Nuclear pore glycoprotein p62

Overview
NameNuclear pore glycoprotein p62
Smed IDSMED30016662
Length (bp)716
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Nuclear pore glycoprotein p62 (SMED30016662) t-SNE clustered cells

Violin plots show distribution of expression levels for Nuclear pore glycoprotein p62 (SMED30016662) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Nuclear pore glycoprotein p62 (SMED30016662) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Nuclear pore glycoprotein p62 (SMED30016662) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016662

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30016662SMESG000017533.1 SmedASXL_006506SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30016662SMESG000017533.1 dd_Smed_v4_3978_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30016662SMESG000017533.1 dd_Smed_v4_3978_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Human
Match: NUP62 (nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066])

HSP 1 Score: 105.531 bits (262), Expect = 1.664e-25
Identity = 70/174 (40.23%), Postives = 104/174 (59.77%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL WI Q
Sbjct:  328 MTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPAD----------TSDPLQQICKILNAHMDSLQWIDQ 490
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Human
Match: NUP62 (nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066])

HSP 1 Score: 105.531 bits (262), Expect = 1.664e-25
Identity = 70/174 (40.23%), Postives = 104/174 (59.77%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL WI Q
Sbjct:  328 MTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPAD----------TSDPLQQICKILNAHMDSLQWIDQ 490
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Human
Match: NUP62 (nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066])

HSP 1 Score: 105.531 bits (262), Expect = 1.664e-25
Identity = 70/174 (40.23%), Postives = 104/174 (59.77%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL WI Q
Sbjct:  328 MTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPAD----------TSDPLQQICKILNAHMDSLQWIDQ 490
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Human
Match: NUP62 (nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066])

HSP 1 Score: 105.531 bits (262), Expect = 1.664e-25
Identity = 70/174 (40.23%), Postives = 104/174 (59.77%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL WI Q
Sbjct:  328 MTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPAD----------TSDPLQQICKILNAHMDSLQWIDQ 490
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Human
Match: NUP62CL (nucleoporin 62 C-terminal like [Source:HGNC Symbol;Acc:HGNC:25960])

HSP 1 Score: 85.1149 bits (209), Expect = 8.577e-20
Identity = 70/184 (38.04%), Postives = 101/184 (54.89%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRY-QYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKL 658
            MTY  LE LIN+W  EL+D E+ F+ +A ++N  D  L  NG+ I  LH ++ +  +DQ RLEQEL     QQ ELE     +E+  +  S   + Y Q  D E   IY+LAE+   +L  +  D+K +V+ +          NT E  S+  D ++Q+ RILNAHM SL WI + +  L  K+
Sbjct:    4 MTYGHLEGLINEWNLELEDQEKYFLLQATQVNAWDHTLIENGEMIRILHGEVNKVKLDQKRLEQELDFILSQQQELEFLLTYLEESTRDQS--GLHYLQDADEEHVEIYRLAESIDAQLKQMAQDLKDVVNHL----------NTFESSSDTTDPLHQICRILNAHMDSLQWIDRNSGMLRRKV 175
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Fly
Match: Nup62 (gene:FBgn0034118 transcript:FBtr0087150)

HSP 1 Score: 85.5001 bits (210), Expect = 5.417e-19
Identity = 67/188 (35.64%), Postives = 102/188 (54.26%), Query Frame = 2 
Query:   95 SNSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKL 658
            S +  ++Y QLEE INKWT E ++ E+ F  +A ++N  D  L  N  KI  L+D +++   DQ  L+QEL+    QQ ELE +   +EKE        V     D ER   Y + EN   +L  +  D+K+++D +N+ NK   G++T        D + Q+ +ILNAHM SL WI  ++ ++  KL
Sbjct:  205 STASQLSYHQLEEHINKWTLEFEEQEKVFTEQATQINAWDKLLISNNGKIVELNDAVKKVKTDQQVLDQELEFIATQQKELEDSLGPLEKEF-------VNLPRVDMERSQTYLMVENLDTQLKQMSEDLKEIIDNLNEANK---GQDT-------TDPIIQIGKILNAHMNSLQWIESQSTNISKKL 375
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Fly
Match: Nup62 (gene:FBgn0034118 transcript:FBtr0340060)

