CXXC-type zinc finger protein

Overview


Name	CXXC-type zinc finger protein
Smed ID	SMED30016358
Length (bp)	2261

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of CXXC-type zinc finger protein (SMED30016358) t-SNE clustered cells

Violin plots show distribution of expression levels for CXXC-type zinc finger protein (SMED30016358) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of CXXC-type zinc finger protein (SMED30016358) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for CXXC-type zinc finger protein (SMED30016358) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016358

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
neoblast	SMED30016358	SMESG000025408.1	dd_Smed_v4_4714_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Human
Match: CXXC1 (CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC:24343])

HSP 1 Score: 62.7734 bits (151), Expect = 1.712e-11
Identity = 28/64 (43.75%), Postives = 42/64 (65.62%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLR 373
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+  K++R R  N R
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRH-KKSRERDGNER 97

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Human
Match: CXXC1 (CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC:24343])

HSP 1 Score: 63.5438 bits (153), Expect = 1.368e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+  K
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKK 88

HSP 2 Score: 23.483 bits (49), Expect = 1.368e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Human
Match: CXXC1 (CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC:24343])

HSP 1 Score: 63.5438 bits (153), Expect = 1.391e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+  K
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKK 88

HSP 2 Score: 23.483 bits (49), Expect = 1.391e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Human
Match: CXXC1 (CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC:24343])

HSP 1 Score: 63.5438 bits (153), Expect = 1.421e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+  K
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKK 88

HSP 2 Score: 23.483 bits (49), Expect = 1.421e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Human
Match: CXXC1 (CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC:24343])

HSP 1 Score: 63.1586 bits (152), Expect = 1.492e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+  K
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKK 88

HSP 2 Score: 23.483 bits (49), Expect = 1.492e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Fly
Match: Cfp1 (gene:FBgn0030121 transcript:FBtr0071327)

HSP 1 Score: 64.3142 bits (155), Expect = 4.758e-13
Identity = 23/52 (44.23%), Postives = 35/52 (67.31%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++ CD CEEWYHGDCI +T K+A +IK+++C  C   NP L+  ++ +   R
Sbjct:   74 MIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTIFRLVATER 125

HSP 2 Score: 30.0314 bits (66), Expect = 4.758e-13
Identity = 14/21 (66.67%), Postives = 17/21 (80.95%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            K ED+  YCICRSSD +RFM+
Sbjct:   56 KQEDQA-YCICRSSDCSRFMI 75

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Fly
Match: Cfp1 (gene:FBgn0030121 transcript:FBtr0302964)

HSP 1 Score: 64.3142 bits (155), Expect = 5.209e-13
Identity = 23/52 (44.23%), Postives = 35/52 (67.31%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++ CD CEEWYHGDCI +T K+A +IK+++C  C   NP L+  ++ +   R
Sbjct:   54 MIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTIFRLVATER 105

HSP 2 Score: 30.0314 bits (66), Expect = 5.209e-13
Identity = 14/21 (66.67%), Postives = 17/21 (80.95%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            K ED+  YCICRSSD +RFM+
Sbjct:   36 KQEDQA-YCICRSSDCSRFMI 55

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Fly
Match: CG17440 (gene:FBgn0030120 transcript:FBtr0071328)

HSP 1 Score: 62.3882 bits (150), Expect = 4.483e-12
Identity = 23/52 (44.23%), Postives = 33/52 (63.46%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++ CD CEEWYHGDCI +T K A +IK ++C  C   NP L+  ++ +   R
Sbjct:   52 MIGCDGCEEWYHGDCIEITEKDAEHIKNYYCRRCKKENPELQTIFRLVATER 103

HSP 2 Score: 28.8758 bits (63), Expect = 4.483e-12
Identity = 11/14 (78.57%), Postives = 13/14 (92.86%), Query Frame = 1

Query:  124 YCICRSSDGTRFMM 165
            YCICRSSD +RFM+
Sbjct:   40 YCICRSSDCSRFMI 53

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Fly
Match: CG3347 (gene:FBgn0031513 transcript:FBtr0340587)

HSP 1 Score: 51.2174 bits (121), Expect = 2.681e-6
Identity = 21/60 (35.00%), Postives = 32/60 (53.33%), Query Frame = 2

Query:  155 DL*CNFHN*NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            D+ C     ++N  ++ CDNC EW+HGDCI +          ++C  C  +NP L+  YK
Sbjct:   21 DVYCICRQSHINGFMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTECFRKNPLLKCTYK 80

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Fly
Match: CG3347 (gene:FBgn0031513 transcript:FBtr0301033)

HSP 1 Score: 51.2174 bits (121), Expect = 2.681e-6
Identity = 21/60 (35.00%), Postives = 32/60 (53.33%), Query Frame = 2

Query:  155 DL*CNFHN*NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            D+ C     ++N  ++ CDNC EW+HGDCI +          ++C  C  +NP L+  YK
Sbjct:   21 DVYCICRQSHINGFMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTECFRKNPLLKCTYK 80

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Zebrafish
Match: cxxc1b (CXXC finger protein 1b [Source:ZFIN;Acc:ZDB-GENE-030728-4])

HSP 1 Score: 66.6254 bits (161), Expect = 8.037e-13
Identity = 28/57 (49.12%), Postives = 39/57 (68.42%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++N  ++ CDNC EW+HG CINVT K A  I+ ++C  C  R+PSL I Y+  K+NR
Sbjct:   35 DINCFMIGCDNCNEWFHGHCINVTEKMAKAIREWYCQQCRARDPSLSIRYR--KKNR 89

HSP 2 Score: 27.335 bits (59), Expect = 8.037e-13
Identity = 12/22 (54.55%), Postives = 15/22 (68.18%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +K E+  LYCICR SD   FM+
Sbjct:   20 EKGENAPLYCICRKSDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Zebrafish
Match: cxxc1b (CXXC finger protein 1b [Source:ZFIN;Acc:ZDB-GENE-030728-4])

HSP 1 Score: 66.6254 bits (161), Expect = 8.362e-13
Identity = 28/57 (49.12%), Postives = 39/57 (68.42%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++N  ++ CDNC EW+HG CINVT K A  I+ ++C  C  R+PSL I Y+  K+NR
Sbjct:   34 DINCFMIGCDNCNEWFHGHCINVTEKMAKAIREWYCQQCRARDPSLSIRYR--KKNR 88

HSP 2 Score: 27.335 bits (59), Expect = 8.362e-13
Identity = 12/22 (54.55%), Postives = 15/22 (68.18%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +K E+  LYCICR SD   FM+
Sbjct:   19 EKGENAPLYCICRKSDINCFMI 40

