rRNA 2'-O-methyltransferase fibrillarin

Overview
NamerRNA 2'-O-methyltransferase fibrillarin
Smed IDSMED30016529
Length (bp)879
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of rRNA 2'-O-methyltransferase fibrillarin (SMED30016529) t-SNE clustered cells

Violin plots show distribution of expression levels for rRNA 2'-O-methyltransferase fibrillarin (SMED30016529) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of rRNA 2'-O-methyltransferase fibrillarin (SMED30016529) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for rRNA 2'-O-methyltransferase fibrillarin (SMED30016529) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016529

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30016529SMESG000074728.1 SmedASXL_006810SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30016529SMESG000074728.1 SmedASXL_006810SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Human
Match: FBL (fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599])

HSP 1 Score: 180.644 bits (457), Expect = 1.552e-55
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:    1 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 229
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Human
Match: FBL (fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599])

HSP 1 Score: 180.644 bits (457), Expect = 1.552e-55
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:    1 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 229
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Human
Match: FBL (fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599])

HSP 1 Score: 180.259 bits (456), Expect = 2.830e-54
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   86 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 314
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Human
Match: FBL (fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599])

HSP 1 Score: 180.259 bits (456), Expect = 2.830e-54
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   86 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 314
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Human
Match: FBLL1 (fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35458])

HSP 1 Score: 180.644 bits (457), Expect = 2.863e-54
Identity = 84/229 (36.68%), Postives = 144/229 (62.88%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V +E HR +G+FI +G  D L+T  +  G+++Y +R+VTVT+     +Y TWNPF+SK+AAAIL G D I+ +  SKVLY+GA++ + + H+SD+IGP G ++A+        D++  A +RTNI P++ +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ ++ + A  ID T +AE+++A ++  L+  N  P+ ++ L PY  + A++   YR
Sbjct:   98 VSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGVKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYR 326
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Celegans
Match: fib-1 (rRNA 2'-O-methyltransferase fibrillarin [Source:UniProtKB/Swiss-Prot;Acc:Q22053])

HSP 1 Score: 170.629 bits (431), Expect = 1.204e-50
Identity = 78/229 (34.06%), Postives = 143/229 (62.45%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTD-SEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR+ G+FI KG  D L T+ +  G+++Y +++V+V D + +++Y  WNPF+SK+AA+I+ G ++ + +  +K+LY+GA++ + + H SDV+GP G ++A+        D+L  A +R N+ PI+ +  HP  Y + + +VD I  D++      +++ NA+ +LR+ G+ V+ + A  ID T   E+++A ++N LK   F P  ++ L PY  + A++   YR
Sbjct:  117 VVVEPHRLGGVFIVKGKEDALATKNMVVGESVYGEKRVSVDDGAGSIEYRVWNPFRSKLAASIMGGLENTHIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLGVAKKRPNVVPIVEDARHPHKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGGHAVISIKANCIDSTAEPEAVFAGEVNKLKEEKFKPLEQVTLEPYERDHAVVVAVYR 345
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Celegans
Match: fib-1 (rRNA 2'-O-methyltransferase fibrillarin [Source:UniProtKB/Swiss-Prot;Acc:Q22053])

HSP 1 Score: 170.629 bits (431), Expect = 1.204e-50
Identity = 78/229 (34.06%), Postives = 143/229 (62.45%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTD-SEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR+ G+FI KG  D L T+ +  G+++Y +++V+V D + +++Y  WNPF+SK+AA+I+ G ++ + +  +K+LY+GA++ + + H SDV+GP G ++A+        D+L  A +R N+ PI+ +  HP  Y + + +VD I  D++      +++ NA+ +LR+ G+ V+ + A  ID T   E+++A ++N LK   F P  ++ L PY  + A++   YR
Sbjct:  117 VVVEPHRLGGVFIVKGKEDALATKNMVVGESVYGEKRVSVDDGAGSIEYRVWNPFRSKLAASIMGGLENTHIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLGVAKKRPNVVPIVEDARHPHKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGGHAVISIKANCIDSTAEPEAVFAGEVNKLKEEKFKPLEQVTLEPYERDHAVVVAVYR 345
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Fly
Match: Fib (gene:FBgn0003062 transcript:FBtr0071982)

HSP 1 Score: 179.489 bits (454), Expect = 5.356e-54
Identity = 81/229 (35.37%), Postives = 143/229 (62.45%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTV-TDSEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V IE HR +G+FI++G  D L+TR    G  +Y +++++V T+ E ++Y  WNPF+SK+AAA+L G + I+    SKVLY+GA++ + + H+SDV+GP G ++A+        D++  A +RTNI PII +  HP  Y + + +VDTI  D++      +++ NA+ +L++ G+ V+ + A  ID T   E+++A ++  +++    P+ ++ L PY  + A++   YR
Sbjct:  111 VTIEPHRHEGVFIARGKEDALVTRNFVPGSEVYGEKRISVETNGEKIEYRVWNPFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVISIKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYR 339
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Fly
Match: CG10909 (gene:FBgn0038090 transcript:FBtr0082685)

