slc22a-10

Overview
Nameslc22a-10 (AKN21558.1)
Smed IDSMED30016659
Length (bp)1617
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of slc22a-10 (SMED30016659) t-SNE clustered cells

Violin plots show distribution of expression levels for slc22a-10 (SMED30016659) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc22a-10 (SMED30016659) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc22a-10 (SMED30016659) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016659

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30016659h1SMcG0013871 dd_Smed_v4_12547_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30016659h1SMcG0013871 dd_Smed_v4_12547_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Category 3 cellSMED30016659h1SMcG0013871 dd_Smed_v4_12547_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of slc22a-10 vs. Ensembl Human
Match: SLC22A24 (solute carrier family 22 member 24 [Source:HGNC Symbol;Acc:HGNC:28542])

HSP 1 Score: 54.299 bits (129), Expect = 4.370e-7
Identity = 97/471 (20.59%), Postives = 194/471 (41.19%), Query Frame = 2 
Query:  221 ISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVC-GRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVIL---LALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSK---LVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLN-----KIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNF 1597
            + LN  F      +T      + +DRS    T +T    VC  ++   ++ SL    ++   +++G LSD++GRK+   +    LA+  +C     F     +  +L  L   S MT I+G  +I+ +   +     +++  +  ++S   + L  +         L   +S+  +++++S   + ES RWL+I N+  +  + +  +A +N     +  L T LV   ++        K S+  L+R  K++ R+  LCFV F+I +     ++++  L      F  L  AV  +F    + ++ L      +  I+      LF  +  F  PQ +   +L+ +   +    +             L+PT  R   + +  VS   G   + L+         +M    ++  ++Y +  I++ +     +PE + +P P    D     K S +  Q +   K+  F
Sbjct:   99 LHLNGTFPNTNEPDTEPCVDGWVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCA---AFAPTFLVYCILRFLAGFSTMT-ILGNTFILSLEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAITVPFYGLILNLQHLGSNVSLFQILCGAV--TFTARCVSLLTLNHMGRRISQILFTFPVGLFILVNTFL-PQEMQ--ILRVVLATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTGAALAPLLMT-------LMAYSPHLPWISYGVFPILA-VPVILLLPETRDLPLPNTIQDVENDRKDSRNIKQEDTCMKVTQF 552
[Close]
BLAST of slc22a-10 vs. Ensembl Human
Match: SLC22A24 (solute carrier family 22 member 24 [Source:HGNC Symbol;Acc:HGNC:28542])

HSP 1 Score: 53.9138 bits (128), Expect = 6.395e-7
Identity = 67/294 (22.79%), Postives = 131/294 (44.56%), Query Frame = 2 
Query:  221 ISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVC-GRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVIL---LALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSK---LVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLN-----KIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV 1066
            + LN  F      +T      + +DRS    T +T    VC  ++   ++ SL    ++   +++G LSD++GRK+   +    LA+  +C     F     +  +L  L   S MT I+G  +I+ +   +     +++  +  ++S   + L  +         L   +S+  +++++S   + ES RWL+I N+  +  + +  +A +N     +  L T LV   ++        K S+  L+R  K++ R+  LCFV F+I +     ++++  L      F  L  AV
Sbjct:   99 LHLNGTFPNTNEPDTEPCVDGWVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCA---AFAPTFLVYCILRFLAGFSTMT-ILGNTFILSLEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAITVPFYGLILNLQHLGSNVSLFQILCGAV 388
[Close]
BLAST of slc22a-10 vs. Ensembl Human
Match: SLC22A15 (solute carrier family 22 member 15 [Source:HGNC Symbol;Acc:HGNC:20301])

HSP 1 Score: 50.0618 bits (118), Expect = 9.286e-6
Identity = 44/160 (27.50%), Postives = 70/160 (43.75%), Query Frame = 2 
Query:  401 VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEP--------------IIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNK 838
            V+ FG LSD+ GRK   +   AL +   +  GF        V   L  + +M   + L+  + +N C+                 + I+ Y + G F     +L  +  ++  +VFL+S          LFIPESPRWL  + R  +  E++  IAK N+
Sbjct:  126 VISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFL--VGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLS----------LFIPESPRWLYSQGRLSEAEEALYLIAKRNR 273
[Close]
BLAST of slc22a-10 vs. Ensembl Celegans
Match: oct-2 (Organic Cation Transporter [Source:UniProtKB/TrEMBL;Acc:Q23501])

HSP 1 Score: 73.1738 bits (178), Expect = 2.508e-13
Identity = 110/455 (24.18%), Postives = 198/455 (43.52%), Query Frame = 2 
Query:  257 NETFKM--CGKFKFDRSQIRETFITTNHAVCGRNF----IGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWI-NVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSIL-FIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNL-VEDFIEYNEWIDVS-KFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDIS-------KLHDGNYGFAFLKAAVISSFFLAPL----WIIKLWLKTYVMQVIILLITAALF--YSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICF-------YHQVPEIKCIPYPQISSDA 1531
            N T K+  C ++++D S +  T +T  + VC  N+    + + YSL  ++      + GF+SD+ GRK ++     L M     L +  E  I  VV   L   +   ++   +  +E+    +  I+ SL           ++LI   T    ++ LI     II + +L F+PESPRWL++ N+ K+  + I      NK  LP++L +    E  +W+  + K S   L+R S++++R + L  V  +  L     VI +S       ++ DGN+   FL  A+  +  L  L    +++++  K   M   ++L  + LF   S+ + +  Q      L  IF  +++  ++    +L+ F   L PT  R  A  +  + A  G   S  + I++               VT  L+ +  + CF          +PE + +P P    D+
Sbjct:  271 NATGKINRCKEWEYDTSVMDRTIVTEWNRVCDNNWSRAHVHMSYSLGYLVG---CFVGGFISDRYGRKTAITGFGILTMLFGFLLTYSKEFEIFLVVRFLLAATNEAADLAAYVLCMEVTGTKYRSIVGSLIQAPWACGYAFLALIAYLTKSWTMIHLICVLLHIISLMLLYFLPESPRWLILNNKTKQAEKIIREACHYNKSRLPSDLGLVRHAEKKKWMKHNEKPSYFHLFRSSELRFRNVVLFIVWIATALVYYGMVIALSDQSSPGRRVFDGNF---FLNNAMAGAIELPTLVFCVFLLRMGRKRSQM---LVLFGSGLFLLTSVVMVYRKQS----TLALIFMLLSKACIQGSFNILYIFTSELNPTVVRNSAVGISSMVARMGAGASGYIAILS--------------DVTMPLVPMTIFACFSLLAGCLVLLLPETQGLPLPDTILDS 698
[Close]
BLAST of slc22a-10 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782942:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6)

HSP 1 Score: 72.0182 bits (175), Expect = 6.440e-13
Identity = 101/457 (22.10%), Postives = 196/457 (42.89%), Query Frame = 2 
Query:  269 KMCGKFKFDRSQIRETFITTNHAVC----GRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVM----TEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFI---PESPRWLLIKNRHKKFYESIIAIAKLNKI-----------DLPTNLVEDFIEYNEW----IDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNY----GFAFLKAAVISSF----FLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYIC--FYHQVPEIKCIPYPQISSDA 1531
            K C  + F++  + ET +T  + VC     +    + YS+  ++     VL G  SDKIGRK +++    L     + L F N+ +   +L+ L  LS +     ++      +E+    +  ++ S+          +++LI   T   K + +I++G  + ++SI+FI   PESPRWL+++NR  +  E I    +               +LP++L  + + + E      +  K    +L+   +++YR +++C V  +  L     V+ +S           G+  L   +  +       A +W+++L  K  +M   + LIT+ LF  + +     V  H +L   F +  +  ++    +L+ F   L PT  R  A  +  + A FG+  S+ + +++         +I + IV   +  + S         +PE    P P+   DA
Sbjct:  326 KKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLG---CVLGGIASDKIGRKPTIIGFGILSSMLGVFLPF-NDYYPMFLLIRL--LSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAG--LHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDL--ELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALM---LTLITSGLFIIVAMLS--MVSGHYMLALAFMYFGKIAVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLS---------NISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 758
[Close]
BLAST of slc22a-10 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782524:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6)

HSP 1 Score: 72.0182 bits (175), Expect = 6.440e-13
Identity = 101/457 (22.10%), Postives = 196/457 (42.89%), Query Frame = 2 
Query:  269 KMCGKFKFDRSQIRETFITTNHAVC----GRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVM----TEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFI---PESPRWLLIKNRHKKFYESIIAIAKLNKI-----------DLPTNLVEDFIEYNEW----IDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNY----GFAFLKAAVISSF----FLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYIC--FYHQVPEIKCIPYPQISSDA 1531
            K C  + F++  + ET +T  + VC     +    + YS+  ++     VL G  SDKIGRK +++    L     + L F N+ +   +L+ L  LS +     ++      +E+    +  ++ S+          +++LI   T   K + +I++G  + ++SI+FI   PESPRWL+++NR  +  E I    +               +LP++L  + + + E      +  K    +L+   +++YR +++C V  +  L     V+ +S           G+  L   +  +       A +W+++L  K  +M   + LIT+ LF  + +     V  H +L   F +  +  ++    +L+ F   L PT  R  A  +  + A FG+  S+ + +++         +I + IV   +  + S         +PE    P P+   DA
Sbjct:  326 KKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLG---CVLGGIASDKIGRKPTIIGFGILSSMLGVFLPF-NDYYPMFLLIRL--LSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAG--LHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDL--ELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALM---LTLITSGLFIIVAMLS--MVSGHYMLALAFMYFGKIAVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLS---------NISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 758
[Close]
BLAST of slc22a-10 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782942:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6c.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6)