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Zebrafish
Match: cxxc1a (CXXC finger protein 1a [Source:ZFIN;Acc:ZDB-GENE-040426-1142])

HSP 1 Score: 58.151 bits (139), Expect = 2.667e-8
Identity = 20/54 (37.04%), Postives = 37/54 (68.52%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CD+C EW+HGDCI ++ K A  I+ ++C  C  ++ +LE++Y+  K
Sbjct:   33 DINCFMIGCDSCSEWFHGDCIKISEKTAKTIRVWYCEKCRSKDETLEVKYRPKK 86

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Xenopus
Match: CXXC1 (CXXC finger protein 1 [Source:NCBI gene;Acc:613066])

HSP 1 Score: 62.3882 bits (150), Expect = 3.799e-10
Identity = 23/51 (45.10%), Postives = 36/51 (70.59%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            ++N  ++ CDNC EW+HG CIN+T K A  I+ ++C  C  ++P LEI+Y+
Sbjct:   30 DINCFMIGCDNCNEWFHGHCINITEKMAKAIREWYCVQCRDKHPHLEIKYR 80

HSP 2 Score: 23.0978 bits (48), Expect = 3.799e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   15 EDGENAPVYCICRKPDINCFMI 36

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Xenopus
Match: CXXC1 (CXXC finger protein 1 [Source:NCBI gene;Acc:613066])

HSP 1 Score: 62.3882 bits (150), Expect = 3.936e-10
Identity = 23/51 (45.10%), Postives = 36/51 (70.59%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            ++N  ++ CDNC EW+HG CIN+T K A  I+ ++C  C  ++P LEI+Y+
Sbjct:   30 DINCFMIGCDNCNEWFHGHCINITEKMAKAIREWYCVQCRDKHPHLEIKYR 80

HSP 2 Score: 23.0978 bits (48), Expect = 3.936e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   15 EDGENAPVYCICRKPDINCFMI 36

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Xenopus
Match: CXXC1 (CXXC finger protein 1 [Source:NCBI gene;Acc:613066])

HSP 1 Score: 62.3882 bits (150), Expect = 4.505e-10
Identity = 23/51 (45.10%), Postives = 36/51 (70.59%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            ++N  ++ CDNC EW+HG CIN+T K A  I+ ++C  C  ++P LEI+Y+
Sbjct:   20 DINCFMIGCDNCNEWFHGHCINITEKMAKAIREWYCVQCRDKHPHLEIKYR 70

HSP 2 Score: 23.0978 bits (48), Expect = 4.505e-10
Identity = 9/20 (45.00%), Postives = 12/20 (60.00%), Query Frame = 1

Query:  106 SEDEILYCICRSSDGTRFMM 165
             E+  +YCICR  D   FM+
Sbjct:    7 GENAPVYCICRKPDINCFMI 26

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Xenopus
Match: CXXC1 (CXXC finger protein 1 [Source:NCBI gene;Acc:613066])

HSP 1 Score: 60.4622 bits (145), Expect = 6.876e-9
Identity = 22/46 (47.83%), Postives = 33/46 (71.74%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            ++ CDNC EW+HG CIN+T K A  I+ ++C  C  ++P LEI+Y+
Sbjct:    1 MIGCDNCNEWFHGHCINITEKMAKAIREWYCVQCRDKHPHLEIKYR 46

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Mouse
Match: Cxxc1 (CXXC finger 1 (PHD domain) [Source:MGI Symbol;Acc:MGI:1921572])

HSP 1 Score: 63.1586 bits (152), Expect = 1.292e-10
Identity = 23/51 (45.10%), Postives = 35/51 (68.63%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYR 85

HSP 2 Score: 23.483 bits (49), Expect = 1.292e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. UniProt/SwissProt
Match: sp|Q9W352|CXXC1_DROME (CXXC-type zinc finger protein 1 OS=Drosophila melanogaster OX=7227 GN=Cfp1 PE=1 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 3.643e-12
Identity = 23/52 (44.23%), Postives = 35/52 (67.31%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++ CD CEEWYHGDCI +T K+A +IK+++C  C   NP L+  ++ +   R
Sbjct:   74 MIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTIFRLVATER 125

HSP 2 Score: 30.0314 bits (66), Expect = 3.643e-12
Identity = 14/21 (66.67%), Postives = 17/21 (80.95%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            K ED+  YCICRSSD +RFM+
Sbjct:   56 KQEDQA-YCICRSSDCSRFMI 75

[Close]

BLAST of CXXC-type zinc finger protein vs. UniProt/SwissProt
Match: sp|Q9P0U4|CXXC1_HUMAN (CXXC-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=CXXC1 PE=1 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 6.575e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+  K
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKK 88

HSP 2 Score: 23.483 bits (49), Expect = 6.575e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. UniProt/SwissProt
Match: sp|Q5EA28|CXXC1_BOVIN (CXXC-type zinc finger protein 1 OS=Bos taurus OX=9913 GN=CXXC1 PE=2 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 6.682e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+  K
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKK 88

HSP 2 Score: 23.483 bits (49), Expect = 6.682e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. UniProt/SwissProt
Match: sp|Q9CWW7|CXXC1_MOUSE (CXXC-type zinc finger protein 1 OS=Mus musculus OX=10090 GN=Cxxc1 PE=1 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 7.861e-10
Identity = 23/51 (45.10%), Postives = 35/51 (68.63%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYK 334
            ++N  ++ CDNC EW+HGDCI +T K A  I+ ++C  C  ++P LEI Y+
Sbjct:   35 DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYR 85

HSP 2 Score: 23.483 bits (49), Expect = 7.861e-10
Identity = 9/22 (40.91%), Postives = 13/22 (59.09%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            +  E+  +YCICR  D   FM+
Sbjct:   20 ENGENAPIYCICRKPDINCFMI 41

[Close]

