Dmd-1 splice form 1

Overview


Name	Dmd-1 splice form 1 (AGL61623.1)
Smed ID	SMED30016325
Length (bp)	1012

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Dmd-1 splice form 1 (SMED30016325) t-SNE clustered cells

Violin plots show distribution of expression levels for Dmd-1 splice form 1 (SMED30016325) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dmd-1 splice form 1 (SMED30016325) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dmd-1 splice form 1 (SMED30016325) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016325

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 60

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30016325	SMESG000080385.1	SmedASXL_003739	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
X1 cell	SMED30016325	SMESG000080385.1	SmedASXL_003739	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30016325	SMESG000080385.1	SmedASXL_003739	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Smed sexual biotype	SMED30016325	SMESG000080385.1	Contig55528	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016325	SMESG000080385.1	Contig55528	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
penis papilla	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cholinergic neuron	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
sperm duct	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
seminal vesicle	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia neuron	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis somatic gonadal cell	SMED30016325	SMESG000080385.1	KC736557	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
penis papilla	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cholinergic neuron	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
sperm duct	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
seminal vesicle	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia neuron	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis somatic gonadal cell	SMED30016325	SMESG000080385.1	KC736558	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
penis papilla	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cholinergic neuron	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
sperm duct	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
seminal vesicle	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia neuron	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis somatic gonadal cell	SMED30016325	SMESG000080385.1	KC736555	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
penis papilla	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cholinergic neuron	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis primordium	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
sperm duct	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
seminal vesicle	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
cephalic ganglia neuron	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
testis somatic gonadal cell	SMED30016325	SMESG000080385.1	KC736556	smed_ncbi_20200123	PMID:23652002 Chong et al., 2013
neuron	SMED30016325	SMESG000080385.1	Contig55528	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
neuron	SMED30016325	SMESG000080385.1	Contig55528	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
penis papilla	SMED30016325	SMESG000080385.1	KC736555.1	smed_ncbi_20200123	PMID:27074666 Lander et al., 2016

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Human
Match: DMRTA1 (DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826])

HSP 1 Score: 53.1434 bits (126), Expect = 4.066e-7
Identity = 24/60 (40.00%), Postives = 36/60 (60.00%), Query Frame = 3

Query:  360 PQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKS 539
            P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +   + ++  +E+S
Sbjct:   92 PRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEES 151

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Human
Match: DMRTA2 (DMRT like family A2 [Source:HGNC Symbol;Acc:HGNC:13908])

HSP 1 Score: 53.1434 bits (126), Expect = 4.491e-7
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   61 AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 129

[Close]

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   61 AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 129

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Human
Match: DMRT1 (doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934])

HSP 1 Score: 52.373 bits (124), Expect = 5.542e-7
Identity = 24/46 (52.17%), Postives = 30/46 (65.22%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            SK+SP+ P C RCRNHG  +  KGHK+ C   +C CK C LI  R+
Sbjct:   67 SKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQ 112

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Human
Match: DMRT3 (doublesex and mab-3 related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:13909])

HSP 1 Score: 50.0618 bits (118), Expect = 3.147e-6
Identity = 20/41 (48.78%), Postives = 28/41 (68.29%), Query Frame = 3

Query:  363 QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            ++P C RCRNHG  +  KGHK+ CR  +C C+ C+LI  R+
Sbjct:   25 RTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQ 65

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Celegans
Match: mab-3 (Protein male abnormal 3 [Source:UniProtKB/Swiss-Prot;Acc:O18214])

HSP 1 Score: 58.151 bits (139), Expect = 1.784e-9
Identity = 32/98 (32.65%), Postives = 49/98 (50.00%), Query Frame = 3

Query:  207 HGQLLPVKNHRRNCPFKLCPCPLCTVVSHGRE----IVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKK-CRHSNCPCKLCLLITMRK 485
            HG+L P K H+ +C +  CPC  CT+V   R+    +  ++I      +    +  + PHC RC  HG     +GHK+  C+   C C LC L+  R+
Sbjct:   34 HGELKPRKGHKPDCRYLKCPCRECTMVEQRRQLNNLLSKKKIHCTPATQTRDGKRVRDPHCARCSAHGVLVPLRGHKRTMCQFVTCECTLCTLVEHRR 131

HSP 2 Score: 51.2174 bits (121), Expect = 3.207e-7
Identity = 23/47 (48.94%), Postives = 33/47 (70.21%), Query Frame = 3

Query:  204 AHGQLLPVKNHRRN-CPFKLCPCPLCTVVSHGREIVARQIRLYRNQK 341
            AHG L+P++ H+R  C F  C C LCT+V H R ++A QI+L R+Q+
Sbjct:   99 AHGVLVPLRGHKRTMCQFVTCECTLCTLVEHRRNLMAAQIKLRRSQQ 145

HSP 3 Score: 46.9802 bits (110), Expect = 8.327e-6
Identity = 18/38 (47.37%), Postives = 25/38 (65.79%), Query Frame = 3

Query:  372 HCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            +C+RC NHGE    KGHK  CR+  CPC+ C ++  R+
Sbjct:   27 YCQRCLNHGELKPRKGHKPDCRYLKCPCRECTMVEQRR 64

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Celegans
Match: dmd-5 (DM (Doublesex/MAB-3) Domain family [Source:UniProtKB/TrEMBL;Acc:Q19291])

HSP 1 Score: 51.6026 bits (122), Expect = 2.379e-7
Identity = 25/57 (43.86%), Postives = 33/57 (57.89%), Query Frame = 3

Query:  315 QIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            +IR  RNQ+        +P C RCRNHG  +A KGHK+ C+  +C C  C LI  R+
Sbjct:   21 RIRAERNQR--------TPKCARCRNHGTTSALKGHKRYCQWKDCMCAKCTLIAERQ 69

