Dynamin-type G domain-containing protein
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30016209 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]) HSP 1 Score: 328.946 bits (842), Expect = 8.742e-101 Identity = 219/691 (31.69%), Postives = 367/691 (53.11%), Query Frame = 2
Query: 242 EKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCN--TIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQL-------------------NVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGH T+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + ++QH +RC+ FL +EL+V EA RIFFVSAKE+L R + + L R + F FE+ E+ + SA+KTKF H+++ +++ + NI+ +N + + +V+++ + D I+N + + ++ K+I V + + K + ++ EI L+ +V F S F P+P + IYK+ELN H+E M +A+ C + ++ ++ +I+ LL I + +I + DL+ N + S+F+ED+ F++ L S+ + L A+ + + + L R L +M + ++ ++ +G + +I K G+++++ SL YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S +KQ + + +D + + EI + EI L I ++ ++++ L F +++L
Sbjct: 62 DKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIP-CKKFDLSYNLNYHKLCSDFQEDIVFRFSLGWSSLV-HRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNASQEELMITLVTGLASV-TSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAKERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFL 734
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]) HSP 1 Score: 328.946 bits (842), Expect = 8.742e-101 Identity = 219/691 (31.69%), Postives = 367/691 (53.11%), Query Frame = 2
Query: 242 EKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCN--TIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQL-------------------NVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGH T+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + ++QH +RC+ FL +EL+V EA RIFFVSAKE+L R + + L R + F FE+ E+ + SA+KTKF H+++ +++ + NI+ +N + + +V+++ + D I+N + + ++ K+I V + + K + ++ EI L+ +V F S F P+P + IYK+ELN H+E M +A+ C + ++ ++ +I+ LL I + +I + DL+ N + S+F+ED+ F++ L S+ + L A+ + + + L R L +M + ++ ++ +G + +I K G+++++ SL YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S +KQ + + +D + + EI + EI L I ++ ++++ L F +++L
Sbjct: 62 DKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIP-CKKFDLSYNLNYHKLCSDFQEDIVFRFSLGWSSLV-HRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNASQEELMITLVTGLASV-TSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAKERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFL 734
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]) HSP 1 Score: 328.946 bits (842), Expect = 1.020e-100 Identity = 213/630 (33.81%), Postives = 339/630 (53.81%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-----RYENFLQFERSLEKNLCASALKTKFASHSLQG---LELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSF-KNIFVNKEFV----------------GFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
K I +L R+ MK AFFGRTSNGKS+VIN+ML K+LP GIGHTT+CF++++GT F+ + +G++ + +V L+HAL DK + + SL+ + WP+ C LLK ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK FFHKV +LS+PNIFILNNRW + + + + ++QH +RC FL EL V +A +RIFFVSAKE+L R + L R F FER E+ + SA+KTKF H+++ E V ++++ LH + Q+ +++ DK ++ +KQI+ + + + + ++ EI+ L+ +V ++ F P P + +YK EL+ H+E+ + +++ C+ AI + ++ +ID LL + RS ID++ L + C+ + ++F+ED+ F + L ++ N L +R ++ +D VQ L P + + +EF+ G + ++ K G+R+I S YGLLY+YER+ W+ +E+ FK Q+V++AS +L VI N S ++Q+L
Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFL--------------LTEGSE-EKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQIT---EEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMIDGLKPLLPVSV-RSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLG-WTMLVNRFLGPKNSRRALMGYNDQVQR-PIPLTPANPSMPPLPQGSLTQEEFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]) HSP 1 Score: 328.946 bits (842), Expect = 1.020e-100 Identity = 213/630 (33.81%), Postives = 339/630 (53.81%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-----RYENFLQFERSLEKNLCASALKTKFASHSLQG---LELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSF-KNIFVNKEFV----------------GFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
K I +L R+ MK AFFGRTSNGKS+VIN+ML K+LP GIGHTT+CF++++GT F+ + +G++ + +V L+HAL DK + + SL+ + WP+ C LLK ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK FFHKV +LS+PNIFILNNRW + + + + ++QH +RC FL EL V +A +RIFFVSAKE+L R + L R F FER E+ + SA+KTKF H+++ E V ++++ LH + Q+ +++ DK ++ +KQI+ + + + + ++ EI+ L+ +V ++ F P P + +YK EL+ H+E+ + +++ C+ AI + ++ +ID LL + RS ID++ L + C+ + ++F+ED+ F + L ++ N L +R ++ +D VQ L P + + +EF+ G + ++ K G+R+I S YGLLY+YER+ W+ +E+ FK Q+V++AS +L VI N S ++Q+L
Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFL--------------LTEGSE-EKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQIT---EEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMIDGLKPLLPVSV-RSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLG-WTMLVNRFLGPKNSRRALMGYNDQVQR-PIPLTPANPSMPPLPQGSLTQEEFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]) HSP 1 Score: 249.595 bits (636), Expect = 3.139e-75 Identity = 136/318 (42.77%), Postives = 194/318 (61.01%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXX-XXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLN 1159
+ +K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGH T+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRWDA E + + ++QH +RC+ FL +EL+V EA RIFFVSAKE+L R + + L R + F FE+ E+ + SA+KTKF H+++ +++ + NI+ +N
