HAP1 N-terminal domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30016387 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Human
Match: TRAK1 (trafficking kinesin protein 1 [Source:HGNC Symbol;Acc:HGNC:29947]) HSP 1 Score: 160.614 bits (405), Expect = 1.961e-39 Identity = 129/412 (31.31%), Postives = 206/412 (50.00%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K + + S+ SLA E E T RK+ + E +S I RV E R IN
Sbjct: 39 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS--RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNIN 410
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Human
Match: TRAK1 (trafficking kinesin protein 1 [Source:HGNC Symbol;Acc:HGNC:29947]) HSP 1 Score: 160.229 bits (404), Expect = 3.259e-39 Identity = 129/412 (31.31%), Postives = 206/412 (50.00%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K + + S+ SLA E E T RK+ + E +S I RV E R IN
Sbjct: 67 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS--RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNIN 438
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Human
Match: TRAK2 (trafficking kinesin protein 2 [Source:HGNC Symbol;Acc:HGNC:13206]) HSP 1 Score: 129.028 bits (323), Expect = 1.566e-29 Identity = 111/406 (27.34%), Postives = 200/406 (49.26%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITE-LTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTI 1298
EVEL+SL+ E LP+YRLK D Y++ D+ ++ + ++ ++ L+ ++T Y +L RV +MT+TY D + L+ E+ ++ AA IG LL+RN L ++ ++E+QL + D + NQ +E D L +S A E + S + + FSL++ L+ + K E + + LR + ++ + + KEQQL+ DCV++L ++ + R+T +L+ K+++ + EE+S LL+ +DL++K+ + E + L L+ + Q LT EL +L+DR EC+ +L+E Q++I++L + + +S G+SLA E E T RK + E+S + Q + +
Sbjct: 39 PEVELVSLLEEQLPQYRLKVDT---LFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQV---------------------------NQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNES---FSLSQGLLQLEMLQEKLKELEEENMA-----LRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGP--TAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRV 404
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Human
Match: TRAK1 (trafficking kinesin protein 1 [Source:HGNC Symbol;Acc:HGNC:29947]) HSP 1 Score: 116.316 bits (290), Expect = 3.923e-26 Identity = 100/352 (28.41%), Postives = 167/352 (47.44%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQ-----SRAIRVMEQARTIN 1301
+LC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K + + S+ SLA E E T RK+ + E + RV E R IN
Sbjct: 22 VLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESS---SSVQNYFHLDSLQKKLKDLEEENVV-----LRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS--RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNIN 336
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Human
Match: TRAK1 (trafficking kinesin protein 1 [Source:HGNC Symbol;Acc:HGNC:29947]) HSP 1 Score: 116.701 bits (291), Expect = 4.901e-26 Identity = 102/352 (28.98%), Postives = 169/352 (48.01%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
+LC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K + + S+ SLA E E T RK+ + E +S I RV E R IN
Sbjct: 22 VLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS--RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNIN 336
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Fly
Match: milt (gene:FBgn0262872 transcript:FBtr0306228) HSP 1 Score: 87.8113 bits (216), Expect = 3.829e-17 Identity = 51/125 (40.80%), Postives = 73/125 (58.40%), Query Frame = 3
Query: 87 EVELISLVYENLPRYRLKADCNIQFSGYQHSD-FIRAEN--IIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKD 452
EVE+ SL+ E +P+Y+++ D FSGY + D F+ A I LT Q ++ L YFLLCG RVS+MT Y+D A+ L+EE++ ++ IG LL +N LE R+ +E L AS D
Sbjct: 68 EVEIFSLLEEQIPKYKVRNDFLTNFSGYANEDWFVPAPALPIPPEGLGLTKEQTRECLNYFLLCGNRVSQMTRAYDDIEAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASND 192 HSP 2 Score: 67.3958 bits (163), Expect = 7.174e-11 Identity = 44/151 (29.14%), Postives = 77/151 (50.99%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQ-IQGFRSVSPDIGQSL 1208
L+ + T L D ++ E+QL+ D QL D+ D L+ +L ++ + QHE+I L + E ++H+L +ND +S L + Q L EL + + RY+E + LL+ QDQ++Q K+ + + + G + +G SL
Sbjct: 249 LKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSL 399 HSP 3 Score: 51.9878 bits (123), Expect = 4.165e-6 Identity = 23/50 (46.00%), Postives = 34/50 (68.00%), Query Frame = 3
Query: 1653 YKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
+++P+KLQ++KP+EGSQTL W LATP+++ L E V RG + L
Sbjct: 637 WRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDER--PGVTIRGGRGL 684
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Fly
Match: milt (gene:FBgn0262872 transcript:FBtr0306229) HSP 1 Score: 87.8113 bits (216), Expect = 3.829e-17 Identity = 51/125 (40.80%), Postives = 73/125 (58.40%), Query Frame = 3
Query: 87 EVELISLVYENLPRYRLKADCNIQFSGYQHSD-FIRAEN--IIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKD 452
EVE+ SL+ E +P+Y+++ D FSGY + D F+ A I LT Q ++ L YFLLCG RVS+MT Y+D A+ L+EE++ ++ IG LL +N LE R+ +E L AS D
Sbjct: 68 EVEIFSLLEEQIPKYKVRNDFLTNFSGYANEDWFVPAPALPIPPEGLGLTKEQTRECLNYFLLCGNRVSQMTRAYDDIEAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASND 192 HSP 2 Score: 67.3958 bits (163), Expect = 7.174e-11 Identity = 44/151 (29.14%), Postives = 77/151 (50.99%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQ-IQGFRSVSPDIGQSL 1208
L+ + T L D ++ E+QL+ D QL D+ D L+ +L ++ + QHE+I L + E ++H+L +ND +S L + Q L EL + + RY+E + LL+ QDQ++Q K+ + + + G + +G SL
Sbjct: 249 LKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSL 399 HSP 3 Score: 51.9878 bits (123), Expect = 4.165e-6 Identity = 23/50 (46.00%), Postives = 34/50 (68.00%), Query Frame = 3
Query: 1653 YKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
+++P+KLQ++KP+EGSQTL W LATP+++ L E V RG + L
Sbjct: 637 WRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDER--PGVTIRGGRGL 684
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Fly
Match: milt (gene:FBgn0262872 transcript:FBtr0306230) HSP 1 Score: 67.3958 bits (163), Expect = 6.888e-11 Identity = 44/151 (29.14%), Postives = 77/151 (50.99%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQ-IQGFRSVSPDIGQSL 1208
L+ + T L D ++ E+QL+ D QL D+ D L+ +L ++ + QHE+I L + E ++H+L +ND +S L + Q L EL + + RY+E + LL+ QDQ++Q K+ + + + G + +G SL
Sbjct: 255 LKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSL 405 HSP 2 Score: 52.7582 bits (125), Expect = 2.324e-6 Identity = 23/50 (46.00%), Postives = 34/50 (68.00%), Query Frame = 3
Query: 1653 YKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
+++P+KLQ++KP+EGSQTL W LATP+++ L E V RG + L
Sbjct: 643 WRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDER--PGVTIRGGRGL 690 HSP 3 Score: 50.8322 bits (120), Expect = 8.282e-6 Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKD 452
+LCG RVS+MT Y+D A+ L+EE++ ++ IG LL +N LE R+ +E L AS D
Sbjct: 135 VLCGNRVSQMTRAYDDIEAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASND 198
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Fly
Match: milt (gene:FBgn0262872 transcript:FBtr0306231) HSP 1 Score: 67.3958 bits (163), Expect = 7.374e-11 Identity = 44/151 (29.14%), Postives = 77/151 (50.99%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQ-IQGFRSVSPDIGQSL 1208
