Discoidin domain-containing receptor 2

Overview
NameDiscoidin domain-containing receptor 2
Smed IDSMED30016315
Length (bp)2488
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Discoidin domain-containing receptor 2 (SMED30016315) t-SNE clustered cells

Violin plots show distribution of expression levels for Discoidin domain-containing receptor 2 (SMED30016315) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Discoidin domain-containing receptor 2 (SMED30016315) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Discoidin domain-containing receptor 2 (SMED30016315) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30016315

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30016315h1SMcG0008178 Contig2554GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30016315h1SMcG0008178 dd_Smed_v4_6853_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30016315h1SMcG0008178 dd_Smed_v4_6853_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
enteric muscle cellSMED30016315h1SMcG0008178 dd_Smed_v4_6853_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Human
Match: DDR1 (discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730])

HSP 1 Score: 144.821 bits (364), Expect = 4.631e-35
Identity = 98/328 (29.88%), Postives = 160/328 (48.78%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN-------DQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    + LS    AVY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +  N   +  +  D ++  +   +  ++ ++LQ +  F   W+L SEI FIS+ 
Sbjct:   65 ESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMGWK----DRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMYLS---EAVY--LNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWP--GYDYVGWSNHSFSSG---YVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPAMAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDV 368          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Human
Match: DDR1 (discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730])

HSP 1 Score: 144.821 bits (364), Expect = 4.631e-35
Identity = 98/328 (29.88%), Postives = 160/328 (48.78%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN-------DQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    + LS    AVY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +  N   +  +  D ++  +   +  ++ ++LQ +  F   W+L SEI FIS+ 
Sbjct:   65 ESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMGWK----DRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMYLS---EAVY--LNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWP--GYDYVGWSNHSFSSG---YVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPAMAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDV 368          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Human
Match: DDR1 (discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730])

HSP 1 Score: 144.821 bits (364), Expect = 4.631e-35
Identity = 98/328 (29.88%), Postives = 160/328 (48.78%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN-------DQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    + LS    AVY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +  N   +  +  D ++  +   +  ++ ++LQ +  F   W+L SEI FIS+ 
Sbjct:   65 ESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMGWK----DRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMYLS---EAVY--LNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWP--GYDYVGWSNHSFSSG---YVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPAMAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDV 368          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Human
Match: DDR1 (discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730])

HSP 1 Score: 144.821 bits (364), Expect = 4.631e-35
Identity = 98/328 (29.88%), Postives = 160/328 (48.78%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN-------DQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    + LS    AVY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +  N   +  +  D ++  +   +  ++ ++LQ +  F   W+L SEI FIS+ 
Sbjct:   65 ESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMGWK----DRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMYLS---EAVY--LNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWP--GYDYVGWSNHSFSSG---YVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPAMAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDV 368          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Human
Match: DDR1 (discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730])

HSP 1 Score: 144.821 bits (364), Expect = 5.060e-35
Identity = 98/328 (29.88%), Postives = 160/328 (48.78%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN-------DQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    + LS    AVY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +  N   +  +  D ++  +   +  ++ ++LQ +  F   W+L SEI FIS+ 
Sbjct:   65 ESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMGWK----DRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMYLS---EAVY--LNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWP--GYDYVGWSNHSFSSG---YVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPAMAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDV 368          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Celegans
Match: ddr-2 (Discoidin domain-containing receptor tyrosine kinase B [Source:UniProtKB/Swiss-Prot;Acc:Q95ZV7])

HSP 1 Score: 120.168 bits (300), Expect = 1.323e-27
Identity = 114/392 (29.08%), Postives = 182/392 (46.43%), Query Frame = 1
Query:  109 ILVLFSIYFKQIYSKIDSRSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGT-NDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAK--FSLYGDKFSQKNTIIA-ENPELMSDSFSDSKSP-WIYFNMQEKIGQYLQLKLYF--KSEWILLSEIDFIS 1263
            +L LF + F           +C  +L      + D   +ASS F         +    P+ AR    +++   AWCP+N++    +++L+I     TVI   +T+GRF  G G E++  +KIQY R   + W  YK  D  L   E +   ND        LD  I+ R +RI P S     VC+++++FGC F+D ++ Y + +G +        SGI       + D S+DG   +   L  G+G+L D + G N     +    +VGW R   G     +V L F F  +RN S   + I  ++  K S      A   FS+ G  FS  +TI+   NPE      ++S+ P WI   +  +I +  +++L F   S+W+ +SE++F S
Sbjct:    4 LLYLFGVTFHSNTVVALELRECSHQLGMSNRKIRDEQISASSSF--------DLQSTGPQHARA--HQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKD-DFEL---ETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDLQ-------SGIS------YHDFSYDGNLANSPHLTGGIGKLYDGEVGKNNVFVNHHK--WVGWRRKRNG-----NVKLAFEFSELRNISG--ILIHTSNEFKKSAKAFSSATVLFSINGKDFS--DTIVHFNNPE-----DTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFES 352          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Celegans
Match: ddr-2 (Discoidin domain-containing receptor tyrosine kinase B [Source:UniProtKB/Swiss-Prot;Acc:Q95ZV7])

HSP 1 Score: 118.242 bits (295), Expect = 5.118e-27
Identity = 108/360 (30.00%), Postives = 172/360 (47.78%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGT-NDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAK--FSLYGDKFSQKNTIIA-ENPELMSDSFSDSKSP-WIYFNMQEKIGQYLQLKLYF--KSEWILLSEIDFIS 1263
            + D   +ASS F         +    P+ AR    +++   AWCP+N++    +++L+I     TVI   +T+GRF  G G E++  +KIQY R   + W  YK  D  L   E +   ND        LD  I+ R +RI P S     VC+++++FGC F+D ++ Y + +G +        SGI       + D S+DG   +   L  G+G+L D + G N     +    +VGW R   G     +V L F F  +RN S   + I  ++  K S      A   FS+ G  FS  +TI+   NPE      ++S+ P WI   +  +I +  +++L F   S+W+ +SE++F S
Sbjct:    6 IRDEQISASSSF--------DLQSTGPQHARA--HQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKD-DFEL---ETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDLQ-------SGIS------YHDFSYDGNLANSPHLTGGIGKLYDGEVGKNNVFVNHHK--WVGWRRKRNG-----NVKLAFEFSELRNISG--ILIHTSNEFKKSAKAFSSATVLFSINGKDFS--DTIVHFNNPE-----DTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFES 322          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Celegans
Match: ddr-2 (Discoidin domain-containing receptor tyrosine kinase B [Source:UniProtKB/Swiss-Prot;Acc:Q95ZV7])

HSP 1 Score: 118.242 bits (295), Expect = 5.118e-27
Identity = 108/360 (30.00%), Postives = 172/360 (47.78%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGT-NDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAK--FSLYGDKFSQKNTIIA-ENPELMSDSFSDSKSP-WIYFNMQEKIGQYLQLKLYF--KSEWILLSEIDFIS 1263
            + D   +ASS F         +    P+ AR    +++   AWCP+N++    +++L+I     TVI   +T+GRF  G G E++  +KIQY R   + W  YK  D  L   E +   ND        LD  I+ R +RI P S     VC+++++FGC F+D ++ Y + +G +        SGI       + D S+DG   +   L  G+G+L D + G N     +    +VGW R   G     +V L F F  +RN S   + I  ++  K S      A   FS+ G  FS  +TI+   NPE      ++S+ P WI   +  +I +  +++L F   S+W+ +SE++F S
Sbjct:    6 IRDEQISASSSF--------DLQSTGPQHARA--HQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKD-DFEL---ETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDLQ-------SGIS------YHDFSYDGNLANSPHLTGGIGKLYDGEVGKNNVFVNHHK--WVGWRRKRNG-----NVKLAFEFSELRNISG--ILIHTSNEFKKSAKAFSSATVLFSINGKDFS--DTIVHFNNPE-----DTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFES 322          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Celegans
Match: ddr-1 (Discoidin domain-containing receptor A [Source:UniProtKB/Swiss-Prot;Acc:Q18163])

HSP 1 Score: 111.309 bits (277), Expect = 7.094e-25
Identity = 107/396 (27.02%), Postives = 173/396 (43.69%), Query Frame = 1
Query:  103 LQI-LVLFSIYFKQIYS--KIDSRSKCGSKLLDDFNL-VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN--DQGLLINGLGRLIDNKTGGNFSLDPNEAMH-YVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFS--DSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            +QI LVL +IY     +  +ID   +CG   L   N  + DS  TASS F   S          P+ AR     +    AWCP+ ++     ++L++ L    +I   +T+GR+  G G+EF+  Y I Y R   S W  YK    N      + G  D        LDPPIV   +R  P S     VC++ ++ GC  E  V  Y     ++P  S L            F+DS F+ +    +  +  GLG L D         + N+  + ++GWNR+    + +  +T+ F F+ V NF+   L  F N    I      +  FS  G  F   + I +   + ++++    D + P     +  + G+ +++ + F S+W+ L+E+ F S
Sbjct:    1 MQIALVLLAIYGTTTTNTLRID---QCGENALGMQNGDIADSQITASSSFDKQS--------VGPQNAR--LHSELASGAWCPKPQINSKSYEFLQVTLNDTFLITSVETQGRYGNGTGREFASHYMIDYLR-PGSQWIRYK----NRTGHVYMDGNFDTTTPVIRVLDPPIVASRIRFVPSSKNTRTVCMRAEIHGCKHEG-VTYY----STVPDGSRLDTLD--------FKDSMFEDSQIYTESGIKRGLGLLTDGFVAQASPFEKNQMNNSWIGWNRD----TTDGRITILFEFEEVHNFTDVVLATFGNRIDGI------DVIFSQDGKTFPLFSQISSSERQSLNNTSRRYDFRVP-----LHNRAGRKVRISIKFSSDWMFLTEVHFTS 350          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Fly
Match: smal (gene:FBgn0085409 transcript:FBtr0329980)

HSP 1 Score: 177.178 bits (448), Expect = 6.583e-46
Identity = 114/375 (30.40%), Postives = 189/375 (50.40%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPN---EAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIG 1278
            + C   L  +  L+ D+  TASS           M    P+ AR     DN   AWCP++ V+ +L++YL++DL +  VI   +T+GR+ +G G+E++  Y ++Y R     W+ +K    N+  +E+L G  + + +    L P I    +RIYP+      VCL+ ++ GC +E+ ++ Y     SIPK       G+   +     D ++DG       ++GLG+L+D + G  NF  D +   +   ++GW RN+      K V + F FD+VRNFS+  L+     T  +   V  +  FS+ G  FS +    +  P+ + D   D     +   +  ++G+YL++ LYF  +WI+LSEI FIS  A+G
Sbjct:   76 ATCNVPLGMESLLITDAQITASS--------AHDMAFVGPQHAR--LKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWK----NIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSY-----SIPK-------GVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLVDGQKGKDNFRTDIHGFGKGYEWIGW-RNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDTIMDHARD-----VTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPAMG 418          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Fly
Match: smal (gene:FBgn0085409 transcript:FBtr0112617)

HSP 1 Score: 177.178 bits (448), Expect = 6.583e-46
Identity = 114/375 (30.40%), Postives = 189/375 (50.40%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPN---EAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIG 1278
            + C   L  +  L+ D+  TASS           M    P+ AR     DN   AWCP++ V+ +L++YL++DL +  VI   +T+GR+ +G G+E++  Y ++Y R     W+ +K    N+  +E+L G  + + +    L P I    +RIYP+      VCL+ ++ GC +E+ ++ Y     SIPK       G+   +     D ++DG       ++GLG+L+D + G  NF  D +   +   ++GW RN+      K V + F FD+VRNFS+  L+     T  +   V  +  FS+ G  FS +    +  P+ + D   D     +   +  ++G+YL++ LYF  +WI+LSEI FIS  A+G
Sbjct:   76 ATCNVPLGMESLLITDAQITASS--------AHDMAFVGPQHAR--LKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWK----NIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSY-----SIPK-------GVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLVDGQKGKDNFRTDIHGFGKGYEWIGW-RNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDTIMDHARD-----VTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPAMG 418          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Fly
Match: smal (gene:FBgn0085409 transcript:FBtr0329979)

