Fe2OG dioxygenase domain-containing protein

Overview
NameFe2OG dioxygenase domain-containing protein
Smed IDSMED30016646
Length (bp)1896
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Fe2OG dioxygenase domain-containing protein (SMED30016646) t-SNE clustered cells

Violin plots show distribution of expression levels for Fe2OG dioxygenase domain-containing protein (SMED30016646) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Fe2OG dioxygenase domain-containing protein (SMED30016646) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Fe2OG dioxygenase domain-containing protein (SMED30016646) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30016646

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30016646SMESG000006029.1 SmedASXL_013459SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30016646SMESG000006029.1 SmedASXL_013459SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
cephalic gangliaSMED30016646SMESG000006029.1 SMESG000007955.1 dd_Smed_v4_2627_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30016646SMESG000006029.1 SMESG000007955.1 dd_Smed_v4_2627_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30016646SMESG000006029.1 SMESG000007955.1 dd_Smed_v4_2627_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016646SMESG000006029.1 Contig37500newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016646SMESG000006029.1 Contig37500uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
prepharyngeal regionSMED30016646SMESG000006029.1 SMESG000007955.1 dd_Smed_v6_2627_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30016646SMESG000006029.1 OX_Smed_1.0.10533ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 113.62 bits (283), Expect = 7.755e-26
Identity = 115/482 (23.86%), Postives = 205/482 (42.53%), Query Frame = 3 
Query:  444 HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFES--EIKNNDNQF---------------RNLVRMKAAALFNTKNEKEAINL--LEEII---REKLFDNK----------LLERDLKFYKSKSEQDKV-NAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            HP+NA   ++R        LN   T    L+    QD ++     +  +   +PT  D   A   + R+ + Y++    IS+G +   T    ML +D+   + + + N  +Y+  VL W E +L   ++  E     +Q                R L   +     +  +E+   NL   E+++   REK   N+          + ER + +   +   + +   E   +       L CR ++ +     L   ++  +  WD         +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+  +  +   K      G+RLAT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:   82 HPVNAYKLVKR--------LN---TDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPG-TKYQAMLSVDDCFGMGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKE-EDEWD---------SPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGVGGQYEPHFDFSRRPFDSGLKTE----GNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 527
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 113.62 bits (283), Expect = 7.755e-26
Identity = 115/482 (23.86%), Postives = 205/482 (42.53%), Query Frame = 3 
Query:  444 HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFES--EIKNNDNQF---------------RNLVRMKAAALFNTKNEKEAINL--LEEII---REKLFDNK----------LLERDLKFYKSKSEQDKV-NAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            HP+NA   ++R        LN   T    L+    QD ++     +  +   +PT  D   A   + R+ + Y++    IS+G +   T    ML +D+   + + + N  +Y+  VL W E +L   ++  E     +Q                R L   +     +  +E+   NL   E+++   REK   N+          + ER + +   +   + +   E   +       L CR ++ +     L   ++  +  WD         +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+  +  +   K      G+RLAT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:   82 HPVNAYKLVKR--------LN---TDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPG-TKYQAMLSVDDCFGMGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKE-EDEWD---------SPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGVGGQYEPHFDFSRRPFDSGLKTE----GNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 527
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 113.62 bits (283), Expect = 7.755e-26
Identity = 115/482 (23.86%), Postives = 205/482 (42.53%), Query Frame = 3 
Query:  444 HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFES--EIKNNDNQF---------------RNLVRMKAAALFNTKNEKEAINL--LEEII---REKLFDNK----------LLERDLKFYKSKSEQDKV-NAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            HP+NA   ++R        LN   T    L+    QD ++     +  +   +PT  D   A   + R+ + Y++    IS+G +   T    ML +D+   + + + N  +Y+  VL W E +L   ++  E     +Q                R L   +     +  +E+   NL   E+++   REK   N+          + ER + +   +   + +   E   +       L CR ++ +     L   ++  +  WD         +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+  +  +   K      G+RLAT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:   82 HPVNAYKLVKR--------LN---TDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPG-TKYQAMLSVDDCFGMGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKE-EDEWD---------SPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGVGGQYEPHFDFSRRPFDSGLKTE----GNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 527
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 112.849 bits (281), Expect = 1.237e-25
Identity = 114/482 (23.65%), Postives = 207/482 (42.95%), Query Frame = 3 
Query:  444 HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFES--EIKNNDNQF---------------RNLVRMKAAALFNTKNEKEAINL--LEEII---REKLFDNK----------LLERDLKFYKSKSEQDKV-NAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            HP+NA   ++R        LN   T    L+    QD ++     +  +   +PT  D   A   + R+ + Y++    IS+G +   T    ML +D+   + + + N  +Y+  VL W E +L   ++  E     +Q                R L   +     +  +E+   NL   E+++   REK   N+          + ER + +   +   + +   E   +       L CR ++ +     L   ++  +  WD         +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+    ++E+     +  G+R+AT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:   82 HPVNAYKLVKR--------LN---TDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPG-TKYQAMLSVDDCFGMGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKE-EDEWD---------SPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGVGGQYEPHFDF--SRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 112.849 bits (281), Expect = 1.237e-25
Identity = 114/482 (23.65%), Postives = 207/482 (42.95%), Query Frame = 3 
Query:  444 HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFES--EIKNNDNQF---------------RNLVRMKAAALFNTKNEKEAINL--LEEII---REKLFDNK----------LLERDLKFYKSKSEQDKV-NAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            HP+NA   ++R        LN   T    L+    QD ++     +  +   +PT  D   A   + R+ + Y++    IS+G +   T    ML +D+   + + + N  +Y+  VL W E +L   ++  E     +Q                R L   +     +  +E+   NL   E+++   REK   N+          + ER + +   +   + +   E   +       L CR ++ +     L   ++  +  WD         +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+    ++E+     +  G+R+AT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:   82 HPVNAYKLVKR--------LN---TDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPG-TKYQAMLSVDDCFGMGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKE-EDEWD---------SPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGVGGQYEPHFDF--SRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Match: dpy-18 (Prolyl 4-hydroxylase subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q10576])

HSP 1 Score: 130.954 bits (328), Expect = 5.186e-32
Identity = 126/502 (25.10%), Postives = 231/502 (46.02%), Query Frame = 3 
Query:  417 ESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRY--IREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLS-----------NNSD-----LLCRENYNSSE--YYNLRCFYRRIKK--GWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKT--SKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRKTASFF*KDSFQNEFCSNLG 1847
            E+  K  TN PINA   ++R +F    I +++  +K          +SS+ D    +R     +PT  DL  A  G+ R+ + Y++   +++ G I+           +   +A+ + N  +++  V+ W E        E++    +  +++   A AL+   N K A+ L EE+ +      +  + ++K+Y+   EQ+ V   +   NL             N++      LCR     S+     L C+Y+R +    +   KVE+   NP    +  V++D+++  +  L K   ++   H  +   ++ A  + +K  A   + + DV+++++++I + T LE         + ++   ++ NYGIGG+ +   D+     EE K   S+  G+R+AT  ++++    GG  VF + K ++L  +   L W+NL K G  NP + H  CPV  G KWV  K+IHE GN F R C  K++ +         F  +LG
Sbjct:   69 ENGLKDITN-PINAFLLIKRKIFDWKEIESKMNANKA------GNVVSSITDDSYGVR-----YPTADDLSGAAIGLLRLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVM-WMEEAQRRLGDEVEPT-VEVEDILEYLAFALYKQNNLKHALKLTEELYKMNPTHPRA-KGNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEVPVSQKDISRLYCYYKRDRPFLVYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKS-AWLKEWEGDVVETVNKRIGYMTNLE---------METAEELQIANYGIGGHYDPHFDH--AKKEESKSFESLGTGNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRPCGLKSSDY-------ERFVGDLG 536
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Match: phy-2 (Prolyl 4-hydroxylase subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:Q20065])

HSP 1 Score: 109.768 bits (273), Expect = 4.425e-25
Identity = 128/525 (24.38%), Postives = 224/525 (42.67%), Query Frame = 3 
Query:  285 VKAILNGYKTLEEDRYD--KRNAKDYTELDGEIRKTLEILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIR---------------EKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYY---NLRCFYRRIKKGWDRA--KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYL--EKGVL-NANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            V  I++ Y   E  R D  +R A +Y   +                ES       +PINA   ++R+      + N +  +K      F   L ++ D  +R E   +P   DL  A + + R+ + Y +   ++S GII      N +   +   + + + N+K+Y+   L W +  L   E+E      ++  ++   A +L+   N + A++L + + +               E +   K +  DL    +K        E   I   +  + LCR      E      LRC+ +R K     A  KVE+L  +P    +  V++D +I EV   + + K+K+      + G L +A  + +K   +  D D  V+  ++R+I   T L           ++S   +V NYG+GG+ +   D+     EEK    ++  G+R+AT  ++++    GG  VF  +  ++   +   L W+NL ++G  +  + H  CPV  G KWV  K+IHE G  FTR C
Sbjct:   35 VTTIIDQYIEAERARLDDLRRYAHEYVHRNAH-------------AESVGPEFVTNPINAYLLIKRLTTEWKKVENIMLNNKA---STF---LKNITDNRVRSEVK-FPGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYH-CLMWMQVALVKIENENPPTIEEWE-ILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDMLQGKDMVGDLPPIVNK------RVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEI-EVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDLD-PVIDRVNRRIEDFTNLNQ---------ATSEELQVANYGLGGHYDPHFDF--ARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPC 518
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Match: phy-4 (Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:B1V8J4])

HSP 1 Score: 61.2326 bits (147), Expect = 5.044e-10
Identity = 36/134 (26.87%), Postives = 66/134 (49.25%), Query Frame = 3 
Query: 1380 GLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            GL+ N +  +  +S++ P+++++Y   GY     DYL      +  +     G+R+AT    L    +GG  VFP++ +++  + G  ++W N L  G  N  + H  CP+  G+K     ++HE    F+  C
Sbjct:  136 GLQANINSLD--LSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEGR---GNRIATVLVILQIAKKGGTTVFPRLNLNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIGATLWVHEKKQEFSLPC 264
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Match: phy-4 (Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:B1V8J4])

HSP 1 Score: 56.9954 bits (136), Expect = 1.337e-8
Identity = 34/125 (27.20%), Postives = 63/125 (50.40%), Query Frame = 3 
Query: 1380 GLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHE 1754
            GL+ N +  +  +S++ P+++++Y   GY     DYL      +  +     G+R+AT    L    +GG  VFP++ +++  + G  ++W N L  G  N  + H  CP+  G+K     ++HE
Sbjct:  136 GLQANINSLD--LSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEGR---GNRIATVLVILQIAKKGGTTVFPRLNLNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIGATLWVHE 255
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Match: Y43F8B.19 (pep chromosome:WBcel235:V:19510780:19512164:-1 gene:WBGene00077688.1 transcript:Y43F8B.19.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43F8B.19)

HSP 1 Score: 50.0618 bits (118), Expect = 1.460e-6
Identity = 28/96 (29.17%), Postives = 42/96 (43.75%), Query Frame = 3 
Query: 1440 VINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSK 1727
             ++Y  GG+     DYL    E++  +     G+R  T          GG  VFP++  ++  + G    WFN + N     LSEH  CP+  G K
Sbjct:  114 ALSYNPGGHYAAHHDYLLYPSEKEWDEWMRVNGNRFGTLIMAFGAAESGGATVFPRLGAAVRTKPGDAFFWFNAMGNSEQEDLSEHAGCPIYKGQK 209
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Match: CG31013 (gene:FBgn0051013 transcript:FBtr0085671)

