Thyroglobulin

Overview
NameThyroglobulin
Smed IDSMED30016345
Length (bp)729
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Thyroglobulin (SMED30016345) t-SNE clustered cells

Violin plots show distribution of expression levels for Thyroglobulin (SMED30016345) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Thyroglobulin (SMED30016345) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Thyroglobulin (SMED30016345) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016345

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30016345h1SMcG0020863 dd_Smed_v4_1024_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30016345h1SMcG0020863 dd_Smed_v4_1024_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30016345h1SMcG0020863 dd_Smed_v4_1024_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016345h1SMcG0020863 Contig44330uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016345h1SMcG0020863 Contig44330newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30016345h1SMcG0020863 dd_Smed_v4_1024_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30016345h1SMcG0020863 dd_Smed_v4_1024_0_1dd_Smed_v4PMID:30962434
Cote et al., 2019		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Thyroglobulin vs. Ensembl Human
Match: TG (thyroglobulin [Source:HGNC Symbol;Acc:HGNC:11764])

HSP 1 Score: 57.7658 bits (138), Expect = 5.185e-9
Identity = 35/111 (31.53%), Postives = 49/111 (44.14%), Query Frame = 2 
Query:  251 KARKGGLLGAP-------IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS--------------CTTNGSYSSVQCNG 520
            +AR   L+G+        +P C S G FLPVQC  S+CYCVD EG  I    + I +       C  +    FL  +   + +              C+T+G +  VQCNG
Sbjct:  666 RARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAIGKPKKCPTPCQLQSEQAFLRTVQALLSNSSMLPTLSDTYIPQCSTDGQWRQVQCNG 776

HSP 2 Score: 48.521 bits (114), Expect = 5.851e-6
Identity = 27/99 (27.27%), Postives = 45/99 (45.45%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINE-FANMDCKCAREQNDYFL----TGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAG 565
            +P C + G +  VQC   +C+CV+  G  +        +     DC+  R +    +     G    + +CT+ G +  VQC  S C+C D  G+A+ G
Sbjct:  617 VPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQPRCPTDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPG 715
[Close]
BLAST of Thyroglobulin vs. Ensembl Zebrafish
Match: nid2a (nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GENE-030827-2])

HSP 1 Score: 51.9878 bits (123), Expect = 1.695e-7
Identity = 38/115 (33.04%), Postives = 54/115 (46.96%), Query Frame = 2 
Query:  269 LLGAPIPKCDSNGDFLPVQCTGS--KCYCVD-----REGNNIRNYAAHINEFANMDCKCAREQN-DYFLTG-----LIGKMFS-CTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            ++GA IP+CD  G + P QC GS   C+CVD     R G      +  +N    +  K   EQ+ D   +G     ++G     C   G Y + QC+GS   C+C D  G+  AG
Sbjct:   54 VVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVRPKTQCEQHRDSLQSGNDGVPVVGAFIPQCDEEGQYRTQQCHGSTGHCWCVDNRGQERAG 168

HSP 2 Score: 48.1358 bits (113), Expect = 3.120e-6
Identity = 37/134 (27.61%), Postives = 57/134 (42.54%), Query Frame = 2 
Query:  224 NTQCFNKLNKARKG----GLLGAPIPKCDSNGDFLPVQCTGS--KCYCVD-----REGNNIRNYAAHIN--EFANMDCKCAREQN-----DYFLTGLIGKMFSCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
             TQC    +  + G     ++GA IP+CD  G +   QC GS   C+CVD     R G      +  +N  +      +C + ++     D  +  +   +  C   G Y   QC+GS   C+C D  G+  AG
Sbjct:  111 KTQCEQHRDSLQSGNDGVPVVGAFIPQCDEEGQYRTQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVRPKTQCEQHRDSLQSGDGGVPAVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDSRGQERAG 244
[Close]
BLAST of Thyroglobulin vs. Ensembl Zebrafish
Match: nid2a (nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GENE-030827-2])

HSP 1 Score: 49.2914 bits (116), Expect = 1.010e-6
Identity = 42/136 (30.88%), Postives = 57/136 (41.91%), Query Frame = 2 
Query:  269 LLGAPIPKCDSNGDFLPVQCTGS--KCYCVDREGNN-----------IRNYAAHINEFANMDCKCARE--QNDYFLTGLIGKMFS-CTTNGSYSSVQCNGSV--CFCADYNGKAVA------GKPIVNIGQIQSLR 604
             +GA IP+CD  G + P+QC GS   C+CVD  G              RN    +       C+  R+  Q++     ++G     C   G Y   QC+GS   C+C D  G+  A      G P VN  Q   LR
Sbjct:   70 AVGAFIPQCDEEGQYRPLQCHGSTGHCWCVDNRGQERAGTRTPPGSPPRNCDEPVR--PKTHCEQHRDSLQSENGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVHLR 203
[Close]
BLAST of Thyroglobulin vs. Ensembl Zebrafish
Match: nid2a (nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GENE-030827-2])

HSP 1 Score: 49.6766 bits (117), Expect = 1.618e-6
Identity = 38/115 (33.04%), Postives = 53/115 (46.09%), Query Frame = 2 
Query:  269 LLGAPIPKCDSNGDFLPVQCTGSK--CYCVD-----REGNNIRNYAAHINEFANMDCKCAREQN-DYFLTG-----LIGKMF-SCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            ++GA IP+CD  G + P QC GS   C+CVD     R G      +  +N    +  K   EQ+ D   +G     ++G     C   G Y   QC+GS   C+C D  G+  AG
Sbjct: 1083 VVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDSRGQERAGTRTPPGSPRVNCDQPVRSKTHCEQHRDSLQSGDGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAG 1197

HSP 2 Score: 49.2914 bits (116), Expect = 2.374e-6
Identity = 38/124 (30.65%), Postives = 57/124 (45.97%), Query Frame = 2 
Query:  251 KARKGGL--LGAPIPKCDSNGDFLPVQCTGSK--CYCVD-----REGNNIRNYAAHIN--EFANMDCKCAREQNDYFLTG-----LIGKMF-SCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            ++  GG+  +GA IP+CD  G + P QC GS   C+CVD     R G      +  +N  +  ++  +C  +  D   +G      +G     C   G Y   QC+GS   C+C D  G+  AG
Sbjct:  923 QSENGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVHLRTRC-EQHRDSLQSGDGGVPAVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAG 1045
[Close]
BLAST of Thyroglobulin vs. Ensembl Zebrafish
Match: tg (thyroglobulin [Source:ZFIN;Acc:ZDB-GENE-030519-1])

HSP 1 Score: 48.9062 bits (115), Expect = 2.990e-6
Identity = 28/95 (29.47%), Postives = 43/95 (45.26%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS------CTTNGSYSSVQCNGSVCFCADYNG 550
            +P+C  +G +  VQC GS+C+CVD  G  +   +           +C +E+             S      C T+G+Y + QC G  CFC D +G
Sbjct:  606 LPQCTEDGLYQDVQCQGSECWCVDSRGLEVPG-SRTTGSRPRCPSQCEKERQMAIAVKASSSAGSEVFIPKCETDGAYVARQCLGKSCFCVDRSG 699
[Close]
BLAST of Thyroglobulin vs. Ensembl Zebrafish
Match: spock1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:ZFIN;Acc:ZDB-GENE-110428-1])