HSP 1 Score: 177.178 bits (448), Expect = 1.515e-45
Identity = 114/375 (30.40%), Postives = 189/375 (50.40%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPN---EAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIG 1278
            + C   L  +  L+ D+  TASS           M    P+ AR     DN   AWCP++ V+ +L++YL++DL +  VI   +T+GR+ +G G+E++  Y ++Y R     W+ +K    N+  +E+L G  + + +    L P I    +RIYP+      VCL+ ++ GC +E+ ++ Y     SIPK       G+   +     D ++DG       ++GLG+L+D + G  NF  D +   +   ++GW RN+      K V + F FD+VRNFS+  L+     T  +   V  +  FS+ G  FS +    +  P+ + D   D     +   +  ++G+YL++ LYF  +WI+LSEI FIS  A+G
Sbjct:   76 ATCNVPLGMESLLITDAQITASS--------AHDMAFVGPQHAR--LKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWK----NIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSY-----SIPK-------GVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLVDGQKGKDNFRTDIHGFGKGYEWIGW-RNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDTIMDHARD-----VTIKLHHRVGKYLKINLYFAVKWIMLSEISFISVPAMG 418          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Fly
Match: Ddr (gene:FBgn0053531 transcript:FBtr0344771)

HSP 1 Score: 170.629 bits (431), Expect = 2.768e-43
Identity = 103/355 (29.01%), Postives = 183/355 (51.55%), Query Frame = 1
Query:  226 ASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPN---EAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIG 1278
            A + F  T+ +   M +  P+ AR     DN   AWCP++ V++ L +YL++DL  + +++  +T+GRF +G G+E++  Y I+Y R     W  ++    +L  +EVL G  + + +    L P +    VR+YP+S     VCL+ ++ GC +E+ ++ Y     SIPK       G+   +     D ++DG  +    +NGLG+L+D + G  NF  D N   +   ++GW  + +     + V + F F++VRN S+  ++     +  +   V  +  FS+ G  FS +    +  P+L+ D   D     +   +  ++G+Y+QL LYF + W+++SEI FIS   +G
Sbjct:  116 AIADFQITASSAHDMGNVGPQHAR--LKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWR----SLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSY-----SIPK-------GMQRGMDIDLSDKTYDGYEEGDHYVNGLGQLVDGQRGKDNFRADINGLGKGYEWIGWRNDTLLG---RPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGRHFSGEPVQFSYMPDLVLDHARD-----VTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPVVG 444          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Fly
Match: Ddr (gene:FBgn0053531 transcript:FBtr0344770)

HSP 1 Score: 170.629 bits (431), Expect = 2.768e-43
Identity = 103/355 (29.01%), Postives = 183/355 (51.55%), Query Frame = 1
Query:  226 ASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPN---EAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIG 1278
            A + F  T+ +   M +  P+ AR     DN   AWCP++ V++ L +YL++DL  + +++  +T+GRF +G G+E++  Y I+Y R     W  ++    +L  +EVL G  + + +    L P +    VR+YP+S     VCL+ ++ GC +E+ ++ Y     SIPK       G+   +     D ++DG  +    +NGLG+L+D + G  NF  D N   +   ++GW  + +     + V + F F++VRN S+  ++     +  +   V  +  FS+ G  FS +    +  P+L+ D   D     +   +  ++G+Y+QL LYF + W+++SEI FIS   +G
Sbjct:  116 AIADFQITASSAHDMGNVGPQHAR--LKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWR----SLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSY-----SIPK-------GMQRGMDIDLSDKTYDGYEEGDHYVNGLGQLVDGQRGKDNFRADINGLGKGYEWIGWRNDTLLG---RPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGRHFSGEPVQFSYMPDLVLDHARD-----VTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPVVG 444          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Zebrafish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060323-2])

HSP 1 Score: 162.925 bits (411), Expect = 1.028e-40
Identity = 117/374 (31.28%), Postives = 185/374 (49.47%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPEL---MSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            +KC   L  +  ++PDS  TASS +   S +TE        A          D AWCP   V  S  ++L++DL +L  ++   T+GR A G G+EF+  Y+++Y R +  +W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC+++D +  Y     + P    + LSG   ++ N F DS +DG+ + G++  GLG+L D   GGN  ++  E        YVGWNR  +G   + +V + F F+  R F + +++    HT    Q V++   FS    KF          PEL   +SD   D  S  I   +  +  Q L+    F   W+L+SEI F S
Sbjct:   33 AKCRYALGMEDGVIPDSDITASSAW---SDSTE--------AKHGRLSNGEGDGAWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSR-DGRHWMTWK----DRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAY-----TAPLGHVMDLSG---SLVN-FNDSVYDGSKEGGVIFGGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLG---QPTVDIEFHFEKTRIFHTMQVHSNNRHT----QGVRV---FSEVVCKFKASLLSPWAEPELSLQVSD-LHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISFYS 370          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Zebrafish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060323-2])

HSP 1 Score: 162.925 bits (411), Expect = 1.028e-40
Identity = 117/374 (31.28%), Postives = 185/374 (49.47%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPEL---MSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            +KC   L  +  ++PDS  TASS +   S +TE        A          D AWCP   V  S  ++L++DL +L  ++   T+GR A G G+EF+  Y+++Y R +  +W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC+++D +  Y     + P    + LSG   ++ N F DS +DG+ + G++  GLG+L D   GGN  ++  E        YVGWNR  +G   + +V + F F+  R F + +++    HT    Q V++   FS    KF          PEL   +SD   D  S  I   +  +  Q L+    F   W+L+SEI F S
Sbjct:   33 AKCRYALGMEDGVIPDSDITASSAW---SDSTE--------AKHGRLSNGEGDGAWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSR-DGRHWMTWK----DRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAY-----TAPLGHVMDLSG---SLVN-FNDSVYDGSKEGGVIFGGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLG---QPTVDIEFHFEKTRIFHTMQVHSNNRHT----QGVRV---FSEVVCKFKASLLSPWAEPELSLQVSD-LHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISFYS 370          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Zebrafish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060323-2])

HSP 1 Score: 162.54 bits (410), Expect = 1.194e-40
Identity = 117/374 (31.28%), Postives = 185/374 (49.47%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPEL---MSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            +KC   L  +  ++PDS  TASS +   S +TE        A          D AWCP   V  S  ++L++DL +L  ++   T+GR A G G+EF+  Y+++Y R +  +W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC+++D +  Y     + P    + LSG   ++ N F DS +DG+ + G++  GLG+L D   GGN  ++  E        YVGWNR  +G   + +V + F F+  R F + +++    HT    Q V++   FS    KF          PEL   +SD   D  S  I   +  +  Q L+    F   W+L+SEI F S
Sbjct:   33 AKCRYALGMEDGVIPDSDITASSAW---SDSTE--------AKHGRLSNGEGDGAWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSR-DGRHWMTWK----DRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAY-----TAPLGHVMDLSG---SLVN-FNDSVYDGSKEGGVIFGGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLG---QPTVDIEFHFEKTRIFHTMQVHSNNRHT----QGVRV---FSEVVCKFKASLLSPWAEPELSLQVSD-LHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISFYS 370          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Zebrafish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060323-2])

HSP 1 Score: 162.155 bits (409), Expect = 1.429e-40
Identity = 117/374 (31.28%), Postives = 185/374 (49.47%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPEL---MSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            +KC   L  +  ++PDS  TASS +   S +TE        A          D AWCP   V  S  ++L++DL +L  ++   T+GR A G G+EF+  Y+++Y R +  +W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC+++D +  Y     + P    + LSG   ++ N F DS +DG+ + G++  GLG+L D   GGN  ++  E        YVGWNR  +G   + +V + F F+  R F + +++    HT    Q V++   FS    KF          PEL   +SD   D  S  I   +  +  Q L+    F   W+L+SEI F S
Sbjct:   33 AKCRYALGMEDGVIPDSDITASSAW---SDSTE--------AKHGRLSNGEGDGAWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSR-DGRHWMTWK----DRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAY-----TAPLGHVMDLSG---SLVN-FNDSVYDGSKEGGVIFGGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLG---QPTVDIEFHFEKTRIFHTMQVHSNNRHT----QGVRV---FSEVVCKFKASLLSPWAEPELSLQVSD-LHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISFYS 370          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Zebrafish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060323-2])

HSP 1 Score: 143.665 bits (361), Expect = 1.249e-37
Identity = 91/286 (31.82%), Postives = 150/286 (52.45%), Query Frame = 1
Query:  166 SKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKL 1008
            +KC   L  +  ++PDS  TASS +   S +TE        A          D AWCP   V  S  ++L++DL +L  ++   T+GR A G G+EF+  Y+++Y R +  +W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC+++D +  Y     + P    + LSG   ++ N F DS +DG+ + G++  GLG+L D   GGN  ++  E        YVGWNR  +G   + +V + F F+  R F + ++
Sbjct:   33 AKCRYALGMEDGVIPDSDITASSAW---SDSTE--------AKHGRLSNGEGDGAWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSR-DGRHWMTWK----DRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAY-----TAPLGHVMDLSG---SLVN-FNDSVYDGSKEGGVIFGGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLG---QPTVDIEFHFEKTRIFHTMQV 290          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Xenopus
Match: DDR2 (discoidin domain receptor tyrosine kinase 2 [Source:NCBI gene;Acc:100497889])

HSP 1 Score: 132.109 bits (331), Expect = 5.772e-31
Identity = 109/378 (28.84%), Postives = 184/378 (48.68%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKV-AQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPNEAM----HYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLP 1320
            +PD   TASS +  ++         + K  R   D +  D AWCP   V  + L ++L+IDL  L  I    T+GR A G G EF+  +KI Y R+ T  W  ++    N   R+VL G  +P+    + L+PPIV R++R  P +   M VCL+++L+GC++ D ++ Y    G      FL   G   A+Y    D+ +DG      +  GLG+L D  +G  +F+L     M     YVGW+ NE  S +   V + F FD +RNF++ K++     +  +     ++  F    +++ + N+I   +  L+ D  ++  + ++   +   + + ++   YF   W++ SEI F S+ A+ Y+    P     +P
Sbjct:    6 IPDEDITASSQWSEST---------AAKYGR--LDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDGT-RWISWR----NRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSG----QQFLLPEGY--AIY--LNDTIYDGAIGYS-MTEGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWS-NE--SFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEW-EANSI---SSTLVLDD-ANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAM-YNNSMNPPQPASVP 349          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Xenopus
Match: DDR2 (discoidin domain receptor tyrosine kinase 2 [Source:NCBI gene;Acc:100497889])

HSP 1 Score: 132.109 bits (331), Expect = 6.884e-31
Identity = 109/378 (28.84%), Postives = 184/378 (48.68%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKV-AQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPNEAM----HYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLP 1320
            +PD   TASS +  ++         + K  R   D +  D AWCP   V  + L ++L+IDL  L  I    T+GR A G G EF+  +KI Y R+ T  W  ++    N   R+VL G  +P+    + L+PPIV R++R  P +   M VCL+++L+GC++ D ++ Y    G      FL   G   A+Y    D+ +DG      +  GLG+L D  +G  +F+L     M     YVGW+ NE  S +   V + F FD +RNF++ K++     +  +     ++  F    +++ + N+I   +  L+ D  ++  + ++   +   + + ++   YF   W++ SEI F S+ A+ Y+    P     +P
Sbjct:   38 IPDEDITASSQWSEST---------AAKYGR--LDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDGT-RWISWR----NRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSG----QQFLLPEGY--AIY--LNDTIYDGAIGYS-MTEGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWS-NE--SFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEW-EANSI---SSTLVLDD-ANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAM-YNNSMNPPQPASVP 381          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Xenopus
Match: DDR2 (discoidin domain receptor tyrosine kinase 2 [Source:NCBI gene;Acc:100497889])