L+ + T L D ++ E+QL+ D QL D+ D L+ +L ++ + QHE+I L + E ++H+L +ND +S L + Q L EL + + RY+E + LL+ QDQ++Q K+ + + + G + +G SL
Sbjct: 389 LKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSL 539 HSP 2 Score: 52.373 bits (124), Expect = 3.228e-6 Identity = 23/50 (46.00%), Postives = 34/50 (68.00%), Query Frame = 3
Query: 1653 YKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
+++P+KLQ++KP+EGSQTL W LATP+++ L E V RG + L
Sbjct: 777 WRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDER--PGVTIRGGRGL 824 HSP 3 Score: 51.2174 bits (121), Expect = 6.627e-6 Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 3
Query: 237 IQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKD 452
++ L +LCG RVS+MT Y+D A+ L+EE++ ++ IG LL +N LE R+ +E L AS D
Sbjct: 261 VRSLLTNKVLCGNRVSQMTRAYDDIEAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASND 332
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Fly
Match: milt (gene:FBgn0262872 transcript:FBtr0306233) HSP 1 Score: 67.3958 bits (163), Expect = 7.374e-11 Identity = 44/151 (29.14%), Postives = 77/151 (50.99%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQ-IQGFRSVSPDIGQSL 1208
L+ + T L D ++ E+QL+ D QL D+ D L+ +L ++ + QHE+I L + E ++H+L +ND +S L + Q L EL + + RY+E + LL+ QDQ++Q K+ + + + G + +G SL
Sbjct: 389 LKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSL 539 HSP 2 Score: 52.373 bits (124), Expect = 3.228e-6 Identity = 23/50 (46.00%), Postives = 34/50 (68.00%), Query Frame = 3
Query: 1653 YKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
+++P+KLQ++KP+EGSQTL W LATP+++ L E V RG + L
Sbjct: 777 WRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDER--PGVTIRGGRGL 824 HSP 3 Score: 51.2174 bits (121), Expect = 6.627e-6 Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 3
Query: 237 IQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKD 452
++ L +LCG RVS+MT Y+D A+ L+EE++ ++ IG LL +N LE R+ +E L AS D
Sbjct: 261 VRSLLTNKVLCGNRVSQMTRAYDDIEAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASND 332
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Zebrafish
Match: trak2 (trafficking protein, kinesin binding 2 [Source:ZFIN;Acc:ZDB-GENE-030131-7496]) HSP 1 Score: 127.487 bits (319), Expect = 2.789e-29 Identity = 147/548 (26.82%), Postives = 243/548 (44.34%), Query Frame = 3
Query: 240 QKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQ-------SRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRR--MYRNNTGDINTSFLDSQIEEASANTVASYCALEAFR-HRQNRCQTIRSLNTNILNSDSQSLHPQNIYK-----------------MPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
++T Y +L RV +MT+TY D + L+ E+ ++ AA IG +LLQRN L++R ++E+QL+ + D + QL+H+L KD+LLR++ + EE+E T + C+ A +E S + + L E N +L R + +L + KEQQL++DCV++L +S + LT +L++K D + EEI++LL+ ++L++++ L E + L L+ + Q LT EL +L DR EC+ +L+E Q++I+ L K + + P S+A E E T R++ + E+ S RV + R++N Q ++ S I T V P Q + + ED + R G S L S + S C + F+ R+ + Q + + + S S + +P+KLQ+VKP+EGS TL WQ LA P + L + V +G +PL
Sbjct: 65 EETFRYMILSADRVEQMTKTYNDIDVVTHLLSERDRDLELAARIGQSLLQRNHVLQERNESLEEQLAQALDQVHQLQHELAKKDELLRMVASASEESE----TDSSCSTPLRHPVPAGAALALSQLEALQSKLQD---------LEEENLTL----------------------RSEACHLKKETITYEEKEQQLVNDCVKELRESNSQMVSLTDELSQKNEDLMRHQEEIAQLLSQIVELQHRVKELALEKEELRIHLQASKEAQRQLTNELKELSDRNAECVGMLHESQEEIKDLRSKNTPSAGLRRHTSYGLYP--MDSIAAEIEGTMRREMSVEEEIAFEDQRSSQKRVFQTVRSVN---QSVMRAAAAGPPIPGSGVIMTPV--PYQSHT------HNTADEDASRGRENSRLGQPGSPGGSALTSALNRLSLRRQNFLCERQFFQAERERKLQDLTAAESEGGASGCSSPMGSTVSSFTNLSEFSISSSCFKTFLPEKLQIVKPMEGSLTLHHWQQLAKPHLATIL--DPHPGVVTKGFRPL 562
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Zebrafish
Match: trak2 (trafficking protein, kinesin binding 2 [Source:ZFIN;Acc:ZDB-GENE-030131-7496]) HSP 1 Score: 121.709 bits (304), Expect = 1.863e-27 Identity = 145/541 (26.80%), Postives = 239/541 (44.18%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQ-------SRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRR--MYRNNTGDINTSFLDSQIEEASANTVASYCALEAFR-HRQNRCQTIRSLNTNILNSDSQSLHPQNIYK-----------------MPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
+L RV +MT+TY D + L+ E+ ++ AA IG +LLQRN L++R ++E+QL+ + D + QL+H+L KD+LLR++ + EE+E T + C+ A +E S + + L E N +L R + +L + KEQQL++DCV++L +S + LT +L++K D + EEI++LL+ ++L++++ L E + L L+ + Q LT EL +L DR EC+ +L+E Q++I+ L K + + P S+A E E T R++ + E+ S RV + R++N Q ++ S I T V P Q + + ED + R G S L S + S C + F+ R+ + Q + + + S S + +P+KLQ+VKP+EGS TL WQ LA P + L + V +G +PL
Sbjct: 38 VLSADRVEQMTKTYNDIDVVTHLLSERDRDLELAARIGQSLLQRNHVLQERNESLEEQLAQALDQVHQLQHELAKKDELLRMVASASEESE----TDSSCSTPLRHPVPAGAALALSQLEALQSKLQD---------LEEENLTL----------------------RSEACHLKKETITYEEKEQQLVNDCVKELRESNSQMVSLTDELSQKNEDLMRHQEEIAQLLSQIVELQHRVKELALEKEELRIHLQASKEAQRQLTNELKELSDRNAECVGMLHESQEEIKDLRSKNTPSAGLRRHTSYGLYP--MDSIAAEIEGTMRREMSVEEEIAFEDQRSSQKRVFQTVRSVN---QSVMRAAAAGPPIPGSGVIMTPV--PYQSHT------HNTADEDASRGRENSRLGQPGSPGGSALTSALNRLSLRRQNFLCERQFFQAERERKLQDLTAAESEGGASGCSSPMGSTVSSFTNLSEFSISSSCFKTFLPEKLQIVKPMEGSLTLHHWQQLAKPHLATIL--DPHPGVVTKGFRPL 528
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Zebrafish
Match: trak2 (trafficking protein, kinesin binding 2 [Source:ZFIN;Acc:ZDB-GENE-030131-7496]) HSP 1 Score: 121.324 bits (303), Expect = 2.263e-27 Identity = 145/541 (26.80%), Postives = 239/541 (44.18%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQ-------SRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRR--MYRNNTGDINTSFLDSQIEEASANTVASYCALEAFR-HRQNRCQTIRSLNTNILNSDSQSLHPQNIYK-----------------MPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPL 1802
+L RV +MT+TY D + L+ E+ ++ AA IG +LLQRN L++R ++E+QL+ + D + QL+H+L KD+LLR++ + EE+E T + C+ A +E S + + L E N +L R + +L + KEQQL++DCV++L +S + LT +L++K D + EEI++LL+ ++L++++ L E + L L+ + Q LT EL +L DR EC+ +L+E Q++I+ L K + + P S+A E E T R++ + E+ S RV + R++N Q ++ S I T V P Q + + ED + R G S L S + S C + F+ R+ + Q + + + S S + +P+KLQ+VKP+EGS TL WQ LA P + L + V +G +PL
Sbjct: 91 VLSADRVEQMTKTYNDIDVVTHLLSERDRDLELAARIGQSLLQRNHVLQERNESLEEQLAQALDQVHQLQHELAKKDELLRMVASASEESE----TDSSCSTPLRHPVPAGAALALSQLEALQSKLQD---------LEEENLTL----------------------RSEACHLKKETITYEEKEQQLVNDCVKELRESNSQMVSLTDELSQKNEDLMRHQEEIAQLLSQIVELQHRVKELALEKEELRIHLQASKEAQRQLTNELKELSDRNAECVGMLHESQEEIKDLRSKNTPSAGLRRHTSYGLYPM--DSIAAEIEGTMRREMSVEEEIAFEDQRSSQKRVFQTVRSVN---QSVMRAAAAGPPIPGSGVIMTPV--PYQSHT------HNTADEDASRGRENSRLGQPGSPGGSALTSALNRLSLRRQNFLCERQFFQAERERKLQDLTAAESEGGASGCSSPMGSTVSSFTNLSEFSISSSCFKTFLPEKLQIVKPMEGSLTLHHWQQLAKPHLATIL--DPHPGVVTKGFRPL 581
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Zebrafish
Match: trak1a (trafficking protein, kinesin binding 1a [Source:ZFIN;Acc:ZDB-GENE-100922-182]) HSP 1 Score: 116.701 bits (291), Expect = 2.654e-26 Identity = 105/356 (29.49%), Postives = 169/356 (47.47%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNF-SLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK-----DTIIAEQS-RAIRVMEQARTINSS 1307
+LC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R T +E+QL ++ +S Q ++ + D L + + A E + E + D S T N+ LD + K + + + LR + +L + + KEQQL++DCV++L D+ + + +L KKT D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L D+Y EC+ +L+E Q++++ N + K + + F S+ SLA E E T RK D + EQ + RV E R +N S
