEVG          S       +  T  T+M+ ++LL  ++DDL  D +RE F  LC D+V  L     M+ K+ +   +  L QGP EAG+  L  +GI++ ++ L  SE    Q++A++A++ A  K  +   I  + + + ++IYK   +DA++IRALVG+CKLGS GG D S+   AEGS ++LAK CRK+L    N   + S  RWA EGLAYL+ DADVKE  V D+ AL+ +  + K+     L+ + + L N TNSYD+  I P+MLELAKYAKQH+PE H KD   F++TR+ +L+   +   L  + +  + SP   ++SKELISR++L++V   + RG ++  GGGKALI LAL+ TD GK  AAQALAK++IT NP IAFPG+R  EV+RPL+ LL +  TGLQNFE+LMALTNLA + +  R +II EK  S +E YMFEEHEM+R A+ ECMCN+ +  EV++ FL E +DR+KL+VL   E +D  L +AASG LA+L+S + +   ++++V  +W EI+QA++   +  +QHR   ++ NM+    +E  E ++ S M EI+  L+K  +E  K  VT  A+E L   V + LIK
Sbjct:    7 LREDGNKHFKAGDYEAALSCYTKAISLTSDKAD--KAVLHRNRSACYLKLVRSGQALSA--DSIEVDGGDVKALFRRSQALEKLGRVDQAIIDLRRCLTLEPKNKVFQEAVRNLGIRAQEKVRLLSSTDSRVDQMFQILLDPEEKDAEKQQKAAQNLIVLAREDAGAEKIFQSDGIRLLLRMMDTKKP-DMILAALRTLVGLCTDHQSRAMAILSAVGIEKLCAVMAMDDEQISVAACSVLHAVFDSLKEGMKKDFRGK-----------EAAIVLDP----------SQELKSVIHNLLEMLTRPSVSAHGRESALNLLMKVVPRKSFRDPDNGMTLWVIDTGLKKILEVGG---------SLVEFPGSLSVTESTRMSASVLLNKLFDDLKCDAERENFHKLCEDYVRSLFEGHGMDGKLRSIQTVSCLLQGPSEAGNRTLELTGIMESIISLCASEREIDQQVAVEALIYAAGKAKRASFITANGVALLKDIYKKNENDAIRIRALVGLCKLGSAGGTDFSMKQFAEGSTIKLAKQCRKWL---CNETIESSTRRWAVEGLAYLTFDADVKEEFVEDKTALQAMFTLAKSQDKTVLFAVASTLVNCTNSYDREAIDPQMLELAKYAKQHVPEEHPKDKKEFVETRVHKLLAAGVVSALVCMVK--NESPALTDSSKELISRVFLALVDKAEDRGNVVAQGGGKALIPLALEGTDVGKTKAAQALAKISITSNPEIAFPGERIYEVVRPLVSLLHLNRTGLQNFEALMALTNLAGISERLRSKIISEKAASMIEGYMFEEHEMIRVAATECMCNMAMSKEVQDLFLVEGSDRLKLMVLYSGE-DDERLRRAASGTLAMLTSLEPKLCTRITQVTVHWMEILQALLLSENIDLQHRGGVVVLNMM-TADKEVAEKMMESEMLEILSVLAKNEEEEKKKAVTSVAKECLAKAVEYGLIK 923

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Xenopus
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:493552])

HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0
Identity = 361/962 (37.53%), Postives = 552/962 (57.38%), Query Frame = 2

Query:   92 MTTHF-KELGNEYFKSGDFDKALEMYINGLN-TKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTD-DMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVT-CAEESLEALVNHKLIK 2947
            +TT+  +E GN++FK+GD++ AL  Y   ++ T D  D  K   ++N+S CYLK+  F        KA+++   D K+L+RRS A   L +  +A  D ++ + L+PKNK++QE +R +  + + +V   +S   +V+ MF +L   +  D + + K+  NL VL RE + +  I+      +LL+      P ++I AA R L  L     +    + KL       +   S     C +     +++  G+   KD+R K             ++   P          +Q +   +  LL+      +SA GR+S L +L++ VP K     +   TL   + G  K+LEVG          S       +  T  T+M+ ++LL  ++DDL  D +RE F  LC D+V  L     M+ K+ +   +  L QGP EAG+  L  +GI++ ++ L  SE    Q++A++A++ A  K  +   I  + + + ++IYK   +DA++IRALVG+CKLGS GG D S+   AEGS ++LAK CRK+L    N   + S  RWA EGLAYL+ DADVKE  V D+ AL+ +  ++++ T+  L+ + + L N TNSYD+  I P+MLELAKYAKQH+PE H KD   F++TR+ +L+   +   L  + +  + SP   ++SKELISR++L++V   + RG ++  GGGKALI LAL+ TD GK  AAQALAK++IT NP IAFPG+R  EV+RPL+ LL +  TGLQNFE+LMALTNLA + +  R +II EK  S +E YMFEEHEM+R A+ ECMCN+ +  EV++ FL E +DR+KL+VL   E +D  L +AASG LA+L+S + +   ++++V  +W EI+QA++   +  +QHR   ++ NM+    +E  E ++ S M EI+  L+K  +E  K  VT  A+E L   V + LIK
Sbjct:   69 LTTYIHREDGNKHFKAGDYEAALSCYTKAISLTSDKAD--KAVLHRNRSACYLKLDDFTKAEEDASKAIEVDGGDVKALFRRSQALEKLGRVDQAIIDLRRCLTLEPKNKVFQEAVRNLGIRAQEKVRLLSSTDSRVDQMFQILLDPEEKDAEKQQKAAQNLIVLAREDAGAEKIFQSDGIRLLLRMMDTKKP-DMILAALRTLVGL---CTDHQSRVKKLCAVMAMDDEQISVAA--CSVLHAVFDSLKEGMK--KDFRGK-----------EAAIVLDP----------SQELKSVIHNLLEMLTRPSVSAHGRESALNLLMKVVPRKSFRDPDNGMTLWVIDTGLKKILEVGG---------SLVEFPGSLSVTESTRMSASVLLNKLFDDLKCDAERENFHKLCEDYVRSLFEGHGMDGKLRSIQTVSCLLQGPSEAGNRTLELTGIMESIISLCASEREIDQQVAVEALIYAAGKAKRASFITANGVALLKDIYKKNENDAIRIRALVGLCKLGSAGGTDFSMKQFAEGSTIKLAKQCRKWL---CNETIESSTRRWAVEGLAYLTFDADVKEEFVEDKTALQAMFTLSQDKTV--LFAVASTLVNCTNSYDREAIDPQMLELAKYAKQHVPEEHPKDKKEFVETRVHKLLAAGVVSALVCMVK--NESPALTDSSKELISRVFLALVDKAEDRGNVVAQGGGKALIPLALEGTDVGKTKAAQALAKISITSNPEIAFPGERIYEVVRPLVSLLHLNRTGLQNFEALMALTNLAGISERLRSKIISEKAASMIEGYMFEEHEMIRVAATECMCNMAMSKEVQDLFLVEGSDRLKLMVLYSGE-DDERLRRAASGTLAMLTSLEPKLCTRITQVTVHWMEILQALLLSENIDLQHRGGVVVLNMM-TADKEVAEKMMESEMLEILSVLAKNEEEEKKKAVTSVAKECLAKAVEYGLIK 981

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Mouse
Match: Unc45a (unc-45 myosin chaperone A [Source:MGI Symbol;Acc:MGI:2142246])

HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0
Identity = 341/958 (35.59%), Postives = 535/958 (55.85%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGS-DAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD++ AL  Y   L+      D+ +  ++N++ C+LK+  +    S   KA++    D K+LYRRS A   L +  +A  D K+ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +      +   LL+        +++ AA R L  +      +T+    + G +   +++          A   L+ I   L +   K +R K            G++   P          A+ +   + +LL+      +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG          S  +    +  T  ++M+ +ILL+ ++DDL  D +RE F  LC +++ +      +  K+ A   +  L QGP +AG+  L  SG+++ ++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK    D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V DE AL+ L  ++++     L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   N+ +EL+SR++L++V   + RG ++  GGGKAL+ LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRA+ ECMCNL +  EV++ F  + NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++   +  +QHR   ++ NM+   S+E    ++ S + EI+  L+K  +     V   A   LE  V ++LI+P
Sbjct:   23 QLRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAI-LHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTEETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVIFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLINSLLELLTEVGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGG---------SLQDAAGELTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRNWFEGHGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEREEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERSVLFAVGSALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMTCMVK--TESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDEL-LRRAAAGGLAMLTSMRPALCSRIPQVTTHWLEILQALLLSPNQELQHRGTVVVLNMM-QSSKEIAGTLMESEVLEILSVLAKGEESP---VTRAAAACLEKAVEYRLIQP 939

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BLAST of Protein unc-45 homolog A vs. Ensembl Mouse
Match: Unc45a (unc-45 myosin chaperone A [Source:MGI Symbol;Acc:MGI:2142246])

HSP 1 Score: 555.058 bits (1429), Expect = 2.789e-180
Identity = 341/958 (35.59%), Postives = 535/958 (55.85%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGS-DAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD++ AL  Y   L+      D+ +  ++N++ C+LK+  +    S   KA++    D K+LYRRS A   L +  +A  D K+ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +      +   LL+        +++ AA R L  +      +T+    + G +   +++          A   L+ I   L +   K +R K            G++   P          A+ +   + +LL+      +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG          S  +    +  T  ++M+ +ILL+ ++DDL  D +RE F  LC +++ +      +  K+ A   +  L QGP +AG+  L  SG+++ ++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK    D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V DE AL+ L  ++++     L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   N+ +EL+SR++L++V   + RG ++  GGGKAL+ LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRA+ ECMCNL +  EV++ F  + NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++   +  +QHR   ++ NM+   S+E    ++ S + EI+  L+K  +     V   A   LE  V ++LI+P
Sbjct:  167 QLRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAI-LHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTEETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVIFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLINSLLELLTEVGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGG---------SLQDAAGELTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRNWFEGHGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEREEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERSVLFAVGSALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMTCMVK--TESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDEL-LRRAAAGGLAMLTSMRPALCSRIPQVTTHWLEILQALLLSPNQELQHRGTVVVLNMM-QSSKEIAGTLMESEVLEILSVLAKGEESP---VTRAAAACLEKAVEYRLIQP 1083

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BLAST of Protein unc-45 homolog A vs. Ensembl Mouse
Match: Unc45b (unc-45 myosin chaperone B [Source:MGI Symbol;Acc:MGI:2443377])

HSP 1 Score: 526.939 bits (1356), Expect = 2.381e-171
Identity = 341/963 (35.41%), Postives = 525/963 (54.52%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL--NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQT---LLQACNSKKLSATGRDSILEILVRFVPSKEGI--NWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL-TDETMKNVVTCAEESLEALVNHKLIKPI 2953
              KE GN +F+  D+  A + Y   L    +T D+ L    Y+N++ C LKM  +    S   +A+ I+  D K+LYRR  A  +L K  +A  D ++   L+P+N+ +QE +R +   I+ Q+    S   +V  MF +L   +   D + K+ NNL VL RE + +  I+      +LL+      P  ++ AA R LS +      +   I          +++     E        L+ I+  LS  +D RE                      R + +  V     D  Q    LL    SKK+S  GRD  L +L + VP K+    + ++T+   + G  K+L+V          P   + + L D T   +M  +IL+  +YDDL  D +R+ FR +C +++      + M+  V A   +  + QGPF+ G+ +LG  G+++ ++ L  SE  + Q +A++A++ A TK  +   II + + + ++IYKT  ++ +KIR LVG+CKLGS GG D  +   AEGS  +LAK CRK+L    N   D    RWA EGLAYL+LDADVK+  V D  AL+ +  + K +    LY +   L N TNSYD  E++PE+++LAK++KQH+PE H KD   F+  R++ L+K  +   L  + + ADS+  + + +KEL++R++L++    + RG I+  GGGKALI LAL+ TD GKV AA  LAK+A   NP IAFPG+R  EV+RPL+ LL  +  GLQN+E+L+ LTNL+   D  R++I KEK L  +E YMFE H+ LR+A+ ECMCN++L  EV+ERFL + NDR+KL+VLLC E +D  L  AA+G LA+L+ +  +   K+++V   W EI+Q +      ++QHR + +  N++ +   E    +V S + EI+  + K   DE    VV  A E L   +++  IKP+
Sbjct:    8 QLKEEGNRHFQLQDYKAATKSYSQALK---LTKDKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLNENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMNTQRP-ELLLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCNLLQAIIDSLSG-EDKRE---------------------HRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKILKVVG------QVPDLPSCLPLTDNT---RMLASILINKLYDDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWL---CNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKTSDKTILYSVANTLVNCTNSYDVKEVVPELVQLAKFSKQHVPEEHPKDKKDFVDLRVKRLLKAGVISALACMVK-ADSAILT-DQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKEKALPDIENYMFENHDQLRQAATECMCNMVLNKEVQERFLADGNDRLKLVVLLCGE-DDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLHDQLSVQHRGLVIAHNLL-SADAELARKLVESELLEILTVVGKQEPDEKRAAVVQTARECLIKCMDYGFIKPV 928

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BLAST of Protein unc-45 homolog A vs. Ensembl Mouse
Match: Unc45b (unc-45 myosin chaperone B [Source:MGI Symbol;Acc:MGI:2443377])

HSP 1 Score: 523.857 bits (1348), Expect = 3.556e-170
Identity = 342/965 (35.44%), Postives = 526/965 (54.51%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL--NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQT---LLQACNSKKLSATGRDSILEILVRFVPSKEGI--NWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIE--CLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL-TDETMKNVVTCAEESLEALVNHKLIKPI 2953
              KE GN +F+  D+  A + Y   L    +T D+ L    Y+N++ C LKM  +    S   +A+ I+  D K+LYRR  A  +L K  +A  D ++   L+P+N+ +QE +R +   I+ Q+    S   +V  MF +L   +   D + K+ NNL VL RE + +  I+      +LL+      P  ++ AA R LS +      +   I          +++     E        L+ I+  LS  +D RE                      R + +  V     D  Q    LL    SKK+S  GRD  L +L + VP K+    + ++T+   + G  K+L+V          P   + + L D T   +M  +IL+  +YDDL  D +R+ FR +C +++      + M+  V A   +  + QGPF+ G+ +LG  G+++ ++ L  SE  + Q +A++A++ A TK  +   II + + + ++IYKT  ++ +KIR LVG+CKLGS GG D  +   AEGS  +LAK CRK+L    N   D    RWA EGLAYL+LDADVK+  V D  AL+ +  + K  T +   LY +   L N TNSYD  E++PE+++LAK++KQH+PE H KD   F+  R++ L+K  +   L  + + ADS+  + + +KEL++R++L++    + RG I+  GGGKALI LAL+ TD GKV AA  LAK+A   NP IAFPG+R  EV+RPL+ LL  +  GLQN+E+L+ LTNL+   D  R++I KEK L  +E YMFE H+ LR+A+ ECMCN++L  EV+ERFL + NDR+KL+VLLC E +D  L  AA+G LA+L+ +  +   K+++V   W EI+Q +      ++QHR + +  N++ +   E    +V S + EI+  + K   DE    VV  A E L   +++  IKP+
Sbjct:    8 QLKEEGNRHFQLQDYKAATKSYSQALK---LTKDKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLNENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMNTQRP-ELLLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCNLLQAIIDSLSG-EDKRE---------------------HRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKILKVVG------QVPDLPSCLPLTDNT---RMLASILINKLYDDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWL---CNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKARTSDKTILYSVANTLVNCTNSYDVKEVVPELVQLAKFSKQHVPEEHPKDKKDFVDLRVKRLLKAGVISALACMVK-ADSAILT-DQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKEKALPDIENYMFENHDQLRQAATECMCNMVLNKEVQERFLADGNDRLKLVVLLCGE-DDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLHDQLSVQHRGLVIAHNLL-SADAELARKLVESELLEILTVVGKQEPDEKRAAVVQTARECLIKCMDYGFIKPV 930