HSP 1 Score: 85.5001 bits (210), Expect = 5.417e-19
Identity = 67/188 (35.64%), Postives = 102/188 (54.26%), Query Frame = 2 
Query:   95 SNSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKL 658
            S +  ++Y QLEE INKWT E ++ E+ F  +A ++N  D  L  N  KI  L+D +++   DQ  L+QEL+    QQ ELE +   +EKE        V     D ER   Y + EN   +L  +  D+K+++D +N+ NK   G++T        D + Q+ +ILNAHM SL WI  ++ ++  KL
Sbjct:  205 STASQLSYHQLEEHINKWTLEFEEQEKVFTEQATQINAWDKLLISNNGKIVELNDAVKKVKTDQQVLDQELEFIATQQKELEDSLGPLEKEF-------VNLPRVDMERSQTYLMVENLDTQLKQMSEDLKEIIDNLNEANK---GQDT-------TDPIIQIGKILNAHMNSLQWIESQSTNISKKL 375
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Zebrafish
Match: nup62l (nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-030131-8491])

HSP 1 Score: 101.679 bits (252), Expect = 1.899e-24
Identity = 68/174 (39.08%), Postives = 102/174 (58.62%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            M+Y+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI  LH  +E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q  D ERE  Y+LAEN   +L  +  D+K++++ +N  +   D            D + Q+ +ILNAHM SL W+ Q
Sbjct:  317 MSYAQLEALINKWSSELEDQERHFLQQATQVNAWDRMLVENGEKITALHKDMEKVKLDQRRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYMQNADEERERTYKLAENVDAQLKRMSQDLKEIIEHLNTSSGPADTA----------DPLQQICKILNAHMDSLQWVEQ 479
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Zebrafish
Match: nup62l (nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-030131-8491])

HSP 1 Score: 101.679 bits (252), Expect = 2.020e-24
Identity = 68/174 (39.08%), Postives = 102/174 (58.62%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            M+Y+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI  LH  +E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q  D ERE  Y+LAEN   +L  +  D+K++++ +N  +   D            D + Q+ +ILNAHM SL W+ Q
Sbjct:  313 MSYAQLEALINKWSSELEDQERHFLQQATQVNAWDRMLVENGEKITALHKDMEKVKLDQRRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYMQNADEERERTYKLAENVDAQLKRMSQDLKEIIEHLNTSSGPADTA----------DPLQQICKILNAHMDSLQWVEQ 475
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Zebrafish
Match: nup62l (nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-030131-8491])

HSP 1 Score: 82.8037 bits (203), Expect = 8.549e-18
Identity = 56/140 (40.00%), Postives = 86/140 (61.43%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVD 529
            M+Y+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI  LH  +E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q  D ERE  Y+LAEN   +L  +  D+K++++ +N  +   D
Sbjct:  317 MSYAQLEALINKWSSELEDQERHFLQQATQVNAWDRMLVENGEKITALHKDMEKVKLDQRRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYMQNADEERERTYKLAENVDAQLKRMSQDLKEIIEHLNTSSGPAD 455
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Xenopus
Match: nup62 (nucleoporin 62kDa [Source:NCBI gene;Acc:394934])

HSP 1 Score: 103.219 bits (256), Expect = 9.768e-25
Identity = 69/174 (39.66%), Postives = 104/174 (59.77%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL+D E+ F+ +A ++N  D  L  NG++I TLH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K++++ +N      D  N           + Q+ +ILNAHM SL WI Q
Sbjct:  339 MTYAQLENLINKWSLELEDQEKHFLQQATQVNAWDRTLMQNGERITTLHREMEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKEVIEHLNTSAGPGDAGN----------PLQQICKILNAHMDSLQWIDQ 501
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Xenopus
Match: nup62 (nucleoporin 62kDa [Source:NCBI gene;Acc:394934])

HSP 1 Score: 102.834 bits (255), Expect = 1.338e-24
Identity = 69/174 (39.66%), Postives = 104/174 (59.77%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL+D E+ F+ +A ++N  D  L  NG++I TLH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K++++ +N      D  N           + Q+ +ILNAHM SL WI Q
Sbjct:  359 MTYAQLENLINKWSLELEDQEKHFLQQATQVNAWDRTLMQNGERITTLHREMEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKEVIEHLNTSAGPGDAGN----------PLQQICKILNAHMDSLQWIDQ 521
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Mouse
Match: Nup62 (nucleoporin 62 [Source:MGI Symbol;Acc:MGI:1351500])