HSP 1 Score: 108.997 bits (271), Expect = 2.951e-27
Identity = 66/229 (28.82%), Postives = 115/229 (50.22%), Query Frame = 2 
Query:  155 IEAHRIQGIFISKGVID--NLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCK--NMHNDILYAANQRTNIFPIIANPLHPGTYSIQM-ILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEY 823
            IE HR  G+++ +   D   LLTR   S  + Y +R+V     E   ++  W+PF+SK+AA I+ G  D++ ++ SKVLY+GA    ++ HISD++G  G ++A+ +       +   AN+R+NI PI+ +   P  Y  ++   +D I  D+        +  NA+ +L   G+ V ++++      V  +  +A +   LK     PK  + L P+    A +   Y
Sbjct:  114 IEPHRHYGVYLLRNRFDAIQLLTRNTSSSADDYGERRVISEYREMRCEFRVWSPFQSKLAAGIMGGVSDLHLQIGSKVLYLGAGFGRSVSHISDIVGDSGMVYAVEQIPWAGRQLTIMANRRSNIVPIVEDATMPYKYRYEVPACIDIIFADLPPSVLIRALMLNARHFLNPGGHFVAYLHSPTSQGVVFNKDSFAAERRLLKEKQLEPKEMVLLEPFKAGYAFVVGVY 342
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Zebrafish
Match: fbl (fibrillarin [Source:ZFIN;Acc:ZDB-GENE-040426-1936])

HSP 1 Score: 175.252 bits (443), Expect = 1.543e-52
Identity = 80/230 (34.78%), Postives = 143/230 (62.17%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV +E HR +G+FI +G  D L+T+ +  G+++Y ++++ V + E  ++Y  WNPF+SK+AAAIL G D I+ +   KV+Y+GA++ + + H+SD++GP G ++A+        D+L  A +RTNI PII +  HP  Y + + +VD I  D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  + + N  P+ ++ L PY  + A++   YR
Sbjct:   81 KVTVEPHRHEGVFICRGKEDALVTKNMVIGESVYGEKRINVEEGETKIEYRAWNPFRSKLAAAILGGIDQIHIKPGVKVMYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLLNVAKKRTNIIPIIEDARHPHKYRMLVGMVDVIFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFASEVKKMSAENMKPQEQLTLEPYERDHAVVVGIYR 310
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Xenopus
Match: slc38a11 (solute carrier family 38 member 11 [Source:Xenbase;Acc:XB-GENE-6045807])

HSP 1 Score: 181.8 bits (460), Expect = 7.793e-55
Identity = 82/230 (35.65%), Postives = 145/230 (63.04%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV++E HR +GIFI +G  D L+T+ L  G+++Y +++++V D E   +Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SDV+GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD +  D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   89 KVIVEPHRHEGIFICRGKEDALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSKIAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPVIEDARHPHKYRMLVGMVDVVFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFAAEVKKMQQENMKPQEQLTLEPYERDHAVVVGIYR 318
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Xenopus
Match: slc38a11 (solute carrier family 38 member 11 [Source:Xenbase;Acc:XB-GENE-6045807])

HSP 1 Score: 181.415 bits (459), Expect = 9.658e-55
Identity = 82/230 (35.65%), Postives = 145/230 (63.04%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV++E HR +GIFI +G  D L+T+ L  G+++Y +++++V D E   +Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SDV+GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD +  D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   89 KVIVEPHRHEGIFICRGKEDALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSKIAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPVIEDARHPHKYRMLVGMVDVVFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFAAEVKKMQQENMKPQEQLTLEPYERDHAVVVGIYR 318
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Xenopus
Match: slc38a11 (solute carrier family 38 member 11 [Source:Xenbase;Acc:XB-GENE-6045807])

HSP 1 Score: 181.415 bits (459), Expect = 1.087e-54
Identity = 82/230 (35.65%), Postives = 146/230 (63.48%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV++E HR +GIFI +G  D L+T+ L  G+++Y +++++V D E   +Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SDV+GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD ++ D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   89 KVIVEPHRHEGIFICRGKEDALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSKIAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPVIEDARHPHKYRMLVGMVDVVLRDVAQPDQTRIVALNAHTFLKNGGHFVISIKANCIDSTAAPEAVFAAEVKKMQQENMKPQEQLTLEPYERDHAVVVGIYR 318
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Xenopus
Match: slc38a11 (solute carrier family 38 member 11 [Source:Xenbase;Acc:XB-GENE-6045807])