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Celegans
Match: dmd-8 (DM (Doublesex/MAB-3) Domain family [Source:UniProtKB/TrEMBL;Acc:Q9TXN8])

HSP 1 Score: 49.6766 bits (117), Expect = 1.463e-6
Identity = 34/123 (27.64%), Postives = 54/123 (43.90%), Query Frame = 3

Query:  207 HGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPH--------------------------CRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEK 497
            HG  +  + H   C ++ C C  C +V   REI++ QIRL R Q    +R+                               C++C+NH      K HKK+C++S+C C+ C LI  R+  ++
Sbjct:   57 HGVFVETRGH--TCEYRSCECEQCDLVRKRREIMSTQIRLRREQDKKFQRTNDISEANVFPGFTGGEADEKAVMENMNMCYFCQKCKNHNVLVWKKNHKKECQYSSCECQQCNLIDSRRALDR 177

[Close]

Query:  207 HGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPH--------------------------CRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEK 497
            HG  +  + H   C ++ C C  C +V   REI++ QIRL R Q    +R+                               C++C+NH      K HKK+C++S+C C+ C LI  R+  ++
Sbjct:   57 HGVFVETRGH--TCEYRSCECEQCDLVRKRREIMSTQIRLRREQDKKFQRTNDISEANVFPGFTGGEADEKAVMENMNMCYFCQKCKNHNVLVWKKNHKKECQYSSCECQQCNLIDSRRALDR 177

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Celegans
Match: dmd-10 (DM (Doublesex/MAB-3) Domain family [Source:UniProtKB/TrEMBL;Acc:G5EEJ1])

HSP 1 Score: 48.9062 bits (115), Expect = 2.076e-6
Identity = 20/45 (44.44%), Postives = 32/45 (71.11%), Query Frame = 3

Query:  207 HGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQK 341
            HG+   +K H+R+CPF+ CPC  C VVS  ++++A QI++ R Q+
Sbjct:   46 HGRKSRLKGHKRSCPFRECPCAKCAVVSERQKLMADQIKIRRRQR 90

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Fly
Match: dmrt99B (gene:FBgn0039683 transcript:FBtr0085454)

HSP 1 Score: 51.6026 bits (122), Expect = 5.406e-7
Identity = 27/72 (37.50%), Postives = 40/72 (55.56%), Query Frame = 3

Query:  339 KDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +  S+R  ++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   29 RAASERYQRTPKCARCRNHGVVSALKGHKRYCRWRDCVCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 100

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Fly
Match: dmrt93B (gene:FBgn0038851 transcript:FBtr0084007)

HSP 1 Score: 48.521 bits (114), Expect = 4.477e-6
Identity = 26/69 (37.68%), Postives = 35/69 (50.72%), Query Frame = 3

Query:  300 EIVARQIRLYRNQKDISKRSP-------QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            E+  ++ RL  N K      P       + P C RCRNHG  +  +GHKK C + NC C  C+LI  R+
Sbjct:   11 EVANKRPRLVANPKATKIVEPTPAKVTNRVPKCARCRNHGIISELRGHKKLCTYKNCKCAKCVLIFERQ 79

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Zebrafish
Match: dmrta2 (DMRT-like family A2 [Source:NCBI gene;Acc:474350])

HSP 1 Score: 53.1434 bits (126), Expect = 2.065e-7
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   50 TEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 118

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Zebrafish
Match: dmrt2b (doublesex and mab-3 related transcription factor 2b [Source:ZFIN;Acc:ZDB-GENE-080813-1])

HSP 1 Score: 51.2174 bits (121), Expect = 7.265e-7
Identity = 25/64 (39.06%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  294 GREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            GRE++        ++   ++R  +SP C RCRNHG  +  KGHK+ CR  +C C  CLL+  R+
Sbjct:   29 GREVMGT------DEAPAARRLSRSPKCARCRNHGVVSRLKGHKRLCRWRDCQCANCLLVVERQ 86

[Close]

Query:  294 GREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            GRE++        ++   ++R  +SP C RCRNHG  +  KGHK+ CR  +C C  CLL+  R+
Sbjct:   29 GREVMGT------DEAPAARRLSRSPKCARCRNHGVVSRLKGHKRLCRWRDCQCANCLLVVERQ 86

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Zebrafish
Match: dmrt2b (doublesex and mab-3 related transcription factor 2b [Source:ZFIN;Acc:ZDB-GENE-080813-1])

HSP 1 Score: 51.2174 bits (121), Expect = 7.397e-7
Identity = 25/64 (39.06%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  294 GREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            GRE++        ++   ++R  +SP C RCRNHG  +  KGHK+ CR  +C C  CLL+  R+
Sbjct:   29 GREVMGT------DEAPAARRLSRSPKCARCRNHGVVSRLKGHKRLCRWRDCQCANCLLVVERQ 86

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Zebrafish
Match: dmrt3a (doublesex and mab-3 related transcription factor 3a [Source:NCBI gene;Acc:450035])

HSP 1 Score: 50.8322 bits (120), Expect = 1.245e-6
Identity = 24/56 (42.86%), Postives = 33/56 (58.93%), Query Frame = 3

Query:  324 LYRNQKDISKRSP--QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            LY        R+P  ++P C RCRNHG  +  KGHK+ CR  +C C+ C+LI  R+
Sbjct:    9 LYMGGPVSQPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQ 64

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Xenopus
Match: dynll1 (dynein light chain LC8-type 1 [Source:Xenbase;Acc:XB-GENE-854521])

HSP 1 Score: 53.9138 bits (128), Expect = 1.760e-7
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   40 AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 108

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Xenopus
Match: dmrta1 (DMRT like family A1 [Source:NCBI gene;Acc:779901])