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Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL--NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQT---LLQACNSKKLSATGRDSILEILVRFVPSKEGI--NWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIE--CLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL-TDETMKNVVTCAEESLEALVNHKLIKPI 2953
              KE GN +F+  D+  A + Y   L    +T D+ L    Y+N++ C LKM  +    S   +A+ I+  D K+LYRR  A  +L K  +A  D ++   L+P+N+ +QE +R +   I+ Q+    S   +V  MF +L   +   D + K+ NNL VL RE + +  I+      +LL+      P  ++ AA R LS +      +   I          +++     E        L+ I+  LS  +D RE                      R + +  V     D  Q    LL    SKK+S  GRD  L +L + VP K+    + ++T+   + G  K+L+V          P   + + L D T   +M  +IL+  +YDDL  D +R+ FR +C +++      + M+  V A   +  + QGPF+ G+ +LG  G+++ ++ L  SE  + Q +A++A++ A TK  +   II + + + ++IYKT  ++ +KIR LVG+CKLGS GG D  +   AEGS  +LAK CRK+L    N   D    RWA EGLAYL+LDADVK+  V D  AL+ +  + K  T +   LY +   L N TNSYD  E++PE+++LAK++KQH+PE H KD   F+  R++ L+K  +   L  + + ADS+  + + +KEL++R++L++    + RG I+  GGGKALI LAL+ TD GKV AA  LAK+A   NP IAFPG+R  EV+RPL+ LL  +  GLQN+E+L+ LTNL+   D  R++I KEK L  +E YMFE H+ LR+A+ ECMCN++L  EV+ERFL + NDR+KL+VLLC E +D  L  AA+G LA+L+ +  +   K+++V   W EI+Q +      ++QHR + +  N++ +   E    +V S + EI+  + K   DE    VV  A E L   +++  IKP+
Sbjct:    8 QLKEEGNRHFQLQDYKAATKSYSQALK---LTKDKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLNENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMNTQRP-ELLLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCNLLQAIIDSLSG-EDKRE---------------------HRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKILKVVG------QVPDLPSCLPLTDNT---RMLASILINKLYDDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWL---CNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKARTSDKTILYSVANTLVNCTNSYDVKEVVPELVQLAKFSKQHVPEEHPKDKKDFVDLRVKRLLKAGVISALACMVK-ADSAILT-DQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKEKALPDIENYMFENHDQLRQAATECMCNMVLNKEVQERFLADGNDRLKLVVLLCGE-DDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLHDQLSVQHRGLVIAHNLL-SADAELARKLVESELLEILTVVGKQEPDEKRAAVVQTARECLIKCMDYGFIKPV 930

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BLAST of Protein unc-45 homolog A vs. UniProt/SwissProt
Match: sp|Q32PZ3|UN45A_RAT (Protein unc-45 homolog A OS=Rattus norvegicus OX=10116 GN=Unc45a PE=2 SV=1)

HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0
Identity = 342/958 (35.70%), Postives = 537/958 (56.05%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGS-DAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD++ AL  Y   L+      D+ +  ++N++ C+LK+  +    S   KA++    D K+LYRRS A   L +  +A  D K+ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +      +   LL+        +++ AA R L  +      +T+    + G +   +++          A   L+ +   L +   K +R K            G++   P          A+ +   +  LL+      +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG       S P     +++   T  ++M+ +ILL+ ++DDL  D +RE F  LC +++      + +  K+ A   +  L QGP +AG+  L  SG+++ ++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK    D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V DE AL+ L  ++++     L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   N+ +EL+SR++L++V   + RG ++  GGGKAL+ LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRA+ ECMCNL +  EV++ F  + NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++   +P +QHR   ++ NM+   S+E    ++ S + EI+  L+K  +     V   A   LE  V ++LI+P
Sbjct:   23 ELRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAI-LHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTGETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVMFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLISNLLELLTEIGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGG------SVPEAAGELTV---TANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVALLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERSVLFAVGSALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMTCMVK--TESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDEL-LRRAAAGGLAMLTSMRPSLCSRIPQVTTHWLEILQALLLSPNPELQHRGTVVVLNMM-ESSKEIASTLMESEVLEILSVLAKGEESP---VTRAAAACLEKAVEYRLIQP 939

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BLAST of Protein unc-45 homolog A vs. UniProt/SwissProt
Match: sp|Q5RAP0|UN45A_PONAB (Protein unc-45 homolog A OS=Pongo abelii OX=9601 GN=UNC45A PE=2 SV=1)

HSP 1 Score: 560.836 bits (1444), Expect = 0.000e+0
Identity = 346/958 (36.12%), Postives = 536/958 (55.95%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD+  AL  Y   L   D T  ++   ++N++ CYLK+  +D   +   KA++    D K+LYRRS A   L +  +A  D ++ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +      +   LL+        +++ AA R L  +      +T+    + G +   +++          A   L+ +   L +   K +R K            G++   P          A+ +   +  LL       +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG +    +  P +      +  T  ++M+ +ILL+ ++DDL  D +RE F  LC +++        +  K+ A   +  L QGP +AG+  L  SG+++G++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK +  D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V D  AL+ L  ++++     L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   ++ +EL+SRI+L++V   + RG ++  GGG+ALI LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRAS ECMCNL +  EV++ F  E NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++  ++  +QHR   ++ NM V  SRE    ++ S M EI+  L+K  D +   V   A   L+  V + LI+P
Sbjct:    8 QLRKEGNELFKCGDYGGALAAYTQALGL-DATPQDQAVLHRNRAACYLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAGAEKTLRSNGVQLLQRLLDTGETDLMLAALRTLVGICSEHQSRTVATLSILGTRRVVSILGVESQSVSLAACHLLQVMFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLISNLLDLLTEVGVSGQGRDNALTLLIKAVPRKSLKDPNNSLTLWVIDQGLKKILEVGGSL---QDPPGE------LAVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIKSWFEGRGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMEGVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKRSEKDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDAAALKALFQLSRSEERSVLFAVASALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMVYMVK--TESPVLTSSCRELLSRIFLALVEEVEDRGTVVAQGGGRALIPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLNCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRASTECMCNLAMSKEVQDLFEAEGNDRLKLLVLYSGEDDEL-LQRAAAGGLAMLTSMRPTLCSRIPQVTTHWLEILQALLLSSNQELQHRGAVVVLNM-VEASREIASTLMESEMMEILSVLAK-GDHS--PVTRAAAACLDKAVEYGLIQP 924

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BLAST of Protein unc-45 homolog A vs. UniProt/SwissProt
Match: sp|Q6DGE9|UN45B_DANRE (Protein unc-45 homolog B OS=Danio rerio OX=7955 GN=unc45b PE=1 SV=2)

HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0
Identity = 341/961 (35.48%), Postives = 542/961 (56.40%), Query Frame = 2

Query:   95 TTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNY-YKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVP--SKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMK-NVVTCAEESLEALVNHKLIKPI 2953
            +   KE GN++F++G+ D+A++ Y   + T    D + L   Y+N+S C+LK   +    S   KA+ +   D K+LYRR  AF  L K   A  D ++   ++PKNK + E +R +  +I+ +++   S   +V  MF++L   +   + + K+ NNL VL RE + +  I+ +    +L++      P  +I AA R LS +      +   I    G     +++     E         + +   LS   D R                 N+   +   +D +  + + D L  LL+   SK +S  GRD  L +L + VP  +K+  + +K L   + G  K+L+V          P   + + +   T  T++  ++LL+ +YDDL  D +R++FRD+C D++        M+  + A N +  + QGPF+ G+ + G+ G+++ ++ L  SE    Q +A++A++ A TK  K    I + + + +E+YK T ++ +KIRALVG+CKLGS GG D S+   AEGS  +LAK CRK+L    N   D    +WA EGLAYL+ DADVK+    DE A+R +  +TK+     LY +   L N TNSYDK EI+PEM++LAK++KQH+PE H KD   FI  R++ L+K  ++  L  + +  +S    Q  +KE+++R++L++    + RG I+  GGGKALI LAL+ TD GK+ A+ ALAK+A   NP IAFPG+R  EV+RPL+ LL  +  G++NFE+L  LTNLA ++D  R +I+KEK L ++E YMFE+HE +R+A+ ECMCNL+   EV++R+L + ND++KLLVLLC E E+  L +AA+G LA+L+ +  +   K++KV   W EI+Q +    +P IQHR +  + NM+ +   +  + +V S+M EI+  ++KL D   K N +  A   L   +++ LIKP 
Sbjct:    9 SVQLKEEGNKHFQAGEIDQAIDCYTKAIKTCKKEDKKALAVIYRNRSACFLKKENYSNAASDATKAIDVDAADIKALYRRCQAFEKLGKLDMAFKDVQRCATIEPKNKTFLETLRRLGAEIQQKLKTTFSTDSRVQNMFDILFSDEPDKEKREKAANNLIVLAREDAGAERIFQNNGVPLLMQLIDTGKP-EMILAAIRTLSGMCTGHRARATAIIHSVGISKLCSIMAVDNEEIALATANLFQCVNDSLSG-GDKR-----------------NYGKEEALVLDSS--KDLKDILLALLEMIASKNVSGHGRDQALNLLTKNVPRQNKKSTDNSKCLFTIDHGLKKILKVCG------QVPDLPDQLPM---TENTQLIASVLLSKLYDDLRCDPERDQFRDICDDYIKSKFDPNDMDKNIHAINTLSGILQGPFDLGNVLAGRQGVMEMMVALCGSEREVDQLVAVEALIHASTKTSKASFFISNGVSLLKEMYKKTKNEKIKIRALVGLCKLGSAGGDDYSMRQFAEGSTEKLAKQCRKWL---CNPTLDVRTRKWAIEGLAYLTNDADVKDDFAEDEPAMRAMFELTKSNDKTILYAVACTLVNCTNSYDKKEIIPEMVQLAKFSKQHVPEQHPKDKKDFIVRRVKRLLKAGVTSALAVMVKADNSILTDQ--TKEMLARVFLALTEDVKDRGIIVAQGGGKALIPLALEGTDKGKIKASHALAKIAAVSNPEIAFPGERIYEVVRPLVSLLGTDRDGMENFEALRGLTNLAGLNDKLRVKILKEKALPEIENYMFEDHEQIRQAATECMCNLVCCKEVQDRYLEDGNDKLKLLVLLCGEDEE-KLQRAAAGALAMLTAAQKKLAVKMTKVTEQWLEILQRLCIHDNPEIQHRGLVTVFNML-DADDQLAKKLVESDMLEILTYVAKLEDNPKKQNAIDAARACLSKAMDNGLIKPF 932

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BLAST of Protein unc-45 homolog A vs. UniProt/SwissProt
Match: sp|Q68F64|UN45B_XENLA (Protein unc-45 homolog B OS=Xenopus laevis OX=8355 GN=unc45b PE=2 SV=1)

HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0
Identity = 349/970 (35.98%), Postives = 544/970 (56.08%), Query Frame = 2

Query:   86 FEMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDE-KLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQT----LLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNL--LCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMK-NVVTCAEESLEALVNHKLIKPI 2953
             E     KE GN+YF+S D+  A+E Y   L  K ITD + K   Y+N+S CYLK   +    +   KA+ +   D K+L+RR  A   L K  +A  D ++   L+PKN+ + E +  +   I+ ++    S   +V  MF +L   +   + + K+ NNL VL RE + +  I+ +   N+L++  +   P  +I +A R LS +      +   I  L G     +++     E    A   L+NI+  L+                            + +  +EA+       L+     LL    SKK+S  GRD  L +L + +P  +  N   +KTL   + G  K+L+V          P   N + L   TP T++  ++L+  +YDDL  D +R+ FR +C +++      + ME  + A   +  + QGPF+ G+ +LG  G+++ ++ LT SE    Q +A++A++ A TK  +   II + + + ++IYK T ++ +KIRALVG+CKLGS GG D ++   AEGS  +LAK CRK+L    N + D    +WA EGLAYL+LDADVK+  V DE++L+ +  LC T + TI  LY +   L N TNSYD  E++PEM++LAK++KQH+PE H KD   F+  R+++L++ ++   L  + +  +S    Q  +KE I+R++L++    + RG I+  GGGKA+I LAL+ TD GK  A+  LAK+A   NP IAFPG+R  EV+RPL+ LL  E  G+QNFE+L+ALTNL+   D  R++I+KEK L ++E YMFE HE +R+A+ ECMCNL +  EVKERF  E NDR+KL+VLLC E E++ L +AA+G LAIL+ ++ +   K+++V + W EI+Q +    D  +QHR V +  N+I +  +E  + +V S M EI+  + K  D   K +++  A E+L   +++  IK +
Sbjct:    1 MEDPVQLKEEGNKYFQSNDYGNAIECYSKAL--KLITDKKMKAVLYRNRSACYLKQENYIQAAADASKAIDVDASDIKALFRRCQALEKLGKLDQAYKDVQRCATLEPKNRTFLEMLHRLGSNIQEKLHVQFSTDSRVQKMFEILLDENSDKEKREKAANNLIVLGREDAGAERIFQNNGVNLLMQLIETKDP-ELILSAVRTLSGMCTGHRARATAIVHLVGINKICSIMAVDHEEIALAACNLLQNIVDSLTG------------------------EDKKVHGKEEALVLDTKKDLKVITTHLLDMLVSKKVSGHGRDQALNLLNKNIPRYDLKNKDNSKTLFVVDVGLKKILKVLG------QVPELPNCLPL---TPNTRLNASVLINKLYDDLRCDPERDDFRKICEEYITGSFDPKDMEKNLHAIQTVSGILQGPFDLGNILLGMQGVMEMMVALTGSEKEVDQLVAVEALIHASTKLSRASFIITNGVSLLKDIYKKTKNEKIKIRALVGLCKLGSAGGTDYALRQFAEGSTDKLAKQCRKWL---CNTSLDIQTRKWAVEGLAYLTLDADVKDEFVEDEQSLKAMFELCKTSDKTI--LYSVATTLVNCTNSYDVKEVIPEMVQLAKFSKQHVPEQHPKDKKDFVLKRVKKLLQADVISALSCMVKADNSILTDQ--TKEQIARVFLALCDEPKDRGIIVAQGGGKAMIPLALEGTDVGKTKASHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLNTERDGVQNFEALLALTNLSGKSDKLRQKIVKEKALPEIENYMFENHEQIRQAATECMCNLAVNKEVKERFTAEGNDRLKLIVLLCGEDEEVKLQRAAAGTLAILTAAEKKLCHKMTEVTSQWLEILQRLCLNEDLQVQHRGVVITYNLI-SAEKELAKKLVESEMLEILTVIGKQADVPNKQHIINVAREALVKCLDYGFIKTV 926

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BLAST of Protein unc-45 homolog A vs. UniProt/SwissProt
Match: sp|Q99KD5|UN45A_MOUSE (Protein unc-45 homolog A OS=Mus musculus OX=10090 GN=Unc45a PE=1 SV=2)

HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0
Identity = 341/958 (35.59%), Postives = 535/958 (55.85%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFN-LLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQ--IKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGS-DAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS-DIRFIDKLSKV-NNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
              ++ GNE FK GD++ AL  Y   L+      D+ +  ++N++ C+LK+  +    S   KA++    D K+LYRRS A   L +  +A  D K+ + L+PKNK++QE +R +  QI+ +V   +S   KV  MF  LL   +   + K K+  NL VL RE + +      +   LL+        +++ AA R L  +      +T+    + G +   +++          A   L+ I   L +   K +R K            G++   P          A+ +   + +LL+      +S  GRD+ L +L++ VP K  +  N + TL   + G  K+LEVG          S  +    +  T  ++M+ +ILL+ ++DDL  D +RE F  LC +++ +      +  K+ A   +  L QGP +AG+  L  SG+++ ++ L  SE    Q +A++A++ A  K  +   I  + + + +++YK    D+++IRALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N   D    RWA EGLAYL+ DADVKE  V DE AL+ L  ++++     L+ + + L N TNSYD  E  P+M+ELAKYAKQH+PE H KD   F++ R+++L+   +   +  + +    SP   N+ +EL+SR++L++V   + RG ++  GGGKAL+ LAL+ TD G+  AAQALAK+ IT NP + FPG+R  EV+RPL+ LL +  +GLQNFE+LMALTNLA + +  R++I+KEK +  +E YMFEEHEM+RRA+ ECMCNL +  EV++ F  + NDR+KLLVL   E ++L L +AA+GGLA+L+S       ++ +V  +W EI+QA++   +  +QHR   ++ NM+   S+E    ++ S + EI+  L+K  +     V   A   LE  V ++LI+P
Sbjct:   23 QLRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAI-LHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTEETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVIFDALKEGVKKGFRGK-----------EGAIIVDP----------ARELKVLINSLLELLTEVGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGG---------SLQDAAGELTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRNWFEGHGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEREEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERSVLFAVGSALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMTCMVK--TESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDEL-LRRAAAGGLAMLTSMRPALCSRIPQVTTHWLEILQALLLSPNQELQHRGTVVVLNMM-QSSKEIAGTLMESEVLEILSVLAKGEESP---VTRAAAACLEKAVEYRLIQP 939

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BLAST of Protein unc-45 homolog A vs. TrEMBL
Match: A0A419PFM5 (Protein unc-45-like protein A OS=Clonorchis sinensis OX=79923 GN=UNC45A PE=4 SV=1)