HSP 1 Score: 108.997 bits (271), Expect = 6.074e-27
Identity = 73/194 (37.63%), Postives = 112/194 (57.73%), Query Frame = 2 
Query:   74 VTAIPNNSNSIN------MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKT 637
             TA+P +S +        MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL W+ Q +
Sbjct:  314 ATALPASSTAAGTATGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNMAGGPAD----------TSDPLQQICKILNAHMDSLQWVDQSS 496
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Mouse
Match: Nup62 (nucleoporin 62 [Source:MGI Symbol;Acc:MGI:1351500])

HSP 1 Score: 108.997 bits (271), Expect = 6.074e-27
Identity = 73/194 (37.63%), Postives = 112/194 (57.73%), Query Frame = 2 
Query:   74 VTAIPNNSNSIN------MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKT 637
             TA+P +S +        MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL W+ Q +
Sbjct:  314 ATALPASSTAAGTATGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNMAGGPAD----------TSDPLQQICKILNAHMDSLQWVDQSS 496
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Mouse
Match: Nup62 (nucleoporin 62 [Source:MGI Symbol;Acc:MGI:1351500])

HSP 1 Score: 108.997 bits (271), Expect = 6.074e-27
Identity = 73/194 (37.63%), Postives = 112/194 (57.73%), Query Frame = 2 
Query:   74 VTAIPNNSNSIN------MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKT 637
             TA+P +S +        MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL W+ Q +
Sbjct:  314 ATALPASSTAAGTATGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNMAGGPAD----------TSDPLQQICKILNAHMDSLQWVDQSS 496
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Mouse
Match: Nup62cl (nucleoporin 62 C-terminal like [Source:MGI Symbol;Acc:MGI:2685565])

HSP 1 Score: 71.2478 bits (173), Expect = 2.806e-14
Identity = 67/196 (34.18%), Postives = 105/196 (53.57%), Query Frame = 2 
Query:   53 NTVGIRPVTAIPNNS--NSIN---MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWI 625
            N  G+  V ++P+    NSI    MTY  LE + N W  +L + E+ +  +A + N  +  L  +G++IA L++++E+  IDQ RLEQEL +   QQ ELE     IE+ L++ +   +   Y ++E E IY+LAE    EL  +  D+K +V  +N      D            + + Q+ +ILNAHM+SL WI
Sbjct:   54 NNTGLINVASMPSTMTVNSIVTPVMTYGPLESMANNWHYQLQEQEKHYFYQANQFNLWNQALIESGNEIALLYNEVERVKIDQSRLEQELDIILFQQKELEQMLTPIEELLKEQN-GPLNMMYVNKEYEMIYRLAEIIDAELKRMSQDLKDIVVYLNSLAHPAD----------ATEQLEQICKILNAHMESLQWI 238
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Mouse
Match: Nup62cl (nucleoporin 62 C-terminal like [Source:MGI Symbol;Acc:MGI:2685565])

HSP 1 Score: 56.6102 bits (135), Expect = 2.747e-9
Identity = 59/173 (34.10%), Postives = 93/173 (53.76%), Query Frame = 2 
Query:   53 NTVGIRPVTAIPNNS--NSIN---MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDG-ENTNEIC 553
            N  G+  V ++P+    NSI    MTY  LE + N W  +L + E+ +  +A + N  +  L  +G++IA L++++E+  IDQ RLEQEL +   QQ ELE     IE+ L++ +   +   Y ++E E IY+LAE    EL  +  D+K +V  +N      D  E   +IC
Sbjct:   54 NNTGLINVASMPSTMTVNSIVTPVMTYGPLESMANNWHYQLQEQEKHYFYQANQFNLWNQALIESGNEIALLYNEVERVKIDQSRLEQELDIILFQQKELEQMLTPIEELLKEQN-GPLNMMYVNKEYEMIYRLAEIIDAELKRMSQDLKDIVVYLNSLAHPADATEQLEQIC 225
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. UniProt/SwissProt
Match: sp|P17955|NUP62_RAT (Nuclear pore glycoprotein p62 OS=Rattus norvegicus OX=10116 GN=Nup62 PE=1 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 1.005e-26
Identity = 73/194 (37.63%), Postives = 113/194 (58.25%), Query Frame = 2 
Query:   74 VTAIPNNSNSIN------MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKT 637
             TA+P +S ++       MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL W+ Q +
Sbjct:  313 ATALPASSTAVGTTTGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNMAGGPAD----------TSDPLQQICKILNAHMDSLQWVDQSS 495
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. UniProt/SwissProt
Match: sp|Q63850|NUP62_MOUSE (Nuclear pore glycoprotein p62 OS=Mus musculus OX=10090 GN=Nup62 PE=1 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 4.249e-26
Identity = 73/194 (37.63%), Postives = 112/194 (57.73%), Query Frame = 2 
Query:   74 VTAIPNNSNSIN------MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKT 637
             TA+P +S +        MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL W+ Q +
Sbjct:  314 ATALPASSTAAGTATGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNMAGGPAD----------TSDPLQQICKILNAHMDSLQWVDQSS 496
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. UniProt/SwissProt
Match: sp|P37198|NUP62_HUMAN (Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3)