HSP 1 Score: 72.0182 bits (175), Expect = 6.447e-13
Identity = 101/457 (22.10%), Postives = 196/457 (42.89%), Query Frame = 2 
Query:  269 KMCGKFKFDRSQIRETFITTNHAVC----GRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVM----TEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFI---PESPRWLLIKNRHKKFYESIIAIAKLNKI-----------DLPTNLVEDFIEYNEW----IDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNY----GFAFLKAAVISSF----FLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYIC--FYHQVPEIKCIPYPQISSDA 1531
            K C  + F++  + ET +T  + VC     +    + YS+  ++     VL G  SDKIGRK +++    L     + L F N+ +   +L+ L  LS +     ++      +E+    +  ++ S+          +++LI   T   K + +I++G  + ++SI+FI   PESPRWL+++NR  +  E I    +               +LP++L  + + + E      +  K    +L+   +++YR +++C V  +  L     V+ +S           G+  L   +  +       A +W+++L  K  +M   + LIT+ LF  + +     V  H +L   F +  +  ++    +L+ F   L PT  R  A  +  + A FG+  S+ + +++         +I + IV   +  + S         +PE    P P+   DA
Sbjct:  328 KKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLG---CVLGGIASDKIGRKPTIIGFGILSSMLGVFLPF-NDYYPMFLLIRL--LSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAG--LHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDL--ELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALM---LTLITSGLFIIVAMLS--MVSGHYMLALAFMYFGKIAVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLS---------NISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 760
[Close]
BLAST of slc22a-10 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782524:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6)

HSP 1 Score: 72.0182 bits (175), Expect = 6.447e-13
Identity = 101/457 (22.10%), Postives = 196/457 (42.89%), Query Frame = 2 
Query:  269 KMCGKFKFDRSQIRETFITTNHAVC----GRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVM----TEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFI---PESPRWLLIKNRHKKFYESIIAIAKLNKI-----------DLPTNLVEDFIEYNEW----IDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNY----GFAFLKAAVISSF----FLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYIC--FYHQVPEIKCIPYPQISSDA 1531
            K C  + F++  + ET +T  + VC     +    + YS+  ++     VL G  SDKIGRK +++    L     + L F N+ +   +L+ L  LS +     ++      +E+    +  ++ S+          +++LI   T   K + +I++G  + ++SI+FI   PESPRWL+++NR  +  E I    +               +LP++L  + + + E      +  K    +L+   +++YR +++C V  +  L     V+ +S           G+  L   +  +       A +W+++L  K  +M   + LIT+ LF  + +     V  H +L   F +  +  ++    +L+ F   L PT  R  A  +  + A FG+  S+ + +++         +I + IV   +  + S         +PE    P P+   DA
Sbjct:  328 KKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLG---CVLGGIASDKIGRKPTIIGFGILSSMLGVFLPF-NDYYPMFLLIRL--LSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAG--LHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPSDL--ELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALM---LTLITSGLFIIVAMLS--MVSGHYMLALAFMYFGKIAVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLS---------NISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 760
[Close]
BLAST of slc22a-10 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0334870)

HSP 1 Score: 64.3142 bits (155), Expect = 1.629e-10
Identity = 73/291 (25.09%), Postives = 124/291 (42.61%), Query Frame = 2 
Query:  107 VTTIHRHSISIALFRPRFQCKIPENLLSMRDSQ----NISAYISLNQCFY--------------KQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVL-FGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWI-----IEMNSCIHE---PIIISLYFVFG-----TFSSFIVSL--ITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIE 877
            V   H+ +    L +P F+C +P    S+ +      N+S Y    +C Y               + +NET K C  + +DRS+   + +T  + VC R+ +      L ++ + L  L FG +SDK+GRK +    L L    Q+  G +  V       ++ R+ V     G+  +     +EM    +     + + ++F  G      F+ FI     + I      L+FL        W+    IPES RWLL+K R  + +  I   AK NK+++P  + E  ++
Sbjct:   30 VCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLS-YPENERCSYYDVDYTEEYLNGSIPRSSNET-KTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVL----QLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLC-----YYWI----IPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVD 305
[Close]
BLAST of slc22a-10 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0084599)

HSP 1 Score: 64.3142 bits (155), Expect = 1.629e-10
Identity = 73/291 (25.09%), Postives = 124/291 (42.61%), Query Frame = 2 
Query:  107 VTTIHRHSISIALFRPRFQCKIPENLLSMRDSQ----NISAYISLNQCFY--------------KQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVL-FGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWI-----IEMNSCIHE---PIIISLYFVFG-----TFSSFIVSL--ITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIE 877
            V   H+ +    L +P F+C +P    S+ +      N+S Y    +C Y               + +NET K C  + +DRS+   + +T  + VC R+ +      L ++ + L  L FG +SDK+GRK +    L L    Q+  G +  V       ++ R+ V     G+  +     +EM    +     + + ++F  G      F+ FI     + I      L+FL        W+    IPES RWLL+K R  + +  I   AK NK+++P  + E  ++
Sbjct:   30 VCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLS-YPENERCSYYDVDYTEEYLNGSIPRSSNET-KTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVL----QLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLC-----YYWI----IPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVD 305
[Close]
BLAST of slc22a-10 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0084598)

HSP 1 Score: 64.3142 bits (155), Expect = 1.718e-10
Identity = 73/290 (25.17%), Postives = 125/290 (43.10%), Query Frame = 2 
Query:  119 HRHSISIALFRPRFQCKIPENLLSMRDSQ----NISAYISLNQCFY--------------KQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWI-----IEM---NSCIHEPIIISLYFVFG-----TFSSFIVSL--ITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNE 886
            H+ +    L +P F+C +P    S  D      N+S Y    +C Y               + +NET K C  + +DRS+   + +T  + VCGR+F+      L ++ + L  ++FG LSDK GRK    IL A  +  Q+  G +  V       +  RL V     G+  +     +EM   +  ++  I + ++F  G      F+ F+     + I      L+F+        W+    IPES RWLL+K R      ++   A+ NK+++    + + ++  E
Sbjct:   34 HKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLS-YPENERCSYYDVDYTEEYLNGSIPRSSNET-KTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKP---ILFA-SLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMF-----YYWI----IPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGE 308
[Close]
BLAST of slc22a-10 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0334869)

HSP 1 Score: 64.3142 bits (155), Expect = 1.718e-10
Identity = 73/290 (25.17%), Postives = 125/290 (43.10%), Query Frame = 2 
Query:  119 HRHSISIALFRPRFQCKIPENLLSMRDSQ----NISAYISLNQCFY--------------KQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWI-----IEM---NSCIHEPIIISLYFVFG-----TFSSFIVSL--ITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNE 886
            H+ +    L +P F+C +P    S  D      N+S Y    +C Y               + +NET K C  + +DRS+   + +T  + VCGR+F+      L ++ + L  ++FG LSDK GRK    IL A  +  Q+  G +  V       +  RL V     G+  +     +EM   +  ++  I + ++F  G      F+ F+     + I      L+F+        W+    IPES RWLL+K R      ++   A+ NK+++    + + ++  E
Sbjct:   34 HKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLS-YPENERCSYYDVDYTEEYLNGSIPRSSNET-KTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKP---ILFA-SLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMF-----YYWI----IPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGE 308
[Close]
BLAST of slc22a-10 vs. Ensembl Fly
Match: CG17751 (gene:FBgn0038717 transcript:FBtr0273217)

HSP 1 Score: 58.9214 bits (141), Expect = 6.208e-9
Identity = 73/275 (26.55%), Postives = 122/275 (44.36%), Query Frame = 2 
Query:  107 VTTIHRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNF-IGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEV-WINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEP----IIISLYFVFGTFSSFIVSLITITTMRSKL--VFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIE-YNEWIDVSK 904
            V+++H  S +I  F P  +C  PE      D Q  S   SL  C   QF  E FK C  + F+R    E+  T    VC   + + +  S   I +    + FG+L+D+IGR  + V+      S      FV  + W +              ++  I + E  S  H      II+ +++  G   S  ++ I +T  R+ L    L + G ++  V   F+ ES  WLL K + +K  +S+  +AK N   +  ++ ++FI+ Y E ++ S+
Sbjct:   30 VSSLHYFSQTIISFTPSHRCSRPE------DYQPNST--SLLSCSVMQFDKE-FK-CTSWDFERESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIA-IWVTNWRNYLWAASLPALGMLLFPV---FLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNSQ 290
[Close]
BLAST of slc22a-10 vs. Ensembl Zebrafish
Match: slc22a21 (solute carrier family 22 member 21 [Source:ZFIN;Acc:ZDB-GENE-091118-62])

HSP 1 Score: 53.5286 bits (127), Expect = 5.116e-7
Identity = 36/118 (30.51%), Postives = 58/118 (49.15%), Query Frame = 2 
Query:  749 FIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWII 1102
            FIPESPRWLL + R ++    I   AK+N++  P  +        +   V  FS+ EL + S I+Y    LC +  ++++      ++ S LH GN     L +AV+    L   W++
Sbjct:  278 FIPESPRWLLSQGRVQEAEAIIRKAAKINRVTAPDVIFPLMQSTEDAGGVQSFSVCELLKSSNIRYMTGLLCLIWMAVSIGYCALSLNTSSLH-GNIYLNCLLSAVVEVPALLMAWLM 394
[Close]
BLAST of slc22a-10 vs. Ensembl Zebrafish
Match: slc22a21 (solute carrier family 22 member 21 [Source:ZFIN;Acc:ZDB-GENE-091118-62])

HSP 1 Score: 53.1434 bits (126), Expect = 5.342e-7
Identity = 33/106 (31.13%), Postives = 51/106 (48.11%), Query Frame = 2 
Query:  749 FIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV 1066
            FIPESPRWLL + R ++    I   AK+N++  P  +        +   V  FS+ EL + S I+Y    LC +  ++++      ++ S LH   Y    L A V
Sbjct:  278 FIPESPRWLLSQGRVQEAEAIIRKAAKINRVTAPDVIFPLMQSTEDAGGVQSFSVCELLKSSNIRYMTGLLCLIWMAVSIGYCALSLNTSSLHGNIYLNCLLSAVV 383
[Close]
BLAST of slc22a-10 vs. Ensembl Zebrafish
Match: si:dkey-166k12.1 (si:dkey-166k12.1 [Source:ZFIN;Acc:ZDB-GENE-120215-78])