HSP 1 Score: 727.628 bits (1877), Expect = 0.000e+0
Identity = 409/1031 (39.67%), Postives = 592/1031 (57.42%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRE---TSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGA-------------------AAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLEL-----------------------AKSCRKFLRDVSN--ANDD---------GSM-------------------------VRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLT-QLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLAL-DNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNL-------------LLLDE----VKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL----TDETM 2884
             KE  N  FK G F +A+ +Y   L      +  +   Y N++  +LK+  ++  + A   AL ++  DPK+L+RR+ A+  L K   A  DA+KLI L+ KN   Q  IR VE  +  ++  ++S   ++  MF+L++     ++   K++NNLT LI E   T+ SLIW +     L   C+      I+ A HR L+  F    ++ + + K   PQYFA+ I+S  PE      ++L  +L GL+Q+K Y+  KE       ++S  V    Y ++++D  V   V +  Q +++A NS +LSA  RD ILE+L+RF+PS++GI W++ ++  EG  ++ LEV                     A  R++   S       + T+P T+M VA LL+  ++DL SDK R  F +LC DF+LDL +D  +E+KVEAA++IG LF GP+E GS++L + G+L+GL LLT+     YQ +ALD I+LA  KK++CLS++  A+PI + +YK+ +D  +IRALV +CK G+ GG D++I SL EGS   L                       A+ CR  + +      NDD         GS                          VRWA EG AYLSL+A+VKE LV D + +R L  +      EC Y L  VLAN+TNS  +  + PE++ELAK+AKQHIPE H  DS+  +  R + L++  L V LY+LT Q+A    G Q   +ELISR+YLS   + ++RG ++QAG  KAL++L+L  NTD+GK  AAQALA++AIT +PR+ FPGQRSLE++RPL++LL I+   LQNFE L+ALTNLAS+DD HR RI+ E+G+ Q+++Y+F+EH MLRRA+ EC+ NL             L L+E     K  +L    +RVKLLVL C E EDL L++AA G LA +S D   I +++  + WFE +Q +       I HRA H+LRNM++ G R  CE+I  SNM E+IMALS+L    TDET+
Sbjct:   74 LKEKANSLFKDGLFREAIALYDQCLAESQPDNRLRCILYSNKAQAFLKLEDYENAVKASTDALNLNPFDPKALFRRAQAYEKLGKLQSALEDAQKLIRLESKNTAAQLLIRRVEHSVTQRIAESDSLPMRITTMFDLIQTESKNEEKLEKAINNLTALIGEVGTTAASLIWGNPHFAELFGLCE-HADQKIVRAVHRLLAHTFEHHMDRCMFVLKCLTPQYFADRIFSRNPEQALETCRFLSALLDGLTQLKAYQHAKEVAAENTNKESSKVAPTIYPKFKLDPKVEAPVQEIFQHMVRAVNSYRLSAPVRDYILEMLIRFIPSEKGIGWSRRIVELEGALDRFLEVAGEAGTSALTNWRSRRSRQLEAKRRADDPNSSAIEEIRLHTSPNTRMIVACLLSRFWEDLTSDKARTHFTELCSDFILDLFSDPFLETKVEAASVIGTLFLGPYEVGSSILSRPGVLEGLFLLTQCPNMLYQTVALDTIILATHKKEQCLSLVSKAVPILQNLYKSENDGTRIRALVALCKFGAAGGSDATIKSLTEGSAASLVLACRRLLLGIEQREPTIDEVAPARQCRAEISESGELLVNDDTDSESEEENGSTMKTRLRRSCLMTGDAPLSHLKESETVRWAIEGFAYLSLNAEVKEELVADADVIRTLFQIAALGLQECGYALANVLANLTNSLPRANVEPELVELAKFAKQHIPEQHPLDSNEHVNKRRQRLVEAGLPVALYNLTTQMASGPIGGQEGLRELISRLYLSTSEFVENRGKLVQAGAAKALLNLSLKSNTDSGKDIAAQALARLAITSDPRVTFPGQRSLELVRPLLRLLSIDCDALQNFEGLLALTNLASLDDLHRHRIMAERGVPQIDHYLFQEHPMLRRAATECVANLAQYHAFVVVCGGTLPLEEKDLGAKLPYLSSSTERVKLLVLYCCEFEDLLLVRAAIGALATMSYDPGIIKRITDTSAWFETIQTLAGHDAYCIAHRAAHLLRNMVIYGERSLCEYICQSNMLEVIMALSQLPDLGTDETL 1103

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BLAST of Protein unc-45 homolog A vs. TrEMBL
Match: A0A4S2JUW4 (TPR_REGION domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_011244 PE=4 SV=1)

HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0
Identity = 400/1024 (39.06%), Postives = 581/1024 (56.74%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRE---TSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGA-------------------AAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLEL-----------------------AKSCRKFLRDVSN--ANDD----------------------------------GSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLT-QLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLAL-DNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNL-------------LLLDE----VKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTD 2875
             KE  N  FK G F +A+ +Y   L      +  +   Y N++  +LK+  ++  + A   AL ++  D K+L+RR+ A+  L     A  DA+KLI L+PKN   Q  IR VE  +  ++  ++S   ++  MF+L++     ++   K++NNLT LI E   T+ SLIW +     L   C+      I+ A HR ++  F    ++ + + K   PQYFA+ I+S  PE      ++L  +L GL+Q+K Y   KE       +++  V    Y ++++D  V   V +  Q +++A NS +LSA  RD ILE+L+RF+PS++GI W++ ++  EG  ++ LEV                     A  R++   S       + T+P T+M VA LL+  ++DL SDK R  F +LC DF+LDL +D  +E+KVEAA++IG LF GP+E GS++L + G+L+GL LLT+     YQ +ALD I+LA  KK++CLS++  A+PI + +YK+ +D  +IRALV +CK G+ GG D++I SL EGS   L                       A+ CR  + +      NDD                                     VRWA EG AYLSL+A+VKE LV D + +R L  +      EC Y L  VLAN+TNS  +  + PE++ELAK+AKQHIPE H  DS+  +  R + L++  L V LY+LT QLA    G     +ELISR+YLS   + ++RG ++QAG  KAL++L+L  NTD GK  AAQALA++ IT +PR+ FPGQRSLE++RPL++LL I+   LQNFE L+ALTNLAS+DD HR RI+ E+G+ Q+++Y+F+EH MLRRA+ EC+ NL             L LD+     K  +L    +RVKLLVL C E EDL L++AA G LA +S D   I +++  + WFE +Q +       I HRA H+LRNM++ G R  CE+I  SNM E+IMALS+L D
Sbjct:    7 LKEKANSLFKDGLFREAIAIYDQCLAESQPDNRLRCILYSNKAQAFLKLEDYENAVKASTDALNLNPFDLKALFRRAQAYEKLGALQSALEDAQKLIRLEPKNTAAQLLIRRVEHSVTQRIAESDSLPMRITTMFDLIQTESQNEEKLEKAINNLTALIGEVGATAASLIWSNPHFAELFGLCE-HADQKIVRAVHRLIAHTFEHHMDRCMFVLKCLTPQYFADRIFSRHPEQALETCRFLSALLDGLTQVKAYHHAKEVSAENANKENSKVAPTMYPKFKLDPKVEAPVQEIFQHMVRAVNSYRLSAPVRDYILEMLIRFIPSEKGIGWSRRIVELEGALDRFLEVAGEAGTSALANWRSRRSRQLEAKRRADDPSSSAIEEVRLHTSPNTRMIVACLLSRFWEDLTSDKARTHFTELCSDFILDLFSDPFLETKVEAASVIGTLFLGPYEVGSSILSRPGVLEGLFLLTQCPNMLYQTVALDTIILATHKKEQCLSLVSKAVPILQSLYKSENDGTRIRALVALCKFGAAGGSDATIKSLTEGSTASLVLACRRLLLGIEQREPTIDEVAPARQCRAEISESGELLVNDDTDSESEEESGSTMKTRLRRSCLMAGDAPLSHLKESETVRWAIEGFAYLSLNAEVKEELVADADVIRTLFQIAALGLQECGYALANVLANLTNSLPRANVEPELVELAKFAKQHIPEQHPLDSNEHVSKRRQRLVEAGLPVALYNLTTQLASGPIGGHEGLRELISRLYLSTSEFVENRGKLVQAGAAKALLNLSLKSNTDGGKDIAAQALARLTITSDPRVTFPGQRSLELVRPLLRLLSIDCDALQNFEGLLALTNLASLDDLHRHRIMAERGVPQIDHYLFQEHPMLRRAATECVANLAQYHAFVVLCGGTLPLDDKDLGAKLPYLSSSTERVKLLVLYCCEFEDLLLVRAAVGALATMSYDPGIIKRITDTSAWFETIQTLAGHDACCIAHRAAHLLRNMVIYGERSLCEYICQSNMLEVIMALSQLPD 1029

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BLAST of Protein unc-45 homolog A vs. TrEMBL
Match: A0A1S8X2Z1 (Tetratricopeptide repeat protein OS=Opisthorchis viverrini OX=6198 GN=X801_03044 PE=4 SV=1)

HSP 1 Score: 709.138 bits (1829), Expect = 0.000e+0
Identity = 404/1031 (39.19%), Postives = 585/1031 (56.74%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRE---TSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGA-------------------AAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSN-------------------------ANDD---------GS-------------------------MVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSP-GSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLAL-DNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNL-------------LLLDE----VKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL----TDETM 2884
             KE  N  FK G F +A+ +Y   L      +  +   + N++  +LK+  ++  + A   AL ++ +DPK+L+RR+ A+  L     A  DA+KLI L+PKN   Q  IR VE  +  ++  ++S   K+ +MF+L++     ++   K++NNLT LI E   T+ SLIW +     L   C+      I+ A HR ++  F    ++ + + K   PQYFA+ I+S  PE      ++L  +L GL+Q+K Y+  +E       ++S  V    Y ++++D  V + V +  Q +++A NS +LSA  RD ILE+L+RF+PS++GI W++ ++  EG  ++ LEV                     A  R++   S       + T+P T+M VA LL+  ++DL SDK R  F +LC DF+LDL +D  +E+KVEAA++IG LF GP+E GS++L + G+L+GL LLT+     YQ +ALD I+LA  KK++CLS++  A+PI + +YK+ +D  +IRALV +CK G+ GG D++I SL EGS   L  +CR+ L  +                            NDD         GS                          VRWA EGLAYLSL+A+VKE LV D + +R L  V      EC Y L  VLAN+TNS  +  + PE++ELAK+AKQHIPE H  DS+  +  R + L++  L V LY+LT    S P G     +ELISR+YLS     ++RG ++QAG  KAL++L+L  NTD GK  AAQALA++AIT +PR+ FPGQRSLE++RPL++LL I+   LQNFE L+ALTNLAS+DD HR RI+ E+G+ Q+++ +F+EH MLRRA+ EC+ NL             L L+E     K  +L    +RVKLLVL C E EDL L++AA G LA +S D   I +         I   +       I HRA H+LRNM+++G R  CE+I  SNM E+IMALS+L    TDET+
Sbjct:    7 LKEKANSLFKDGLFREAIALYDQCLAESQSDNRLRCILHSNKAQAFLKIEDYENAVKAATDALNLNPLDPKALFRRAQAYEKLGALQSALEDAQKLIRLEPKNTAAQLLIRRVEHSVTQRIAESDSLPMKITSMFDLIQTESKNEEKLEKAINNLTALIGEVGATAASLIWGNPHFAELFDLCK-HADQKIVRAVHRLMAHTFEHHMDRCMFVLKCLTPQYFADRIFSRNPEQALETCRFLSALLDGLTQLKAYQHAREVAAENTNKESSKVAPTIYPKFKLDPKVEEPVQEIFQHMVRAVNSYRLSAPVRDYILEMLIRFIPSEKGIGWSRKIVELEGALDRFLEVAGEAGTSALTNWRSRRSRQLEAKRRADDPISSAIEEVRLHTSPNTRMIVACLLSRFWEDLTSDKARTHFTELCSDFILDLFSDPFLETKVEAASVIGTLFLGPYEVGSSILSRPGVLEGLFLLTQCPNMLYQTVALDTIILATHKKEQCLSLVSKAVPILQNLYKSENDGTRIRALVALCKFGAAGGSDATIKSLTEGSTASLVLACRRLLLGIEQREPTIDEVAPARQCRAEVSESGELLVNDDTDSESEEEGGSTMKTRLRRSCLMTGGAPLSHLKESETVRWAIEGLAYLSLNAEVKEELVADADIIRTLFQVAALGLQECGYALANVLANLTNSLPRANVEPELVELAKFAKQHIPEQHPLDSNEHVSKRRQRLVEAGLPVALYNLTTRLASGPIGGHEGLRELISRLYLSTSELVENRGKLVQAGAAKALLNLSLKSNTDGGKDIAAQALARLAITSDPRVTFPGQRSLELVRPLLRLLSIDCDALQNFEGLLALTNLASLDDLHRHRIMAERGVPQIDHCLFQEHPMLRRAATECVANLAQYHAFVVVCGGTLPLEEKDLGAKLPYLSSSTERVKLLVLYCCEFEDLFLVRAAVGALATMSYDPGIIKR---------ITDTLAGHDAYCIAHRAAHLLRNMVIHGERSLCEYICQSNMLEVIMALSQLPDLGTDETL 1027

[Close]

BLAST of Protein unc-45 homolog A vs. TrEMBL
Match: A0A5K3FTK2 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 694.115 bits (1790), Expect = 0.000e+0
Identity = 403/989 (40.75%), Postives = 587/989 (59.35%), Query Frame = 2

Query:   92 MTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRE---TSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXX-XSGSVNFRP---YQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGAAAH---------RSESTPS----------QTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSM-----------------VRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSL-TQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALD-NTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNL-------------LLLDEVKE-----RFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNM-IVNGSREFCEFIVNSNMFEIIMALSK 2866
            M    K   N  F  G+  +A+E+Y   L+  +I  + +    +N + C+L +  +D  I    +AL +   D K+LYRR +A+       +A +D ++L+ LDPKNK  ++    +E  + ++ E   S  GK+N+MF++L     +D+   K+LNNL  L  E    +++ IW H   + + + C    P +++      L  +   + +  L +     PQYF   ++S   +      ++L  +L  L+QI  YR+ +E      ++ KS   +F P   Y  Y++DE V + V + L  +++A +S +L A+ RD++LE+L   VP   GI W++  +  EG   +LLEV AAA          R   T S          + +   ++ T+  T+MTVA LL+ I+DDL SDKDR+KF   C DF+LDLLTD+ +ESKVEAA +IG LF GP+E GS VL + GIL+GLLLLT++E  +YQ +ALD I+LA  KKDKC++II  A+PI   +YK+  DA+K+RALVG+CKLG +GG D+S PS+AEGS + L K+CR+ L    + ++                      RWA +GLA+LSL  +VKEA+V D + L  +  V +    +  +PL ++LAN+TNS+++ EI PEM+ELAK+ KQHIPE HE D  + I  R + ++   L   L++L T+L  ++  SQ   +EL+SRIYLS       RG ++ AG G+ LI+LAL+ NTD GK  AAQALAK+ IT +PR+ FPGQRSLEVIRP++QLL I+   LQNFE+L+ALTNLAS+DD HR RII E GL  VE+YMFEEH+ LRRA+VEC  NL             L L+E  E       L   ++ VKLL+L C E  D+AL++AA+G LA +S D   I K+  VN WF+I+QA+ A    AIQHRA  +LRN+ +V G R   E++  S+M E++MAL++
Sbjct:    3 MVDELKTKANALFSKGNVKEAIEIYEKCLSHPEIDKNLEEIVKRNLAQCFLNLGNYDQAIEVATEALALLPSDTKALYRRCIAYEKSGNLRDAISDVRRLVQLDPKNKAIKDLAFRLESSVMAKKEEAESLTGKINSMFSILTDPTASDERMEKALNNLIALNNEEKAAASAKIWSHPGMSQIFELCNHPKP-DLVNLVLTLLGSIIKQNSDYGLRLLNTLSPQYFIRRVFSPCNDASAGMCKFLRCLLESLTQISVYRKAREAAIEADQKDKSKPKSFLPRNIYPPYKLDEKVKKPVEEVLCHIIRATSSYRLEASARDTLLELLAWIVPEATGIAWSRQFVAGEGNIERLLEVAAAASASMITQRPVRGGRTASAEAPEAPGLPEISRGGVLKTSANTRMTVACLLSRIFDDLHSDKDRQKFSQQCADFILDLLTDKFIESKVEAAAVIGTLFSGPYEVGSHVLSREGILEGLLLLTQAENVAYQTVALDTIILATNKKDKCMAIIDQAVPILRSLYKSSDDAIKVRALVGLCKLGVLGGTDASSPSMAEGSTVILTKACRRLLLGQQSGDNKAEAETSVDFARIGPLSAANSTRWAVDGLAFLSLAGEVKEAIVKDRDLLTAIYKVAEMGYFDAAFPLASLLANLTNSFEEKEITPEMVELAKFTKQHIPEKHEADDPKVIAQRRQTMIDAGLPSCLFNLTTKLLTNTVASQPGIRELVSRIYLSCAECVDCRGVLVSAGAGRVLINLALENNTDGGKRAAAQALAKLTITADPRLTFPGQRSLEVIRPILQLLNIDCPALQNFEALLALTNLASLDDNHRSRIIAEGGLPLVEHYMFEEHKQLRRAAVECFANLAQHHATVIACGGTLPLEEHVEVGRKLPSLASGSEVVKLLMLYCLEEADVALVRAAAGALATMSYDPGIIKKIVAVNKWFDILQAVAAHPSSAIQHRAAFLLRNLVVVPGERGLAEYLAQSSMLEVLMALAQ 990