HSP 1 Score: 48.521 bits (114), Expect = 3.062e-6
Identity = 32/107 (29.91%), Postives = 57/107 (53.27%), Query Frame = 2 
Query:   80 IIMNKTILSLITIMNLLL-INKVYGTCQDSSD--CNNDLICIGNECSENPLNTQCFNKLNK----ARKGGLLGAPIPKCDSNGDFLPVQCTGS--KCYCVDREGNNI 373
            ++++++ LS I +    L +  ++ +C    D   +N+  C    C + P    C N++NK    +R+  LLG  +P+C  +G F   QC GS  +C+CVD+ GN +
Sbjct:  276 LLLDQSELSAIYLDKYELCMRPLFNSCDSFKDGKLSNNEWCY---CFQKPDGMPCQNEMNKIHSQSRRKTLLGVYVPRCTEDGYFKATQCHGSTGQCWCVDKYGNEL 379
[Close]
BLAST of Thyroglobulin vs. Ensembl Xenopus
Match: nid2 (nidogen 2 [Source:NCBI gene;Acc:100036716])

HSP 1 Score: 59.3066 bits (142), Expect = 1.312e-9
Identity = 52/188 (27.66%), Postives = 79/188 (42.02%), Query Frame = 2 
Query:  164 SSDCNNDLICIGNECSE----NPLNTQCFNKLNKARKGG---LLGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIR-----------NYAAHINEFANMDCKCAREQNDYFLTGLIGKMF-------------SCTTNGSYSSVQCNGSV--CFCADYNGKAVA------GKPIVNIGQIQSLR 604
            S  CN+     G +C++     PL T C  K  +    G    +G  +P+CD  G+++P+QC GS   C+CVD+ G  I            N      E     C   R+Q       L+G++               C   G+Y S+QC+GS   C+C D  G+ +A      G+P  N G+ +  R
Sbjct:  901 SCRCNSGYEGDGFQCTQILGPEPLKTPCLEKRQQLHPRGPRPAVGQFVPECDVEGNYVPLQCHGSTGHCWCVDKLGEEITGTRTPPGRPAPNCGETGPEPLKTPCLERRQQ-------LLGQLHPRGPRPAVGQFVPECDAEGNYVSLQCHGSTGHCWCVDKLGEEIAGTRTPPGRPGPNCGETEPTR 1081
[Close]
BLAST of Thyroglobulin vs. Ensembl Xenopus
Match: amd1 (adenosylmethionine decarboxylase 1 [Source:Xenbase;Acc:XB-GENE-484611])

HSP 1 Score: 58.5362 bits (140), Expect = 2.960e-9
Identity = 34/113 (30.09%), Postives = 53/113 (46.90%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNI---RNYAAHINEFANMDCKCAREQ------NDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQ 595
            IP C  +G +  +QC+ ++C+CVD +G  I   R    H         KC +E+       +    G    + +C   G + +VQC G +CFC D  G+ + G   V+ G IQ
Sbjct:  617 IPACKEDGRYNDIQCSKAECWCVDDQGREIDRTRTQGTH----PRCPTKCEKERYRQTAVRESLPPGAELFIPACDLEGHFLTVQCTGKLCFCVDLEGRIIPGTQKVSGGDIQ 725

HSP 2 Score: 50.8322 bits (120), Expect = 1.136e-6
Identity = 39/113 (34.51%), Postives = 50/113 (44.25%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQC-TGSKCYCVDREGNNIR-NYAAHINEFANM-DCKCAREQNDYFL----TGLIGKMFSCTTNGSYSSVQCNGSVC--FCADYNGKAVAGKPIVNIGQIQ 595
            +P CD NGDF P+QC TG +C+CVD +G  I       ++   NM DC   R Q    L    TG  GK     T       Q N   C  +  D  GK+    PI+   + Q
Sbjct:  323 VPSCDDNGDFNPIQCQTGQQCWCVDSKGREIHGTRRLGVSPSCNMDDCPTKRRQALSSLFHGPTGHFGKHSLFVTQEEELGSQINAKFCSSYLTDLFGKSGLLFPIIQKVRFQ 435
[Close]
BLAST of Thyroglobulin vs. Ensembl Xenopus
Match: nid2 (nidogen 2 [Source:NCBI gene;Acc:100036716])

HSP 1 Score: 56.6102 bits (135), Expect = 1.309e-8
Identity = 48/172 (27.91%), Postives = 75/172 (43.60%), Query Frame = 2 
Query:  164 SSDCNNDLICIGNECSE----NPLNTQCFNKLNKARKGG---LLGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIRNY-------AAHINEFANMDCK--CAREQNDYFLTG---LIGKMF-SCTTNGSYSSVQCNGSV--CFCADYNGKAVA------GKPIVNIGQ 589
            S  CN+     G +C++     PL T C  K  +    G    +G  +P+CD  G+++P+QC GS   C+CVD+ G  I          A +  E      K  C  ++      G    +G+    C   G+Y  +QC+GS   C+C D  G+ +       G+P  N G+
Sbjct:  901 SCRCNSGYEGDGFQCTQILGPEPLKTPCLEKRQQLHPRGPRPAVGQFVPECDVEGNYVPLQCHGSTGHCWCVDKLGEEITGTRTPPGRPAPNCGERGPEPLKTPCLEKRQQLHPRGPRPAVGQFVPECDVEGNYVPLQCHGSTGHCWCVDKLGEEITGTRTPPGRPAPNCGE 1072
[Close]
BLAST of Thyroglobulin vs. Ensembl Xenopus
Match: nid2 (nidogen 2 [Source:NCBI gene;Acc:100036716])

HSP 1 Score: 54.299 bits (129), Expect = 6.016e-8
Identity = 45/156 (28.85%), Postives = 71/156 (45.51%), Query Frame = 2 
Query:  164 SSDCNNDLICIGNECSENPLNTQCFNKLNKARKGG---LLGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIRNY-------AAHINEFANMDCK---CAREQN---DYFLTGLIGKMF--SCTTNGSYSSVQCNGS--VCFCADYNGKAVAG 565
            S  CN+     G +C E PL T C  K  +    G    +G  +P+CD  G+++P+QC GS   C+CVD+ G  I          A +  E      K   C R +    +++     G+ +   C   G +S +QC+G+   C+C D  G+ + G
Sbjct:  872 SCRCNSGYEGDGFQCPE-PLKTPCLEKRQQLHPRGPRPAVGQFVPECDVEGNYVPLQCHGSTGHCWCVDKLGEEITGTRTPPGRPAPNCGERGPEPLKTPLCERWKQSLIEHYGGKPGGEHYVPQCDQYGDFSPLQCHGNSGYCWCVDKEGREIEG 1026
[Close]
BLAST of Thyroglobulin vs. Ensembl Xenopus
Match: nid2 (nidogen 2 [Source:NCBI gene;Acc:100036716])