HSP 1 Score: 51.9878 bits (123), Expect = 1.453e-6
Identity = 49/226 (21.68%), Postives = 103/226 (45.58%), Query Frame = 2 
Query:  308 RETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLY--FVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAF 976
            + T +T    VC +  +  + S + ++ + +  V+FG ++D+ GR+ ++++ LAL     +   F     + V L  +  ++V   II    +    +C    ++  ++  + FG     +  +  +     KL   IS+   +    I  +P S RWLL+ NR ++  + +   A +N   LP  +  +   Y      SK+++ +L R  +++ R L L ++ F
Sbjct:   95 QSTTVTEWDLVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTVQVE--RYESPQGRSKYTVVDLLRTPQMRKRALILFYIWF 318
[Close]
BLAST of slc22a-10 vs. Ensembl Zebrafish
Match: si:dkey-166k12.1 (si:dkey-166k12.1 [Source:ZFIN;Acc:ZDB-GENE-120215-78])

HSP 1 Score: 51.6026 bits (122), Expect = 1.708e-6
Identity = 49/226 (21.68%), Postives = 103/226 (45.58%), Query Frame = 2 
Query:  308 RETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLY--FVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAF 976
            + T +T    VC +  +  + S + ++ + +  V+FG ++D+ GR+ ++++ LAL     +   F     + V L  +  ++V   II    +    +C    ++  ++  + FG     +  +  +     KL   IS+   +    I  +P S RWLL+ NR ++  + +   A +N   LP  +  +   Y      SK+++ +L R  +++ R L L ++ F
Sbjct:  108 QSTTVTEWDLVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTVQVE--RYESPQGRSKYTVVDLLRTPQMRKRALILFYIWF 331
[Close]
BLAST of slc22a-10 vs. Ensembl Zebrafish
Match: slc22a16 (solute carrier family 22 member 16 [Source:ZFIN;Acc:ZDB-GENE-041001-166])

HSP 1 Score: 51.2174 bits (121), Expect = 2.876e-6
Identity = 50/246 (20.33%), Postives = 113/246 (45.93%), Query Frame = 2 
Query:  242 YKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMR--------SKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRL 952
            Y+ F N++ + CG F +D S++ ++ +T    VC R ++  +     ++ + +  ++FG  +D+IGR+    +L+A  + CQ   G       N  L  + R  + T   G + ++ +       I +  +      ++F V ++ +  +          +++  +S+   +++      PE+P +L+ K R+K+  E +  +A +N +  PT  V D  +        +  LK+  +  +++ RL
Sbjct:  112 YEFFGNKSVESCGAFVYDHSEVEQSIVTDWDLVCEREWLAKLTQPTFMLGVLIGALMFGDAADRIGRR---PVLMATSL-CQFIFGVTVAFTGNYYLFVVMRFLLATVSSGYLVVVFVYVTEFTGIKVRTWTSMHVHAAFAVGIMVVALVGYLVRVWWIYQIILTLSTSPFLLYC--WKFPETPFYLMAKGRYKEAQELLDTMAYINGLP-PTLKVSDLQD-----GCDRTPLKDNKQAMEVEKRL 345
[Close]
BLAST of slc22a-10 vs. Ensembl Mouse
Match: Slc22a7 (solute carrier family 22 (organic anion transporter), member 7 [Source:MGI Symbol;Acc:MGI:1859559])

HSP 1 Score: 57.3806 bits (137), Expect = 2.933e-8
Identity = 97/438 (22.15%), Postives = 190/438 (43.38%), Query Frame = 2 
Query:  281 KFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWII-----EMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWV-SILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEY---NEWIDVSKFSLK----ELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV-----ISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHL-VLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIII--VTYFLLNIISYICFYHQVPEIKCIPYPQISSD 1528
             +++DRS+   T  T    VC +  +  + S    I + L  V++G+LSD+ GR+    +LL  ++S  + LG ++   +N ++    R+   + + G   I+     E     H  +   +   F T    +++L+       + + L ++   +  + SI ++PES RWLL + R ++  + +   AKLN       + ED +     N+ I + + S +    +L+R S++++  L    + F +N       +D S L    Y    L  AV     I+ FFL  L      +   + +  +LL T AL + I L  +    S +  L  I K  ++    T  +    F   L PT  R    + +  +A+ G   ++L  ++      ++ D +++++  + Y  ++ ++  C    +PE K    P+   D
Sbjct:  116 GWEYDRSEFSSTIATEWDLVCQQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRR---LLLVAYVS-TLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNG----RPISEDSLSQEALNKVITMERVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRL------VGRRLTEAGMLLAT-ALTFGISLLVSSDTKSWITALVVIGKAFSEAAFTTAYL----FTSELYPTVLR---QTGMGFTALIGRLGASLAPLV------VLLDGVWLLLPKLAYGGISFLA-ACTVLLLPETKKAQLPETIQD 524
[Close]
BLAST of slc22a-10 vs. Ensembl Mouse
Match: Slc22a15 (solute carrier family 22 (organic anion/cation transporter), member 15 [Source:MGI Symbol;Acc:MGI:3607704])

HSP 1 Score: 50.447 bits (119), Expect = 4.613e-6
Identity = 44/160 (27.50%), Postives = 70/160 (43.75%), Query Frame = 2 
Query:  401 VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEP--------------IIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNK 838
            V+ FG LSD+ GR+   +   AL +   +  GF        V   L  + +M   + L+  + +N C+                 + I+ Y + G F     +L  +  ++  LVFL+S          LFIPESPRWL  + R  +  E++  IAK N+
Sbjct:  126 VISFGQLSDRFGRRKVYLTGFALDILFAVANGFSPSYEFFAVTRFL--VGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAVLVNLQGTLVFLLS----------LFIPESPRWLYSQGRLSEAEEALYFIAKRNR 273
[Close]
BLAST of slc22a-10 vs. Ensembl Mouse
Match: Slc22a7 (solute carrier family 22 (organic anion transporter), member 7 [Source:MGI Symbol;Acc:MGI:1859559])

HSP 1 Score: 49.2914 bits (116), Expect = 9.281e-6
Identity = 87/399 (21.80%), Postives = 174/399 (43.61%), Query Frame = 2 
Query:  401 VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWII-----EMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISS-----GTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTN-LVEDFIEYNEWIDVSKFSLK----ELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV-----ISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHL-VLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIII--VTYFLLNIISYICFYHQVPEIKCIPYPQISSD 1528
             V++G+LSD+ GR+    +LL  ++S  + LG ++   +N ++    R+   + + G   I+     E     H  +   +   F T    +++L+       + + L ++     G + IW    ++PES RWLL + R ++  + +   AKLN   +  + L ++ +  N+ I + + S +    +L+R S++++  L    + F +N       +D S L    Y    L  AV     I+ FFL  L      +   + +  +LL T AL + I L  +    S +  L  I K  ++    T     + F   L PT  R    + +  +A+ G   ++L  ++      ++ D +++++  + Y  ++ ++  C    +PE K    P+   D
Sbjct:   33 AVVYGYLSDRFGRRR---LLLVAYVS-TLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIW----WVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEAL--NKVITMERVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRL------VGRRLTEAGMLLAT-ALTFGISLLVSSDTKSWITALVVIGKAFSEAAFTTA----YLFTSELYPTVLR---QTGMGFTALIGRLGASLAPLV------VLLDGVWLLLPKLAYGGISFLA-ACTVLLLPETKKAQLPETIQD 400
[Close]
BLAST of slc22a-10 vs. UniProt/SwissProt
Match: sp|Q9VCA2|ORCT_DROME (Organic cation transporter protein OS=Drosophila melanogaster OX=7227 GN=Orct PE=1 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 1.633e-9
Identity = 73/291 (25.09%), Postives = 124/291 (42.61%), Query Frame = 2 
Query:  107 VTTIHRHSISIALFRPRFQCKIPENLLSMRDSQ----NISAYISLNQCFY--------------KQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVL-FGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWI-----IEMNSCIHE---PIIISLYFVFG-----TFSSFIVSL--ITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIE 877
            V   H+ +    L +P F+C +P    S+ +      N+S Y    +C Y               + +NET K C  + +DRS+   + +T  + VC R+ +      L ++ + L  L FG +SDK+GRK +    L L    Q+  G +  V       ++ R+ V     G+  +     +EM    +     + + ++F  G      F+ FI     + I      L+FL        W+    IPES RWLL+K R  + +  I   AK NK+++P  + E  ++
Sbjct:   30 VCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLS-YPENERCSYYDVDYTEEYLNGSIPRSSNET-KTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVL----QLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLC-----YYWI----IPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVD 305
[Close]
BLAST of slc22a-10 vs. UniProt/SwissProt
Match: sp|Q95R48|OCTL_DROME (Organic cation transporter-like protein OS=Drosophila melanogaster OX=7227 GN=Orct2 PE=2 SV=2)