HSP 1 Score: 131.724 bits (330), Expect = 7.695e-31
Identity = 109/378 (28.84%), Postives = 184/378 (48.68%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKV-AQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPNEAM----HYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLP 1320
            +PD   TASS +  ++         + K  R   D +  D AWCP   V  + L ++L+IDL  L  I    T+GR A G G EF+  +KI Y R+ T  W  ++    N   R+VL G  +P+    + L+PPIV R++R  P +   M VCL+++L+GC++ D ++ Y    G      FL   G   A+Y    D+ +DG      +  GLG+L D  +G  +F+L     M     YVGW+ NE  S +   V + F FD +RNF++ K++     +  +     ++  F    +++ + N+I   +  L+ D  ++  + ++   +   + + ++   YF   W++ SEI F S+ A+ Y+    P     +P
Sbjct:    6 IPDEDITASSQWSEST---------AAKYGR--LDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDGT-RWISWR----NRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSG----QQFLLPEGY--AIY--LNDTIYDGAIGYS-MTEGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWS-NE--SFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEW-EANSI---SSTLVLDD-ANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAM-YNNSMNPPQPASVP 349          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Xenopus
Match: ddr2l (discoidin domain receptor tyrosine kinase 2 like [Source:NCBI gene;Acc:779954])

HSP 1 Score: 131.724 bits (330), Expect = 8.497e-31
Identity = 103/378 (27.25%), Postives = 178/378 (47.09%), Query Frame = 1
Query:  280 SPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVF-QDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGW-NRNEIGSSNEKS----VTLWFRFDSVRNFSSAKLYI--FENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSP---WIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDT------KSEPILSTDLPL-LEKSTKSISENS 1359
             P+ AR    ++  D AWCP   +      YL+IDL  L  I    T+GR A+  GKEF+  Y++ Y R     W  ++    +   ++V++G  D +      L PPI+ R++R+ P +   M VC++++L+GC + D +  Y + EG          + I P     F  DS++DG  ++     GLG+L D   G +   D  +++ Y  W   + IG  N+ +    V + F FD  RNFS  K++     +  +KI Q  +   K  L G+  ++   ++            D K+P   ++   +++++G  +  + YF   W++ SEI F S+  I   T       S P  +T++P+ L+ ST+   E +
Sbjct:   51 GPQYAR--LQREEGDGAWCPAGLLQPEDVQYLQIDLHELHFITLIGTQGRHARATGKEFARAYRVDYSRN-GGRWLSWR----DHQGQQVMRGNVDEYEVVLADLRPPIIARYIRVIPVTKVPMTVCMRVELYGCKWSDGLTSYSVPEGE---------TYIAPGQPIAFLNDSTYDGYLEKRRQFGGLGQLTDGIHGLD---DFTQSLQYRVWPGYDYIGWRNDSAPRGYVEVEFHFDRPRNFSLMKVHCNNLFSKGVKIFQKAECLFKPRLEGEWEAEPVVVLM---------VVDDKNPSARFVTIPLRQRVGSAILCRFYFADAWMMFSEISFESDMGIAVPTLGTQSPTSAPAQTTEVPVALQNSTERKLETT 400          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Xenopus
Match: DDR2 (discoidin domain receptor tyrosine kinase 2 [Source:NCBI gene;Acc:100497889])

HSP 1 Score: 128.642 bits (322), Expect = 6.237e-30
Identity = 102/354 (28.81%), Postives = 172/354 (48.59%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKV-AQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            +PD   TASS +  ++         + K  R   D +  D AWCP   V  + L ++L+IDL  L  I    T+GR A G G EF+  +KI Y R+ T  W  ++    N   R+VL G  +P+    + L+PPIV R++R  P +   M VCL+++L+GC++ D ++ Y    G      FL   G   A+Y    D+ +DG    G L +G+  L D      + + P     YVGW+ NE  S +   V + F FD +RNF++ K++     +  +     ++  F    +++ + N+I   +  L+ D  ++  + ++   +   + + ++   YF   W++ SEI F S
Sbjct:    6 IPDEDITASSQWSEST---------AAKYGR--LDSEGGDGAWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDGT-RWISWR----NRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSG----QQFLLPEGY--AIY--LNDTIYDGAIGLGQLTDGVSGLDDFTLTHEYHMWP--GYDYVGWS-NE--SFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEW-EANSI---SSTLVLDD-ANPSARYVTVQLHNHMARAIKCHYYFADSWMMFSEITFQS 325          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Mouse
Match: Ddr1 (discoidin domain receptor family, member 1 [Source:MGI Symbol;Acc:MGI:99216])

HSP 1 Score: 146.362 bits (368), Expect = 2.971e-36
Identity = 98/328 (29.88%), Postives = 157/328 (47.87%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDG-------TNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    +QLS     V     DS++DG           G L +G+  L D +      + P     YVGW+     +     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +      +  S  D ++  I   +   +G++LQ +  F   W+L SEI FIS+ 
Sbjct:   66 ESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMDWK----DRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMQLS----EVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWP--GYDYVGWSNQSFPTG---YVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPAMAWEGEPVR---HALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDV 370          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Mouse
Match: Ddr1 (discoidin domain receptor family, member 1 [Source:MGI Symbol;Acc:MGI:99216])

HSP 1 Score: 145.976 bits (367), Expect = 1.730e-35
Identity = 98/329 (29.79%), Postives = 157/329 (47.72%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDG-------TNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETA 1272
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    +QLS     V     DS++DG           G L +G+  L D +      + P     YVGW+     +     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +      +  S  D ++  I   +   +G++LQ +  F   W+L SEI FIS+  
Sbjct:   66 ESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMDWK----DRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMQLS----EVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWP--GYDYVGWSNQSFPTG---YVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPAMAWEGEPVRHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDVV 371          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Mouse
Match: Ddr1 (discoidin domain receptor family, member 1 [Source:MGI Symbol;Acc:MGI:99216])

HSP 1 Score: 146.362 bits (368), Expect = 1.783e-35
Identity = 98/328 (29.88%), Postives = 157/328 (47.87%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDG-------TNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    +QLS     V     DS++DG           G L +G+  L D +      + P     YVGW+     +     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +      +  S  D ++  I   +   +G++LQ +  F   W+L SEI FIS+ 
Sbjct:   66 ESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMDWK----DRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMQLS----EVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWP--GYDYVGWSNQSFPTG---YVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPAMAWEGEPVRHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDV 370          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Mouse
Match: Ddr1 (discoidin domain receptor family, member 1 [Source:MGI Symbol;Acc:MGI:99216])

HSP 1 Score: 146.362 bits (368), Expect = 1.783e-35
Identity = 98/328 (29.88%), Postives = 157/328 (47.87%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDG-------TNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    +QLS     V     DS++DG           G L +G+  L D +      + P     YVGW+     +     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +      +  S  D ++  I   +   +G++LQ +  F   W+L SEI FIS+ 
Sbjct:   66 ESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMDWK----DRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMQLS----EVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWP--GYDYVGWSNQSFPTG---YVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPAMAWEGEPVRHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDV 370          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Mouse
Match: Ddr1 (discoidin domain receptor family, member 1 [Source:MGI Symbol;Acc:MGI:99216])

HSP 1 Score: 146.362 bits (368), Expect = 1.783e-35
Identity = 98/328 (29.88%), Postives = 157/328 (47.87%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDG-------TNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    +QLS     V     DS++DG           G L +G+  L D +      + P     YVGW+     +     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +      +  S  D ++  I   +   +G++LQ +  F   W+L SEI FIS+ 
Sbjct:   66 ESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMDWK----DRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMQLS----EVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWP--GYDYVGWSNQSFPTG---YVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPAMAWEGEPVRHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDV 370          
BLAST of Discoidin domain-containing receptor 2 vs. UniProt/SwissProt
Match: sp|Q63474|DDR1_RAT (Epithelial discoidin domain-containing receptor 1 OS=Rattus norvegicus OX=10116 GN=Ddr1 PE=2 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 4.116e-35
Identity = 100/328 (30.49%), Postives = 161/328 (49.09%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDG-------TNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    +QLS +   VY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R+F + +++    HTL    P  +E +F   G   + +   +      +  S  D ++  I   +   +G++LQ +  F   W+L SEI FIS+ 
Sbjct:   66 ESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMDWK----DRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMQLSEM---VY--LNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWP--GYDYVGWSNHSFPSG---YVEMEFEFDRLRSFQTMQVHCNNMHTLGARLPGGVECRFK-RGPAMAWEGEPVHHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDV 369          
BLAST of Discoidin domain-containing receptor 2 vs. UniProt/SwissProt
Match: sp|Q03146|DDR1_MOUSE (Epithelial discoidin domain-containing receptor 1 OS=Mus musculus OX=10090 GN=Ddr1 PE=2 SV=2)

HSP 1 Score: 146.362 bits (368), Expect = 1.247e-34
Identity = 98/328 (29.88%), Postives = 157/328 (47.87%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDG-------TNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    +QLS     V     DS++DG           G L +G+  L D +      + P     YVGW+     +     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +      +  S  D ++  I   +   +G++LQ +  F   W+L SEI FIS+ 
Sbjct:   66 ESSDGDGAWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMDWK----DRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMQLS----EVMVHLNDSTYDGYTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWP--GYDYVGWSNQSFPTG---YVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRFK-RGPAMAWEGEPVRHA---LGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISDV 370          
BLAST of Discoidin domain-containing receptor 2 vs. UniProt/SwissProt
Match: sp|Q08345|DDR1_HUMAN (Epithelial discoidin domain-containing receptor 1 OS=Homo sapiens OX=9606 GN=DDR1 PE=1 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 3.010e-34
Identity = 98/328 (29.88%), Postives = 160/328 (48.78%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN-------DQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            +  + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    + LS    AVY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +  N   +  +  D ++  +   +  ++ ++LQ +  F   W+L SEI FIS+ 
Sbjct:   65 ESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMGWK----DRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMYLS---EAVY--LNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWP--GYDYVGWSNHSFSSG---YVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPAMAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDV 368          
BLAST of Discoidin domain-containing receptor 2 vs. UniProt/SwissProt
Match: sp|Q7YR43|DDR1_PANTR (Epithelial discoidin domain-containing receptor 1 OS=Pan troglodytes OX=9598 GN=DDR1 PE=3 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 4.431e-34
Identity = 98/325 (30.15%), Postives = 159/325 (48.92%), Query Frame = 1
Query:  316 NQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTN-------DQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISET 1269
            + D AWCP   V    E+YL++DL RL ++    T+GR A G GKEFS  Y+++Y R +   W  +K    +   +EV+ G  DP     + L PP+V R VR YP +  +M VCL+++L+GC++ D ++ Y     + P    + LS    AVY    DS++DG           G L +G+  L D +      + P     YVGW+ +   S     V + F FD +R F + +++    HTL    P  +E +F   G   + +   +  N   +  +  D ++  +   +  ++ ++LQ +  F   W+L SEI FIS+ 
Sbjct:   64 DGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSR-DGRRWMGWK----DRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSY-----TAPVGQTMYLS---EAVY--LNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWP--GYDYVGWSNHSFSSG---YVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFR-RGPAMAWEGEPMRHN---LGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDV 364          
BLAST of Discoidin domain-containing receptor 2 vs. UniProt/SwissProt
Match: sp|Q16832|DDR2_HUMAN (Discoidin domain-containing receptor 2 OS=Homo sapiens OX=9606 GN=DDR2 PE=1 SV=2)