[Close]

BLAST of Protein unc-45 homolog A vs. TrEMBL
Match: K1PAR4 (Unc-45-like protein A OS=Crassostrea gigas OX=29159 GN=CGI_10012024 PE=4 SV=1)

HSP 1 Score: 687.952 bits (1774), Expect = 0.000e+0
Identity = 377/952 (39.60%), Postives = 581/952 (61.03%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQM--DLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLAL-DNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
             KE GN  FK G   +AL++Y   L   DI + +K    KN++ C+LK   +  VI  C  AL+I+  DPK+LYRR  A+ +L K  +A  DA  +I +DPKN   Q  ++ +   I+ +V+  NS   KV  MF+L+       + +L++ NNL VL RE + +   C    + L K  Q+  +  ++I +AA R LS L   S E++  +    G Q     +       C      ++N+++ +S + +YR+K + Y+ E K+     N   Y +++++E   +++++  ++L++   S K+S  GRDS +E++++ +   +G+ WTK  L T+G    LL + +A  + E+          I+ T  +K   ++ LA IYDDL SDK+R+ FR+ C  F  +L  D + ESKVEA   I  L QGP+E G+ +LG  G+ Q +L L  S+   +Q++A++AIV + +KKDKC  ++ DA+P+ +++Y+   D +K+RALVG+CKLGS GG D+S   + +GS L LAK+CRKFL D + + D   + RW +EGLAYL+LDA+VKE L+ND  ALR+L+ V        LYP  +V  N+TNSY+KP+I+PEM+ELAKY+KQH+PE HEKD    +K R+ +L K  +   L ++      SP     ++E +SRI+ ++   E  RG ++Q GG K L+ L+  +NTD GK+ A+ +LA++ IT NP   FPGQR  EV+RPLI LL ++ T LQNFE+L+ALTNLAS++D  R++I+ EKGL+ +E+YM E+HEMLRRA  ECMCN+++ ++V + F   ENDR+KL+VL C + ED  +++AA+G LA+L+   +   K+ +V  W EI+ + V   +  IQHR  ++LRNM+ +  +E  E ++   M E++MALS L D   + V  CA   LE  V ++LIKP
Sbjct:   13 LKEEGNTLFKEGKIAEALDVYTKALGIVDIKNGDKAVILKNRAACHLKEEDYHAVIDDCSAALEITPNDPKALYRRCQAYEHLGKVEDAYKDAAAIIKVDPKNTAVQPILQRLNPIIQEKVKQQNSTSAKVAQMFDLVFDPKTDKEQRLQACNNLIVLAREEAGAKSICEGSPSGLDKLLQLLQEKDVDINQAAIRTLSCLTADSQERSYLVLDKMGLQKMVTFMSVKHDGLCTSTALLIQNLITAISAVPEYRKKVQHYQDERKKG----NPCRYPQFELNEKQTEFIDNVFKSLVKMLQSSKVSGNGRDSAMELIIKNMLRSDGVQWTKKFLDTDG-IEGLLTIASAIPQHETCN--------IEITENSKYHASVALAKIYDDLASDKERDIFREQCSAFFKELFGDSLFESKVEAIKCISSLLQGPYEVGNIILGFDGVTQIMLALANSDNPLHQQLAVEAIVHSASKKDKCAGLLNDAVPVLKKLYQESIDTVKVRALVGLCKLGSFGGSDASHRPMQDGSTLALAKACRKFLNDPNKSVD---LRRWGTEGLAYLTLDAEVKEELINDTSALRSLIDVVAKADKNILYPAASVFVNLTNSYEKPDIMPEMIELAKYSKQHVPEEHEKDKPEPVKQRVHKLAKAGVVTALVAIA--TTDSPN----TREQVSRIFSAITAEEDLRGIVVQQGGAKTLVDLSTKNNTDAGKILASWSLARITITANPETTFPGQRIYEVVRPLISLLHVDRTALQNFEALLALTNLASLNDSLRKKIVAEKGLASIEHYMTEDHEMLRRAGTECMCNMVMNEQVAKTFEA-ENDRLKLIVLYCGD-EDELVVRAATGALAMLTHSEKICRKVLEVKPWQEILLSTVVSENVEIQHRGCYVLRNML-SVDKEMAEKVIEGQMLEVLMALSILEDPQKEVVKKCAASCLEICVKYELIKP 939

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Cavefish
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:103041047])

HSP 1 Score: 563.918 bits (1452), Expect = 0.000e+0
Identity = 349/966 (36.13%), Postives = 539/966 (55.80%), Query Frame = 2

Query:   98 THFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPE----HCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAV----AQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDI-----RFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
            +  +E GN  FKSGD   AL  Y   L   D  D E    ++N+S CYLK+ ++    +   KAL   + D K+ +RR+ A   L +  +A  DA+K   L+PKNK +QE +R++  QI+ +    +S   +V  MF LL  +   +  +LK+  NL VL RE + +      D   LL+        +I+ +A R L  L      +T+ I    G      ++ S         C L     E +  G+   KD+R K                         DEA+    ++ +   L+ L+    +  +S  GRDS + +LV+ VP K   N   + TL   + G  K+LEV      S + P  T+  +L D TP   M  A+LL  +YDDL SDK+RE F  LC ++V        +E+K+ A   + +L QGP + G+  L  SGI++ ++ L  SE  ++Q++A++ ++ A  K  +   I  + + + +++YK + ++ +++RALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N +   +  RWA EGLAYL+ DADVKE LV D+ AL+ +  + K+     L+ + + L N TNSY+  +  P+++ELAKYAKQH+PE H KD+  F++ R+ +L++  +   L  + +    SP      +E I+R++L++V  ++ RG ++  GGGKAL+ L  D+TD GK+ AAQALAK+ IT NP IAFPG+R  EV+RPL+ LL +E + LQNFE+LMALTNLA + D  R++IIKEK + ++E YMFEEH+++R A+ ECMCNL+L  EV++ +L  ++DR+KLLVL C E +D  L KAA+G LA+L+ ++     R  D  S   +W EI+QA++      ++HR V +  NM+    R   E ++ S   EI+  L+K  D    +V+  ++  L+  + + LI+
Sbjct:    6 SALREEGNNLFKSGDVQGALSCYTKALKLSD-NDSENAVLFRNRSACYLKLEEYSKAEADATKALDTDQGDIKARFRRAQALHKLGRLDQAFLDAQKCAQLEPKNKAFQELLRQLSVQIQQKAVQLSSTDSRVQQMFKLLLDTSAQESDRLKAAQNLVVLSREDAGAEQIFRNDGVKLLQNLLDSRQEDIVLSALRTLVGLCTGHQSRTMAIVNELGMDRLCGVMGSGASAVSLAACHLLQVMFEALTEGMK--KDFRGK-------------------------DEAILPEPSRELRSMLRHLIDMLPASSVSGPGRDSAINLLVKQVPRKSQKNPDNSLTLWVIDNGIKKILEV------SGTVPEITDGPTLTDNTP---MNCAVLLNKLYDDLKSDKERENFNKLCEEYVQHHFEGSGLENKLRAIQTVSVLLQGPSDVGNRTLEMSGIMEAVISLCASENITHQQVAVETLIHAAGKAKRASFITANGVALLKDLYKKSENEQIRVRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDSLPQTSRRWAIEGLAYLTFDADVKEDLVGDKNALQAMFQLAKSEDKTVLFAIGSTLVNCTNSYEVEKPDPQLVELAKYAKQHVPEEHPKDAKSFVEKRLVKLLEAGVVSALVCMVK--QESPALTETCRECIARVFLALVERQEDRGTVVAQGGGKALLPLVSDSTDVGKIKAAQALAKITITSNPEIAFPGERVYEVVRPLVSLLALECSLLQNFEALMALTNLAGISDRLRQKIIKEKAVPKIEGYMFEEHDLVRAAATECMCNLVLSPEVQKLYLATDSDRLKLLVLYCGE-DDERLRKAAAGTLAVLTGEMPEVCARIPDVTS---HWLEILQALLLSESQDLRHRGVVITLNMM-QADRSLAEKLMESEALEILSVLAKTADANQASVIKASQHCLDLAMEYGLIR 924

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Cavefish
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:103041047])

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 349/964 (36.20%), Postives = 538/964 (55.81%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPE----HCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAV----AQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDI-----RFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
             +E GN  FKSGD   AL  Y   L   D  D E    ++N+S CYLK+ ++    +   KAL   + D K+ +RR+ A   L +  +A  DA+K   L+PKNK +QE +R++  QI+ +    +S   +V  MF LL  +   +  +LK+  NL VL RE + +      D   LL+        +I+ +A R L  L      +T+ I    G      ++ S         C L     E +  G+   KD+R K                         DEA+    ++ +   L+ L+    +  +S  GRDS + +LV+ VP K   N   + TL   + G  K+LEV      S + P  T+  +L D TP   M  A+LL  +YDDL SDK+RE F  LC ++V        +E+K+ A   + +L QGP + G+  L  SGI++ ++ L  SE  ++Q++A++ ++ A  K  +   I  + + + +++YK + ++ +++RALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N +   +  RWA EGLAYL+ DADVKE LV D+ AL+ +  + K+     L+ + + L N TNSY+  +  P+++ELAKYAKQH+PE H KD+  F++ R+ +L++  +   L  + +    SP      +E I+R++L++V  ++ RG ++  GGGKAL+ L  D+TD GK+ AAQALAK+ IT NP IAFPG+R  EV+RPL+ LL +E + LQNFE+LMALTNLA + D  R++IIKEK + ++E YMFEEH+++R A+ ECMCNL+L  EV++ +L  ++DR+KLLVL C E +D  L KAA+G LA+L+ ++     R  D  S   +W EI+QA++      ++HR V +  NM+    R   E ++ S   EI+  L+K  D    +V+  ++  L+  + + LI+
Sbjct:  117 LREEGNNLFKSGDVQGALSCYTKALKLSD-NDSENAVLFRNRSACYLKLEEYSKAEADATKALDTDQGDIKARFRRAQALHKLGRLDQAFLDAQKCAQLEPKNKAFQELLRQLSVQIQQKAVQLSSTDSRVQQMFKLLLDTSAQESDRLKAAQNLVVLSREDAGAEQIFRNDGVKLLQNLLDSRQEDIVLSALRTLVGLCTGHQSRTMAIVNELGMDRLCGVMGSGASAVSLAACHLLQVMFEALTEGMK--KDFRGK-------------------------DEAILPEPSRELRSMLRHLIDMLPASSVSGPGRDSAINLLVKQVPRKSQKNPDNSLTLWVIDNGIKKILEV------SGTVPEITDGPTLTDNTP---MNCAVLLNKLYDDLKSDKERENFNKLCEEYVQHHFEGSGLENKLRAIQTVSVLLQGPSDVGNRTLEMSGIMEAVISLCASENITHQQVAVETLIHAAGKAKRASFITANGVALLKDLYKKSENEQIRVRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDSLPQTSRRWAIEGLAYLTFDADVKEDLVGDKNALQAMFQLAKSEDKTVLFAIGSTLVNCTNSYEVEKPDPQLVELAKYAKQHVPEEHPKDAKSFVEKRLVKLLEAGVVSALVCMVK--QESPALTETCRECIARVFLALVERQEDRGTVVAQGGGKALLPLVSDSTDVGKIKAAQALAKITITSNPEIAFPGERVYEVVRPLVSLLALECSLLQNFEALMALTNLAGISDRLRQKIIKEKAVPKIEGYMFEEHDLVRAAATECMCNLVLSPEVQKLYLATDSDRLKLLVLYCGE-DDERLRKAAAGTLAVLTGEMPEVCARIPDVTS---HWLEILQALLLSESQDLRHRGVVITLNMM-QADRSLAEKLMESEALEILSVLAKTADANQASVIKASQHCLDLAMEYGLIR 1033

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Cavefish
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:103041047])

HSP 1 Score: 540.421 bits (1391), Expect = 5.537e-177
Identity = 342/966 (35.40%), Postives = 526/966 (54.45%), Query Frame = 2

Query:   98 THFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPE----HCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAV----AQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDI-----RFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
            +  +E GN  FKSGD   AL  Y   L   D  D E    ++N+S CYLK+ ++    +   KAL   + D K+ +RR+ A   L +  +A  DA+K   L+PKNK +QE +R++  QI+                               K+  NL VL RE + +      D   LL+        +I+ +A R L  L      +T+ I    G      ++ S         C L     E +  G+   KD+R K                         DEA+    ++ +   L+ L+    +  +S  GRDS + +LV+ VP K   N   + TL   + G  K+LEV      S + P  T+  +L D TP   M  A+LL  +YDDL SDK+RE F  LC ++V        +E+K+ A   + +L QGP + G+  L  SGI++ ++ L  SE  ++Q++A++ ++ A  K  +   I  + + + +++YK + ++ +++RALVG+CKLGS GG D S+   AEGS L+LAK CRK+L    N +   +  RWA EGLAYL+ DADVKE LV D+ AL+ +  + K+     L+ + + L N TNSY+  +  P+++ELAKYAKQH+PE H KD+  F++ R+ +L++  +   L  + +    SP      +E I+R++L++V  ++ RG ++  GGGKAL+ L  D+TD GK+ AAQALAK+ IT NP IAFPG+R  EV+RPL+ LL +E + LQNFE+LMALTNLA + D  R++IIKEK + ++E YMFEEH+++R A+ ECMCNL+L  EV++ +L  ++DR+KLLVL C E +D  L KAA+G LA+L+ ++     R  D  S   +W EI+QA++      ++HR V +  NM+    R   E ++ S   EI+  L+K  D    +V+  ++  L+  + + LI+
Sbjct:    6 SALREEGNNLFKSGDVQGALSCYTKALKLSD-NDSENAVLFRNRSACYLKLEEYSKAEADATKALDTDQGDIKARFRRAQALHKLGRLDQAFLDAQKCAQLEPKNKAFQELLRQLSVQIQQ------------------------------KAAQNLVVLSREDAGAEQIFRNDGVKLLQNLLDSRQEDIVLSALRTLVGLCTGHQSRTMAIVNELGMDRLCGVMGSGASAVSLAACHLLQVMFEALTEGMK--KDFRGK-------------------------DEAILPEPSRELRSMLRHLIDMLPASSVSGPGRDSAINLLVKQVPRKSQKNPDNSLTLWVIDNGIKKILEV------SGTVPEITDGPTLTDNTP---MNCAVLLNKLYDDLKSDKERENFNKLCEEYVQHHFEGSGLENKLRAIQTVSVLLQGPSDVGNRTLEMSGIMEAVISLCASENITHQQVAVETLIHAAGKAKRASFITANGVALLKDLYKKSENEQIRVRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWL---CNDSLPQTSRRWAIEGLAYLTFDADVKEDLVGDKNALQAMFQLAKSEDKTVLFAIGSTLVNCTNSYEVEKPDPQLVELAKYAKQHVPEEHPKDAKSFVEKRLVKLLEAGVVSALVCMVK--QESPALTETCRECIARVFLALVERQEDRGTVVAQGGGKALLPLVSDSTDVGKIKAAQALAKITITSNPEIAFPGERVYEVVRPLVSLLALECSLLQNFEALMALTNLAGISDRLRQKIIKEKAVPKIEGYMFEEHDLVRAAATECMCNLVLSPEVQKLYLATDSDRLKLLVLYCGE-DDERLRKAAAGTLAVLTGEMPEVCARIPDVTS---HWLEILQALLLSESQDLRHRGVVITLNMM-QADRSLAEKLMESEALEILSVLAKTADANQASVIKASQHCLDLAMEYGLIR 894

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Cavefish
Match: unc45b (unc-45 myosin chaperone B [Source:NCBI gene;Acc:266640])

HSP 1 Score: 432.95 bits (1112), Expect = 7.359e-136
Identity = 237/587 (40.37%), Postives = 369/587 (62.86%), Query Frame = 2