BLAST of CXXC-type zinc finger protein vs. TrEMBL
Match: A0A0X3Q4U4 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR99153 PE=4 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 1.218e-31
Identity = 145/521 (27.83%), Postives = 214/521 (41.07%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKEN-------RPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIET--SGFVPTLN---------------------DCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQ----------KGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGG-GNSTSL-RRGLNTTTYFGGESLEVTNGTSYR----YRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQ---LSPHQCQYAEDSEEDMMIPGETMSPTNGQR--RTVVDSEHRNYTSYNXXXXXXXXRIGKNVVNNDTRKY---QYGLSYPDHLYCKHHRFYNWHS 1597
            ++ACDNCEEWYHG+CINV+PKQA  I+ F+C +C  ++P+L IE+K    N       R R  N+   +  +   SEDE +A                +    RKR R       K +   + R RP        DE+++D++E   S F    +                       PP+S D+ + N  V+  +R       +SRN N             CG C+GCK T +CG CE C+        SR  C+ R C+             +   + S   S L DF+                   +D     +R    S   K    +GSKMRRGDHLPGG G+S ++  RGL+      G   +VT   S      Y   P  R  RN ++  +            I  N++ + G    + P   Q + +S+ED+++P   M P +G       + S + +     + +    QR       N  ++     Y L YPDHLYCKHHR ++  S
Sbjct:   39 MIACDNCEEWYHGECINVSPKQAECIQTFYCQICRDKDPNLRIEFKNEHPNGKQNYAGRQRAANMSSPVAGV---SEDETEA---------------YHSSRSRKRGR-------KHSNPLQSRARPANNMPVRGDESSDDDMEVTPSQFASPSSAYSQSNSIQGSYSQRGSKFGRATPPMSFDN-SSNADVQPHWR-----RVHSRNPN----------PSQCGECEGCKRTDDCGSCEVCRSPKFKQGRSRQRCIYRTCIGMDFAPSRRIGRVRPSSKISPTQSQLSDFD---------------YDSHFDDYSSSRRFI--SGPPKSGAAMGSKMRRGDHLPGGLGSSRNIPDRGLDPHFPRRGSYTDVTLFDSGEFGGSYGVSPAQRGDRNGSSRYSASHHLHTDMEPHIMRNSNELLGHGENIGPGDPQASYESDEDVVLP--EMRPCSGPACSNPAIRSRYCSEECQLRHESNVMQRPHPASRFNGAKEQVLTPYALPYPDHLYCKHHRMHSSQS 499

HSP 2 Score: 28.4906 bits (62), Expect = 1.218e-31
Identity = 11/18 (61.11%), Postives = 13/18 (72.22%), Query Frame = 1

Query:  112 DEILYCICRSSDGTRFMM 165
            DE +YCICRSS    FM+
Sbjct:   23 DEPIYCICRSSQCDTFMI 40

[Close]

BLAST of CXXC-type zinc finger protein vs. TrEMBL
Match: A0A0X3PWF6 (CXXC-type zinc finger protein 1 OS=Schistocephalus solidus OX=70667 GN=CXXC1 PE=4 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 4.958e-26
Identity = 127/455 (27.91%), Postives = 187/455 (41.10%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKEN-------RPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIET--SGFVPTLN---------------------DCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQ----------KGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGG-GNSTSL-RRGLNTTTYFGGESLEVTNGTSYR----YRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQ---LSPHQCQYAEDSEEDMMIPGETMSPTNG 1414
            ++ACDNCEEWYHG+CINV+PKQA  I+ F+C +C  ++P+L IE+K    N       R R  N+   +  +   SEDE +A                +    RKR R       K +   + R RP        DE+++D++E   S F    +                       PP+S D+ + N  V+  +R       +SRN N             CG C+GCK T +CG CE C+        SR  C+ R C+             +   + S   S L DF+                   +D     +R    S   K    +GSKMRRGDHLPGG G+S ++  RGL+      G   +VT   S      Y   P  R  RN ++  +            I  N++ + G    + P   Q + +S+ED+++P   M P +G
Sbjct:    1 MIACDNCEEWYHGECINVSPKQAECIQTFYCQICRDKDPNLRIEFKNEHPNGKQNYAGRQRAANMSSPVAGV---SEDETEA---------------YHSSRSRKRGR-------KHSNPLQSRARPANNMPVRGDESSDDDMEVTPSQFASPSSAYSQSNSIQGSYSQRGSKFGRATPPMSFDN-SSNADVQPHWR-----RVHSRNPN----------PSQCGECEGCKRTDDCGSCEVCRSPKFKQGRSRQRCIYRTCIGMDFAPSRRIGRVRPSSKISPTQSQLSDFD---------------YDSHFDDYSSSRRFI--SGPPKSGAAMGSKMRRGDHLPGGLGSSRNIPDRGLDPHFPRRGSYTDVTLFDSGEFGGSYGVSPAQRGDRNGSSRYSASHHLHTDMEPHIMRNSNELLGHGENIGPGDPQASYESDEDVVLP--EMRPCSG 395

[Close]

BLAST of CXXC-type zinc finger protein vs. TrEMBL
Match: A0A3P7EG80 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS2491 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 5.047e-26
Identity = 143/549 (26.05%), Postives = 214/549 (38.98%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDE--IETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNN-----NYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCV--KRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSG-----------EYDIGEIRQ-------------------RLTNQSNT----------------------NKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGG--ESLEVTNGTSY--RYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSV---SGQLSPHQCQYAEDSEEDMMIPGETMSPTNG-----------------QRRTVVDSEHRNYTSYNXXXXXXXXRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYN 1588
            ++ACD CEEWYHG+CINVTPKQA  I++F+C  C    P L+IE+K    N       R +   I+ S+  + D       + +     SK+ + ++ +SR      V SA +  R G           E++EDE  ++ S F    +      I       Y  +S   ++   +Y  +N      +    S +   + CG CD CK   NCG CE C+        SR  C+   ++C+       Q  +Q S    +    GE      EN ++ G           ++  G  RQ                   ++++QS+                        K    +GSKMRRGDHLPGGG   S R   +      G    L + + + +   Y   PT+R  RN ++      SR     +++  N   +      L+P       DS+ED+++P   M P  G                 Q R   DS +R +TS                   D  K  Y L YPDHLYC+HHR Y+
Sbjct:   38 MIACDACEEWYHGECINVTPKQAECIQKFYCQACRDEKPELQIEFKPDHMNGRHSYGSRHRPADISCSTMGDADDYADRFGSIQSRKRSSKHSQPLQPKSR-----RVPSA-VPTRLG-----------ESSEDEFDLDHSQFASPSSSYSQSHI-----GPYSSRSKYGRVTLPTYENSNCVDFQQWRRPFSRNRSPQPCGECDSCKTRDNCGTCEVCRSPKFKQARSRQHCLLKGKMCLANDSDFQQPWRQQSSRGRYAPPCGEC-----ENCKTKGNCGTCEVCRSPKFKQGRSRQYCLYRAKICLGNGLQRQSSKISSQSHLPDPDYETHFDDFASSTRFSSGGRKGAPMIGSKMRRGDHLPGGGIGPSGRLAHDPQFPRRGPHSDLNLLDSSDFVDAYSISPTHRTDRNGSSRFVGPNSRQNDLDSRVMRNVGGIMDTDDLLAPADAPPNYDSDEDVVLP--EMRPCAGPACSKPAIRSRYCSEECQLRHESDSINRMHTSSRCSSV------------KDQIKTPYALPYPDHLYCRHHRMYS 545