HSP 1 Score: 52.7582 bits (125), Expect = 1.986e-7
Identity = 44/160 (27.50%), Postives = 72/160 (45.00%), Query Frame = 2 
Query:  164 SSDCNNDLICIGNECSE----NPLNTQCFNKLNKARKGG---LLGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIRNY-------AAHINEFANMDCK---CAREQN---DYFLTGLIGKMF--SCTTNGSYSSVQCNGS--VCFCADYNGKAVAG 565
            S  CN+     G +C++     PL T C  K  +    G    +G  +P+CD  G+++P+QC GS   C+CVD+ G  I          A +  E      K   C R +    +++     G+ +   C   G +S +QC+G+   C+C D  G+ + G
Sbjct:  859 SCRCNSGYEGDGFQCTQILGPEPLKTPCLEKRQQLHPRGPRPAVGQFVPECDVEGNYVPLQCHGSTGHCWCVDKLGEEITGTRTPPGRPAPNCGERGPEPLKTPLCERWKQSLIEHYGGKPGGEHYVPQCDQYGDFSPLQCHGNSGYCWCVDKEGREIEG 1018
[Close]
BLAST of Thyroglobulin vs. Ensembl Mouse
Match: Tg (thyroglobulin [Source:MGI Symbol;Acc:MGI:98733])

HSP 1 Score: 55.8398 bits (133), Expect = 1.790e-8
Identity = 31/94 (32.98%), Postives = 43/94 (45.74%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS---------------CTTNGSYSSVQCNG 520
            +P C   G FLPVQC  S+CYCVD EG  I    + + E       C  +    FL G++G + S               C+ +G +  VQC+G
Sbjct:  684 VPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQSTVGEAKQCPSVCQLQAEQAFL-GVVGVLLSNSSMVPSISNVYIPQCSASGQWRHVQCDG 776
[Close]
BLAST of Thyroglobulin vs. UniProt/SwissProt
Match: sp|P01267|THYG_BOVIN (Thyroglobulin OS=Bos taurus OX=9913 GN=TG PE=1 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 7.273e-9
Identity = 39/120 (32.50%), Postives = 55/120 (45.83%), Query Frame = 2 
Query:  227 TQCFNKLNKARKGGLLGAP-------IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS---------------CTTNGSYSSVQCNG 520
            T+C  +  +AR   LLG+        +P C S G+FLPVQC  S+CYCVD EG  I    + + E       C  +    FL G +  + S               C+ +G +S VQC+G
Sbjct:  659 TEC--EKQRARMQSLLGSQPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIPGTRSALGEPKKCPSPCQLQAERAFL-GTVRTLVSNPSTLPALSSIYIPQCSASGQWSPVQCDG 775

HSP 2 Score: 53.1434 bits (126), Expect = 1.076e-6
Identity = 30/102 (29.41%), Postives = 46/102 (45.10%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGK------MF--SCTTNGSYSSVQCNGSVCFCADYNGKAVAG 565
            +P C + G +  VQC    C+CVD +G   R  A          C    E+    +  L+G       +F  +CT+ G++  VQC  S C+C D  G+ + G
Sbjct:  616 VPACTAEGSYEEVQCFAGDCWCVDAQG---RELAGSRVRGGRPRCPTECEKQRARMQSLLGSQPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIPG 714
[Close]
BLAST of Thyroglobulin vs. UniProt/SwissProt
Match: sp|P01266|THYG_HUMAN (Thyroglobulin OS=Homo sapiens OX=9606 GN=TG PE=1 SV=5)

HSP 1 Score: 57.7658 bits (138), Expect = 2.490e-8
Identity = 35/111 (31.53%), Postives = 49/111 (44.14%), Query Frame = 2 
Query:  251 KARKGGLLGAP-------IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS--------------CTTNGSYSSVQCNG 520
            +AR   L+G+        +P C S G FLPVQC  S+CYCVD EG  I    + I +       C  +    FL  +   + +              C+T+G +  VQCNG
Sbjct:  666 RARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAIGKPKKCPTPCQLQSEQAFLRTVQALLSNSSMLPTLSDTYIPQCSTDGQWRQVQCNG 776
[Close]
BLAST of Thyroglobulin vs. UniProt/SwissProt
Match: sp|P06882|THYG_RAT (Thyroglobulin OS=Rattus norvegicus OX=10116 GN=Tg PE=1 SV=4)

HSP 1 Score: 57.7658 bits (138), Expect = 2.731e-8
Identity = 34/94 (36.17%), Postives = 45/94 (47.87%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS---------------CTTNGSYSSVQCNG 520
            +P C S G FLPVQC  S+CYCVD EG  I    + I E       C  +    FL G++G + S               C+T+G +  VQC+G
Sbjct:  684 VPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQSTIGEPKLCPSVCQLQAEQAFL-GVVGVLLSNSSMVPPISSVYIPQCSTSGQWMPVQCDG 776
[Close]
BLAST of Thyroglobulin vs. UniProt/SwissProt
Match: sp|F1RRV3|THYG_PIG (Thyroglobulin OS=Sus scrofa OX=9823 GN=TG PE=1 SV=5)

HSP 1 Score: 56.225 bits (134), Expect = 9.308e-8
Identity = 31/102 (30.39%), Postives = 46/102 (45.10%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGK--------MFSCTTNGSYSSVQCNGSVCFCADYNGKAVAG 565
            +P C + G +  VQC   +C+CVD  G   R  A          C  A E+    +  L+G+        + SCT  G +  VQC  S C+C D +G+ + G
Sbjct:  618 VPSCTAEGSYEDVQCFAGECWCVDARG---RELAGSRARGGRPRCPTACEKQRERMQSLLGRQPAGSSVFVPSCTREGHFLPVQCFSSDCYCVDADGQPIPG 716

HSP 2 Score: 50.447 bits (119), Expect = 6.464e-6
Identity = 30/93 (32.26%), Postives = 38/93 (40.86%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFL---TGLIGK-----------MFSCTTNGSYSSVQCNG 520
            +P C   G FLPVQC  S CYCVD +G  I        E       C  +    FL    GLI             +  C+ +G +  VQC+G
Sbjct:  685 VPSCTREGHFLPVQCFSSDCYCVDADGQPIPGTRTAPGEPKQCPTPCQLQAEQAFLGTVRGLISNPSEPPVLSSIYIPQCSASGQWRRVQCDG 777
[Close]
BLAST of Thyroglobulin vs. UniProt/SwissProt
Match: sp|O08710|THYG_MOUSE (Thyroglobulin OS=Mus musculus OX=10090 GN=Tg PE=1 SV=3)