Sbjct: 22 VLCADRVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKSLTERNTFLEEQLEHIREEVS---------------------------QLRHDLLMKDELLQFYTSAAEESDGESASTTPIHRND----TSFTVPNYLPLDSLQKKLKDLEEENIV-----LRSEANHLETETISYEEKEQQLVNDCVKELRDANIQISTIAEELAKKTEDASRQQEEITHLLSQIVDLQKKAKSYALENEELTQHLGAAKDAQRALTAELRELEDKYAECMEMLHEAQEELK--NFRNKTVPLSTPRRFHSLGLFPMDSLAAEIEGTMRKEIQMSDPDVEEQRLQPKRVFETVRNVNQS 339
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Zebrafish
Match: trak1a (trafficking protein, kinesin binding 1a [Source:ZFIN;Acc:ZDB-GENE-100922-182]) HSP 1 Score: 107.071 bits (266), Expect = 4.771e-23 Identity = 101/347 (29.11%), Postives = 163/347 (46.97%), Query Frame = 3
Query: 288 MTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNF-SLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK-----DTIIAEQS-RAIRVMEQARTINSS 1307
MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R T +E+QL ++ +S Q ++ + D L + + A E + E + D S T N+ LD + K + + + LR + +L + + KEQQL++DCV++L D+ + + +L KKT D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L D+Y EC+ +L+E Q++++ N + K + + F S+ SLA E E T RK D + EQ + RV E R +N S
Sbjct: 1 MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKSLTERNTFLEEQLEHIREEVS---------------------------QLRHDLLMKDELLQFYTSAAEESDGESASTTPIHRND----TSFTVPNYLPLDSLQKKLKDLEEENIV-----LRSEANHLETETISYEEKEQQLVNDCVKELRDANIQISTIAEELAKKTEDASRQQEEITHLLSQIVDLQKKAKSYALENEELTQHLGAAKDAQRALTAELRELEDKYAECMEMLHEAQEELK--NFRNKTVPLSTPRRFHSLGLFPMDSLAAEIEGTMRKEIQMSDPDVEEQRLQPKRVFETVRNVNQS 309
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Xenopus
Match: TRAK1 (trafficking protein, kinesin binding 1 [Source:NCBI gene;Acc:100135152]) HSP 1 Score: 181.03 bits (458), Expect = 4.392e-46 Identity = 159/560 (28.39%), Postives = 266/560 (47.50%), Query Frame = 3
Query: 87 EVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPS--GGNYLL-RKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAFRHRQNRCQTIRSLNTNILNSDSQSLHPQNIYKMPDKLQLVKPIEGSQTLRTWQNLATPSITKAL 1754
EVE+ISL+ E LP Y+L+AD GY H D+++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ K+ +S Q +E ++ D L + + A E E S + + S ++ F D + K + + + LR + +L + + KEQQL++DCV++L D+ + ++ +L KKT+D Q EEI+ LL+ +D++ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K ++ + V P SLA E E + RK+ M++ + + + D+ T S +++E L+ S NY+L RK ++D E++ G+I++ S S ++ ++ L F + RS +P+KLQ+VKP+EGS TL WQ LA P++ L
Sbjct: 11 EVEIISLLEEQLPHYKLRADT---IYGYDHDDWLQTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKALTERNEYLEEQVEHIKEEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESICSTPLKRNES---ASSVQNYFHFDSLQKKLKDLEDENIV-----LRSEACHLKTETITYEEKEQQLVNDCVKELRDANVQIVSISEELAKKTDDAARQQEEITHLLSQIVDIQKKAKAYAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNVISRRYHTLGVFP--LDSLAAEIEGSMRKEL----------QMDEPDSPEMNLSNGDKNKKPGTPGTPGS---SDLETALRRLSLRRENYILERKFFEDDQERKLRSLAEKGEIHSG---SVTPTDSIMSLGTHSRLSEFTGVSGMSYSSRSY-------------------LPEKLQIVKPLEGSATLHHWQQLAQPNLGGIL 495
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Xenopus
Match: TRAK1 (trafficking protein, kinesin binding 1 [Source:NCBI gene;Acc:100135152]) HSP 1 Score: 178.718 bits (452), Expect = 3.163e-45 Identity = 165/577 (28.60%), Postives = 271/577 (46.97%), Query Frame = 3
Query: 87 EVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKD-----------------TIIAEQSRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPS--GGNYLL-RKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAFRHRQNRCQTIRSLNTNILNSDSQSLHPQNIYKMPDKLQLVKPIEGSQTLRTWQNLATPSITKAL 1754
EVE+ISL+ E LP Y+L+AD GY H D+++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ K+ +S Q +E ++ D L + + A E E S + + S ++ F D + K + + + LR + +L + + KEQQL++DCV++L D+ + ++ +L KKT+D Q EEI+ LL+ +D++ K + + EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K ++ + V P SLA E E + RK+ II EQ R V + S + D+ T S +++E L+ S NY+L RK ++D E++ G+I++ S S ++ ++ L F + RS +P+KLQ+VKP+EGS TL WQ LA P++ L
Sbjct: 19 EVEIISLLEEQLPHYKLRADT---IYGYDHDDWLQTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKALTERNEYLEEQVEHIKEEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESICSTPLKRNES---ASSVQNYFHFDSLQKKLKDLEDENIV-----LRSEACHLKTETITYEEKEQQLVNDCVKELRDANVQIVSISEELAKKTDDAARQQEEITHLLSQIVDIQKKA-KAVIENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNVISRRYHTLGVFP--LDSLAAEIEGSMRKELQMDDSQVRLNVELTLLIIIVEQFRLFIVF-MIVLLFFSLSNGDKNKKPGTPGTPGS---SDLETALRRLSLRRENYILERKFFEDDQERKLRSLAEKGEIHSG---SVTPTDSIMSLGTHSRLSEFTGVSGMSYSSRSY-------------------LPEKLQIVKPLEGSATLHHWQQLAQPNLGGIL 528
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Xenopus
Match: TRAK1 (trafficking protein, kinesin binding 1 [Source:NCBI gene;Acc:100135152]) HSP 1 Score: 160.999 bits (406), Expect = 1.847e-39 Identity = 125/410 (30.49%), Postives = 206/410 (50.24%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFI---NEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D+++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ K+ +S Q +E ++ D L + + A E E S NE S ++ F D + K + + + LR + +L + + KEQQL++DCV++L D+ + ++ +L KKT+D Q EEI+ LL+ +D++ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K ++ + V P SLA E E + RK+ + + + RV E + +N
Sbjct: 99 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLQTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKALTERNEYLEEQVEHIKEEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESICSTPLKRNESA------SSVQNYFHFDSLQKKLKDLEDENIV-----LRSEACHLKTETITYEEKEQQLVNDCVKELRDANVQIVSISEELAKKTDDAARQQEEITHLLSQIVDIQKKAKAYAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNVISRRYHTLGVFP--LDSLAAEIEGSMRKELQMDDGNHHKRVFETVKNVN 465
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Xenopus
Match: TRAK1 (trafficking protein, kinesin binding 1 [Source:NCBI gene;Acc:100135152]) HSP 1 Score: 156.762 bits (395), Expect = 2.693e-38 Identity = 119/387 (30.75%), Postives = 197/387 (50.90%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKD 1241
EVE+ISL+ E LP Y+L+AD GY H D+++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ K+ +S Q +E ++ D L + + A E E S + + S ++ F D + K + + + LR + +L + + KEQQL++DCV++L D+ + ++ +L KKT+D Q EEI+ LL+ +D++ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K ++ + V P SLA E E + RK+
Sbjct: 10 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLQTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKALTERNEYLEEQVEHIKEEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESICSTPLKRNES---ASSVQNYFHFDSLQKKLKDLEDENIV-----LRSEACHLKTETITYEEKEQQLVNDCVKELRDANVQIVSISEELAKKTDDAARQQEEITHLLSQIVDIQKKAKAYAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNVISRRYHTLGVFPL--DSLAAEIEGSMRKE 356
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Xenopus
Match: TRAK1 (trafficking protein, kinesin binding 1 [Source:NCBI gene;Acc:100135152]) HSP 1 Score: 156.762 bits (395), Expect = 2.903e-38 Identity = 119/387 (30.75%), Postives = 197/387 (50.90%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKD 1241
EVE+ISL+ E LP Y+L+AD GY H D+++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ K+ +S Q +E ++ D L + + A E E S + + S ++ F D + K + + + LR + +L + + KEQQL++DCV++L D+ + ++ +L KKT+D Q EEI+ LL+ +D++ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K ++ + V P SLA E E + RK+
Sbjct: 27 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLQTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKALTERNEYLEEQVEHIKEEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESICSTPLKRNES---ASSVQNYFHFDSLQKKLKDLEDENIV-----LRSEACHLKTETITYEEKEQQLVNDCVKELRDANVQIVSISEELAKKTDDAARQQEEITHLLSQIVDIQKKAKAYAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNVISRRYHTLGVFPL--DSLAAEIEGSMRKE 373