HSP 2 Score: 24.6386 bits (52), Expect = 5.047e-26
Identity = 11/21 (52.38%), Postives = 14/21 (66.67%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            +  DE +YCICRSS    FM+
Sbjct:   19 EPSDEPVYCICRSSVCDTFMI 39

[Close]

BLAST of CXXC-type zinc finger protein vs. TrEMBL
Match: A0A0X3PAV2 (CXXC-type domain-containing protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR99153 PE=4 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 5.072e-26
Identity = 127/455 (27.91%), Postives = 187/455 (41.10%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKEN-------RPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIET--SGFVPTLN---------------------DCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQ----------KGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGG-GNSTSL-RRGLNTTTYFGGESLEVTNGTSYR----YRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQ---LSPHQCQYAEDSEEDMMIPGETMSPTNG 1414
            ++ACDNCEEWYHG+CINV+PKQA  I+ F+C +C  ++P+L IE+K    N       R R  N+   +  +   SEDE +A                +    RKR R       K +   + R RP        DE+++D++E   S F    +                       PP+S D+ + N  V+  +R       +SRN N             CG C+GCK T +CG CE C+        SR  C+ R C+             +   + S   S L DF+                   +D     +R    S   K    +GSKMRRGDHLPGG G+S ++  RGL+      G   +VT   S      Y   P  R  RN ++  +            I  N++ + G    + P   Q + +S+ED+++P   M P +G
Sbjct:    1 MIACDNCEEWYHGECINVSPKQAECIQTFYCQICRDKDPNLRIEFKNEHPNGKQNYAGRQRAANMSSPVAGV---SEDETEA---------------YHSSRSRKRGR-------KHSNPLQSRARPANNMPVRGDESSDDDMEVTPSQFASPSSAYSQSNSIQGSYSQRGSKFGRATPPMSFDN-SSNADVQPHWR-----RVHSRNPN----------PSQCGECEGCKRTDDCGSCEVCRSPKFKQGRSRQRCIYRTCIGMDFAPSRRIGRVRPSSKISPTQSQLSDFD---------------YDSHFDDYSSSRRFI--SGPPKSGAAMGSKMRRGDHLPGGLGSSRNIPDRGLDPHFPRRGSYTDVTLFDSGEFGGSYGVSPAQRGDRNGSSRYSASHHLHTDMEPHIMRNSNELLGHGENIGPGDPQASYESDEDVVLP--EMRPCSG 395

[Close]

BLAST of CXXC-type zinc finger protein vs. TrEMBL
Match: A0A0R3WP16 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 5.260e-26
Identity = 143/549 (26.05%), Postives = 214/549 (38.98%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDE--IETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNN-----NYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCV--KRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSG-----------EYDIGEIRQ-------------------RLTNQSNT----------------------NKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGG--ESLEVTNGTSY--RYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSV---SGQLSPHQCQYAEDSEEDMMIPGETMSPTNG-----------------QRRTVVDSEHRNYTSYNXXXXXXXXRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYN 1588
            ++ACD CEEWYHG+CINVTPKQA  I++F+C  C    P L+IE+K    N       R +   I+ S+  + D       + +     SK+ + ++ +SR      V SA +  R G           E++EDE  ++ S F    +      I       Y  +S   ++   +Y  +N      +    S +   + CG CD CK   NCG CE C+        SR  C+   ++C+       Q  +Q S    +    GE      EN ++ G           ++  G  RQ                   ++++QS+                        K    +GSKMRRGDHLPGGG   S R   +      G    L + + + +   Y   PT+R  RN ++      SR     +++  N   +      L+P       DS+ED+++P   M P  G                 Q R   DS +R +TS                   D  K  Y L YPDHLYC+HHR Y+
Sbjct:   38 MIACDACEEWYHGECINVTPKQAECIQKFYCQACRDEKPELQIEFKPDHMNGRHSYGSRHRPADISCSTMGDADDYADRFGSIQSRKRSSKHSQPLQPKSR-----RVPSA-VPTRLG-----------ESSEDEFDLDHSQFASPSSSYSQSHI-----GPYSSRSKYGRVTLPTYENSNCVDFQQWRRPFSRNRSPQPCGECDSCKTRDNCGTCEVCRSPKFKQARSRQHCLLKGKMCLANDSDFQQPWRQQSSRGRYAPPCGEC-----ENCKTKGNCGTCEVCRSPKFKQGRSRQYCLYRAKICLGNGLQRQSSKISSQSHLPDPDYETHFDDFASSTRFSSGGRKGAPMIGSKMRRGDHLPGGGIGPSGRLAHDPQFPRRGPHSDLNLLDSSDFVDAYSISPTHRTDRNGSSRFVGPNSRQNDLDSRVMRNVGGIMDTDDLLAPADAPPNYDSDEDVVLP--EMRPCAGPACSKPAIRSRYCSEECQLRHESDSINRMHTSSRCSSV------------KDQIKTPYALPYPDHLYCRHHRMYS 545

HSP 2 Score: 24.6386 bits (52), Expect = 5.260e-26
Identity = 11/21 (52.38%), Postives = 14/21 (66.67%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            +  DE +YCICRSS    FM+
Sbjct:   19 EPSDEPVYCICRSSVCDTFMI 39

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Cavefish
Match: cxxc1b (CXXC-type zinc finger protein 1-like [Source:NCBI gene;Acc:103045901])

HSP 1 Score: 65.4698 bits (158), Expect = 1.787e-11
Identity = 27/57 (47.37%), Postives = 42/57 (73.68%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++N  ++ CD+C EW+HG CINVT K A  I+ ++C  C  ++PSLEI+Y++ K+NR
Sbjct:   34 DINCFMIGCDSCNEWFHGHCINVTEKMAKAIREWYCKRCQDKDPSLEIKYRS-KKNR 89

HSP 2 Score: 23.8682 bits (50), Expect = 1.787e-11
Identity = 10/21 (47.62%), Postives = 13/21 (61.90%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            + E+  LYCICR  D   FM+
Sbjct:   20 EEENAPLYCICRKPDINCFMI 40

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Cavefish
Match: cxxc1b (CXXC-type zinc finger protein 1-like [Source:NCBI gene;Acc:103045901])

HSP 1 Score: 65.0846 bits (157), Expect = 1.962e-11
Identity = 27/57 (47.37%), Postives = 42/57 (73.68%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENR 352
            ++N  ++ CD+C EW+HG CINVT K A  I+ ++C  C  ++PSLEI+Y++ K+NR
Sbjct:   27 DINCFMIGCDSCNEWFHGHCINVTEKMAKAIREWYCKRCQDKDPSLEIKYRS-KKNR 82