HSP 1 Score: 169.474 bits (428), Expect = 3.339e-50
Identity = 77/222 (34.68%), Postives = 138/222 (62.16%), Query Frame = 2 
Query:  170 IQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            + GIFI +G  D L+T+ L  G+++Y +++++V D E   +Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SDV+GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD +  D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   78 LAGIFICRGKEDALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSKIAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPVIEDARHPHKYRMLVGMVDVVFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFAAEVKKMQQENMKPQEQLTLEPYERDHAVVVGIYR 299
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Mouse
Match: Fbl (fibrillarin [Source:MGI Symbol;Acc:MGI:95486])

HSP 1 Score: 180.259 bits (456), Expect = 2.183e-54
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   92 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 320
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Mouse
Match: Fbll1 (fibrillarin-like 1 [Source:MGI Symbol;Acc:MGI:3034689])

HSP 1 Score: 177.178 bits (448), Expect = 2.856e-53
Identity = 83/229 (36.24%), Postives = 143/229 (62.45%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTD-SEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V +E HR +G+FI +G  D L+T  +  G ++Y +++VTV +  E  +Y TWNPF+SK+AAAIL G D I+ +  SKVLY+GA++ + + H+SD+IGP G ++A+        D++  A +RTNI P++ +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ ++ + A  ID T +AE+++A ++  L+  N  P+ ++ L PY  + A++   YR
Sbjct:   80 VSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVMENGEKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYR 308
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. UniProt/SwissProt
Match: sp|P22232|FBRL_XENLA (rRNA 2'-O-methyltransferase fibrillarin OS=Xenopus laevis OX=8355 GN=fbl PE=2 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 4.357e-54
Identity = 83/230 (36.09%), Postives = 144/230 (62.61%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV++E HR +GIFI +G  D L+T+ L  G+++Y +++++V D E   +Y  WNPF+SK+AAAIL G D I+ +   KVLY+GA++ + + H+SDV+GP G ++A+        D++  A +RTNI P+I +  HP  Y I + +VD +  D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   87 KVIVEPHRHEGIFICRGKEDALVTKNLVPGESVYGEKRISVEDGEVKTEYRAWNPFRSKIAAAILGGVDQIHIKPGVKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPVIEDARHPHKYRILVGMVDVVFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFAAEVKKMQQENMKPQEQLTLEPYERDHAVVVGIYR 316
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. UniProt/SwissProt
Match: sp|P22087|FBRL_HUMAN (rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2)

HSP 1 Score: 180.259 bits (456), Expect = 1.359e-53
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   86 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 314
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. UniProt/SwissProt
Match: sp|A6NHQ2|FBLL1_HUMAN (rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 OS=Homo sapiens OX=9606 GN=FBLL1 PE=3 SV=2)

HSP 1 Score: 180.644 bits (457), Expect = 1.375e-53
Identity = 84/229 (36.68%), Postives = 144/229 (62.88%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V +E HR +G+FI +G  D L+T  +  G+++Y +R+VTVT+     +Y TWNPF+SK+AAAIL G D I+ +  SKVLY+GA++ + + H+SD+IGP G ++A+        D++  A +RTNI P++ +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ ++ + A  ID T +AE+++A ++  L+  N  P+ ++ L PY  + A++   YR
Sbjct:   98 VSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGVKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYR 326
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. UniProt/SwissProt
Match: sp|P35550|FBRL_MOUSE (rRNA 2'-O-methyltransferase fibrillarin OS=Mus musculus OX=10090 GN=Fbl PE=1 SV=2)

HSP 1 Score: 180.259 bits (456), Expect = 1.527e-53
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   92 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 320
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. UniProt/SwissProt
Match: sp|P22509|FBRL_RAT (rRNA 2'-O-methyltransferase fibrillarin OS=Rattus norvegicus OX=10116 GN=Fbl PE=1 SV=2)