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Mouse
Match: Trak1 (trafficking protein, kinesin binding 1 [Source:MGI Symbol;Acc:MGI:1914345]) HSP 1 Score: 161.384 bits (407), Expect = 7.535e-40 Identity = 129/412 (31.31%), Postives = 206/412 (50.00%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K M + + S+ SLA E E T RK+ + E +S I RV E R +N
Sbjct: 38 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKSCAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNK----TMPTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEELESPDITHQKRVFETVRNVN 407
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Mouse
Match: Trak1 (trafficking protein, kinesin binding 1 [Source:MGI Symbol;Acc:MGI:1914345]) HSP 1 Score: 161.384 bits (407), Expect = 9.573e-40 Identity = 129/412 (31.31%), Postives = 206/412 (50.00%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K M + + S+ SLA E E T RK+ + E +S I RV E R +N
Sbjct: 67 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKSCAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNK----TMPTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEELESPDITHQKRVFETVRNVN 436
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Mouse
Match: Trak2 (trafficking protein, kinesin binding 2 [Source:MGI Symbol;Acc:MGI:1918077]) HSP 1 Score: 131.339 bits (329), Expect = 8.549e-31 Identity = 115/411 (27.98%), Postives = 204/411 (49.64%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITE-LTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEM---MKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINS 1304
EVEL++L+ E LP+Y+L+ D Y++ D+ ++ + ++ E L+ ++T Y +L RV +MT+TY D + L+ E+ ++ AA IG LL+RN L ++ +E+QL + D + NQ +E + D L +S A E + S + + FSL++ LD ++ K E + + LR + ++ + + KEQQL++DCV++L ++ + R+T +L+ K+++ L EEIS LL+ +DL++K+ + E + L L+ + Q LT EL +L+DR EC+ +L+E Q++I++L K Q G + G+SLA E E T RK + E+S + + +Q R ++
Sbjct: 39 PEVELVNLLEEQLPQYKLRVDS---LFLYENQDWAQSSHQQQDAPETLSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNEALEEQLGQAFDQV---------------------------NQLQHELSKKDELLRIVSIASEESETDSSCSTPLRFNES---FSLSQGLLQLDMLHEKLRELEEENMA-----LRSKACHIKTETFTYEEKEQQLVNDCVKELRETNAQMSRMTEELSGKSDELLRYQEEISSLLSQIVDLQHKLKEHVIEKEELRLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSKSGPSAHLCFSQSYGVFT-----GESLAAEIEGTMRKKLSLDEESVSKQKAQQKRVFDT 406
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Mouse
Match: Trak2 (trafficking protein, kinesin binding 2 [Source:MGI Symbol;Acc:MGI:1918077]) HSP 1 Score: 130.954 bits (328), Expect = 2.483e-30 Identity = 115/411 (27.98%), Postives = 204/411 (49.64%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITE-LTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEM---MKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINS 1304
EVEL++L+ E LP+Y+L+ D Y++ D+ ++ + ++ E L+ ++T Y +L RV +MT+TY D + L+ E+ ++ AA IG LL+RN L ++ +E+QL + D + NQ +E + D L +S A E + S + + FSL++ LD ++ K E + + LR + ++ + + KEQQL++DCV++L ++ + R+T +L+ K+++ L EEIS LL+ +DL++K+ + E + L L+ + Q LT EL +L+DR EC+ +L+E Q++I++L K Q G + G+SLA E E T RK + E+S + + +Q R ++
Sbjct: 39 PEVELVNLLEEQLPQYKLRVDS---LFLYENQDWAQSSHQQQDAPETLSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNEALEEQLGQAFDQV---------------------------NQLQHELSKKDELLRIVSIASEESETDSSCSTPLRFNES---FSLSQGLLQLDMLHEKLRELEEENMA-----LRSKACHIKTETFTYEEKEQQLVNDCVKELRETNAQMSRMTEELSGKSDELLRYQEEISSLLSQIVDLQHKLKEHVIEKEELRLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSKSGPSAHLCFSQSYGVFT-----GESLAAEIEGTMRKKLSLDEESVSKQKAQQKRVFDT 406
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Mouse
Match: Trak1 (trafficking protein, kinesin binding 1 [Source:MGI Symbol;Acc:MGI:1914345]) HSP 1 Score: 116.701 bits (291), Expect = 4.036e-26 Identity = 102/352 (28.98%), Postives = 169/352 (48.01%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
+LC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K M + + S+ SLA E E T RK+ + E +S I RV E R +N
Sbjct: 85 VLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKSCAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKT----MPTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEELESPDITHQKRVFETVRNVN 397
BLAST of HAP1 N-terminal domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6PD31|TRAK1_MOUSE (Trafficking kinesin-binding protein 1 OS=Mus musculus OX=10090 GN=Trak1 PE=1 SV=1) HSP 1 Score: 161.384 bits (407), Expect = 5.271e-39 Identity = 129/412 (31.31%), Postives = 206/412 (50.00%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K M + + S+ SLA E E T RK+ + E +S I RV E R +N
Sbjct: 38 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKSCAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNK----TMPTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEELESPDITHQKRVFETVRNVN 407
BLAST of HAP1 N-terminal domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UPV9|TRAK1_HUMAN (Trafficking kinesin-binding protein 1 OS=Homo sapiens OX=9606 GN=TRAK1 PE=1 SV=1) HSP 1 Score: 160.614 bits (405), Expect = 9.418e-39 Identity = 129/412 (31.31%), Postives = 206/412 (50.00%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENI-TELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE-QSRAI----RVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D++ I + +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S + + S ++ F LD + K + + + LR + + L + + KEQQL++DCV++L D+ + ++ +L KKT D Q EEI+ LL+ +DL+ K EN+ L+ L + Q LT EL +L D+Y EC+ +L+E Q++++ L K + + S+ SLA E E T RK+ + E +S I RV E R IN
Sbjct: 39 PEVEIISLLEEQLPHYKLRADT---IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES---SSSVQNYFHLDSLQKKLKDLEEENVV-----LRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS--RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNIN 410
BLAST of HAP1 N-terminal domain-containing protein vs. UniProt/SwissProt
Match: sp|O60296|TRAK2_HUMAN (Trafficking kinesin-binding protein 2 OS=Homo sapiens OX=9606 GN=TRAK2 PE=1 SV=2) HSP 1 Score: 129.028 bits (323), Expect = 7.521e-29 Identity = 111/406 (27.34%), Postives = 200/406 (49.26%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITE-LTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTI 1298
EVEL+SL+ E LP+YRLK D Y++ D+ ++ + ++ ++ L+ ++T Y +L RV +MT+TY D + L+ E+ ++ AA IG LL+RN L ++ ++E+QL + D + NQ +E D L +S A E + S + + FSL++ L+ + K E + + LR + ++ + + KEQQL+ DCV++L ++ + R+T +L+ K+++ + EE+S LL+ +DL++K+ + E + L L+ + Q LT EL +L+DR EC+ +L+E Q++I++L + + +S G+SLA E E T RK + E+S + Q + +
Sbjct: 39 PEVELVSLLEEQLPQYRLKVDT---LFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQV---------------------------NQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNES---FSLSQGLLQLEMLQEKLKELEEENMA-----LRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGP--TAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRV 404
BLAST of HAP1 N-terminal domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R2H7|TRAK2_RAT (Trafficking kinesin-binding protein 2 OS=Rattus norvegicus OX=10116 GN=Trak2 PE=1 SV=2) HSP 1 Score: 127.102 bits (318), Expect = 2.318e-28 Identity = 114/411 (27.74%), Postives = 204/411 (49.64%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITE-LTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEM---MKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINS 1304