HSP 1 Score: 105.531 bits (262), Expect = 7.992e-25
Identity = 70/174 (40.23%), Postives = 104/174 (59.77%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q+ D ERE  Y+LAEN   +L  +  D+K +++ +N      D           +D + Q+ +ILNAHM SL WI Q
Sbjct:  328 MTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQS-GTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPAD----------TSDPLQQICKILNAHMDSLQWIDQ 490
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. UniProt/SwissProt
Match: sp|Q7JXF5|NUP62_DROME (Nuclear pore glycoprotein p62 OS=Drosophila melanogaster OX=7227 GN=Nup62 PE=1 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 5.430e-18
Identity = 67/188 (35.64%), Postives = 102/188 (54.26%), Query Frame = 2 
Query:   95 SNSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKL 658
            S +  ++Y QLEE INKWT E ++ E+ F  +A ++N  D  L  N  KI  L+D +++   DQ  L+QEL+    QQ ELE +   +EKE        V     D ER   Y + EN   +L  +  D+K+++D +N+ NK   G++T        D + Q+ +ILNAHM SL WI  ++ ++  KL
Sbjct:  205 STASQLSYHQLEEHINKWTLEFEEQEKVFTEQATQINAWDKLLISNNGKIVELNDAVKKVKTDQQVLDQELEFIATQQKELEDSLGPLEKEF-------VNLPRVDMERSQTYLMVENLDTQLKQMSEDLKEIIDNLNEANK---GQDT-------TDPIIQIGKILNAHMNSLQWIESQSTNISKKL 375
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. UniProt/SwissProt
Match: sp|G0SBQ3|NSP1_CHATD (Nucleoporin NSP1 OS=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) OX=759272 GN=NSP1 PE=1 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 6.513e-12
Identity = 57/173 (32.95%), Postives = 87/173 (50.29%), Query Frame = 2 
Query:  125 LEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKEL------QQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWI 625
            ++E+I +W  +L   ++ F  +A K+ E D  L  NG+KI  L+    +       +E++L   E QQ EL A  D  E+EL      Q  S    +   PD+ERE  Y+LAE   ++LD +  D+ +M+  IN      D  NT    S  +D + Q+ R+LN H+  L WI
Sbjct:  467 MDEIITRWATDLAKYQKEFKEQAAKVMEWDRLLVENGEKIQKLYTSTYEAERASNEIERQLSNVESQQEELTAWLDRYERELDELYAKQMGSAAGEQAAGPDQERERTYKLAEKLTDQLDEMGKDLAKMIKEIN------DMSNTLSKGSKPDDPLTQIVRVLNGHLAQLQWI 633
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. TrEMBL
Match: A0A4Z2DB44 (Nuclear pore glycoprotein p62 isoform 3 OS=Schistosoma japonicum OX=6182 GN=EWB00_002737 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 3.961e-30
Identity = 90/228 (39.47%), Postives = 127/228 (55.70%), Query Frame = 2 
Query:   56 TVGIRPVTAIPNNS--NSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRIN-------------------------KQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKL 658
            T  I  VT  P+ S  +S  +TY+QLEEL+NKWT EL+D ER F  E  ++N+ D  L  N + I  +H+K+E C  +Q RLEQEL   E QQ ELE   + +E+ + +   +     + D ERE I+QLA N   EL  +L D++++ D+ N                         K++  V G N+  + SNG D+MNQ+TRILN HM SLNWIH  T ++M +L
Sbjct:  300 TTSIPSVTTAPSLSVASSQTLTYNQLEELVNKWTLELEDQERYFFDEVDRINQWDQTLICNAENITAMHEKVEMCQCEQSRLEQELDFIEGQQRELEGLLEPLERAVNE---LPPGQLHSDYEREAIFQLATNVDLELGQLLSDLREIADQTNTTTMNAVTGLNSSDNNTTTTNTTIAKESSIVSGNNSKLVSSNGGDIMNQITRILNCHMHSLNWIHHNTQEIMDRL 524
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. TrEMBL
Match: C1LG43 (Nuclear pore glycoprotein p62 OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 4.284e-30
Identity = 89/228 (39.04%), Postives = 127/228 (55.70%), Query Frame = 2 
Query:   56 TVGIRPVTAIPNNS--NSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRIN-------------------------KQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKL 658