HSP 1 Score: 180.259 bits (456), Expect = 1.560e-53
Identity = 79/229 (34.50%), Postives = 147/229 (64.19%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSE-AVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V++E HR +G+FI +G  D L+T+ L  G+++Y +++V++++ +  ++Y  WNPF+SK+AAAIL G D I+ +  +KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI P+I +  HP  Y + + +VD I  D++      +++ NA  +LR+ G+ V+ + A  ID T +AE+++A ++  ++  N  P+ ++ L PY  + A++   YR
Sbjct:   92 VMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 320
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. TrEMBL
Match: A0A4E9FPQ2 (Fibrillarin, putative OS=Brugia malayi OX=6279 GN=Bma-fib-1 PE=3 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 1.373e-55
Identity = 90/231 (38.96%), Postives = 149/231 (64.50%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVT--DSEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV+IE HR +G+FI KG  D L TR L +G+++Y +++V++   D E V+Y  WNPF+SK+AA+IL G DDI+ +  SK+LY+GA++ + + H SD++GP G ++A+        D+L  A +R NI PI+ +  HP  Y + + +VDTI  D++      +++ NA  +L++ G++V+ + A  ID T A E+++A ++N LK   F P+ ++ L PY  + A++  EYR
Sbjct:   54 KVIIEPHRHEGVFIIKGKEDALGTRNLVTGESVYGEKRVSIENDDKEKVEYRVWNPFRSKLAASILGGLDDIHIKPGSKLLYLGAASGTTVSHCSDIVGPDGLVYAVEFSHRSGRDLLNIAKKRPNIIPIVDDARHPQKYRMLVGVVDTIFSDVAQPDQARIVAINAHHFLKNGGHVVISIKANCIDSTAAPEAVFAGEVNKLKEEKFKPREQVTLEPYERDHAVVVAEYR 284
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. TrEMBL
Match: A0A0J9XVM9 (BMA-FIB-1, isoform a OS=Brugia malayi OX=6279 GN=bma-fib-1 PE=3 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 1.373e-55
Identity = 90/231 (38.96%), Postives = 149/231 (64.50%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVT--DSEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV+IE HR +G+FI KG  D L TR L +G+++Y +++V++   D E V+Y  WNPF+SK+AA+IL G DDI+ +  SK+LY+GA++ + + H SD++GP G ++A+        D+L  A +R NI PI+ +  HP  Y + + +VDTI  D++      +++ NA  +L++ G++V+ + A  ID T A E+++A ++N LK   F P+ ++ L PY  + A++  EYR
Sbjct:   54 KVIIEPHRHEGVFIIKGKEDALGTRNLVTGESVYGEKRVSIENDDKEKVEYRVWNPFRSKLAASILGGLDDIHIKPGSKLLYLGAASGTTVSHCSDIVGPDGLVYAVEFSHRSGRDLLNIAKKRPNIIPIVDDARHPQKYRMLVGVVDTIFSDVAQPDQARIVAINAHHFLKNGGHVVISIKANCIDSTAAPEAVFAGEVNKLKEEKFKPREQVTLEPYERDHAVVVAEYR 284
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. TrEMBL
Match: A0A2K6WAD7 (Uncharacterized protein OS=Onchocerca volvulus OX=6282 PE=3 SV=1)

HSP 1 Score: 189.504 bits (480), Expect = 1.450e-55
Identity = 90/232 (38.79%), Postives = 149/232 (64.22%), Query Frame = 2 
Query:  143 NKVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVT--DSEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
             +V+IE HR +G+FI KG  D L TR L  G+++Y +++V+V   D+E V+Y  WNPF+SK+AA+IL G DDI+ +  SK+LY+GA++ + + H SD++GP G ++A+        D+L  A +R NI PI+ +  HP  Y + + +VDTI  D++      +++ NA  +L++ G++V+ + A  ID T A E+++A ++N LK   F P+ ++ L PY  + A++  EYR
Sbjct:    5 KRVIIEPHRHEGVFIVKGKEDALGTRNLVMGESVYGEKRVSVENDDNEKVEYRIWNPFRSKLAASILGGLDDIHIKPGSKLLYLGAASGTTVSHCSDIVGPDGLVYAVEFSHRSGRDLLNIAKKRPNIIPIVDDARHPQKYRMLVGVVDTIFSDVAQPDQARIVAINAHHFLKNGGHVVISIKANCIDSTAAPEAVFAGEVNKLKEEKFKPREQVTLEPYERDHAVVVAEYR 236
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. TrEMBL
Match: A0A0N5D976 (Uncharacterized protein OS=Thelazia callipaeda OX=103827 GN=TCLT_LOCUS9671 PE=3 SV=1)