HSP 1 Score: 64.3142 bits (155), Expect = 1.722e-9
Identity = 73/290 (25.17%), Postives = 125/290 (43.10%), Query Frame = 2 
Query:  119 HRHSISIALFRPRFQCKIPENLLSMRDSQ----NISAYISLNQCFY--------------KQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWI-----IEM---NSCIHEPIIISLYFVFG-----TFSSFIVSL--ITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNE 886
            H+ +    L +P F+C +P    S  D      N+S Y    +C Y               + +NET K C  + +DRS+   + +T  + VCGR+F+      L ++ + L  ++FG LSDK GRK    IL A  +  Q+  G +  V       +  RL V     G+  +     +EM   +  ++  I + ++F  G      F+ F+     + I      L+F+        W+    IPES RWLL+K R      ++   A+ NK+++    + + ++  E
Sbjct:   34 HKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLS-YPENERCSYYDVDYTEEYLNGSIPRSSNET-KTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKP---ILFA-SLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMF-----YYWI----IPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGE 308
[Close]
BLAST of slc22a-10 vs. UniProt/SwissProt
Match: sp|Q91WU2|S22A7_MOUSE (Solute carrier family 22 member 7 OS=Mus musculus OX=10090 GN=Slc22a7 PE=1 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 2.088e-7
Identity = 97/438 (22.15%), Postives = 190/438 (43.38%), Query Frame = 2 
Query:  281 KFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWII-----EMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWV-SILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEY---NEWIDVSKFSLK----ELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV-----ISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHL-VLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIII--VTYFLLNIISYICFYHQVPEIKCIPYPQISSD 1528
             +++DRS+   T  T    VC +  +  + S    I + L  V++G+LSD+ GR+    +LL  ++S  + LG ++   +N ++    R+   + + G   I+     E     H  +   +   F T    +++L+       + + L ++   +  + SI ++PES RWLL + R ++  + +   AKLN       + ED +     N+ I + + S +    +L+R S++++  L    + F +N       +D S L    Y    L  AV     I+ FFL  L      +   + +  +LL T AL + I L  +    S +  L  I K  ++    T  +    F   L PT  R    + +  +A+ G   ++L  ++      ++ D +++++  + Y  ++ ++  C    +PE K    P+   D
Sbjct:  116 GWEYDRSEFSSTIATEWDLVCEQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRR---LLLVAYVS-TLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNG----RPISEDSLSQEALNKVITMERVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRL------VGRRLTEAGMLLAT-ALTFGISLLVSSDTKSWITALVVIGKAFSEAAFTTAYL----FTSELYPTVLR---QTGMGFTALIGRLGASLAPLV------VLLDGVWLLLPKLAYGGISFLA-ACTVLLLPETKKAQLPETIQD 524
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BLAST of slc22a-10 vs. UniProt/SwissProt
Match: sp|Q5RLM2|S22A7_RAT (Solute carrier family 22 member 7 OS=Rattus norvegicus OX=10116 GN=Slc22a7 PE=1 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 2.938e-7
Identity = 64/278 (23.02%), Postives = 125/278 (44.96%), Query Frame = 2 
Query:  281 KFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWII-----EMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISS-----GTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLN-----KIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV 1066
             +++DRS+   T  T    VC +  +  I S    I + +  V++G+LSD+ GR+    +LL  ++S  + LG ++   IN ++  + R    + + G   I+     E     H  +   +  VF +    +++L+       + + L ++     G + IW    ++PES RWLL + R ++  + +++ AKLN     +  L    + + +       + + S  +L+R S++++  L    V F +N       +D+S L    Y    L  AV
Sbjct:  116 GWEYDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRR---LLLVAYVS-SLVLGLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIW----WVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEGSLSQEALNNVVTMER--ALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQTQLLFGAV 383
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BLAST of slc22a-10 vs. UniProt/SwissProt
Match: sp|Q8N4F4|S22AO_HUMAN (Steroid transmembrane transporter SLC22A24 OS=Homo sapiens OX=9606 GN=SLC22A24 PE=1 SV=2)

HSP 1 Score: 54.299 bits (129), Expect = 2.099e-6
Identity = 97/471 (20.59%), Postives = 194/471 (41.19%), Query Frame = 2 
Query:  221 ISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVC-GRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVIL---LALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSK---LVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLN-----KIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNF 1597
            + LN  F      +T      + +DRS    T +T    VC  ++   ++ SL    ++   +++G LSD++GRK+   +    LA+  +C     F     +  +L  L   S MT I+G  +I+ +   +     +++  +  ++S   + L  +         L   +S+  +++++S   + ES RWL+I N+  +  + +  +A +N     +  L T LV   ++        K S+  L+R  K++ R+  LCFV F+I +     ++++  L      F  L  AV  +F    + ++ L      +  I+      LF  +  F  PQ +   +L+ +   +    +             L+PT  R   + +  VS   G   + L+         +M    ++  ++Y +  I++ +     +PE + +P P    D     K S +  Q +   K+  F
Sbjct:   99 LHLNGTFPNTNEPDTEPCVDGWVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCA---AFAPTFLVYCILRFLAGFSTMT-ILGNTFILSLEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAITVPFYGLILNLQHLGSNVSLFQILCGAV--TFTARCVSLLTLNHMGRRISQILFTFPVGLFILVNTFL-PQEMQ--ILRVVLATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTGAALAPLLMT-------LMAYSPHLPWISYGVFPILA-VPVILLLPETRDLPLPNTIQDVENDRKDSRNIKQEDTCMKVTQF 552
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BLAST of slc22a-10 vs. TrEMBL
Match: A0A0H3YK97 (Slc22a-10 OS=Schmidtea mediterranea OX=79327 GN=slc22a-10 PE=2 SV=1)

HSP 1 Score: 1038.48 bits (2684), Expect = 0.000e+0
Identity = 529/532 (99.44%), Postives = 530/532 (99.62%), Query Frame = 2 
Query:   20 MYYDSIVKIFSRKKXXXXXXXXXXXXVCYVTTIHRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNFNKKYEF 1615
            M YDSIVKIFSRKKSFLILSLFFISFVCYVTTIHRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLIT ALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVR+ITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNFNKKYEF
Sbjct:    1 MDYDSIVKIFSRKKSFLILSLFFISFVCYVTTIHRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITTALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRMITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNFNKKYEF 532
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BLAST of slc22a-10 vs. TrEMBL
Match: A0A0H3YFD1 (Slc22a-9 OS=Schmidtea mediterranea OX=79327 GN=slc22a-9 PE=2 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 4.297e-25
Identity = 130/514 (25.29%), Postives = 220/514 (42.80%), Query Frame = 2 
Query:  125 HSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVI-----ILLI--TAALFYSICLFFNP----QVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISY-------ICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNFNKKYE 1612
             +I  ALF P F+CK          +      +S +QC      N T   C ++ F    I  T ++    VC   ++G +  ++      L  L GF+SD+ GRK  V++ L L     + L         +    L  LS     I ++W+IE  S    P I S Y+ + T +  +  + +      +L  L +    + ++ I F+PESPRWL + NR  +  ES+  ++K+N++       + ++E      V + ++    + +  + R +   F AFSINL   + ++DI  L    Y         +S F L  + +  L L  YV++ I      LLI    +L   I +FF+     Q +  +VL  + K    +  + IM+    +V  L PTTHR F  +LL++S      FS  V I  +             +++YFL  +I +       +  Y  +PE K +P P+   D  +++ G E+E     + K   FN   +
Sbjct:   36 QNILFALFIPNFKCKF---------NSKSKFIVSKDQC--SILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPLVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVEN----LVKEGNICVACKDTDFQSRSITALFCAFSINLIYSSMLVDIGILSSNMY---------LSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMV----YVNELFPTTHRSFGITLLLISNFLS--FSGAVLINRLS------------VISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVD 507
[Close]
BLAST of slc22a-10 vs. TrEMBL
Match: A0A0H3YF34 (Slc22a-7 OS=Schmidtea mediterranea OX=79327 GN=slc22a-7 PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 4.410e-22
Identity = 129/509 (25.34%), Postives = 226/509 (44.40%), Query Frame = 2 
Query:  125 HSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIK---YRLLALC--FVAFSINLFPPNFVIDISKLHDGNY------GFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMIL----LFSFVINLMPTTHR----GFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFN 1594
             ++ +++  P F C+  E       S  I   IS +QC      N +   C  + F      +T ++    VC   ++G +  LL      +  +FG+L+DK GRK+  +I L++       L F   +  ++        S     I  +W++EM +     +  S ++++G+ +  +  L    T   +L  LIS    I++V ILF+PESPRWL +KN+ ++  ES+  IA +NK+DL     E  IE          + KE  +++  K   +  LA    F  FSI++     +ID++ L    Y      G      A++S            +L  Y  +   ++   ++F SI +F +  +      Q IF+ I  ++ K ++I     +  +   L PTTHR    G    +L+++     Y + L      +F G      +I ++ YFLLN+IS    +  +PE K +P P+   D  ++ K    E ++EY E ++N
Sbjct:   36 QNLLVSIQTPNFTCQYNET------SHQIQ--ISKDQC--TMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEK---------TTKESNKWNAFKDNNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLS------------YLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKL-----NQFYG------FIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVK----EREQEYLEYMYN 498
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BLAST of slc22a-10 vs. TrEMBL
Match: A0A0H3YJ93 (Slc22a-1 OS=Schmidtea mediterranea OX=79327 GN=slc22a-1 PE=2 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 3.350e-19
Identity = 126/508 (24.80%), Postives = 212/508 (41.73%), Query Frame = 2 
Query:  119 HRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFI-----EYNEW--IDVSKFSLKELWRYSKIKYRLLALCF-VAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHR--GFASSLLV-----VSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDEL------QREYE 1579
               +I I+ + P++ C        + +S      IS +QC      + +  +C K+ F    +  T ++    VC    +G I  ++         + G+ SDK GRK   +  L L       + F  +V  N++   L  +S        +W++EM          S  + +G  +  +  L    T   ++  LIS    I++  IL  PESPRWL + NR  +  +S+  IA++NKID   N  + F+     E+N W  +    FSL+            + L F + FSINL      +++  L +  Y   FL    +  F    L  + L         I++    ++F  I +FF+  ++   V++ IF  IA+  + T       +V  L PT+HR  GFAS  L       +A++ N  S      TV F        ++ +V YF+L  ++    Y  +PE K +P P+   D  +++   E E       +RE E
Sbjct:   34 QMQNILISTYTPKYTC--------LYNSSFSKISISADQC--NMIIDGSTIVCNKWNFSYEPVGRTMMSDFSLVCDYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYDQIFVPKTKDEHNTWKALKDKTFSLR------------MTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLG--LMEFPGILLSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAVYINKLS------TVLF--------FLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREME 503
[Close]
BLAST of slc22a-10 vs. TrEMBL
Match: A0A0H3YF32 (Slc22a-2 OS=Schmidtea mediterranea OX=79327 GN=slc22a-2 PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 8.450e-16
Identity = 105/447 (23.49%), Postives = 209/447 (46.76%), Query Frame = 2 
Query:  125 HSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGF----LSDKIGRKVSVVILLALHMSCQMTLGFV--NEVWINVVLMSLKRLSVMTEI-IGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWV-SILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLK--ELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV-ISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMI-----------LLFSFVIN-LMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKF 1396
              ++ AL+ P+F C +     ++R+S N+   IS +QC Y+   N+++  C ++ F++  +R T I   + VC R F    Y  L      +  LF F    LSD IG+++  ++++++ +S  +T+G +   ++W  +VL  +  +     + +    +IE+    H  +  + ++   +F    V+L        + ++++S  T I +V    F+PE+PRWL++  R  + ++++  IAK+NK  L         E+N+W  + + + K   L ++  + YR L L F  ++ +        D++   +  +   F+   V + +  L+ +   KL  K  V  +  L I       ICL   P + +  +     K + Q  LK  +            L+F  + N L+PTT R  A SL+ ++   G+ F+ ++  + ++F
Sbjct:   36 QGLTFALYEPKFSCLVKNISSTIRNSTNL---ISKDQCQYRLSVNDSWNKCDQWTFEKRFMRNTLINELNLVCDRAF----YRELIFTTFFVGCLFSFPFSILSDSIGKRL--LLIVSIFLSTIITIGQMVSYQIWQQLVLSFVSGVCKSVYVSLAYTTLIEIIPVSHIDLAATNFWNLYSFGYMSVALFAYIFRSWRQIYILSLITSIFYVLYFWFVPETPRWLMLNKRRNEAFKTMSFIAKINKCTLNKE------EFNKWKPIQQVTGKFWNLLKHKTMIYRFLILNFAGWAFSFAYIGSATDLTFASENIFITTFVMGLVELPTGPLSGIMANKLGRKKSVSALSGLGI-------ICLIIMPFIEADSL-----KSVWQPWLKVCLAMGAKLGFSSAWLIFDIITNELIPTTDRNTAMSLVYITVGLGSIFAPMIHSVLLQF 455
[Close]
BLAST of slc22a-10 vs. Ensembl Cavefish
Match: si:dkey-166k12.1 (organic cation transporter protein-like [Source:NCBI gene;Acc:103028750])