EVEL++L+ E LP+Y+L+ D Y++ D+ ++ + ++ +E L+ ++T Y +L RV +MT+TY D + L+ E+ ++ AA IG LL+RN L ++ ++E+QL + D + NQ +E + + L +S A E + S + + FSL++ LD ++ K E + + LR + ++ + + KEQ+LI+DCV +L ++ + R+T +L+ K+++ L EEIS LL+ +DL++K+ + E + L L+ + Q LT EL +L+DR EC+ +L+E Q++I++L K Q G + G+SLA E E T RK + E+S + +Q R ++
Sbjct: 39 PEVELVNLLEEQLPQYKLRVDS---LFLYENQDWSQSSHQQQDASETLSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQV---------------------------NQLQHELSKKEELLRIVSIASEESETDSSCSTPLRFNES---FSLSQGLLQLDMMHEKLKELEEENMA-----LRSKACHIKTETFTYEEKEQKLINDCVNELRETNAQMSRMTEELSGKSDELLRYQEEISSLLSQIVDLQHKLKEHVIEKEELRLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRNKAGPSAHLCFSQAYGVFA-----GESLAAEIEGTMRKKLSLDEESVFKQKAQQKRVFDT 406
BLAST of HAP1 N-terminal domain-containing protein vs. UniProt/SwissProt
Match: sp|Q960V3|MILT_DROME (Trafficking kinesin-binding protein milt OS=Drosophila melanogaster OX=7227 GN=milt PE=1 SV=1) HSP 1 Score: 65.0846 bits (157), Expect = 3.288e-9 Identity = 44/151 (29.14%), Postives = 77/151 (50.99%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQ-IQGFRSVSPDIGQSL 1208
L+ + T L D ++ E+QL+ D QL D+ D L+ +L ++ + QHE+I L + E ++H+L +ND +S L + Q L EL + + RY+E + LL+ QDQ++Q K+ + + + G + +G SL
Sbjct: 255 LKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSL 405
BLAST of HAP1 N-terminal domain-containing protein vs. TrEMBL
Match: A0A4S2LM71 (HAP1 N-terminal domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006227 PE=4 SV=1) HSP 1 Score: 224.557 bits (571), Expect = 1.627e-56 Identity = 207/680 (30.44%), Postives = 317/680 (46.62%), Query Frame = 3
Query: 84 AEVELISLVY---ENLPRYRLKADCNIQFSGYQHSDFIRA----------ENIIENITELTNT--------------------------------QIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXX-XXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDI-----------------------------------------------GQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAF-----RHRQNRCQ----------TIRSLNT-------------NILNSDSQSLHPQNIYKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFE 1760
A++ELISL +PRYRL+ D F GY+H DF RA +++ ++ +ELT QI+ TL+YFLLCGLRVS+M TYED A+ L+EE++ ++ AA IG NLL +N +LE+RL+ E +L+AS+DT+SQL+H L +KD LL+ + ++E+ D T + WIS D G N G N S+ VN L K+ +LEEEN LR++ L AD +D E LI DC RQL+ + + L+ +L KK++ +LNQ E++RLLT +DLE+++ +L EN+ L+++L++ Q Q + ELT LRD+YDEC++L NE + ++R L K+ ++ ++ G+ S SP G SLA + T D + R R M+QAR + S + +++ + EPS E + Y+ TGD TS +Q S + S+C ++ RH C+ T+ ++ T ++L+SD ++ Q+ ++P +LQL+KP++GS+ L+ WQ LATPS T ALFE
Sbjct: 84 ADIELISLTGNREARIPRYRLRVDPCTAFLGYKHKDFSRARRATRGSCVSQSVPKSPSELTTVPDTDSIAEDHLDDEASSDCQTSDDETSSLTVEQIEHTLDYFLLCGLRVSQMARTYEDLEAITHLLEEKQNDLELAAKIGKNLLDKNNELERRLSDTERRLAASEDTVSQLQHNLSIKDSLLQIYSRDHVDESGDDGTTSS---------GWISPLNGIDPRSG-----NGAG-----------NLSVSSVNFTQLNRKVRELEEENYILREERNRLTMTADQLDEHETALIRDCARQLVSANMHIRTLSDELAKKSDAFLNQQSEVTRLLTRGLDLESRVKQLAAENEMLVNRLKESQGNQQRVANELTSLRDKYDECLSLYNEARSEVRALRKRSRRAHLRS--GYLS-SPSTMTSYSTPPYLLCMDSNTVSCSTHAQGSDGSSSSLDTTTNGTANDRTGGTSLATDLARTAANDGANSNVDRLFRTMDQARHVREGCDAASRDKSAQPDYAHDDNVSSSGFVSGSEPS-----------ELVARSSGYQ--TGDNQTSTPRNQ-RPLSPLSARSWCGRDSLEEQLKRHSWLGCEPRKGSLPDEPTLSAVGTLYPRNSDENLLAESLLSSDPTVVYGQSYSRLPRRLQLIKPLDGSEVLQHWQRLATPSFTNALFE 721
BLAST of HAP1 N-terminal domain-containing protein vs. TrEMBL
Match: A0A4S2LM42 (HAP1 N-terminal domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006227 PE=4 SV=1) HSP 1 Score: 219.935 bits (559), Expect = 8.997e-56 Identity = 208/680 (30.59%), Postives = 314/680 (46.18%), Query Frame = 3
Query: 84 AEVELISLVY---ENLPRYRLKADCNIQFSGYQHSDFIRA----------ENIIENITELTNT--------------------------------QIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXX-XXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDI-----------------------------------------------GQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAF-----RHRQNRCQ----------TIRSLNT--------NILNSDSQSLHPQNIY-----KMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFE 1760
A++ELISL +PRYRL+ D F GY+H DF RA +++ ++ +ELT QI+ TL+YFLLCGLRVS+M TYED A+ L+EE++ ++ AA IG NLL +N +LE+RL+ E +L+AS+DT+SQL+H L +KD LL+ + ++E+ D T + WIS D G N G N S+ VN L K+ +LEEEN LR++ L AD +D E LI DC RQL+ + + L+ +L KK++ +LNQ E++RLLT +DLE+++ +L EN+ L+++L++ Q Q + ELT LRD+YDEC++L NE + ++R L K+ ++ ++ G+ S SP G SLA + T D + R R M+QAR + S + +++ + EPS E + Y+ TGD TS +Q S + S+C ++ RH C+ T+ ++ T N+L S P +Y ++P +LQL+KP++GS+ L+ WQ LATPS T ALFE
Sbjct: 84 ADIELISLTGNREARIPRYRLRVDPCTAFLGYKHKDFSRARRATRGSCVSQSVPKSPSELTTVPDTDSIAEDHLDDEASSDCQTSDDETSSLTVEQIEHTLDYFLLCGLRVSQMARTYEDLEAITHLLEEKQNDLELAAKIGKNLLDKNNELERRLSDTERRLAASEDTVSQLQHNLSIKDSLLQIYSRDHVDESGDDGTTSS---------GWISPLNGIDPRSG-----NGAG-----------NLSVSSVNFTQLNRKVRELEEENYILREERNRLTMTADQLDEHETALIRDCARQLVSANMHIRTLSDELAKKSDAFLNQQSEVTRLLTRGLDLESRVKQLAAENEMLVNRLKESQGNQQRVANELTSLRDKYDECLSLYNEARSEVRALRKRSRRAHLR--SGYLS-SPSTMTSYSTPPYLLCMDSNTVSCSTHAQGSDGSSSSLDTTTNGTANDRTGGTSLATDLARTAANDGANSNVDRLFRTMDQARHVREGCDAASRDKSAQPDYAHDDNVSSSGFVSGSEPS-----------ELVARSSGYQ--TGDNQTSTPRNQ-RPLSPLSARSWCGRDSLEEQLKRHSWLGCEPRKGSLPDEPTLSAVGTLYPRNSDENLLAESLLSSDPTVVYGQSYSRLPRRLQLIKPLDGSEVLQHWQRLATPSFTNALFE 721
BLAST of HAP1 N-terminal domain-containing protein vs. TrEMBL
Match: A0A4S2LM50 (HAP1 N-terminal domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006227 PE=4 SV=1) HSP 1 Score: 219.55 bits (558), Expect = 1.268e-55 Identity = 208/680 (30.59%), Postives = 314/680 (46.18%), Query Frame = 3
Query: 84 AEVELISLVY---ENLPRYRLKADCNIQFSGYQHSDFIRA----------ENIIENITELTNT--------------------------------QIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXX-XXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDI-----------------------------------------------GQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAF-----RHRQNRCQ----------TIRSLNT--------NILNSDSQSLHPQNIY-----KMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFE 1760
A++ELISL +PRYRL+ D F GY+H DF RA +++ ++ +ELT QI+ TL+YFLLCGLRVS+M TYED A+ L+EE++ ++ AA IG NLL +N +LE+RL+ E +L+AS+DT+SQL+H L +KD LL+ + ++E+ D T + WIS D G N G N S+ VN L K+ +LEEEN LR++ L AD +D E LI DC RQL+ + + L+ +L KK++ +LNQ E++RLLT +DLE+++ +L EN+ L+++L++ Q Q + ELT LRD+YDEC++L NE + ++R L K+ ++ ++ G+ S SP G SLA + T D + R R M+QAR + S + +++ + EPS + R S + TGD TS +Q S + S+C ++ RH C+ T+ ++ T N+L S P +Y ++P +LQL+KP++GS+ L+ WQ LATPS T ALFE
Sbjct: 84 ADIELISLTGNREARIPRYRLRVDPCTAFLGYKHKDFSRARRATRGSCVSQSVPKSPSELTTVPDTDSIAEDHLDDEASSDCQTSDDETSSLTVEQIEHTLDYFLLCGLRVSQMARTYEDLEAITHLLEEKQNDLELAAKIGKNLLDKNNELERRLSDTERRLAASEDTVSQLQHNLSIKDSLLQIYSRDHVDESGDDGTTSS---------GWISPLNGIDPRSG-----NGAG-----------NLSVSSVNFTQLNRKVRELEEENYILREERNRLTMTADQLDEHETALIRDCARQLVSANMHIRTLSDELAKKSDAFLNQQSEVTRLLTRGLDLESRVKQLAAENEMLVNRLKESQGNQQRVANELTSLRDKYDECLSLYNEARSEVRALRKRSRRAHLR--SGYLS-SPSTMTSYSTPPYLLCMDSNTVSCSTHAQGSDGSSSSLDTTTNGTANDRTGGTSLATDLARTAANDGANSNVDRLFRTMDQARHVREGCDAASRDKSAQPDYAHDDNVSSSGFVSGSEPS--ELVARSSGYQ-----------TGDNQTSTPRNQ-RPLSPLSARSWCGRDSLEEQLKRHSWLGCEPRKGSLPDEPTLSAVGTLYPRNSDENLLAESLLSSDPTVVYGQSYSRLPRRLQLIKPLDGSEVLQHWQRLATPSFTNALFE 721
BLAST of HAP1 N-terminal domain-containing protein vs. TrEMBL
Match: A0A4S2LUA5 (HAP1 N-terminal domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006227 PE=4 SV=1) HSP 1 Score: 220.705 bits (561), Expect = 2.377e-55 Identity = 210/690 (30.43%), Postives = 317/690 (45.94%), Query Frame = 3