HSP 1 Score: 190.274 bits (482), Expect = 1.531e-55
Identity = 93/232 (40.09%), Postives = 147/232 (63.36%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTD---SEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV+IEAHR +G+FI KG  D L TR L  G+++Y +++V+V +   SE V+Y  WNPF+SK+AAAIL G DDI+ +   K+LY+GA++ + + H SD++GP G ++A+        D+L  A +R NI PI+ +  HP  Y + +  VDTI  D++      +++ NA  YL++ G+ V+ + A  ID T A E+++A ++N LK   F P+ ++ L PY  + A++  EYR
Sbjct:   30 KVIIEAHRHEGVFIVKGKEDALGTRNLVVGESVYGEKRVSVENDEGSEKVEYRIWNPFRSKLAAAILGGLDDIHIKPGCKLLYLGAASGTTVSHCSDIVGPEGLVYAVEFSHRSGRDLLNVAKKRPNIVPIVDDARHPHKYRMLVGAVDTIFSDVAQPDQARIVALNAHHYLKNGGHAVISIKANCIDSTAAPEAVFAGEVNKLKEEKFKPREQVTLEPYERDHAVVVAEYR 261
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. TrEMBL
Match: A0A0R3RY50 (Uncharacterized protein OS=Elaeophora elaphi OX=1147741 PE=3 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 2.287e-55
Identity = 90/231 (38.96%), Postives = 147/231 (63.64%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVT--DSEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            KV+IE HR +G+FI KG  D L TR L  G+++Y +++V+V   D E V+Y  WNPF+SK+AA+IL G DDI+ +  SK+LY+GA++ + + H SD++GP G ++A+        D+L  A +R N+ PI+ +  HP  Y + + +VDTI  D++      +++ NA  +L+  G++V+ + A  ID T A E+++A ++N LK   F P+ ++ L PY  + A++  EYR
Sbjct:   36 KVIIEPHRHEGVFIVKGKEDALGTRNLVVGESVYGEKRVSVESDDKEKVEYRIWNPFRSKLAASILGGLDDIHMKPGSKLLYLGAASGTTVSHCSDIVGPDGLVYAVEFSHRSGRDLLNIAKKRPNVIPIVDDARHPQKYRMLIGVVDTIFADVAQPDQARIVAINAHHFLKSGGHVVISIKANCIDSTAAPEAVFAGEVNKLKEERFKPREQVTLEPYERDHAVVVAEYR 266
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Cavefish
Match: fbl (fibrillarin [Source:ZFIN;Acc:ZDB-GENE-040426-1936])

HSP 1 Score: 170.244 bits (430), Expect = 3.194e-50
Identity = 76/222 (34.23%), Postives = 141/222 (63.51%), Query Frame = 2 
Query:  176 GIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYRST 832
            G+FI +G  D L+T+ + +G+++Y +++++V + E+ ++Y  WNPF+SK+AAAIL G D I+ +  +KV+Y+GA++ + + H+SD++GP G ++A+        D+L  A +RTNI PII +  HP  Y + + +VD I  D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  + + N  P+ ++ L PY  + A++   YRS 
Sbjct:   91 GVFICRGKEDALVTKNMVTGESVYGEKRISVDEGESKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVMYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLLNVAKKRTNIIPIIEDARHPHKYRMLVGMVDVIFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFASEVKKMSAENMKPQEQLTLEPYERDHAVVVGIYRSA 312
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Sea Lamprey
Match: fbl (fibrillarin [Source:ZFIN;Acc:ZDB-GENE-040426-1936])

HSP 1 Score: 161.384 bits (407), Expect = 8.112e-48
Identity = 77/229 (33.62%), Postives = 137/229 (59.83%), Query Frame = 2 
Query:  149 VLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            V IE HR +G+FI++G  D L+TR +  G+++Y ++++ V + E  V+Y  WNPF+SK+AAAIL G D I+ +   KVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI PI      P + +    +VD +  D++      +++ NA  +L++ G+ V+ + A  ID T   E+++A ++  +   N  P+ ++ L PY  + A++   YR
Sbjct:   96 VTIEPHRHEGVFIARGKEDALVTRNMVPGESVYGEKRMAVEEQEQKVEYRAWNPFRSKLAAAILGGVDQIHIKPGVKVLYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLMNVAKKRTNIIPIYKLECSPISLA---GMVDVVFADVAQPDQTRIVAINAHNFLKNGGHFVISIKANCIDSTAQPEAVFAQEVKKMAQENMKPQEQLTLEPYERDHAVVVGTYR 321
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Yeast
Match: NOP1 (Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; ortholog of mammalian fibrillarin; inviability of the null mutant is functionally complemented by human FBL [Source:SGD;Acc:S000002172])

HSP 1 Score: 164.081 bits (414), Expect = 4.762e-49
Identity = 75/236 (31.78%), Postives = 141/236 (59.75%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA--------VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEY 823
            KV+IE HR  G++I++G  D L+T+ +  G+++Y +++++V +           V+Y  WNPF+SK+AA I+ G D+++     KVLY+GA++ +++ H+SDV+GP G ++A+        +++  A +R NI PII +  HP  Y + + +VD +  D++      +I+ N+  +L+D+G +V+ + A  ID TV AE+++A ++  L+     P  ++ L PY  +  ++   Y
Sbjct:   85 KVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRY 320
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Nematostella
Match: EDO39937 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8G2])