HSP 1 Score: 147.902 bits (372), Expect = 9.465e-38
Identity = 110/412 (26.70%), Postives = 186/412 (45.15%), Query Frame = 3 
Query:  603 PTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFR----NLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLL---ERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRA---KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFW--DEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFG---GDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRKT 1793
            PT  DL  A  GIARI + Y +   +   G I      + M   +++ +      KN  SD ++W + +    + E+            + +R+ A A    +N  EA+ LL   ++ +  D ++L   ++   F +++ +Q     + +N+ ++N   L C     SS    L CFY      + R    K E + ++P +  Y+ VL+  +I  +      +     ++ E+ V   N    +    FW   E  ++ K ++R+I   TG +         ++ S  F+VINYGIGG+  L +DY            S +    GDR+AT  ++LTD  +GG  VF  V   +  + GT + W+NL  +G  +P + H  CPV  GSKWV+ ++I E   +F R C  K 
Sbjct:  129 PTERDLWDACEGIARIQSTYDLKVGDFINGNINGKQYNDSMSTADILSVGAYLFMKNRPSDAIQWLQEVPQRLQEELLIQPRHLPIKEVDALRLLAEAQIKDQNYSEALPLLHNCLKLQPHDARVLRLWKKTTDFIENQPDQSPTENKKRNVPIANAFKLSCNGPLESST--RLHCFYNFTTTPFLRLAPLKTEQIGLDPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKERAVPKKNR--GRTAKGFWLKKESNELTKRITRRIMDMTGFD---------LADSEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSRYSIDLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNGDPRTRHAACPVIVGSKWVMTEWIREKRQIFIRPCLPKA 527
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Match: PH4alphaPV (gene:FBgn0051015 transcript:FBtr0085670)

HSP 1 Score: 128.257 bits (321), Expect = 4.686e-31
Identity = 128/546 (23.44%), Postives = 238/546 (43.59%), Query Frame = 3 
Query:  228 HCSVSASGLRDSYFVEGQLVKAILNGYKTLEEDRYDKRNAKDYT-ELDGEIRKTLEILTAAR----RTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRY--IREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGI-----------IFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMK-AAALFNTKNEKEAINLLEEIIREKLFDNKLL--ERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGW---DRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMK-SLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRK 1790
            HC+ S +G+     +E QL+                  N +DY  EL+ +++     +T+ R    +  S+T+   ++P+N+   +RR        +NR +     +    Y D    + +   I+E     PT +D++ AV+ + RI + Y +    IS G            + +  ++  +L D+   LA  S    Y S VL  A  +    E          +N VRM  A  L       +A+ ++   + +   D KLL  + +++        +    + Q   +     + CR  +  S    L C Y R    +      K+EL+ ++P +  Y+ VL+ ++I E+  +      +  VY      N   K    +  ++ + Y+ +   L+ +IS  TG           +  S   +++NYG+GG+ +   D+      +   +++   GDR+AT  ++LTD  +GG  VFP ++ ++  ++G+ ++W+NL  NG ++  + H  CPV  GSKWV  K+I E   +F+R C +K
Sbjct:   32 HCT-SVAGMVKLLDLEAQLID-----------------NLEDYAVELEKKLQTVRRSITSLRLENDKARSSTEEYLSNPLNSFSLIRR--------MNRDW-----IIWQLYMDDPVGISQVERIQELREHMPTHTDVEEAVTALDRIQSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAAS--WIYQSVVLMEAFSMAAPLEIS--------KNEVRMVYAETLLKLNQHADALKVVNIALTDNPHDIKLLLKKSEIETMIRTGTNNAPPVKVQATGVPTAYQIGCRGQFPPSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFN---------LYGSEMLQLMNYGLGGHYDQHYDFF----NKTNSNMTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPCLKK 523
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Match: CG15539 (gene:FBgn0039782 transcript:FBtr0085655)

HSP 1 Score: 117.857 bits (294), Expect = 2.370e-28
Identity = 105/404 (25.99%), Postives = 190/404 (47.03%), Query Frame = 3 
Query:  603 PTPSDLQVAVSGIARIINVYKIPKANISKGI---IFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFES--EIKNNDNQFRNLVRMKAAALFNTKNE--KEAINLLEEIIREKLFDNKL-LERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRA---KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            PT  D++ A+ G+  I   Y +P A ++KG+   I ++TS++ M   + I +A+            EW    L  +E+  EI+   +Q    +          ++E     + + E  +  K +  K+ L+R L   K      K  AE +N +          E   +++ Y   C Y+     + R    K+ELL+++P +  ++ V++D+DI  + NL K  K+ + V + K      +     +  +  E+  +++ LS+     T         N  I  + PF+V+NYGIGG+  +  D+L   + +          DR+AT  ++L+D  +GG  +FPK+ +S+  ++G+ LLW+NL   G  +  + H  CP   GS+WV+ K+I+E   +F R C
Sbjct:    2 PTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVLQDIHHNTSLDGM---QCITIARHMVNYKDFIRAKEWLMVGLKMYEADEEIEYIYSQLGMPLVDFYELFVEIQDELGSRYLAMSELQLAIKNWPEKVSLQRALSRLKMNIRIGKEPAEKKNKSKRVYKKCCSSECRPTAKLY---CLYKTTSSYFLRLAPLKMELLSLDPYMVLFHDVVSDKDIVSIRNLTK-GKLARTVTVSKDGNYTEDPDRTTKGTWLVENNALIQRLSQLTQDMT---------NFDIHDADPFQVLNYGIGGFYGIHFDFLEDAELDNF-------SDRIATAVFYLSDVPQGGATIFPKLGLSVFPKKGSALLWYNLDHKGDGDNRTAHSACPTVVGSRWVMTKWINEREQIFRRPC 382
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Match: CG15539 (gene:FBgn0039782 transcript:FBtr0345121)

HSP 1 Score: 117.472 bits (293), Expect = 1.292e-27
Identity = 104/420 (24.76%), Postives = 188/420 (44.76%), Query Frame = 3 
Query:  603 PTPSDLQVAVSGIARIINVYKIPKANISKGI---IFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESE---------------------IKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRA---KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            PT  D++ A+ G+  I   Y +P A ++KG+   I ++TS++ M   + I +A+            EW    L  +E++                     ++  D      + M    L   KN  E ++L   + R K+        +++  K  +E++K     +    S      CR          L C Y+     + R    K+ELL+++P +  ++ V++D+DI  + NL K  K+ + V + K      +     +  +  E+  +++ LS+     T         N  I  + PF+V+NYGIGG+  +  D+L   + +          DR+AT  ++L+D  +GG  +FPK+ +S+  ++G+ LLW+NL   G  +  + H  CP   GS+WV+ K+I+E   +F R C
Sbjct:  125 PTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVLQDIHHNTSLDGM---QCITIARHMVNYKDFIRAKEWLMVGLKMYEADEEIEYIYSQLGMPLVDFYELFVEIQDELGSRYLAMSELQL-AIKNWPEKVSLQRALSRLKM--------NIRIGKEPAEKNKSKRVYKKCCSSE-----CRPTAK------LYCLYKTTSSYFLRLAPLKMELLSLDPYMVLFHDVVSDKDIVSIRNLTK-GKLARTVTVSKDGNYTEDPDRTTKGTWLVENNALIQRLSQLTQDMT---------NFDIHDADPFQVLNYGIGGFYGIHFDFLEDAELDNF-------SDRIATAVFYLSDVPQGGATIFPKLGLSVFPKKGSALLWYNLDHKGDGDNRTAHSACPTVVGSRWVMTKWINEREQIFRRPC 504
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Match: CG15539 (gene:FBgn0039782 transcript:FBtr0110859)

HSP 1 Score: 117.472 bits (293), Expect = 1.340e-27
Identity = 105/404 (25.99%), Postives = 190/404 (47.03%), Query Frame = 3 
Query:  603 PTPSDLQVAVSGIARIINVYKIPKANISKGI---IFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFES--EIKNNDNQFRNLVRMKAAALFNTKNE--KEAINLLEEIIREKLFDNKL-LERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRA---KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            PT  D++ A+ G+  I   Y +P A ++KG+   I ++TS++ M   + I +A+            EW    L  +E+  EI+   +Q    +          ++E     + + E  +  K +  K+ L+R L   K      K  AE +N +          E   +++ Y   C Y+     + R    K+ELL+++P +  ++ V++D+DI  + NL K  K+ + V + K      +     +  +  E+  +++ LS+     T         N  I  + PF+V+NYGIGG+  +  D+L   + +          DR+AT  ++L+D  +GG  +FPK+ +S+  ++G+ LLW+NL   G  +  + H  CP   GS+WV+ K+I+E   +F R C
Sbjct:  125 PTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVLQDIHHNTSLDGM---QCITIARHMVNYKDFIRAKEWLMVGLKMYEADEEIEYIYSQLGMPLVDFYELFVEIQDELGSRYLAMSELQLAIKNWPEKVSLQRALSRLKMNIRIGKEPAEKKNKSKRVYKKCCSSECRPTAKLY---CLYKTTSSYFLRLAPLKMELLSLDPYMVLFHDVVSDKDIVSIRNLTK-GKLARTVTVSKDGNYTEDPDRTTKGTWLVENNALIQRLSQLTQDMT---------NFDIHDADPFQVLNYGIGGFYGIHFDFLEDAELDNF-------SDRIATAVFYLSDVPQGGATIFPKLGLSVFPKKGSALLWYNLDHKGDGDNRTAHSACPTVVGSRWVMTKWINEREQIFRRPC 505
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: p4ha1b (prolyl 4-hydroxylase, alpha polypeptide I b [Source:ZFIN;Acc:ZDB-GENE-030131-4089])

HSP 1 Score: 108.227 bits (269), Expect = 2.987e-24
Identity = 113/502 (22.51%), Postives = 209/502 (41.63%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQ--ESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIRE-----------KLFDNKLLERDLKFYKSKSEQDK---------------------------VNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKG--WDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T +AT+ P     HP+NA   M+R+    + + N +    T     F  +L+ V  +Y        PT  D   A   + R+ + Y++    IS G +      + M +++   L +   S+   YH+++  W    L+  +   ++  ++   ++   + A++       A+ L + +++            K F+ +L E+  K    K E+D+                              E   +     S L CR + N+    N R     +K+   WDR         P I +Y+ +++D +I  V  + K    +  V+    G L   +    + A     ++  ++ ++++I   TGLE         + ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VF  V  ++  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:   67 TITATQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTT---NGFISNLT-VQRQYF-------PTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTEL--WMAQALSQLDEGEESPIDKV-TVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQL-EKQRKAENEKKEEDQKRVLDKRDAQRKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNR---NPRLLLAPVKQEDEWDR---------PRIVRYHEIISDSEIETVKEMAKPRLKRATVHDPITGKLTTAQYRVSKSAWLSGYEHSTIERINQRIEDVTGLE---------MDTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 530
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: p4ha1b (prolyl 4-hydroxylase, alpha polypeptide I b [Source:ZFIN;Acc:ZDB-GENE-030131-4089])

HSP 1 Score: 106.301 bits (264), Expect = 9.879e-24
Identity = 113/502 (22.51%), Postives = 208/502 (41.43%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQ--ESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIRE-----------KLFDNKLLERDLKFYKSKSEQDK---------------------------VNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKG--WDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T +AT+ P     HP+NA   M+R+    + + N +    T     F  +L+ V  +Y        PT  D   A   + R+ + Y++    IS G +      + M +++   L +   S+   YH+++  W    L+  +   ++  ++   ++   + A++       A+ L + +++            K F+ +L E+  K    K E+D+                              E   +     S L CR + N+    N R     +K+   WDR         P I +Y+ +++D +I  V  + K    +  +     GVL        + A     ++  ++ ++++I   TGLE         + ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VF  V  ++  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:   67 TITATQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTT---NGFISNLT-VQRQYF-------PTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTEL--WMAQALSQLDEGEESPIDKV-TVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQL-EKQRKAENEKKEEDQKRVLDKRDAQRKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNR---NPRLLLAPVKQEDEWDR---------PRIVRYHEIISDSEIETVKEMAKPRLRRATISNPITGVLETAPYRISKSAWLSGYEHSTIERINQRIEDVTGLE---------MDTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 530
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: p4ha1b (prolyl 4-hydroxylase, alpha polypeptide I b [Source:ZFIN;Acc:ZDB-GENE-030131-4089])