HSP 1 Score: 51.9878 bits (123), Expect = 8.389e-7
Identity = 22/42 (52.38%), Postives = 28/42 (66.67%), Query Frame = 3

Query:  360 PQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+
Sbjct:   78 PRTPKCARCRNHGVVSALKGHKRFCRWRDCSCAKCTLIAERQ 119

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Xenopus
Match: DMRT1 (doublesex and mab-3 related transcription factor 1 [Source:NCBI gene;Acc:100488257])

HSP 1 Score: 51.6026 bits (122), Expect = 9.183e-7
Identity = 23/45 (51.11%), Postives = 29/45 (64.44%), Query Frame = 3

Query:  351 KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            K+SP+ P C RCRNHG  +  KGHK+ C   +C CK C LI  R+
Sbjct:   24 KKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQ 68

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Xenopus
Match: st3gal4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:Xenbase;Acc:XB-GENE-963280])

HSP 1 Score: 51.2174 bits (121), Expect = 1.384e-6
Identity = 24/56 (42.86%), Postives = 33/56 (58.93%), Query Frame = 3

Query:  324 LYRNQKDISKRSP--QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            LY        R+P  ++P C RCRNHG  +  KGHK+ CR  +C C+ C+LI  R+
Sbjct:    9 LYMGGPVSQPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQ 64

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Mouse
Match: Dmrta1 (doublesex and mab-3 related transcription factor like family A1 [Source:MGI Symbol;Acc:MGI:2653627])

HSP 1 Score: 55.0694 bits (131), Expect = 6.591e-8
Identity = 31/89 (34.83%), Postives = 45/89 (50.56%), Query Frame = 3

Query:  273 LCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKS 539
            L +  S GR   A    L R    +    P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +   + ++  +E+S
Sbjct:   52 LRSTASSGRAGCAPGPGLDRALGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEES 140

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Mouse
Match: Dmrta2 (doublesex and mab-3 related transcription factor like family A2 [Source:MGI Symbol;Acc:MGI:2653629])

HSP 1 Score: 52.7582 bits (125), Expect = 3.583e-7
Identity = 26/68 (38.24%), Postives = 39/68 (57.35%), Query Frame = 3

Query:  351 KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            ++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   61 EKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 128

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Mouse
Match: Dmrt1 (doublesex and mab-3 related transcription factor 1 [Source:MGI Symbol;Acc:MGI:1354733])

HSP 1 Score: 51.9878 bits (123), Expect = 4.730e-7
Identity = 23/45 (51.11%), Postives = 29/45 (64.44%), Query Frame = 3

Query:  351 KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            K+SP+ P C RCRNHG  +  KGHK+ C   +C CK C LI  R+
Sbjct:   66 KKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQ 110

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Mouse
Match: Dmrt1 (doublesex and mab-3 related transcription factor 1 [Source:MGI Symbol;Acc:MGI:1354733])

HSP 1 Score: 50.447 bits (119), Expect = 9.483e-7
Identity = 24/66 (36.36%), Postives = 38/66 (57.58%), Query Frame = 3

Query:  351 KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILV 548
            K+SP+ P C RCRNHG  +  KGHK+ C   +C CK C LI  R+    +   + ++  +E+ + +
Sbjct:   66 KKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGI 131

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Mouse
Match: Dmrt3 (doublesex and mab-3 related transcription factor 3 [Source:MGI Symbol;Acc:MGI:2449470])

HSP 1 Score: 50.447 bits (119), Expect = 2.040e-6
Identity = 20/41 (48.78%), Postives = 28/41 (68.29%), Query Frame = 3

Query:  363 QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            ++P C RCRNHG  +  KGHK+ CR  +C C+ C+LI  R+
Sbjct:   25 RTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQ 65

[Close]

BLAST of Dmd-1 splice form 1 vs. UniProt/SwissProt
Match: sp|O18214|MAB3_CAEEL (Protein male abnormal 3 OS=Caenorhabditis elegans OX=6239 GN=mab-3 PE=1 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 2.269e-8
Identity = 32/98 (32.65%), Postives = 49/98 (50.00%), Query Frame = 3

Query:  207 HGQLLPVKNHRRNCPFKLCPCPLCTVVSHGRE----IVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKK-CRHSNCPCKLCLLITMRK 485
            HG+L P K H+ +C +  CPC  CT+V   R+    +  ++I      +    +  + PHC RC  HG     +GHK+  C+   C C LC L+  R+
Sbjct:   34 HGELKPRKGHKPDCRYLKCPCRECTMVEQRRQLNNLLSKKKIHCTPATQTRDGKRVRDPHCARCSAHGVLVPLRGHKRTMCQFVTCECTLCTLVEHRR 131

HSP 2 Score: 51.2174 bits (121), Expect = 4.079e-6
Identity = 23/47 (48.94%), Postives = 33/47 (70.21%), Query Frame = 3

Query:  204 AHGQLLPVKNHRRN-CPFKLCPCPLCTVVSHGREIVARQIRLYRNQK 341
            AHG L+P++ H+R  C F  C C LCT+V H R ++A QI+L R+Q+
Sbjct:   99 AHGVLVPLRGHKRTMCQFVTCECTLCTLVEHRRNLMAAQIKLRRSQQ 145

[Close]

BLAST of Dmd-1 splice form 1 vs. UniProt/SwissProt
Match: sp|Q8CFG4|DMRTA_MOUSE (Doublesex- and mab-3-related transcription factor A1 OS=Mus musculus OX=10090 GN=Dmrta1 PE=2 SV=1)

HSP 1 Score: 55.0694 bits (131), Expect = 4.610e-7
Identity = 31/89 (34.83%), Postives = 45/89 (50.56%), Query Frame = 3