HSP 1 Score: 171.785 bits (434), Expect = 6.510e-52
Identity = 80/233 (34.33%), Postives = 141/233 (60.52%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTV---TDSEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYRS 829
            +V IE HR +G+FI++G  D L+T+ L  G+ +Y ++K++V    + E ++Y  WNPF+SK+AAAIL G D I+    SKVLY+GA++ + + H+SD++GP G ++A+        D++  A +RTNI PII +  HP  Y + + +VD I  D++      +++ NA  +L++ G+ V+ + A  ID T    +++A ++  +      P+ ++ L PY  + A++   YR+
Sbjct:   61 RVSIEPHRHEGVFIARGKEDALVTKNLVPGETVYGEKKISVDGVAEGEKIEYRVWNPFRSKLAAAILGGVDKIHMPPGSKVLYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIVPIIEDARHPHKYRMLVGMVDCIFADVAQPDQTRIVAINAHNFLKNGGHFVISIKANCIDSTAQPAAVFAGEVKKMVGEKMKPQEQLTLEPYERDHAVVVGTYRA 293
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Medaka
Match: fbl (fibrillarin [Source:NCBI gene;Acc:101169139])

HSP 1 Score: 178.333 bits (451), Expect = 1.892e-53
Identity = 81/231 (35.06%), Postives = 146/231 (63.20%), Query Frame = 2 
Query:  143 NKVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTVTDSEA-VDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
             KV+IE HR +G+FI +G  D L+T+ +  G+++Y +++++V + +  ++Y  WNPF+SK+AAAIL G D I+ +  +KV+Y+GA++ + + H+SD++GP G ++A+        D+L  A +RTNI PII +  HP  Y + + +VD I  D++      +++ NA  +L++ G+ V+ + A  ID T A E+++A ++  + S N  P+ ++ L PY  + A++   YR
Sbjct:  111 KKVVIEPHRHEGVFICRGKEDALVTKNMVVGESVYGEKRMSVEEGDTKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVMYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLLNVAKKRTNIIPIIEDARHPHKYRMLVGMVDVIFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAAPEAVFASEVKKMSSENMKPQEQLTLEPYERDHAVVVGIYR 341
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Planmine SMEST
Match: SMESG000074728.1 (SMESG000074728.1)

HSP 1 Score: 354.369 bits (908), Expect = 6.482e-125
Identity = 170/171 (99.42%), Postives = 171/171 (100.00%), Query Frame = 2 
Query:  320 MAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYRST 832
            MAAAIL+GADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYRST
Sbjct:    1 MAAAILSGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYRST 171
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Planmine SMEST
Match: SMESG000074728.1 (SMESG000074728.1)

HSP 1 Score: 348.977 bits (894), Expect = 9.308e-123
Identity = 168/169 (99.41%), Postives = 169/169 (100.00%), Query Frame = 2 
Query:  320 MAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 826
            MAAAIL+GADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR
Sbjct:    1 MAAAILSGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEYR 169
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Planmine SMEST
Match: SMESG000051648.1 (SMESG000051648.1)

HSP 1 Score: 157.532 bits (397), Expect = 3.480e-46
Identity = 79/229 (34.50%), Postives = 137/229 (59.83%), Query Frame = 2 
Query:  146 KVLIEAHRIQGIFISKGVIDNLLTRQLESGKNLYDDRKVTV-TDSEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEY 823
            K ++E HR  G+F  +G  + LLT+    G ++Y ++++ +    + V+Y TWNPF+SK+AA+ILNG DDI+  + SKVLY+GAS  +++ H+SD++GP G ++A+   + +  ++L  A +RTNI PI+ +  HP  Y + +  VDTI  D++      +++ NA  +L+  G  V+ + A  ID T   E+ +  + + +    F PKS + + PY  +  +L  +Y
Sbjct:   58 KQIVE-HRHPGVFYVQGKDETLLTKNFVPGVSVYGEKRIAIGMGDDKVEYRTWNPFRSKLAASILNGIDDIHMPIGSKVLYLGASTGTSVSHVSDIVGPTGVVYAVEFAERVGREMLNVAKKRTNIVPIVEDARHPYKYRMMINQVDTIFADVAQPDQSRIVAVNADFFLKPGGYAVISLKASCIDSTAEPENAFLSEKDVISKLKFKPKSWLSMEPYERDHKVLVAQY 285
[Close]
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Planmine SMEST
Match: SMESG000027841.1 (SMESG000027841.1)