Sbjct: 57 MQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVN 359
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Match: fzo-1 (Transmembrane GTPase fzo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q23424]) HSP 1 Score: 292.738 bits (748), Expect = 2.223e-87 Identity = 215/765 (28.10%), Postives = 368/765 (48.10%), Query Frame = 2
Query: 71 NNSDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTD-----KVSSESLILLYWPHQN----CELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTS-----ENSYRSNNPKVLDRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLN-VAVDKKLKESHIRDKIKNGNSKVNDNIV----------KQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCN--TIFSNFKEDLSFQWPLNPHSVFSNALL-----------------LSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+N L F+EAK + + + L + K + E D ++ E ++ I + + + I+ +R MK FFGRTSNGKS+ IN+ML +K+LP G+GHTT CF+Q++G+ ++ + ++DD Q + + + + HALS + + +SL+ ++ P ++ C LL+ +V LDSPGVD+ P+ D WI+ +CLDADVFVLV+NAESTLTQ EK FF +V KLSKPN+FILNNRWDA E + + KKQH R FL EL+VC+ E +RIFFVS++E+LE R + +Y++ R F FER E + SA+ TKF +H+ + H++ +++LNLN V + S +++ + N+ V +Q + + +K + EI L+ I+ F PFD + M YK +L V+K +++ + C G + I + + TK+L + +V + +I + + ++F EDL F++ H++ + LS + ++ N+ D S + M + F+ +G + ++ K G+RVI +Y LY +ER+RW+ +E++ K Q+ + + ++ V T + +++ + + G N++ +++I + +++ + G + + RNL +F YL
Sbjct: 33 DNEPLLRFREAKKVLGDVYGELKDNVAELEGVYKDIKENDFVSS---EQREEIEAIGDSIKTIMDTFQRDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSE-------------GEVGHLQLDDNPQ--KIDMKMLGKIGHALSDENSDLPAMGQDSLLKVFHPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDELEVCSEREVNDRIFFVSSREVLESRLKARGLVQKAYQAEGHGT--RALEFQNFERHFEHCISRSAIHTKFEAHNRRA-----------HEMIGKMRLNLNSVLTSAAEQRSKLQNNLNESTRTFNECRVNFTQFEKAYREQTEQLRAEVHLKVSADFFEEIARLDAIIDRFEQPFDGSSSGMTKYKEDLAIFVDKCLSSDLEARCTGGLMSRIWNLENDMFQYVTKILAEPYQNKLEEVWRYRAPFKFSICVDVPALVNDFHEDLEFRFTFGLHAIIRRIIAYRSGQPVTAINTNLLTPLSLKQQSEKNSVRDAEASAASEEQAMMTQMVLTSAAFLANGSLGVLVVGGIVYKAVGWRVIAVGGAAYAGLYAWERMRWNSGAKEQHLKEQFRSHLAARMQQVSTAHTHHCETQAIREMDQVFDGLKATVGGVHREMKNDLDVQKTQIDAVDSTIRTLGTIKGKAVFLLRNLEQFASSYL 766
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070910) HSP 1 Score: 348.206 bits (892), Expect = 1.029e-107 Identity = 229/675 (33.93%), Postives = 373/675 (55.26%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-------RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNS---KVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYE-IDRSMIDVIERTSEHDL--TIPCNTIFSNFKEDLSFQ--WPLNP----------------------------HSVFSNALLLSYEARNSMNNPDDNVQSLR-RQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEI 2134
K I +L+R MK AFFGRTSNGKSSVIN+ML +KILP GIGHTT+CF Q++G++ ++ M +G++ + L + ++ L++AL +K+ SL+ ++WP + C LL+ +V F+DSPGVD+ +LD WI+++CL+ADVFVLV NAEST+T+ EK FFH V KLSKPNIFILNNRWDA +E + + K QH +RCIDFLTKEL+V +EA ER+FFVSA+E L+ R E + N P + RY F FER E+ + SA+KTKF HS +G + M ++L + ++I + N+ D+K + + ++I+ + +V + +I +++ + K +++L EI L ++ F PF P+ ++IYK ELN HVE + + + + A+ + + + D+ L+ E + + ++ RT ++ ++ C + ++F+EDL F+ W + HSV S EA P V + QL+++ F S ++ VG ++ ++ K G+RV+ YG +YLYER+ W+ S +E+ FK+QYV++A+ +L ++D+ + N S ++Q+L + +D ++E++ +S++
Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYL--------------MTEGSE-EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEE--AKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVSGDMKSMLDNIYERITIFRNLKQDQK---NLLTERIQGTETQMMQVTREMKMKIHNMVEEVEEKVSKALNEEIWRLGVLIDEFNMPFHPERLVLNIYKKELNAHVESGLGSNLRARLSMALAMNVESAQTEMTDRMHALVPNEQLLATSTKMVVRTQPFEMLYSLNCQNLCADFQEDLEFKFSWGIAAMIQRFTGKVRERSKKGQPALVNRQSSIGHSV-STPTTTPVEATPVCLLPAPVVAGITPEQLSLISRFAVSS---IGSQGTVGGLVVAGVMLKTIGWRVLVGVGALYGCIYLYERLSWTNSAKERTFKSQYVRHATKKLKMIVDLTSANCSHQVQQELSSTFARLCRTVDTATTDMNDELKTLDSQL 775
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070909) HSP 1 Score: 348.206 bits (892), Expect = 1.029e-107 Identity = 229/675 (33.93%), Postives = 373/675 (55.26%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-------RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNS---KVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYE-IDRSMIDVIERTSEHDL--TIPCNTIFSNFKEDLSFQ--WPLNP----------------------------HSVFSNALLLSYEARNSMNNPDDNVQSLR-RQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEI 2134
K I +L+R MK AFFGRTSNGKSSVIN+ML +KILP GIGHTT+CF Q++G++ ++ M +G++ + L + ++ L++AL +K+ SL+ ++WP + C LL+ +V F+DSPGVD+ +LD WI+++CL+ADVFVLV NAEST+T+ EK FFH V KLSKPNIFILNNRWDA +E + + K QH +RCIDFLTKEL+V +EA ER+FFVSA+E L+ R E + N P + RY F FER E+ + SA+KTKF HS +G + M ++L + ++I + N+ D+K + + ++I+ + +V + +I +++ + K +++L EI L ++ F PF P+ ++IYK ELN HVE + + + + A+ + + + D+ L+ E + + ++ RT ++ ++ C + ++F+EDL F+ W + HSV S EA P V + QL+++ F S ++ VG ++ ++ K G+RV+ YG +YLYER+ W+ S +E+ FK+QYV++A+ +L ++D+ + N S ++Q+L + +D ++E++ +S++
Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYL--------------MTEGSE-EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEE--AKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVSGDMKSMLDNIYERITIFRNLKQDQK---NLLTERIQGTETQMMQVTREMKMKIHNMVEEVEEKVSKALNEEIWRLGVLIDEFNMPFHPERLVLNIYKKELNAHVESGLGSNLRARLSMALAMNVESAQTEMTDRMHALVPNEQLLATSTKMVVRTQPFEMLYSLNCQNLCADFQEDLEFKFSWGIAAMIQRFTGKVRERSKKGQPALVNRQSSIGHSV-STPTTTPVEATPVCLLPAPVVAGITPEQLSLISRFAVSS---IGSQGTVGGLVVAGVMLKTIGWRVLVGVGALYGCIYLYERLSWTNSAKERTFKSQYVRHATKKLKMIVDLTSANCSHQVQQELSSTFARLCRTVDTATTDMNDELKTLDSQL 775