Query: 1202 TPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILS-SDIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMK-NVVTCAEESLEALVNHKLIKP 2950
            T  T++  ++LL  +YDDL  D +R+ +RD+C +++        M+  + A N +  L QGPF+ G+A++G+ G+++ ++ L  SE    Q +A++AI+ A TK  +   II + + + ++IYK T ++ +KIRALVG+CKLGS GG D S+   AEGS  +LAK CRK+L    N   D    +WA EGLAYL+ DADVK+  V DE A+R +  + K    +           +     K EI+PEM++LAK++KQH+PE H KD   FI +R+++L+K  ++  L  + + ADSS  + + +KE+++R++L++    + RG I+  GGGKALI LA++ TD GK+ A  ALA++A   NP IAFPG+R  EV+RPL+ LL  E  G QNF++L +LTNLA+  D  R +I+KEK L ++E YMFEEHE +R+A+ ECMCNL+   EV+ER++ + ND++KLLVLLC+E ED  L  AA+G LA+L+ +  +   K++KV   W EI+Q +    +P +QHR + ++ NM+     E  + ++ S + EI+  ++K  D   + + +  A   +   ++  LIKP
Sbjct:  345 TENTQLIASVLLNKLYDDLRCDPERDNYRDVCDEYIKGKFDPNDMDKNIHAINALSGLLQGPFDVGNALVGRQGVMEMMVALCSSEREVDQLVAIEAIIHASTKMSRASFIISNGVSLLKDIYKKTKNEKIKIRALVGLCKLGSAGGDDYSMRQFAEGSTEKLAKQCRKWL---CNPTLDVRTRKWAIEGLAYLTSDADVKDDFVEDEPAMRAMFELAKVRQAK----------TIRGQILKKEIIPEMVQLAKFSKQHVPEQHPKDKKDFIDSRVKKLLKAGVTSALAVMVK-ADSSILT-DQTKEMLARVFLALSEDPKDRGTIVAHGGGKALIPLAVEGTDAGKIKACHALARIAAISNPDIAFPGERVYEVVRPLVSLLNTERDGTQNFDALRSLTNLAAKSDKLRLKIMKEKALPEIENYMFEEHEQIRQAATECMCNLVCCKEVQERYMEDGNDKLKLLVLLCSE-EDDKLQIAAAGALAMLTAAQKKLCVKMTKVTVQWLEILQRLCLHDNPQVQHRGMVIIFNML-EADEELAKKLIESELLEILSYVAKQEDNPKRQDAIDAARACVSRAMDLGLIKP 914

HSP 2 Score: 89.3521 bits (220), Expect = 1.064e-17
Identity = 54/169 (31.95%), Postives = 92/169 (54.44%), Query Frame = 2

Query:   98 THFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLN--YYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS 598
               K+ GN++F++G+ DKA+E Y   L    +  D+K+    ++N+S C+LK   +    S   KA+ +   D K+LYRR  A   L K   A  D ++   L+PKNK + E +R +  +I+ +++ + S   +V  MF++L   +   + K K+ NNL VL RE + +
Sbjct:   16 VQLKDEGNKHFQAGEIDKAIESYTKALK---VCKDKKVQAVIFRNRSACFLKKENYTSAASDASKAIDVDAADIKALYRRCQALEKLGKLDMAFKDVQRCAALEPKNKTFLETLRRLGAEIQQKLKTSFSTDSRVQNMFDILFSEEEDKEKKEKAANNLIVLAREDAGA 181

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Cavefish
Match: spag1a (sperm associated antigen 1a [Source:NCBI gene;Acc:564953])

HSP 1 Score: 68.1662 bits (165), Expect = 1.850e-11
Identity = 40/142 (28.17%), Postives = 73/142 (51.41%), Query Frame = 2

Query:   98 THFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQ 523
            T  K+ GN+  K G F+ A+E Y   L  K      + + Y N+++CYL++ ++      CD AL++   + K+ YRR+LA   L  +  A  D ++++ LDP  +  ++ ++EV   +R  +         ++   +LLKQ
Sbjct:  269 TLLKQEGNDMVKKGQFESAIEKYSECLKIKS----SECSIYTNRAICYLRLDQYAEAKQDCDTALQMEPTNKKAFYRRALAHKGLKDYLSASTDLQEVLQLDPNVREAEQELQEVTVLLRESLLTAQGKNTHIHTYTSLLKQ 406

HSP 2 Score: 53.9138 bits (128), Expect = 5.588e-7
Identity = 38/126 (30.16%), Postives = 59/126 (46.83%), Query Frame = 2

Query:   98 THFKELGNEYFKSGDFDKALEMY---INGLNTKDITDDEKLNY-YKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQ 463
               K  GN  FK+G F  AL  Y   I G  T  I   E +   Y N++ CYLK       I  C +AL++     K L RR++A+ +L ++ +A  D K ++ +D   +   + I  + K +  Q
Sbjct:   92 ARLKNEGNLLFKNGQFGDALGKYTQAIEGCETAGIDSPEDVCILYSNRAACYLKDGNCTDCIQDCTRALELCPFSLKPLLRRAMAYESLERYRKAYVDYKTVLQIDVSVQAAHDSIHRITKMLIEQ 217

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Sea Lamprey
Match: unc45b (unc-45 myosin chaperone B [Source:NCBI gene;Acc:266640])

HSP 1 Score: 497.278 bits (1279), Expect = 8.036e-161
Identity = 335/965 (34.72%), Postives = 512/965 (53.06%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQ-VENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQ----TLLQACNSKKLSATGRDSILEILVRFVPSK--EGINWTKTLLYTE-GGFNKLLEV-GAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELI--SRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIR-FIDKLSKVNN-WFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKPI 2953
              +E GN +FK+GDF  A+  Y   +     T  +    Y+N++ CYLK  K+    +   KA+ +++ D K+L+RR  A   L K   A  D ++   + P N+++ E ++++  +I+ + +    S   +V  MF +L  S +  D K  + +NL VL RE + +      +   LL+       + ++ AA R LS           E+ K H  +  A M    + + C L  Q  E I      I          +T     +G       +R   +EA+ + V+  L+     LL     KK+S  GRD+ L +L++ VP K     + +KT+  T   G  ++L V GA     +S P           T +T+++ ++LL  +YDDL +D +RE +  LC +FV    + E M   + A   I  L  GP++ G+ VLG+ G+L+ ++ L  SE    Q +A +A+VLA  K  +   I  + I + ++IYK   +D +KIRALVG+CKLGS GG D S+   AEGS  +LAK CRK+L        D    RWA EGLAYL+LDADVK+  V DE AL+ +  + +      +Y + + L N TNSYD  E +PE+++LAKY KQHIPE H K     +  R++  ++ ++       T+       SQN+    +   R++L++      RG II  GGGK LI LAL+ T  GK+ AA ALAK+ I  NPRI F G+   EV+RPL+ LL  E  GL NFE LMALTNLA  ++  R++IIKEK + ++E YMFEEHE +R A+ +CMCN+++  EV+E FL E NDR+K+ VLLC E E+   I AASG LA+L+S  +    ++  V   W EI+Q ++   +  +QHR + +  N+++   R+  + ++   + EI++ LSK        +   A   L A +++ LIKP 
Sbjct:    8 QLREEGNGFFKAGDFSSAISCYSKAIKVCQ-TPSDLATLYRNRAACYLKTEKYAEAATDSTKAIDVNQSDIKALFRRCQALEKLGKLDHAYKDVQRCATIQPNNRMFLETLQQLRARIQEKKLHEQFSTDRRVEQMFEILFDSSIEKDKKETAAHNLIVLAREEAGAERIFRSNGVALLQRLMESKDVEMLLAAMRTLS-----------ELCKEHRARATAIMYQVGLDKLCGLMAQNHEEISLASCNI---------LQTIYTSLTGKDKSEHIKR---EEAIVKDVSKDLRRMLLKLLDMLIDKKVSIHGRDNCLNLLIKNVPCKTLHDRDNSKTIFLTSYAGLPQILTVAGAIPELPDSLP----------VTDETRLSASVLLHKLYDDLRNDTEREVYDKLCDNFVTGSFSGEDMTKNLHAIQTISGLLAGPYDVGNRVLGQKGVLETIISLAGSESELEQLVATEALVLASAKTSRATFITTNGITLLKDIYKRARNDKIKIRALVGLCKLGSAGGTDYSMRQFAEGSTEKLAKQCRKWL---CCPTIDNRTKRWAVEGLAYLTLDADVKDDFVEDEAALKAMFDLARAGDKTIIYSVSSALVNCTNSYDTKERVPELVQLAKYTKQHIPEDHPKSKKNIVIYRLQGHLQHSVYHQTRCPTRAHKIINLSQNSPLWYVCAHRVFLALAEDPNDRGIIISHGGGKGLIPLALEGTKEGKIKAAHALAKLTINANPRIVFHGETIYEVVRPLVSLLNSELDGLPNFEGLMALTNLAGDNEKLRQKIIKEKAMPEIENYMFEEHEQIRLAATQCMCNMVISKEVQEMFLKEGNDRLKMAVLLCGEDEEPLQI-AASGMLAMLTSAHKSLCSRVPTVTTQWLEILQRLLLHKNGDVQHRGMVITLNLML-AERDIAQKLMECEVLEILIVLSKDERPERMKITEAARACLTAAMDYGLIKPF 933

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Sea Lamprey
Match: unc45b (unc-45 myosin chaperone B [Source:NCBI gene;Acc:266640])

HSP 1 Score: 411.379 bits (1056), Expect = 5.712e-129
Identity = 297/924 (32.14%), Postives = 488/924 (52.81%), Query Frame = 2

Query:  287 ALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSS----VPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKT--LLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTT-IECLY-----PLCAVLANVTNSYDKPEILPEMLELAK---YAK---------------QHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSD-IRFIDKLSKVNN-WFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKL--TDETMKNVVTCAEESLEALVNHKLIKP 2950
            A++ ++ D K+LYRR  A+  +++  +A  DA++   ++P+NK++ E +R++  QI+ +++ N S   KV  MF +L   +  D  K K+  N+ +L R+ + +  I+       L +    + P +++ A  R L  L      +   + +  G +    ++ S         C++     E+I+  L   KD+ +++       K+  G V  R  +   +D+ V+ Y                    GRD+ + IL++ +P K   N   +  L + + G   +L+V      S            +  T  T MT A+LL  +Y+DL SD +RE +  +C ++V            + A   I  L QGPF+ G+ +L   G+L+ ++ L  SE    Q +A +A++ A  K ++   I  + + + ++IYK T +D +KIRALVG+CK+GS GG D S+   AEGS  +LAK CRKFL   +N       +R +S  +   + D                LLC +  T+ ++  +     PL   L   T     P IL  +L+++K   Y K                H+   H KD  +F+  R+++L+K  L   L  + + +DS+  + +ASKEL+SR++L++V   ++RG I+  GGGKALI LAL+ T+ GK  AAQALAK+ IT NP IAFPG+R  EV+RPL+ LL +EN+GLQNFESLMALTNLA ++D  R++++KEK    +E +MFE+HE +R A+ ECMCN++L  EV+E F  + NDR+KLLVL  + ++D  +  AASG LA+L+++  +   K ++V + W EI+Q +V      +Q R + +  N++ +  +   E ++ S M EI+  ++K   +D   +NV+  A E L   +N+ LIKP
Sbjct:    1 AVEDNESDVKALYRRCQAYEKMDRLDQAFRDAQRCSSIEPQNKVFVETLRKLSIQIQGKLKVNLSTDAKVEQMFKILFDENTPDGDKEKAAQNMVILARDAAGADSIYQSDGVRQLQRLISANNP-SMVLAVMRTLVGLCTAHEARATAVLRAIGMETLCRVMASDDEGISIATCKVVQAVWESIVESLP--KDHDKQQSLLLDSNKDLKGMV-VRLVEML-VDQGVSGY--------------------GRDNAMNILIKIIPRKSLKNPDNSVALKFIDYGMKHVLKVAGIVAESPGG---------LAATENTCMTAAVLLNKLYEDLRSDAERENYEKICAEYVTKYFGVSDAAGNLHAIQTISGLLQGPFDVGNKILELKGVLETMVALVASERELDQLVATEALIYAAAKSNRATFITSNGVSLLKDIYKKTTNDKIKIRALVGLCKVGSAGGTDYSLRQFAEGSMEKLAKQCRKFLCSSTN------RLRCSSRAVNASTPD----------------LLCGSPGTSSVQTCFSNRPPPLPTQLYMGTVKKKTPIILLSILDVSKIHPYKKTRFGCCCKCSVKGTVNHVTSMHPKDKKKFVNIRVKKLLKAGLVSALVCMVK-SDSAVLT-DASKELMSRVFLALVEETENRGTIVAEGGGKALIPLALEGTEVGKSKAAQALAKITITANPVIAFPGERIYEVVRPLVSLLNVENSGLQNFESLMALTNLAGINDKLRKQMLKEKAFPMIESHMFEDHEQIRAAATECMCNMVLNKEVQEMFEADGNDRMKLLVLY-SGMDDEKVQMAASGALAMLTTENTKLCAKATQVTSQWLEILQHLVMHEKKDLQVRGLAVTLNLM-SAEKGIAEKLMESEMMEILSLIAKQEGSDSESQNVIL-ARECLSKALNYGLIKP 863

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BLAST of Protein unc-45 homolog A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005772.1 (pep scaffold:Pmarinus_7.0:GL478792:23408:39519:-1 gene:ENSPMAG00000005227.1 transcript:ENSPMAT00000005772.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.485 bits (184), Expect = 1.727e-14
Identity = 44/131 (33.59%), Postives = 73/131 (55.73%), Query Frame = 2

Query:  107 KELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVN 499
            K+ GNEYFK+GD+D A + Y  G+      D        N++M +LK+ K++L  S C+ A+++    PK+  RR  A L LNK  EA+ D + ++  DP NK     ++++ K+I  Q ++ +  V  +N
Sbjct:   18 KDKGNEYFKTGDYDAANDCYTRGMEA----DPHNALLPANRAMAFLKLKKYELAESDCNLAIQLDPSYPKAFARRGAARLALNKLKEAREDFEAVLTFDPVNKQAIAELKKI-KEIYIQTKHCHLIVEHIN 143

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BLAST of Protein unc-45 homolog A vs. Ensembl Sea Lamprey
Match: ttc1 (tetratricopeptide repeat domain 1 [Source:ZFIN;Acc:ZDB-GENE-041114-80])

HSP 1 Score: 48.521 bits (114), Expect = 2.730e-6
Identity = 35/140 (25.00%), Postives = 65/140 (46.43%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNT-KDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVEN-NNSFVGKVNAMFNLL 517
             KE GN+ FK  ++ +A + Y   L          +   Y N+++ + KM   +  I  C KA+ +     ++  RR+  +   +K  EA  D + L++L+P +   +E    + +QI  + E      +GK+  + NLL
Sbjct:   62 LKESGNQLFKQAEYQQAADTYTRALKVCLRAYSSHRAVLYSNRAVAHQKMGNTEKAIQDCTKAVGLDPGYARARGRRAELYEASDKLDEALEDYRALLVLEPTHSAAREACARLPEQIHVRNEKMKEEMLGKLKDLGNLL 201

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BLAST of Protein unc-45 homolog A vs. Ensembl Sea Lamprey
Match: stip1 (stress-induced phosphoprotein 1 [Source:ZFIN;Acc:ZDB-GENE-041121-17])

HSP 1 Score: 49.2914 bits (116), Expect = 3.915e-6
Identity = 31/106 (29.25%), Postives = 52/106 (49.06%), Query Frame = 2

Query:   89 EMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDP 406
            E+    K  GN  F +GD+  A++ Y   L      +D KL  Y N++ CY K+ +F L +  C+  +++     K   R++ A   +  F++A    +K I LDP
Sbjct:  365 ELALEEKSKGNASFTNGDYPMAMKHYSEALRRN--PNDAKL--YSNRAACYTKLAEFQLALKDCEDCIRLDPTFIKGYTRKAAALEAMKDFAKAMDVYQKAIELDP 466

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BLAST of Protein unc-45 homolog A vs. Ensembl Yeast
Match: CNS1 (TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70); stimulates ATPase activity of Ssa1p; ts mutants reduce Hsp82p function, overexpression suppresses phenotypes of HSP82 ts allele and cpr7 deletion; human homolog TTC4 complements yeast cns1 mutant [Source:SGD;Acc:S000000359])

HSP 1 Score: 62.3882 bits (150), Expect = 1.629e-10
Identity = 41/112 (36.61%), Postives = 62/112 (55.36%), Query Frame = 2

Query:   89 EMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLN--YYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAK-KLILLDPKNK 415
            E+  +FK+ GNE +K+  F  A E+Y  GL  +   +D+ +N   Y N++ C L++  +   I  C KAL I+  + K  YR S AF  LNK  EA++ A      +DP+NK
Sbjct:   81 EIAENFKKQGNELYKAKRFKDARELYSKGLAVE--CEDKSINESLYANRAACELELKNYRRCIEDCSKALTINPKNVKCYYRTSKAFFQLNKLEEAKSAATFANQRIDPENK 190

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BLAST of Protein unc-45 homolog A vs. Ensembl Yeast
Match: SHE4 (Protein containing a UCS (UNC-45/CRO1/SHE4) domain; binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization [Source:SGD;Acc:S000005561])

HSP 1 Score: 60.4622 bits (145), Expect = 1.086e-9
Identity = 76/318 (23.90%), Postives = 138/318 (43.40%), Query Frame = 2