            T  +  VT  P+ S  +S  +TY+QLEEL+NKWT EL+D ER F  E  ++N+ D  L  N + I  +H+K+E C  +Q RLEQEL   E QQ ELE   + +E+ + +   +     + D ERE I+QLA N   EL  +L D++++ D+ N                         K++  V G N+  + SNG D+MNQ+TRILN HM SLNWIH  T ++M +L
Sbjct:  276 TTSVPSVTTAPSLSVASSQTLTYNQLEELVNKWTLELEDQERYFFDEVDRINQWDQTLICNAENITAMHEKVEMCQCEQSRLEQELDFIEGQQRELEGLLEPLERAVNE---LPPGQLHSDYEREAIFQLATNVDLELGQLLSDLREIADQTNTTTMNAVTGLNSSDNNTTTTNTTITKESSIVSGNNSKLVSSNGGDIMNQITRILNCHMHSLNWIHHNTQEIMDRL 500
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. TrEMBL
Match: A0A4Z2DAX9 (Nuclear pore glycoprotein p62 isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_002737 PE=4 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 9.750e-29
Identity = 89/228 (39.04%), Postives = 125/228 (54.82%), Query Frame = 2 
Query:   56 TVGIRPVTAIPNNS--NSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRIN-------------------------KQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKL 658
            T  I  VT  P+ S  +S  +TY+QLEEL+NKWT EL+D ER F  E  ++N+ D  L  N + I  +H+K+E C  +Q RLEQEL   E QQ ELE   + +E+ + +   +     + D ERE I+QLA N   EL  +L D++++ D+ N                         K++  V G N+  + SNG D+MNQ+TRILN HM SLNWIH  T   ++ L
Sbjct:  276 TTSIPSVTTAPSLSVASSQTLTYNQLEELVNKWTLELEDQERYFFDEVDRINQWDQTLICNAENITAMHEKVEMCQCEQSRLEQELDFIEGQQRELEGLLEPLERAVNE---LPPGQLHSDYEREAIFQLATNVDLELGQLLSDLREIADQTNTTTMNAVTGLNSSDNNTTTTNTTIAKESSIVSGNNSKLVSSNGGDIMNQITRILNCHMHSLNWIHHNTRKSLSVL 500
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. TrEMBL
Match: A0A4S2LC06 (Nsp1_C domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009866 PE=4 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 2.734e-27
Identity = 81/205 (39.51%), Postives = 118/205 (57.56%), Query Frame = 2 
Query:  107 NMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEK---ELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDG-----ENTNEICSN----------------GNDVMNQVTRILNAHMKSLNWIHQKTNDLM 649
             +T+ QLEEL+NKW  EL+D ER F+ EA ++++ D  L  NG+KI TL++K++ C  +Q +LEQEL   +  Q ELE   +++E+   EL    + S      D ERE+++QLA N   EL  +L D+++M D++N     V G      NT+++ +                 G   M+QVTRILN HM SLNWIHQ T +LM
Sbjct:  349 TLTFHQLEELVNKWAHELEDQERYFMDEAERISQWDQALMSNGEKITTLYEKVDACKQEQAQLEQELDFIDGHQKELEKLLETLERTADELPPGQLHS------DFERESVFQLATNVDLELGQLLSDLREMADQVNSATSKVSGGAALARNTHDLKAKDGGLSKILGGASQPEEGIGAMHQVTRILNCHMHSLNWIHQNTQELM 547
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. TrEMBL
Match: A0A075A099 (WD_REPEATS_REGION domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_10694 PE=4 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 2.777e-27
Identity = 78/210 (37.14%), Postives = 122/210 (58.10%), Query Frame = 2 
Query:   77 TAIPNNSNSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDG-----ENTNEICSN----------------GNDVMNQVTRILNAHMKSLNWIHQKTND 643
            T++ + +    +T+ QLEEL+NKW  EL+D ER F+ EA ++++ D  L  NG+KI TL++K++ C  +Q +LEQEL   +  Q ELE   +++E+  ++     +   + D ERE+I+QLA N   EL  +L D+++M D++N     V G      NT+++ +                 G   M+QVTRILN HM SLNWIHQ T++
Sbjct:  339 TSVASVTKPSTLTFHQLEELVNKWAHELEDQERYFMDEAERISQWDQALMSNGEKITTLYEKVDACKQEQAQLEQELDFIDGHQKELEKLLETLERTAEELPPGQL---HSDFERESIFQLATNVDLELGQLLSDLREMADQVNSATSKVSGGAALARNTHDVKAKDGGLSKILGGAGQPEEGIGAMHQVTRILNCHMHSLNWIHQNTHE 545
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Cavefish
Match: nup62l (nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-030131-8491])