HSP 2 Score: 24.2534 bits (51), Expect = 1.962e-11
Identity = 10/21 (47.62%), Postives = 13/21 (61.90%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            + E+  LYCICR  D   FM+
Sbjct:   13 EEENAPLYCICRKPDINCFMI 33

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Cavefish
Match: cxxc1a (CXXC-type zinc finger protein 1 [Source:NCBI gene;Acc:103028330])

HSP 1 Score: 58.9214 bits (141), Expect = 6.765e-9
Identity = 22/54 (40.74%), Postives = 37/54 (68.52%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CD+C EW+HGDCI ++ K A  I+ ++C  C  ++ SLEI+Y+  K
Sbjct:   31 DINCFMIGCDSCNEWFHGDCIFISEKMAKTIRVWYCERCRSKDGSLEIKYRPKK 84

HSP 2 Score: 21.557 bits (44), Expect = 6.765e-9
Identity = 8/20 (40.00%), Postives = 13/20 (65.00%), Query Frame = 1

Query:  106 SEDEILYCICRSSDGTRFMM 165
            +++  +YCICR  D   FM+
Sbjct:   18 NQNAPVYCICRKPDINCFMI 37

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Nematostella
Match: EDO32761 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU49])

HSP 1 Score: 53.9138 bits (128), Expect = 6.048e-9
Identity = 19/46 (41.30%), Postives = 30/46 (65.22%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSL 319
            N +  ++ CD+C+EW+HGDCI +    A  I++F+C  C+  NP L
Sbjct:   21 NTDRFMIGCDDCDEWFHGDCIGILQGDAQMIRKFYCKPCLECNPEL 66

HSP 2 Score: 25.0238 bits (53), Expect = 6.048e-9
Identity = 9/15 (60.00%), Postives = 12/15 (80.00%), Query Frame = 1

Query:  121 LYCICRSSDGTRFMM 165
            +YCICR S+  RFM+
Sbjct:   13 VYCICRQSNTDRFMI 27

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Nematostella
Match: EDO44903 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUH2])

HSP 1 Score: 42.3578 bits (98), Expect = 1.890e-6
Identity = 13/33 (39.39%), Postives = 21/33 (63.64%), Query Frame = 2

Query:  200 LACDNCEEWYHGDCINVTPKQANNIKRFFCHLC 298
            + CD C  W+HG C+N+TP++A  +  + C  C
Sbjct:  330 VGCDLCANWFHGACVNITPEEAAAMDHWSCKDC 362

HSP 2 Score: 28.1054 bits (61), Expect = 1.890e-6
Identity = 12/19 (63.16%), Postives = 13/19 (68.42%), Query Frame = 1

Query:  106 SEDEILYCICRSS-DGTRF 159
            SED  LYCIC+   D TRF
Sbjct:  310 SEDTTLYCICKKPYDATRF 328

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Medaka
Match: cxxc1b (CXXC finger protein 1 [Source:NCBI gene;Acc:101158437])

HSP 1 Score: 67.3958 bits (163), Expect = 3.515e-12
Identity = 28/66 (42.42%), Postives = 46/66 (69.70%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQ 379
            ++N  ++ CDNC EW+HG CI++T K A  I+ ++C  C  RNP+LE++Y++ K+NR +   L +Q
Sbjct:   49 DINCFMIGCDNCNEWFHGHCISITEKMAKAIQEWYCMRCRDRNPTLEVKYRS-KKNRDKDAELERQ 113

HSP 2 Score: 24.2534 bits (51), Expect = 3.515e-12
Identity = 10/21 (47.62%), Postives = 13/21 (61.90%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            + E+  LYCICR  D   FM+
Sbjct:   35 EGENAPLYCICRKPDINCFMI 55

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Medaka
Match: cxxc1b (CXXC finger protein 1 [Source:NCBI gene;Acc:101158437])

HSP 1 Score: 67.3958 bits (163), Expect = 3.664e-12
Identity = 28/66 (42.42%), Postives = 46/66 (69.70%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQ 379
            ++N  ++ CDNC EW+HG CI++T K A  I+ ++C  C  RNP+LE++Y++ K+NR +   L +Q
Sbjct:   34 DINCFMIGCDNCNEWFHGHCISITEKMAKAIQEWYCMRCRDRNPTLEVKYRS-KKNRDKDAELERQ 98

HSP 2 Score: 24.2534 bits (51), Expect = 3.664e-12
Identity = 10/21 (47.62%), Postives = 13/21 (61.90%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            + E+  LYCICR  D   FM+
Sbjct:   20 EGENAPLYCICRKPDINCFMI 40

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Medaka
Match: cxxc1b (CXXC finger protein 1 [Source:NCBI gene;Acc:101158437])

HSP 1 Score: 67.3958 bits (163), Expect = 3.818e-12
Identity = 28/66 (42.42%), Postives = 46/66 (69.70%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQ 379
            ++N  ++ CDNC EW+HG CI++T K A  I+ ++C  C  RNP+LE++Y++ K+NR +   L +Q
Sbjct:   32 DINCFMIGCDNCNEWFHGHCISITEKMAKAIQEWYCMRCRDRNPTLEVKYRS-KKNRDKDAELERQ 96

HSP 2 Score: 24.2534 bits (51), Expect = 3.818e-12
Identity = 10/20 (50.00%), Postives = 12/20 (60.00%), Query Frame = 1

Query:  106 SEDEILYCICRSSDGTRFMM 165
             E+  LYCICR  D   FM+
Sbjct:   19 GENAPLYCICRKPDINCFMI 38

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Medaka
Match: cxxc1a (CXXC-type zinc finger protein 1 [Source:NCBI gene;Acc:101175046])

HSP 1 Score: 59.6918 bits (143), Expect = 6.717e-9
Identity = 22/54 (40.74%), Postives = 38/54 (70.37%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CD+C EW+HGDCI V+ + A +I+ +FC  C  ++ SLE++Y+  K
Sbjct:   38 DINCFMIGCDSCSEWFHGDCIGVSERAAKSIRVWFCLSCREKDSSLELKYRQKK 91

HSP 2 Score: 20.7866 bits (42), Expect = 6.717e-9
Identity = 8/21 (38.10%), Postives = 13/21 (61.90%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            +S +  +YC+CR  D   FM+
Sbjct:   24 ESPNTPVYCVCRRPDINCFMI 44

[Close]

BLAST of CXXC-type zinc finger protein vs. Ensembl Medaka
Match: cxxc1a (CXXC-type zinc finger protein 1 [Source:NCBI gene;Acc:101175046])

HSP 1 Score: 59.6918 bits (143), Expect = 7.593e-9
Identity = 22/54 (40.74%), Postives = 38/54 (70.37%), Query Frame = 2