HSP 1 Score: 106.301 bits (264), Expect = 9.879e-24
Identity = 113/502 (22.51%), Postives = 208/502 (41.43%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQ--ESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIRE-----------KLFDNKLLERDLKFYKSKSEQDK---------------------------VNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKG--WDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T +AT+ P     HP+NA   M+R+    + + N +    T     F  +L+ V  +Y        PT  D   A   + R+ + Y++    IS G +      + M +++   L +   S+   YH+++  W    L+  +   ++  ++   ++   + A++       A+ L + +++            K F+ +L E+  K    K E+D+                              E   +     S L CR + N+    N R     +K+   WDR         P I +Y+ +++D +I  V  + K    +  +     GVL        + A     ++  ++ ++++I   TGLE         + ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VF  V  ++  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:   67 TITATQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTT---NGFISNLT-VQRQYF-------PTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTEL--WMAQALSQLDEGEESPIDKV-TVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQL-EKQRKAENEKKEEDQKRVLDKRDAQRKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNR---NPRLLLAPVKQEDEWDR---------PRIVRYHEIISDSEIETVKEMAKPRLRRATISNPITGVLETAPYRISKSAWLSGYEHSTIERINQRIEDVTGLE---------MDTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 530
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: p4ha1a (prolyl 4-hydroxylase, alpha polypeptide I a [Source:ZFIN;Acc:ZDB-GENE-040724-91])

HSP 1 Score: 102.834 bits (255), Expect = 1.361e-22
Identity = 109/483 (22.57%), Postives = 199/483 (41.20%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINP----MLLDEMIVLAQ--ESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLK--FYKSKSEQDKV-NAENQNINLSNNSDLLCRE-NYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVL-NANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRIS------------SSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T +A + P     HP+NA   M+R+      + + +            +D+S      +  +   +P   D   A   + R+ + YK+    IS G +    +  P    + +++   L +   S+   YH+++  W           +K  D    + V +  A  + +     ++    E+ R   +  +LL  D K  +   K + +K+   E   +       L CR  N N   +Y +     + +  WDR         P I +Y+ ++ +++I ++  L K    +  +     GVL  A+ + +K  A   D     + +   ++S    L    H    RI+            ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VFP+V  ++   +GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:   71 TATAVQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVL-----------KDMSDGFISNLTIQRQYFPNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTEL--W-------MAQALKQLDEGEESSVEIATALDYLSY----SVYQQGELERALEYTKRLLTVDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPV--KQEDEWDR---------PRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLETAHYRISKRRATVHDPQTGKLTTAQYRVSKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 516
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Match: p4ha1a (prolyl 4-hydroxylase, alpha polypeptide I a [Source:ZFIN;Acc:ZDB-GENE-040724-91])

HSP 1 Score: 102.834 bits (255), Expect = 1.361e-22
Identity = 109/483 (22.57%), Postives = 199/483 (41.20%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINP----MLLDEMIVLAQ--ESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLK--FYKSKSEQDKV-NAENQNINLSNNSDLLCRE-NYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVL-NANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRIS------------SSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T +A + P     HP+NA   M+R+      + + +            +D+S      +  +   +P   D   A   + R+ + YK+    IS G +    +  P    + +++   L +   S+   YH+++  W           +K  D    + V +  A  + +     ++    E+ R   +  +LL  D K  +   K + +K+   E   +       L CR  N N   +Y +     + +  WDR         P I +Y+ ++ +++I ++  L K    +  +     GVL  A+ + +K  A   D     + +   ++S    L    H    RI+            ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VFP+V  ++   +GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:   71 TATAVQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVL-----------KDMSDGFISNLTIQRQYFPNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTEL--W-------MAQALKQLDEGEESSVEIATALDYLSY----SVYQQGELERALEYTKRLLTVDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPV--KQEDEWDR---------PRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLETAHYRISKRRATVHDPQTGKLTTAQYRVSKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 516
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 119.783 bits (299), Expect = 5.290e-28
Identity = 124/489 (25.36%), Postives = 215/489 (43.97%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRI----VFHLNPILNRI---FTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQE--SNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAA---------ALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCR-ENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPP----------IYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T++ATK P     HP+NA   M+R+    V   N IL  I   F S   ++R ++                  P   D   A   + R+ + Y +    ISKG +        +  ++   L +   ++   YH+++  W E  L+  ++  +++ ++   L  +  A         AL  TK   E    L  I+ ++   +     +    +++  + K + E +        + LCR E    +     R F R     +D  K  LL ++P           I +Y+ +++DE+I +V  L K    +  +     GVL   +    + A     +  V+  L+R+I   TGL+         +S++   +V NYGIGG  E   D+L K + +  K +    G+R+ATW ++++D   GG  VFP+V  ++  ++GT + W+NLL++G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:   67 TDTATKDPEGYLGHPVNAFKLMKRLNTEWVKLENLILKDISDGFISNLTIQRQYF------------------PNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTEL--WMEQALSQLDAGEESSLDKVMVLDYLSYAVYQQGDLDKALTLTKRSLEGNGNLRHIMSKESNKSSSSPSEGAELRTRKGRPKDHLEKEKY------EKLCRGEGVKMTSRRQKRLFCRY----FDGKKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVVARLNRRIEGVTGLD---------MSTAEELQVANYGIGGQYEPHFDFLRKYEPDAFKKLGT--GNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 514
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 116.316 bits (290), Expect = 8.855e-27
Identity = 128/514 (24.90%), Postives = 222/514 (43.19%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRI----VFHLNPILNRI---FTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQES--NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAA---------ALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCR-ENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPP----------IYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTR------------KCYRKTASFF*KDSF 1820
            T++ATK P     HP+NA   M+R+    V   N IL  I   F S   ++R ++                  P   D   A   + R+ + Y +    ISKG +        +  ++   L + +  +   YH+++  W E  L+  ++  +++ ++   L  +  A         AL  TK   E    L  I+ ++   +     +    +++  + K + E +        + LCR E    +     R F R     +D  K  LL ++P           I +Y+ +++DE+I +V  L K    +  +     GVL   +    + A     +  V+  L+R+I   TGL+         +S++   +V NYGIGG  E   D+L K + +  K +    G+R+ATW ++++D   GG  VFP+V  ++  ++GT + W+NLL++G  +  + H  CPV  G+KWV  K+IHE G  F R            KC  K   +F  +S+
Sbjct:   67 TDTATKDPEGYLGHPVNAFKLMKRLNTEWVKLENLILKDISDGFISNLTIQRQYF------------------PNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTEL--WMEQALSQLDAGEESSLDKVMVLDYLSYAVYQQGDLDKALTLTKRSLEGNGNLRHIMSKESNKSSSSPSEGAELRTRKGRPKDHLEKEKY------EKLCRGEGVKMTSRRQKRLFCRY----FDGKKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVVARLNRRIEGVTGLD---------MSTAEELQVANYGIGGQYEPHFDFLRKYEPDAFKKLGT--GNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPSKIRSERSCFCKCAPKCHYYFMPESY 539
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 111.694 bits (278), Expect = 1.494e-25
Identity = 68/205 (33.17%), Postives = 111/205 (54.15%), Query Frame = 3 
Query: 1170 PPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            P I +Y+ +++DE+I +V  L K    +  +     GVL   +    + A     +  V+  L+R+I   TGL+         +S++   +V NYGIGG  E   D+L K + +  K +    G+R+ATW ++++D   GG  VFP+V  ++  ++GT + W+NLL++G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:  248 PRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVVARLNRRIEGVTGLD---------MSTAEELQVANYGIGGQYEPHFDFLRKYEPDAFKKLGT--GNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 441
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 106.686 bits (265), Expect = 9.422e-24
Identity = 65/205 (31.71%), Postives = 110/205 (53.66%), Query Frame = 3 
Query: 1170 PPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            P I +Y+ +++DE+I +V  L K    +  +     GVL   +    + A     +  V+  L+R+I   TGL+         +S++   +V NYG+GG  E   D+  K + +  K++    G+R+ATW ++++D   GG  VFP+V  ++  ++GT + W+NL ++G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:  324 PRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRISKSAWLSAYEDPVVARLNRRIEGVTGLD---------MSTAEELQVANYGMGGQYEPHFDFARKDEPDAFKELGT--GNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLFESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 517
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 105.531 bits (262), Expect = 2.333e-23
Identity = 114/481 (23.70%), Postives = 207/481 (43.04%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRI----VFHLNPILNRI---FTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQE--SNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCR-ENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPP----------IYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFG-GDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T++ATK P     HP+NA   M+R+    V   N IL  I   F S   ++R ++                  P   D   A   + R+ + Y +    ISKG +        +  ++   L +   ++   YH+++  W E  L+  ++  +++ ++   L  + + A++   +  +A+ L +  +            +L F+ S +E        ++       + LCR E    +     R F R     +D  K  LL ++P           I +Y+ +++DE+I +V  L K    +  +     GVL   +    + A     +  V+  L+R+I   TGL+         +S++   +V     G   ++  D L    + +       G G+R+ATW ++++D   GG  VFP+V  ++  ++GT + W+NLL++G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:   67 TDTATKDPEGYLGHPVNAFKLMKRLNTEWVKLENLILKDISDGFISNLTIQRQYF------------------PNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTEL--WMEQALSQLDAGEESSLDKVMVLDYL-SYAVYQQGDLDKALTLTKRSL------------ELGFHDSGAELRTRKGRPKDHLEKEKYEKLCRGEGVKMTSRRQKRLFCRY----FDGKKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVVARLNRRIEGVTGLD---------MSTAEELQVK----GNIMDVGSDELLHFKKYEPDAFKKLGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 497
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide [Source:MGI Symbol;Acc:MGI:894286])

HSP 1 Score: 111.309 bits (277), Expect = 2.480e-25
Identity = 110/421 (26.13%), Postives = 192/421 (45.61%), Query Frame = 3 
Query:  600 WPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEII-----REKLFDN-KLLERDLKFYKSKS---EQDKVNAENQNINLSNNSDLLCRENYNS-SEYYNLRCFYRRIKKGWDRA----KVELLNM----------NPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +PT  D   A   + R+ + YK+    IS+G +   T    ML +D+   L + + N  +Y+  VL W E +L   ++  +    +   L  + + A+F   +   A+ L   ++      E+   N +  ER L+  + KS   + D   A  +N+       L  R+ Y S      ++   RR KK + R     +V  L +          +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+     +E+     +  G+R+AT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:  125 FPTDEDESGAARALMRLQDTYKLDPDTISRGELPG-TKYQAMLSVDDCFGLGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATVTKSLVLDYL-SYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGMGGQYEPHFDF--SRSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 531
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide [Source:MGI Symbol;Acc:MGI:894286])

HSP 1 Score: 111.309 bits (277), Expect = 2.632e-25
Identity = 111/421 (26.37%), Postives = 191/421 (45.37%), Query Frame = 3 
Query:  600 WPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEII-----REKLFDN-KLLERDLKFYKSKS---EQDKVNAENQNINLSNNSDLLCRENYNS-SEYYNLRCFYRRIKKGWDRA----KVELLNM----------NPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +PT  D   A   + R+ + YK+    IS+G +   T    ML +D+   L + + N  +Y+  VL W E +L   ++  +    +   L  + + A+F   +   A+ L   ++      E+   N +  ER L+  + KS   + D   A  +N+       L  R+ Y S      ++   RR KK + R     +V  L +          +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+  +  +   K      G+RLAT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:  125 FPTDEDESGAARALMRLQDTYKLDPDTISRGELPG-TKYQAMLSVDDCFGLGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATVTKSLVLDYL-SYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTE----GNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide [Source:MGI Symbol;Acc:MGI:894286])