Query:  273 LCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKS 539
            L +  S GR   A    L R    +    P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +   + ++  +E+S
Sbjct:   52 LRSTASSGRAGCAPGPGLDRALGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEES 140

[Close]

BLAST of Dmd-1 splice form 1 vs. UniProt/SwissProt
Match: sp|A4QNP7|DMTA2_XENTR (Doublesex- and mab-3-related transcription factor A2 OS=Xenopus tropicalis OX=8364 GN=dmrta2 PE=2 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 9.322e-7
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   40 AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 108

[Close]

BLAST of Dmd-1 splice form 1 vs. UniProt/SwissProt
Match: sp|Q2MJB4|DMTA2_XENLA (Doublesex- and mab-3-related transcription factor A2 OS=Xenopus laevis OX=8355 GN=dmrta2 PE=2 SV=1)

HSP 1 Score: 53.5286 bits (127), Expect = 1.155e-6
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   40 AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 108

[Close]

BLAST of Dmd-1 splice form 1 vs. UniProt/SwissProt
Match: sp|Q4AE28|DMTA2_TAKRU (Doublesex- and mab-3-related transcription factor A2 OS=Takifugu rubripes OX=31033 GN=dmrta2 PE=2 SV=1)

HSP 1 Score: 53.5286 bits (127), Expect = 1.156e-6
Identity = 23/46 (50.00%), Postives = 30/46 (65.22%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            S + P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+
Sbjct:   16 SDKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQ 61

[Close]

BLAST of Dmd-1 splice form 1 vs. TrEMBL
Match: R4PJJ9 (Dmd-1 splice form 1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 581.637 bits (1498), Expect = 0.000e+0
Identity = 323/324 (99.69%), Postives = 323/324 (99.69%), Query Frame = 3

Query:   15 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLXXXXXXXXXXXXXXXXXXXXXXAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVXXXXXXXXXXXXXXAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVFQHNSVEYLPTATPSWYSNFY 986
            MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNV QHNSVEYLPTATPSWYSNFY
Sbjct:    1 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVSQHNSVEYLPTATPSWYSNFY 324

[Close]

BLAST of Dmd-1 splice form 1 vs. TrEMBL
Match: R4PWS7 (Dmd-1 splice form 4 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 574.318 bits (1479), Expect = 0.000e+0
Identity = 324/341 (95.01%), Postives = 324/341 (95.01%), Query Frame = 3

Query:   15 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLXXXXXXXXXXXXXXXXXXXXXXAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVXXXXXXXXXXXXXXAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLY-----------------AQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVFQHNSVEYLPTATPSWYSNFY 986
            MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLY                 AQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVFQHNSVEYLPTATPSWYSNFY
Sbjct:    1 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYGYFQLIVWALVLIAFLLAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVFQHNSVEYLPTATPSWYSNFY 341

[Close]

BLAST of Dmd-1 splice form 1 vs. TrEMBL
Match: R4PLD6 (Dmd-1 splice form 2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 498.049 bits (1281), Expect = 7.127e-176
Identity = 283/283 (100.00%), Postives = 283/283 (100.00%), Query Frame = 3

Query:   15 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLXXXXXXXXXXXXXXXXXXXXXXAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVXXXXXXXXXXXXXXAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHN 863
            MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHN
Sbjct:    1 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHN 283

[Close]

BLAST of Dmd-1 splice form 1 vs. TrEMBL
Match: R4PU10 (Dmd-1 splice form 3 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 286.96 bits (733), Expect = 4.138e-94
Identity = 163/163 (100.00%), Postives = 163/163 (100.00%), Query Frame = 3

Query:   15 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLXXXXXXXXXXXXXXXXXXXXXXAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY 503
            MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY
Sbjct:    1 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY 163

[Close]

BLAST of Dmd-1 splice form 1 vs. TrEMBL
Match: A0A0R3U081 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS13504 PE=4 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 4.182e-32
Identity = 64/132 (48.48%), Postives = 86/132 (65.15%), Query Frame = 3

Query:  204 AHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQK----------------------DISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEE 533
            AHG+L+ V+ H+RNCP+K C C +C++V++GR IVARQI LYR+QK                      D      + PHCRRCRNHG+ N WKGHKK C    C C+ C+LIT+RK+NEK+ RE+VQE+++E
Sbjct:  106 AHGRLIAVRQHKRNCPYKHCSCSVCSLVNYGRHIVARQIALYRDQKNNHNDEGGNLGRGSRGDKTRGADKIDSEDEGPHCRRCRNHGKTNPWKGHKKVCPFYYCICQQCILITLRKSNEKNLREVVQESYKE 237

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Cavefish
Match: DMRTA1 (doublesex- and mab-3-related transcription factor A2 [Source:NCBI gene;Acc:103021351])

HSP 1 Score: 56.6102 bits (135), Expect = 1.338e-8
Identity = 26/79 (32.91%), Postives = 39/79 (49.37%), Query Frame = 3

Query:  312 RQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILV 548
            R   L R    + +  P++P C RCRNHG  +A KGHK+ CR   C C  C LI  R+    +   + ++  +E    +
Sbjct:   27 RAPLLLRAPAGLERAFPRTPKCARCRNHGVLSALKGHKRACRWRECACARCALIAERQRVMAAQVALRRQQEQESKTFI 105

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Cavefish
Match: DMRTA1 (doublesex- and mab-3-related transcription factor A2 [Source:NCBI gene;Acc:103021351])

HSP 1 Score: 55.8398 bits (133), Expect = 1.890e-8
Identity = 25/58 (43.10%), Postives = 32/58 (55.17%), Query Frame = 3