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0343373) HSP 1 Score: 347.051 bits (889), Expect = 2.894e-107 Identity = 229/679 (33.73%), Postives = 372/679 (54.79%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXX-----XXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-------RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNS---KVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYE-IDRSMIDVIERTSEHDL--TIPCNTIFSNFKEDLSFQ--WPLNP----------------------------HSVFSNALLLSYEARNSMNNPDDNVQSLR-RQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEI 2134
K I +L+R MK AFFGRTSNGKSSVIN+ML +KILP GIGHTT+CF Q++G++ ++ M +G++ + L + ++ L++AL +K+ SL+ ++WP + C LL+ +V F+DSPGVD+ +LD WI+++CL+ADVFVLV NAEST+T+ EK FFH V KLSKPNIFILNNRWDA E ++ K QH +RCIDFLTKEL+V +EA ER+FFVSA+E L+ R E + N P + RY F FER E+ + SA+KTKF HS +G + M ++L + ++I + N+ D+K + + ++I+ + +V + +I +++ + K +++L EI L ++ F PF P+ ++IYK ELN HVE + + + + A+ + + + D+ L+ E + + ++ RT ++ ++ C + ++F+EDL F+ W + HSV S EA P V + QL+++ F S ++ VG ++ ++ K G+RV+ YG +YLYER+ W+ S +E+ FK+QYV++A+ +L ++D+ + N S ++Q+L + +D ++E++ +S++
Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYL--------------MTEGSE-EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEE--AKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVSGDMKSMLDNIYERITIFRNLKQDQK---NLLTERIQGTETQMMQVTREMKMKIHNMVEEVEEKVSKALNEEIWRLGVLIDEFNMPFHPERLVLNIYKKELNAHVESGLGSNLRARLSMALAMNVESAQTEMTDRMHALVPNEQLLATSTKMVVRTQPFEMLYSLNCQNLCADFQEDLEFKFSWGIAAMIQRFTGKVRERSKKGQPALVNRQSSIGHSV-STPTTTPVEATPVCLLPAPVVAGITPEQLSLISRFAVSS---IGSQGTVGGLVVAGVMLKTIGWRVLVGVGALYGCIYLYERLSWTNSAKERTFKSQYVRHATKKLKMIVDLTSANCSHQVQQELSSTFARLCRTVDTATTDMNDELKTLDSQL 779
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: fzo (gene:FBgn0011596 transcript:FBtr0084399) HSP 1 Score: 244.588 bits (623), Expect = 5.519e-70 Identity = 181/630 (28.73%), Postives = 316/630 (50.16%), Query Frame = 2
Query: 239 NEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQ--GTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW--XXXXXXXXXXXXKKQHQQRCIDFLTKELQV-CTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLDRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIV------KQISIVLDNIIMKTTESLRV----EIKHL-NYIVKNFTSPFDPD-PAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLR---RQLNVMRPFLNS-----FKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
+ + E I +L R +MK AFFGRTSNGKS+VIN++L +KILP +GHTTSCF Q+Q G+++T V+ ++ +++ + ++ L+ A S + +L+ + C +L +V +D+PGVD+ LD ++ C+DADVF+LV NAEST+++ E+ FF V +KLS+PN+FILNNRW + + + K QH +RC++ L EL V T +EA ERI+ VSA E L R + + S + RY+ FL+FE L SALKTKF H L + IL++L + V + + E+ +++ N N+++ D ++ + + + + T R +IK L V +F+ PF P+ PA + Y+ L H++K + +R+ + ++ +I+ +K EI + + E + + L + C + S+F+ DL F++ L AL E ++ +Q L+ ++ + + P +N +++ +K +G +SA+ + + ++ G Y+YE W+ + QE++FK+QY + +L + + + ++Q L
Sbjct: 72 SSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQED----------------EHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIRNGQITNPSGQTQ--QRYQEFLRFENDFSNCLAVSALKTKFGPHLLSAQK-------ILNQLKSTLICPFIEKVSRLIDEN--KERRANLNAEIEDWLILMQEDREALQYCFEELTEMTQRVGRCVLNDQIKTLIPSSVLSFSQPFHPEFPAQIGQYQRSLCAHLDKLLEDRVLQCLSIPLQRKILDIEK------------EIG---LPIAENSCDWQLIYGLDCQSYMSDFQPDLRFRFSLG-----FTALWHRLEGNLPLHASPFRIQKLQNGHKKCSPLPPLVNGNHWQMLESLVKSKGSLGTVLLSAMAIRSFNWPIVLILGGLVGSFYIYEYAAWTTAAQERSFKSQYARLLQQRLRSDVQQTVSGFELQLRQHL 654
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 338.191 bits (866), Expect = 1.555e-104 Identity = 225/698 (32.23%), Postives = 372/698 (53.30%), Query Frame = 2
Query: 221 DMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLDRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVI-ERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQ-------------------------SLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
D I S K I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT + F+ KT +G++ + I +V L+HAL D+ + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV KLSKPNIFILNNRWDA E + + +KQH RC++FL +EL+V +A RIFFVSAKE+L R + DR + F FERS E+ + SA+KTKF H+++ ++ E + +I+ ++N V+++++ D ++N + + +I K+I + + + K + ++ EI L+ I+ F S F P P + +YK++L +H+E+ M +A C+ A+ + ++ +I+ LL + +I R E + C T+ S+F+E++ FQ+ L S + L A+ ++ D N+Q + Q +M +N+ ++ ++ + + ++ + G+R+I S+ YGLLYLYER+ W+ +E+ K Q+V YA+ +L +I + N S ++Q++ + +D +++I++ +I L + + ++ L +F +YL
Sbjct: 56 DEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFL-----KT---------EGSE-EEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGGALAEGFQDRLKEFQNFERSFEECISHSAVKTKFEQHTIRAKQITETVKDIMDQINITAAEKRVVSLEEREYLIDRLDFVRNQLNLLIQDIKKKIKAITEEVENKVSNAMAEEICRLSVIIDEFRSDFHPSPQMLKMYKSDLLSHIEQGMGKNLAFRCSDAVNASVQCSQQDMIECLKPLLPSAAQTQLHMLIPSRKFELSYDLNCATLCSDFQENIEFQFSLG-WSALVHRFLGPVNAKRALMLVDQNLQLTAPTTPTAPAVVQSQNSRALGQNQASVTQEELMLTMVNNLASV-TSRTSMSVIIVGGVVWRTVGWRLIALSMSMYGLLYLYERLTWTTKAKERALKKQFVDYATEKLQMIISFTSSNCSHQVQQEIASTFARLCQQVDITQRDLESDIQRLTDKIQKLETVQNRSKVLRHKATALEMQLEDFSSQYL 736
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 335.88 bits (860), Expect = 1.441e-103 Identity = 226/703 (32.15%), Postives = 372/703 (52.92%), Query Frame = 2