HSP 1 Score: 138.658 bits (348), Expect = 9.948e-39
Identity = 72/213 (33.80%), Postives = 123/213 (57.75%), Query Frame = 2 
Query:  203 DNLLTRQLESGKNLYDDRKVTVTD----SEAVDYYTWNPFKSKMAAAILNGADDIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFAL--CKNMHNDILYAANQRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLRDRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTNCAMLTFEY 823
            + +LT+ L +G+ +Y ++KV V D     + V+Y  WNP++SK+ AAI  G D++Y    SKVLY+GA+N + + H+SD++GP G ++A+   K    D+   +  R NI PII +   P  Y + +  VD I  D++      +++ NA+ +L+  G +VL + A  +D +   ES+Y  +I+ LK  N  P S++ L  +    A++T +Y
Sbjct:   96 NEILTKNLTNGETVYGEKKVQVPDETEPGKKVEYRVWNPYRSKIGAAITLGIDNVYINEGSKVLYLGAANGTTVSHVSDMVGPKGIVYAVEFSKRSGRDLENMSTNRPNIIPIIHDARVPAIYRLIVGSVDMIFADVAQPDQSRIVAMNAEMFLKKGGYVVLSIKAACVDSSANPESVYLSEIDTLKKLNIKPLSQLDLGDFSRGHAVVTGQY 308
The following BLAST results are available for this feature:
BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FBL1.552e-5534.50fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599][more]
FBL1.552e-5534.50fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599][more]
FBL2.830e-5434.50fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599][more]
FBL2.830e-5434.50fibrillarin [Source:HGNC Symbol;Acc:HGNC:3599][more]
FBLL12.863e-5436.68fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
fib-11.204e-5034.06rRNA 2'-O-methyltransferase fibrillarin [Source:U... [more]
fib-11.204e-5034.06rRNA 2'-O-methyltransferase fibrillarin [Source:U... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Fib5.356e-5435.37gene:FBgn0003062 transcript:FBtr0071982[more]
CG109092.951e-2728.82gene:FBgn0038090 transcript:FBtr0082685[more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fbl1.543e-5234.78fibrillarin [Source:ZFIN;Acc:ZDB-GENE-040426-1936][more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
slc38a117.793e-5535.65solute carrier family 38 member 11 [Source:Xenbase... [more]
slc38a119.658e-5535.65solute carrier family 38 member 11 [Source:Xenbase... [more]
slc38a111.087e-5435.65solute carrier family 38 member 11 [Source:Xenbase... [more]
slc38a113.339e-5034.68solute carrier family 38 member 11 [Source:Xenbase... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Fbl2.183e-5434.50fibrillarin [Source:MGI Symbol;Acc:MGI:95486][more]
Fbll12.856e-5336.24fibrillarin-like 1 [Source:MGI Symbol;Acc:MGI:3034... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P22232|FBRL_XENLA4.357e-5436.09rRNA 2'-O-methyltransferase fibrillarin OS=Xenopus... [more]
sp|P22087|FBRL_HUMAN1.359e-5334.50rRNA 2'-O-methyltransferase fibrillarin OS=Homo sa... [more]
sp|A6NHQ2|FBLL1_HUMAN1.375e-5336.68rRNA/tRNA 2'-O-methyltransferase fibrillarin-like ... [more]
sp|P35550|FBRL_MOUSE1.527e-5334.50rRNA 2'-O-methyltransferase fibrillarin OS=Mus mus... [more]
sp|P22509|FBRL_RAT1.560e-5334.50rRNA 2'-O-methyltransferase fibrillarin OS=Rattus ... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E9FPQ21.373e-5538.96Fibrillarin, putative OS=Brugia malayi OX=6279 GN=... [more]
A0A0J9XVM91.373e-5538.96BMA-FIB-1, isoform a OS=Brugia malayi OX=6279 GN=b... [more]
A0A2K6WAD71.450e-5538.79Uncharacterized protein OS=Onchocerca volvulus OX=... [more]
A0A0N5D9761.531e-5540.09Uncharacterized protein OS=Thelazia callipaeda OX=... [more]
A0A0R3RY502.287e-5538.96Uncharacterized protein OS=Elaeophora elaphi OX=11... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fbl3.194e-5034.23fibrillarin [Source:ZFIN;Acc:ZDB-GENE-040426-1936][more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fbl8.112e-4833.62fibrillarin [Source:ZFIN;Acc:ZDB-GENE-040426-1936][more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
NOP14.762e-4931.78Histone glutamine methyltransferase, modifies H2A ... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO399376.510e-5234.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fbl1.892e-5335.06fibrillarin [Source:NCBI gene;Acc:101169139][more]
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BLAST of rRNA 2'-O-methyltransferase fibrillarin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000074728.16.482e-12599.42SMESG000074728.1[more]
SMESG000074728.19.308e-12399.41SMESG000074728.1[more]
SMESG000051648.13.480e-4634.50SMESG000051648.1[more]
SMESG000027841.19.948e-3933.80SMESG000027841.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016529 ID=SMED30016529|Name=rRNA 2'-O-methyltransferase fibrillarin|organism=Schmidtea mediterranea sexual|type=transcript|length=879bp
ATTTAATTTAATGAATTTTGTTTAAATAATTTCTATTTTTTTGAATAACA
TGAGAAAGCCAAATTTTACAAGTAGTAATAGATATCTGCGAAATGAAAAA
GCAAAAAATCAAAAAAAGTTAAAAATTAATAAGGTTATAACCAATAAAGT
TTTAATTGAAGCACATCGAATTCAAGGAATTTTTATTAGTAAAGGTGTAA
TCGATAATTTACTTACGAGACAGTTGGAAAGTGGAAAAAATTTGTATGAC
GACAGGAAAGTAACCGTGACCGATAGTGAAGCAGTCGACTATTATACATG
GAATCCGTTTAAATCAAAAATGGCTGCTGCAATTTTAAATGGAGCTGATG
ATATATACTTCAGATTAAATTCTAAAGTTCTGTATATTGGTGCTAGTAAC
TGCTCTAATTTATGCCATATTTCCGATGTTATTGGTCCTGGCGGATTTTT
GTTTGCATTGTGCAAAAATATGCATAATGATATTTTATACGCTGCAAATC
AACGAACTAATATTTTTCCAATTATTGCAAACCCATTACATCCTGGAACT
TATTCAATTCAAATGATACTGGTTGACACAATTATCTGCGACATTTCATC
TTTTACAACACCTGAAATGATTTCAGAAAATGCTAAACGTTACTTACGAG
ACAGGGGCAATTTAGTTTTATTTGTCAATGCAGAAAAAATTGATAAAACT
GTTGCTGCAGAAAGTTTATATGCGTTACAAATCAACAATTTAAAATCGTT
CAATTTTGTTCCAAAATCAAAAATTTATTTGCACCCATATTTTACTAATT
GTGCTATGCTGACATTTGAATATAGATCTACAAAATCAATGAAAAAGAAT
AATTCTAAAAAATAAAAAATTTTCTTTTG
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protein sequence of SMED30016529-orf-1