Query:  312 RQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            R   L R    + +  P++P C RCRNHG  +A KGHK+ CR   C C  C LI  R+
Sbjct:   13 RAPLLLRAPAGLERAFPRTPKCARCRNHGVLSALKGHKRACRWRECACARCALIAERQ 70

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Cavefish
Match: dmrta2 (DMRT like family A2 [Source:NCBI gene;Acc:103023395])

HSP 1 Score: 53.5286 bits (127), Expect = 1.392e-7
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  348 SKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            +++ P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   54 AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 122

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Cavefish
Match: dmrt3a (doublesex and mab-3 related transcription factor 3 [Source:NCBI gene;Acc:103040280])

HSP 1 Score: 50.0618 bits (118), Expect = 1.605e-6
Identity = 24/56 (42.86%), Postives = 32/56 (57.14%), Query Frame = 3

Query:  324 LYRNQKDISKRSP--QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            LY        R+P  ++P C RCRNHG  +  KGHK+ CR  +C C  C+LI  R+
Sbjct:    9 LYVGGPVAQARAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCDKCILIIERQ 64

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Cavefish
Match: dmrt1 (doublesex- and mab-3-related transcription factor 1 [Source:NCBI gene;Acc:103041212])

HSP 1 Score: 49.2914 bits (116), Expect = 2.005e-6
Identity = 21/45 (46.67%), Postives = 29/45 (64.44%), Query Frame = 3

Query:  351 KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            +R P+ P C RCRNHG  +  KGHK+ C   +C C+ C LI+ R+
Sbjct:   26 RRQPRMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCKLISERQ 70

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004009.1 (pep scaffold:Pmarinus_7.0:GL483432:15080:15595:1 gene:ENSPMAG00000003668.1 transcript:ENSPMAT00000004009.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 5.750e-8
Identity = 23/59 (38.98%), Postives = 35/59 (59.32%), Query Frame = 3

Query:  363 QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKS 539
            ++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +   + ++  +E+S
Sbjct:   50 RTPKCARCRNHGVVSALKGHKRYCRWRDCLCAKCTLIAERQRVMAAQVALRRQQAQEES 108

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Nematostella
Match: EDO45848 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL3])

HSP 1 Score: 46.2098 bits (108), Expect = 3.252e-7
Identity = 22/43 (51.16%), Postives = 28/43 (65.12%), Query Frame = 3

Query:  357 SPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            S ++P C RCRNHG  ++ KGHK  CR  +C C  CLLI  R+
Sbjct:    8 SQRTPKCARCRNHGVCSSLKGHKYYCRWRDCLCTKCLLIAERQ 50

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Nematostella
Match: EDO41281 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z8])

HSP 1 Score: 44.2838 bits (103), Expect = 1.265e-6
Identity = 20/39 (51.28%), Postives = 24/39 (61.54%), Query Frame = 3

Query:  369 PHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            P C RCRNHG  +  KGHK+ CR  +C C  C LI  R+
Sbjct:    2 PKCARCRNHGVVSWLKGHKRYCRWRDCNCAQCTLIAERQ 40

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Nematostella
Match: EDO37386 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFT8])

HSP 1 Score: 43.5134 bits (101), Expect = 2.630e-6
Identity = 21/39 (53.85%), Postives = 24/39 (61.54%), Query Frame = 3

Query:  369 PHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            P C RCRNHG  +  KGHK  CR  +C C  CLLI  R+
Sbjct:    3 PKCARCRNHGALSWLKGHKHYCRWRDCTCSKCLLIAERQ 41

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Nematostella
Match: EDO35744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKL0])

HSP 1 Score: 43.5134 bits (101), Expect = 2.931e-6
Identity = 20/39 (51.28%), Postives = 24/39 (61.54%), Query Frame = 3

Query:  369 PHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            P C RCR+HG  +  KGHK  CR  +C C  C LIT R+
Sbjct:    3 PKCARCRSHGTVSWLKGHKHYCRWRDCTCSKCQLITERQ 41

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Nematostella
Match: EDO36073 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJN2])

HSP 1 Score: 43.8986 bits (102), Expect = 3.437e-6
Identity = 20/41 (48.78%), Postives = 26/41 (63.41%), Query Frame = 3

Query:  363 QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            ++P C RCRNHG  +  KGHK  CR  +C C  C+LI  R+
Sbjct:   19 RTPKCARCRNHGFDSILKGHKGFCRWRDCMCPKCMLIAERQ 59

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Medaka
Match: dmrta2 (DMRT like family A2 [Source:NCBI gene;Acc:111947399])

HSP 1 Score: 53.1434 bits (126), Expect = 2.162e-7
Identity = 26/65 (40.00%), Postives = 37/65 (56.92%), Query Frame = 3

Query:  360 PQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   52 PRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 116

[Close]

Query:  360 PQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSY----REIVQETHEEKSI 542
            P++P C RCRNHG  +A KGHK+ CR  +C C  C LI  R+    +     R+  QE +E + +
Sbjct:   52 PRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEAREL 116

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Medaka
Match: dmy (Oryzias latipes doublesex- and mab-3-related transcription factor 1 (dmy), mRNA. [Source:RefSeq mRNA;Acc:NM_001104680])

HSP 1 Score: 51.9878 bits (123), Expect = 3.048e-7
Identity = 23/45 (51.11%), Postives = 29/45 (64.44%), Query Frame = 3

Query:  351 KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            +RSP+ P C RCRNHG  +  KGHK+ CR  +C C  C LI  R+
Sbjct:   19 QRSPRMPKCSRCRNHGFVSPLKGHKRFCRWKDCRCAKCKLIAERQ 63

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Medaka
Match: dmy (Oryzias latipes doublesex- and mab-3-related transcription factor 1 (dmy), mRNA. [Source:RefSeq mRNA;Acc:NM_001104680])