HSP 1 Score: 55.8398 bits (133), Expect = 1.252e-7
Identity = 31/94 (32.98%), Postives = 43/94 (45.74%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS---------------CTTNGSYSSVQCNG 520
            +P C   G FLPVQC  S+CYCVD EG  I    + + E       C  +    FL G++G + S               C+ +G +  VQC+G
Sbjct:  684 VPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQSTVGEAKQCPSVCQLQAEQAFL-GVVGVLLSNSSMVPSISNVYIPQCSASGQWRHVQCDG 776
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BLAST of Thyroglobulin vs. TrEMBL
Match: A0A194AKI3 (Uncharacterized protein OS=Pinctada fucata OX=50426 PE=4 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 1.568e-33
Identity = 63/130 (48.46%), Postives = 80/130 (61.54%), Query Frame = 2 
Query:  224 NTQCFNKLNKARKG-GLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN 610
            +  C   L KA+ G  LLGAP P CD  G + P QC GS+CYCV + G  I  Y A++ E   M C+CAR+Q +Y  +GLIGK F CT++GSY + QC G VCFCAD NG  +   P V+I Q+  L C 
Sbjct:  108 DAPCAAALLKAQNGPSLLGAPTPSCDGEGYYQPKQCQGSQCYCVSKNGKEISGYTANVWEAQQMTCQCARDQAEYMASGLIGKFFYCTSDGSYQTYQCQGDVCFCADTNGVKMDHSPSVHISQVTKLNCK 237
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BLAST of Thyroglobulin vs. TrEMBL
Match: A0A1S3J5E7 (equistatin-like OS=Lingula unguis OX=7574 GN=LOC106170269 PE=4 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 3.156e-27
Identity = 49/126 (38.89%), Postives = 79/126 (62.70%), Query Frame = 2 
Query:  236 FNKLNKARKGG--LLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRC 607
              ++ ++R+ G  LLGA  P CD++G +   QC  + C+CV+++G+ + +Y+A   E  +M C CAR++++Y   GLIGKM+ C  NG+Y   QC GSVC+C D  G  +   P V+I  +++L C
Sbjct:    7 LARIEESRRQGQPLLGATPPTCDADGTYSAKQCKEASCFCVNKDGDRLGDYSARFWEAKDMTCNCARDEDEYQKKGLIGKMYICKENGNYEKYQCTGSVCYCVDEKGSKLESTPPVSISAVKTLNC 132
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BLAST of Thyroglobulin vs. TrEMBL
Match: A0A210PVS8 (Testican-3 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT04456 PE=4 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 2.685e-26
Identity = 58/114 (50.88%), Postives = 73/114 (64.04%), Query Frame = 2 
Query:  266 GLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRC 607
            GLLGA  P CD NG + P QC GS C CV + G +I NY A I +  +M+C+CAR+Q +Y  TGLIG+ F CT NG+Y + QC GSVC C D  G+ V G   V+IG +  L C
Sbjct:  125 GLLGAVEPLCDENGFYQPKQCEGSVCSCVSKTGRDILNYRADIWQSEDMNCQCARDQQEYMDTGLIGRFFYCTPNGNYQNHQCLGSVCHCIDNRGQMV-GTQTVSIGDLAKLSC 237
[Close]
BLAST of Thyroglobulin vs. TrEMBL
Match: A0A1S3IF36 (uncharacterized protein LOC106163748 OS=Lingula unguis OX=7574 GN=LOC106163748 PE=4 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 8.477e-26
Identity = 49/126 (38.89%), Postives = 79/126 (62.70%), Query Frame = 2 
Query:  236 FNKLNKARKGG--LLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRC 607
              ++ ++R+ G  LLGA  P CD++G +   QC  + C+CV+++G+ + +Y+A   E  +M C CAR++++Y   GLIGKM+ C  NG+Y   QC GSVC+C D  G  +   P V+I  +++L C
Sbjct:  105 LARIEESRRQGQPLLGATPPTCDADGTYSAKQCIEASCFCVNKDGDRLGDYSARFWEAKDMTCNCARDEDEYQKKGLIGKMYICNENGNYEKYQCTGSVCYCVDEKGSKLESTPPVSISAVKTLNC 230
[Close]
BLAST of Thyroglobulin vs. TrEMBL
Match: V4AXA0 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_238761 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 1.659e-25
Identity = 60/122 (49.18%), Postives = 78/122 (63.93%), Query Frame = 2 
Query:  245 LNKARKGG-LLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRC 607
            L++ + GG LLGA  PKCDS+G +  VQC GS+C+C    G N+  Y  +      MDCKCAR+Q+ Y  TGLIGK+F C  NG+Y + QC GSVC+C D NGK V     +NIG + +L C
Sbjct:  112 LDQKQNGGILLGAEEPKCDSDGTYSAVQCIGSQCHCTSAGGKNL-GYPVNRGLTQGMDCKCARDQDTYAKTGLIGKLFYCGPNGNYRNYQCVGSVCWCKDSNGKQVGQS--INIGLLSTLHC 230
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BLAST of Thyroglobulin vs. Ensembl Cavefish
Match: tg (thyroglobulin [Source:NCBI gene;Acc:103037495])

HSP 1 Score: 51.9878 bits (123), Expect = 2.233e-7
Identity = 29/97 (29.90%), Postives = 48/97 (49.48%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCT-GSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            IP+C  +G +  VQC  G +C+CV+ +G  I   +   +        C  ++    L+G  G +  C  +G Y  VQC+G++  C+C D  G  + G
Sbjct:   80 IPQCSEDGRYRYVQCNRGGECWCVNSDGTEIPG-SRQNDTVVTCLTPCQLQRQRLLLSGDAGVVPRCLDSGEYEPVQCDGALGQCWCVDMEGMEIYG 175

HSP 2 Score: 51.9878 bits (123), Expect = 2.538e-7
Identity = 32/114 (28.07%), Postives = 49/114 (42.98%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFS------CTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRC 607
            +P+C  +G +  VQC GS+C+C D +G  +   +  I        +C +E+             S      C  +G Y S+QC G  CFC D  G   +      +G   SL+C
Sbjct:  626 LPQCTEDGQYQAVQCQGSECWCADSQGQEVMG-SRSIGYRPRCPSRCEKERMMAIAVKASSSAGSEVFIPKCEEDGEYVSLQCLGKSCFCLDQRGVRYS-----TLGSGSSLQC 733
[Close]
BLAST of Thyroglobulin vs. Ensembl Cavefish
Match: spock1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:ZFIN;Acc:ZDB-GENE-110428-1])

HSP 1 Score: 49.6766 bits (117), Expect = 1.073e-6
Identity = 33/107 (30.84%), Postives = 57/107 (53.27%), Query Frame = 2 
Query:   80 IIMNKTILSLITIMNLLL-INKVYGTCQDSSD--CNNDLICIGNECSENPLNTQCFNKLNK----ARKGGLLGAPIPKCDSNGDFLPVQCTGS--KCYCVDREGNNI 373
            ++++++ LS I +    L +  ++ +C    D   +N+  C    C + P    C N++N+     R+  L+GA IP+C  +G F   QC GS  +C+CVD+ GN I
Sbjct:  177 LLLDQSELSAIYLDKYELCMRPLFNSCDSFKDGKLSNNEWCY---CFQKPEGLPCQNEMNRIHGQGRRKALIGAYIPRCTEDGYFKATQCHGSTGQCWCVDKYGNEI 280
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BLAST of Thyroglobulin vs. Ensembl Cavefish
Match: nid2b (nidogen 2b (osteonidogen) [Source:ZFIN;Acc:ZDB-GENE-040724-143])