Query: 84 AEVELISLVY---ENLPRYRLKADCNIQFSGYQHSDFIRA----------ENIIENITELTNT--------------------------------QIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXX-XHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDI-----------------------------------------------GQSLAMEFEDTCRKDTIIAEQSRAIRVMEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAF-----RHRQNRCQ----------TIRSLNT--------NILNSDSQSLHPQNIY-----KMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRG 1790
A++ELISL +PRYRL+ D F GY+H DF RA +++ ++ +ELT QI+ TL+YFLLCGLRVS+M TYED A+ L+EE++ ++ AA IG NLL +N +LE+RL+ E +L+AS+DT+SQL+H L +KD LL++ + ++E+ D T + WIS D G N G N S+ VN L K+ +LEEEN LR++ L AD +D E LI DC RQL+ + + L+ +L KK++ +LNQ E++RLLT +DLE+++ +L EN+ L+++L++ Q Q + ELT LRD+YDEC++L NE + ++R L K+ ++ ++ G+ S SP G SLA + T D + R R M+QAR + S + +++ + EPS E + Y+ TGD TS +Q S + S+C ++ RH C+ T+ ++ T N+L S P +Y ++P +LQL+KP++GS+ L+ WQ LATPS T ALFE V R
Sbjct: 84 ADIELISLTGNREARIPRYRLRVDPCTAFLGYKHKDFSRARRATRGSCVSQSVPKSPSELTTVPDTDSIAEDHLDDEASSDCQTSDDETSSLTVEQIEHTLDYFLLCGLRVSQMARTYEDLEAITHLLEEKQNDLELAAKIGKNLLDKNNELERRLSDTERRLAASEDTVSQLQHNLSIKDSLLQIYSRDHVDESGDDGTTSS---------GWISPLNGIDPRSG-----NGAG-----------NLSVSSVNFTQLNRKVRELEEENYILREERNRLTMTADQLDEHETALIRDCARQLVSANMHIRTLSDELAKKSDAFLNQQSEVTRLLTRGLDLESRVKQLAAENEMLVNRLKESQGNQQRVANELTSLRDKYDECLSLYNEARSEVRALRKRSRRAHLR--SGYLS-SPSTMTSYSTPPYLLCMDSNTVSCSTHAQGSDGSSSSLDTTTNGTANDRTGGTSLATDLARTAANDGANSNVDRLFRTMDQARHVREGCDAASRDKSAQPDYAHDDNVSSSGFVSGSEPS-----------ELVARSSGYQ--TGDNQTSTPRNQ-RPLSPLSARSWCGRDSLEEQLKRHSWLGCEPRKGSLPDEPTLSAVGTLYPRNSDENLLAESLLSSDPTVVYGQSYSRLPRRLQLIKPLDGSEVLQHWQRLATPSFTNALFEAPLPGVQSRA 731
BLAST of HAP1 N-terminal domain-containing protein vs. TrEMBL
Match: A0A4S2LM31 (HAP1 N-terminal domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006227 PE=4 SV=1) HSP 1 Score: 189.889 bits (481), Expect = 3.878e-47 Identity = 146/405 (36.05%), Postives = 221/405 (54.57%), Query Frame = 3
Query: 84 AEVELISLVY---ENLPRYRLKADCNIQFSGYQHSDFIRA----------ENIIENITELTNT--------------------------------QIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXX-XXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMK 1160
A++ELISL +PRYRL+ D F GY+H DF RA +++ ++ +ELT QI+ TL+YFLLCGLRVS+M TYED A+ L+EE++ ++ AA IG NLL +N +LE+RL+ E +L+AS+DT+SQL+H L +KD LL+ + ++E+ D T + WIS D G N G N S+ VN L K+ +LEEEN LR++ L AD +D E LI DC RQL+ + + L+ +L KK++ +LNQ E++RLLT +DLE+++ +L EN+ L+++L++ Q Q + ELT LRD+YDEC++L NE + ++R L K+ ++ ++
Sbjct: 84 ADIELISLTGNREARIPRYRLRVDPCTAFLGYKHKDFSRARRATRGSCVSQSVPKSPSELTTVPDTDSIAEDHLDDEASSDCQTSDDETSSLTVEQIEHTLDYFLLCGLRVSQMARTYEDLEAITHLLEEKQNDLELAAKIGKNLLDKNNELERRLSDTERRLAASEDTVSQLQHNLSIKDSLLQIYSRDHVDESGDDGTTSS---------GWISPLNGIDPRSG-----NGAG-----------NLSVSSVNFTQLNRKVRELEEENYILREERNRLTMTADQLDEHETALIRDCARQLVSANMHIRTLSDELAKKSDAFLNQQSEVTRLLTRGLDLESRVKQLAAENEMLVNRLKESQGNQQRVANELTSLRDKYDECLSLYNEARSEVRALRKRSRRAHLR 463
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Cavefish
Match: trak1a (trafficking kinesin protein 1 [Source:NCBI gene;Acc:103035336]) HSP 1 Score: 160.614 bits (405), Expect = 1.212e-39 Identity = 133/414 (32.13%), Postives = 205/414 (49.52%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENIT-ELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESN-FSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK-----DTIIAEQS-RAIRVMEQARTIN 1301
EVE+ISL+ E LP Y+L+AD GY H D++ I + T +LT QI++TL+YFLLC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S D SL+ N F LD + K + + + LR + +L + + KEQQL++DCV++L D+ + L +L KKT D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L D+Y EC+ +L+E Q++++ N + K + + F S+ SLA E E T RK D + EQ RV + + IN
Sbjct: 10 PEVEIISLLEEQLPHYQLRADT---IYGYDHDDWLHTPLISPDTTIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLSERNEFLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEGESATSTPVHRNDS----SLSVPNYFPLDSLQKKLKDLEEENIV-----LRSEACHLETETISYEEKEQQLVNDCVKELRDANLQLSSLAEELAKKTEDASRQQEEITHLLSQIVDLQKKAKSYAVENEELTQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELK--NFRNKTMPLSTPRRFHSLGLFPLDSLAAEIEGTMRKEIQMSDPEVEEQRLHPKRVFQTVKNIN 382
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Cavefish
Match: trak1a (trafficking kinesin protein 1 [Source:NCBI gene;Acc:103035336]) HSP 1 Score: 114.775 bits (286), Expect = 8.107e-26 Identity = 103/352 (29.26%), Postives = 168/352 (47.73%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESN-FSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIA----EQSRAIRVMEQARTIN 1301
+LC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S D SL+ N F LD + K + + + LR + +L + + KEQQL++DCV++L D+ + L +L KKT D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L D+Y EC+ +L+E Q++++ N + K + + F S+ SLA E E T RK+ ++ E+ RV + + IN
Sbjct: 22 VLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLSERNEFLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEGESATSTPVHRNDS----SLSVPNYFPLDSLQKKLKDLEEENIV-----LRSEACHLETETISYEEKEQQLVNDCVKELRDANLQLSSLAEELAKKTEDASRQQEEITHLLSQIVDLQKKAKSYAVENEELTQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELK--NFRNKTMPLSTPRRFHSLGLFPLDSLAAEIEGTMRKEIQMSDPEVEELHPKRVFQTVKNIN 335
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Cavefish
Match: trak1a (trafficking kinesin protein 1 [Source:NCBI gene;Acc:103035336]) HSP 1 Score: 114.775 bits (286), Expect = 2.230e-25 Identity = 105/354 (29.66%), Postives = 167/354 (47.18%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESN-FSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK-----DTIIAEQS-RAIRVMEQARTIN 1301
+LC RV +MT+TY D A+ L+EE++ ++ AA IG +LL++N L +R +E+Q+ ++ +S Q +E ++ D L + + A E E S D SL+ N F LD + K + + + LR + +L + + KEQQL++DCV++L D+ + L +L KKT D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L D+Y EC+ +L+E Q++++ N + K + + F S+ SLA E E T RK D + EQ RV + + IN
Sbjct: 51 VLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLSERNEFLEEQVEHIREEVS---------------------------QLRHELSMKDELLQFYTSAAEESEGESATSTPVHRNDS----SLSVPNYFPLDSLQKKLKDLEEENIV-----LRSEACHLETETISYEEKEQQLVNDCVKELRDANLQLSSLAEELAKKTEDASRQQEEITHLLSQIVDLQKKAKSYAVENEELTQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELK--NFRNKTMPLSTPRRFHSLGLFPLDSLAAEIEGTMRKEIQMSDPEVEEQRLHPKRVFQTVKNIN 366
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Cavefish
Match: trak2 (trafficking protein, kinesin binding 2 [Source:ZFIN;Acc:ZDB-GENE-030131-7496]) HSP 1 Score: 109.768 bits (273), Expect = 7.527e-24 Identity = 105/384 (27.34%), Postives = 182/384 (47.40%), Query Frame = 3
Query: 168 YQHSDFIRAENIIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKDTIIAE------QSRAIRVMEQARTIN 1301
Y+ D++ + +I+ L ++T Y +L RV +MT+TY D + L+ E+ ++ AA IG +LLQRN L++R +E+QL+ + D Q HQL + L + A + ++T + C+ A+ +E S + + L E N SL R + ++L + KEQQL+ DCV++L +++ + LT +L++K D L EEI++LL+ ++L++++ L E + L L+ + Q LT EL D+ DR EC+ +L+E Q++I++L + K ++ S P SLA E E + R++ + E QS RV R++N
Sbjct: 37 YEGQDWVISPEDTSSISPLL---AEETFRY-MLSADRVEQMTKTYNDIEVVTHLLAERDRDLELAARIGQSLLQRNHVLQERTENLEEQLTQALD---QQVHQLQHEVCKKDELLRMVASASEESETDSSCSTPLRPPPPAVGAFTLSQLEALQSKLQD---------LEEENLSL----------------------RSEASHLKKETITYEEKEQQLVSDCVKELESNSQMIT-LTEELSQKNEDLLRHQEEIAQLLSQIVELQHRVKELALEKEELRIHLQASKDAQRQLTAELKDMSDRNVECVGMLHESQEEIKEL--RSKNTPAAGLRRHLSYGPYPMDSLAAEIEGSMRREMSVEEEMAFEDQSAHKRVFRTVRSVN 379