HSP 1 Score: 111.309 bits (277), Expect = 2.632e-25
Identity = 111/421 (26.37%), Postives = 191/421 (45.37%), Query Frame = 3 
Query:  600 WPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEII-----REKLFDN-KLLERDLKFYKSKS---EQDKVNAENQNINLSNNSDLLCRENYNS-SEYYNLRCFYRRIKKGWDRA----KVELLNM----------NPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +PT  D   A   + R+ + YK+    IS+G +   T    ML +D+   L + + N  +Y+  VL W E +L   ++  +    +   L  + + A+F   +   A+ L   ++      E+   N +  ER L+  + KS   + D   A  +N+       L  R+ Y S      ++   RR KK + R     +V  L +          +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+  +  +   K      G+RLAT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:  125 FPTDEDESGAARALMRLQDTYKLDPDTISRGELPG-TKYQAMLSVDDCFGLGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATVTKSLVLDYL-SYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTE----GNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide [Source:MGI Symbol;Acc:MGI:97463])

HSP 1 Score: 104.375 bits (259), Expect = 2.695e-23
Identity = 61/205 (29.76%), Postives = 108/205 (52.68%), Query Frame = 3 
Query: 1170 PPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVY-LEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            P I +++ +++D +I  V +L K    +  V+  E G L   +    + A     +  V+  ++ +I   TGL+         +S++   +V NYG+GG  E   D+  K + +  +++    G+R+ATW ++++D   GG  VFP+V  S+  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K++HE G  F R C
Sbjct:  255 PRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLD---------VSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGT--GNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPC 448
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Match: P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide [Source:MGI Symbol;Acc:MGI:97463])

HSP 1 Score: 103.605 bits (257), Expect = 7.940e-23
Identity = 61/205 (29.76%), Postives = 108/205 (52.68%), Query Frame = 3 
Query: 1170 PPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVY-LEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            P I +++ +++D +I  V +L K    +  V+  E G L   +    + A     +  V+  ++ +I   TGL+         +S++   +V NYG+GG  E   D+  K + +  +++    G+R+ATW ++++D   GG  VFP+V  S+  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K++HE G  F R C
Sbjct:  335 PRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLD---------VSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGT--GNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPC 528
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q10576|P4HA1_CAEEL (Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabditis elegans OX=6239 GN=dpy-18 PE=1 SV=2)

HSP 1 Score: 130.954 bits (328), Expect = 6.597e-31
Identity = 126/502 (25.10%), Postives = 231/502 (46.02%), Query Frame = 3 
Query:  417 ESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRY--IREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLS-----------NNSD-----LLCRENYNSSE--YYNLRCFYRRIKK--GWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKT--SKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRKTASFF*KDSFQNEFCSNLG 1847
            E+  K  TN PINA   ++R +F    I +++  +K          +SS+ D    +R     +PT  DL  A  G+ R+ + Y++   +++ G I+           +   +A+ + N  +++  V+ W E        E++    +  +++   A AL+   N K A+ L EE+ +      +  + ++K+Y+   EQ+ V   +   NL             N++      LCR     S+     L C+Y+R +    +   KVE+   NP    +  V++D+++  +  L K   ++   H  +   ++ A  + +K  A   + + DV+++++++I + T LE         + ++   ++ NYGIGG+ +   D+     EE K   S+  G+R+AT  ++++    GG  VF + K ++L  +   L W+NL K G  NP + H  CPV  G KWV  K+IHE GN F R C  K++ +         F  +LG
Sbjct:   69 ENGLKDITN-PINAFLLIKRKIFDWKEIESKMNANKA------GNVVSSITDDSYGVR-----YPTADDLSGAAIGLLRLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVM-WMEEAQRRLGDEVEPT-VEVEDILEYLAFALYKQNNLKHALKLTEELYKMNPTHPRA-KGNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEVPVSQKDISRLYCYYKRDRPFLVYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKS-AWLKEWEGDVVETVNKRIGYMTNLE---------METAEELQIANYGIGGHYDPHFDH--AKKEESKSFESLGTGNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRPCGLKSSDY-------ERFVGDLG 536
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|O15460|P4HA2_HUMAN (Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 5.939e-25
Identity = 114/482 (23.65%), Postives = 207/482 (42.95%), Query Frame = 3 
Query:  444 HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFES--EIKNNDNQF---------------RNLVRMKAAALFNTKNEKEAINL--LEEII---REKLFDNK----------LLERDLKFYKSKSEQDKV-NAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            HP+NA   ++R        LN   T    L+    QD ++     +  +   +PT  D   A   + R+ + Y++    IS+G +   T    ML +D+   + + + N  +Y+  VL W E +L   ++  E     +Q                R L   +     +  +E+   NL   E+++   REK   N+          + ER + +   +   + +   E   +       L CR ++ +     L   ++  +  WD         +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+    ++E+     +  G+R+AT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:   82 HPVNAYKLVKR--------LN---TDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPG-TKYQAMLSVDDCFGMGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKE-EDEWD---------SPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGVGGQYEPHFDF--SRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q60716|P4HA2_MOUSE (Prolyl 4-hydroxylase subunit alpha-2 OS=Mus musculus OX=10090 GN=P4ha2 PE=1 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 2.060e-24
Identity = 109/421 (25.89%), Postives = 192/421 (45.61%), Query Frame = 3 
Query:  600 WPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPML-LDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEII-----REKLFDN-KLLERDLKFYKSKS---EQDKVNAENQNINLSNNSDLLCRENYNS-SEYYNLRCFYRRIKKGWDRA----KVELLNM----------NPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +PT  D   A   + R+ + YK+    IS+G +   T    ML +D+   L + + N  +Y+  VL W E +L   ++  +    +   L  + + A+F   +   A+ L   ++      E+   N +  ER L+  + KS   + D   A  +N+       L  R+ Y S      ++   RR KK + R     +V  L +          +P I +YY V++DE+I  +  + K    +  V   K GVL        + +   ++D  V+  ++R++ H TGL          + ++   +V NYG+GG  E   D+     +++     +  G+R+AT+  +++D   GG  VFP +  ++  ++GT + W+NLL++G  +  + H  CPV  G KWV  K+ HE G  F R C
Sbjct:  125 FPTDEDESGAARALMRLQDTYKLDPDTISRGELPG-TKYQAMLSVDDCFGLGRSAYNEGDYYHTVL-WMEQVLKQLDAGEEATVTKSLVLDYL-SYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLT---------VKTAELLQVANYGMGGQYEPHFDF--SRSDDEDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 531
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q20065|P4HA2_CAEEL (Prolyl 4-hydroxylase subunit alpha-2 OS=Caenorhabditis elegans OX=6239 GN=phy-2 PE=1 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 5.629e-24
Identity = 128/525 (24.38%), Postives = 224/525 (42.67%), Query Frame = 3 
Query:  285 VKAILNGYKTLEEDRYD--KRNAKDYTELDGEIRKTLEILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQES-NRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIR---------------EKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYY---NLRCFYRRIKKGWDRA--KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYL--EKGVL-NANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            V  I++ Y   E  R D  +R A +Y   +                ES       +PINA   ++R+      + N +  +K      F   L ++ D  +R E   +P   DL  A + + R+ + Y +   ++S GII      N +   +   + + + N+K+Y+   L W +  L   E+E      ++  ++   A +L+   N + A++L + + +               E +   K +  DL    +K        E   I   +  + LCR      E      LRC+ +R K     A  KVE+L  +P    +  V++D +I EV   + + K+K+      + G L +A  + +K   +  D D  V+  ++R+I   T L           ++S   +V NYG+GG+ +   D+     EEK    ++  G+R+AT  ++++    GG  VF  +  ++   +   L W+NL ++G  +  + H  CPV  G KWV  K+IHE G  FTR C
Sbjct:   35 VTTIIDQYIEAERARLDDLRRYAHEYVHRNAH-------------AESVGPEFVTNPINAYLLIKRLTTEWKKVENIMLNNKA---STF---LKNITDNRVRSEVK-FPGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYH-CLMWMQVALVKIENENPPTIEEWE-ILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDMLQGKDMVGDLPPIVNK------RVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEI-EVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDLD-PVIDRVNRRIEDFTNLNQ---------ATSEELQVANYGLGGHYDPHFDF--ARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPC 518
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Match: sp|P16924|P4HA1_CHICK (Prolyl 4-hydroxylase subunit alpha-1 OS=Gallus gallus OX=9031 GN=P4HA1 PE=1 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 2.843e-22
Identity = 62/205 (30.24%), Postives = 103/205 (50.24%), Query Frame = 3 
Query: 1170 PPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVY-LEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            P I ++  +++DE+I  V  L K    +  V+  E G L        + A     +  V+  ++ +I   TGL+         +S++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VFP+V  S+  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K++HE G  F R C
Sbjct:  317 PRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPVVSRINTRIQDLTGLD---------VSTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPC 510
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: A0A210QXI6 (Prolyl 4-hydroxylase subunit alpha-1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT23438 PE=4 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 8.362e-43
Identity = 134/546 (24.54%), Postives = 241/546 (44.14%), Query Frame = 3 
Query:  225 GHCSVSASGLRDSYFVEGQLVKAILNGYKTLEEDRYDKRNAKDYTELDGEIRKTLEILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECS-----CWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFR--NLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSK-------SEQDKVNAENQNINLSNNSDLLCRENYNSSEY-YNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVF----GGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRKTASFF 1805
            GH   S   +   Y  EG+L +A++         RY   +  + T +  ++ K +E +   R T         HPINAL  + R+      +   IF            D  +  D  I ++ +      WPT  D+  AV GI R+  +Y++    +  G +   +S NP+   EM+ +A+ +     H D + W   LL         +D++F    L ++ A+A +      +A+ +LE+    K   N       +FYK++       + ++K+             + LCR    S++    L+CF    +  + + + E++N  P I  Y+ V+++ ++  + N  + S     ++ E G      K   + A   D D+ ++  L+++IS  TGL+     +   +SS   ++V+NYG+GG      D+L K    +            GDR+ATW ++L+    GG  VFP +K  + + +G+ + W+N L NG+ N    H  CPV  G+KWV  K+I ++G +  + C +   + F
Sbjct:   20 GHIFSSVQRVETLYEEEGRLTRALM---------RYKDTSVNNGTHVGDKVIKFVENIYTQRSTVDDAGLWVGHPINALRLILRVAEDWEKVFEEIFCDDC-------PDTYAAKDLQISKKIALNAVKIWPTKDDILGAVRGILRLWRIYQLDLQQLVNGTVLQESS-NPLSWREMLAIARGAIDLGMHYDGITWMTSLLETNSKGQLGSDSKFEEDTLRKILASAYYQVGMAWKAVEVLEKSDASKRGSN------YEFYKTRLAALPKGTSREKLQPPEYTDRYQAPYEALCRGPLKSAKMQARLKCFLTNTRIPFYKIRAEIVNSKPIIIIYHNVISNSEMEFLRNEGEKSLTYSKIFAESGQHLMANKRVSQTAWLKDTDHHLLLRLNKRISTITGLDMT---FRDHLSSVERYQVVNYGVGGEYGPHNDHLGKPLWGRGGLPEALEINDSGDRIATWMFYLSSVKAGGATVFPLLKARVPVTEGSAVFWYNTLPNGSTNKKMMHAGCPVLLGTKWVANKWIRQHGQVLRKLCGKTEKANF 539
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: R7UVX5 (Fe2OG dioxygenase domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_174752 PE=4 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 1.410e-39
Identity = 127/480 (26.46%), Postives = 215/480 (44.79%), Query Frame = 3 
Query:  423 ATKTPTNHPINALHFMRRI--VFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLE---------EIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENY-----NSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANE---------KYAKEEAIFWDEDYD-VMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSV-FGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +T +   HP+NALH + R   V     +   ++T   + +R  + DLS  L           P   D   ++  + R+   Y++P + ++ G++   ++ +PM   EM  + + S R       ++W +  +   +      D         +  A ++T     A+N+L+         E I  KL D + +   +   K+K+   +       +  +   + LCR          SE   L+C Y+     + R K E+LN  P I  ++ V++D +        KT K++    LE+  +  NE         K   + +  WD+  +  +  LSR+++  TGL+T      + + S+ PF+++NYGIGG  E  VDY A           V   G+RLAT+ ++L D   GG  VFPK+K+ +   +     W+N+  NG V+PL+EH  CPV  G KWV  K+IHE+G    R C
Sbjct:   75 STASYVGHPVNALHIISRWGDVQEQASMGGDLWT---VTRRELHTDLSVTL-----------PDSRDFFGSIEALVRLQETYQLPTSELANGVVHGDSADHPMSGFEMYAMGKASLRAGSFGQAVQWLDLAIAAKDGSFSPEDAMADLADAYQLIADYST-----AVNVLQLAHENAPGNEAIASKLEDFRRINNTMGSTKAKTAWRR-----PKLKSTKAYEALCRGEQLKLPDVDSEQQALKCRYKPGILPFVRYKEEMLNRKPHIVLFHDVMSDAE-------AKTMKMEAMHKLERAHVADNENKHGHSASAKRISQVSWLWDDHANKTIHQLSRRVADITGLQTG---VVSGLHSAEPFQILNYGIGGQYEPHVDYFAGNHSHSSLPEHVRASGNRLATFMFYLNDVHAGGATVFPKLKVGIPPTKNGAAFWYNIGLNGDVDPLTEHAGCPVLLGQKWVANKWIHEHGQDQYRTC 520
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: K1Q8K9 (KRR1 small subunit processome component-like protein OS=Crassostrea gigas OX=29159 GN=CGI_10024541 PE=4 SV=1)