HSP 1 Score: 105.531 bits (262), Expect = 7.501e-26
Identity = 76/207 (36.71%), Postives = 116/207 (56.04%), Query Frame = 2 
Query:   47 THNTVGIRPV-TAIPNNSNSIN-----------MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            T  ++G++PV +A P  S   +           M+Y+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI  LH  +E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q  D ERE  Y+LAEN   +L  +  D+K++++ +N  N   D           +D + Q+ +ILNAHM SL W+ Q
Sbjct:  258 TGFSLGLKPVVSAAPAISTVASTAGITVSAAPVMSYAQLEALINKWSSELEDQERHFLQQATQVNAWDRMLVENGEKITALHKDMEKVKLDQRRLDQELDFILSQQKELEDLLAPLEESVKEQS-GTIYMQNADEERERTYKLAENVDAQLKRMSQDLKEIIEHLNTSNGPAD----------TSDPLQQICKILNAHMDSLQWVEQ 453
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Cavefish
Match: nup62l (nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-030131-8491])

HSP 1 Score: 103.219 bits (256), Expect = 4.782e-25
Identity = 78/211 (36.97%), Postives = 119/211 (56.40%), Query Frame = 2 
Query:   32 SISNSTHNTVGIRPV-TAIPNNSNSIN----------MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            SI+  T  ++G++PV +A P  S   +          M+Y+QLE LINKW+ EL+D ER F+ +A ++N  D  L  NG+KI  LH  +E+  +DQ RL+QEL     QQ ELE     +E+ +++ S  ++  Q  D ERE  Y+LAEN   +L  +  D+K++++ +N  N   D           +D + Q+ +ILNAHM SL W+ Q
Sbjct:  248 SIAAPTGFSLGLKPVVSAAPAISTVASTAGITVAAPVMSYAQLEALINKWSSELEDQERHFLQQATQVNAWDRMLVENGEKITALHKDMEKVKLDQ-RLDQELDFILSQQKELEDLLAPLEESVKEQS-GTIYMQNADEERER-YKLAENVDAQLKRMSQDLKEIIEHLNTSNGPAD----------TSDPLQQICKILNAHMDSLQWVEQ 445
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Sea Lamprey
Match: nup62l (nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-030131-8491])

HSP 1 Score: 93.2041 bits (230), Expect = 3.587e-22
Identity = 69/190 (36.32%), Postives = 111/190 (58.42%), Query Frame = 2 
Query:   92 NSNSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKLN 661
             S + ++++ QLEEL+NKW  EL++ E+ F+ +A ++N  D  L  NGD I +LH  +E+  +DQ RL+QEL     QQ ELE     +E  +++ +  ++  Q+ D ER++ Y+LAEN   +L  +  D+K++++ IN  + S           N  D + Q+ +ILNAHM SL WI Q T  L  K++
Sbjct:  345 TSAAPSLSFGQLEELLNKWGSELEEQEKHFLHQATQVNAWDRTLIENGDMITSLHKDVEKVKLDQKRLDQELDFILSQQRELEDLLVPLEDSVKEQT-GTIYMQHADEERQHTYKLAENIDAQLKRMAQDLKEIIEHINTSSSSH----------NSTDPLQQICKILNAHMDSLQWIDQNTVFLQKKVD 523
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Nematostella
Match: EDO37497 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFN3])