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Cavefish
Match: trak2 (trafficking protein, kinesin binding 2 [Source:ZFIN;Acc:ZDB-GENE-030131-7496]) HSP 1 Score: 103.605 bits (257), Expect = 5.235e-22 Identity = 90/294 (30.61%), Postives = 152/294 (51.70%), Query Frame = 3
Query: 258 FLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKK 1139
+L RV +MT+TY D + L+ E+ ++ AA IG +LLQRN L++R +E+QL+ + D + QL+H++ KD+LLR++ + EE+E T + C+ A+ +E S + + L E N SL R + ++L + KEQQL+ DCV++L +S + LT +L++K D L EEI++LL+ ++L++++ L E + L L+ + Q LT EL D+ DR EC+ +L+E Q++I++L K
Sbjct: 1 VVLSADRVEQMTKTYNDIEVVTHLLAERDRDLELAARIGQSLLQRNHVLQERTENLEEQLTQALDQVHQLQHEVCKKDELLRMVASASEESE----TDSSCSTPLRPPPPAVGAFTLSQLEALQSKLQD---------LEEENLSL----------------------RSEASHLKKETITYEEKEQQLVSDCVKELRESNSQMITLTEELSQKNEDLLRHQEEIAQLLSQIVELQHRVKELALEKEELRIHLQASKDAQRQLTAELKDMSDRNVECVGMLHESQEEIKELRSK 259
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005027.1 (pep scaffold:Pmarinus_7.0:GL476744:166982:220099:-1 gene:ENSPMAG00000004500.1 transcript:ENSPMAT00000005027.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 134.035 bits (336), Expect = 4.310e-32 Identity = 110/396 (27.78%), Postives = 186/396 (46.97%), Query Frame = 3
Query: 84 AEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIEN---------ITELTNTQIQKTLEYF-LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKD 1241
EVE+ISL+ E LP Y L+A+ GY+H D++ + + + +L+ Q ++TL Y LLC RV +MT TY D A+ L+EE++ ++ AA IG LL++N L +R+ +ED+L + T+ Q+ H LLH ED + T ++ + + ++ H + E L + N +LR + ++ + + KEQQL++DCV+ L D+ + LT +L ++ D Q EEI+ LL+ +DL+ + EN+ L+ L + Q LT EL +L +RY EC+++L+E Q++ + L + ++ G D SLA E E + R++
Sbjct: 13 PEVEIISLLEERLPHYTLRANA---VYGYEHRDWLHSPVLSPDDGDGDGAYASPDLSPEQAEETLRYMSLLCSERVGQMTRTYSDIDAVTHLLEEKERDLELAARIGQTLLEKNKSLSERVEHLEDEL---EHTLEQVNQLRHDLSMKDELLHIYTHTVEDCESDSSGSTPLERSGGSLVGGHIPAQLDAVHKRLKE---------LEDENL----------------------RLRSKACHIKTETISYEEKEQQLVNDCVKGLRDAHLQIGHLTDELGRRNEDSARQQEEITHLLSQIVDLQRRAKAYQLENEELVQHLSAAKEAQHELTAELRELEERYAECVDMLHEAQEESKGLRSQTVMSTPRRYNGSLLYPMD---SLAAEIEGSMRRE 368
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008475.1 (pep scaffold:Pmarinus_7.0:GL476349:241765:267965:-1 gene:ENSPMAG00000007644.1 transcript:ENSPMAT00000008475.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 122.479 bits (306), Expect = 1.219e-28 Identity = 121/425 (28.47%), Postives = 196/425 (46.12%), Query Frame = 3
Query: 87 EVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITELTNTQIQKTL-EYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNE-DNVEGFHSFINEYGDHPYFFS--LTESNFSLDKVXXXXXXXXXXXXXXXXTKLRD---QHTNLHSHADFMDN-------KEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQL-NKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK-----DTIIAEQSRAIRVMEQARTIN 1301
EVE++SL+ E LP +RL+AD + GY D+IR + + ++ + +Y LLC RV +MT+TY D A+ L+EE++ ++ AA IG +LLQ+ L R T+E+Q+ + E++ Q ++ + + L + + +E DN S + P FS + S +D ++ KLRD ++ +L S A + N KE QL++DCVR+L S V LT +L +++ D Q EEI+ LL+ +DL+ K+ +N+ L L + Q LT EL +L+++ EC +L+E Q+ ++ L N+ ++ + + P SLA E E T RK D + R RV E RT N
Sbjct: 1 EVEVVSLMEERLPLFRLRADSVL---GYDRDDWIRTPVLPPDAELELGLELVEETLKYMLLCADRVGQMTKTYSDIDAVTRLLEEKERDVELAARIGQSLLQKIKVLTDRNETLEEQIGHA---------------------------TEEAAQLRHDLAMKEELLQIYTGSSDENDNAPKSSSPL------PKHFSTQIRSSGLHMDTIHR---------------KLRDLEEENISLRSEASQLQNETIDYEEKEDQLVNDCVRELRTSNSQVLTLTEELARRSEDASRQQEEITHLLSQIVDLQKKVKTYTADNEELTQHLSAAKDAQRQLTAELAELQNKLVECTEMLHEAQEDVKNLRNQTAPSTNAERWRHSHTHFPM--DSLAAEIEGTMRKTLKLEDGVPKAYQR--RVFETVRTAN 370
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003063.1 (pep scaffold:Pmarinus_7.0:GL481277:1:21863:1 gene:ENSPMAG00000002783.1 transcript:ENSPMAT00000003063.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 85.1149 bits (209), Expect = 4.663e-17 Identity = 60/196 (30.61%), Postives = 104/196 (53.06%), Query Frame = 3
Query: 756 KLRDQHTNLHSHADFMDN-------KEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQ----SLAMEFEDTCRKDTI---IAEQSRAIRVMEQARTIN 1301
+L D++ +L S A + N KEQQL+ DCVR+L S+ + +LT +L++++ D + Q EEI++LL+ +DL+ K+ EN+ L L + Q LT E+ +L+++ EC ++L+E Q+ + L + ++ +R P + Q SLA E E T RK+ + + RV + R +N
Sbjct: 88 ELEDENFSLLSEASHLKNETLDYEEKEQQLVTDCVRELRASSAHIAQLTEELSRRSEDAVRQQEEITQLLSQIVDLQKKVKTYSAENEELSQHLGAAKDAQRQLTAEVRELQEKLAECTDMLHEAQEDAKNL----RNQIAPSTTPYRWFHP-LAQFPRDSLAAEIEGTMRKELRWDELGHKGHQKRVFDTVRIVN 278
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Nematostella
Match: EDO43834 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXF1]) HSP 1 Score: 93.5893 bits (231), Expect = 2.949e-19 Identity = 55/170 (32.35%), Postives = 99/170 (58.24%), Query Frame = 3
Query: 804 DNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQI-QGFRSVSPDIGQSLAMEFEDTCRKDTIIAEQSRA--IRVMEQARTINS 1304
+ KE+QL+ DCVRQ++++ + LT +++KK D + Q EEIS+L+ T +DL+N+ +L +N+ L + L Q Q L ++ DL+ +Y+EC +L E Q +++ +NKK + + +G D S+A+E E++ ++D + R RV++ R IN+
Sbjct: 281 EQKERQLVADCVRQMMEAKDHITSLTDEISKKAEDNVRQQEEISQLINTVVDLQNRHKQLHLDNEELQALLNLSQASQDDLQAKVADLQQKYEECFEILMENQQEMKTINKKIETQPPTPAEEGAMGGHHDSKGSIALEIEESVKRDLAHIHEKRMNLARVLQTVRNINT 450 HSP 2 Score: 54.6842 bits (130), Expect = 2.051e-7 Identity = 33/79 (41.77%), Postives = 52/79 (65.82%), Query Frame = 3
Query: 219 ELTNTQIQKTLEYFLLCGLRVSKMTETYEDC-AALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKD 452
+LT Q+Q+TL+YF L R ++MT+T+ D A L+LL E+++ ++ AA+IG +LL+RN L Q+ +E L S D
Sbjct: 122 DLTTEQVQETLKYFTLTSNRTNQMTKTHNDLDAILQLLQEQKEKDLELAASIGQSLLERNKNLMQKTEAMEQYLEKSFD 200
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Medaka
Match: si:dkey-28e7.3 (trafficking kinesin-binding protein 1 [Source:NCBI gene;Acc:101173611]) HSP 1 Score: 114.39 bits (285), Expect = 1.960e-25 Identity = 107/377 (28.38%), Postives = 175/377 (46.42%), Query Frame = 3
Query: 225 TNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQL-NKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK--DTIIAEQSR--AIRVMEQARTINSSWQDTDETSSGF 1340
T +++T F+LC RV ++T+TY D A+ L+EE++ ++ AA IG +LL++N +L R +++QL +K+ I+ Q +E ++ D+L + + ++ + HS I S +F K+ E+ KLR++ L + + +EQ+L+ CV +L + K V L+ +L +K D L Q EEIS LL +DL+ + L EN+ L QL + Q L EL DL+D+Y EC ++L+E ++ I+ L NK +++ SV P SLA E E T RK DT + + R RV E + N + + S F
Sbjct: 36 TKLWLRRTRRRFVLCSDRVGQVTKTYHDIKAVTHLLEEKERDLELAARIGQSLLKQNQELTARNEMLDEQLEVAKEEIA---------------------------QLRHELSMRDDLLQFYASTEELESAQA-HSPIKRNESSGSLSSFIHYDFLQKKLKTLEEENH---------KLREEANELCTETTSYEEQEQELMMVCVEELSSANKQVVDLSEELARKVEDSLRQQEEISSLLAQMVDLQARCKGLSHENEDLSQQLSICREGQAKLRSELKDLQDKYSECEDMLHEAREDIKNLRNKSLPNSTVQRYTALASVLP--MDSLAAEIEGTFRKGLDTPVPSEYRNHPWRVFETVKMANKAGRPRSRCHSPF 373
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Medaka
Match: si:dkey-28e7.3 (trafficking kinesin-binding protein 1 [Source:NCBI gene;Acc:101173611]) HSP 1 Score: 108.612 bits (270), Expect = 1.081e-23 Identity = 104/365 (28.49%), Postives = 169/365 (46.30%), Query Frame = 3
Query: 261 LLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQL-NKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK--DTIIAEQSR--AIRVMEQARTINSSWQDTDETSSGF 1340
+LC RV ++T+TY D A+ L+EE++ ++ AA IG +LL++N +L R +++QL +K+ I+ Q +E ++ D+L + + ++ + HS I S +F K+ E+ KLR++ L + + +EQ+L+ CV +L + K V L+ +L +K D L Q EEIS LL +DL+ + L EN+ L QL + Q L EL DL+D+Y EC ++L+E ++ I+ L NK +++ SV P SLA E E T RK DT + + R RV E + N + + S F