HSP 1 Score: 164.466 bits (415), Expect = 9.771e-39
Identity = 140/530 (26.42%), Postives = 227/530 (42.83%), Query Frame = 3 
Query:  315 LEEDRYDKRNAKDYTELDGEIRKTLEILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTS----------------KTLLKRNFYQD--LSSVLD-----RYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDL----LCRENYNS-SEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEK--YAKEEAI-----FW--DEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDY----LAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            L+  RY     ++  ++  EI +  E L   R+T +       HP+N  H + R V     + + IF                   T+++   + D  L    D     + + +    WP+  DL  A S + R+  VYK+       GI+  +T+  PM  DE++ +A+ ++        + W + L    ++E   + NQ   ++R     +F          +LE     +  +N+ +  D+ FY S +  D    EN+ I      D     LCRE   S  E   LRCF R     + +AK E++N  P I  ++ V++   I  + ++      +  V+LE    N      Y K++ I      W   ++Y  +  L  +I   TGL   + +Y    S S  F+V+NYG+GG      DY    L  +      +     GDR+ATW +++ D   GG  VFP+V+  + + +G    WFNL  +G  +P + H  CPV  GSKWV  K+I E G M  R C
Sbjct:  364 LDLSRYISSVQENEQDVPLEILRFSESLKIKRKTINDGSAYIEHPVNDFHLLYRFVVEWQSVFDIIFCKDCEETEAAKGAKGSPFATVIQLPMHLDGHLGEKGDFNFTVQLVSKRLGLWPSSYDLDGASSALLRLWKVYKLDLNEFINGIVQTYTADQPMSDDEVLTVAKFADSVKDDYSEMRWLKALYKRLQTEDGFSHNQ-TTVIRFPKKGIF----------ILEPF---QSLENRDINSDVAFYLSNATSD----ENETIPEPATEDAMYEALCREEQKSLHELAKLRCFLRDTVIPYYKAKEEVVNYEPRIAIFHDVISSTSIEHLKSIASKGLTRSTVFLENTGPNGQVTITYGKQDNIRVSQTCWIRTDEYPELLRLENRIQLITGL---SAEYKPVRSHSEKFQVVNYGVGGMYTAHHDYTGYKLGIISNPMDSEDISTSGDRMATWMFYMNDAKAGGATVFPEVRTRIPVAKGGAAFWFNLRPSGATDPRTLHGGCPVLVGSKWVTNKWIREEGQMDRRLC 872
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: K1QGQ1 (Prolyl 4-hydroxylase subunit alpha-1 OS=Crassostrea gigas OX=29159 GN=CGI_10024543 PE=4 SV=1)

HSP 1 Score: 159.073 bits (401), Expect = 9.372e-38
Identity = 125/480 (26.04%), Postives = 207/480 (43.12%), Query Frame = 3 
Query:  390 EILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDL----LCRENYNS-SEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAK-------EEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDY----LAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            E L   R+T         HP+N  H + R V     + + I+  K     +  +D +  + + + +    WP+  DL  A S + R+  VYK+       GI+  +T+  PM  DE++ + +                     F   +K++ ++ R L      AL+     ++  +  +  +      N+ + RD+ FY S +  +    EN+ I      D     LCRE   S  E   LRCF R     + +AK E++N  P I  ++ V++   I  + ++      +  V+LE    + +  Y K       + +    ++Y  +  L  +I   TGL     +Y +  S S  F+V+NYG+GG   +  DY    L         D     G+R+ATW ++L D   GG  VFP+VK  + + +G    W+N+  +G  +P + H  CPV  GSKWV  K+I E G M  R C
Sbjct:  138 ESLKIKRKTIKDVYRYIEHPVNDFHLLYRFVVEWQSVFDNIWC-KDCEDTDAAKDFNFTV-QLVSKRLGLWPSSYDLDGASSALLRLWKVYKLDLNEFINGIVQTYTADQPMSDDEVLTVVK---------------------FADSVKDDYSEMRWL-----EALYKRLQTRDGFSYNQTTV----IHNRGINRDVAFYLSSANSN----ENETIPEPTPKDAMYEALCREEQKSLQELAKLRCFLRETVIPYYKAKEEVVNYEPRIAIFHDVISPTSIEHLKSVASKGFTRSTVFLENTGPDGHVTYGKLDNVRVSQTSWLGTDEYPELSRLENRIKLTTGLSA---EYKSVRSHSEKFQVLNYGVGGMYTVHYDYTGYMLGIPSNPLDSDDIRTSGERMATWMFYLNDVKAGGATVFPEVKTRIPVAKGGAAFWYNVRPSGATDPRTLHGGCPVLVGSKWVSNKWIREEGQMDRRLC 578
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Match: A0A0L8FTK8 (Fe2OG dioxygenase domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22008289mg PE=4 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.051e-37
Identity = 112/405 (27.65%), Postives = 201/405 (49.63%), Query Frame = 3 
Query:  600 WPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNF-ESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSK------SEQDKVNAENQNINLSNNSDLLCR--ENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXS--VFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            WPT  D+  A  G+ R+ N+Y +    + +G I N T   PM  ++++ L + +N  +   + + W   L   + +S+I+    +   + R  A+A         +++ +E+ ++ K  D K  +R+  F + K      S++ K+  +  N + S+    LCR  +  +SS    L+C +R  +  + R K E+++  P I  ++ V+ DE+I  +    +       V  +  +         + A  WD D  V++ LS +I   TGL   N +    +S++ P +V+NYG+G   E  VDY    ++ +K      +  GDR+ATW  ++++   GG  +FPK+ + + + +G+ + W+NL +N   +P + H  CPVA GSKWV  K+IHE   MF R C
Sbjct:  138 WPTKKDVTEAALGLFRLQNIYSLNLTELLQGRIAN-TQTEPMTANDVLKLIEIANEHDMVYEEILWLLALDELYRKSKIEKGTVEQNQIYRTIASAYSMYGMPWVSLDYIEKCLKIKTND-KGCQREKTFLQKKLKSIPGSKRTKIFEKPIN-STSSQYQALCRGEDLLSSSRRAQLKCIWRPTENHYSRVKEEIMSYKPKIVVFHDVITDEEIQYILEESQQKFNSSKVGDDDIIQGMKTDIISQRAWLWDSD-PVLRRLSHRIGSITGL---NTQLKVFVSNAEPLQVLNYGLGAMYEPRVDYFESKEQLEKSASQFLIGSGDRIATWMLYMSNVTLGGATIFPKINVQIPVIKGSAVFWYNLKRNQRRDPKTLHASCPVAVGSKWVANKWIHEVEQMFQRPC 535
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Match: p4ha1a (prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI gene;Acc:103044793])

HSP 1 Score: 112.464 bits (280), Expect = 8.452e-26
Identity = 115/502 (22.91%), Postives = 203/502 (40.44%), Query Frame = 3 
Query:  414 TESATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINP----MLLDEMIVLAQ--ESNRKNYHS-------------------------DVLEWAEFLLNNFESEIKNN------DNQFR----NLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCR-ENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            T +AT+ P     HP+NA   M+R+      + + +            +D+S      +  +   +P   D   A   + R+ + Y++    IS G +   TS  P    + +D+   L +   S+   YH+                         D L ++ +     E  +++       D++ +    NL   +       K EKE     EE  +     N  L    K+ K          E   +     S L CR  + N   YY L     + +  WDR         P I +Y+ +++D+++ +V  L K    +  +     GVL        + A     ++ V+  ++++I   TGL+         ++++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VFP+V  ++   +GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  F R+C
Sbjct:   70 TATATQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVL-----------KDMSDGFISNLTIQRQYFPNDEDQTGAAKALLRLQDTYRLDTHTISSGNLPGVTSDLPYKSTLTVDDCFELGKIAYSDADYYHTELWMGQALRQLDKGEESSIDSVTVLDYLSYSVYQQGELEKALEHTKRLLTLDSEHQRANGNLKYFEYQLAKQRKAEKEQKGTTEERTKRDTEKNSFLPEKRKYEKL------CRGEGLRLTPRRQSRLFCRFHDNNRHPYYILGPV--KQEDEWDR---------PRIVRYHNIISDKEMEKVKELSKPRLRRATISNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIQDITGLD---------VTTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAIKPMKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRRC 532
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Match: p4ha2 (prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI gene;Acc:103035211])

HSP 1 Score: 107.071 bits (266), Expect = 4.917e-24
Identity = 65/206 (31.55%), Postives = 103/206 (50.00%), Query Frame = 3 
Query: 1167 NPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +P I +Y   L+DE++  +  L K    +  V   K GVL   +    + A   DED  V++ ++++I   TGL  +  +           +V NYG+GG  E   D+     +E     S+  G+R+AT+  +++D   GG  VFP    ++   +GT + W+NL ++G  +  + H  CPV  GSKWV  K+IHE G  F R C
Sbjct:  342 SPHIVRYLEALSDEEMNRIKELAKPKLARATVRDPKTGVLTTAQYRVSKSAWLEDEDDLVIRRVNQRIEDVTGLTVDTAEL---------LQVANYGVGGQYEPHFDF--SRKDEPDAFKSLGTGNRVATYLNYMSDVDAGGATVFPDFGAAIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLIGSKWVSNKWIHERGQEFRRPC 536
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Match: zgc:152670 (zgc:152670 [Source:ZFIN;Acc:ZDB-GENE-060929-954])

HSP 1 Score: 99.3673 bits (246), Expect = 4.298e-22
Identity = 103/414 (24.88%), Postives = 179/414 (43.24%), Query Frame = 3 
Query:  579 IREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLER-DLKFYKSKSEQDKVNAENQNINLSNNS--DLLCR-ENYNSSEYYNLRCFYRRIKKG-------WDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFW--DEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            + EE    PT  D+  A  GI R+  +YK+   NI+   +   +S +   L ++       + ++Y    L + + L     ++ +N+D   + L+   +++ +   +   A+   ++  R  +    L  R DL  YK K  Q     +   ++ ++ S  + LCR E  N +     R    R   G       +   K E +  +PPI  Y+ V ++ +I ++ NL +       + L   +   N          W  DED  V+ S+S+++S  TGL          + S+   +V+NYG+GG+     D                           L+D   GG  VFP++  S+  ++G+ ++W+NLL+NG  +  S H  CPV  GSKWV  K++HE G  F R+C
Sbjct:    1 MEEEFHELPTEDDVDGAALGIIRLQEMYKLYPENITTNPLTGQSSGSVFKLGKVAY-----SHESYQHAFLWFFKSLQKLQATKEENSDTYKKLLLEYLSSSAYEFGHVPLAVYCAKQ--RVNIDPGDLQARLDLTVYKGKLSQHTKTPDIFTLSETSTSTYEALCRGEELNMASSTLTRQLSCRYSTGGGNPRLMYAPVKEEEVWDDPPIMTYHDVFSEAEIEQLKNLSRPGDRAPLLPLIMILTVINHS-------VWLKDEDAPVVSSVSQRLSDITGL---------GMESAESLQVLNYGVGGHFSPHYDT--------------------------LSDVSYGGSTVFPEIGASVKPQKGSVVMWYNLLRNGQGDWRSLHGGCPVYQGSKWVAVKWVHERGQEFRRQC 365
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha-1-like [Source:NCBI gene;Acc:103026899])