>SMED30016529-orf-1 ID=SMED30016529-orf-1|Name=SMED30016529-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=272bp
MRKPNFTSSNRYLRNEKAKNQKKLKINKVITNKVLIEAHRIQGIFISKGV
IDNLLTRQLESGKNLYDDRKVTVTDSEAVDYYTWNPFKSKMAAAILNGAD
DIYFRLNSKVLYIGASNCSNLCHISDVIGPGGFLFALCKNMHNDILYAAN
QRTNIFPIIANPLHPGTYSIQMILVDTIICDISSFTTPEMISENAKRYLR
DRGNLVLFVNAEKIDKTVAAESLYALQINNLKSFNFVPKSKIYLHPYFTN
CAMLTFEYRSTKSMKKNNSKK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0031167rRNA methylation
GO:0008033tRNA processing
GO:0006364rRNA processing
GO:0032259methylation
GO:1990258histone glutamine methylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR000692Fibrillarin
IPR029063SAM-dependent_MTases
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0008168methyltransferase activity
GO:0016740transferase activity
GO:1990259histone-glutamine methyltransferase activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005730nucleolus
GO:0030529intracellular ribonucleoprotein complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000692FibrillarinPRINTSPR00052FIBRILLARINcoord: 54..73
score: 27.86
coord: 155..184
score: 30.0
coord: 80..99
score: 55.71
coord: 185..214
score: 24.52
coord: 237..258
score: 20.45
coord: 107..128
score: 42.21
IPR000692FibrillarinSMARTSM01206Fibrillarin_2coord: 36..260
e-value: 6.5E-31
score: 118.7
IPR000692FibrillarinPFAMPF01269Fibrillarincoord: 37..259
e-value: 4.0E-49
score: 166.8
NoneNo IPR availableGENE3DG3DSA:3.40.50.150coord: 85..260
e-value: 6.1E-39
score: 135.2
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 31..84
e-value: 3.4E-9
score: 38.5
NoneNo IPR availablePANTHERPTHR10335RRNA 2-O-METHYLTRANSFERASE FIBRILLARINcoord: 11..261
NoneNo IPR availablePANTHERPTHR10335:SF6RRNA/TRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN-LIKE PROTEIN 1coord: 11..261
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILYSSF53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 36..224