HSP 1 Score: 51.6026 bits (122), Expect = 3.214e-7
Identity = 24/50 (48.00%), Postives = 30/50 (60.00%), Query Frame = 3

Query:  336 QKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            +K    RSP+ P C RCRNHG  +  KGHK+ CR  +C C  C LI  R+
Sbjct:    4 EKQGRPRSPRMPKCSRCRNHGFVSPLKGHKRFCRWKDCRCAKCKLIAERQ 53

[Close]

BLAST of Dmd-1 splice form 1 vs. Ensembl Medaka
Match: dmy (Oryzias latipes doublesex- and mab-3-related transcription factor 1 (dmy), mRNA. [Source:RefSeq mRNA;Acc:NM_001104680])

HSP 1 Score: 51.6026 bits (122), Expect = 3.802e-7
Identity = 23/45 (51.11%), Postives = 29/45 (64.44%), Query Frame = 3

Query:  351 KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            +RSP+ P C RCRNHG  +  KGHK+ CR  +C C  C LI  R+
Sbjct:   19 QRSPRMPKCSRCRNHGFVSPLKGHKRFCRWKDCRCAKCKLIAERQ 63

[Close]

BLAST of Dmd-1 splice form 1 vs. Planmine SMEST
Match: SMESG000080385.1 (SMESG000080385.1)

HSP 1 Score: 585.104 bits (1507), Expect = 0.000e+0
Identity = 324/324 (100.00%), Postives = 324/324 (100.00%), Query Frame = 3

Query:   15 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLXXXXXXXXXXXXXXXXXXXXXXAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVXXXXXXXXXXXXXXAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVFQHNSVEYLPTATPSWYSNFY 986
            MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVFQHNSVEYLPTATPSWYSNFY
Sbjct:    1 MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSRKKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRSKDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNSENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGGHNVFQHNSVEYLPTATPSWYSNFY 324

[Close]

BLAST of Dmd-1 splice form 1 vs. Planmine SMEST
Match: SMESG000002896.1 (SMESG000002896.1)

HSP 1 Score: 98.2117 bits (243), Expect = 8.752e-23
Identity = 51/138 (36.96%), Postives = 68/138 (49.28%), Query Frame = 3

Query:  204 AHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVARQIRLYRNQKDIS-----------------------------------KRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREI 512
             HG+L+PVK H+R C +  C C  C +V  GR++VA+QI LYR+Q+ I                                    K +   PHCRRCRNH     WK HKK C + +CPC  C LI +RK  EK+ R++
Sbjct:   46 VHGKLVPVKRHKRTCLYLHCKCIKCLLVDQGRKVVAKQIALYRDQRHIGTEDRHSSETQDQRLVSFKEYRLRGTTASVKTNVSDKDAGMGPHCRRCRNHNVTVIWKNHKKSCPYRHCPCDPCRLINVRKDTEKTLRDM 183

[Close]

BLAST of Dmd-1 splice form 1 vs. Planmine SMEST
Match: SMESG000075920.1 (SMESG000075920.1)

HSP 1 Score: 47.7506 bits (112), Expect = 5.643e-6
Identity = 20/41 (48.78%), Postives = 26/41 (63.41%), Query Frame = 3

Query:  363 QSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRK 485
            ++P C RCRNHG  +  KGHK+ CR  +C C  C LI  R+
Sbjct:   50 RTPKCARCRNHGYVSPLKGHKRYCRWKDCVCAKCALIAERQ 90

[Close]

BLAST of Dmd-1 splice form 1 vs. Planmine SMEST
Match: SMESG000006521.1 (SMESG000006521.1)

HSP 1 Score: 47.7506 bits (112), Expect = 8.616e-6
Identity = 22/68 (32.35%), Postives = 37/68 (54.41%), Query Frame = 3

Query:  345 ISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLCLLITMRKTNEKSYREIVQETHEEKSILV 548
            I+++  + P C RCRNHG  +  KGHK+ C + +C C  C LI  R+    +   + ++   E +I +
Sbjct:   34 ITEKGARKPKCARCRNHGMVSWLKGHKRHCHYKDCRCAKCNLIAERQRVMAAQVALKRQQAAEDAIAI 101

The following BLAST results are available for this feature:

BLAST of Dmd-1 splice form 1 vs. Ensembl Human
BLAST of Dmd-1 splice form 1 vs. Ensembl Celegans
BLAST of Dmd-1 splice form 1 vs. Ensembl Fly
BLAST of Dmd-1 splice form 1 vs. Ensembl Zebrafish
BLAST of Dmd-1 splice form 1 vs. Ensembl Xenopus
BLAST of Dmd-1 splice form 1 vs. Ensembl Mouse
BLAST of Dmd-1 splice form 1 vs. UniProt/SwissProt
BLAST of Dmd-1 splice form 1 vs. TrEMBL
BLAST of Dmd-1 splice form 1 vs. Ensembl Cavefish
BLAST of Dmd-1 splice form 1 vs. Ensembl Sea Lamprey
BLAST of Dmd-1 splice form 1 vs. Ensembl Yeast
BLAST of Dmd-1 splice form 1 vs. Ensembl Nematostella
BLAST of Dmd-1 splice form 1 vs. Ensembl Medaka
BLAST of Dmd-1 splice form 1 vs. Planmine SMEST