HSP 1 Score: 136.346 bits (342), Expect = 1.434e-31
Identity = 109/374 (29.14%), Postives = 185/374 (49.47%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKV-AQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGS---IPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEP 1299
            +PD   TASS +   S +T      + K  R   D +  D AWCP   V    L+++L+IDL  L  I    T+GR A G G EF+P YKI Y R+ T  W  ++    N   ++VL G ++P+    + L+PPIV R+VR  P +   M VC++++L+GC++ D ++ Y    G    +P  S + L+           DS +DG      +  GLG+L D  +G +     +E        YVGW RNE  S+    + + F FD +RNF++ K++   N+    ++ VK+  +   Y    + +    A +  L+ D  + S   ++   +  ++   ++ + +F   W++ SEI F S+ A+  ++++ P
Sbjct:   41 IPDEDITASSQW---SEST------AAKYGR--LDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGT-RWISWR----NRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLN-----------DSVYDGAVGYS-MTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGW-RNE--SATNGYIEIMFEFDRIRNFTTMKVHC--NNMF--AKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSAR-FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSEALP 378          
BLAST of Discoidin domain-containing receptor 2 vs. TrEMBL
Match: A0A4Z2D7M2 (Discoidin domain-containing receptor 2 isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_003721 PE=4 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 9.071e-55
Identity = 137/412 (33.25%), Postives = 209/412 (50.73%), Query Frame = 1
Query:  163 RSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETS-NWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIP----------------------KNSFLQLSGIYPAVYNVFQDSSFDGTNDQ--GLLINGLGRLIDNKTGG---------NFSLDPNEAMHYVGWNRNEIGSSNEKS---VTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIA----ENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAI 1275
            ++KC   LL + + +PDSAF A+S  +  S        +S  + R     +N D+AWCP  ++    ++Y+EID+G L +I      G  A+G G  ++P++ I+Y+RE+ + NW+ Y++    +  R  L G  D  +  +  LDPP++ RW+RIYP+      VC++L+ +GC F D ++EYRI EGS+                       K++F Q  G  P     F D+ +DG   +   LL  GLG LID  +              +D      +VGW+R+   SS ++    V + FRF SVRNF+  +LYI  N+  KI  P ++E KFS+ G  FS ++ I      EN  L    FS      I  ++  +IGQ +QLK +F  EW+L SEI F S+  I
Sbjct:   82 KTKCIQSLLVNRHQIPDSAFNATSEVVDPSGAKR----YSAHSIR----NENTDFAWCPGKRIGTDCDEYVEIDMGELNIITKVVISGLLAEGGGSRYTPYFYIRYKREQNAENWRTYRQLRPIIISR--LLGGLDALVPKFVVLDPPLIARWIRIYPYRDTPGFVCIRLEAYGCRFSDDLVEYRIPEGSLAQPPYQAETDLYQSQGAELFVHEKSNFSQAGGGLP-----FSDTCYDGHRIEPGSLLDGGLGCLIDLNSASRDTIPSIEQRLKVDKLVNYQFVGWHRDRWRSSQDRDNGVVDMLFRFASVRNFTRLRLYISNNYLEKIRLPRRLEVKFSVGGVHFSGQSPISRDFKLENRSL--GVFS------IIMDLSHRIGQVVQLKAFFADEWLLFSEIRFESDKVI 470          
BLAST of Discoidin domain-containing receptor 2 vs. TrEMBL
Match: A0A4Z2D7P0 (Discoidin domain-containing receptor 2 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_003721 PE=4 SV=1)

HSP 1 Score: 215.698 bits (548), Expect = 3.005e-54
Identity = 137/412 (33.25%), Postives = 209/412 (50.73%), Query Frame = 1
Query:  163 RSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETS-NWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIP----------------------KNSFLQLSGIYPAVYNVFQDSSFDGTNDQ--GLLINGLGRLIDNKTGG---------NFSLDPNEAMHYVGWNRNEIGSSNEKS---VTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIA----ENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAI 1275
            ++KC   LL + + +PDSAF A+S  +  S        +S  + R     +N D+AWCP  ++    ++Y+EID+G L +I      G  A+G G  ++P++ I+Y+RE+ + NW+ Y++    +  R  L G  D  +  +  LDPP++ RW+RIYP+      VC++L+ +GC F D ++EYRI EGS+                       K++F Q  G  P     F D+ +DG   +   LL  GLG LID  +              +D      +VGW+R+   SS ++    V + FRF SVRNF+  +LYI  N+  KI  P ++E KFS+ G  FS ++ I      EN  L    FS      I  ++  +IGQ +QLK +F  EW+L SEI F S+  I
Sbjct:   82 KTKCIQSLLVNRHQIPDSAFNATSEVVDPSGAKR----YSAHSIR----NENTDFAWCPGKRIGTDCDEYVEIDMGELNIITKVVISGLLAEGGGSRYTPYFYIRYKREQNAENWRTYRQLRPIIISR--LLGGLDALVPKFVVLDPPLIARWIRIYPYRDTPGFVCIRLEAYGCRFSDDLVEYRIPEGSLAQPPYQAETDLYQSQGAELFVHEKSNFSQAGGGLP-----FSDTCYDGHRIEPGSLLDGGLGCLIDLNSASRDTIPSIEQRLKVDKLVNYQFVGWHRDRWRSSQDRDNGVVDMLFRFASVRNFTRLRLYISNNYLEKIRLPRRLEVKFSVGGVHFSGQSPISRDFKLENRSL--GVFS------IIMDLSHRIGQVVQLKAFFADEWLLFSEIRFESDKVI 470          
BLAST of Discoidin domain-containing receptor 2 vs. TrEMBL
Match: A0A183QKB0 (F5/8 type C domain-containing protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1)

HSP 1 Score: 215.698 bits (548), Expect = 3.115e-54
Identity = 145/447 (32.44%), Postives = 225/447 (50.34%), Query Frame = 1
Query:  163 RSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRRE-ETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPA----VYNV-------------FQDSSFDGTNDQ--GLLINGLGRLID-------------NKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKS---VTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIA----ENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLPLL-EKSTKSISENSQSQVDST 1380
            ++KC   LL + + +PDSAF A+S  +  S        ++  + R     +N D+AWCP  +++   ++Y+EID+G L +I      G  A+G G  ++P++ I+Y+RE    NW+ Y++    +  R  L G  D  +  +  LDPP++ RW+RIYP+      VC++L+ +GC F D ++EYRI EGS+    +   + +Y +    V+N              F D+ +DG   +   LL  GLG LID                G +   D +    +VGW+R+   SS +K    V + FRF SVRNF+  +LYI  N+  KI  P ++E KFS+ G  FS +  I      EN  L    FS      I  ++  +IGQ +QLK +F  +W+L SEI F SE        + PI   +L +L EKS+   S N +  + +T
Sbjct:   55 KTKCIQSLLVNRHQIPDSAFNATSEVVDPSGAKR----YNAHSIR----NENTDFAWCPGKRISTECDEYVEIDMGELNIITKVVISGLLAEGGGSRYTPYFYIRYKREINEENWRTYRQLRPTIISR--LLGGLDALVPKFVVLDPPLIARWIRIYPYRDTPGFVCIRLEAYGCRFSDDLVEYRIPEGSLAHPPYQAETNLYKSQGSEVFNTEKLNSSQAGGGLPFSDTCYDGHRIEPGSLLDGGLGCLIDLNSANRDTIPSIRQTVGVSSKADSSMNHQFVGWHRDRWKSSQDKDNDVVDMLFRFASVRNFTRLRLYISNNYLEKIRLPRRLEVKFSVGGVHFSGQLPISREFKLENRSL--GVFS------IILDLSHRIGQVVQLKAFFADDWLLFSEIRFESEKV------TTPIKIDELAMLSEKSSNHQSINEEEDLMNT 477          
BLAST of Discoidin domain-containing receptor 2 vs. TrEMBL
Match: G4V7C2 (Putative discoidin domain receptor OS=Schistosoma mansoni OX=6183 GN=Smp_150730 PE=4 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 9.067e-54
Identity = 144/447 (32.21%), Postives = 224/447 (50.11%), Query Frame = 1
Query:  163 RSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRRE-ETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPA----VYNV-------------FQDSSFDGTNDQ--GLLINGLGRLID-------------NKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKS---VTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIA----ENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLPLL-EKSTKSISENSQSQVDST 1380
            ++KC   LL + + +PDSAF A+S  +  S        ++  + R     +N D+AWCP  +++   ++Y+EID+G L +I      G  A+G G  ++P++ I+Y+RE    NW+ Y++    +  R  L G  D  +  +  LDPP++ RW+RIYP+      VC++L+ +GC F D ++EYRI EGS+    +   + +Y +    V+               F D+ +DG   +   LL  GLG LID                G +   D +    +VGW+R+   SS +K    V + FRF SVRNF+  +LYI  N+  KI  P ++E KFS+ G  FS +  I      EN  L    FS      I  ++  +IGQ +QLK +F  +W+L SEI F SE        + PI   +L +L EKS+   S N +  + +T
Sbjct:   53 KTKCIQSLLVNRHQIPDSAFNATSEVVDPSGAKR----YNAHSIR----NENTDFAWCPGKRISTECDEYVEIDMGELNIITKVVISGLLAEGGGSRYTPYFYIRYKREINEENWRTYRQLRPTIISR--LLGGLDALVPKFVVLDPPLIARWIRIYPYRDTPGFVCIRLEAYGCRFSDDLVEYRIPEGSLAHPPYQAETNLYKSQGSEVFTTEKLNSSQAGGGLPFSDTCYDGHRIEPGSLLDGGLGCLIDLNSANRDTIPSIRQTVGVSSKADSSMNHQFVGWHRDRWKSSQDKDNDVVDMLFRFASVRNFTRLRLYISNNYLEKIRLPRRLEVKFSVGGVHFSGQLPISREFKLENRSL--GVFS------IILDLSHRIGQVVQLKAFFADDWLLFSEIRFESEKV------TTPIKIDELAMLSEKSSNHQSINEEEDLMNT 475          
BLAST of Discoidin domain-containing receptor 2 vs. TrEMBL
Match: A0A5K4FC05 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 1.471e-53
Identity = 144/447 (32.21%), Postives = 224/447 (50.11%), Query Frame = 1
Query:  163 RSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRRE-ETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPA----VYNV-------------FQDSSFDGTNDQ--GLLINGLGRLID-------------NKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKS---VTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIA----ENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLPLL-EKSTKSISENSQSQVDST 1380
            ++KC   LL + + +PDSAF A+S  +  S        ++  + R     +N D+AWCP  +++   ++Y+EID+G L +I      G  A+G G  ++P++ I+Y+RE    NW+ Y++    +  R  L G  D  +  +  LDPP++ RW+RIYP+      VC++L+ +GC F D ++EYRI EGS+    +   + +Y +    V+               F D+ +DG   +   LL  GLG LID                G +   D +    +VGW+R+   SS +K    V + FRF SVRNF+  +LYI  N+  KI  P ++E KFS+ G  FS +  I      EN  L    FS      I  ++  +IGQ +QLK +F  +W+L SEI F SE        + PI   +L +L EKS+   S N +  + +T
Sbjct:   88 KTKCIQSLLVNRHQIPDSAFNATSEVVDPSGAKR----YNAHSIR----NENTDFAWCPGKRISTECDEYVEIDMGELNIITKVVISGLLAEGGGSRYTPYFYIRYKREINEENWRTYRQLRPTIISR--LLGGLDALVPKFVVLDPPLIARWIRIYPYRDTPGFVCIRLEAYGCRFSDDLVEYRIPEGSLAHPPYQAETNLYKSQGSEVFTTEKLNSSQAGGGLPFSDTCYDGHRIEPGSLLDGGLGCLIDLNSANRDTIPSIRQTVGVSSKADSSMNHQFVGWHRDRWKSSQDKDNDVVDMLFRFASVRNFTRLRLYISNNYLEKIRLPRRLEVKFSVGGVHFSGQLPISREFKLENRSL--GVFS------IILDLSHRIGQVVQLKAFFADDWLLFSEIRFESEKV------TTPIKIDELAMLSEKSSNHQSINEEEDLMNT 510          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Cavefish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:NCBI gene;Acc:103035361])