HSP 1 Score: 53.9138 bits (128), Expect = 2.581e-7
Identity = 66/279 (23.66%), Postives = 121/279 (43.37%), Query Frame = 2 
Query:  173 PENLLSMRDSQNISAYISL---NQCFYKQFTNETFKMCGKFKFDRSQ--IRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTE-----IIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAF 976
            P    S+R + N SA IS    + C      N + +   +  +  SQ     T +T    VCGR  +  I S + ++ + +  V+FG ++D+ GR+ ++++ LAL     +   F     + V+L  L   ++        ++G  W       +    I + YF FG     +  +  +     KL   IS+   +    I  +P S RWLL+ +R ++    +   A +N    PT +  D+ +  E    S+ S+ +L R  +++ R L L ++ F
Sbjct:   46 PHRCRSLRLA-NSSAGISAGHADACSAGSAENRSARSACESGWVYSQDVFESTTVTEWDLVCGRASLNSICSSIYMLGLLVGAVVFGAMADRYGRRFALLLSLALQTVFGVAAAFAPNFLVYVILRFLIGTTISGIIINAFVLGTEWTSTKRRMLAG--IFTDYF-FGLGYMLLAGIAYLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNDRKEEAIVLLRKAAMVNGRSFPTTVQLDWCDETE--GRSQHSVADLVRTPEMRKRALILYYIWF 318
[Close]
BLAST of slc22a-10 vs. Ensembl Cavefish
Match: si:dkey-166k12.1 (organic cation transporter protein-like [Source:NCBI gene;Acc:103028750])

HSP 1 Score: 53.5286 bits (127), Expect = 3.629e-7
Identity = 63/268 (23.51%), Postives = 116/268 (43.28%), Query Frame = 2 
Query:  206 NISAYISL---NQCFYKQFTNETFKMCGKFKFDRSQ--IRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTE-----IIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAF 976
            N SA IS    + C      N + +   +  +  SQ     T +T    VCGR  +  I S + ++ + +  V+FG ++D+ GR+ ++++ LAL     +   F     + V+L  L   ++        ++G  W       +    I + YF FG     +  +  +     KL   IS+   +    I  +P S RWLL+ +R ++    +   A +N    PT +  D+ +  E    S+ S+ +L R  +++ R L L ++ F
Sbjct:   73 NSSAGISAGHADACSAGSAENRSARSACESGWVYSQDVFESTTVTEWDLVCGRASLNSICSSIYMLGLLVGAVVFGAMADRYGRRFALLLSLALQTVFGVAAAFAPNFLVYVILRFLIGTTISGIIINAFVLGTEWTSTKRRMLAG--IFTDYF-FGLGYMLLAGIAYLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNDRKEEAIVLLRKAAMVNGRSFPTTVQLDWCDETE--GRSQHSVADLVRTPEMRKRALILYYIWF 335
[Close]
BLAST of slc22a-10 vs. Ensembl Cavefish
Match: SLC22A2 (solute carrier family 22 member 2-like [Source:NCBI gene;Acc:103036098])

HSP 1 Score: 53.5286 bits (127), Expect = 4.110e-7
Identity = 61/236 (25.85%), Postives = 106/236 (44.92%), Query Frame = 2 
Query:  308 RETFITTNHAVCGRNF-IGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSV----------MTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSI-LFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFS 979
            RE+F+T    VC   + + +  ++L I  +   +  G+L+DK GRK+S ++   L+    + +         VV  +L    V          MTE +G              ++  ++F FG     +++ +       ++ F +     II++S   F+PESPRWLL +N+  +  E   A+AK NK  L  N +++  + N   + S  S  +L R  KI+   L L F  F+
Sbjct:  133 RESFVTEFDLVCDDAWLVDVFQAVLGIGFLVGSITIGYLADKFGRKMSFLLSNILNAVTGILVAISPNYISLVVFRALHGFGVKGGWMAAYVLMTETVG--------------VLFQMFFSFGLLLLALIAYLIPNWRWLQVAFTVP---YIIFLSYYWFVPESPRWLLSQNKSSRAVEVTQAMAKENKKTLSQN-IKNLKDDNA--ETSTGSFMDLIRTPKIRKHTLILSFNWFT 348
[Close]
BLAST of slc22a-10 vs. Ensembl Sea Lamprey
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92])

HSP 1 Score: 55.8398 bits (133), Expect = 1.735e-8
Identity = 97/459 (21.13%), Postives = 193/459 (42.05%), Query Frame = 2 
Query:  281 KFKFDRSQIRETFITTNHAVCGRNFI-GLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVM----------TEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLIT--ITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWID-VSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVIN--LMPTTHRGFA----SSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQ----REYEEK 1585
             ++FD  +   T ++    VC   ++  L  +LL +  +   +L G++SD+ GR+ S+++ + +     + + F       V + +L+ +  M          TE +G          +H  +++ ++F FG     ++S I   + T R  L   ++   ++++     +PESPRWL+ +NR ++ +  +  IA +N  +L  N+ ++F E     +     S+ +L R +KI+   + L    F + +      +    + D  Y  AFL   +       P  ++ + L   V + + + +   L    CL     ++ H +       +    L   M      ++N  L PT  R  A    SSL  +  I   +   L R+ T+ +R       ++ +V +  L II        +PE   +P P+ + DA  I K  + + +    R++E K
Sbjct:  130 GWEFDTEKTGLTLVSEFDLVCENAWLLDLSQALLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAPNYAAFVCMRTLQGIFNMGSWTTVFVTATEFVG----SGQRRVVH--MVLQMFFSFGVI---MLSGIAYYLRTWR-YLQLALTLPNVVLFSYYWLLPESPRWLISQNRKEQAFGVLKKIASVNGRELSDNIRKNFEEVTRADEKAGNPSIADLMRSAKIRKYTVVLMIYWFVVGVVYQGLAMSTGNIGDDVY-LAFLMGGLAE----IPGALMVIALIDRVGRRLPMCVAPGLSGLACL--ATALVPHDIGWLNITLVTLGRLGLTMAYEMVTLVNNELYPTHLRNMAMSTCSSLSGIGGIVAPFV--LYRLYTI-WR-------HLPMVIFGTLAIIGGFVIL-LLPETNGLPLPETTEDAENISKNQKMKQKMLRSRKFETK 560
[Close]
BLAST of slc22a-10 vs. Ensembl Sea Lamprey
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971])

HSP 1 Score: 48.9062 bits (115), Expect = 1.378e-6
Identity = 54/261 (20.69%), Postives = 106/261 (40.61%), Query Frame = 2 
Query:  152 PRFQCKIPENLLSMR-DSQNISAYISLNQCFYKQFTNETFKMCG-------------------------KFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVL-FGFLSDKIGRK----VSVVILLALHMSCQMTLGFVNEVWINVVL-MSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNK 838
            P  +C++P++  +   D+ +  A     Q  ++    E    C                           +++DR Q  ET +T    VC    +  +   L +  + L  L FG+LSD+ GR+     S V+      +      F +   +  +L +SL  + V T  + + W+ + +         S  F + T +  +  L  +     +L  +++S      ++  FIPESPRWLL++ R ++ + ++   A++N 
Sbjct:   45 PHHRCRLPDSPTAAPLDNGSGPAETWGGQPPWRDDDEEGLSACSLREAAGTNASESPLRNSSEAVPCPSGWEYDRRQFTETVVTQWDLVCEHKALNHLSLTLFMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPSFSSFTAMRFLLGVSLSGIIVNTLSLSVEWLDQGHRTF---AGTSGGFAWSTGNMALGLLAYLLRGWQQLQLVVTSPIYFCILTWWFIPESPRWLLVRGRAREAHRNLSLCARING 302
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BLAST of slc22a-10 vs. Ensembl Nematostella
Match: EDO39860 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8P8])