Query: 221 DMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVI-ERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQ-------------------------SLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
D I S K I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT + F+ KT +G++ + I +V L+HAL D+ + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV KLSKPNIFILNNRWDA E + + +KQH RC++FL +EL+V +A RIFFVSAKE+L R L DR + F FERS E+ + SA+KTKF H+++ ++ E + +I+ ++N V+++++ D ++N + + +I K+I + + + K + ++ EI L+ I+ F S F P P + +YK++L +H+E+ M +A C+ A+ + ++ +I+ LL + +I R E + C T+ S+F+E++ FQ+ L S + L A+ ++ D N+Q + Q +M +N+ ++ ++ + + ++ + G+R+I S+ YGLLYLYER+ W+ +E+ K Q+V YA+ +L +I + N S ++Q++ + +D +++I++ +I L + + ++ L +F +YL
Sbjct: 56 DEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFL-----KT---------EGSE-EEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQNFERSFEECISHSAVKTKFEQHTIRAKQITETVKDIMDQINITAAEKRVVSLEEREYLIDRLDFVRNQLNLLIQDIKKKIKAITEEVENKVSNAMAEEICRLSVIIDEFRSDFHPSPQMLKMYKSDLLSHIEQGMGKNLAFRCSDAVNASVQCSQQDMIECLKPLLPSAAQTQLHMLIPSRKFELSYDLNCATLCSDFQENIEFQFSLG-WSALVHRFLGPVNAKRALMLVDQNLQLTAPTTPTAPAVVQSQNSRALGQNQASVTQEELMLTMVNNLASV-TSRTSMSVIIVGGVVWRTVGWRLIALSMSMYGLLYLYERLTWTTKAKERALKKQFVDYATEKLQMIISFTSSNCSHQVQQEIASTFARLCQQVDITQRDLESDIQRLTDKIQKLETVQNRSKVLRHKATALEMQLEDFSSQYL 741
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 335.88 bits (860), Expect = 1.441e-103 Identity = 226/703 (32.15%), Postives = 372/703 (52.92%), Query Frame = 2
Query: 221 DMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVI-ERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQ-------------------------SLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
D I S K I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT + F+ KT +G++ + I +V L+HAL D+ + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV KLSKPNIFILNNRWDA E + + +KQH RC++FL +EL+V +A RIFFVSAKE+L R L DR + F FERS E+ + SA+KTKF H+++ ++ E + +I+ ++N V+++++ D ++N + + +I K+I + + + K + ++ EI L+ I+ F S F P P + +YK++L +H+E+ M +A C+ A+ + ++ +I+ LL + +I R E + C T+ S+F+E++ FQ+ L S + L A+ ++ D N+Q + Q +M +N+ ++ ++ + + ++ + G+R+I S+ YGLLYLYER+ W+ +E+ K Q+V YA+ +L +I + N S ++Q++ + +D +++I++ +I L + + ++ L +F +YL
Sbjct: 56 DEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFL-----KT---------EGSE-EEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQNFERSFEECISHSAVKTKFEQHTIRAKQITETVKDIMDQINITAAEKRVVSLEEREYLIDRLDFVRNQLNLLIQDIKKKIKAITEEVENKVSNAMAEEICRLSVIIDEFRSDFHPSPQMLKMYKSDLLSHIEQGMGKNLAFRCSDAVNASVQCSQQDMIECLKPLLPSAAQTQLHMLIPSRKFELSYDLNCATLCSDFQENIEFQFSLG-WSALVHRFLGPVNAKRALMLVDQNLQLTAPTTPTAPAVVQSQNSRALGQNQASVTQEELMLTMVNNLASV-TSRTSMSVIIVGGVVWRTVGWRLIALSMSMYGLLYLYERLTWTTKAKERALKKQFVDYATEKLQMIISFTSSNCSHQVQQEIASTFARLCQQVDITQRDLESDIQRLTDKIQKLETVQNRSKVLRHKATALEMQLEDFSSQYL 741
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]) HSP 1 Score: 326.635 bits (836), Expect = 5.522e-100 Identity = 230/729 (31.55%), Postives = 368/729 (50.48%), Query Frame = 2
Query: 59 MTDKNNSDLASFKEAKNLSIANFKSISK-LNESLVNLNKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXX-XXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTS---EHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV-----------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKS 2161
M + N S L F AK F+ + + ES L ++ + + + E + K I +L R+ MK FFGRTSNGKSSVIN+ML K+LP GIGHTT+CF++++GT F++ + SD + + +V L+HAL D+ + + SL+ + WP C LL+ ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK+FFHKV +LS PNIFILNNRWDA + + + ++QH RC FL EL+V A +RIFFVSAKE+L+ R + L R F FER E+ + SA+KTKF H+ + ++ E + I+ ++ Q ++ K + + I + + +I + + + + + ++ EI+ L +V +F F P P + +YK EL+ H+E+ + ++ C+ AI + + +ID LL I + ++ R +DL C+ + S+F+ED+ F + L ++ N L R ++ +D V Q Q +M + ++ ++ +G + +I K G+R+I S+ YGLLY+YER+ W+ +E+ FK Q+V YAS +L ++ N S ++Q+L + +D + ++EI S+I L D L+S
Sbjct: 21 MAEVNASPLKHFVTAKKKINGIFEQLGAYIKESSAFLEETYSNEELDPVTTEEQVAEVRGYLSKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNESFLL---TEGSD------------ERKSVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASANEPEYMEEVRRQHMDRCTSFLVDELRVVDRSHAGDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARMFEFQNFERRFEECISQSAVKTKFEQHTTRAKQISEALRLIMDSVHIAAQEQRIHCLEMKEEREDRLEFIDKQLDLLTLDCKSKIKKITEEVEKQVSNAMAEEIRRLAVLVDDFHMDFHPSPVVLKVYKNELHRHIEEGLGRNMSERCSSAITVALQTTQTDMIDGLKPLLPITIREQVDKMVPRQCFALSYDLN--CDKLCSDFQEDIGFHFSLG-WTMLVNRFLGPKNTRRALMGYNDQVPRSLAITPVSTSMPPFPQGSMTQEELMVSMVTGLASL-TSRTSMGIIVVGGVIWKAVGWRLIALSVGLYGLLYVYERLTWTTRAKERTFKRQFVDYASEKLQLIVSYTGSNCSHQVQQELASTFSQLCQQVDVTRQQLEDEIGDLNSKIEQL-DTLQS 729
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: MFN1 (mitofusin 1a [Source:NCBI gene;Acc:100329462]) HSP 1 Score: 250.751 bits (639), Expect = 6.362e-75 Identity = 143/369 (38.75%), Postives = 214/369 (57.99%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXX-XXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTT 1312
I + K I +L+R+ MK AFFGRTSNGKS++IN+ML +++LP GIGHTT+CF+ ++GT ++ T D K I +V L+HAL ++ S L+ ++WP C LL+ ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+EST+ TEK FFHKV ++SKPNIFILNNRWDA E + + +KQH RC+ FL EL+V +A +RIFFVSAKE+L R L +R F FER+ E+ + SA+KTKF H+++ +++E + I+ +N +++ + + ++N + + ++I +I +V D + K T