HSP 1 Score: 100.908 bits (250), Expect = 5.306e-22
Identity = 62/217 (28.57%), Postives = 108/217 (49.77%), Query Frame = 3 
Query: 1134 WDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLE-KGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            WDR         P I +++ +++D +I +V  L K    +  V+    G L   +    + A    +++ V++ ++++I   TGLE         + ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VF  V  ++  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  F R C
Sbjct:  338 WDR---------PHIVRFHDIISDYEISKVKELAKPRLRRATVHDPITGKLTTAQYRVSKSAWLTADEHPVIERINQRIEDLTGLE---------MDTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRVATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPC 534
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Match: zgc:152670 (zgc:152670 [Source:ZFIN;Acc:ZDB-GENE-060929-954])

HSP 1 Score: 99.3673 bits (246), Expect = 5.602e-22
Identity = 79/279 (28.32%), Postives = 128/279 (45.88%), Query Frame = 3 
Query:  975 DLKFYKSKSEQDKVNAENQNINLSNNS--DLLCRE---NYNSSEYYNLRCFYRR----IKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTS-KIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            DL  YK K  Q     +   ++ ++ S  + LCR    N  S     L C Y       +  +   K E +  +PPI  Y+ V ++ +I ++ NL +       HV+L+                  DED  V+ S+S+++S  TGL          + S+   +V+NYG+GG+     D + + + +     S             L+D   GG  VFP++  S+  ++G+ ++W+NLL+NG  +  S H  CPV  GSKWV  K++HE G  F R+C
Sbjct:  138 DLTVYKGKLSQHTKTPDIFTLSETSTSTYEALCRGEELNMKSRRRRQLSCRYSTGGGNPRLMYAPVKEEEVWDDPPIMTYHDVFSEAEIEQLKNLSRPGVSTALHVWLK------------------DEDAPVVSSVSQRLSDITGLG---------MESAESLQVLNYGVGGHFSPHYDTVVRKNLKSIMFPSPL----------QLSDVSYGGSTVFPEIGASVKPQKGSVVMWYNLLRNGQGDWRSLHGGCPVYQGSKWVAVKWVHERGQEFRRQC 379
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Match: EDO30487 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0N3])

HSP 1 Score: 137.117 bits (344), Expect = 1.823e-34
Identity = 126/470 (26.81%), Postives = 213/470 (45.32%), Query Frame = 3 
Query:  441 NHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDN-QFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNS-----------DLLCRE-NYNSSE-YYNLRCFYRRIKKGWDRA---KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVY--LEKGVLN-ANEKYAKE---EAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
             HP+NA   +RR + +   +       + L K +  +DL ++L    R     +PT  D+   V  I RI +VY I    I+ G + + TS  PM  D    +    +R   H +  +W E  L   +   +   + Q ++++   A + + T+ E  A+    E+++    +N    R+L+F+  +  Q K N   +  N+               + LCR  +Y S+E    LRC+Y   +    R    KVE L+ +PPI+    V+ D +I E      T K+++     L+ G L  A+ + +K    E    D +  ++  ++R+ S  TGL+T          S+   +++NYG  G+ E   D+ A         + +  G+R+AT  Y+++D   GG  VF   +  +   +G    W+NL KNG  +  + H  CP+  GSKWV  K+IHE+G  F R C
Sbjct:   79 GHPVNAYMLIRRFIKNWKDV------EEYLEKHDDQEDLLALL----RLHKVDFPTSKDMLGCVQAIQRIQDVYNITAKRIASGHLSDITSTPPMSADSCFEIGYAHHRWEKHEEARQWMEESLRRLDPPFRYRGSLQKQDILEFIAWSEYMTEREDLALAHTSELLQLDP-NNDFAARNLEFFLQEY-QAKANGSTKKPNIFKKPPPPREHFMEAYERLCRGISYRSNEEAAKLRCYYDFTRHPMFRIRPLKVEELHSDPPIWMLRDVMYDSEI-EYIKRTATPKLRRATVTNLKTGELEFADYRISKSGWLEDPRDDNEEKILNRVNRRTSIITGLDTTPR-------SAEALQIVNYGAAGHYEPHFDH-ATEAVSSILKLGI--GNRIATVLYYMSDVEAGGATVFVDAEAIVKPSKGDAAFWYNLHKNGKGDERTRHAACPIIVGSKWVCNKWIHEHGQEFRRPC 525
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Match: EDO36263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ26])

HSP 1 Score: 107.071 bits (266), Expect = 1.591e-24
Identity = 77/246 (31.30%), Postives = 126/246 (51.22%), Query Frame = 3 
Query: 1062 LCRENYNS---SEYYNLRCFYRRIKKGWDRAKV--ELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVY-LEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            LCR N  +   S    L C Y     G     V  E++++NP I  ++ VL++ +I ++  L +    +  V  LE G +   +    + A   D D D+++ ++R++   TGL TN  +           +V NYG+GG+ E   D+   +D E     S+  G+R+AT+ ++L++   GG  VF K  +     +G  + W+NL K+G  +  S H  CPV  G+KWV  K++HE+GN FTR+C
Sbjct:  285 LCRPNSQTRLPSSNKQLTCSYLNKHPGLKLKPVAMEIVSVNPQITLFHNVLSEMEIEQMLELARPRLRRARVNNLETGEIEDVDYRISQIAWLSDSDGDIVRRINRRVGFITGLNTNTGEC---------LQVNNYGVGGHYEPHFDH--SLDMENSPIASLGQGNRIATFMFYLSEVEAGGSTVFIKTGVKTNPFKGGAVFWYNLKKSGEGDWDSLHAGCPVLIGNKWVANKWLHEHGNEFTRQC 519
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Match: EDO36261 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ24])

HSP 1 Score: 105.916 bits (263), Expect = 4.189e-24
Identity = 102/499 (20.44%), Postives = 209/499 (41.88%), Query Frame = 3 
Query:  441 NHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCF--YRRIKKG-------WDRA------------------KVELLNMNPPIYKYYGVLNDEDIYEVFNL----VKTSKIKQHVYLEKGVLNANEKYAKEEAIF-------------------W--DEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
             HP+N+   ++R  FH            + ++    +D S V    + +    +P+  D+  A++ + R+ + Y++    IS G +    ++  M + +   + + +   N       W E  L   +    + D +  ++    A A +   N K+A+N  EE+++      +  +    F    ++Q K   +      + +     ++      ++  + F  Y ++ +G       W++                   ++E + + P +  +   + D +I  +  L    +K + +K  V  E  ++ AN + +K  A                     W  DE+ +++K +S ++   +GL          +++S   +V+NYGIGG+ E   D+     + + K  S+  G+R+AT+  +L+D   GG  VF +V  ++  ++G    W+NL ++G  +  + H  CPV  GSKWV  K+IHE G  F + C
Sbjct:   51 GHPVNSFALIKR--FH---------KGWSRMEELALKDTSEVFVETLTKHKDQFPSQEDVDGAITALLRLQDTYRLTPDVISTGRLPKVRAVPMMTVSDTFDIGRSAYLSNDMFYTKAWMEVALEKIKKGEDSEDVKLFDVYDHLAFAEYQRGNFKKALNYSEEMVKIDPTHTRATDNVAYFGSEIAKQTKKRGDTGTSRRTKSPSSTFKKLKEREYFHRTKAFQNYEKLCRGEVRSLTKWEQGQMSCWQIRDDPLTVLKPGRIERVFVKPEVLIFRNFITDSEIKRIKELATPRLKRATVKDPVTGE--LIFANYRISKRRATIQHPVTGKLEFANYRISKSGWLRDEEDELVKRISYRVQAYSGLN---------MTTSEDLQVVNYGIGGHYEPHYDF---ARDGEDKFTSLGTGNRIATFLSYLSDVEAGGGTVFTRVGATVWPQKGDAAFWYNLKRSGDGDSSTRHAACPVLVGSKWVANKWIHEVGQEFRKPC 524
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Match: EDO27272 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9Q1])

HSP 1 Score: 88.9669 bits (219), Expect = 6.472e-21
Identity = 50/152 (32.89%), Postives = 84/152 (55.26%), Query Frame = 3 
Query: 1326 DEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            DE+ +++K +S ++   +GL          +++S   +V+NYGIGG+ E   D+       + K  S+  G+R+AT+  +L+D   GG  VF +V  ++  ++G    W+NL ++G  +  + H  CPV  GSKWV  K+IHE G  F + C
Sbjct:    8 DEEDELVKRISYRVQAYSGLN---------MTTSEDLQVVNYGIGGHYEPHYDF------ARDKFTSLGTGNRIATFLSYLSDVEAGGGTVFTRVGATVWPQKGDAAFWYNLKRSGDGDSSTRHAACPVLVGSKWVANKWIHEVGQEFLKPC 144
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Match: EDO46235 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQV7])

HSP 1 Score: 95.5153 bits (236), Expect = 7.478e-21
Identity = 117/480 (24.38%), Postives = 201/480 (41.88%), Query Frame = 3 
Query:  420 SATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLD--EMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFR--NLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKV---ELLNMNPPIYKYYGVLNDEDIYEVFN----------LVKTSKIKQ------HVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            SA  +P +   HP+N    ++R V    P + ++   ++          + +LDR +    S +PT  DL  A++ I R+  VY +   + S+G  F        LL   +   + +ES          EW    L   +  + N     R  +++   A A F   + ++A+N   E+I+    +N   + +L F+  + ++D+ N EN                       NL  F + +K+  D +K    E    N P YK+      +D++E FN          L +  K+        H  +   +  A+ + +K   +   E  +V+  + R+I+  T L          + ++  F+V NYG+ G  +   D+    D       S+  G+R+AT    ++    GG  VFP V   +L ++G  + W NLL++G  +  + H  CPV  G KWV  K+IHE GN F R C
Sbjct:   53 SAEGSPGSYIGHPVNMYLMIKRFVNEW-PQVEKVVEEQS-------NSEAFLLDR-LASSKSKFPTSEDLTGAITAIKRLQEVYALKPVDFSEGR-FGFKPKTGYLLGPKDTYKIGRESYLDGDMVGTAEWMTETLRLMDLGVSNGAQAPRRTDVLDHLAFAEFKNGDGRKALNHTLELIKIDP-ENTRAKNNLAFFTQEMKRDE-NPENTRAK------------------NNLAFFTQEMKR--DESKFTKKEEEKKNVPSYKWMKSRLSQDVFENFNWHVERDIYKRLCRGEKLPTLNRATVHNPITGHLETAHYRISKNCWLSGREHGEVIDRVERRIAAMTRLN---------LETAEGFQVQNYGLAGQYDPHFDF--SRDLANSSLGSLGTGNRIATVLVWMSQVESGGATVFPYVGARILPQKGDAVFWHNLLRSGDGDFRTRHAGCPVLSGIKWVANKWIHEYGNEFHRPC 489
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Match: p4ha2 (prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI gene;Acc:101166436])