HSP 1 Score: 109.768 bits (273), Expect = 9.459e-28
Identity = 76/200 (38.00%), Postives = 116/200 (58.00%), Query Frame = 2 
Query:   38 SNSTHNTVGIRPVTAIPN--NSNSINMTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            + ST +TV     +A+P    S +  +TY QLE+ INKW  EL+D ER F+ +A ++N  D  L  NG+KI  L+  +E    +Q RL++EL     QQ ELE     +E EL++ S+ + + Q+ DRERE  Y LA++   +L  ++ D+K ++D +N  + +   +  NE      D + QV++ILNAHM SL WI Q
Sbjct:  275 AKSTASTV----ASAVPTALTSTAPQLTYKQLEDHINKWALELEDYERTFLDQAAQVNAWDRLLMENGEKITELNSGVESVKAEQKRLDEELNFISAQQRELEDLLKPLEDELKKNSVGTSQLQHADREREFTYGLAKDIDGQLKQMVTDLKSIIDHLNTTSST---QQENE------DPIVQVSKILNAHMNSLQWIDQ 461
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Medaka
Match: ENSORLT00000021762.2 (nucleoporin 62 [Source:NCBI gene;Acc:101161522])

HSP 1 Score: 103.219 bits (256), Expect = 5.364e-25
Identity = 70/174 (40.23%), Postives = 103/174 (59.20%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQ 631
            MTY+QLE LINKW+ EL D ER F+ +A ++N  D  L  NG+KI +LH ++E+  +DQ RL QEL     QQ ELE     +E+ +++ S  ++  Q  D ERE  Y+LAEN   +L  +  D+K++++ +N  +   D           +D + Q+ +ILNAHM SL WI Q
Sbjct:  359 MTYAQLEGLINKWSLELQDQERHFLQQATQVNAWDRMLVENGEKITSLHKEMEKVKLDQRRLNQELDFILSQQKELEDLLCPLEETVKEQS-GTIYMQNADEERERTYKLAENVDAQLKRMSQDLKEIIEHLNTSSGPAD----------TSDPLQQICKILNAHMDSLQWIDQ 521
[Close]
BLAST of Nuclear pore glycoprotein p62 vs. Planmine SMEST
Match: SMESG000017533.1 (SMESG000017533.1)