Sbjct: 58 IQTCFRKLTVIKDVLDRRHMKVAFFGRTSNGKSTIINAMLRERVLPSGIGHTTNCFLSVEGTDGEQAYLT-----TEDSEERK----------GIETVNHLAHALHMNRNQDSGCLVRVFWPKTKCVLLRDDLVLMDSPGIDVTSELDSWIDKFCLDADVFVLVANSESTIMNTEKHFFHKVNERISKPNIFILNNRWDASVLEPEYLEDVRKQHMDRCVSFLVDELKVVDLNKAPDRIFFVSAKEVLSARIHRAQGMPETGGALAEGFQERLMEFQSFERTFEEFISQSAVKTKFEQHTIRAWQIIESVKAIMDAINISSAEKKVFSLEDREALMDRLEFVRNQLNFITEDIKDKIKVVSDEVAAKVT 411
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 325.865 bits (834), Expect = 1.058e-99 Identity = 218/693 (31.46%), Postives = 368/693 (53.10%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLK-------ESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI-DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVF-------SNALLLSYE---ARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+ ++ K I +L R+ MK AFFGRTS+GKS+VINSML K+LP GIGHTT+CF+ ++GT ++ M +G++ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FF+KV KLSKPNIFILNNRW + + + + +KQH +RC FL EL+V EA +RIFFVSAKE+L R + L R+ F +FE+ E+ + SA+KTKF H++ ++ + + I+ +N + A DK+++ ++ + +K + + I K+I + + + + ++ EI HL+ +V F + F P + + +YK ELN H+E M ++A+ C+ A+ I ++ +ID+ LL + D++ I + + + I C + S+F+ED+ F++ S+ ++ LLL + ++ NP Q ++ +M ++ ++ ++ + + +I + G+R+I+ + +YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++++L K + +D I K EI L I ++ + I+ L F + +L
Sbjct: 73 VKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYL--------------MTEGSE-EKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECISQSAVKTKFEQHTITAKQITDTVKAIMDAINIK-------AADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAMMDEIYHLSLLVDKFDAEFHPSLSVLKLYKNELNLHIENGMGRKLADRCSNAVNMSIQKAQEDIIDKLMPLLPPSVQDQTTISLPCKKFDLSYNINCEKLCSDFQEDVEFRFSFGLTSLANRFLGCKTSHLLLGFAEPITPSATGNPVLPPQPASQE-ELMLSVMSGLASL-TSRGSMSVIIVGGVIWRTVGWRLISGMMLAYGGLYLYERLTWTTRAKERAFKKQFVNYAAQKLKLIVSFTSANCSQQVQKELDNTFKRLCQQVDVTERDLAESIDKLSEEIHQLEQIQSNSKALRNRASRIEGELRNFAKSFL 741
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 324.324 bits (830), Expect = 4.292e-99 Identity = 218/698 (31.23%), Postives = 368/698 (52.72%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLK-------ESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI-DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVF-------SNALLLSYE--------ARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+ ++ K I +L R+ MK AFFGRTS+GKS+VINSML K+LP GIGHTT+CF+ ++GT ++ M +G++ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FF+KV KLSKPNIFILNNRW + + + + +KQH +RC FL EL+V EA +RIFFVSAKE+L R + L R+ F +FE+ E+ + SA+KTKF H++ ++ + + I+ +N + A DK+++ ++ + +K + + I K+I + + + + ++ EI HL+ +V F + F P + + +YK ELN H+E M ++A+ C+ A+ I ++ +ID+ LL + D++ I + + + I C + S+F+ED+ F++ S+ ++ LLL + ++ NP Q ++ +M ++ ++ ++ + + +I + G+R+I+ + +YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++++L K + +D I K EI L I ++ + I+ L F + +L
Sbjct: 73 VKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYL--------------MTEGSE-EKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECISQSAVKTKFEQHTITAKQITDTVKAIMDAINIK-------AADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAMMDEIYHLSLLVDKFDAEFHPSLSVLKLYKNELNLHIENGMGRKLADRCSNAVNMSIQKAQEDIIDKLMPLLPPSVQDQTTISLPCKKFDLSYNINCEKLCSDFQEDVEFRFSFGLTSLANRFLGCKTSHLLLGFAEPMFQVRYTPSATGNPVLPPQPASQE-ELMLSVMSGLASL-TSRGSMSVIIVGGVIWRTVGWRLISGMMLAYGGLYLYERLTWTTRAKERAFKKQFVNYAAQKLKLIVSFTSANCSQQVQKELDNTFKRLCQQVDVTERDLAESIDKLSEEIHQLEQIQSNSKALRNRASRIEGELRNFAKSFL 746
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 323.939 bits (829), Expect = 6.648e-99 Identity = 218/698 (31.23%), Postives = 368/698 (52.72%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLK-------ESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI-DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVF-------SNALLLSYE--------ARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+ ++ K I +L R+ MK AFFGRTS+GKS+VINSML K+LP GIGHTT+CF+ ++GT ++ M +G++ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FF+KV KLSKPNIFILNNRW + + + + +KQH +RC FL EL+V EA +RIFFVSAKE+L R + L R+ F +FE+ E+ + SA+KTKF H++ ++ + + I+ +N + A DK+++ ++ + +K + + I K+I + + + + ++ EI HL+ +V F + F P + + +YK ELN H+E M ++A+ C+ A+ I ++ +ID+ LL + D++ I + + + I C + S+F+ED+ F++ S+ ++ LLL + ++ NP Q ++ +M ++ ++ ++ + + +I + G+R+I+ + +YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++++L K + +D I K EI L I ++ + I+ L F + +L
Sbjct: 68 VKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYL--------------MTEGSE-EKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECISQSAVKTKFEQHTITAKQITDTVKAIMDAINIK-------AADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAMMDEIYHLSLLVDKFDAEFHPSLSVLKLYKNELNLHIENGMGRKLADRCSNAVNMSIQKAQEDIIDKLMPLLPPSVQDQTTISLPCKKFDLSYNINCEKLCSDFQEDVEFRFSFGLTSLANRFLGCKTSHLLLGFAEPMFQVRYTPSATGNPVLPPQPASQE-ELMLSVMSGLASL-TSRGSMSVIIVGGVIWRTVGWRLISGMMLAYGGLYLYERLTWTTRAKERAFKKQFVNYAAQKLKLIVSFTSANCSQQVQKELDNTFKRLCQQVDVTERDLAESIDKLSEEIHQLEQIQSNSKALRNRASRIEGELRNFAKSFL 741