HSP 1 Score: 49.2914 bits (116), Expect = 1.898e-6
Identity = 38/114 (33.33%), Postives = 49/114 (42.98%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTGSK--CYCVD-----REGNNIRNYAAHIN-----EFANMDCKCAREQNDYFLTGLIGK------MFSCTTNGSYSSVQCNG--SVCFCADYNGKAVAG 565
            IP+CD  G + P+QC GS   C+CVD     R G       AH N          +  C R +    L+   G+      M  C   G + SVQC G  S C+C D  G+ V G
Sbjct:  721 IPQCDEKGQYKPLQCLGSTGHCWCVDSRGQERVGTRTLPGTAHANCDQPPLVPRAETLCERWRTT-LLSHYGGQPDPQDYMPQCDARGHFLSVQCYGNSSYCWCVDSQGREVMG 833
[Close]
BLAST of Thyroglobulin vs. Ensembl Cavefish
Match: nid2a (nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GENE-030827-2])

HSP 1 Score: 48.521 bits (114), Expect = 3.654e-6
Identity = 43/138 (31.16%), Postives = 57/138 (41.30%), Query Frame = 2 
Query:  212 ENPLNTQCFNKLNKARKGG-----LLGAPIPKCDSNGDFLPVQCTGSK--CYCVD-----REGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGK------MFSCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            E P  TQC    +  ++G      L GA +P+CD  G + P QC GS   C+CVD     R+G      +   N  A    K   EQ+   L    G       +  C   G Y   QC+GS   C+C D  G+   G
Sbjct:  768 ERP-KTQCEQHRDSLQRGSDDGLTLEGAFVPECDEQGQYRPQQCHGSTGHCWCVDSRGQERQGTRTPPGSPQFNCDAPERPKTQCEQHRDSLQRGDGSPPVGAYVPQCDDQGQYRPQQCHGSTGHCWCVDSRGQERQG 904

HSP 2 Score: 47.7506 bits (112), Expect = 5.306e-6
Identity = 39/137 (28.47%), Postives = 55/137 (40.15%), Query Frame = 2 
Query:  203 ECSENPLNTQCFNKLNKARKGG---LLGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGL--------IGKMF-SCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            +  E P  TQC    +  ++G     +GA +P+CD  G + P QC GS   C+CVD  G   R            +C   + Q +     L        +G     C   G Y   QC+GS   C+C D  G+   G
Sbjct:  842 DAPERP-KTQCEQHRDSLQRGDGSPPVGAYVPQCDDQGQYRPQQCHGSTGHCWCVDSRGQE-RQGTRTPPGSPRFNCDRPKTQCEQHRDSLQRGDGSPPVGAFVPECDEQGQYRPQQCHGSTGHCWCVDIRGQERQG 976
[Close]
BLAST of Thyroglobulin vs. Ensembl Sea Lamprey
Match: tg (thyroglobulin [Source:ZFIN;Acc:ZDB-GENE-030519-1])

HSP 1 Score: 48.9062 bits (115), Expect = 5.754e-7
Identity = 29/108 (26.85%), Postives = 45/108 (41.67%), Query Frame = 2 
Query:  254 ARKGGLLGAP--IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGL--IGKMF--------------SCTTNGSYSSVQCNGS 523
            AR+G  +G P  +P+CD  GD+ PVQC+G +C+CV   G  +      + +       C        L  L  +G +                C   G +  VQC+G+
Sbjct:  664 ARRGRPVGTPLFVPECDGAGDYRPVQCSGDRCFCVGAGGAEVPGTGRPLGDPVTCPTPCQAAAASELLQQLRHLGPVLRGDAPSSLPPLYVPRCDARGGWRPVQCDGA 771

HSP 2 Score: 47.7506 bits (112), Expect = 1.235e-6
Identity = 31/101 (30.69%), Postives = 40/101 (39.60%), Query Frame = 2 
Query:  284 IPKC-DSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFL------TGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAG 565
            + +C +  G + PVQC G+ C+CVD  G  I    A           C  E+    L       G    +  C   G Y  VQC+G  CFC    G  V G
Sbjct:  607 VARCGEDGGAYEPVQCHGAACWCVDAHGREIAGTRAVGGAPPRCPSACEGERARALLARRGRPVGTPLFVPECDGAGDYRPVQCSGDRCFCVGAGGAEVPG 707
[Close]
BLAST of Thyroglobulin vs. Ensembl Nematostella
Match: EDO40370 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7C1])

HSP 1 Score: 55.0694 bits (131), Expect = 1.815e-9
Identity = 38/123 (30.89%), Postives = 57/123 (46.34%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQC-TGSK-CYCVDREGNNIRNYAAHI----NEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSV--CFCADYNGKAVAGKPIVNIGQIQSLRCN*DNISA 628
            IP C S+G +  VQC TG+K C+CVD +G  +             F      C R + +  L+    ++ +C  +GSYS VQC+ S   C+C+  +G    G          +LRC  +  SA
Sbjct:   23 IPHCKSDGRYEEVQCHTGTKYCWCVDEKGVEVWGTRTRTFIRCAAFVKEPTPCQRAKGEALLSPETKRVPNCRPDGSYSRVQCDKSTGECWCSSEDGSETPGTRTSG-----TLRCPANEFSA 140
[Close]
BLAST of Thyroglobulin vs. Ensembl Nematostella
Match: EDO40372 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7C3])

HSP 1 Score: 53.5286 bits (127), Expect = 7.114e-9
Identity = 33/108 (30.56%), Postives = 50/108 (46.30%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQC--TGSKCYCVDREGNNIRNYAAH-INEFANMDCKCAREQNDYFLTGLIGKMFS------CTTNGSYSSVQCNG--SVCFCADYNGKAVAGKPI 574
            +P+CD++G + PVQC  T   C+CVD++G  IR      +            E+  Y   G  G   +      C  +GSY SVQC+     C+C D +G  + G  +
Sbjct:   75 VPRCDASGGYEPVQCLSTTGHCWCVDKDGIEIRGTRRRGVRPVCKQGYNTPCERERYRALGWTGLRVTGLWVPDCRPDGSYESVQCHALSGYCWCVDRSGHELFGTRV 182
[Close]
BLAST of Thyroglobulin vs. Ensembl Nematostella
Match: EDO38469 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCV6])

HSP 1 Score: 52.7582 bits (125), Expect = 1.362e-8
Identity = 41/136 (30.15%), Postives = 59/136 (43.38%), Query Frame = 2 
Query:  224 NTQCFNKLNKARKGGLLGAP---IPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDC------KCAREQNDYFLTGLIGKMF-SCTTNGSYSSVQCNGSVCFC-------ADYNGKAVAGKPIVN 580
             T C ++L  A     + +P   +P C S G F  VQC GS  YC     +N +       +    DC      KC R   D  +   IG+   +C  +G+Y  +QC+GS  FC       A+  G  + GKP+ N
Sbjct:   54 KTVCQSQLEAALGPDGIASPGRFVPLCTSEGKFADVQCHGSTGYCWCAHPDNGQEVTG-TRQRGQPDCSDVALSKCQRHYRDNLIYPPIGRFLPTCKPDGNYEKMQCHGSTGFCWCVDADGAELVGSRLRGKPLCN 188
[Close]
BLAST of Thyroglobulin vs. Ensembl Nematostella
Match: EDO40373 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7C4])