HSP 1 Score: 347.821 bits (891), Expect = 3.523e-123
Identity = 189/189 (100.00%), Postives = 189/189 (100.00%), Query Frame = 2 
Query:  110 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRXXXXXXXXXXXXXXXXAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKLNSMHLS 676
            MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRLEQELQLFEDQQGELEAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKLNSMHLS
Sbjct:    1 MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHDKIEQCSIDQIRLEQELQLFEDQQGELEAATDSIEKELQQTSIVSVRYQYPDRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSNGNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKLNSMHLS 189
The following BLAST results are available for this feature:
BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NUP621.664e-2540.23nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066][more]
NUP621.664e-2540.23nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066][more]
NUP621.664e-2540.23nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066][more]
NUP621.664e-2540.23nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066][more]
NUP62CL8.577e-2038.04nucleoporin 62 C-terminal like [Source:HGNC Symbol... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Nup625.417e-1935.64gene:FBgn0034118 transcript:FBtr0087150[more]
Nup625.417e-1935.64gene:FBgn0034118 transcript:FBtr0340060[more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
nup62l1.899e-2439.08nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-0301... [more]
nup62l2.020e-2439.08nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-0301... [more]
nup62l8.549e-1840.00nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-0301... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nup629.768e-2539.66nucleoporin 62kDa [Source:NCBI gene;Acc:394934][more]
nup621.338e-2439.66nucleoporin 62kDa [Source:NCBI gene;Acc:394934][more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nup626.074e-2737.63nucleoporin 62 [Source:MGI Symbol;Acc:MGI:1351500][more]
Nup626.074e-2737.63nucleoporin 62 [Source:MGI Symbol;Acc:MGI:1351500][more]
Nup626.074e-2737.63nucleoporin 62 [Source:MGI Symbol;Acc:MGI:1351500][more]
Nup62cl2.806e-1434.18nucleoporin 62 C-terminal like [Source:MGI Symbol;... [more]
Nup62cl2.747e-934.10nucleoporin 62 C-terminal like [Source:MGI Symbol;... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P17955|NUP62_RAT1.005e-2637.63Nuclear pore glycoprotein p62 OS=Rattus norvegicus... [more]
sp|Q63850|NUP62_MOUSE4.249e-2637.63Nuclear pore glycoprotein p62 OS=Mus musculus OX=1... [more]
sp|P37198|NUP62_HUMAN7.992e-2540.23Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9... [more]
sp|Q7JXF5|NUP62_DROME5.430e-1835.64Nuclear pore glycoprotein p62 OS=Drosophila melano... [more]
sp|G0SBQ3|NSP1_CHATD6.513e-1232.95Nucleoporin NSP1 OS=Chaetomium thermophilum (strai... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2DB443.961e-3039.47Nuclear pore glycoprotein p62 isoform 3 OS=Schisto... [more]
C1LG434.284e-3039.04Nuclear pore glycoprotein p62 OS=Schistosoma japon... [more]
A0A4Z2DAX99.750e-2939.04Nuclear pore glycoprotein p62 isoform 2 OS=Schisto... [more]
A0A4S2LC062.734e-2739.51Nsp1_C domain-containing protein OS=Opisthorchis f... [more]
A0A075A0992.777e-2737.14WD_REPEATS_REGION domain-containing protein OS=Opi... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nup62l7.501e-2636.71nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-0301... [more]
nup62l4.782e-2536.97nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-0301... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nup62l3.587e-2236.32nucleoporin 62 like [Source:ZFIN;Acc:ZDB-GENE-0301... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO374979.459e-2838.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Nuclear pore glycoprotein p62 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSORLT00000021762.25.364e-2540.23nucleoporin 62 [Source:NCBI gene;Acc:101161522][more]
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BLAST of Nuclear pore glycoprotein p62 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000017533.13.523e-123100.00SMESG000017533.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016662 ID=SMED30016662|Name=Nuclear pore glycoprotein p62|organism=Schmidtea mediterranea sexual|type=transcript|length=716bp
TATAAATGAATTTTGATTAGAACCGCAATTTTCGATATCCAATAGTACAC
ACAATACTGTGGGCATTAGGCCAGTTACAGCTATTCCTAACAATTCGAAT
TCAATAAATATGACATATAGTCAATTAGAAGAGCTAATTAACAAATGGAC
CAGAGAATTAGATGATTTAGAACGATGTTTTATCAGTGAAGCAGTTAAAA
TGAACGAACGAGACTGCCAGCTTAATATTAATGGAGATAAAATTGCAACT
CTCCATGACAAAATAGAACAGTGTAGTATAGATCAAATTAGATTAGAACA
GGAATTACAACTTTTTGAAGATCAGCAAGGAGAATTAGAAGCAGCTACTG
ATAGCATAGAAAAAGAACTTCAACAGACTTCAATAGTAAGTGTACGTTAT
CAGTATCCAGATCGAGAACGAGAAAATATTTATCAATTAGCTGAAAACTG
TCAAAATGAATTAGATAACATATTAGTTGATGTTAAGCAAATGGTTGATC
GAATTAACAAACAAAATAAATCTGTTGACGGTGAAAACACTAATGAAATA
TGTTCAAATGGTAATGATGTTATGAATCAAGTGACAAGAATTTTAAATGC
ACATATGAAATCGCTTAATTGGATTCACCAGAAAACAAATGACTTGATGA
CGAAGCTCAACAGCATGCACTTGTCATAATTGGATTTATTGAATAAATTT
CTGTTTGAATAATGAG
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protein sequence of SMED30016662-orf-1

>SMED30016662-orf-1 ID=SMED30016662-orf-1|Name=SMED30016662-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=190bp
MTYSQLEELINKWTRELDDLERCFISEAVKMNERDCQLNINGDKIATLHD
KIEQCSIDQIRLEQELQLFEDQQGELEAATDSIEKELQQTSIVSVRYQYP
DRERENIYQLAENCQNELDNILVDVKQMVDRINKQNKSVDGENTNEICSN
GNDVMNQVTRILNAHMKSLNWIHQKTNDLMTKLNSMHLS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006913nucleocytoplasmic transport
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR026010NSP1/NUP62
IPR007758Nucleoporin_NSP1_C
Vocabulary: cellular component
TermDefinition
GO:0005643nuclear pore
Vocabulary: molecular function
TermDefinition
GO:0017056structural constituent of nuclear pore
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 3..23
NoneNo IPR availableCOILSCoilCoilcoord: 111..131
NoneNo IPR availableCOILSCoilCoilcoord: 59..89
NoneNo IPR availableGENE3DG3DSA:1.20.5.170coord: 32..93
e-value: 1.3E-12
score: 49.4
IPR007758Nucleoporin, NSP1-like, C-terminalPFAMPF05064Nsp1_Ccoord: 1..91
e-value: 1.7E-19
score: 69.7
IPR026010Nucleoporin NSP1/NUP62PANTHERPTHR12084NUCLEAR PORE GLYCOPROTEIN P62-RELATEDcoord: 1..185