HSP 1 Score: 60.077 bits (144), Expect = 1.114e-9
Identity = 70/293 (23.89%), Postives = 131/293 (44.71%), Query Frame = 2 
Query:  152 PRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPL-VVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGL-----IWIIEMNSCIHEPII--ISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGT--MIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDV-----SKFSLKELWRYSKIKYRLLALCFVAFSIN 985
            P F CK      S+  ++N S  +S           E    C ++ FD S++    ++    VC R+ +  +   + +  + +  V F  +SD  GR++S+ + + L  +C    G V+ V   + + +L R        G      ++ +E+    H      IS  FV   FSS  + +  I   R +LV + ++G   +I W    FIPESPRWL+ +N+  + +  +   A+ N++ + +  +   I   +  D+      K+ + +L R  K++ R   +C V +S+N
Sbjct:   52 PPFDCKG-----SLPVARNGSCGVS-----------ECCANCTEYGFDTSELTSA-VSEWQLVCSRSHLKAMTQAVYMAGLLVGSVTFSSISDHFGRRLSMFLSIFLMAAC----GIVSGVSDCLSMFALFRFGAGAACAGCLLARYVYCVELVVRKHRTAAGFISNMFVSVGFSSVTLFVYFIHEWRYQLVAVSATGLPLLIFW---WFIPESPRWLIAENKLDEAHALLTKFAEKNRVTVDSKHLMHMIREVKKADIRSDDNRKYGMLDLLRTPKLRKRTF-ICGVNWSVN 319
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BLAST of slc22a-10 vs. Ensembl Nematostella
Match: EDO32796 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU18])

HSP 1 Score: 50.0618 bits (118), Expect = 1.005e-6
Identity = 46/211 (21.80%), Postives = 103/211 (48.82%), Query Frame = 2 
Query:  404 VLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLS-VMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFL---ISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDV-----SKFSLKELWRYSKIKYRLLALCF-------VAFSINL 988
            ++F  +SD+ GR++ V I +AL   C  T GF N + + ++L  +  ++     ++  ++ +E+ S  H   +  L  +F +    ++SL+       + + L   + +  ++++  +  IPE+PRWL+ +NR  + ++ ++  A  N++ +    +   I+  +  ++      K+   +L R  K++ R L + F       V F +NL
Sbjct:   28 LVFSAVSDRFGRRIGVFISIALLAVCGTTSGFSNCLSLFILLRFVTGMANAGCLLVRYVFCMELISINHRTAVGFLTNIFVSLGFDMLSLLAYLIRDYQYLLLAVSLPAAPLVLFWGV--IPETPRWLIAQNRLDEAHKLLMDFASKNQVSVDPAHLHHVIQVVKTAELRKDMTQKYGFLDLLRTQKLRKRTLIMGFNWFVNAVVFFGLNL 236
[Close]
BLAST of slc22a-10 vs. Ensembl Nematostella
Match: EDO44960 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU66])

HSP 1 Score: 50.8322 bits (120), Expect = 1.186e-6
Identity = 89/433 (20.55%), Postives = 178/433 (41.11%), Query Frame = 2 
Query:  257 NETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIG-LIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVN--------EVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSI-LFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPT--NLVEDFIEYNEWID--VSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAV--ISSFFLAPL-WIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHR----GFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPE 1492
            N+    C  + FD   I  + +     +C R +I  ++ S+     +      G +SD  GRK ++++   L  S  +   F N        E  +   L+S    ++++E     ++IE+++     +I S+  +F      + +LI       + + L  S    ++V    +IPESPRWL+ + R  +    +      N ID      L+E   E     +    +++L +L+R  K++   L + F  F++      F++ +S L     G  ++  A+   +   L P+ W++        + V +LL+   +F  + L   P+   + +L       ++++L    + ++     + PTT R    G  S+     A+   Y S L ++  +         IY+ +  Y L  I + + F   +PE
Sbjct:  332 NKCCNNCTTYAFDGPFI--SIVNEWSLLCDRRYIAAIVQSMFFAGQLVGSSCCGMVSDAFGRKRTMLLSSGLFASFSLGASFANGYILLGFLEFMVGFFLVS----ALLSE---FTYVIELSATKRRTMIGSVVEIFWPVCLLLHTLIAFLVHEWRNLLLAVSIPGFVFVCFWRYIPESPRWLVTRGRLDEAQAVLNRFGSSNPIDQQALRGLIESIRESQIETERKAKRYTLIDLYRTPKMRKWALVMGFNWFTVQFSDMGFMLFLSVLP----GSVYVNQAIPYATQVVLIPIVWVLMQKFGRRPIHVTVLLVPGVMF--LVLMAIPE--GYPMLSAGLALTSKSILNIAWLTIYLIGSEVFPTTIRSTALGMCSTFQRCGALVAGYVSMLSQLPGL--------SIYLPVTIYGLFAIAAGVLFAIFIPE 739
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BLAST of slc22a-10 vs. Ensembl Nematostella
Match: EDO45833 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRW4])

HSP 1 Score: 48.9062 bits (115), Expect = 3.965e-6
Identity = 50/187 (26.74%), Postives = 90/187 (48.13%), Query Frame = 2 
Query:  338 VCGRNFIG-LIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWII------EMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFL--ISSGTMIIWVSILF---IPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLV 862
            +CG+  +  L  S+L I  IP   + G LSD  GR   +   +A+     ++  F   +W+ +VL +     ++    G ++I+      E     H  +  +L +VF     F +SLIT+  +   L     +S    +  + + F   +PES RW L+ NR K+  +++  IAKLN  +LP++++
Sbjct:   96 ICGKAAMASLAQSILFIGWIPGAFIIGKLSDMFGRTRMLFPSIAVVAVASLSCSFAQHLWLYLVLRA-----IIGFFEGGVYIVLYVLSTEFVGPAHRSLAGTLNWVF-----FTLSLITLDGLAYGLHDWRHLSIAVSVPALPLFFFWLVPESCRWQLVNNRCKEARQTLEHIAKLNGKNLPSDVM 272
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BLAST of slc22a-10 vs. Ensembl Medaka
Match: ENSORLT00000027238.1 (solute carrier family 22 member 5 [Source:NCBI gene;Acc:101164738])

HSP 1 Score: 68.9366 bits (167), Expect = 6.169e-12
Identity = 99/416 (23.80%), Postives = 185/416 (44.47%), Query Frame = 2 
Query:  308 RETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLF-GFLSDKIGRKVSVVILLALHMSCQMTLGFVN---EVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITT----MRS-KLVFLISSGTMIIWVSILFI-PESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSK--FSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHL-VLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQ 1516
            + T +T    VC   +     S +  + + L   F G LSD+ GRK     +L   M+ Q    F++     WI  +++    ++ + +I   +  + + + I    +  LY   GT   F V  + +      +R  K + L  S   + ++ + +I PESPRWLL + R  +    +   AK NK+  P+N+ E      E  D  K  +++ +L R+S+I+   L LCFV F++         + S+LH   Y   F+ A V    + +    ++ + +   + +I+ LI  A    + L+  P V  HL  L    + +++    T   L+F++   L PT  R  A+      +  G+  +  +  ++V ++ +     Y+I+ T   L +++ I  Y  +PE   +P P+
Sbjct:  124 QSTIVTEFDLVCTEQWKQPFTSTIFFVGVLLGSFFSGPLSDRFGRKP----VLFATMAAQTIFTFLSVFTTTWIWFIILLF--INGLGQISNFVAALVLGAEIFTGNVRVLYSSMGTCCGFAVGYMLLPLCAYFLRDWKSLLLALSVPCVAYIPLWWILPESPRWLLSQGRIAEAEAVVKMAAKWNKVQAPSNIFE--CNSVEKTDTQKEHYNVFDLLRHSRIRTTTLLLCFVLFTLITGYYCLSFNTSQLHTDPYISCFISALVEIPAYASSFIALRYFPRR--LSIIVSLIAGA----VPLYLIPLVPEHLSSLSLTLEMVSKYSFTTGASLMFAYTTELYPTVLRNTATGTTTTISRMGSCITPFLLSLSVHYKYLP----YVILAT---LAVVTAISAYF-LPESFKLPLPE 517
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BLAST of slc22a-10 vs. Ensembl Medaka
Match: ENSORLT00000001522.2 (solute carrier family 22 member 5 [Source:NCBI gene;Acc:101164738])

HSP 1 Score: 68.1662 bits (165), Expect = 9.076e-12
Identity = 99/416 (23.80%), Postives = 185/416 (44.47%), Query Frame = 2 
Query:  308 RETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLF-GFLSDKIGRKVSVVILLALHMSCQMTLGFVN---EVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITT----MRS-KLVFLISSGTMIIWVSILFI-PESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSK--FSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHL-VLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQ 1516
            + T +T    VC   +     S +  + + L   F G LSD+ GRK     +L   M+ Q    F++     WI  +++    ++ + +I   +  + + + I    +  LY   GT   F V  + +      +R  K + L  S   + ++ + +I PESPRWLL + R  +    +   AK NK+  P+N+ E      E  D  K  +++ +L R+S+I+   L LCFV F++         + S+LH   Y   F+ A V    + +    ++ + +   + +I+ LI  A    + L+  P V  HL  L    + +++    T   L+F++   L PT  R  A+      +  G+  +  +  ++V ++ +     Y+I+ T   L +++ I  Y  +PE   +P P+
Sbjct:  124 QSTIVTEFDLVCTEQWKQPFTSTIFFVGVLLGSFFSGPLSDRFGRKP----VLFATMAAQTIFTFLSVFTTTWIWFIILLF--INGLGQISNFVAALVLGAEIFTGNVRVLYSSMGTCCGFAVGYMLLPLCAYFLRDWKSLLLALSVPCVAYIPLWWILPESPRWLLSQGRIAEAEAVVKMAAKWNKVQAPSNIFE--CNSVEKTDTQKEHYNVFDLLRHSRIRTTTLLLCFVLFTLITGYYCLSFNTSQLHTDPYISCFISALVEIPAYASSFIALRYFPRR--LSIIVSLIAGA----VPLYLIPLVPEHLSSLSLTLEMVSKYSFTTGASLMFAYTTELYPTVLRNTATGTTTTISRMGSCITPFLLSLSVHYKYLP----YVILAT---LAVVTAISAYF-LPESFKLPLPE 517
[Close]
BLAST of slc22a-10 vs. Ensembl Medaka
Match: slc22a13a (solute carrier family 22 member 13 [Source:NCBI gene;Acc:101161268])