HSP 1 Score: 51.6026 bits (122), Expect = 2.857e-8
Identity = 35/108 (32.41%), Postives = 55/108 (50.93%), Query Frame = 2 
Query:  275 GAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIRNYAAHINEFANMDC---KCAREQNDYFLTGLIGK------MFSCTTNGSYSSVQCNGSV--CFCADYNGKAV 559
            G+ +PKC S+GD+  VQC GS   C+CVD +GN I            +     +C +E+  +   G++G       + +CT+ G Y  VQC+ S   C+C D  G+ +
Sbjct:   75 GSFVPKCKSSGDYDTVQCHGSTGFCWCVDDDGNEIPATRVRGRPMCGLLAGLSQCQQERQRHM--GVLGIAPPGRFVPACTSTGQYERVQCHSSTGYCWCVDKFGREL 180
[Close]
BLAST of Thyroglobulin vs. Ensembl Nematostella
Match: EDO47797 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL43])

HSP 1 Score: 48.9062 bits (115), Expect = 2.997e-7
Identity = 40/142 (28.17%), Postives = 64/142 (45.07%), Query Frame = 2 
Query:  203 ECSENPLNTQCFNKLNKARKGGLLGAP-----IPKCDSNGDFLPVQC-TGSK-CYCVDREGNNI---------RNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSV--CFCADYNGKAVAGKPI 574
            +C +    T C  +   A   GL G P     +P+C   G +  VQC TG+  C+CVD  G  I         R + A  +E  N   + A  ++   L+G    +  C  +G ++ +QC+ +   C+C D NG  +AG  +
Sbjct:   44 DCKKAAQTTSCQRQRTAAL--GLTGRPNSARYLPQCKPTGRYEEVQCHTGTGLCWCVDERGQEITRTRTWGYPRCHMAPKSECYNRRREAAHARSARRLSGFPFFVSQCQPDGGFTPLQCHSATGFCWCVDGNGNELAGTRV 183

HSP 2 Score: 44.669 bits (104), Expect = 7.664e-6
Identity = 33/109 (30.28%), Postives = 46/109 (42.20%), Query Frame = 2 
Query:  284 IPKCDSNGDFLPVQCTG--SKCYCVDREGNNIRNYAAHINEFANMDCK-------CAREQNDYFLTGLIGK------MFSCTTNGSYSSVQCN--GSVCFCADYNGKAV 559
            IP C  +G F  VQC G   +C+CVD  G  I      +      DCK       C R++      GL G+      +  C   G Y  VQC+    +C+C D  G+ +
Sbjct:    2 IPTCRDDGSFAEVQCHGLTGQCWCVDMNGIEI---PGSVTRGHRPDCKKAAQTTSCQRQRTAAL--GLTGRPNSARYLPQCKPTGRYEEVQCHTGTGLCWCVDERGQEI 105
[Close]
BLAST of Thyroglobulin vs. Ensembl Medaka
Match: nid2a (nidogen 2 [Source:NCBI gene;Acc:101173773])

HSP 1 Score: 51.2174 bits (121), Expect = 4.907e-7
Identity = 35/116 (30.17%), Postives = 53/116 (45.69%), Query Frame = 2 
Query:  272 LGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIRNYAAHINEFANMDCK--------CAREQNDYFLTGLIGKMFS------CTTNGSYSSVQCNGS--VCFCADYNGKAVAG 565
            +GA +P+CD NG+++P QC  S   C+CVD  G   R+         +MDC         C R +     +   G+  +      C  +G Y   QC+GS   C+C D +G+   G
Sbjct:  861 VGAYVPQCDQNGEYVPQQCHTSTGYCWCVDGMGQE-RSGTRSAPGSPSMDCSKPGAPKTPCERLRESVLASSAGGRPLAGAYAPQCDEDGHYVPRQCHGSSGYCWCVDSSGQERPG 975

HSP 2 Score: 48.1358 bits (113), Expect = 4.673e-6
Identity = 37/116 (31.90%), Postives = 52/116 (44.83%), Query Frame = 2 
Query:  269 LLGAPIPKCDSNGDFLPVQCTGSK--CYCVD-----REGNNIRNYAAHIN----EFANMDCKCAREQ---NDYFLTGLIGKMF-SCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            L GA  P+CD +G ++P QC GS   C+CVD     R G      A  ++    E    +C+  RE+   +        G+    C   G Y S QC+GS   C+C D  G+   G
Sbjct:  937 LAGAYAPQCDEDGHYVPRQCHGSSGYCWCVDSSGQERPGTRTSPGAPSVDCKEPEAPKTECELLRERAMASSPEAVPAAGRFVPQCDAEGRYLSQQCHGSTGHCWCVDSRGQERPG 1052

HSP 3 Score: 47.3654 bits (111), Expect = 7.231e-6
Identity = 35/116 (30.17%), Postives = 52/116 (44.83%), Query Frame = 2 
Query:  269 LLGAPIPKCDSNGDFLPVQCTGSK--CYCVD-----REGNNIRNYAAHI--NEFANMDCKCAREQNDYFLT------GLIGKMFSCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            LLG  +P+CD +G +LP QC  S   C+CVD     R G      +A +  NE  +   +C R +     +       +   +  C  NG Y   QC+ S   C+C D  G+  +G
Sbjct:  783 LLGVYVPQCDESGKYLPQQCHDSTGYCWCVDSTGQERTGTRTPPGSALVDCNEQPHYKTRCERHREHVLASEREDRPSVGAYVPQCDQNGEYVPQQCHTSTGYCWCVDGMGQERSG 898
[Close]
BLAST of Thyroglobulin vs. Ensembl Medaka
Match: nid2a (nidogen 2 [Source:NCBI gene;Acc:101173773])

HSP 1 Score: 50.8322 bits (120), Expect = 6.024e-7
Identity = 35/119 (29.41%), Postives = 53/119 (44.54%), Query Frame = 2 
Query:  272 LGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGNNIRNYAAHINEFANMDCK-----------CAREQNDYFLTGLIGKMFS------CTTNGSYSSVQCNGS--VCFCADYNGKAVAG 565
            +GA +P+CD NG+++P QC  S   C+CVD  G   R+         +MDC            C R +     +   G+  +      C  +G Y   QC+GS   C+C D +G+   G
Sbjct:  940 VGAYVPQCDQNGEYVPQQCHTSTGYCWCVDGMGQE-RSGTRSAPGSPSMDCSKPDEALQPKTPCERLRESVLASSAGGRPLAGAYAPQCDEDGHYVPRQCHGSSGYCWCVDSSGQERPG 1057