Query:  182 NLNARILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIK 343
            ++N  ++ CD+C EW+HGDCI V+ + A +I+ +FC  C  ++ SLE++Y+  K
Sbjct:   48 DINCFMIGCDSCSEWFHGDCIGVSERAAKSIRVWFCLSCREKDSSLELKYRQKK 101

HSP 2 Score: 20.7866 bits (42), Expect = 7.593e-9
Identity = 8/21 (38.10%), Postives = 13/21 (61.90%), Query Frame = 1

Query:  103 KSEDEILYCICRSSDGTRFMM 165
            +S +  +YC+CR  D   FM+
Sbjct:   34 ESPNTPVYCVCRRPDINCFMI 54

[Close]

BLAST of CXXC-type zinc finger protein vs. Planmine SMEST
Match: SMESG000025408.1 (SMESG000025408.1)

HSP 1 Score: 1233.39 bits (3190), Expect = 0.000e+0
Identity = 627/631 (99.37%), Postives = 630/631 (99.84%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHRNYTSYNXXXXXXXXRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIAIESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV 2089
            ++ACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLSSSSTPEKSFSPSKNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHR YTSYNQQQQQQQQRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIA+ESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV
Sbjct:   65 MIACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLSSSSTPEKSFSPSKNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHRTYTSYNQQQQQQQQRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIAVESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV 695

HSP 2 Score: 83.1889 bits (204), Expect = 3.055e-16
Identity = 54/55 (98.18%), Postives = 55/55 (100.00%), Query Frame = 1

Query:    1 VYLQSCFTFVSHYYREMTXXXXXXXXXXXXXXXQKSEDEILYCICRSSDGTRFMM 165
            VYLQSCFTFVSHYYREMTRKRSKIRSKTRSDSSQKSEDEILYCICRSSDGTRFM+
Sbjct:   12 VYLQSCFTFVSHYYREMTRKRSKIRSKTRSDSSQKSEDEILYCICRSSDGTRFMI 66

[Close]

BLAST of CXXC-type zinc finger protein vs. Planmine SMEST
Match: SMESG000025408.1 (SMESG000025408.1)

HSP 1 Score: 1232.24 bits (3187), Expect = 0.000e+0
Identity = 627/631 (99.37%), Postives = 630/631 (99.84%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHRNYTSYNXXXXXXXXRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIAIESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV 2089
            ++ACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLSSSSTPEKSFSPSKNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHR YTSYNQQQQQQQQRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIA+ESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV
Sbjct:   38 MIACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLSSSSTPEKSFSPSKNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHRTYTSYNQQQQQQQQRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIAVESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV 668

HSP 2 Score: 49.6766 bits (117), Expect = 9.137e-6
Identity = 21/22 (95.45%), Postives = 22/22 (100.00%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            QKSEDEILYCICRSSDGTRFM+
Sbjct:   18 QKSEDEILYCICRSSDGTRFMI 39

[Close]

BLAST of CXXC-type zinc finger protein vs. Planmine SMEST
Match: SMESG000025408.1 (SMESG000025408.1)

HSP 1 Score: 1217.22 bits (3148), Expect = 0.000e+0
Identity = 612/631 (96.99%), Postives = 616/631 (97.62%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLXXXXXXXXXXXXXXNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENMYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHRNYTSYNXXXXXXXXRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIAIESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV 2089
            ++ACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLSSSSTPEKSFSPSKNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTEN+Y              SRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHR YTSYNQQQQQQQQRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIA+ESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV
Sbjct:   38 MIACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPRLPNLRQQIKKINFSSEDENDADLSSSSTPEKSFSPSKNKRTIRKRSRPSISESVKSATIKKRRGRPKEKPDDYDDEATEDEIETSGFVPTLNDCPPISIDDQTENIY--------------SRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKCEPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETGFSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGNSTSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRSRPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRRTVVDSEHRTYTSYNQQQQQQQQRIGKNVVNNDTRKYQYGLSYPDHLYCKHHRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQLPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYSESSQAYPIIDLNQQITSGIPLNSSAQIAVESNPHSTTVFSKLSTANVHRQEFYTINDEDDLEINWPKETVNV 654

HSP 2 Score: 49.6766 bits (117), Expect = 8.983e-6
Identity = 21/22 (95.45%), Postives = 22/22 (100.00%), Query Frame = 1

Query:  100 QKSEDEILYCICRSSDGTRFMM 165
            QKSEDEILYCICRSSDGTRFM+
Sbjct:   18 QKSEDEILYCICRSSDGTRFMI 39

[Close]

BLAST of CXXC-type zinc finger protein vs. Planmine SMEST
Match: SMESG000074165.1 (SMESG000074165.1)

HSP 1 Score: 76.6406 bits (187), Expect = 4.382e-16
Identity = 29/54 (53.70%), Postives = 41/54 (75.93%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKTIKENRPR 358
            ++ CD+CEEWYHGDC+N+TPKQ+  I ++FC  C  RNPSL+I+YK     +P+
Sbjct:   47 MICCDSCEEWYHGDCVNITPKQSELISKYFCLQCQKRNPSLKIQYKAGIIKKPK 100

HSP 2 Score: 27.7202 bits (60), Expect = 4.382e-16
Identity = 10/15 (66.67%), Postives = 12/15 (80.00%), Query Frame = 1

Query:  121 LYCICRSSDGTRFMM 165
            L+CICRS D  RFM+
Sbjct:   34 LWCICRSEDSERFMI 48

[Close]

BLAST of CXXC-type zinc finger protein vs. Planmine SMEST
Match: SMESG000004468.1 (SMESG000004468.1)

HSP 1 Score: 67.781 bits (164), Expect = 2.512e-15
Identity = 25/47 (53.19%), Postives = 36/47 (76.60%), Query Frame = 2

Query:  197 ILACDNCEEWYHGDCINVTPKQANNIKRFFCHLCIGRNPSLEIEYKT 337
            ++ CD CEEWYHGDCIN+TPK+A +I +++C  C  R P+L+  YK+
Sbjct:   48 MICCDKCEEWYHGDCINITPKEAEHILKYYCAQCEKREPTLKSVYKS 94

HSP 2 Score: 34.2686 bits (77), Expect = 2.512e-15
Identity = 12/15 (80.00%), Postives = 15/15 (100.00%), Query Frame = 1

Query:  121 LYCICRSSDGTRFMM 165
            L+CICRSSDG+RFM+
Sbjct:   35 LWCICRSSDGSRFMI 49

The following BLAST results are available for this feature:

BLAST of CXXC-type zinc finger protein vs. Ensembl Human
BLAST of CXXC-type zinc finger protein vs. Ensembl Celegans
BLAST of CXXC-type zinc finger protein vs. Ensembl Fly
BLAST of CXXC-type zinc finger protein vs. Ensembl Zebrafish
BLAST of CXXC-type zinc finger protein vs. Ensembl Xenopus
BLAST of CXXC-type zinc finger protein vs. Ensembl Mouse
BLAST of CXXC-type zinc finger protein vs. UniProt/SwissProt
BLAST of CXXC-type zinc finger protein vs. TrEMBL
BLAST of CXXC-type zinc finger protein vs. Ensembl Cavefish
BLAST of CXXC-type zinc finger protein vs. Ensembl Sea Lamprey
BLAST of CXXC-type zinc finger protein vs. Ensembl Yeast
BLAST of CXXC-type zinc finger protein vs. Ensembl Nematostella
BLAST of CXXC-type zinc finger protein vs. Ensembl Medaka
BLAST of CXXC-type zinc finger protein vs. Planmine SMEST

BLAST of CXXC-type zinc finger protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CXXC1	1.712e-11	43.75	CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC...	[more]
CXXC1	1.368e-10	44.44	CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC...	[more]
CXXC1	1.391e-10	44.44	CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC...	[more]
CXXC1	1.421e-10	44.44	CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC...	[more]
CXXC1	1.492e-10	44.44	CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of CXXC-type zinc finger protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of CXXC-type zinc finger protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cfp1	4.758e-13	44.23	gene:FBgn0030121 transcript:FBtr0071327	[more]
Cfp1	5.209e-13	44.23	gene:FBgn0030121 transcript:FBtr0302964	[more]
CG17440	4.483e-12	44.23	gene:FBgn0030120 transcript:FBtr0071328	[more]
CG3347	2.681e-6	35.00	gene:FBgn0031513 transcript:FBtr0340587	[more]
CG3347	2.681e-6	35.00	gene:FBgn0031513 transcript:FBtr0301033	[more]

BLAST of CXXC-type zinc finger protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
cxxc1b	8.037e-13	49.12	CXXC finger protein 1b [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
cxxc1b	8.362e-13	49.12	CXXC finger protein 1b [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
cxxc1a	2.667e-8	37.04	CXXC finger protein 1a [Source:ZFIN;Acc:ZDB-GENE-0...	[more]

BLAST of CXXC-type zinc finger protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
CXXC1	3.799e-10	45.10	CXXC finger protein 1 [Source:NCBI gene;Acc:613066...	[more]
CXXC1	3.936e-10	45.10	CXXC finger protein 1 [Source:NCBI gene;Acc:613066...	[more]
CXXC1	4.505e-10	45.10	CXXC finger protein 1 [Source:NCBI gene;Acc:613066...	[more]
CXXC1	6.876e-9	47.83	CXXC finger protein 1 [Source:NCBI gene;Acc:613066...	[more]

BLAST of CXXC-type zinc finger protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Cxxc1	1.292e-10	45.10	CXXC finger 1 (PHD domain) [Source:MGI Symbol;Acc:...	[more]

BLAST of CXXC-type zinc finger protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4


Match Name	E-value	Identity	Description
sp\|Q9W352\|CXXC1_DROME	3.643e-12	44.23	CXXC-type zinc finger protein 1 OS=Drosophila mela...	[more]
sp\|Q9P0U4\|CXXC1_HUMAN	6.575e-10	44.44	CXXC-type zinc finger protein 1 OS=Homo sapiens OX...	[more]
sp\|Q5EA28\|CXXC1_BOVIN	6.682e-10	44.44	CXXC-type zinc finger protein 1 OS=Bos taurus OX=9...	[more]
sp\|Q9CWW7\|CXXC1_MOUSE	7.861e-10	45.10	CXXC-type zinc finger protein 1 OS=Mus musculus OX...	[more]

BLAST of CXXC-type zinc finger protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0X3Q4U4	1.218e-31	27.83	Uncharacterized protein OS=Schistocephalus solidus...	[more]
A0A0X3PWF6	4.958e-26	27.91	CXXC-type zinc finger protein 1 OS=Schistocephalus...	[more]
A0A3P7EG80	5.047e-26	26.05	Uncharacterized protein OS=Hydatigena taeniaeformi...	[more]
A0A0X3PAV2	5.072e-26	27.91	CXXC-type domain-containing protein (Fragment) OS=...	[more]
A0A0R3WP16	5.260e-26	26.05	Uncharacterized protein OS=Hydatigena taeniaeformi...	[more]

BLAST of CXXC-type zinc finger protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
cxxc1b	1.787e-11	47.37	CXXC-type zinc finger protein 1-like [Source:NCBI ...	[more]
cxxc1b	1.962e-11	47.37	CXXC-type zinc finger protein 1-like [Source:NCBI ...	[more]
cxxc1a	6.765e-9	40.74	CXXC-type zinc finger protein 1 [Source:NCBI gene;...	[more]

BLAST of CXXC-type zinc finger protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of CXXC-type zinc finger protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of CXXC-type zinc finger protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO32761	6.048e-9	41.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44903	1.890e-6	39.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of CXXC-type zinc finger protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cxxc1b	3.515e-12	42.42	CXXC finger protein 1 [Source:NCBI gene;Acc:101158...	[more]
cxxc1b	3.664e-12	42.42	CXXC finger protein 1 [Source:NCBI gene;Acc:101158...	[more]
cxxc1b	3.818e-12	42.42	CXXC finger protein 1 [Source:NCBI gene;Acc:101158...	[more]
cxxc1a	6.717e-9	40.74	CXXC-type zinc finger protein 1 [Source:NCBI gene;...	[more]
cxxc1a	7.593e-9	40.74	CXXC-type zinc finger protein 1 [Source:NCBI gene;...	[more]