HSP 1 Score: 147.132 bits (370), Expect = 9.368e-36
Identity = 98/324 (30.25%), Postives = 162/324 (50.00%), Query Frame = 1
Query:  322 DYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSG--IYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHT--LKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISE 1266
            D AWCP   V  S  ++L+++L +L  ++   T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + LSG  IY        DS +DG+ + G L  GLG+L D   GG+  ++  E        YVGW+R  +G   + +V + F F+  R F   +++    HT  +++   V  E K SL  D +++    +    E + D  S S    +   +  +  Q L+    F   W+L+SEI F SE
Sbjct:   93 DGAWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRD-GRQWITWK----DRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----AAPMGHVMHLSGSPIY------LNDSIYDGSIEAGTLFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALG---QPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLL-DHWTEPALKLRVPLEDLKDPSSRS----VDLPLGGRPAQILRCHFAFADRWLLISEISFNSE 392          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Cavefish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:NCBI gene;Acc:103035361])

HSP 1 Score: 146.747 bits (369), Expect = 1.010e-35
Identity = 98/324 (30.25%), Postives = 162/324 (50.00%), Query Frame = 1
Query:  322 DYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSG--IYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHT--LKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISE 1266
            D AWCP   V  S  ++L+++L +L  ++   T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + LSG  IY        DS +DG+ + G L  GLG+L D   GG+  ++  E        YVGW+R  +G   + +V + F F+  R F   +++    HT  +++   V  E K SL  D +++    +    E + D  S S    +   +  +  Q L+    F   W+L+SEI F SE
Sbjct:   74 DGAWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRD-GRQWITWK----DRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----AAPMGHVMHLSGSPIY------LNDSIYDGSIEAGTLFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALG---QPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLL-DHWTEPALKLRVPLEDLKDPSSRS----VDLPLGGRPAQILRCHFAFADRWLLISEISFNSE 373          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Cavefish
Match: ddr1 (discoidin domain receptor tyrosine kinase 1 [Source:NCBI gene;Acc:103035361])

HSP 1 Score: 146.362 bits (368), Expect = 1.158e-35
Identity = 98/324 (30.25%), Postives = 162/324 (50.00%), Query Frame = 1
Query:  322 DYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSG--IYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHT--LKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISE 1266
            D AWCP   V  S  ++L+++L +L  ++   T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  + +    + L PPI+ R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + LSG  IY        DS +DG+ + G L  GLG+L D   GG+  ++  E        YVGW+R  +G   + +V + F F+  R F   +++    HT  +++   V  E K SL  D +++    +    E + D  S S    +   +  +  Q L+    F   W+L+SEI F SE
Sbjct:   74 DGAWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRD-GRQWITWK----DRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----AAPMGHVMHLSGSPIY------LNDSIYDGSIEAGTLFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALG---QPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLL-DHWTEPALKLRVPLEDLKDPSSRS----VDLPLGGRPAQILRCHFAFADRWLLISEISFNSE 373          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Cavefish
Match: ENSAMXT00000019857.2 (discoidin domain-containing receptor 2-like [Source:NCBI gene;Acc:103025914])

HSP 1 Score: 132.88 bits (333), Expect = 2.332e-31
Identity = 102/337 (30.27%), Postives = 169/337 (50.15%), Query Frame = 1
Query:  307 DKDNQDYAWCPRNKV-AQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTG-GNFSLDPNEAM----HYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEP 1299
            D D+ D AWCP     A+SL+++L+IDL  L  +    T+GR A G G EF+  Y+I+Y R+    W  +   D N G  +V+ G  +P+    + L+PPI+ R+VR  P S   M VC++++L+GC + D ++ Y     S P    +    ++  VY    D+ +DGT D   +  GLG+L D   G  NF+      +     YVGW      S    SV + F FD VRNF+S K++    +T  +    +    F    D  ++    ++  PE  +D+ +++ + ++   +  ++   ++ +  F   W++ SEI F S TA+ Y+T   P
Sbjct:   60 DFDDGDGAWCPDVVAEAKSLKEFLQIDLRTLHFVTLVGTQGRHADGMGNEFAQSYRIKYSRDGV-RWVSWH--DRNGG--QVIDGNKNPYEVVLKDLEPPIIARFVRFMPVSDPSMTVCMRVELYGCEWLDGLVSY-----SAPVGQEMTFQNLH--VY--LNDTVYDGTVDHS-MTEGLGQLTDGSWGLDNFTQSQVYGVWPGYDYVGWTNASFPSG---SVEMVFEFDRVRNFTSMKVHCNNMYTSGVRAFQQAVCYFRSESDWEARP---VSFKPE--ADN-TNTSARFVTVALGHRMASAIKCRFAFSDAWMMFSEIAFQSGTAV-YNTSLIP 371          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Cavefish
Match: ddr2a (discoidin domain receptor tyrosine kinase 2 [Source:NCBI gene;Acc:103037878])

HSP 1 Score: 118.242 bits (295), Expect = 8.615e-27
Identity = 104/346 (30.06%), Postives = 163/346 (47.11%), Query Frame = 1
Query:  307 DKDNQDYAWCPR-NKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGN---FSLDPN--EAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDT-----KSEPILST 1311
            D +  D AWCP      ++++++L+IDL  L  I    T+GR A G G EF+  YKI+Y R+  S W  ++    N   ++V++G  + +    + L PPI+ R+VR  P     M VC++++L+GC + D ++ Y    G   +   L    IY        DS +DG      +  GLG+L D   G +   FS   N      YVGW  NE  S     V + F FD  RNF++ K++   N+    SQ VK   K   Y    S           ++ D    ++  ++  ++   +   ++ + YF   W++ SEI F S+TA+ Y+T     KS P  ST
Sbjct:   72 DCEEGDGAWCPEIPGEPENMKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQTYKIKYSRD-GSRWISWR----NRHGKQVIEGNRNAYDVVLQDLQPPIIARFVRFMPVIDHSMNVCMRVELYGCEWLDGLVSYNAPLG---QKMILHSQPIY------LNDSVYDGAMSYS-MTEGLGQLTDGMCGLDDFTFSHVYNVWPGYDYVGWT-NE--SFPNGYVEIMFEFDRTRNFTTMKVHC--NNMF--SQRVKTFQKVVCYFRSESDWEPTPVSFSPVVDDVNPSAR--FVTVSLNNHMASAIKCQYYFSDMWMMFSEITFQSDTAM-YNTTLIPPKSGPPTST 392          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007840.1 (pep scaffold:Pmarinus_7.0:GL477602:191978:197608:1 gene:ENSPMAG00000007091.1 transcript:ENSPMAT00000007840.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 9.408e-11
Identity = 32/103 (31.07%), Postives = 53/103 (51.46%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLY 513
            +PD   TASS +  T+         +   AR   D +  D AWCP   ++    ++L++DL  L  I    T+GR A+G G E++  Y+++Y R + S W ++
Sbjct:   15 IPDEDITASSQWYETT---------AAHYAR--LDSEEGDGAWCPLGSISPQSMEFLQVDLRELHFITLVGTQGRHAEGTGNEYATAYRLEYSR-DGSRWVMW 105          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001939.1 (pep scaffold:Pmarinus_7.0:GL476444:333387:405756:1 gene:ENSPMAG00000001736.1 transcript:ENSPMAT00000001939.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 2.199e-10
Identity = 70/278 (25.18%), Postives = 121/278 (43.53%), Query Frame = 1
Query:  121 FSIYFKQIYSKIDSRSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSN---WKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGL-LINGLGRLIDNKTGGNFSLDPNEAMHYVG-WNRNEIGS 939
            FS  ++ I  KI    KC   L  +   + D   TASS +           ++ PK AR     +N  +AW P    A S +++++ DLG L +++   T+G  ++ + K    +Y   Y+ E +SN   W + K     +    +L+  +D           P++TR+VR+ P S+E   + L+ +L+GC    H+ +Y               SG+   +    QD     ++ +GL       RL+ +  G    + P+ A H VG W + E+G 
Sbjct:  176 FSATYRMIQRKIIETVKCNQPLGMESLEIRDEQITASSMY--------PNKEWMPKQAR----LNNPVHAWTP---AADSNKEWIQADLGYLKILSGIATQGAISKDSKKS---YYVTSYKMEVSSNGDDWMMLKEGITII----ILRNNSDASSLVENKFSEPVLTRFVRVRPRSWE-NGIALRFELYGC----HISDY-------------PCSGMLGMLSGRIQDGQLQSSSQRGLNWAPSSARLLSSAYGWA-PMPPHGASHPVGEWLQVELGG 412          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004027.1 (pep scaffold:Pmarinus_7.0:GL481210:3001:5030:1 gene:ENSPMAG00000003685.1 transcript:ENSPMAT00000004027.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 2.121e-7
Identity = 47/173 (27.17%), Postives = 74/173 (42.77%), Query Frame = 1
Query:  172 CGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIF 690
            C   L     LV D+  +ASS F            + P  AR   D+  +  AW   +        +L+IDLG    I    T+G    G   +F   Y++    E+ + W +YK  D      ++  G  D         +PPI+ R+VR+ P+S+   R+ L+++L GC F
Sbjct:    2 CSEPLGLKSGLVGDTQISASSVF---QTLGLPCWTWEPHLAR--LDRQGRINAW---SAAKGDPNQWLQIDLGEARKITGIVTQGARDLGH-MQFVRSYRVA-SSEDGAAWTVYK--DDETRRDKIFAGNYDNNSHKKNMFNPPIIARYVRVLPYSW-YRRITLRVELIGCDF 161          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Sea Lamprey
Match: CPXM2 (carboxypeptidase X, M14 family member 2 [Source:HGNC Symbol;Acc:HGNC:26977])

HSP 1 Score: 48.1358 bits (113), Expect = 8.316e-6
Identity = 43/173 (24.86%), Postives = 76/173 (43.93%), Query Frame = 1
Query:  178 SKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFED 696
            S  +DDF +    A T S Y +   R        + +A   + + D  D AWC     AQ    ++E+D  R+T      T+GR +Q      +  YK+ +  +  S W  Y+    N     + +  +D        L+  +V R++RI P ++    +C++L++ GC  +D
Sbjct:   10 SMRIDDFQI---HASTISRYGLGAHRGR-----LNIQAG--MLEDDQYDGAWCAGRHDAQQ---WMEVDARRITNFTGVITQGRNSQQTHAWITS-YKVMFSNDSHS-WITYQ----NGADERLFEANHDQDTPVVNELEIAVVARYIRINPITWH-GDICMRLEVLGCPMKD 162          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Nematostella
Match: EDO46425 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ36])

HSP 1 Score: 66.6254 bits (161), Expect = 5.369e-13
Identity = 50/161 (31.06%), Postives = 74/161 (45.96%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCI 687
            + DSA TASSY         +     P   R      N    W      +QS  +Y++IDLGR+T +    T+G        E+   YKI Y   + S WKLY+      G  +V  G  D     Y  L  PIVTR +RI+  +++  R  L+++++GC+
Sbjct:    8 ISDSAITASSYH------NVESFQLPPSHGRL-----NHGSVWA---SASQSPGEYIQIDLGRVTTVTKVATQGNSNY---DEWMTSYKIGY-STDLSTWKLYREG----GQEKVFPGNTDGTTLVYGVLPQPIVTRGIRIFAETFQ-HRPALRMEIYGCM 145          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Nematostella
Match: EDO41138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S537])

HSP 1 Score: 66.2402 bits (160), Expect = 7.386e-13
Identity = 53/172 (30.81%), Postives = 79/172 (45.93%), Query Frame = 1
Query:  178 SKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGR--FAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCI 687
            S L  +   + DSA TASSY+              PK  R      N   AW      +QS  +Y ++DLGR+  +    T+G   FA     E+   YKI Y   + S WK+Y+      G  +V  G  D +   Y  L  P+VTR +RI   ++E  R  ++L+++GC+
Sbjct:    1 SALGMESGAISDSAITASSYW----------NSLPPKNGRL-----NNATAW---GSASQSPGEYFQVDLGRVITVTKVATQGNRNFA-----EWMTSYKIGYS-SDLSIWKVYREG----GQEKVFPGNTDRYTVVYGVLAQPVVTRGIRIIAVTFEW-RPVIRLEIYGCM 143          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Nematostella
Match: EDO46426 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ38])