HSP 1 Score: 54.6842 bits (130), Expect = 1.659e-7
Identity = 75/307 (24.43%), Postives = 128/307 (41.69%), Query Frame = 2 
Query:  704 FLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINL--FPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVI----ILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNFNKK 1606
            F+I++   ++ V I FIPES RWLL + R  +    I  +A +NK  +  +++E  +        +K  +  L++   ++   L +    FS+NL  F  +F +       GN+G        +      P  I+ +WL  +V + +     LLI   L +SI        I+   L    +F   N   ++  L   +V  L PT+ R  AS L  +++  G   S L+ ++ V           I IV Y  L ++S    Y  +PE +    P  + +A    K +    Q E  +   N + K
Sbjct:  254 FIIATPFTVVSVYIWFIPESARWLLGRGRIDEAKLLITKVAAINKRTISDSILEKIVMKE---TETKGGIIVLFQSPVLRKYFLTIIMAWFSLNLTYFCLSFNV-------GNFGLDIFLTQAMFGLTELPAHILCIWLLEFVGRKVSIMSTLLIGGFLCFSILAVPQDNAIAVTTLAIAGRFFT-NWAGSVCSL---YVQELFPTSFRQTASGLGSIASRAGGLLSPLLNMLAVYHWS-------IPIVVYSSLTVVSGALSYL-LPETRKRELPDSTDEAEGKLKNTTSRNQPESNKPALNKSTK 538
[Close]
BLAST of slc22a-10 vs. Planmine SMEST
Match: SMESG000075938.1 (SMESG000075938.1)

HSP 1 Score: 1034.25 bits (2673), Expect = 0.000e+0
Identity = 527/532 (99.06%), Postives = 529/532 (99.44%), Query Frame = 2 
Query:   20 MYYDSIVKIFSRKKXXXXXXXXXXXXVCYVTTIHRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFNFNKKYEF 1615
            M YDSIVKIFSRKKSFLILSLFFISFVCYVTTIHRHSISIALFRPRFQC+IPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFY ICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVR+ITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDA IIEKGSEDELQREYEEKLFNFNKKYEF
Sbjct:    1 MDYDSIVKIFSRKKSFLILSLFFISFVCYVTTIHRHSISIALFRPRFQCEIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYLICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRMITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDATIIEKGSEDELQREYEEKLFNFNKKYEF 532
[Close]
BLAST of slc22a-10 vs. Planmine SMEST
Match: SMESG000025785.1 (SMESG000025785.1)

HSP 1 Score: 115.931 bits (289), Expect = 2.275e-27
Identity = 129/508 (25.39%), Postives = 225/508 (44.29%), Query Frame = 2 
Query:  125 HSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIE--YNEWIDVSKFSLKELWRYSKIKYRLLALC--FVAFSINLFPPNFVIDISKLHDGNY------GFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMIL----LFSFVINLMPTTHR----GFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDELQREYEEKLFN 1594
             ++ +++  P F C+  E       S  I   IS +QC      N +   C  + F      ET ++    VC   ++G +  LL      +  +FG+L+DK GRK+  +I L++       L F   ++ ++        S     I  +W++EM +     +  S ++++G+ +  +  L    T   +L  LIS    I++V ILF+PESPRWL +KN+ ++  ES+  IA +NK+DL     E  IE    EW   + F          + +  LA    F  FSI++     +ID++ L    Y      G      A++S            +L  Y  +   ++   ++F SI +F +  +      Q IF+ I  ++ K +++     +  +   L PTTHR    G    +L+++     Y + L      +F G      +I ++ YFLLN+IS    +  +PE K +P P+   D  ++ K    E ++EY E ++N
Sbjct:   36 QNLLVSIRTPNFTCQYNET------SHQIQ--ISKDQC--TMTINGSNVKCQHWTFSSEPFGETIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLYSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKEWNKWNAF--------KDMNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLS------------YLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVMTSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKL-----NQFYG------FIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVK----EREQEYLEYMYN 498
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BLAST of slc22a-10 vs. Planmine SMEST
Match: SMESG000025822.1 (SMESG000025822.1)

HSP 1 Score: 102.449 bits (254), Expect = 6.485e-23
Identity = 125/508 (24.61%), Postives = 213/508 (41.93%), Query Frame = 2 
Query:  119 HRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFI-----EYNEW--IDVSKFSLKELWRYSKIKYRLLALCF-VAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHR--GFASSLLV-----VSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDEL------QREYE 1579
               +I I+ + P++ C        + +S      IS +QC      + +  +C K+ F    +  T ++    VC    +G I  ++         + G+ SDK GRK   +  L L       + F  +V  N++   L  +S        +W++EM          S  + +G  +  +  L    T   ++  LIS    I++  IL  PESPRWL + NR  +  +S+  IA++NKID   N  + F+     E+N W  +    FSL+            + L F + FSINL      +++  L +  Y   FL   +     L     ++ + +      I++    ++F  I +FF+  ++   V++ IF  IA+  + T       +V  L PT+HR  GFAS  L       +AI+ N  S      TV F        ++ +V YF+L  ++    Y  +PE K +P P+   D  +++   E E       +RE E
Sbjct:   34 QMQNILISTYTPKYTC--------LYNSSFSKISISADQC--NMIIDGSTIVCNKWNFSYEPVGRTMMSDFSLVCNYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLR------------MTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILFSYVSLRFFRRK--TSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAIYINKLS------TVLF--------FLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREME 503
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BLAST of slc22a-10 vs. Planmine SMEST
Match: SMESG000025819.1 (SMESG000025819.1)

HSP 1 Score: 100.908 bits (250), Expect = 2.430e-22
Identity = 125/508 (24.61%), Postives = 213/508 (41.93%), Query Frame = 2 
Query:  119 HRHSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFI-----EYNEW--IDVSKFSLKELWRYSKIKYRLLALCF-VAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHR--GFASSLLV-----VSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKCIPYPQISSDAAIIEKGSEDEL------QREYE 1579
               +I I+ + P++ C        + +S      IS +QC      + +  +C K+ F    +  T ++    VC    +G I  ++         + G+ SDK GRK   +  L L       + F  +V  N++   L  +S        +W++EM          S  + +G  +  +  L    T   ++  LIS    I++  IL  PESPRWL + NR  +  +S+  IA++NKID   N  + F+     E+N W  +    FSL+            + L F + FSINL      +++  L +  Y   FL   +     L     ++ + +      I++    ++F  I +FF+  ++   V++ IF  IA+  + T       +V  L PT+HR  GFAS  L       +AI+ N  S      TV F        ++ +V YF+L  ++    Y  +PE K +P P+   D  +++   E E       +RE E
Sbjct:   34 QMQNILISTYTPKYTC--------LYNSSFSKISISADQC--NMIIDGSTIVCNKWNFLYEPVGRTMMSDFSLVCDYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLR------------MTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILFSYVSLRFFRRK--TSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAIYINKLS------TVLF--------FLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREME 503
[Close]
BLAST of slc22a-10 vs. Planmine SMEST
Match: SMESG000025834.1 (SMESG000025834.1)