HSP 1 Score: 105.531 bits (262), Expect = 1.830e-23
Identity = 106/430 (24.65%), Postives = 183/430 (42.56%), Query Frame = 3 
Query:  600 WPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQES-NRKNYHSDVLEWAEFLLNNF----ESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEII-----REKLFDN-----KLLERDLKFYKSKSEQDKVNAENQNINLSNNS------------DLLCR-ENYNSSEYYNLRCFYRRIKKGWDRAKVELLNM-------NPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +P   D   A   + R+ + Y++     SKG++    S   + +D+   + + + N  +Y+  VL W +  L       E+ +   D     ++   + +++   +   AI L   ++      ++   N     +LL + LK    +S QD      + I L   +            + LCR E    +E    R F R    G    ++ L  +       NP I +Y  +L+D++I ++  L K    +  V   K GVL        + A    ED  V+  ++++I   TGL          + ++   +V NYG+GG  E   D+     +E      +  G+R+AT+  +++D   GG  VFP    S+   +GT + W+NL ++G  +  + H  CPV  GSKWV  K+IHE G  F R C
Sbjct:  121 FPDEEDQTGAAKALMRLQDTYQLDSEAFSKGMLPGVHSNAVLTVDDCFDMGKTAYNDADYYHAVL-WFQQALKQLDDGEEAAVSKAD-----ILDYLSYSVYQMGDLPRAIELTRRLVAIDPNHQRAGGNLRYFEQLLMKQLK----ESNQDYQPPSEEPIQLGTYTRPKDHLPERETYEALCRGEGLQLTEARRSRLFCR-YHDGKRSPRLLLKPIKEEDEWDNPHIVRYLNILSDQEIEKIKELAKPRLARATVRDPKTGVLTTAPYRVSKSAWLEGEDDPVIDRVNQRIQDITGLT---------VETAELLQVANYGVGGQYEPHFDF--SRKDEPDAFKRLGTGNRMATFLNYMSDVEAGGATVFPDFGASIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWIHERGQEFRRPC 528
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Match: p4ha2 (prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI gene;Acc:101166436])

HSP 1 Score: 105.531 bits (262), Expect = 1.830e-23
Identity = 106/430 (24.65%), Postives = 183/430 (42.56%), Query Frame = 3 
Query:  600 WPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQES-NRKNYHSDVLEWAEFLLNNF----ESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEII-----REKLFDN-----KLLERDLKFYKSKSEQDKVNAENQNINLSNNS------------DLLCR-ENYNSSEYYNLRCFYRRIKKGWDRAKVELLNM-------NPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEK-GVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            +P   D   A   + R+ + Y++     SKG++    S   + +D+   + + + N  +Y+  VL W +  L       E+ +   D     ++   + +++   +   AI L   ++      ++   N     +LL + LK    +S QD      + I L   +            + LCR E    +E    R F R    G    ++ L  +       NP I +Y  +L+D++I ++  L K    +  V   K GVL        + A    ED  V+  ++++I   TGL          + ++   +V NYG+GG  E   D+     +E      +  G+R+AT+  +++D   GG  VFP    S+   +GT + W+NL ++G  +  + H  CPV  GSKWV  K+IHE G  F R C
Sbjct:  121 FPDEEDQTGAAKALMRLQDTYQLDSEAFSKGMLPGVHSNAVLTVDDCFDMGKTAYNDADYYHAVL-WFQQALKQLDDGEEAAVSKAD-----ILDYLSYSVYQMGDLPRAIELTRRLVAIDPNHQRAGGNLRYFEQLLMKQLK----ESNQDYQPPSEEPIQLGTYTRPKDHLPERETYEALCRGEGLQLTEARRSRLFCR-YHDGKRSPRLLLKPIKEEDEWDNPHIVRYLNILSDQEIEKIKELAKPRLARATVRDPKTGVLTTAPYRVSKSAWLEGEDDPVIDRVNQRIQDITGLT---------VETAELLQVANYGVGGQYEPHFDF--SRKDEPDAFKRLGTGNRMATFLNYMSDVEAGGATVFPDFGASIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWIHERGQEFRRPC 528
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI gene;Acc:101163841])

HSP 1 Score: 103.219 bits (256), Expect = 9.551e-23
Identity = 108/502 (21.51%), Postives = 212/502 (42.23%), Query Frame = 3 
Query:  423 ATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKN--YHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIR-----------EKLFDNKLLERDLKFYKSKSEQDKVNAENQN----------------INLSNNSDLLCR-ENYNSSEYYNLRCFYR---------------RIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVY-LEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            AT+ P     HP+NA   M+R+      + + + +  T     F  +L+ +  +Y        PT  D   A   + R+ + Y +    IS G +      N M +++   L + +  +   YH+++  W    L   E   ++  ++   L  + + A++   + K A+   +++++           +K F+ +L +++ +   ++ E  + + E ++                I      ++LCR E    +     R F R               + +  WDR         P I +Y  ++++ ++ ++  L K    +  V+  + G L        + A     +  V++ ++++I   TGLE         + ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VFP V  S+  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  + R C
Sbjct:   72 ATQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTT---DGFISNLT-IQRQYF-------PTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTEL--WMAQALRQLEEGEESPLDKVTVLDYL-SYAIYQQGDLKRALEYTKKLLQLDPEHQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDR---------PYIVRYIDIISEAEMDKIKQLAKPRLRRATVHDPQTGKLTTAHYRVSKSAWLTAYEDPVVEKINQRIEDLTGLE---------MDTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPC 539
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI gene;Acc:101163841])

HSP 1 Score: 101.679 bits (252), Expect = 2.574e-22
Identity = 110/505 (21.78%), Postives = 212/505 (41.98%), Query Frame = 3 
Query:  423 ATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKN--YHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIR-----------EKLFDNKLLERDLKFYKSKSEQDKVNAENQN----------------INLSNNSDLLCR-ENYNSSEYYNLRCFYR---------------RIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKT----SKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            AT+ P     HP+NA   M+R+      + + + +  T     F  +L+ +  +Y        PT  D   A   + R+ + Y +    IS G +      N M +++   L + +  +   YH+++  W    L   E   ++  ++   L  + + A++   + K A+   +++++           +K F+ +L +++ +   ++ E  + + E ++                I      ++LCR E    +     R F R               + +  WDR         P I +Y  ++++ ++ ++  L K     + I   V    GVL        + A     +  V++ ++++I   TGLE         + ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VFP V  S+  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  + R C
Sbjct:   43 ATQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTT---DGFISNLT-IQRQYF-------PTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTEL--WMAQALRQLEEGEESPLDKVTVLDYL-SYAIYQQGDLKRALEYTKKLLQLDPEHQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDR---------PYIVRYIDIISEAEMDKIKQLAKPRLRRATISNPV---TGVLETAPYRISKSAWLTAYEDPVVEKINQRIEDLTGLE---------MDTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPC 510
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI gene;Acc:101163841])

HSP 1 Score: 101.679 bits (252), Expect = 3.161e-22
Identity = 110/505 (21.78%), Postives = 212/505 (41.98%), Query Frame = 3 
Query:  423 ATKTPTN---HPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKN--YHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIR-----------EKLFDNKLLERDLKFYKSKSEQDKVNAENQN----------------INLSNNSDLLCR-ENYNSSEYYNLRCFYR---------------RIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKT----SKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            AT+ P     HP+NA   M+R+      + + + +  T     F  +L+ +  +Y        PT  D   A   + R+ + Y +    IS G +      N M +++   L + +  +   YH+++  W    L   E   ++  ++   L  + + A++   + K A+   +++++           +K F+ +L +++ +   ++ E  + + E ++                I      ++LCR E    +     R F R               + +  WDR         P I +Y  ++++ ++ ++  L K     + I   V    GVL        + A     +  V++ ++++I   TGLE         + ++   +V NYG+GG  E   D+     +E      +  G+R+ATW ++++D   GG  VFP V  S+  ++GT + W+NL  +G  +  + H  CPV  G+KWV  K+IHE G  + R C
Sbjct:   72 ATQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTT---DGFISNLT-IQRQYF-------PTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTEL--WMAQALRQLEEGEESPLDKVTVLDYL-SYAIYQQGDLKRALEYTKKLLQLDPEHQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDR---------PYIVRYIDIISEAEMDKIKQLAKPRLRRATISNPV---TGVLETAPYRISKSAWLTAYEDPVVEKINQRIEDLTGLE---------MDTAEELQVANYGVGGQYEPHFDF--GRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPC 539
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Planmine SMEST
Match: SMESG000006029.1 (SMESG000006029.1)

HSP 1 Score: 1152.89 bits (2981), Expect = 0.000e+0
Identity = 569/570 (99.82%), Postives = 569/570 (99.82%), Query Frame = 3 
Query:   96 MWKLREISRLLMFVWIYNFVKCENDSLSDIINNPSGQEYFNKYGHCSVSASGLRDSYFVEGQLVKAILNGYKTLEEDRYDKRNAKDYTELDGEIRKTLEILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRKTASFF 1805
            MWKLREISRLLMFVWIYNFVKCENDSLSDIINNPSGQEYFNKYGHCSVSASGLRDSYFVEGQLVKAILNGYKTLEEDRYDKRNAKDYTELDGEIRKTLEILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVN ENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAKVDEEKKKDVSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRKTASFF
Sbjct:    1 MWKLREISRLLMFVWIYNFVKCENDSLSDIINNPSGQEYFNKYGHCSVSASGLRDSYFVEGQLVKAILNGYKTLEEDRYDKRNAKDYTELDGEIRKTLEILTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNTENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRAKVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAKVDEEKKKDVSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKCYRKTASFF 570
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Planmine SMEST
Match: SMESG000005668.1 (SMESG000005668.1)

HSP 1 Score: 110.153 bits (274), Expect = 4.285e-25
Identity = 111/469 (23.67%), Postives = 204/469 (43.50%), Query Frame = 3 
Query:  441 NHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQF--RNLVRMKAAALFNTKNEKEAINLLEEI-------IREKLFDNKLLERDLKFYKSKSEQDKVNAENQNINLSNNSD-----LLCRENYN---SSEYYNLRCFYRRIKKGWDRA---KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVY--LEKGVLNANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            ++PIN+  F R+ V      L+ +      +   F + L   +D++        P   D+  A+  + R+   Y +   ++  G I N  S   +  D+   +   + +K      ++W +  LN F+    + D     R+++   +  L +    + A+N   E+       IR++L  NK       +Y  K  ++ V   ++N   S++ D      LCR       S    NL+C Y +I   + +    KVE+    P +   + +++DE+I E    V + K+ +        G+L        + A   ++  ++   ++++I+  TGL          I  +   +V+NYGIGG+     D+     +  +    +  G+R+AT  ++++D   GG  VF +V   L  ++G+   WFNL  NG  + ++ H  CPV  GSKWV+ K+ HE G  F R C
Sbjct:   86 SNPINSYLFARKFVHDWKDKLDLV---NDFVNNKFRKILQEEIDKFQDR----LPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNK------NYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKC-YNKIPHPFYKIGPLKVEVAFSKPRLVIIHDLIHDEEI-EHIKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGL---------NIEMAEDLQVVNYGIGGHYSPHFDH---GKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 527
[Close]
BLAST of Fe2OG dioxygenase domain-containing protein vs. Planmine SMEST
Match: SMESG000060999.1 (SMESG000060999.1)