BLAST of CXXC-type zinc finger protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000025408.1	3.055e-16	99.37	SMESG000025408.1	[more]
SMESG000025408.1	9.137e-6	99.37	SMESG000025408.1	[more]
SMESG000025408.1	8.983e-6	96.99	SMESG000025408.1	[more]
SMESG000074165.1	4.382e-16	53.70	SMESG000074165.1	[more]
SMESG000004468.1	2.512e-15	53.19	SMESG000004468.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016358 ID=SMED30016358|Name=CXXC-type zinc finger protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2261bp
GTTTATTTACAGTCATGTTTCACTTTCGTTAGCCATTATTATAGAGAAAT
GACTAGAAAAAGAAGTAAAATAAGGTCAAAAACACGGTCAGATAGCTCTC
AAAAATCAGAAGATGAAATTCTGTATTGCATTTGCCGAAGTTCAGATGGA
ACTCGATTTATGATGTAATTTTCATAATTAAAATTTAAATGCACGAATTT
TAGCATGTGATAATTGTGAAGAATGGTACCACGGAGACTGTATAAATGTC
ACACCAAAGCAAGCCAACAATATCAAGCGATTTTTTTGTCATTTATGCAT
TGGTCGAAATCCCAGTTTAGAGATTGAATACAAAACGATCAAAGAAAATC
GACCCCGACTACCAAATTTACGACAACAAATTAAAAAAATTAATTTCTCC
TCTGAAGATGAAAATGACGCCGATCTGAGTTCATCCAGTACTCCTGAAAA
ATCATTTTCACCCAGTAAAAACAAACGAACAATTCGTAAAAGATCCCGGC
CATCGATATCAGAATCTGTCAAATCAGCAACAATCAAAAAACGACGAGGT
CGACCCAAAGAAAAACCTGATGATTACGACGATGAAGCTACTGAAGACGA
AATAGAGACGTCAGGATTTGTTCCAACCTTGAATGATTGTCCACCGATCA
GTATCGATGATCAAACTGAAAACATGTATGTAAAGAAATCATTTCGCAAT
CAAATAATGAACAACAGCTATTCTCGTAATAACAATTACGGACATTCTCT
CTCAAGCGACTCGGTCAACAAAACTTGCGGAATTTGCGACGGCTGTAAAA
TGACGAGCAATTGCGGCAAATGCGAACCATGTAAGAAACAACATGGAAAT
ATCAATACATCGAGATTGACTTGCGTCAAACGACTTTGCGTTCGCGAACA
AAAGGGTCAACATCAATTCTCAAAACAGTATTCACTTTTGGAAGATTTTG
AGGGCGTTTTGGGTGAAACGGGTTTCAGTAGGCGTGAAAATATTCGTTCA
TCAGGTGAATATGACATAGGTGAAATCCGTCAACGTCTAACTAATCAATC
TAATACCAACAAAGAATTAACCACTGTCGGTAGTAAAATGCGTAGAGGAG
ATCATTTACCAGGAGGAGGCAATTCTACCTCACTTCGACGTGGCCTGAAT
ACGACAACGTATTTTGGTGGTGAATCATTGGAAGTAACGAACGGAACTTC
ATATCGATATCGTCAACAACCAACAAATCGTCTTTCACGTAATCAGAATG
CCCCGCAAAATTTACGTAGATCTAGGCCTCAGTCAGATGCTGCCCAGATT
TCTAGTAATACCTCTTCTGTTTCAGGTCAGTTATCACCTCATCAATGCCA
ATATGCTGAAGACTCCGAGGAAGATATGATGATTCCAGGTGAAACGATGT
CACCTACTAACGGTCAGAGGAGAACTGTAGTAGATTCAGAACATAGAAAC
TATACGAGCTACAACCAACAACAACAGCAGCAGCAGCAGCGAATTGGAAA
AAATGTTGTAAATAATGACACCAGAAAATACCAGTACGGCCTTAGCTATC
CTGACCATCTATATTGCAAGCACCACCGATTTTATAACTGGCATAGCAGT
GTGTCGGGTGATTCAATCTCTCCAGATATGACAAATTGTAAACCCGAAAC
CAATCTCAAATCAGACAAAGAAGGTGAAATTCTTTCCCATTCTAGACTCC
GGTCTCCCTCTCTCGAACAACAATTACCCCCTGGAAATTTTATGGTGCTC
GATCGAAACGTTAAGCAAAACCAAATTTCTTCCACTGGAATGCGTCACAA
ATCTCAAATGAAAAACAGTTCTATTTCAAACGATCGGCACGATGTCTCAG
AATCTTTTGTAAATCTCTATTCAGAATCCAGTCAAGCTTATCCTATAATT
GATCTCAATCAACAGATCACATCTGGTATACCGTTAAATTCTTCAGCCCA
AATCGCTATCGAATCCAATCCTCATTCCACCACAGTATTCTCAAAATTAT
CCACGGCTAATGTTCATCGTCAAGAGTTCTACACAATAAATGATGAAGAT
GACTTGGAAATTAATTGGCCTAAAGAGACTGTTAATGTCTAATTTATAAT
TTTCAATCTCTGTAACTGCACTTTTATTGTAATAGCTTTATTAATGTTAT
GTCATTGTTACCATTCTTGAGATGATAGTTGTTTTGTACATAATAAGTCT
GTATGAGTAGATTATCAGTTTATTTACTATAATCTTGTATTGTAAAAATA
AAGCATTGAAC

protein sequence of SMED30016358-orf-1

>SMED30016358-orf-1 ID=SMED30016358-orf-1|Name=SMED30016358-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=473bp
MYVKKSFRNQIMNNSYSRNNNYGHSLSSDSVNKTCGICDGCKMTSNCGKC
EPCKKQHGNINTSRLTCVKRLCVREQKGQHQFSKQYSLLEDFEGVLGETG
FSRRENIRSSGEYDIGEIRQRLTNQSNTNKELTTVGSKMRRGDHLPGGGN
STSLRRGLNTTTYFGGESLEVTNGTSYRYRQQPTNRLSRNQNAPQNLRRS
RPQSDAAQISSNTSSVSGQLSPHQCQYAEDSEEDMMIPGETMSPTNGQRR
TVVDSEHRNYTSYNQQQQQQQQRIGKNVVNNDTRKYQYGLSYPDHLYCKH
HRFYNWHSSVSGDSISPDMTNCKPETNLKSDKEGEILSHSRLRSPSLEQQ
LPPGNFMVLDRNVKQNQISSTGMRHKSQMKNSSISNDRHDVSESFVNLYS
ESSQAYPIIDLNQQITSGIPLNSSAQIAIESNPHSTTVFSKLSTANVHRQ
EFYTINDEDDLEINWPKETVNV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0048188	Set1C/COMPASS complex
GO:0005634	nucleus

Vocabulary: **INTERPRO**
Term	Definition
IPR013083	Znf_RING/FYVE/PHD
IPR002857	Znf_CXXC
IPR019787	Znf_PHD-finger
IPR011011	Znf_FYVE_PHD

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0008270	zinc ion binding
GO:0005515	protein binding
GO:0042393	histone binding
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0016569	covalent chromatin modification

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002857	Zinc finger, CXXC-type	PFAM	PF02008	zf-CXXC	coord: 32..72 e-value: 1.1E-6 score: 28.5
IPR002857	Zinc finger, CXXC-type	PROSITE	PS51058	ZF_CXXC	coord: 28..73 score: 10.701
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 257..275
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 245..275
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 174..229
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 174..226

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CXXC-type zinc finger protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Owlery

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