BLAST of Dmd-1 splice form 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DMRTA1	4.066e-7	40.00	DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:1...	[more]
DMRTA2	4.491e-7	37.68	DMRT like family A2 [Source:HGNC Symbol;Acc:HGNC:1...	[more]
DMRTA2	4.491e-7	37.68	DMRT like family A2 [Source:HGNC Symbol;Acc:HGNC:1...	[more]
DMRT1	5.542e-7	52.17	doublesex and mab-3 related transcription factor 1...	[more]
DMRT3	3.147e-6	48.78	doublesex and mab-3 related transcription factor 3...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mab-3	1.784e-9	32.65	Protein male abnormal 3 [Source:UniProtKB/Swiss-P...	[more]
dmd-5	2.379e-7	43.86	DM (Doublesex/MAB-3) Domain family [Source:UniPro...	[more]
dmd-8	1.463e-6	27.64	DM (Doublesex/MAB-3) Domain family [Source:UniPro...	[more]
dmd-8	1.463e-6	27.64	DM (Doublesex/MAB-3) Domain family [Source:UniPro...	[more]
dmd-10	2.076e-6	44.44	DM (Doublesex/MAB-3) Domain family [Source:UniPro...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
dmrt99B	5.406e-7	37.50	gene:FBgn0039683 transcript:FBtr0085454	[more]
dmrt93B	4.477e-6	37.68	gene:FBgn0038851 transcript:FBtr0084007	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dmrta2	2.065e-7	37.68	DMRT-like family A2 [Source:NCBI gene;Acc:474350]	[more]
dmrt2b	7.265e-7	39.06	doublesex and mab-3 related transcription factor 2...	[more]
dmrt2b	7.265e-7	39.06	doublesex and mab-3 related transcription factor 2...	[more]
dmrt2b	7.397e-7	39.06	doublesex and mab-3 related transcription factor 2...	[more]
dmrt3a	1.245e-6	42.86	doublesex and mab-3 related transcription factor 3...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
dynll1	1.760e-7	37.68	dynein light chain LC8-type 1 [Source:Xenbase;Acc:...	[more]
dmrta1	8.389e-7	52.38	DMRT like family A1 [Source:NCBI gene;Acc:779901]	[more]
DMRT1	9.183e-7	51.11	doublesex and mab-3 related transcription factor 1...	[more]
st3gal4	1.384e-6	42.86	ST3 beta-galactoside alpha-2,3-sialyltransferase 4...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dmrta1	6.591e-8	34.83	doublesex and mab-3 related transcription factor l...	[more]
Dmrta2	3.583e-7	38.24	doublesex and mab-3 related transcription factor l...	[more]
Dmrt1	4.730e-7	51.11	doublesex and mab-3 related transcription factor 1...	[more]
Dmrt1	9.483e-7	36.36	doublesex and mab-3 related transcription factor 1...	[more]
Dmrt3	2.040e-6	48.78	doublesex and mab-3 related transcription factor 3...	[more]

BLAST of Dmd-1 splice form 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O18214\|MAB3_CAEEL	2.269e-8	32.65	Protein male abnormal 3 OS=Caenorhabditis elegans ...	[more]
sp\|Q8CFG4\|DMRTA_MOUSE	4.610e-7	34.83	Doublesex- and mab-3-related transcription factor ...	[more]
sp\|A4QNP7\|DMTA2_XENTR	9.322e-7	37.68	Doublesex- and mab-3-related transcription factor ...	[more]
sp\|Q2MJB4\|DMTA2_XENLA	1.155e-6	37.68	Doublesex- and mab-3-related transcription factor ...	[more]
sp\|Q4AE28\|DMTA2_TAKRU	1.156e-6	50.00	Doublesex- and mab-3-related transcription factor ...	[more]

BLAST of Dmd-1 splice form 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
R4PJJ9	0.000e+0	99.69	Dmd-1 splice form 1 OS=Schmidtea mediterranea OX=7...	[more]
R4PWS7	0.000e+0	95.01	Dmd-1 splice form 4 OS=Schmidtea mediterranea OX=7...	[more]
R4PLD6	7.127e-176	100.00	Dmd-1 splice form 2 OS=Schmidtea mediterranea OX=7...	[more]
R4PU10	4.138e-94	100.00	Dmd-1 splice form 3 OS=Schmidtea mediterranea OX=7...	[more]
A0A0R3U081	4.182e-32	48.48	Uncharacterized protein OS=Rodentolepis nana OX=10...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DMRTA1	1.338e-8	32.91	doublesex- and mab-3-related transcription factor ...	[more]
DMRTA1	1.890e-8	43.10	doublesex- and mab-3-related transcription factor ...	[more]
dmrta2	1.392e-7	37.68	DMRT like family A2 [Source:NCBI gene;Acc:10302339...	[more]
dmrt3a	1.605e-6	42.86	doublesex and mab-3 related transcription factor 3...	[more]
dmrt1	2.005e-6	46.67	doublesex- and mab-3-related transcription factor ...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000004009.1	5.750e-8	38.98	pep scaffold:Pmarinus_7.0:GL483432:15080:15595:1 g...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dmd-1 splice form 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO45848	3.252e-7	51.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41281	1.265e-6	51.28	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37386	2.630e-6	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35744	2.931e-6	51.28	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36073	3.437e-6	48.78	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Dmd-1 splice form 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dmrta2	2.162e-7	40.00	DMRT like family A2 [Source:NCBI gene;Acc:11194739...	[more]
dmrta2	2.162e-7	40.00	DMRT like family A2 [Source:NCBI gene;Acc:11194739...	[more]
dmy	3.048e-7	51.11	Oryzias latipes doublesex- and mab-3-related trans...	[more]
dmy	3.214e-7	48.00	Oryzias latipes doublesex- and mab-3-related trans...	[more]
dmy	3.802e-7	51.11	Oryzias latipes doublesex- and mab-3-related trans...	[more]

BLAST of Dmd-1 splice form 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4