HSP 1 Score: 63.929 bits (154), Expect = 4.444e-12
Identity = 47/165 (28.48%), Postives = 73/165 (44.24%), Query Frame = 1
Query:  193 DFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCI 687
            +   + DSA TASSY+   S      +   P   R      N +  W      +QS  +Y++IDLGR+T +    T+G        E+   YKI Y     S W++Y       G  +V  G  D     Y  L  PI TR +RI   ++ + R   +++++GC+
Sbjct:    4 ESGTINDSAITASSYYHAGS------LQLPPSHGRL-----NHESVWA---SASQSPGEYIQIDLGRVTTVTKVATQGNSNH---DEWMTSYKIGYSSYR-STWQIYHEG----GQEKVFPGKTDSNTIVYGVLAQPIATRGIRIIAVTF-VHRPAARVEIYGCM 145          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Nematostella
Match: EDO34668 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNS1])

HSP 1 Score: 56.9954 bits (136), Expect = 1.060e-9
Identity = 43/164 (26.22%), Postives = 78/164 (47.56%), Query Frame = 1
Query:  202 LVPDSAFTASSYFIPTSRTTEKMMDFSPKAAR--EIYDKDNQDYA-WCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGC 684
            ++PD+  TASSY+            + P+  R   +Y  D+ +   W  R  +   + +YL++D+GRL  +    T+GR  Q    ++   YKI Y   + SNW +Y++  ++    +V  G  D     Y  L  P+  R VR    S+    + ++++++GC
Sbjct:    1 MIPDACMTASSYYDN---------GYEPRNGRLKNVYVSDSVNRGMWSARRNL---VGEYLQVDVGRLVGVTKVATQGR--QWQFTQYVTSYKIGY-STDLSNWAIYRKGGID----KVFPGNTDTSSIVYNHLAAPLPARGVRFIAQSWA-DHISMRVEIYGC 144          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Nematostella
Match: EDO33236 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SST8])

HSP 1 Score: 56.9954 bits (136), Expect = 1.266e-9
Identity = 47/160 (29.38%), Postives = 79/160 (49.38%), Query Frame = 1
Query:  205 VPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGC 684
            +PDSA TASSYFI  +         +PK  R   ++D +  AWC +  VA    +YL++D+GR  ++    T+GR   G   ++   Y++ + R+  + W  Y  +D   G+ +V  G  D        L      R+VRI+  ++    + L+ +L+GC
Sbjct:   10 IPDSAMTASSYFIGDNYC-------APKEGRIHSERDTK--AWCAKQNVAG---EYLQVDIGREVLLTKIATQGR---GIYLQWVTSYELSHSRDGQA-WTPY--YD-EQGHAKVFPGNQDNSTVVSHPLPYHPRVRYVRIFAKTWH-RHISLRAELYGC 149          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Medaka
Match: ddr1 (epithelial discoidin domain-containing receptor 1 [Source:NCBI gene;Acc:101172605])

HSP 1 Score: 153.295 bits (386), Expect = 9.351e-38
Identity = 114/371 (30.73%), Postives = 174/371 (46.90%), Query Frame = 1
Query:  169 KCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISE 1266
            +C   L  +   +PDS  +ASS +   S +TE        A          D AWCP   V  S  +YL+IDL +L  +    T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  +      + L PPIV R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + L G+   VY    DS +DG+ +Q +   GLG+L D   GG+      E        YVGW+R  +G   + SV + F F+  R F + +++    HT  +    K+E  F L G      +  +     L  +   D  S  I   +  +  Q L  K YF   W+L+SEI F+SE
Sbjct:   34 QCRYALGMEAGTIPDSDISASSAW---SDSTE--------AKHGRLSTGEGDGAWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGV-KWITWK----DRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----TSPVGHVMNLPGL--PVY--LNDSIYDGSTEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALG---QGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSKVECLFKL-GILLPWSSPPLTLPVPL--EDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSE 373          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Medaka
Match: ddr1 (epithelial discoidin domain-containing receptor 1 [Source:NCBI gene;Acc:101172605])

HSP 1 Score: 153.295 bits (386), Expect = 9.351e-38
Identity = 114/371 (30.73%), Postives = 174/371 (46.90%), Query Frame = 1
Query:  169 KCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISE 1266
            +C   L  +   +PDS  +ASS +   S +TE        A          D AWCP   V  S  +YL+IDL +L  +    T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  +      + L PPIV R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + L G+   VY    DS +DG+ +Q +   GLG+L D   GG+      E        YVGW+R  +G   + SV + F F+  R F + +++    HT  +    K+E  F L G      +  +     L  +   D  S  I   +  +  Q L  K YF   W+L+SEI F+SE
Sbjct:   34 QCRYALGMEAGTIPDSDISASSAW---SDSTE--------AKHGRLSTGEGDGAWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGV-KWITWK----DRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----TSPVGHVMNLPGL--PVY--LNDSIYDGSTEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALG---QGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSKVECLFKL-GILLPWSSPPLTLPVPL--EDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSE 373          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Medaka
Match: ddr1 (epithelial discoidin domain-containing receptor 1 [Source:NCBI gene;Acc:101172605])

HSP 1 Score: 153.295 bits (386), Expect = 9.358e-38
Identity = 114/371 (30.73%), Postives = 174/371 (46.90%), Query Frame = 1
Query:  169 KCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISE 1266
            +C   L  +   +PDS  +ASS +   S +TE        A          D AWCP   V  S  +YL+IDL +L  +    T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  +      + L PPIV R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + L G+   VY    DS +DG+ +Q +   GLG+L D   GG+      E        YVGW+R  +G   + SV + F F+  R F + +++    HT  +    K+E  F L G      +  +     L  +   D  S  I   +  +  Q L  K YF   W+L+SEI F+SE
Sbjct:   34 QCRYALGMEAGTIPDSDISASSAW---SDSTE--------AKHGRLSTGEGDGAWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGV-KWITWK----DRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----TSPVGHVMNLPGL--PVY--LNDSIYDGSTEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALG---QGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSKVECLFKL-GILLPWSSPPLTLPVPL--EDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSE 373          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Medaka
Match: ddr1 (epithelial discoidin domain-containing receptor 1 [Source:NCBI gene;Acc:101172605])

HSP 1 Score: 152.91 bits (385), Expect = 1.157e-37
Identity = 114/371 (30.73%), Postives = 174/371 (46.90%), Query Frame = 1
Query:  169 KCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISE 1266
            +C   L  +   +PDS  +ASS +   S +TE        A          D AWCP   V  S  +YL+IDL +L  +    T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  +      + L PPIV R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + L G+   VY    DS +DG+ +Q +   GLG+L D   GG+      E        YVGW+R  +G   + SV + F F+  R F + +++    HT  +    K+E  F L G      +  +     L  +   D  S  I   +  +  Q L  K YF   W+L+SEI F+SE
Sbjct:   34 QCRYALGMEAGTIPDSDISASSAW---SDSTE--------AKHGRLSTGEGDGAWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGV-KWITWK----DRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----TSPVGHVMNLPGL--PVY--LNDSIYDGSTEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALG---QGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSKVECLFKL-GILLPWSSPPLTLPVPL--EDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSE 373          
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Medaka
Match: ddr1 (epithelial discoidin domain-containing receptor 1 [Source:NCBI gene;Acc:101172605])

HSP 1 Score: 150.214 bits (378), Expect = 4.786e-37
Identity = 113/370 (30.54%), Postives = 173/370 (46.76%), Query Frame = 1
Query:  169 KCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNE-----AMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            +C   L  +   +PDS  +ASS +   S +TE        A          D AWCP   V  S  +YL+IDL +L  +    T+GR A G G+EF+  Y+++Y R+    W  +K    +   +EV+ G  +      + L PPIV R VR YP +  +M VCL+++L+GC++ D +  Y     + P    + L G+   VY    DS +DG+ +Q +   GLG+L D   GG+      E        YVGW+R  +G   + SV + F F+  R F + +++    HT  +    K+E  F L G      +  +     L  +   D  S  I   +  +  Q L  K YF   W+L+SEI F+S
Sbjct:   24 QCRYALGMEAGTIPDSDISASSAW---SDSTE--------AKHGRLSTGEGDGAWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGV-KWITWK----DRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAY-----TSPVGHVMNLPGL--PVY--LNDSIYDGSTEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALG---QGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSKVECLFKL-GILLPWSSPPLTLPVPL--EDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLS 362          
BLAST of Discoidin domain-containing receptor 2 vs. Planmine SMEST
Match: SMESG000000860.1 (SMESG000000860.1)

HSP 1 Score: 1380.93 bits (3573), Expect = 0.000e+0
Identity = 685/686 (99.85%), Postives = 685/686 (99.85%), Query Frame = 1
Query:   97 MHLQILVLFSIYFKQIYSKIDSRSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLPLLEKSTKSISENSQSQVDSTLSIDAVYMXXXXXXXXXXXXXXXXVFWLIMRHRRIKRKKDMKKHELAFYSQNPFKTLNMSPYNQSGFHLISNAYISEYTAGMAPRGSISSKPEPCLFNPNLKNQNCMTLPKQSGQINESSIYTSIPGSDNDSSVGTDYMASNAVNNSHTYTQTIPLSGSIADFMLNQPQIIGNPLVELLDKQQYYGRPSNNALYSYEPDIVAMTNSPNHMNSTNSNSQSFTGSGIYQPIDYNSTIEKSFFSVPNKYRGSPMKLDPLLN 2154
            MHLQILVLFSIYFKQIYSKIDSRSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLPLLEKSTKSISENSQSQVDSTLSIDAVYMLTILLCLLLGIICAITVFWLIMRHRRIKRKKDMKKHELAFYSQNPFKTLNMSPYNQSGFHLISNAYISEYTAGMAPRGSISSKPEPCLFNPNLKNQNCMTLPKQSGQINESSIYTSIPGSDNDSSVGTDYMA NAVNNSHTYTQTIPLSGSIADFMLNQPQIIGNPLVELLDKQQYYGRPSNNALYSYEPDIVAMTNSPNHMNSTNSNSQSFTGSGIYQPIDYNSTIEKSFFSVPNKYRGSPMKLDPLLN
Sbjct:    1 MHLQILVLFSIYFKQIYSKIDSRSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLPLLEKSTKSISENSQSQVDSTLSIDAVYMLTILLCLLLGIICAITVFWLIMRHRRIKRKKDMKKHELAFYSQNPFKTLNMSPYNQSGFHLISNAYISEYTAGMAPRGSISSKPEPCLFNPNLKNQNCMTLPKQSGQINESSIYTSIPGSDNDSSVGTDYMAGNAVNNSHTYTQTIPLSGSIADFMLNQPQIIGNPLVELLDKQQYYGRPSNNALYSYEPDIVAMTNSPNHMNSTNSNSQSFTGSGIYQPIDYNSTIEKSFFSVPNKYRGSPMKLDPLLN 686          
BLAST of Discoidin domain-containing receptor 2 vs. Planmine SMEST
Match: SMESG000014159.1 (SMESG000014159.1)