Query: 1700 RKFLRDVSNANDDG------SMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTI-ECLYPLCAVLANVTNSYDKPEILPE--------MLELAKYAKQHIPETH----EKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTG---KVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLL----RIENTGLQ---------NFESLMALTNLASVDDFHRRRIIK-----EKGLSQVEYYMFEEHEMLRRASVECMCNLL 2533
            R+ +  + N N+          V  + E LAYLSL A VK  + ++E     LL + K+  +  CLY L  ++AN++        LPE        + +L  YA    P       EK+S   I    E+ + +   ++     ++ + SP      K+ + R+  ++   +      I  GG   ++    +  D G   ++   +AL ++ I  NP + F    +L  I  L +LL     +++  L          N+E+L+ALTNLAS +      + K     +   S +E  M +E+  L+R+++E + N++
Sbjct:  340 RRIMPKIENVNESAVKLEEVPKVEMSVEALAYLSLKASVKIMIRSNESFTEILLTMIKSQKMTHCLYGLLVIMANLST-------LPEESNGSSQSINDLKNYADLKGPGADKVGAEKESKEDILLFNEKYILRTELISFLK-REMHNLSPN----CKQQVVRVIYNITRSKNFIPQCISQGGTTIILEYLANKQDIGEPIRILGCRALTRMLIFTNPGLIFKKYSALNAIPFLFELLPRSTPVDDNPLHNDEQIKLTDNYEALLALTNLASSETSDGEEVCKHIVSTKVYWSTIENLMLDENVPLQRSTLELISNMM 645

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BLAST of Protein unc-45 homolog A vs. Ensembl Yeast
Match: STI1 (Hsp90 cochaperone; regulates spatial organization of amyloid-like proteins in the cytosol, thereby buffering the proteotoxicity caused by amyloid-like proteins; interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity; interacts with Hsp90 chaperones and inhibits their ATPase activity; homolog of mammalian Hop [Source:SGD;Acc:S000005553])

HSP 1 Score: 58.5362 bits (140), Expect = 3.937e-9
Identity = 38/118 (32.20%), Postives = 62/118 (52.54%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNY--YKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEK 448
             +K+ GN  F + D+DKA+E++     TK I   E  N+  Y N+S CY  + KF   ++  ++ +KI+    K   R   A L L    EA+++ KK + LD  NK  +E + +V +
Sbjct:    7 EYKQQGNAAFTAKDYDKAIELF-----TKAIEVSETPNHVLYSNRSACYTSLKKFSDALNDANECVKINPSWSKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAKEGLDQVHR 119

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BLAST of Protein unc-45 homolog A vs. Ensembl Yeast
Match: PPT1 (Protein serine/threonine phosphatase; regulates Hsp90 chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth [Source:SGD;Acc:S000003355])

HSP 1 Score: 48.1358 bits (113), Expect = 6.077e-6
Identity = 30/119 (25.21%), Postives = 61/119 (51.26%), Query Frame = 2

Query:  107 KELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQ 463
            K  GN + K   F KA+E Y   ++     D  +  Y+ N++  + K+  F   ++ CD+A+K+   + K+ +RR+L+ + L +F +A+ D   L+   P +    + +   ++ IR +
Sbjct:   16 KNEGNVFVKEKHFLKAIEKYTEAIDL----DSTQSIYFSNRAFAHFKVDNFQSALNDCDEAIKLDPKNIKAYHRRALSCMALLEFKKARKDLNVLLKAKPNDPAATKALLTCDRFIREE 130

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BLAST of Protein unc-45 homolog A vs. Ensembl Nematostella
Match: EDO28716 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T5P6])

HSP 1 Score: 143.28 bits (360), Expect = 5.399e-39
Identity = 79/197 (40.10%), Postives = 125/197 (63.45%), Query Frame = 2

Query: 2366 LQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERF--LGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKP 2950
            L  +E+LMALTNLA ++D  R+RI+KEKG+  +E  MF++ E L+RAS ECMCN++L +EV + +  +    +RVKLL +   E ED  L +AASGGLA+L++     ++++KV  W +I++ M+      I+HR  H++ NM    +++    +V S + EI+M LS+ T   M+ +  CA  +L+  V  +LIKP
Sbjct:    2 LLQYEALMALTNLAQLNDDVRKRIVKEKGIPDIEMLMFDQDEDLKRASTECMCNMILCEEVFKLYEKVDSPTERVKLLTVYSGE-EDFGLQRAASGGLAMLTASEIVCNQVAKVGCWLDIMKEMLLSNKNEIKHRGAHVVANMTA-ANKDIATKLVESEVLEILMVLSRDTSSEMEKIRACAMRALDKAVEWELIKP 196

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BLAST of Protein unc-45 homolog A vs. Ensembl Nematostella
Match: EDO37148 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGJ7])

HSP 1 Score: 115.161 bits (287), Expect = 3.221e-26
Identity = 110/429 (25.64%), Postives = 200/429 (46.62%), Query Frame = 2

Query:  575 LIRETSNSLIWCHQDRNILLKFCQMDL---PINIIEAAHRCLSLLFLP-------SCEKT---LEIFKLHGPQYFANMIYS-SVPEHCRLAGQYLENILSGLSQIK----DYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTE-GGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDL-MSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVK 1801
            L  ++S+  +W   D      FC   +   P+++ ++    L L   P       SC      +++ K+   +   N +YS SV E  + A   LE  L  LS +     D R  ++K E      SG   F    + +    +  ++N        A  S+K+   GRD  ++ LV+  P  + +     L++    G  +LL V A      S     + I  +  T +T+M ++++L+ I+D     DK +E FR+ C   + + +    ++S +E    +  L QG  ++ + +L KSGIL  ++ L   E    + ++ + + L  + K  C ++  + +     +Y+   D +++RALVG+CKLG+ GG   +  + A+G+ L+L KS R +L   +    +    +WA+E L++LS+DADVK
Sbjct:  268 LFCQSSDPTVWPGYDGAKHATFCSFAICHSPLSLWDSVGWLLDLYLHPMYFADSWSCIYNVIQIKMSKVDIHETNKNWVYSYSVLEISKAATAALEQALVSLSHMPTLEDDLRAWRKKGE------SGQPPFEIVNKAENKAVLTSFIN--------AIRSEKICPEGRDECIDALVKVFPKNKLL----ILMFVNMKGVKELLHVAAT-----SALLIDSGIQSLTVTERTRMHISVVLSTIWDSYGHDDKQKEPFRNDCEAVIGEYMKKSSVQSHLEGCTALCALMQGAQDSAAPIL-KSGILPLVINLGTMEQRVCKIVSAETLALGTSDKVLCSTLGDEGLVALRALYQLRDDEVRVRALVGLCKLGTTGGGAVNDQTFADGATLKLYKSARSYL---TKPKKEIEFRKWAAEALSFLSMDADVK 669

HSP 2 Score: 82.4185 bits (202), Expect = 5.364e-16
Identity = 61/179 (34.08%), Postives = 90/179 (50.28%), Query Frame = 2

Query:  107 KELGNEYFKSGDFDKAL-------EMYINGLNTKDITDDEKLNYYKNQSMCYLKML------------KFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRE 586
            KE GN+YFK+GD++ AL       ++Y +G         EK   YKN++ C LK++            K++  I    KAL I   DPK+L+RRS AF    +  EA  DA+ L  L+PKN   Q  +R +  Q+  + E   +  G V+ MF  L     T + + K+L NL +L R+
Sbjct:   13 KEEGNKYFKAGDYEAALSSYAAALKLY-SGNEKDKEKQKEKAVIYKNRAACQLKLVGGRNIETGRAEEKYEAAIKDATKALDIVPNDPKALFRRSQAFEATGRLEEAFKDARTLSHLEPKNTTIQATLRRLGPQLHEKSERVRTTDGLVDEMFGALFGKGDTKERQAKALKNLVILSRD 190

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BLAST of Protein unc-45 homolog A vs. Ensembl Nematostella
Match: EDO43207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZA5])

HSP 1 Score: 57.7658 bits (138), Expect = 1.623e-8
Identity = 38/120 (31.67%), Postives = 64/120 (53.33%), Query Frame = 2

Query:  107 KELGNEYFKSGDFD----------KALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIR 436
            K+ G ++FK G +           + LE Y +    K + D  K   + N + C+LK+      I AC+KAL I K + K+L+RR  A LNL  + +++ D  +++ LDPKN+  +E ++
Sbjct:  276 KDKGTKFFKDGKYKIACRQYAVVIRVLEGYFDEEEEKAV-DPIKCAGHLNIAACHLKLGNNFKCIKACNKALDIDKENIKALFRRGKALLNLKDYEKSKEDFTQVLELDPKNREAREQLK 394

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BLAST of Protein unc-45 homolog A vs. Ensembl Nematostella
Match: EDO31207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYL2])

HSP 1 Score: 52.7582 bits (125), Expect = 8.052e-7
Identity = 30/115 (26.09%), Postives = 59/115 (51.30%), Query Frame = 2

Query:  107 KELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQ 451
            K+ GN+ F+SGD+ ++L  Y   +  K          Y N++M  +K+ ++   I  C+  + +   + K+  RR++A     K   A+ D  K++ ++P NK  +E + E+ K+
Sbjct:  219 KDKGNDAFRSGDYKESLVYYTRSIELKPTAAS-----YNNRAMAEIKLSEYAKAIEDCNTVIFLEPDNLKAFLRRAIAQKQTGKVQAAKKDLNKVLEIEPNNKRAKELLEEITKE 328

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BLAST of Protein unc-45 homolog A vs. Ensembl Nematostella
Match: EDO41747 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3C4])

HSP 1 Score: 50.0618 bits (118), Expect = 2.776e-6
Identity = 37/122 (30.33%), Postives = 59/122 (48.36%), Query Frame = 2

Query:   89 EMTTHFKELGNEYFKSGDFD-------KALEMYINGLNTKDITDDEK------LNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNK 415
            E+    K +GNE FK   ++       KAL  Y++     D+ D+ K      L  Y N + C LK+ ++   I  C++ALK+     K+L+RR  A  ++  + EA  D +K   L P +K
Sbjct:  221 EVAEKLKVIGNEQFKQQKYEVAKKKYKKALR-YLDEFQNSDMEDNAKKMAAIALPCYLNSAACKLKLAEYPSAIEDCNEALKLDANSAKALFRRGQANEHMKDYEEAMVDLQKASKLAPGDK 341

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BLAST of Protein unc-45 homolog A vs. Ensembl Medaka
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:101157856])

HSP 1 Score: 547.354 bits (1409), Expect = 3.307e-179
Identity = 339/957 (35.42%), Postives = 534/957 (55.80%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVP----EHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKL--SKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIK 2947
             KE GN  FK+GD + A+  Y   L       D  +  Y+N+S C+LK+ +++       KAL I   D K+ +RR+ AF  L++  +A  DA++   L+PKNK +QE +R++   I+ +    NS   +V  MF++L      D  + K+  NL VL R+   +      D   L++         ++ +A R L  L      +T+ I    G      ++ S         C L     E +  G+ +                        R  +   + E  ++ +   L+ LL+   +  +S  GRDS + +LV+ VP K   N   + TL   + G  K+L+V        S P  ++   L D T    M+ ++LL+ +YDDL SDK+RE F  +C +++    +   +++K+ A   + +L QGP + G+  L  SG++  ++ L  S+  ++Q+IA++A++ A  K  +   I  + + + +++YKT  +D +++RALVG+CKLGS GG D S+   AEGS  +LAK CRK+L    N +   +  RW+ EGLAYL+ DADVKE LV D+ AL  +  + K+     L+ + + L N TNSY+  +  P+M+ELAKYAKQH+PE H KD+  +++ R+ +L++  +   L  + +    SP    A KE ISR++L++V  ++ RG ++  GGGKALI LA +NTD GKV AAQALAK+AIT NP IAFPG+R  EV+RPL+ LL +  T LQNFE+LMALTNLA + +  R++IIKEK + ++E YMFEE +++R ++ ECMCNL+L  EV++ +L   NDR+KLLVL   E +D  L KAA+G LA+L+S+   + K       +W EI+QA++ C    ++HR V +++NMI    R+  E ++ S + EI+  L+K  + T   V   A++ L+  V + LI+
Sbjct:   13 LKEKGNSLFKAGDMEGAVCCYTKALKLSASKADSAV-LYRNRSACHLKLEEYNKAECDASKALDIDPSDVKARFRRAQAFQKLDRLDQAFLDAQRCAQLEPKNKAFQELLRQLGALIQQKSVQLNSTDARVQQMFSILLDDASKDSDREKAAQNLVVLSRDEGGAEQIFRNDGVKLIQKLLQSKQEEVVLSALRTLVGLCTEHQSRTMAIVNELGMDQLCAVMGSGASTVSLAACHLLQVMFEALTEGMKR----------------------EIRGKEEAMLPEP-SKELRSMLRHLLEMMPASNVSGPGRDSAINLLVKQVPRKSFKNPDNSPTLWVIDQGLKKILQVAG------SIPELSDGPPLTDNT---HMSCSVLLSKLYDDLKSDKERENFNKICEEYIQQHFSQSALDAKLRAIQTVSVLLQGPSDVGNRTLEMSGMMDAVISLCASKDVTHQQIAVEALIHAAGKAKRASFITANGVALLKDLYKTSENDRIRVRALVGLCKLGSAGGTDFSMKQFAEGSTGKLAKQCRKWL---CNESLPPTSRRWSVEGLAYLTFDADVKEDLVEDKHALTAMFELAKSEDKTVLFAVGSTLVNCTNSYEVEKPDPQMVELAKYAKQHVPEEHPKDAPSYVEKRLVKLLEAGVVSALACMVK--QESPALTEACKECISRVFLALVERQEDRGTVVAQGGGKALIPLATENTDAGKVKAAQALAKIAITSNPEIAFPGERIYEVVRPLVSLLSLNCTLLQNFEALMALTNLAGISERLRQKIIKEKAVPKIEGYMFEEQDLVRASATECMCNLVLSTEVQKLYLATGNDRLKLLVLYSGE-DDERLRKAAAGTLAMLTSEQPELCKRIPGTTTHWLEIMQALLLCEISDLRHRGVVIVQNMI-QADRDLTEKLMESEVLEILTVLAKGGEGTSDPVSKIAKDCLDKAVEYGLIR 929

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Medaka
Match: unc45b (unc-45 myosin chaperone B [Source:NCBI gene;Acc:101157061])

HSP 1 Score: 536.569 bits (1381), Expect = 3.944e-175
Identity = 340/964 (35.27%), Postives = 541/964 (56.12%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL--NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAV----AQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVP--SKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHR-RRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLA-ILSSDIRFIDKLSKVN-NWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMK-NVVTCAEESLEALVNHKLIKP 2950
              K+ GN++F++G+ +KA+E Y N +    +  D+ L    Y+N+S C+LK   +    S   KA+ +   D K+LYRR  A   L K   A  D ++   L+PKNK + E +R +  +I+++++   S   +V  MF++L   ++  D K K+ NNL VL RE + +  I+ +    +LL       P  +I AA R LS +      + + I  + G           V + C +     E I    S +              +  + S+     + Y  + A+    A+ +   L  LL+   +K +S  GRD  L +L + VP  +K+  ++++TL   + G  K+L+V          P   + + L   T  ++M  ++LL  +YDDL  D +R+ FR++C  ++   +    M+  + A N I  L QGPF+ G+A++G  G+++ ++ L  SE    Q +A++A++ + TK  +   II + + + ++IYK T ++ +KIRALVG+CKLGS GG D S+   AEGS  +LAK CRK+L    N   D    +WA EGLAYL+ DADVK+  V DE AL+ +  + K+T    +Y +   L N TNSY+K EILPE+++LAK++KQH+PE H KD   FI+ R++ L+K  +   L  + + ADSS  + + +KE+++R++L++    + RG I+  GGGKALI LAL+ TD GK  A  ALAK+A   NP IAFPG+R  EV+RPL+ LL  +  G QN+E+L  LTNLA+  +  R  +I+KEK L ++E  MFEE+E +R A+ ECMCNL+   EV+ER+L + ND++KLLVLLC E +D   I AA+G LA I ++  +   K++ V   W EI+Q +   ++P IQHR + ++ NM+ + + E  + ++ S + EI+  + K  D   + + +  A   L   ++  LIKP
Sbjct:    6 QLKDEGNKHFQAGEIEKAIECYTNAIK---VCKDKTLLAVIYRNRSACFLKKESYANAASDASKAIDVDAADIKALYRRCQALEKLGKLDMAFKDVQRCATLEPKNKTFLETLRRLGAEIQAKLKTTFSTDSRVQNMFDILFDEEMDKDKKEKAANNLIVLSREDAGAERIFQNNGVPLLLNMIDTGKP-EMIVAAVRTLSGMCTGHKARAMAIVNMVG-----------VDKICSIMALDNEEIALATSNL-------------FQCINDSLTGADTREYGKEAALVLDAAKDLKTILLALLEMIANKNVSGYGRDQALNLLSKNVPRSNKKNPDYSRTLFTIDHGLKKILKVCG------QVPELPDQLPL---TENSQMIASVLLNKLYDDLTCDPERDNFREICDQYIKSKIDPNNMDKTLHAVNTISGLLQGPFDVGNALVGHQGVMEMMVALCGSEREVDQMVAVEALIHSSTKMSRASFIITNGVSLLKDIYKKTTNEKIKIRALVGLCKLGSAGGDDYSLRQFAEGSTEKLAKQCRKWL---CNPKIDAKTRKWAIEGLAYLTNDADVKDDFVEDELALKAMFDLAKSTDKTIIYAVACTLVNCTNSYEKKEILPELVQLAKFSKQHVPEQHPKDKKDFIEKRVKRLLKAGVISALAVMVK-ADSSILT-DKTKEMLARVFLALSADPKDRGIIVAQGGGKALIPLALEGTDAGKGKACHALAKIAAVSNPTIAFPGERVYEVVRPLVSLLHTDKEGAQNYEALRGLTNLAAYSEKLRWSKIVKEKALPEIENLMFEENEKIRLAATECMCNLVTSKEVQERYLEDGNDKLKLLVLLCGEDDDKIQI-AAAGALAMITAAQKKLCTKMTLVTVQWLEILQRLCLHSNPKIQHRGLVIVYNMLDSDNNELAKKLIESELLEILTVIGKAEDNPKRQDPIDAARTCLVKAMDLGLIKP 926