HSP 1 Score: 101.293 bits (251), Expect = 2.845e-22
Identity = 107/446 (23.99%), Postives = 198/446 (44.39%), Query Frame = 3 
Query:  549 QDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKSKSEQDKVNAENQN----------------INLSNNS----------DLLCR--ENYNSSEYYNLRCFYRRIKKGW--DRAKVELLNMNPPIYKYYGVLNDEDIYEV----FNLVKTSKIKQHVYLEKGVLN-ANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAXXXXXXXXXXSVFGGDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 1781
            ++  S+ +R I++  +  P   DL+ ++  + R+ + YKI    I+ GII  +   N +   +   +   S  K+Y   V EWA          +K+   +   L+   +   F   N ++A+ L +E  +    + +  E ++ F      Q++ N  N N                IN+  ++          + LCR      +   ++L+C Y      +     K E L   P I  Y+ ++ND +I  +     N ++ + ++  +    G L  AN + +K   +  D + ++ + ++ +I   TG+          + ++   +V+NYGIGG+ E   D+ A+  E    +  +  G+RLAT  ++++D   GG  VF K+   +  ++G    W+NLL +G  +  + H  CPV  GSKWV+ K+ HE G  FTR C
Sbjct:  101 ENFDSIANR-IQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYFV-EWASEAYYRINENVKSEKIK---LLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYF-----TQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGPIKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSI---TGKLEFANYRISKSAWLRTDVN-ELTERINLRIQLVTGIN---------LETAEELQVVNYGIGGHYEPHFDF-ARKSEINSFESEI--GNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPC 520
The following BLAST results are available for this feature:
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
P4HA27.755e-2623.86prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ... [more]
P4HA27.755e-2623.86prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ... [more]
P4HA27.755e-2623.86prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ... [more]
P4HA21.237e-2523.65prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ... [more]
P4HA21.237e-2523.65prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpy-185.186e-3225.10Prolyl 4-hydroxylase subunit alpha-1 [Source:UniP... [more]
phy-24.425e-2524.38Prolyl 4-hydroxylase subunit alpha-2 [Source:UniP... [more]
phy-45.044e-1026.87Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:... [more]
phy-41.337e-827.20Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:... [more]
Y43F8B.191.460e-629.17pep chromosome:WBcel235:V:19510780:19512164:-1 gen... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG310139.465e-3826.70gene:FBgn0051013 transcript:FBtr0085671[more]
PH4alphaPV4.686e-3123.44gene:FBgn0051015 transcript:FBtr0085670[more]
CG155392.370e-2825.99gene:FBgn0039782 transcript:FBtr0085655[more]
CG155391.292e-2724.76gene:FBgn0039782 transcript:FBtr0345121[more]
CG155391.340e-2725.99gene:FBgn0039782 transcript:FBtr0110859[more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
p4ha1b2.987e-2422.51prolyl 4-hydroxylase, alpha polypeptide I b [Sourc... [more]
p4ha1b9.879e-2422.51prolyl 4-hydroxylase, alpha polypeptide I b [Sourc... [more]
p4ha1b9.879e-2422.51prolyl 4-hydroxylase, alpha polypeptide I b [Sourc... [more]
p4ha1a1.361e-2222.57prolyl 4-hydroxylase, alpha polypeptide I a [Sourc... [more]
p4ha1a1.361e-2222.57prolyl 4-hydroxylase, alpha polypeptide I a [Sourc... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
notch35.290e-2825.36notch 3 [Source:Xenbase;Acc:XB-GENE-6450008][more]
notch38.855e-2724.90notch 3 [Source:Xenbase;Acc:XB-GENE-6450008][more]
notch31.494e-2533.17notch 3 [Source:Xenbase;Acc:XB-GENE-6450008][more]
notch39.422e-2431.71notch 3 [Source:Xenbase;Acc:XB-GENE-6450008][more]
notch32.333e-2323.70notch 3 [Source:Xenbase;Acc:XB-GENE-6450008][more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
P4ha22.480e-2526.13procollagen-proline, 2-oxoglutarate 4-dioxygenase ... [more]
P4ha22.632e-2526.37procollagen-proline, 2-oxoglutarate 4-dioxygenase ... [more]
P4ha22.632e-2526.37procollagen-proline, 2-oxoglutarate 4-dioxygenase ... [more]
P4ha12.695e-2329.76procollagen-proline, 2-oxoglutarate 4-dioxygenase ... [more]
P4ha17.940e-2329.76procollagen-proline, 2-oxoglutarate 4-dioxygenase ... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q10576|P4HA1_CAEEL6.597e-3125.10Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabd... [more]
sp|O15460|P4HA2_HUMAN5.939e-2523.65Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapie... [more]
sp|Q60716|P4HA2_MOUSE2.060e-2425.89Prolyl 4-hydroxylase subunit alpha-2 OS=Mus muscul... [more]
sp|Q20065|P4HA2_CAEEL5.629e-2424.38Prolyl 4-hydroxylase subunit alpha-2 OS=Caenorhabd... [more]
sp|P16924|P4HA1_CHICK2.843e-2230.24Prolyl 4-hydroxylase subunit alpha-1 OS=Gallus gal... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210QXI68.362e-4324.54Prolyl 4-hydroxylase subunit alpha-1 OS=Mizuhopect... [more]
R7UVX51.410e-3926.46Fe2OG dioxygenase domain-containing protein OS=Cap... [more]
K1Q8K99.771e-3926.42KRR1 small subunit processome component-like prote... [more]
K1QGQ19.372e-3826.04Prolyl 4-hydroxylase subunit alpha-1 OS=Crassostre... [more]
A0A0L8FTK81.051e-3727.65Fe2OG dioxygenase domain-containing protein OS=Oct... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
p4ha1a8.452e-2622.91prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI ... [more]
p4ha24.917e-2431.55prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI ... [more]
zgc:1526704.298e-2224.88zgc:152670 [Source:ZFIN;Acc:ZDB-GENE-060929-954][more]
p4ha1b5.306e-2228.57prolyl 4-hydroxylase subunit alpha-1-like [Source:... [more]
zgc:1526705.602e-2228.32zgc:152670 [Source:ZFIN;Acc:ZDB-GENE-060929-954][more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO304871.823e-3426.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO362631.591e-2431.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO362614.189e-2420.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO272726.472e-2132.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO462357.478e-2124.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
p4ha21.830e-2324.65prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI ... [more]
p4ha21.830e-2324.65prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI ... [more]
p4ha1b9.551e-2321.51prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI ... [more]
p4ha1b2.574e-2221.78prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI ... [more]
p4ha1b3.161e-2221.78prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI ... [more]
back to top
BLAST of Fe2OG dioxygenase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000006029.10.000e+099.82SMESG000006029.1[more]
SMESG000005668.14.285e-2523.67SMESG000005668.1[more]
SMESG000060999.12.845e-2223.99SMESG000060999.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016646 ID=SMED30016646|Name=Fe2OG dioxygenase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1896bp
CGCAATAATACTTGATTTTGTCGACAGGGATTTCATTTTTCACTTTTGCA
AAAAGCTACACGTAACCCATATTTTCCTGGCAGAGATCTCTAAACATGTG
GAAATTGAGAGAAATATCTAGGCTTTTAATGTTTGTTTGGATTTATAATT
TTGTAAAATGCGAAAATGACTCTCTCTCTGACATCATAAACAATCCATCT
GGACAAGAGTATTTCAACAAATACGGACATTGTTCGGTATCTGCAAGCGG
CCTGAGAGATTCATATTTTGTTGAAGGACAGTTAGTAAAAGCAATTCTCA
ACGGCTATAAGACTTTAGAAGAAGATAGGTATGACAAACGAAATGCTAAA
GATTATACCGAGTTGGACGGAGAGATTAGAAAAACTTTGGAAATTTTAAC
AGCTGCAAGGAGAACGGAAAGTGCAACTAAAACCCCAACAAATCATCCGA
TAAACGCTTTGCACTTCATGAGACGTATTGTATTTCATTTAAATCCGATT
TTAAACAGAATTTTCACCTCAAAAACTTTGTTGAAACGAAATTTTTATCA
AGATCTGAGTAGTGTACTCGATAGGTACATCAGGGAGGAATGCTCGTGCT
GGCCAACACCATCTGATCTTCAAGTAGCCGTTTCGGGAATAGCAAGGATA
ATCAACGTCTACAAAATCCCAAAAGCAAACATTTCAAAGGGGATTATATT
TAATCATACATCTATAAATCCAATGCTCTTGGACGAAATGATTGTCCTTG
CACAGGAATCAAACAGAAAGAACTATCATTCAGATGTTCTAGAATGGGCT
GAATTCTTACTCAATAATTTTGAATCTGAAATAAAAAATAATGACAATCA
GTTTAGAAATCTTGTCCGAATGAAAGCTGCTGCTTTATTTAATACTAAAA
ATGAAAAAGAAGCAATAAATCTATTGGAGGAAATTATTCGAGAAAAATTA
TTCGACAACAAATTGTTAGAGAGAGATTTAAAATTTTATAAAAGTAAATC
AGAACAAGATAAAGTGAATGCTGAAAACCAAAACATAAATCTTTCAAATA
ATTCTGATTTATTGTGTAGAGAAAATTATAACTCATCAGAATATTATAAT
CTACGTTGCTTTTATCGAAGAATTAAAAAAGGTTGGGATAGAGCAAAAGT
TGAACTGTTGAATATGAATCCTCCCATATATAAATATTATGGGGTATTGA
ATGATGAAGACATTTATGAAGTTTTTAATCTTGTTAAAACATCGAAAATA
AAACAGCATGTTTATCTCGAAAAAGGAGTCCTTAATGCCAATGAAAAATA
TGCCAAAGAAGAAGCAATATTTTGGGATGAAGATTATGACGTAATGAAAA
GCTTAAGTAGACAGATTTCTCATCAAACTGGGCTGGAAACAAATAATCAT
AAATACAACACACGAATTTCATCCTCAGGACCTTTTAAGGTTATTAACTA
CGGAATTGGGGGATACGAAGAACTAGAAGTGGACTATTTGGCTAAGGTCG
ACGAAGAAAAAAAGAAAGACGTTTCAGTATTTGGAGGAGACAGGCTGGCA
ACTTGGCATTATCACCTAACAGATAAAATTGAAGGTGGGCGAATAGTATT
TCCTAAAGTAAAAATGTCGCTTTTATTAGAACAAGGAACGGGTTTATTGT
GGTTTAATTTGTTGAAAAATGGAACAGTCAATCCGTTAAGTGAACATATG
GAATGTCCAGTAGCATATGGCTCAAAATGGGTTGTCAAAAAATTTATCCA
CGAAAATGGAAACATGTTCACTCGAAAATGCTATAGAAAAACTGCATCTT
TTTTTTAAAAAGACTCATTTCAAAATGAATTTTGTTCGAATTTAGGATTA
TTAATAATACAATTTTATTATTATTATGATTATTATTATTATTATT
back to top

protein sequence of SMED30016646-orf-1

>SMED30016646-orf-1 ID=SMED30016646-orf-1|Name=SMED30016646-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=571bp
MWKLREISRLLMFVWIYNFVKCENDSLSDIINNPSGQEYFNKYGHCSVSA
SGLRDSYFVEGQLVKAILNGYKTLEEDRYDKRNAKDYTELDGEIRKTLEI
LTAARRTESATKTPTNHPINALHFMRRIVFHLNPILNRIFTSKTLLKRNF
YQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGI
IFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNND
NQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKS
KSEQDKVNAENQNINLSNNSDLLCRENYNSSEYYNLRCFYRRIKKGWDRA
KVELLNMNPPIYKYYGVLNDEDIYEVFNLVKTSKIKQHVYLEKGVLNANE
KYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVI
NYGIGGYEELEVDYLAKVDEEKKKDVSVFGGDRLATWHYHLTDKIEGGRI
VFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKF
IHENGNMFTRKCYRKTASFF*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000419prepharyngeal region
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR011990TPR-like_helical_dom_sf
IPR006620Pro_4_hyd_alph
IPR013547Pro_4_hyd_alph_N
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0031418L-ascorbic acid binding
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0005506iron ion binding
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0004656procollagen-proline 4-dioxygenase activity
GO:0016491oxidoreductase activity
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0019511peptidyl-proline hydroxylation
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006620Prolyl 4-hydroxylase, alpha subunitSMARTSM00702p4hccoord: 359..552
e-value: 3.1E-9
score: 46.7
NoneNo IPR availableGENE3DG3DSA:2.60.120.620coord: 342..553
e-value: 9.4E-29
score: 102.6
NoneNo IPR availablePANTHERPTHR10869:SF154PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2coord: 102..563
NoneNo IPR availablePANTHERPTHR10869PROLYL 4-HYDROXYLASE ALPHA SUBUNITcoord: 102..563
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..22
score: 0.629
IPR013547Prolyl 4-hydroxylase alpha-subunit, N-terminalPFAMPF08336P4Ha_Ncoord: 94..201
e-value: 2.0E-9
score: 37.6
IPR011990Tetratricopeptide-like helical domain superfamilyGENE3DG3DSA:1.25.40.10coord: 173..301
e-value: 8.1E-9
score: 37.5