HSP 1 Score: 281.182 bits (718), Expect = 5.843e-84
Identity = 197/524 (37.60%), Postives = 303/524 (57.82%), Query Frame = 1
Query:  286 KAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRRE--ETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIP--KNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS-ETAIGYDTKSEPILSTDLPLLEKSTKSISENSQSQVDSTLSIDAVYMXXXXXXXXXXXXXXXXVFWLIMRHRRIKRKKDMKKHELAFYSQNPFKTLNMSPYNQSGFHLISNAYISE--YTAGMAPRGSISSKPEPCLFNPNLKNQNCMTLPKQSGQIN-----ESSIYTSIPGSDNDSSVGTDYMASNAVNNS 1821
            K  +E YDK+N+ +AWCP N+V +SL +YL+IDLGRLT+I    T+GRFAQG+GKEF+P Y+I+Y R     S+WK Y++F    G++++L GP D F+DA+ETLDPPI+ R +RI+P+S  L RVCLKLQLFGCIF + ++EY+I +G+    K+  +++   +      F D+ +DGT     L+ GLG L DN+ G +F++   EA  Y+GW ++ + S   K + + F F + RNFSS   Y F   +L I+   +++  FS       Q++    E   LM + F+ S    I  ++  K G+++ L L+F S+W+LLSEI F+S        T   P +       +  T  I+E        T+SI+ +Y+LTILLCLLLGII AI  FW+I+R RR  +++ +KK  +A  SQ  F   N   +N      + ++  +   Y +    R +  ++    + +P+  N    T   Q+G ++     E++IYTSI  SDNDSS+  +Y   +  N++
Sbjct:    3 KFTKENYDKENEVFAWCPSNQVEKSLSEYLQIDLGRLTMIKVVLTKGRFAQGSGKEFTPLYQIRYSRNNGSGSDWKNYRKFKEK-GFQKILNGPTDAFIDAFETLDPPIIGRVIRIFPYSNVLQRVCLKLQLFGCIFSNDILEYQIPQGTAAFFKDDMIKIRNSFERNLEYFLDNGYDGTLFNDNLVGGLGLLTDNEIGLDFTVKETEAYRYIGWTQSPLKS---KPINIKFIFLNRRNFSSITFYSFSKPSLDINYFSRIDISFSS-----DQESLKTVEFDNLMRN-FNQSDHS-IKLDVGGKTGKFVNLTLHFASQWLLLSEIRFVSYHLNASQSTHITPSIIYRNFNYDSVTPKIAE-------KTVSIEIIYLLTILLCLLLGIITAICSFWIIIRKRRSNQRRSIKKQAMALCSQTSFIPYN---HNSKSVQCLPSSLATRPVYPSFTVDRRNYPNETFRKISHPSGSNLPPSTSLDQNGFMSKQYLPETNIYTSIGSSDNDSSLSPEYGTMSMTNDT 505          
BLAST of Discoidin domain-containing receptor 2 vs. Planmine SMEST
Match: SMESG000014159.1 (SMESG000014159.1)

HSP 1 Score: 280.026 bits (715), Expect = 2.209e-83
Identity = 196/523 (37.48%), Postives = 302/523 (57.74%), Query Frame = 1
Query:  289 AAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRRE--ETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIP--KNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS-ETAIGYDTKSEPILSTDLPLLEKSTKSISENSQSQVDSTLSIDAVYMXXXXXXXXXXXXXXXXVFWLIMRHRRIKRKKDMKKHELAFYSQNPFKTLNMSPYNQSGFHLISNAYISE--YTAGMAPRGSISSKPEPCLFNPNLKNQNCMTLPKQSGQIN-----ESSIYTSIPGSDNDSSVGTDYMASNAVNNS 1821
              +E YDK+N+ +AWCP N+V +SL +YL+IDLGRLT+I    T+GRFAQG+GKEF+P Y+I+Y R     S+WK Y++F    G++++L GP D F+DA+ETLDPPI+ R +RI+P+S  L RVCLKLQLFGCIF + ++EY+I +G+    K+  +++   +      F D+ +DGT     L+ GLG L DN+ G +F++   EA  Y+GW ++ + S   K + + F F + RNFSS   Y F   +L I+   +++  FS       Q++    E   LM + F+ S    I  ++  K G+++ L L+F S+W+LLSEI F+S        T   P +       +  T  I+E        T+SI+ +Y+LTILLCLLLGII AI  FW+I+R RR  +++ +KK  +A  SQ  F   N   +N      + ++  +   Y +    R +  ++    + +P+  N    T   Q+G ++     E++IYTSI  SDNDSS+  +Y   +  N++
Sbjct:   18 CRKENYDKENEVFAWCPSNQVEKSLSEYLQIDLGRLTMIKVVLTKGRFAQGSGKEFTPLYQIRYSRNNGSGSDWKNYRKFKEK-GFQKILNGPTDAFIDAFETLDPPIIGRVIRIFPYSNVLQRVCLKLQLFGCIFSNDILEYQIPQGTAAFFKDDMIKIRNSFERNLEYFLDNGYDGTLFNDNLVGGLGLLTDNEIGLDFTVKETEAYRYIGWTQSPLKS---KPINIKFIFLNRRNFSSITFYSFSKPSLDINYFSRIDISFSS-----DQESLKTVEFDNLMRN-FNQSDHS-IKLDVGGKTGKFVNLTLHFASQWLLLSEIRFVSYHLNASQSTHITPSIIYRNFNYDSVTPKIAE-------KTVSIEIIYLLTILLCLLLGIITAICSFWIIIRKRRSNQRRSIKKQAMALCSQTSFIPYN---HNSKSVQCLPSSLATRPVYPSFTVDRRNYPNETFRKISHPSGSNLPPSTSLDQNGFMSKQYLPETNIYTSIGSSDNDSSLSPEYGTMSMTNDT 519          
BLAST of Discoidin domain-containing receptor 2 vs. Planmine SMEST
Match: SMESG000014159.1 (SMESG000014159.1)

HSP 1 Score: 260.766 bits (665), Expect = 3.930e-76
Identity = 139/330 (42.12%), Postives = 209/330 (63.33%), Query Frame = 1
Query:  286 KAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRRE--ETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIP--KNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLGRLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFIS 1263
            K  +E YDK+N+ +AWCP N+V +SL +YL+IDLGRLT+I    T+GRFAQG+GKEF+P Y+I+Y R     S+WK Y++F    G++++L GP D F+DA+ETLDPPI+ R +RI+P+S  L RVCLKLQLFGCIF + ++EY+I +G+    K+  +++   +      F D+ +DGT     L+ GLG L DN+ G +F++   EA  Y+GW ++ + S   K + + F F + RNFSS   Y F   +L I+   +++  FS       Q++    E   LM + F+ S    I  ++  K G+++ L L+F S+W+LLSEI F+S
Sbjct:    3 KFTKENYDKENEVFAWCPSNQVEKSLSEYLQIDLGRLTMIKVVLTKGRFAQGSGKEFTPLYQIRYSRNNGSGSDWKNYRKFKEK-GFQKILNGPTDAFIDAFETLDPPIIGRVIRIFPYSNVLQRVCLKLQLFGCIFSNDILEYQIPQGTAAFFKDDMIKIRNSFERNLEYFLDNGYDGTLFNDNLVGGLGLLTDNEIGLDFTVKETEAYRYIGWTQSPLKS---KPINIKFIFLNRRNFSSITFYSFSKPSLDINYFSRIDISFSS-----DQESLKTVEFDNLMRN-FNQSDHS-IKLDVGGKTGKFVNLTLHFASQWLLLSEIRFVS 321          
BLAST of Discoidin domain-containing receptor 2 vs. Planmine SMEST
Match: SMESG000056781.1 (SMESG000056781.1)