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Medaka
Match: unc45a (unc-45 myosin chaperone A [Source:NCBI gene;Acc:101157856])

HSP 1 Score: 509.99 bits (1312), Expect = 2.188e-165
Identity = 312/863 (36.15%), Postives = 485/863 (56.20%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVP----EHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINW--TKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTG-SDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSD 2671
             KE GN  FK+GD + A+  Y   L       D  +  Y+N+S C+LK+ +++       KAL I   D K+ +RR+ AF  L++  +A  DA++   L+PKNK +QE +R++   I+ +    NS   +V  MF++L      D  + K+  NL VL R+   +      D   L++         ++ +A R L  L      +T+ I    G      ++ S         C L     E +  G+ +                        R  +   + E  ++ +   L+ LL+   +  +S  GRDS + +LV+ VP K   N   + TL   + G  K+L+V        S P  ++   L D T    M+ ++LL+ +YDDL SDK+RE F  +C +++    +   +++K+ A   + +L QGP + G+  L  SG++  ++ L  S+  ++Q+IA++A++ A  K  +   I  + + + +++YKT  +D +++RALVG+CKLGS GG D S+   AEGS  +LAK CRK+L    N +   +  RW+ EGLAYL+ DADVKE LV D+ AL  +  + K+     L+ + + L N TNSY+  +  P+M+ELAKYAKQH+PE H KD+  +++ R+ +L++  +   L  + +    SP    A KE ISR++L++V  ++ RG ++  GGGKALI LA +NTD GKV AAQALAK+AIT NP IAFPG+R  EV+RPL+ LL +  T LQNFE+LMALTNLA + +  R++IIKEK + ++E YMFEE +++R ++ ECMCNL+L  EV++ +L   NDR+KLLVL   E +D  L KAA+G LA+L+S+
Sbjct:   57 LKEKGNSLFKAGDMEGAVCCYTKALKLSASKADSAV-LYRNRSACHLKLEEYNKAECDASKALDIDPSDVKARFRRAQAFQKLDRLDQAFLDAQRCAQLEPKNKAFQELLRQLGALIQQKSVQLNSTDARVQQMFSILLDDASKDSDREKAAQNLVVLSRDEGGAEQIFRNDGVKLIQKLLQSKQEEVVLSALRTLVGLCTEHQSRTMAIVNELGMDQLCAVMGSGASTVSLAACHLLQVMFEALTEGMKR----------------------EIRGKEEAMLPEP-SKELRSMLRHLLEMMPASNVSGPGRDSAINLLVKQVPRKSFKNPDNSPTLWVIDQGLKKILQVAG------SIPELSDGPPLTDNT---HMSCSVLLSKLYDDLKSDKERENFNKICEEYIQQHFSQSALDAKLRAIQTVSVLLQGPSDVGNRTLEMSGMMDAVISLCASKDVTHQQIAVEALIHAAGKAKRASFITANGVALLKDLYKTSENDRIRVRALVGLCKLGSAGGTDFSMKQFAEGSTGKLAKQCRKWL---CNESLPPTSRRWSVEGLAYLTFDADVKEDLVEDKHALTAMFELAKSEDKTVLFAVGSTLVNCTNSYEVEKPDPQMVELAKYAKQHVPEEHPKDAPSYVEKRLVKLLEAGVVSALACMVK--QESPALTEACKECISRVFLALVERQEDRGTVVAQGGGKALIPLATENTDAGKVKAAQALAKIAITSNPEIAFPGERIYEVVRPLVSLLSLNCTLLQNFEALMALTNLAGISERLRQKIIKEKAVPKIEGYMFEEQDLVRASATECMCNLVLSTEVQKLYLATGNDRLKLLVLYSGE-DDERLRKAAAGTLAMLTSE 880

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Medaka
Match: unc45b (unc-45 myosin chaperone B [Source:NCBI gene;Acc:101157061])

HSP 1 Score: 508.064 bits (1307), Expect = 2.850e-165
Identity = 314/866 (36.26%), Postives = 493/866 (56.93%), Query Frame = 2

Query:  101 HFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKL--NYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNS-LIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAV----AQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVP--SKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYK-TGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSS 2668
              K+ GN++F++G+ +KA+E Y N +    +  D+ L    Y+N+S C+LK   +    S   KA+ +   D K+LYRR  A   L K   A  D ++   L+PKNK + E +R +  +I+++++   S   +V  MF++L   ++  D K K+ NNL VL RE + +  I+ +    +LL       P  +I AA R LS +      + + I  + G           V + C +     E I    S +              +  + S+     + Y  + A+    A+ +   L  LL+   +K +S  GRD  L +L + VP  +K+  ++++TL   + G  K+L+V          P   + + L   T  ++M  ++LL  +YDDL  D +R+ FR++C  ++   +    M+  + A N I  L QGPF+ G+A++G  G+++ ++ L  SE    Q +A++A++ + TK  +   II + + + ++IYK T ++ +KIRALVG+CKLGS GG D S+   AEGS  +LAK CRK+L    N   D    +WA EGLAYL+ DADVK+  V DE AL+ +  + K+T    +Y +   L N TNSY+K EILPE+++LAK++KQH+PE H KD   FI+ R++ L+K  +   L  + + ADSS  + + +KE+++R++L++    + RG I+  GGGKALI LAL+ TD GK  A  ALAK+A   NP IAFPG+R  EV+RPL+ LL  +  G QN+E+L  LTNLA+  +  R +I+KEK L ++E  MFEE+E +R A+ ECMCNL+   EV+ER+L + ND++KLLVLLC E +D   I AA+G LA++++
Sbjct:    6 QLKDEGNKHFQAGEIEKAIECYTNAIK---VCKDKTLLAVIYRNRSACFLKKESYANAASDASKAIDVDAADIKALYRRCQALEKLGKLDMAFKDVQRCATLEPKNKTFLETLRRLGAEIQAKLKTTFSTDSRVQNMFDILFDEEMDKDKKEKAANNLIVLSREDAGAERIFQNNGVPLLLNMIDTGKP-EMIVAAVRTLSGMCTGHKARAMAIVNMVG-----------VDKICSIMALDNEEIALATSNL-------------FQCINDSLTGADTREYGKEAALVLDAAKDLKTILLALLEMIANKNVSGYGRDQALNLLSKNVPRSNKKNPDYSRTLFTIDHGLKKILKVCG------QVPELPDQLPL---TENSQMIASVLLNKLYDDLTCDPERDNFREICDQYIKSKIDPNNMDKTLHAVNTISGLLQGPFDVGNALVGHQGVMEMMVALCGSEREVDQMVAVEALIHSSTKMSRASFIITNGVSLLKDIYKKTTNEKIKIRALVGLCKLGSAGGDDYSLRQFAEGSTEKLAKQCRKWL---CNPKIDAKTRKWAIEGLAYLTNDADVKDDFVEDELALKAMFDLAKSTDKTIIYAVACTLVNCTNSYEKKEILPELVQLAKFSKQHVPEQHPKDKKDFIEKRVKRLLKAGVISALAVMVK-ADSSILT-DKTKEMLARVFLALSADPKDRGIIVAQGGGKALIPLALEGTDAGKGKACHALAKIAAVSNPTIAFPGERVYEVVRPLVSLLHTDKEGAQNYEALRGLTNLAAYSEKLRSKIVKEKALPEIENLMFEENEKIRLAATECMCNLVTSKEVQERYLEDGNDKLKLLVLLCGEDDDKIQI-AAAGALAMITA 828

[Close]

BLAST of Protein unc-45 homolog A vs. Ensembl Medaka
Match: spag1a (sperm-associated antigen 1A [Source:NCBI gene;Acc:101158289])

HSP 1 Score: 68.1662 bits (165), Expect = 1.567e-11
Identity = 41/124 (33.06%), Postives = 67/124 (54.03%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENN 475
             K+ GN   K G F +AL+ Y   L  K   DD  L  Y N+++CYLK+L ++     CD A+++   + K+ YRR+LAF  L  +  A +D ++++ LDP     ++ + EV   +R  +  N
Sbjct:  258 LKQEGNGLVKKGLFQEALQKYSECLALK--PDDCAL--YTNRAICYLKLLNYEEAKQDCDSAIRLDPTNKKAFYRRALAFKGLQDYLSASSDLQEVLQLDPNVGEAEQELEEVTSLLRQSLMEN 377

HSP 2 Score: 51.6026 bits (122), Expect = 2.759e-6
Identity = 35/123 (28.46%), Postives = 58/123 (47.15%), Query Frame = 2

Query:   98 THFKELGNEYFKSGDFDKALEMY---INGLNTKDI-TDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQI 454
               K  GN  FK G F +AL  Y   I G     + + D+    Y N++ CYLK       I  C KAL++     K L RR++A+ +L ++ +A  D K ++ +D   +   + +  + K +
Sbjct:   78 ARLKNEGNHLFKHGQFGEALGKYTQAIEGCAEAGVDSPDDLCILYSNRAACYLKDGNSADCIQDCTKALELQPYSLKPLLRRAMAYESLERYRKAYVDYKTVLQMDTGIQAAHDSVHRITKML 200

[Close]

BLAST of Protein unc-45 homolog A vs. Planmine SMEST
Match: SMESG000054342.1 (SMESG000054342.1)

HSP 1 Score: 1783.07 bits (4617), Expect = 0.000e+0
Identity = 883/884 (99.89%), Postives = 883/884 (99.89%), Query Frame = 2

Query:  305 MDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYRXXXXXXXXXXXXXSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKPIK 2956
            MDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYREKKEKYETEMKEKSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSD FIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKPIK
Sbjct:    1 MDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDDMKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCLSLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLSQIKDYREKKEKYETEMKEKSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGAAAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRDLCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLLLLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAMKIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDGSMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCAVLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDGFIKTRIEELMKQNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGGGKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQLLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHEMLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAASGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMIVNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKLIKPIK 884

[Close]

BLAST of Protein unc-45 homolog A vs. Planmine SMEST
Match: SMESG000063553.1 (SMESG000063553.1)

HSP 1 Score: 63.5438 bits (153), Expect = 4.439e-10
Identity = 39/125 (31.20%), Postives = 72/125 (57.60%), Query Frame = 2

Query:   86 FEMTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEHIREVEKQIRS 460
             E +   KE+GN+YFK GD+  A+E Y   + + D  +D     + N++M ++K+  ++   + C +A+ I+    K+LYRR+   L LN   +A  D K ++ L+P NKL  + ++++EK + +
Sbjct:  102 LENSIKLKEIGNDYFKKGDYLTAVEKYSEAI-SFDRNNDV---LFTNRAMAHIKLGNYNAGETDCSQAIDINNKSVKALYRRAKCRLFLNLKDQALVDFKTVLKLEPDNKLAFKEMKDLEKDLNT 222

[Close]

BLAST of Protein unc-45 homolog A vs. Planmine SMEST
Match: SMESG000040140.1 (SMESG000040140.1)

HSP 1 Score: 60.4622 bits (145), Expect = 6.441e-9
Identity = 38/131 (29.01%), Postives = 68/131 (51.91%), Query Frame = 2

Query:  107 KELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKLILLDPKNKLYQEH----IREVEKQIRSQVENNNSFV 487
            KE GNE FK+GD D+A+  Y   L+ + I+       Y N+ + Y+K   ++  I      LK    + K+L RR+  +  ++   +A  D +K+I L P NK  + H    ++E+EK+ + ++++    V
Sbjct:  223 KEKGNEAFKAGDLDEAVIYYTRSLSIEPIS-----AVYNNRGLVYMKQKNWEEAIRDLSITLKKDPSNIKALQRRASCYSEIHNLQDAITDCRKIIKLSPNNKFAENHLSICLQELEKRSKPRLKDGKRMV 348

[Close]

BLAST of Protein unc-45 homolog A vs. Planmine SMEST
Match: SMESG000024445.1 (SMESG000024445.1)

HSP 1 Score: 54.299 bits (129), Expect = 2.065e-7
Identity = 33/102 (32.35%), Postives = 52/102 (50.98%), Query Frame = 2

Query:   83 YFEMTTH--FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLN----YYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEA 370
            Y +  TH   KE GN YF+S  F KA+  Y N +        +KL     YY N+++C+LK+  ++  IS C +AL+   M  K+ +    A++    + EA
Sbjct:   13 YIDGVTHSELKEYGNRYFESSHFQKAVTCYSNAI--------KKLPNVSIYYTNRALCHLKLQDYNKCISDCKQALEFDSMSTKAYFYMGQAYMEQGNYEEA 106

[Close]

BLAST of Protein unc-45 homolog A vs. Planmine SMEST
Match: SMESG000014898.1 (SMESG000014898.1)

HSP 1 Score: 54.6842 bits (130), Expect = 3.642e-7
Identity = 31/89 (34.83%), Postives = 52/89 (58.43%), Query Frame = 2

Query:  104 FKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCYLKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEA 370
             K   N+Y+K+ DF+KA++ Y  G+N  +  D E L  Y N++  +LK+ K    +  C+ ALKI+  + K++  +  A + LN+F EA
Sbjct:   91 MKNKANDYYKANDFEKAIKYYSKGIN--ECNDYEIL--YTNRAQAFLKIDKLKEALEDCEFALKITPTNHKAMLHKGRALVRLNRFDEA 175

The following BLAST results are available for this feature:

BLAST of Protein unc-45 homolog A vs. Ensembl Human
BLAST of Protein unc-45 homolog A vs. Ensembl Celegans
BLAST of Protein unc-45 homolog A vs. Ensembl Fly
BLAST of Protein unc-45 homolog A vs. Ensembl Zebrafish
BLAST of Protein unc-45 homolog A vs. Ensembl Xenopus
BLAST of Protein unc-45 homolog A vs. Ensembl Mouse
BLAST of Protein unc-45 homolog A vs. UniProt/SwissProt
BLAST of Protein unc-45 homolog A vs. TrEMBL
BLAST of Protein unc-45 homolog A vs. Ensembl Cavefish
BLAST of Protein unc-45 homolog A vs. Ensembl Sea Lamprey
BLAST of Protein unc-45 homolog A vs. Ensembl Yeast
BLAST of Protein unc-45 homolog A vs. Ensembl Nematostella
BLAST of Protein unc-45 homolog A vs. Ensembl Medaka
BLAST of Protein unc-45 homolog A vs. Planmine SMEST