Sbjct: 54 VLCSDRVGQVTKTYHDIKAVTHLLEEKERDLELAARIGQSLLKQNQELTARNEMLDEQLEVAKEEIA---------------------------QLRHELSMRDDLLQFYASTEELESAQA-HSPIKRNESSGSLSSFIHYDFLQKKLKTLEEENH---------KLREEANELCTETTSYEEQEQELMMVCVEELSSANKQVVDLSEELARKVEDSLRQQEEISSLLAQMVDLQARCKGLSHENEDLSQQLSICREGQAKLRSELKDLQDKYSECEDMLHEAREDIKNLRNKSLPNSTVQRYTALASVLP--MDSLAAEIEGTFRKGLDTPVPSEYRNHPWRVFETVKMANKAGRPRSRCHSPF 379
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Medaka
Match: trak1a (trafficking kinesin protein 1 [Source:NCBI gene;Acc:101170301]) HSP 1 Score: 89.7373 bits (221), Expect = 9.110e-18 Identity = 60/185 (32.43%), Postives = 96/185 (51.89%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRK----DTIIAEQSRAIRVMEQARTIN 1301
LR T+L + + KEQQL++DCV++L + + L +L +K++D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L+D+Y EC+ +L+E Q++++ L K + + F S+ SLA E E T RK D E+ RV + + +N
Sbjct: 170 LRSVATHLETETISYEEKEQQLVNDCVKELRGANLQISSLAEELARKSDDASRQQEEITHLLSQIVDLQKKAKLYAVENEELTQHLGAAKDAQRQLTAELRELQDKYAECMEMLHEAQEELKNLRNKSLP--LSNPRRFHSLGLFPMDSLAAEIEGTMRKELQMDDPDVEELHPKRVFQTVKNLN 352
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Medaka
Match: trak1a (trafficking kinesin protein 1 [Source:NCBI gene;Acc:101170301]) HSP 1 Score: 88.9669 bits (219), Expect = 2.135e-17 Identity = 55/161 (34.16%), Postives = 88/161 (54.66%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKD 1241
LR T+L + + KEQQL++DCV++L + + L +L +K++D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L+D+Y EC+ +L+E Q++++ L K + + F S+ SLA E E T RK+
Sbjct: 161 LRSVATHLETETISYEEKEQQLVNDCVKELRGANLQISSLAEELARKSDDASRQQEEITHLLSQIVDLQKKAKLYAVENEELTQHLGAAKDAQRQLTAELRELQDKYAECMEMLHEAQEELKNLRNKSLP--LSNPRRFHSLGLFPMDSLAAEIEGTMRKE 319
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Medaka
Match: trak1a (trafficking kinesin protein 1 [Source:NCBI gene;Acc:101170301]) HSP 1 Score: 88.1965 bits (217), Expect = 2.304e-17 Identity = 55/161 (34.16%), Postives = 88/161 (54.66%), Query Frame = 3
Query: 759 LRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLLTTNIDLENKIHRLLTENDHLISQLRDHQTKQFTLTKELTDLRDRYDECINLLNEKQDQIRQLNKKCKKEMMKQIQGFRSVSPDIGQSLAMEFEDTCRKD 1241
LR T+L + + KEQQL++DCV++L + + L +L +K++D Q EEI+ LL+ +DL+ K EN+ L L + Q LT EL +L+D+Y EC+ +L+E Q++++ L K + + F S+ SLA E E T RK+
Sbjct: 196 LRSVATHLETETISYEEKEQQLVNDCVKELRGANLQISSLAEELARKSDDASRQQEEITHLLSQIVDLQKKAKLYAVENEELTQHLGAAKDAQRQLTAELRELQDKYAECMEMLHEAQEELKNLRNKSLP--LSNPRRFHSLGLFPMDSLAAEIEGTMRKE 354
BLAST of HAP1 N-terminal domain-containing protein vs. Planmine SMEST
Match: SMESG000065238.1 (SMESG000065238.1) HSP 1 Score: 805.053 bits (2078), Expect = 0.000e+0 Identity = 433/434 (99.77%), Postives = 433/434 (99.77%), Query Frame = 3
Query: 1278 MEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAFRHRQNRCQTIRSLNTNILNSDSQSLHPQNIYKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPLILXXXXXXXXXXXXXQIHQSLHSSLVSSXXXXXXXXXPIQSIKSASFASSTTCTYSTVGINQIDTNAKYSSNASSVIITHRKDNTSAFNLNLQLKEEGPKKTIYHDDTPVNEISSCEIDNERNYGPSRSNDIRITGVENNAIESQHALPSWLDRLTVKSLMNSILGYPLPHLHKAIANSPYVTTTINQKPITXXXXXXXXXXXXXXXXRLTNLPPLAQCRFPQSGLNLLATVSDSQSSQNSVLHRISNFCASTELDVVT 2579
MEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAFRHRQNRCQTIRSLNTNILNSDSQSLHPQNIYKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPLILSPSPSSPNSDHS QIHQSLHSSLVSSDCDDADYDDPIQSIKSASFASSTTCTYSTVGINQIDTNAKYSSNASSVIITHRKDNTSAFNLNLQLKEEGPKKTIYHDDTPVNEISSCEIDNERNYGPSRSNDIRITGVENNAIESQHALPSWLDRLTVKSLMNSILGYPLPHLHKAIANSPYVTTTINQKPITSSSVSSGNCGSSSIISRLTNLPPLAQCRFPQSGLNLLATVSDSQSSQNSVLHRISNFCASTELDVVT
Sbjct: 1 MEQARTINSSWQDTDETSSGFTEDLTSSFINTEVEIPLQEPSGGNYLLRKSIQEDCEKRRMYRNNTGDINTSFLDSQIEEASANTVASYCALEAFRHRQNRCQTIRSLNTNILNSDSQSLHPQNIYKMPDKLQLVKPIEGSQTLRTWQNLATPSITKALFEEQSQSVCFRGQQPLILSPSPSSPNSDHSLQIHQSLHSSLVSSDCDDADYDDPIQSIKSASFASSTTCTYSTVGINQIDTNAKYSSNASSVIITHRKDNTSAFNLNLQLKEEGPKKTIYHDDTPVNEISSCEIDNERNYGPSRSNDIRITGVENNAIESQHALPSWLDRLTVKSLMNSILGYPLPHLHKAIANSPYVTTTINQKPITSSSVSSGNCGSSSIISRLTNLPPLAQCRFPQSGLNLLATVSDSQSSQNSVLHRISNFCASTELDVVT 434
BLAST of HAP1 N-terminal domain-containing protein vs. Planmine SMEST
Match: SMESG000065237.1 (SMESG000065237.1) HSP 1 Score: 530.406 bits (1365), Expect = 3.445e-180 Identity = 295/302 (97.68%), Postives = 300/302 (99.34%), Query Frame = 3
Query: 39 MSKEADNQCLYKDTDAEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLL 944
MSKEADNQCLYKDTDAEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISQLRHQLHLKDDLLRLLHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINE+GDHPYFFSLTESNFSLDKVNLKNLESKLSKLEEENTKLR+QHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHE+++ L
Sbjct: 1 MSKEADNQCLYKDTDAEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISQLRHQLHLKDDLLRLLHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEHGDHPYFFSLTESNFSLDKVNLKNLESKLSKLEEENTKLRNQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEKLAGCL 302 HSP 2 Score: 80.4925 bits (197), Expect = 7.642e-16 Identity = 38/40 (95.00%), Postives = 38/40 (95.00%), Query Frame = 1
Query: 925 RKLAGCLLPISTLRIKSTGFSQRMII*FHNYETIKRNSSL 1044
KLAGCLLPISTLRIKSTGFSQRMII FHNYETIKRNSSL
Sbjct: 296 EKLAGCLLPISTLRIKSTGFSQRMIISFHNYETIKRNSSL 335
BLAST of HAP1 N-terminal domain-containing protein vs. Planmine SMEST
Match: SMESG000065237.1 (SMESG000065237.1) HSP 1 Score: 429.098 bits (1102), Expect = 1.031e-141 Identity = 259/302 (85.76%), Postives = 264/302 (87.42%), Query Frame = 3
Query: 39 MSKEADNQCLYKDTDAEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISXXXXXXXXXXXXXXXXHNEIEEAEDSNQTLNECTVIDNLNNWISRAYNEDNVEGFHSFINEYGDHPYFFSLTESNFSLDKVXXXXXXXXXXXXXXXXTKLRDQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEEISRLL 944
MSKEADNQCLYKDTDAEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISQLRHQLHLKDDLLRLLHNEIEEAEDSNQTLN+ FSLTESNFSLDKVNLKNLESKLSKLEEENTKLR+QHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHE+++ L
Sbjct: 1 MSKEADNQCLYKDTDAEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIRAENIIENITELTNTQIQKTLEYFLLCGLRVSKMTETYEDCAALRLLVEEQKAHMDEAANIGLNLLQRNIQLEQRLTTVEDQLSASKDTISQLRHQLHLKDDLLRLLHNEIEEAEDSNQTLND------------------------------------FSLTESNFSLDKVNLKNLESKLSKLEEENTKLRNQHTNLHSHADFMDNKEQQLIDDCVRQLLDSTKTVDRLTTDLNKKTNDYLNQHEKLAGCL 266 HSP 2 Score: 81.2629 bits (199), Expect = 3.197e-16 Identity = 38/40 (95.00%), Postives = 38/40 (95.00%), Query Frame = 1
Query: 925 RKLAGCLLPISTLRIKSTGFSQRMII*FHNYETIKRNSSL 1044
KLAGCLLPISTLRIKSTGFSQRMII FHNYETIKRNSSL
Sbjct: 260 EKLAGCLLPISTLRIKSTGFSQRMIISFHNYETIKRNSSL 299 The following BLAST results are available for this feature:
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of HAP1 N-terminal domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of HAP1 N-terminal domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30016387 ID=SMED30016387|Name=HAP1 N-terminal domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3370bpback to top protein sequence of SMED30016387-orf-1 >SMED30016387-orf-1 ID=SMED30016387-orf-1|Name=SMED30016387-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=863bp MSKEADNQCLYKDTDAEVELISLVYENLPRYRLKADCNIQFSGYQHSDFIback to top Annotated Terms
The following terms have been associated with this transcript:
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