HSP 2 Score: 48.1358 bits (113), Expect = 4.649e-6
Identity = 36/119 (30.25%), Postives = 51/119 (42.86%), Query Frame = 2 
Query:  269 LLGAPIPKCDSNGDFLPVQCTGSK--CYCVDREGN------------NIRNYAAHINEFANMDCKCAREQ---NDYFLTGLIGKMF-SCTTNGSYSSVQCNGSV--CFCADYNGKAVAG 565
            L GA  P+CD +G ++P QC GS   C+CVD  G             ++    A   E    +C+  RE+   +        G+    C   G Y S QC+GS   C+C D  G+   G
Sbjct: 1019 LAGAYAPQCDEDGHYVPRQCHGSSGYCWCVDSSGQERPGTRTSPGAPSVDCSRAEEPEAPKTECELLRERAMASSPEAVPAAGRFVPQCDAEGRYLSQQCHGSTGHCWCVDSRGQERPG 1137
[Close]
BLAST of Thyroglobulin vs. Planmine SMEST
Match: SMESG000016977.1 (SMESG000016977.1)

HSP 1 Score: 351.288 bits (900), Expect = 9.594e-125
Identity = 173/175 (98.86%), Postives = 175/175 (100.00%), Query Frame = 2 
Query:   86 MNKTILSLITIMNLLLINKVYGTCQDSSDCNNDLICIGNECSENPLNTQCFNKLNKARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN 610
            MNKTILSLITIMNLLLINKVYGTCQDSSDCNNDLICIGNECS+NPLNTQCFNKL+KARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN
Sbjct:    1 MNKTILSLITIMNLLLINKVYGTCQDSSDCNNDLICIGNECSDNPLNTQCFNKLSKARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN 175
[Close]
BLAST of Thyroglobulin vs. Planmine SMEST
Match: SMESG000016977.1 (SMESG000016977.1)

HSP 1 Score: 330.102 bits (845), Expect = 1.881e-116
Identity = 162/164 (98.78%), Postives = 164/164 (100.00%), Query Frame = 2 
Query:  119 MNLLLINKVYGTCQDSSDCNNDLICIGNECSENPLNTQCFNKLNKARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN 610
            MNLLLINKVYGTCQDSSDCNNDLICIGNECS+NPLNTQCFNKL+KARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN
Sbjct:    1 MNLLLINKVYGTCQDSSDCNNDLICIGNECSDNPLNTQCFNKLSKARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN 164
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BLAST of Thyroglobulin vs. Planmine SMEST
Match: SMESG000016994.1 (SMESG000016994.1)

HSP 1 Score: 131.339 bits (329), Expect = 5.172e-38
Identity = 70/176 (39.77%), Postives = 100/176 (56.82%), Query Frame = 2 
Query:   98 ILSLITIMNLLLINKVYGTCQDSSD-CNNDLICIGNE-CSENPLNTQCFNKLNKARK---GGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN 610
            ++SL        + + +  C +  D CN  L C  NE C E+     CF K    R+     ++G  +P C+ NGD+ PVQC GS C+CVD+ G  I  +++ I +  N  CKCA+++++Y    LIG+ F C   G+Y   QC+GSVCFCAD NGK  +G P VNIGQ+  L+C 
Sbjct:    6 VISLFASCVFCEVLEEFQLCLNEEDKCNYGLFC--NEICEEDEEAPDCFKKHLDVRRKLANKVIGIRLPNCEENGDYKPVQCLGSVCHCVDKHGERIEGFSSPIYKSTNKTCKCAKDRDEYQKLRLIGRYFGCDNQGNYKRTQCHGSVCFCADENGKKTSGSPTVNIGQLDQLKCE 179
[Close]
BLAST of Thyroglobulin vs. Planmine SMEST
Match: SMESG000017161.1 (SMESG000017161.1)

HSP 1 Score: 121.324 bits (303), Expect = 2.426e-34
Identity = 68/168 (40.48%), Postives = 98/168 (58.33%), Query Frame = 2 
Query:  104 SLITIMNLLLINKVYGTCQDSSDCNNDLICIGNECSENPLNTQCFNKLNKARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRC 607
            S+I  + L LI+  +G C DS  C +  +C+   CS+NPL T+C+ + +K  K  L G+ IP C +NG + PVQC  + CYC   +G  I NY  +INE  N +CKC  ++  Y L   +G +F+C  NGSY  +QC GS C+C D  GK + G   V+I +   L+C
Sbjct:    3 SVIGCVFLALIHAAFG-CNDSKGCTDLEVCVSGNCSKNPLTTKCYQEYDKVMKNLLFGSFIPCCKTNGIYCPVQCPTNICYCSSPDGKKISNY-FNINE--NSNCKCGLDKYLYSLNMAVGIIFNCNENGSYRPIQCLGSSCYCVDAQGKKIPGTISVHIEKANELKC 166
[Close]
BLAST of Thyroglobulin vs. Planmine SMEST
Match: SMESG000016992.1 (SMESG000016992.1)