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 323.553 bits (828), Expect = 7.182e-99 Identity = 218/701 (31.10%), Postives = 368/701 (52.50%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLK-------ESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI-DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVF-------SNALLLSY-----------EARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+ ++ K I +L R+ MK AFFGRTS+GKS+VINSML K+LP GIGHTT+CF+ ++GT ++ M +G++ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FF+KV KLSKPNIFILNNRW + + + + +KQH +RC FL EL+V EA +RIFFVSAKE+L R + L R+ F +FE+ E+ + SA+KTKF H++ ++ + + I+ +N + A DK+++ ++ + +K + + I K+I + + + + ++ EI HL+ +V F + F P + + +YK ELN H+E M ++A+ C+ A+ I ++ +ID+ LL + D++ I + + + I C + S+F+ED+ F++ S+ ++ LLL + ++ NP Q ++ +M ++ ++ ++ + + +I + G+R+I+ + +YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++++L K + +D I K EI L I ++ + I+ L F + +L
Sbjct: 58 VKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYL--------------MTEGSE-EKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECISQSAVKTKFEQHTITAKQITDTVKAIMDAINIK-------AADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAMMDEIYHLSLLVDKFDAEFHPSLSVLKLYKNELNLHIENGMGRKLADRCSNAVNMSIQKAQEDIIDKLMPLLPPSVQDQTTISLPCKKFDLSYNINCEKLCSDFQEDVEFRFSFGLTSLANRFLGCKTSHLLLGFAEPMFQIPRPVSTPSATGNPVLPPQPASQE-ELMLSVMSGLASL-TSRGSMSVIIVGGVIWRTVGWRLISGMMLAYGGLYLYERLTWTTRAKERAFKKQFVNYAAQKLKLIVSFTSANCSQQVQKELDNTFKRLCQQVDVTERDLAESIDKLSEEIHQLEQIQSNSKALRNRASRIEGELRNFAKSFL 734
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 323.168 bits (827), Expect = 1.201e-98 Identity = 218/701 (31.10%), Postives = 368/701 (52.50%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLK-------ESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI-DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVF-------SNALLLSY-----------EARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+ ++ K I +L R+ MK AFFGRTS+GKS+VINSML K+LP GIGHTT+CF+ ++GT ++ M +G++ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FF+KV KLSKPNIFILNNRW + + + + +KQH +RC FL EL+V EA +RIFFVSAKE+L R + L R+ F +FE+ E+ + SA+KTKF H++ ++ + + I+ +N + A DK+++ ++ + +K + + I K+I + + + + ++ EI HL+ +V F + F P + + +YK ELN H+E M ++A+ C+ A+ I ++ +ID+ LL + D++ I + + + I C + S+F+ED+ F++ S+ ++ LLL + ++ NP Q ++ +M ++ ++ ++ + + +I + G+R+I+ + +YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++++L K + +D I K EI L I ++ + I+ L F + +L
Sbjct: 68 VKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYL--------------MTEGSE-EKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECISQSAVKTKFEQHTITAKQITDTVKAIMDAINIK-------AADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAMMDEIYHLSLLVDKFDAEFHPSLSVLKLYKNELNLHIENGMGRKLADRCSNAVNMSIQKAQEDIIDKLMPLLPPSVQDQTTISLPCKKFDLSYNINCEKLCSDFQEDVEFRFSFGLTSLANRFLGCKTSHLLLGFAEPMFQIPRPVSTPSATGNPVLPPQPASQE-ELMLSVMSGLASL-TSRGSMSVIIVGGVIWRTVGWRLISGMMLAYGGLYLYERLTWTTRAKERAFKKQFVNYAAQKLKLIVSFTSANCSQQVQKELDNTFKRLCQQVDVTERDLAESIDKLSEEIHQLEQIQSNSKALRNRASRIEGELRNFAKSFL 744
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn1 (mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]) HSP 1 Score: 340.117 bits (871), Expect = 3.677e-105 Identity = 222/700 (31.71%), Postives = 372/700 (53.14%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVF------SNA-----------------LLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
I K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGHTT+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + ++QH +RC+ FL +EL+V + EA RIFFVSAKE+L R + L R + F FE++ E+ + SA+KTKF H+++ ++++ + NIL +N +++++ + D I+N + + ++ K+I V + + K + ++ EI L+ +V F S F P P+ + +YK+ELN H+E M +A+ C + I+ ++ +I+ LL I + +I + DL+ + C+ + S+F+ED+ F++ L S+ +NA L + A ++ PD+ Q +M + ++ ++ +G + +I K G+++I+ +L YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++Q++ + +D + EI + EI L I ++ ++++ L F +++L
Sbjct: 57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGRNLADRCTNEVNASILQSQQEIIENLKPLLPAGIQNKLHTLIP-CKKFDLSYDLNCHKLCSDFQEDIVFRFSLGWSSLVHRFLGSTNAQRVLLGLSEPIFQVPRSLASTPTAPSNPAAPDNAAQE-----ELMITLITGLASL-TSRTSMGIIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVSFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSKLLRNKAVQLESELENFSKQFL 734
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn1 (mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]) HSP 1 Score: 340.117 bits (871), Expect = 3.677e-105 Identity = 222/700 (31.71%), Postives = 372/700 (53.14%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVF------SNA-----------------LLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
I K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGHTT+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + ++QH +RC+ FL +EL+V + EA RIFFVSAKE+L R + L R + F FE++ E+ + SA+KTKF H+++ ++++ + NIL +N +++++ + D I+N + + ++ K+I V + + K + ++ EI L+ +V F S F P P+ + +YK+ELN H+E M +A+ C + I+ ++ +I+ LL I + +I + DL+ + C+ + S+F+ED+ F++ L S+ +NA L + A ++ PD+ Q +M + ++ ++ +G + +I K G+++I+ +L YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++Q++ + +D + EI + EI L I ++ ++++ L F +++L
Sbjct: 57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGRNLADRCTNEVNASILQSQQEIIENLKPLLPAGIQNKLHTLIP-CKKFDLSYDLNCHKLCSDFQEDIVFRFSLGWSSLVHRFLGSTNAQRVLLGLSEPIFQVPRSLASTPTAPSNPAAPDNAAQE-----ELMITLITGLASL-TSRTSMGIIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVSFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSKLLRNKAVQLESELENFSKQFL 734