Match Name	E-value	Identity	Description
SMESG000080385.1	0.000e+0	100.00	SMESG000080385.1	[more]
SMESG000002896.1	8.752e-23	36.96	SMESG000002896.1	[more]
SMESG000075920.1	5.643e-6	48.78	SMESG000075920.1	[more]
SMESG000006521.1	8.616e-6	32.35	SMESG000006521.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30016325
GenBank	AGL61623.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016325 ID=SMED30016325|Name=Dmd-1 splice form 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1012bp
TGTAGCATTAGAACATGAATTTAACTCAATGCCATTCGAAAATTAACGAT
TCTACCGGAAATTATTTGGAATTCAACCATTGCATTGTTGAAGATGATAA
AAGTGAAAATAATGAAGACGTCAAACCGAATTTACTGAAAAAAGAATATT
CTAGCAAATCGAGGAAAAAATCTCGTTCCTCATACATGTGTAGAAAATGT
CGAGCCCATGGCCAGTTGTTGCCGGTGAAAAACCATCGTCGAAATTGTCC
GTTTAAATTGTGTCCCTGTCCATTGTGTACAGTCGTTAGTCATGGTCGAG
AAATTGTCGCTCGTCAAATTAGACTTTATAGAAATCAGAAAGACATCAGC
AAAAGGTCTCCGCAATCACCACATTGTAGACGATGCAGAAATCATGGAGA
ACACAATGCTTGGAAAGGCCACAAAAAGAAATGTCGACATTCAAATTGTC
CCTGTAAATTGTGCCTGTTAATTACCATGAGAAAAACCAATGAAAAAAGT
TACAGAGAAATAGTTCAAGAAACTCACGAAGAGAAATCAATTTTAGTAAA
CAGCAACAATAATAGCAATAATAATAATAACAATAGTTCCGCATTCTGTC
TGTCAAACCGATCAAAAGACAGATCACTGGCAGAAGATCAGTCAGTTTTT
CTACGTAACATCAACCGAACTCCAATATTGCCAACGACAGGTTCGAATAT
CTACGACACCAGTCACAGCAGTTCGCTTTACGCTCAAAACTCAATGCTAA
ACTTTTCGAATTCCGAAAACTGCAACATTCGGCCCTTGAATTGGTCAACA
GCATCAGCCTATAAAGTTGGTTTACAGCCGTGGGACACTAACGGATCGTT
TGATATTCATAACAACGCCTCATATTGCGGCAGCTCACACCTGAACAACA
TGATGATTGGAGGTCATAACGTTTTCCAGCACAATTCCGTGGAATATCTA
CCAACGGCGACTCCATCTTGGTATTCAAATTTTTATTGAGATTGACTGGA
AATCTAACACGG

protein sequence of SMED30016325-orf-1

>SMED30016325-orf-1 ID=SMED30016325-orf-1|Name=SMED30016325-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=325bp
MNLTQCHSKINDSTGNYLEFNHCIVEDDKSENNEDVKPNLLKKEYSSKSR
KKSRSSYMCRKCRAHGQLLPVKNHRRNCPFKLCPCPLCTVVSHGREIVAR
QIRLYRNQKDISKRSPQSPHCRRCRNHGEHNAWKGHKKKCRHSNCPCKLC
LLITMRKTNEKSYREIVQETHEEKSILVNSNNNSNNNNNNSSAFCLSNRS
KDRSLAEDQSVFLRNINRTPILPTTGSNIYDTSHSSSLYAQNSMLNFSNS
ENCNIRPLNWSTASAYKVGLQPWDTNGSFDIHNNASYCGSSHLNNMMIGG
HNVFQHNSVEYLPTATPSWYSNFY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000044	cephalic ganglia
PLANA:0000099	neuron
PLANA:0000206	penis papilla
PLANA:0000207	sperm duct
PLANA:0000208	testis
PLANA:0000234	seminal vesicle
PLANA:0000419	prepharyngeal region
PLANA:0000463	cholinergic neuron
PLANA:0002016	cephalic ganglia neuron
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0003304	testis primordium
PLANA:0004506	testis somatic gonadal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036407	DM_DNA-bd_sf
IPR026607	DMRT/dsx/mab-3
IPR001275	DM_DNA-bd

Vocabulary: **molecular function**
Term	Definition
GO:0043565	sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001275	DM DNA-binding domain	SMART	SM00301	DM_3	coord: 55..108 e-value: 2.4E-12 score: 57.0 coord: 117..166 e-value: 2.7E-5 score: 33.6
IPR001275	DM DNA-binding domain	PFAM	PF00751	DM	coord: 118..158 e-value: 3.0E-12 score: 46.2 coord: 56..101 e-value: 3.5E-14 score: 52.4
IPR001275	DM DNA-binding domain	PROSITE	PS40000	DM_1	coord: 59..88
IPR001275	DM DNA-binding domain	PROSITE	PS40000	DM_1	coord: 121..150
IPR001275	DM DNA-binding domain	PROSITE	PS50809	DM_2	coord: 121..165 score: 10.483
IPR001275	DM DNA-binding domain	PROSITE	PS50809	DM_2	coord: 59..106 score: 11.278
IPR036407	DM DNA-binding domain superfamily	GENE3D	G3DSA:4.10.1040.10		coord: 111..161 e-value: 3.3E-14 score: 54.3 coord: 51..101 e-value: 1.4E-13 score: 52.3
IPR036407	DM DNA-binding domain superfamily	SUPERFAMILY	SSF82927	Cysteine-rich DNA binding domain, (DM domain)	coord: 116..158
IPR036407	DM DNA-binding domain superfamily	SUPERFAMILY	SSF82927	Cysteine-rich DNA binding domain, (DM domain)	coord: 54..99
IPR026607	DMRT/protein doublesex/protein male abnormal 3	PANTHER	PTHR12322	DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT	coord: 45..110 coord: 111..217

Main menu

Dmd-1 splice form 1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 60

Owlery

blazegraph-runner