HSP 1 Score: 117.087 bits (292), Expect = 1.887e-32
Identity = 60/149 (40.27%), Postives = 85/149 (57.05%), Query Frame = 2 
Query:  173 CNNDLICIGNECSENPLNTQCFNK---LNKARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYAAHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFCADYNGKAVAGKPIVNIGQIQSLRCN 610
            CN  L C    C E+     CF +   + +  K  +LGA  P C+ NGD+  +QC GS CYC D+ G  I  +   I+  AN +CKCA+E+++Y    LIG+ F C+  G+Y   QC+GSVC+CAD +GK V G   V+I     L+C+
Sbjct:   32 CNYGLSC-DKVCKEDTEAPDCFKQHLAVRRRWKEHILGARAPSCEENGDYKALQCVGSVCYCSDKNGVEISGFITPIHLSANKNCKCAKERDEYHKKHLIGRFFRCSELGNYEKAQCHGSVCYCADEDGKKVEGSQTVHIVDFDKLKCD 179
The following BLAST results are available for this feature:
BLAST of Thyroglobulin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TG5.185e-931.53thyroglobulin [Source:HGNC Symbol;Acc:HGNC:11764][more]
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BLAST of Thyroglobulin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroglobulin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroglobulin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nid2a1.695e-733.04nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GEN... [more]
nid2a1.010e-630.88nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GEN... [more]
nid2a1.618e-633.04nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GEN... [more]
tg2.990e-629.47thyroglobulin [Source:ZFIN;Acc:ZDB-GENE-030519-1][more]
spock13.062e-629.91SPARC (osteonectin), cwcv and kazal like domains p... [more]
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BLAST of Thyroglobulin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nid21.312e-927.66nidogen 2 [Source:NCBI gene;Acc:100036716][more]
amd12.960e-930.09adenosylmethionine decarboxylase 1 [Source:Xenbase... [more]
nid21.309e-827.91nidogen 2 [Source:NCBI gene;Acc:100036716][more]
nid26.016e-828.85nidogen 2 [Source:NCBI gene;Acc:100036716][more]
nid21.986e-727.50nidogen 2 [Source:NCBI gene;Acc:100036716][more]
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BLAST of Thyroglobulin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Tg1.790e-832.98thyroglobulin [Source:MGI Symbol;Acc:MGI:98733][more]
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BLAST of Thyroglobulin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P01267|THYG_BOVIN7.273e-932.50Thyroglobulin OS=Bos taurus OX=9913 GN=TG PE=1 SV=... [more]
sp|P01266|THYG_HUMAN2.490e-831.53Thyroglobulin OS=Homo sapiens OX=9606 GN=TG PE=1 S... [more]
sp|P06882|THYG_RAT2.731e-836.17Thyroglobulin OS=Rattus norvegicus OX=10116 GN=Tg ... [more]
sp|F1RRV3|THYG_PIG9.308e-830.39Thyroglobulin OS=Sus scrofa OX=9823 GN=TG PE=1 SV=... [more]
sp|O08710|THYG_MOUSE1.252e-732.98Thyroglobulin OS=Mus musculus OX=10090 GN=Tg PE=1 ... [more]
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BLAST of Thyroglobulin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A194AKI31.568e-3348.46Uncharacterized protein OS=Pinctada fucata OX=5042... [more]
A0A1S3J5E73.156e-2738.89equistatin-like OS=Lingula unguis OX=7574 GN=LOC10... [more]
A0A210PVS82.685e-2650.88Testican-3 OS=Mizuhopecten yessoensis OX=6573 GN=K... [more]
A0A1S3IF368.477e-2638.89uncharacterized protein LOC106163748 OS=Lingula un... [more]
V4AXA01.659e-2549.18Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
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BLAST of Thyroglobulin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
tg2.233e-729.90thyroglobulin [Source:NCBI gene;Acc:103037495][more]
spock11.073e-630.84SPARC (osteonectin), cwcv and kazal like domains p... [more]
nid2b1.898e-633.33nidogen 2b (osteonidogen) [Source:ZFIN;Acc:ZDB-GEN... [more]
nid2a3.654e-631.16nidogen 2a (osteonidogen) [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Thyroglobulin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tg5.754e-726.85thyroglobulin [Source:ZFIN;Acc:ZDB-GENE-030519-1][more]
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BLAST of Thyroglobulin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroglobulin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO403701.815e-930.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO403727.114e-930.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO384691.362e-830.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO403732.857e-832.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO477972.997e-728.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Thyroglobulin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nid2a4.907e-730.17nidogen 2 [Source:NCBI gene;Acc:101173773][more]
nid2a6.024e-729.41nidogen 2 [Source:NCBI gene;Acc:101173773][more]
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BLAST of Thyroglobulin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000016977.19.594e-12598.86SMESG000016977.1[more]
SMESG000016977.11.881e-11698.78SMESG000016977.1[more]
SMESG000016994.15.172e-3839.77SMESG000016994.1[more]
SMESG000017161.12.426e-3440.48SMESG000017161.1[more]
SMESG000016992.11.887e-3240.27SMESG000016992.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016345 ID=SMED30016345|Name=Thyroglobulin|organism=Schmidtea mediterranea sexual|type=transcript|length=729bp
CTTATTTAATTTATCAGTTTGGCAATAATTTAACAGAATTTATTAATTGC
AATTATTTCTTTACTATTTATCTATAATAATAATAATGAACAAAACCATA
TTGAGTTTAATCACAATTATGAATTTGTTGTTAATTAACAAAGTTTATGG
TACATGTCAGGATTCTTCTGATTGTAATAATGACTTAATATGCATTGGAA
ATGAATGCTCCGAAAATCCATTAAACACTCAATGTTTTAATAAATTGAAT
AAAGCTCGAAAAGGTGGGCTTTTAGGTGCACCAATTCCCAAATGTGATTC
CAATGGTGATTTTCTACCCGTTCAGTGTACCGGTTCTAAATGCTATTGTG
TTGACAGGGAAGGAAATAATATACGAAATTATGCAGCTCACATTAATGAA
TTTGCAAATATGGATTGCAAATGCGCCAGAGAACAAAATGATTATTTTTT
GACTGGATTGATCGGGAAAATGTTCTCTTGCACCACCAATGGAAGCTATA
GTTCAGTTCAGTGCAACGGATCGGTTTGTTTCTGTGCTGATTATAATGGC
AAGGCAGTTGCTGGCAAGCCCATTGTTAATATCGGTCAAATACAATCATT
GCGCTGTAATTAAGATAATATATCCGCGCACTTGATTTTGAACTTCTAAT
TAACATCTATTTACGTTTTCATTTGATTATTTATTTATTGCCATTTTTAA
TAAATCATTTTGTTTGGTCGAAAAAAAAA
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protein sequence of SMED30016345-orf-1

>SMED30016345-orf-1 ID=SMED30016345-orf-1|Name=SMED30016345-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=176bp
MNKTILSLITIMNLLLINKVYGTCQDSSDCNNDLICIGNECSENPLNTQC
FNKLNKARKGGLLGAPIPKCDSNGDFLPVQCTGSKCYCVDREGNNIRNYA
AHINEFANMDCKCAREQNDYFLTGLIGKMFSCTTNGSYSSVQCNGSVCFC
ADYNGKAVAGKPIVNIGQIQSLRCN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005615extracellular space
GO:0005576extracellular region
Vocabulary: biological process
TermDefinition
GO:0006590thyroid hormone generation
GO:0015705iodide transport
GO:0030878thyroid gland development
GO:0031641regulation of myelination
GO:0042403thyroid hormone metabolic process
GO:0042446hormone biosynthetic process
Vocabulary: molecular function
TermDefinition
GO:0042802identical protein binding
GO:0005179hormone activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR036857Thyroglobulin_1_sf
IPR000716Thyroglobulin_1
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000716Thyroglobulin type-1SMARTSM00211TY_2coord: 67..117
e-value: 1.0E-7
score: 41.6
coord: 129..170
e-value: 0.064
score: 15.2
IPR000716Thyroglobulin type-1PFAMPF00086Thyroglobulin_1coord: 64..99
e-value: 4.0E-10
score: 39.2
coord: 131..162
e-value: 3.9E-8
score: 32.9
IPR000716Thyroglobulin type-1PROSITEPS51162THYROGLOBULIN_1_2coord: 112..174
score: 6.768
IPR000716Thyroglobulin type-1PROSITEPS51162THYROGLOBULIN_1_2coord: 47..111
score: 8.879
IPR000716Thyroglobulin type-1CDDcd00191TYcoord: 54..96
e-value: 2.93042E-9
score: 48.9993
IPR036857Thyroglobulin type-1 superfamilyGENE3DG3DSA:4.10.800.10coord: 113..165
e-value: 5.2E-7
score: 30.9
coord: 47..112
e-value: 3.3E-12
score: 47.6
IPR036857Thyroglobulin type-1 superfamilySUPERFAMILYSSF57610Thyroglobulin type-1 domaincoord: 49..113
IPR036857Thyroglobulin type-1 superfamilySUPERFAMILYSSF57610Thyroglobulin type-1 domaincoord: 131..164
NoneNo IPR availablePANTHERPTHR12352SECRETED MODULAR CALCIUM-BINDING PROTEINcoord: 24..117
coord: 131..161
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..22
score: 0.797