BLAST of Protein unc-45 homolog A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
UNC45A	0.000e+0	35.66	unc-45 myosin chaperone A [Source:HGNC Symbol;Acc:...	[more]
UNC45A	0.000e+0	35.66	unc-45 myosin chaperone A [Source:HGNC Symbol;Acc:...	[more]
UNC45A	9.020e-179	35.66	unc-45 myosin chaperone A [Source:HGNC Symbol;Acc:...	[more]
UNC45B	3.808e-164	35.20	unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:...	[more]
UNC45B	5.951e-163	35.23	unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
unc-45	2.812e-110	29.61	UNC-45 [Source:UniProtKB/TrEMBL;Acc:G5EG62]	[more]
sti-1	1.896e-8	26.72	Stress-induced-phosphoprotein 1 [Source:UniProtKB...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc-45	6.164e-173	33.92	gene:FBgn0010812 transcript:FBtr0081788	[more]
unc-45	6.164e-173	33.92	gene:FBgn0010812 transcript:FBtr0347497	[more]
Stip1	1.945e-9	35.19	gene:FBgn0024352 transcript:FBtr0078131	[more]
spag	1.339e-7	29.36	gene:FBgn0015544 transcript:FBtr0072256	[more]
PpD3	1.209e-6	24.12	gene:FBgn0005777 transcript:FBtr0082129	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc45b	0.000e+0	35.48	unc-45 myosin chaperone B [Source:NCBI gene;Acc:26...	[more]
unc45a	7.333e-178	35.62	unc-45 myosin chaperone A [Source:ZFIN;Acc:ZDB-GEN...	[more]
unc45a	7.333e-178	35.62	unc-45 myosin chaperone A [Source:ZFIN;Acc:ZDB-GEN...	[more]
unc45a	5.455e-20	31.55	unc-45 myosin chaperone A [Source:ZFIN;Acc:ZDB-GEN...	[more]
unc45a	6.866e-20	31.55	unc-45 myosin chaperone A [Source:ZFIN;Acc:ZDB-GEN...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc45a	0.000e+0	37.43	unc-45 myosin chaperone A [Source:NCBI gene;Acc:49...	[more]
unc45a	0.000e+0	37.51	unc-45 myosin chaperone A [Source:NCBI gene;Acc:49...	[more]
unc45a	0.000e+0	37.49	unc-45 myosin chaperone A [Source:NCBI gene;Acc:49...	[more]
unc45a	0.000e+0	37.33	unc-45 myosin chaperone A [Source:NCBI gene;Acc:49...	[more]
unc45a	0.000e+0	37.53	unc-45 myosin chaperone A [Source:NCBI gene;Acc:49...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Unc45a	0.000e+0	35.59	unc-45 myosin chaperone A [Source:MGI Symbol;Acc:M...	[more]
Unc45a	2.789e-180	35.59	unc-45 myosin chaperone A [Source:MGI Symbol;Acc:M...	[more]
Unc45b	2.381e-171	35.41	unc-45 myosin chaperone B [Source:MGI Symbol;Acc:M...	[more]
Unc45b	3.556e-170	35.44	unc-45 myosin chaperone B [Source:MGI Symbol;Acc:M...	[more]
Unc45b	3.556e-170	35.44	unc-45 myosin chaperone B [Source:MGI Symbol;Acc:M...	[more]

BLAST of Protein unc-45 homolog A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q32PZ3\|UN45A_RAT	0.000e+0	35.70	Protein unc-45 homolog A OS=Rattus norvegicus OX=1...	[more]
sp\|Q5RAP0\|UN45A_PONAB	0.000e+0	36.12	Protein unc-45 homolog A OS=Pongo abelii OX=9601 G...	[more]
sp\|Q6DGE9\|UN45B_DANRE	0.000e+0	35.48	Protein unc-45 homolog B OS=Danio rerio OX=7955 GN...	[more]
sp\|Q68F64\|UN45B_XENLA	0.000e+0	35.98	Protein unc-45 homolog B OS=Xenopus laevis OX=8355...	[more]
sp\|Q99KD5\|UN45A_MOUSE	0.000e+0	35.59	Protein unc-45 homolog A OS=Mus musculus OX=10090 ...	[more]

BLAST of Protein unc-45 homolog A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A419PFM5	0.000e+0	39.67	Protein unc-45-like protein A OS=Clonorchis sinens...	[more]
A0A4S2JUW4	0.000e+0	39.06	TPR_REGION domain-containing protein OS=Opisthorch...	[more]
A0A1S8X2Z1	0.000e+0	39.19	Tetratricopeptide repeat protein OS=Opisthorchis v...	[more]
A0A5K3FTK2	0.000e+0	40.75	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
K1PAR4	0.000e+0	39.60	Unc-45-like protein A OS=Crassostrea gigas OX=2915...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc45a	0.000e+0	36.13	unc-45 myosin chaperone A [Source:NCBI gene;Acc:10...	[more]
unc45a	0.000e+0	36.20	unc-45 myosin chaperone A [Source:NCBI gene;Acc:10...	[more]
unc45a	5.537e-177	35.40	unc-45 myosin chaperone A [Source:NCBI gene;Acc:10...	[more]
unc45b	7.359e-136	40.37	unc-45 myosin chaperone B [Source:NCBI gene;Acc:26...	[more]
spag1a	1.850e-11	28.17	sperm associated antigen 1a [Source:NCBI gene;Acc:...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc45b	8.036e-161	34.72	unc-45 myosin chaperone B [Source:NCBI gene;Acc:26...	[more]
unc45b	5.712e-129	32.14	unc-45 myosin chaperone B [Source:NCBI gene;Acc:26...	[more]
ENSPMAT00000005772.1	1.727e-14	33.59	pep scaffold:Pmarinus_7.0:GL478792:23408:39519:-1 ...	[more]
ttc1	2.730e-6	25.00	tetratricopeptide repeat domain 1 [Source:ZFIN;Acc...	[more]
stip1	3.915e-6	29.25	stress-induced phosphoprotein 1 [Source:ZFIN;Acc:Z...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
CNS1	1.629e-10	36.61	TPR-containing co-chaperone; binds both Hsp82p (Hs...	[more]
SHE4	1.086e-9	23.90	Protein containing a UCS (UNC-45/CRO1/SHE4) domain...	[more]
STI1	3.937e-9	32.20	Hsp90 cochaperone; regulates spatial organization ...	[more]
PPT1	6.077e-6	25.21	Protein serine/threonine phosphatase; regulates Hs...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO28716	5.399e-39	40.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37148	3.221e-26	25.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43207	1.623e-8	31.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31207	8.052e-7	26.09	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41747	2.776e-6	30.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein unc-45 homolog A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc45a	3.307e-179	35.42	unc-45 myosin chaperone A [Source:NCBI gene;Acc:10...	[more]
unc45b	3.944e-175	35.27	unc-45 myosin chaperone B [Source:NCBI gene;Acc:10...	[more]
unc45a	2.188e-165	36.15	unc-45 myosin chaperone A [Source:NCBI gene;Acc:10...	[more]
unc45b	2.850e-165	36.26	unc-45 myosin chaperone B [Source:NCBI gene;Acc:10...	[more]
spag1a	1.567e-11	33.06	sperm-associated antigen 1A [Source:NCBI gene;Acc:...	[more]

BLAST of Protein unc-45 homolog A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000054342.1	0.000e+0	99.89	SMESG000054342.1	[more]
SMESG000063553.1	4.439e-10	31.20	SMESG000063553.1	[more]
SMESG000040140.1	6.441e-9	29.01	SMESG000040140.1	[more]
SMESG000024445.1	2.065e-7	32.35	SMESG000024445.1	[more]
SMESG000014898.1	3.642e-7	34.83	SMESG000014898.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016727 ID=SMED30016727|Name=Protein unc-45 homolog A|organism=Schmidtea mediterranea sexual|type=transcript|length=3073bp
AATCACTTATAAAATTATTTAGCACTAACAATTTATTTATCCCTTGTTTC
AATATATACAATAAATAACAAATATTTAAAAGTATTTTGAGATGACAACT
CATTTTAAGGAATTAGGAAATGAATATTTCAAAAGTGGCGATTTTGACAA
AGCTTTGGAAATGTATATCAATGGGCTCAACACGAAAGATATTACCGATG
ATGAAAAGTTAAATTATTATAAAAATCAATCAATGTGTTATTTAAAAATG
TTGAAATTTGATCTCGTCATATCTGCATGTGATAAAGCTTTAAAAATTTC
CAAAATGGATCCAAAATCACTTTATCGAAGAAGTTTAGCTTTCTTGAATT
TGAATAAATTCTCAGAAGCTCAGGCTGATGCAAAAAAACTTATATTACTT
GATCCAAAAAATAAATTGTATCAAGAACACATAAGAGAAGTGGAAAAACA
AATACGATCTCAAGTTGAAAATAATAATTCATTTGTTGGTAAAGTAAATG
CAATGTTTAATCTCTTAAAACAATCGGATTTAACCGATGATATGAAATTA
AAATCATTGAATAATTTAACCGTTTTAATCCGAGAAACATCCAATTCTTT
AATTTGGTGTCATCAAGATAGGAATATTTTGTTAAAATTTTGCCAAATGG
ATTTACCGATTAATATCATAGAAGCTGCTCATAGATGTCTATCTTTGCTA
TTTTTACCAAGCTGTGAAAAAACATTGGAAATATTCAAACTTCACGGACC
GCAATATTTTGCAAACATGATTTATTCCTCAGTACCAGAACATTGTCGAT
TAGCTGGTCAATATCTCGAAAATATTCTTTCTGGATTATCTCAAATCAAA
GATTACCGAGAAAAGAAAGAGAAATATGAAACGGAAATGAAAGAAAAATC
AGGAAGTGTCAATTTCCGACCATATCAAAGATATCAAATGGATGAAGCGG
TTGCACAATATGTCAATGATTGCTTGCAAACTCTTCTACAAGCTTGCAAC
AGTAAAAAATTGTCTGCAACTGGTAGAGATTCAATCCTGGAAATATTGGT
TCGATTTGTCCCTTCCAAAGAAGGAATAAATTGGACGAAAACTTTGTTGT
ACACAGAGGGTGGATTCAATAAATTGCTGGAAGTCGGTGCAGCAGCTCAC
AGATCTGAATCAACTCCCAGTCAAACCAATCATATTTCATTAATCGATAC
AACTCCTAAAACAAAAATGACTGTTGCCATATTATTGGCAAATATTTATG
ATGATTTAATGTCGGATAAGGATCGTGAAAAATTCAGAGACCTCTGTTGC
GATTTTGTTCTAGATTTATTGACTGATGAAATGATGGAGTCTAAAGTCGA
GGCAGCTAATTTGATTGGTTTGTTGTTCCAAGGACCATTTGAAGCTGGCA
GTGCCGTCTTAGGTAAATCAGGAATTTTACAGGGTCTATTATTGTTGACA
CGATCTGAAATTGCTTCATATCAGCGCATTGCATTAGACGCGATCGTACT
TGCGTGCACTAAAAAAGACAAATGTTTGTCGATAATAAAAGATGCAATTC
CAATTTTCGAGGAAATATATAAAACCGGATCGGATGCAATGAAAATTAGA
GCTCTTGTTGGAATGTGCAAACTCGGCTCAGTTGGAGGGCGAGATTCGAG
TATCCCAAGTTTGGCGGAAGGATCTAATCTTGAATTAGCGAAAAGTTGTA
GAAAATTTCTTCGTGATGTCTCCAATGCCAACGATGATGGATCTATGGTT
CGCTGGGCAAGTGAAGGCTTAGCTTATCTGAGTCTGGACGCTGATGTGAA
GGAAGCACTGGTCAATGATGAAGAAGCATTGAGAAATTTACTCTGTGTTA
CTAAGAACACAACAATAGAATGTTTGTATCCTCTTTGCGCAGTTCTAGCA
AATGTGACAAATAGTTATGATAAACCTGAAATTCTTCCGGAAATGCTCGA
ATTGGCAAAATATGCTAAACAGCACATACCAGAAACTCATGAGAAAGACA
GTGATAGATTTATAAAAACTAGAATTGAAGAATTGATGAAACAAAATCTC
TCGGTAACTTTATACAGTCTAACTCAATTGGCTGACTCGAGTCCTGGTTC
ACAAAATGCATCAAAGGAATTAATATCTCGTATTTATTTGTCCGTTGTAA
CATATGAACAACATAGAGGAGCTATTATACAAGCTGGAGGAGGAAAAGCT
TTGATATCCTTAGCTCTTGACAATACAGATACTGGAAAAGTATTTGCAGC
TCAAGCATTGGCCAAAGTTGCAATAACAATTAATCCTAGAATTGCATTTC
CAGGGCAAAGATCTCTTGAGGTGATTCGGCCGTTGATTCAATTATTACGA
ATAGAAAACACAGGATTGCAAAACTTCGAAAGCTTAATGGCTCTGACAAA
TTTAGCATCTGTTGATGATTTTCATAGACGGCGAATCATCAAAGAAAAAG
GTTTATCTCAAGTGGAATACTATATGTTTGAAGAGCATGAAATGCTGCGA
AGGGCATCGGTGGAATGCATGTGTAACCTTCTGTTACTTGACGAGGTGAA
AGAGAGATTTCTCGGCGAGGAAAACGACCGTGTGAAATTGCTAGTGCTGC
TCTGTACAGAAGTGGAAGACCTGGCCCTGATAAAAGCCGCAAGTGGCGGG
CTCGCCATTCTATCATCTGACATTCGCTTTATCGATAAACTGTCAAAAGT
GAACAATTGGTTTGAAATCGTCCAGGCAATGGTAGCCTGTGCTGATCCCG
CTATTCAGCATCGTGCCGTTCACATGTTACGCAACATGATCGTTAATGGC
AGCCGGGAATTTTGTGAATTCATTGTCAACAGTAACATGTTCGAAATAAT
AATGGCACTGTCGAAATTGACAGATGAAACCATGAAAAATGTCGTCACTT
GTGCCGAAGAATCGTTGGAGGCTCTAGTGAATCACAAGTTGATCAAACCT
ATCAAATAGAAGCCTGCTGTCAATCATTGCTCATCTCTCTCAGTTCGCAT
GTTGCCTTATTTAGCATTTATTTTGCAATTGGATCCTCTGAGATATTTAT
GCATGCTTTTATTTGCATTGAAA

protein sequence of SMED30016727-orf-1

>SMED30016727-orf-1 ID=SMED30016727-orf-1|Name=SMED30016727-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=956bp
MTTHFKELGNEYFKSGDFDKALEMYINGLNTKDITDDEKLNYYKNQSMCY
LKMLKFDLVISACDKALKISKMDPKSLYRRSLAFLNLNKFSEAQADAKKL
ILLDPKNKLYQEHIREVEKQIRSQVENNNSFVGKVNAMFNLLKQSDLTDD
MKLKSLNNLTVLIRETSNSLIWCHQDRNILLKFCQMDLPINIIEAAHRCL
SLLFLPSCEKTLEIFKLHGPQYFANMIYSSVPEHCRLAGQYLENILSGLS
QIKDYREKKEKYETEMKEKSGSVNFRPYQRYQMDEAVAQYVNDCLQTLLQ
ACNSKKLSATGRDSILEILVRFVPSKEGINWTKTLLYTEGGFNKLLEVGA
AAHRSESTPSQTNHISLIDTTPKTKMTVAILLANIYDDLMSDKDREKFRD
LCCDFVLDLLTDEMMESKVEAANLIGLLFQGPFEAGSAVLGKSGILQGLL
LLTRSEIASYQRIALDAIVLACTKKDKCLSIIKDAIPIFEEIYKTGSDAM
KIRALVGMCKLGSVGGRDSSIPSLAEGSNLELAKSCRKFLRDVSNANDDG
SMVRWASEGLAYLSLDADVKEALVNDEEALRNLLCVTKNTTIECLYPLCA
VLANVTNSYDKPEILPEMLELAKYAKQHIPETHEKDSDRFIKTRIEELMK
QNLSVTLYSLTQLADSSPGSQNASKELISRIYLSVVTYEQHRGAIIQAGG
GKALISLALDNTDTGKVFAAQALAKVAITINPRIAFPGQRSLEVIRPLIQ
LLRIENTGLQNFESLMALTNLASVDDFHRRRIIKEKGLSQVEYYMFEEHE
MLRRASVECMCNLLLLDEVKERFLGEENDRVKLLVLLCTEVEDLALIKAA
SGGLAILSSDIRFIDKLSKVNNWFEIVQAMVACADPAIQHRAVHMLRNMI
VNGSREFCEFIVNSNMFEIIMALSKLTDETMKNVVTCAEESLEALVNHKL
IKPIK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR019734	TPR_repeat
IPR011989	ARM-like
IPR011990	TPR-like_helical_dom_sf
IPR024660	UCS_central_dom
IPR013026	TPR-contain_dom
IPR016024	ARM-type_fold

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005488	binding

Vocabulary: **cellular component**
Term	Definition
GO:0048471	perinuclear region of cytoplasm
GO:0005737	cytoplasm
GO:0030018	Z disc
GO:0031672	A band

Vocabulary: **biological process**
Term	Definition
GO:0048738	cardiac muscle tissue development
GO:0048747	muscle fiber development
GO:0060538	skeletal muscle organ development
GO:0002088	lens development in camera-type eye
GO:0007275	multicellular organism development
GO:0007517	muscle organ development
GO:0007519	skeletal muscle tissue development
GO:0030154	cell differentiation
GO:0030239	myofibril assembly

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 36..56
None	No IPR available	COILS	Coil	Coil	coord: 181..201
None	No IPR available	PANTHER	PTHR45994	FAMILY NOT NAMED	coord: 2..875
IPR024660	UNC-45/Cro1/She4, central domain	PFAM	PF11701	UNC45-central	coord: 248..440 e-value: 8.6E-23 score: 81.0
IPR011989	Armadillo-like helical	GENE3D	G3DSA:1.25.10.10		coord: 56..434 e-value: 8.2E-88 score: 297.0
IPR011989	Armadillo-like helical	GENE3D	G3DSA:1.25.10.10		coord: 435..870 e-value: 1.7E-151 score: 506.9
IPR011990	Tetratricopeptide-like helical domain superfamily	GENE3D	G3DSA:1.25.40.10		coord: 1..54 e-value: 9.0E-7 score: 30.8
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 3..36 score: 8.113
IPR016024	Armadillo-type fold	SUPERFAMILY	SSF48371	ARM repeat	coord: 297..877