HSP 1 Score: 227.254 bits (578), Expect = 4.521e-62
Identity = 187/594 (31.48%), Postives = 301/594 (50.67%), Query Frame = 1
Query:   91 LKMHLQILVLFSIYFKQIYSKIDSRSKCGSKLLDDFNLVPDSAFTASSYFIPTSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRLTVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYREVLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFEDHVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGT-NDQGLLINGLGRLIDNKTGGNFSLDP--NEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFSSAKLYI---FENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFSDSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSEPILSTDLPLLEKSTKSISENSQSQVDSTLSIDAVYMXXXXXXXXXXXXXXXXVFWLIMRHRRIKRKKDMKK----------------HELAFYSQNPFKTLNMSPYNQSGFHLISNAYISEYTAGMAPRGSISSKPEPCLFNPNLKNQNCMTLPKQSGQINESSIYTSIPGSDNDSSVGTDYMASN 1806
            L M L  L+  SI   ++ S   S  +C  KLL++ + VPDSA++ SSY            +F  +  R   D  N++ AWCP NKV +S+++++ +DLGRL+VI    TRGR A G G   +  Y I+Y++E  S WK YK +    G +E++    DP  + + +L+PP++TRW+R+YP+     ++CLKLQL+GCI  +HV+EYR+ +GS       + +G   A    F+D+++DGT    G LI G+G+L D     N + +P  + A  YVGW+RN++    +  VTL FRFDS RNFS+  + +   F+N  +++   + M   F  + D ++       +  ++ +D      S W    +    G ++++ LYF S+WI+LSEI F SE A   D +      TD+P+  K+   +++ +   ++   ++  +     L+C +LGII       L+  H R KR    K+                +E  FYS    K   + P+N S +   S    S+    + P       P+  + N N       + P  + +  +S IYTS+P SD + S+GT    SN
Sbjct:    2 LAMCLSGLLYISIVLIEVKSSPYS-PECNQKLLENRDNVPDSAYSESSY----------ENNFKGQYVR---DSSNEEQAWCPLNKVGKSMKEFVSVDLGRLSVIKMIMTRGRNAIGYGS--AQKYYIEYKQENQSEWKFYKNYS---GSQELI-ARKDPLNENFISLEPPLITRWLRVYPYLTANDKICLKLQLYGCINTNHVVEYRMIDGS-------KYAGFNSA---RFKDTTYDGTLMKNGTLIGGIGKLTDRDIESNTASNPIVDSATKYVGWDRNQL---KQAFVTLIFRFDSARNFSALSVRVANLFDNE-IRVFNMIVM--TFGWHSDGWNILRKTGTQKEKIENDD-RIRISRWKEIKINNFCGNFVKIDLYFASQWIILSEIYFHSEPAANIDEEFSNNFLTDIPINIKAPNQVNDQN---INFNFNVMPLAHTLGLICGILGIIILFGFCLLLYMHNRRKRNSPTKERVIQLKYPDDENFFLANENQFYSTKLNKG-TIIPFNISPYKYCSTQRSSK---NLPPHTQGLLTPKHNIVNVNSPKVIIKSSPIHNNRGIDSCIYTSLPASDTE-SLGTPDRKSN 550          
The following BLAST results are available for this feature:
BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DDR14.631e-3529.88discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
DDR14.631e-3529.88discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
DDR14.631e-3529.88discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
DDR14.631e-3529.88discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
DDR15.060e-3529.88discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ddr-21.323e-2729.08Discoidin domain-containing receptor tyrosine kina... [more]
ddr-25.118e-2730.00Discoidin domain-containing receptor tyrosine kina... [more]
ddr-25.118e-2730.00Discoidin domain-containing receptor tyrosine kina... [more]
ddr-17.094e-2527.02Discoidin domain-containing receptor A [Source:Un... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smal6.583e-4630.40gene:FBgn0085409 transcript:FBtr0329980[more]
smal6.583e-4630.40gene:FBgn0085409 transcript:FBtr0112617[more]
smal1.515e-4530.40gene:FBgn0085409 transcript:FBtr0329979[more]
Ddr2.768e-4329.01gene:FBgn0053531 transcript:FBtr0344771[more]
Ddr2.768e-4329.01gene:FBgn0053531 transcript:FBtr0344770[more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddr11.028e-4031.28discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
ddr11.028e-4031.28discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
ddr11.194e-4031.28discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
ddr11.429e-4031.28discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
ddr11.249e-3731.82discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DDR25.772e-3128.84discoidin domain receptor tyrosine kinase 2 [Sourc... [more]
DDR26.884e-3128.84discoidin domain receptor tyrosine kinase 2 [Sourc... [more]
DDR27.695e-3128.84discoidin domain receptor tyrosine kinase 2 [Sourc... [more]
ddr2l8.497e-3127.25discoidin domain receptor tyrosine kinase 2 like [... [more]
DDR26.237e-3028.81discoidin domain receptor tyrosine kinase 2 [Sourc... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ddr12.971e-3629.88discoidin domain receptor family, member 1 [Source... [more]
Ddr11.730e-3529.79discoidin domain receptor family, member 1 [Source... [more]
Ddr11.783e-3529.88discoidin domain receptor family, member 1 [Source... [more]
Ddr11.783e-3529.88discoidin domain receptor family, member 1 [Source... [more]
Ddr11.783e-3529.88discoidin domain receptor family, member 1 [Source... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q63474|DDR1_RAT4.116e-3530.49Epithelial discoidin domain-containing receptor 1 ... [more]
sp|Q03146|DDR1_MOUSE1.247e-3429.88Epithelial discoidin domain-containing receptor 1 ... [more]
sp|Q08345|DDR1_HUMAN3.010e-3429.88Epithelial discoidin domain-containing receptor 1 ... [more]
sp|Q7YR43|DDR1_PANTR4.431e-3430.15Epithelial discoidin domain-containing receptor 1 ... [more]
sp|Q16832|DDR2_HUMAN1.434e-3129.14Discoidin domain-containing receptor 2 OS=Homo sap... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2D7M29.071e-5533.25Discoidin domain-containing receptor 2 isoform 2 O... [more]
A0A4Z2D7P03.005e-5433.25Discoidin domain-containing receptor 2 isoform 1 O... [more]
A0A183QKB03.115e-5432.44F5/8 type C domain-containing protein OS=Schistoso... [more]
G4V7C29.067e-5432.21Putative discoidin domain receptor OS=Schistosoma ... [more]
A0A5K4FC051.471e-5332.21Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddr19.368e-3630.25discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
ddr11.010e-3530.25discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
ddr11.158e-3530.25discoidin domain receptor tyrosine kinase 1 [Sourc... [more]
ENSAMXT00000019857.22.332e-3130.27discoidin domain-containing receptor 2-like [Sourc... [more]
ddr2a8.615e-2730.06discoidin domain receptor tyrosine kinase 2 [Sourc... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000007840.19.408e-1131.07pep scaffold:Pmarinus_7.0:GL477602:191978:197608:1... [more]
ENSPMAT00000001939.12.199e-1025.18pep scaffold:Pmarinus_7.0:GL476444:333387:405756:1... [more]
ENSPMAT00000004027.12.121e-727.17pep scaffold:Pmarinus_7.0:GL481210:3001:5030:1 gen... [more]
CPXM28.316e-624.86carboxypeptidase X, M14 family member 2 [Source:HG... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO464255.369e-1331.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411387.386e-1330.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO464264.444e-1228.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO346681.060e-926.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO332361.266e-929.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddr19.351e-3830.73epithelial discoidin domain-containing receptor 1 ... [more]
ddr19.351e-3830.73epithelial discoidin domain-containing receptor 1 ... [more]
ddr19.358e-3830.73epithelial discoidin domain-containing receptor 1 ... [more]
ddr11.157e-3730.73epithelial discoidin domain-containing receptor 1 ... [more]
ddr14.786e-3730.54epithelial discoidin domain-containing receptor 1 ... [more]
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BLAST of Discoidin domain-containing receptor 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000000860.10.000e+099.85SMESG000000860.1[more]
SMESG000014159.15.843e-8437.60SMESG000014159.1[more]
SMESG000014159.12.209e-8337.48SMESG000014159.1[more]
SMESG000014159.13.930e-7642.12SMESG000014159.1[more]
SMESG000056781.14.521e-6231.48SMESG000056781.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016315 ID=SMED30016315|Name=Discoidin domain-containing receptor 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2488bp
TTTTTTTTTATCAGTTGATTTATTAATGCATTATTAGTGTAATGGAGATT
TAAAACCTGTGGTTATTTTTTTTTTCACATTTTAAGTACCTTGAAGATGC
ATCTACAAATTTTGGTTCTATTTTCAATATATTTCAAACAGATTTATTCA
AAAATTGATAGTAGAAGTAAATGTGGCTCAAAGTTACTCGATGATTTTAA
CTTGGTCCCCGATTCAGCCTTTACGGCTTCAAGTTATTTCATTCCAACTT
CTAGAACGACGGAGAAAATGATGGATTTCAGTCCAAAAGCGGCGCGAGAA
ATCTACGACAAAGACAACCAGGACTACGCCTGGTGTCCGAGAAATAAGGT
TGCACAATCTTTGGAAGATTATTTAGAAATTGATCTTGGTAGATTGACAG
TGATAAATTATGCACAGACCAGAGGCAGATTCGCTCAAGGGGCTGGTAAA
GAATTCAGTCCATTTTATAAAATACAATATCGGCGAGAAGAAACCAGCAA
TTGGAAGTTGTATAAGAGATTTGATGTTAATCTGGGATATCGAGAAGTGC
TCAAAGGACCAAATGATCCGTTTCTAGATGCTTATGAAACATTAGATCCT
CCTATCGTTACCAGATGGGTTAGGATTTACCCGTTCAGTTATGAACTCAT
GAGAGTTTGTTTGAAACTTCAATTATTTGGATGCATATTTGAAGATCATG
TAATGGAATATCGAATCCATGAAGGAAGTATTCCGAAGAATTCATTTTTG
CAGTTGTCTGGAATTTATCCAGCTGTATACAATGTGTTTCAAGATTCGAG
TTTCGATGGAACAAATGATCAAGGCTTATTAATTAATGGACTTGGTAGAT
TAATTGACAATAAAACCGGTGGAAATTTTTCACTTGATCCAAATGAAGCA
ATGCATTATGTTGGATGGAACCGGAATGAAATTGGAAGCTCAAATGAAAA
ATCCGTTACATTATGGTTTCGATTTGATTCTGTGAGAAATTTCAGTTCAG
CTAAGTTATACATCTTTGAAAATCACACACTAAAGATAAGCCAACCTGTA
AAAATGGAAGCAAAATTTAGTTTATATGGCGATAAATTCAGTCAGAAAAA
TACTATAATAGCTGAAAACCCAGAATTAATGTCAGACAGCTTTTCAGATT
CCAAATCTCCGTGGATTTATTTCAATATGCAGGAGAAAATCGGTCAATAT
TTACAATTGAAACTGTATTTCAAATCAGAATGGATTCTTCTCAGTGAAAT
AGATTTCATCAGCGAGACTGCCATTGGTTATGATACGAAATCTGAACCAA
TTCTATCAACTGATTTGCCATTGTTAGAAAAATCTACGAAATCAATATCA
GAAAATTCCCAAAGCCAAGTCGACTCTACCCTTTCAATAGATGCAGTCTA
TATGTTAACAATATTACTTTGTTTGTTGCTAGGGATCATTTGTGCAATTA
CTGTATTCTGGCTCATTATGAGACATCGACGAATTAAGAGAAAAAAAGAC
ATGAAGAAACATGAACTTGCATTTTATTCACAAAACCCTTTCAAAACTCT
CAACATGTCACCTTACAATCAATCCGGATTTCATTTGATATCTAATGCTT
ATATTAGTGAATACACTGCAGGGATGGCCCCTAGAGGCTCAATTAGTAGC
AAACCAGAGCCGTGTTTATTCAATCCCAACCTGAAAAATCAAAACTGTAT
GACACTGCCTAAACAAAGTGGGCAAATAAACGAAAGCAGTATTTACACAA
GTATCCCCGGTTCTGACAATGATAGCTCAGTTGGAACCGACTATATGGCA
AGTAATGCCGTAAATAATTCACACACGTACACACAAACTATTCCTCTATC
AGGATCTATAGCAGACTTTATGCTAAATCAGCCTCAGATTATTGGAAATC
CATTAGTAGAATTATTAGACAAGCAGCAATATTATGGAAGACCTTCAAAT
AATGCTCTTTATTCTTATGAACCGGATATAGTAGCCATGACAAATAGCCC
AAATCACATGAATTCAACAAATAGCAACTCCCAGTCTTTCACAGGATCTG
GCATTTATCAGCCAATAGATTATAACAGTACAATTGAAAAATCCTTCTTT
TCCGTTCCCAACAAATATCGTGGCTCACCGATGAAACTGGATCCATTGCT
TAACTGAAACTTTTTATCAAAATTCCTCCCCTTCACAAATCGAATGTTTC
TCTACTTTGAAAATTTCCGTAAATCTTATTGTATTTATTACAGTGATATA
GATAGCCGAAGCATCTGTGAGAAAAATTGAGAATGTATATAAATTTTGCA
AAAGTAAAACATTTACCAATCATATCATATGCCAATGAATGAGGCTATCC
CAAATCTTTGGATTTCACTTCTCTATGAAATCCGATTGTCACAGAAGAAT
CTTGATCGGTTACGATAATTTTCACTTACGCAGATCCAGAATTGTAAAAA
TTTGTTTATTTTATAATAAATTTTCTGTATTTCTTCAA
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protein sequence of SMED30016315-orf-1

>SMED30016315-orf-1 ID=SMED30016315-orf-1|Name=SMED30016315-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=687bp
MHLQILVLFSIYFKQIYSKIDSRSKCGSKLLDDFNLVPDSAFTASSYFIP
TSRTTEKMMDFSPKAAREIYDKDNQDYAWCPRNKVAQSLEDYLEIDLGRL
TVINYAQTRGRFAQGAGKEFSPFYKIQYRREETSNWKLYKRFDVNLGYRE
VLKGPNDPFLDAYETLDPPIVTRWVRIYPFSYELMRVCLKLQLFGCIFED
HVMEYRIHEGSIPKNSFLQLSGIYPAVYNVFQDSSFDGTNDQGLLINGLG
RLIDNKTGGNFSLDPNEAMHYVGWNRNEIGSSNEKSVTLWFRFDSVRNFS
SAKLYIFENHTLKISQPVKMEAKFSLYGDKFSQKNTIIAENPELMSDSFS
DSKSPWIYFNMQEKIGQYLQLKLYFKSEWILLSEIDFISETAIGYDTKSE
PILSTDLPLLEKSTKSISENSQSQVDSTLSIDAVYMLTILLCLLLGIICA
ITVFWLIMRHRRIKRKKDMKKHELAFYSQNPFKTLNMSPYNQSGFHLISN
AYISEYTAGMAPRGSISSKPEPCLFNPNLKNQNCMTLPKQSGQINESSIY
TSIPGSDNDSSVGTDYMASNAVNNSHTYTQTIPLSGSIADFMLNQPQIIG
NPLVELLDKQQYYGRPSNNALYSYEPDIVAMTNSPNHMNSTNSNSQSFTG
SGIYQPIDYNSTIEKSFFSVPNKYRGSPMKLDPLLN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0003104enteric muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000421FA58C
IPR008979Galactose-bd-like_sf
Vocabulary: cellular component
TermDefinition
GO:0005887integral component of plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0038062protein tyrosine kinase collagen receptor activity
Vocabulary: biological process
TermDefinition
GO:0038063collagen-activated tyrosine kinase receptor signaling pathway
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000421Coagulation factor 5/8 C-terminal domainSMARTSM00231disc_4coord: 6..177
e-value: 5.0E-7
score: 39.3
IPR000421Coagulation factor 5/8 C-terminal domainPFAMPF00754F5_F8_type_Ccoord: 46..162
e-value: 5.2E-12
score: 46.0
IPR000421Coagulation factor 5/8 C-terminal domainPROSITEPS50022FA58C_3coord: 7..177
score: 22.128
NoneNo IPR availableGENE3DG3DSA:2.60.120.1190coord: 182..379
e-value: 5.6E-37
score: 129.1
NoneNo IPR availablePANTHERPTHR24416:SF515coord: 54..471
NoneNo IPR availablePANTHERPTHR24416TYROSINE-PROTEIN KINASE RECEPTORcoord: 54..471
NoneNo IPR availableTMHMMTMhelixcoord: 416..438
IPR008979Galactose-binding-like domain superfamilyGENE3DG3DSA:2.60.120.260coord: 3..181
e-value: 2.7E-28
score: 100.8
IPR008979Galactose-binding-like domain superfamilySUPERFAMILYSSF49785Galactose-binding domain-likecoord: 15..177