HSP 1 Score: 95.5153 bits (236), Expect = 9.575e-21
Identity = 124/503 (24.65%), Postives = 210/503 (41.75%), Query Frame = 2 
Query:  125 HSISIALFRPRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRSQIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSVVILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSCIHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSG------TMIIWVSILFIPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVSKFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAFLKAAVISSFFLAPLWIIKLWLKTYVMQVI-----ILLI--TAALFYSICLFFNP----QVISHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIFGNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISY-------ICFYHQVPEIKCIPYPQISSDAAIIEKGSEDE 1561
             +I  ALF P F+CK          +      +S +QC      N T   C ++ F    I  T ++    VC   ++G +  ++      L  L GF+SD+ GRK                         N+V++SL              ++E  S     I+++L   F T+ +F + L     + S  +   S G      T + ++ I F+PESPRWL + NR  +  ES+  ++K+N++       + ++E      V + ++    + +  + R +   F AFSINL   + ++DI  L    Y         +S F L  + +  L L  YV++ I      LLI    +L   I +FF+     Q +  +VL  + K    +  + IM+    +V  L PTTHR F  +LL++S      FS  V I  +             +++YFL  +I +       +  Y  +PE K +P P+   D  +++ G E+E
Sbjct:   36 QNILFALFIPNFKCKF---------NSKSKFIVSKDQC--SILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPLVGFMSDRFGRK-------------------------NIVILSL--------------VLETFS----SILLALSPNFATYLTFRILLGLSAILSSGRLLDRSIGSIGQSLTCVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVEN----LVKEGNICVACKDTDFQSRSITALFCAFSINLIYSSMLVDIGILSSNMY---------LSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMV----YVNELFPTTHRSFGITLLLISNFLS--FSGAVLINRLS------------VISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEE 453
The following BLAST results are available for this feature:
BLAST of slc22a-10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SLC22A244.370e-720.59solute carrier family 22 member 24 [Source:HGNC Sy... [more]
SLC22A246.395e-722.79solute carrier family 22 member 24 [Source:HGNC Sy... [more]
SLC22A159.286e-627.50solute carrier family 22 member 15 [Source:HGNC Sy... [more]
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BLAST of slc22a-10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
oct-22.508e-1324.18Organic Cation Transporter [Source:UniProtKB/TrEM... [more]
K05F1.66.440e-1322.10pep chromosome:WBcel235:II:5782942:5787658:1 gene:... [more]
K05F1.66.440e-1322.10pep chromosome:WBcel235:II:5782524:5787658:1 gene:... [more]
K05F1.66.447e-1322.10pep chromosome:WBcel235:II:5782942:5787658:1 gene:... [more]
K05F1.66.447e-1322.10pep chromosome:WBcel235:II:5782524:5787658:1 gene:... [more]
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BLAST of slc22a-10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Orct1.629e-1025.09gene:FBgn0019952 transcript:FBtr0334870[more]
Orct1.629e-1025.09gene:FBgn0019952 transcript:FBtr0084599[more]
Orct21.718e-1025.17gene:FBgn0086365 transcript:FBtr0084598[more]
Orct21.718e-1025.17gene:FBgn0086365 transcript:FBtr0334869[more]
CG177516.208e-926.55gene:FBgn0038717 transcript:FBtr0273217[more]
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BLAST of slc22a-10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc22a215.116e-730.51solute carrier family 22 member 21 [Source:ZFIN;Ac... [more]
slc22a215.342e-731.13solute carrier family 22 member 21 [Source:ZFIN;Ac... [more]
si:dkey-166k12.11.453e-621.68si:dkey-166k12.1 [Source:ZFIN;Acc:ZDB-GENE-120215-... [more]
si:dkey-166k12.11.708e-621.68si:dkey-166k12.1 [Source:ZFIN;Acc:ZDB-GENE-120215-... [more]
slc22a162.876e-620.33solute carrier family 22 member 16 [Source:ZFIN;Ac... [more]
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BLAST of slc22a-10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc22a-10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Slc22a72.933e-822.15solute carrier family 22 (organic anion transporte... [more]
Slc22a154.613e-627.50solute carrier family 22 (organic anion/cation tra... [more]
Slc22a79.281e-621.80solute carrier family 22 (organic anion transporte... [more]
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BLAST of slc22a-10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9VCA2|ORCT_DROME1.633e-925.09Organic cation transporter protein OS=Drosophila m... [more]
sp|Q95R48|OCTL_DROME1.722e-925.17Organic cation transporter-like protein OS=Drosoph... [more]
sp|Q91WU2|S22A7_MOUSE2.088e-722.15Solute carrier family 22 member 7 OS=Mus musculus ... [more]
sp|Q5RLM2|S22A7_RAT2.938e-723.02Solute carrier family 22 member 7 OS=Rattus norveg... [more]
sp|Q8N4F4|S22AO_HUMAN2.099e-620.59Steroid transmembrane transporter SLC22A24 OS=Homo... [more]
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BLAST of slc22a-10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YK970.000e+099.44Slc22a-10 OS=Schmidtea mediterranea OX=79327 GN=sl... [more]
A0A0H3YFD14.297e-2525.29Slc22a-9 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
A0A0H3YF344.410e-2225.34Slc22a-7 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
A0A0H3YJ933.350e-1924.80Slc22a-1 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
A0A0H3YF328.450e-1623.49Slc22a-2 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
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BLAST of slc22a-10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
si:dkey-166k12.12.581e-723.66organic cation transporter protein-like [Source:NC... [more]
si:dkey-166k12.13.629e-723.51organic cation transporter protein-like [Source:NC... [more]
SLC22A24.110e-725.85solute carrier family 22 member 2-like [Source:NCB... [more]
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BLAST of slc22a-10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
oct21.735e-821.13organic cation transporter 2 [Source:ZFIN;Acc:ZDB-... [more]
SLC22A71.378e-620.69solute carrier family 22 member 7 [Source:HGNC Sym... [more]
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BLAST of slc22a-10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc22a-10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO398601.114e-923.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO327961.005e-621.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449601.186e-620.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458333.965e-626.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of slc22a-10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSORLT00000027238.16.169e-1223.80solute carrier family 22 member 5 [Source:NCBI gen... [more]
ENSORLT00000001522.29.076e-1223.80solute carrier family 22 member 5 [Source:NCBI gen... [more]
slc22a13a1.659e-724.43solute carrier family 22 member 13 [Source:NCBI ge... [more]
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BLAST of slc22a-10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000075938.10.000e+099.06SMESG000075938.1[more]
SMESG000025785.12.275e-2725.39SMESG000025785.1[more]
SMESG000025822.16.485e-2324.61SMESG000025822.1[more]
SMESG000025819.12.430e-2224.61SMESG000025819.1[more]
SMESG000025834.19.575e-2124.65SMESG000025834.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30016659
GenBankAKN21558.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016659 ID=SMED30016659|Name=slc22a-10|organism=Schmidtea mediterranea sexual|type=transcript|length=1617bp
TATTTACAGTTGTAAACAAATGTACTACGATTCAATTGTTAAGATTTTTA
GTAGAAAGAAATCGTTTTTGATTCTTTCTTTATTTTTCATTTCTTTCGTG
TGTTACGTAACAACTATTCATCGTCATTCCATTTCAATCGCTTTATTTCG
ACCGAGATTTCAGTGCAAAATTCCTGAAAACTTGCTGTCCATGAGAGACT
CCCAGAATATTTCCGCCTATATTTCATTAAATCAATGTTTTTACAAGCAA
TTTACCAATGAAACTTTTAAAATGTGCGGCAAGTTTAAATTTGATCGAAG
TCAAATACGAGAAACATTTATCACAACAAATCATGCCGTTTGCGGTAGGA
ATTTCATTGGATTGATTTACAGTTTGCTACAGATAATCAACATCCCATTG
GTTGTTCTATTTGGATTTCTCTCGGATAAAATTGGTAGAAAGGTTTCTGT
GGTAATATTATTAGCGCTGCATATGTCATGCCAAATGACTCTTGGATTTG
TTAATGAAGTATGGATCAATGTTGTTTTGATGTCTCTGAAACGGTTATCA
GTAATGACAGAAATAATCGGTCTTATCTGGATCATTGAAATGAACTCATG
CATTCATGAACCGATAATAATCAGCTTGTATTTTGTGTTCGGAACATTTT
CTTCTTTCATCGTTTCTTTAATAACTATTACAACAATGCGTTCGAAATTG
GTTTTCCTCATTTCATCTGGAACTATGATTATTTGGGTTTCGATTCTGTT
TATTCCTGAATCACCAAGATGGCTTTTGATAAAGAATCGACACAAAAAAT
TCTACGAATCAATAATAGCAATTGCAAAACTTAACAAAATCGATTTGCCG
ACAAATCTTGTGGAAGACTTTATTGAATACAACGAATGGATAGATGTATC
GAAATTTTCTCTGAAAGAATTATGGAGATATTCAAAAATAAAATATCGAC
TATTGGCACTTTGTTTTGTGGCATTTTCAATCAATCTTTTCCCGCCGAAT
TTCGTAATAGATATCAGCAAATTACATGATGGCAATTACGGGTTTGCGTT
TCTTAAAGCTGCAGTCATTTCTTCGTTCTTTCTTGCTCCTTTATGGATAA
TTAAATTGTGGCTCAAAACATACGTTATGCAGGTGATAATCCTGCTTATT
ACCGCTGCGTTGTTTTACTCGATCTGTCTATTTTTCAACCCACAAGTTAT
CAGTCATCTAGTTTTGCAGTATATTTTCAAATTTATCGCCCAAAACCTCC
TAAAAACAATAATGATTTTGTTATTTAGTTTTGTGATTAATTTAATGCCA
ACGACTCATCGTGGTTTCGCTTCTTCTTTGCTAGTAGTCTCTGCTATTTT
CGGTAATTATTTCTCGAACTTAGTTAGAATTATCACAGTCAAGTTTCGAG
GAATGATGCGAGACGATATTTACATAATTATTGTAACATATTTTTTGTTA
AACATTATTAGCTATATTTGCTTCTATCACCAAGTCCCAGAAATCAAATG
TATTCCGTATCCTCAAATTTCTAGTGATGCCGCAATAATTGAAAAAGGAA
GTGAAGATGAATTACAGCGTGAATATGAAGAAAAGCTCTTTAACTTTAAT
AAAAAATATGAATTTAC
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protein sequence of SMED30016659-orf-1

>SMED30016659-orf-1 ID=SMED30016659-orf-1|Name=SMED30016659-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=538bp
IYSCKQMYYDSIVKIFSRKKSFLILSLFFISFVCYVTTIHRHSISIALFR
PRFQCKIPENLLSMRDSQNISAYISLNQCFYKQFTNETFKMCGKFKFDRS
QIRETFITTNHAVCGRNFIGLIYSLLQIINIPLVVLFGFLSDKIGRKVSV
VILLALHMSCQMTLGFVNEVWINVVLMSLKRLSVMTEIIGLIWIIEMNSC
IHEPIIISLYFVFGTFSSFIVSLITITTMRSKLVFLISSGTMIIWVSILF
IPESPRWLLIKNRHKKFYESIIAIAKLNKIDLPTNLVEDFIEYNEWIDVS
KFSLKELWRYSKIKYRLLALCFVAFSINLFPPNFVIDISKLHDGNYGFAF
LKAAVISSFFLAPLWIIKLWLKTYVMQVIILLITAALFYSICLFFNPQVI
SHLVLQYIFKFIAQNLLKTIMILLFSFVINLMPTTHRGFASSLLVVSAIF
GNYFSNLVRIITVKFRGMMRDDIYIIIVTYFLLNIISYICFYHQVPEIKC
IPYPQISSDAAIIEKGSEDELQREYEEKLFNFNKKYEF
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000035Category 3 cell
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR036259MFS_trans_sf
IPR005828MFS_sugar_transport-like
IPR020846MFS_dom
Vocabulary: molecular function
TermDefinition
GO:0022857transmembrane transporter activity
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.20.1250.20coord: 60..508
e-value: 5.1E-25
score: 90.1
NoneNo IPR availablePANTHERPTHR24064:SF524ORGANIC CATION/CARNITINE TRANSPORTER 4coord: 35..500
NoneNo IPR availablePANTHERPTHR24064FAMILY NOT NAMEDcoord: 35..500
NoneNo IPR availableCDDcd06174MFScoord: 119..488
e-value: 1.14327E-4
score: 42.4138
NoneNo IPR availableTMHMMTMhelixcoord: 439..461
NoneNo IPR availableTMHMMTMhelixcoord: 233..252
NoneNo IPR availableTMHMMTMhelixcoord: 407..429
NoneNo IPR availableTMHMMTMhelixcoord: 118..140
NoneNo IPR availableTMHMMTMhelixcoord: 21..39
NoneNo IPR availableTMHMMTMhelixcoord: 473..495
NoneNo IPR availableTMHMMTMhelixcoord: 317..336
NoneNo IPR availableTMHMMTMhelixcoord: 204..226
NoneNo IPR availableTMHMMTMhelixcoord: 373..395
NoneNo IPR availableTMHMMTMhelixcoord: 348..367
NoneNo IPR availableTMHMMTMhelixcoord: 153..175
IPR005828Major facilitator, sugar transporter-likePFAMPF00083Sugar_trcoord: 68..504
e-value: 9.4E-9
score: 34.6
IPR036259MFS transporter superfamilySUPERFAMILYSSF103473MFS general substrate transportercoord: 117..494