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]) HSP 1 Score: 328.561 bits (841), Expect = 1.086e-100 Identity = 207/628 (32.96%), Postives = 340/628 (54.14%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTD-KVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-----RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV-----------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
K I +L R+ MK AFFGRTSNGKS+VIN+ML K+LP GIGHTT+CF+++ GT F+ + +G++ + + +V L+HAL D ++ + S++ + WP+ C LLK ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK FFHKV +LS+PNIFILNNRW + + + + ++QH +RC FL EL V +A +RIFFVSAKE+L R + L R F FER E+ + SA+KTKF H+++ ++ E + I+ L+ Q ++ ++ ++ +R K D ++ I + + + + + ++ EI+ L+ +V + F P P + +YK EL+ H+E+ + +++ C+ AI + ++ +ID LL + R+ ID++ L+ + C+ + ++F+ED+ F + L ++ N L +R ++ D V QS Q +M + ++ ++ +G + ++ K G+R+I S YGLLY+YER+ W+ +E+ FK Q+V+YAS +L +I N S ++Q+L
Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFL--------------LTEGSE-EKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHIAAQEQRVYCLEMREERQDRLRFIDKQLELLAQDYKLR-IKQITEEVERQVSTAMAEEIRRLSVLVDEYQMDFHPSPVVLKVYKNELHRHIEEGLGRNLSDRCSTAIASSLQTMQQDMIDGLKPLLPVSM-RNQIDMLVPRQCFSLSYDLNCDKLCADFQEDIEFHFSLG-WTMLVNRFLGPKNSRRALLGYSDQVQRPLPLTPANPSMPPLPQSSLTQEELMVSMVTGLASL-TSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEYASEKLQLIISYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]) HSP 1 Score: 328.561 bits (841), Expect = 1.086e-100 Identity = 207/628 (32.96%), Postives = 340/628 (54.14%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTD-KVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-----RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV-----------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
K I +L R+ MK AFFGRTSNGKS+VIN+ML K+LP GIGHTT+CF+++ GT F+ + +G++ + + +V L+HAL D ++ + S++ + WP+ C LLK ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK FFHKV +LS+PNIFILNNRW + + + + ++QH +RC FL EL V +A +RIFFVSAKE+L R + L R F FER E+ + SA+KTKF H+++ ++ E + I+ L+ Q ++ ++ ++ +R K D ++ I + + + + + ++ EI+ L+ +V + F P P + +YK EL+ H+E+ + +++ C+ AI + ++ +ID LL + R+ ID++ L+ + C+ + ++F+ED+ F + L ++ N L +R ++ D V QS Q +M + ++ ++ +G + ++ K G+R+I S YGLLY+YER+ W+ +E+ FK Q+V+YAS +L +I N S ++Q+L
Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFL--------------LTEGSE-EKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHIAAQEQRVYCLEMREERQDRLRFIDKQLELLAQDYKLR-IKQITEEVERQVSTAMAEEIRRLSVLVDEYQMDFHPSPVVLKVYKNELHRHIEEGLGRNLSDRCSTAIASSLQTMQQDMIDGLKPLLPVSM-RNQIDMLVPRQCFSLSYDLNCDKLCADFQEDIEFHFSLG-WTMLVNRFLGPKNSRRALLGYSDQVQRPLPLTPANPSMPPLPQSSLTQEELMVSMVTGLASL-TSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEYASEKLQLIISYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]) HSP 1 Score: 328.561 bits (841), Expect = 1.086e-100 Identity = 207/628 (32.96%), Postives = 340/628 (54.14%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTD-KVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-----RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV-----------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
K I +L R+ MK AFFGRTSNGKS+VIN+ML K+LP GIGHTT+CF+++ GT F+ + +G++ + + +V L+HAL D ++ + S++ + WP+ C LLK ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK FFHKV +LS+PNIFILNNRW + + + + ++QH +RC FL EL V +A +RIFFVSAKE+L R + L R F FER E+ + SA+KTKF H+++ ++ E + I+ L+ Q ++ ++ ++ +R K D ++ I + + + + + ++ EI+ L+ +V + F P P + +YK EL+ H+E+ + +++ C+ AI + ++ +ID LL + R+ ID++ L+ + C+ + ++F+ED+ F + L ++ N L +R ++ D V QS Q +M + ++ ++ +G + ++ K G+R+I S YGLLY+YER+ W+ +E+ FK Q+V+YAS +L +I N S ++Q+L
Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFL--------------LTEGSE-EKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHIAAQEQRVYCLEMREERQDRLRFIDKQLELLAQDYKLR-IKQITEEVERQVSTAMAEEIRRLSVLVDEYQMDFHPSPVVLKVYKNELHRHIEEGLGRNLSDRCSTAIASSLQTMQQDMIDGLKPLLPVSM-RNQIDMLVPRQCFSLSYDLNCDKLCADFQEDIEFHFSLG-WTMLVNRFLGPKNSRRALLGYSDQVQRPLPLTPANPSMPPLPQSSLTQEELMVSMVTGLASL-TSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEYASEKLQLIISYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7YU24|MARF_DROME (Transmembrane GTPase Marf OS=Drosophila melanogaster OX=7227 GN=Marf PE=1 SV=1) HSP 1 Score: 348.206 bits (892), Expect = 1.032e-106 Identity = 229/675 (33.93%), Postives = 373/675 (55.26%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-------RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNS---KVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYE-IDRSMIDVIERTSEHDL--TIPCNTIFSNFKEDLSFQ--WPLNP----------------------------HSVFSNALLLSYEARNSMNNPDDNVQSLR-RQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEI 2134
K I +L+R MK AFFGRTSNGKSSVIN+ML +KILP GIGHTT+CF Q++G++ ++ M +G++ + L + ++ L++AL +K+ SL+ ++WP + C LL+ +V F+DSPGVD+ +LD WI+++CL+ADVFVLV NAEST+T+ EK FFH V KLSKPNIFILNNRWDA +E + + K QH +RCIDFLTKEL+V +EA ER+FFVSA+E L+ R E + N P + RY F FER E+ + SA+KTKF HS +G + M ++L + ++I + N+ D+K + + ++I+ + +V + +I +++ + K +++L EI L ++ F PF P+ ++IYK ELN HVE + + + + A+ + + + D+ L+ E + + ++ RT ++ ++ C + ++F+EDL F+ W + HSV S EA P V + QL+++ F S ++ VG ++ ++ K G+RV+ YG +YLYER+ W+ S +E+ FK+QYV++A+ +L ++D+ + N S ++Q+L + +D ++E++ +S++
Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYL--------------MTEGSE-EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEE--AKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVSGDMKSMLDNIYERITIFRNLKQDQK---NLLTERIQGTETQMMQVTREMKMKIHNMVEEVEEKVSKALNEEIWRLGVLIDEFNMPFHPERLVLNIYKKELNAHVESGLGSNLRARLSMALAMNVESAQTEMTDRMHALVPNEQLLATSTKMVVRTQPFEMLYSLNCQNLCADFQEDLEFKFSWGIAAMIQRFTGKVRERSKKGQPALVNRQSSIGHSV-STPTTTPVEATPVCLLPAPVVAGITPEQLSLISRFAVSS---IGSQGTVGGLVVAGVMLKTIGWRVLVGVGALYGCIYLYERLSWTNSAKERTFKSQYVRHATKKLKMIVDLTSANCSHQVQQELSSTFARLCRTVDTATTDMNDELKTLDSQL 775
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R4Z9|MFN1_RAT (Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 PE=1 SV=1) HSP 1 Score: 341.658 bits (875), Expect = 5.329e-105 Identity = 223/700 (31.86%), Postives = 374/700 (53.43%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVF------SNA-----------------LLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
I K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGHTT+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + ++QH +RC+ FL +EL+V + EA RIFFVSAKE+L R ++ L R + F FE++ E+ + SA+KTKF H+++ ++++ + NIL +N +++++ + D I+N + + ++ K+I V + + K + ++ EI L+ +V F S F P P+ + +YK+ELN H+E M +A+ C + I+ ++ +I+ LL I + +I + DL+ + C+ + S+F+ED+ F++ L S+ +NA L + A ++ PD+ Q +M + ++ ++ +G + +I K G+++I+ +L YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++Q++ + +D + EI + EI L I ++ ++++R L F +++L
Sbjct: 57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPLEARNRIFFVSAKEVLNSRMNKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTMDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGRNLADRCTSEVNASILQSQQEIIENLKPLLPAGIQNKLHTLIP-CKKFDLSYDLNCHKLCSDFQEDIVFRFSLGWSSLVHRFLGSTNAQRVLLGLSEPIFQVPRSLASTPTAPSNPAAPDNAAQE-----ELMITLITGLASL-TSRTSMGIIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVKFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSKLLRNKAVQLERELENFSKQFL 734
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q811U4|MFN1_MOUSE (Mitofusin-1 OS=Mus musculus OX=10090 GN=Mfn1 PE=1 SV=3) HSP 1 Score: 340.117 bits (871), Expect = 2.572e-104 Identity = 222/700 (31.71%), Postives = 372/700 (53.14%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVF------SNA-----------------LLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
I K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGHTT+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + ++QH +RC+ FL +EL+V + EA RIFFVSAKE+L R + L R + F FE++ E+ + SA+KTKF H+++ ++++ + NIL +N +++++ + D I+N + + ++ K+I V + + K + ++ EI L+ +V F S F P P+ + +YK+ELN H+E M +A+ C + I+ ++ +I+ LL I + +I + DL+ + C+ + S+F+ED+ F++ L S+ +NA L + A ++ PD+ Q +M + ++ ++ +G + +I K G+++I+ +L YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S ++Q++ + +D + EI + EI L I ++ ++++ L F +++L
Sbjct: 57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGRNLADRCTNEVNASILQSQQEIIENLKPLLPAGIQNKLHTLIP-CKKFDLSYDLNCHKLCSDFQEDIVFRFSLGWSSLVHRFLGSTNAQRVLLGLSEPIFQVPRSLASTPTAPSNPAAPDNAAQE-----ELMITLITGLASL-TSRTSMGIIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVSFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSKLLRNKAVQLESELENFSKQFL 734
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8IWA4|MFN1_HUMAN (Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 SV=3) HSP 1 Score: 328.946 bits (842), Expect = 4.198e-100 Identity = 219/691 (31.69%), Postives = 367/691 (53.11%), Query Frame = 2
Query: 242 EKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCN--TIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQL-------------------NVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+K I +L R+ MK AFFGRTS+GKSSVIN+ML K+LP GIGH T+CF+ ++GT ++ M +G+ + + +V L+HAL DK + + L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + ++QH +RC+ FL +EL+V EA RIFFVSAKE+L R + + L R + F FE+ E+ + SA+KTKF H+++ +++ + NI+ +N + + +V+++ + D I+N + + ++ K+I V + + K + ++ EI L+ +V F S F P+P + IYK+ELN H+E M +A+ C + ++ ++ +I+ LL I + +I + DL+ N + S+F+ED+ F++ L S+ + L A+ + + + L R L +M + ++ ++ +G + +I K G+++++ SL YG LYLYER+ W+ +E+ FK Q+V YA+ +L ++ + N S +KQ + + +D + + EI + EI L I ++ ++++ L F +++L
Sbjct: 62 DKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYL--------------MTEGSD-EKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIP-CKKFDLSYNLNYHKLCSDFQEDIVFRFSLGWSSLV-HRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNASQEELMITLVTGLASV-TSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAKERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFL 734
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|O95140|MFN2_HUMAN (Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3) HSP 1 Score: 328.946 bits (842), Expect = 4.900e-100 Identity = 213/630 (33.81%), Postives = 339/630 (53.81%), Query Frame = 2
Query: 245 KCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD-----RYENFLQFERSLEKNLCASALKTKFASHSLQG---LELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSF-KNIFVNKEFV----------------GFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
K I +L R+ MK AFFGRTSNGKS+VIN+ML K+LP GIGHTT+CF++++GT F+ + +G++ + +V L+HAL DK + + SL+ + WP+ C LLK ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK FFHKV +LS+PNIFILNNRW + + + + ++QH +RC FL EL V +A +RIFFVSAKE+L R + L R F FER E+ + SA+KTKF H+++ E V ++++ LH + Q+ +++ DK ++ +KQI+ + + + + ++ EI+ L+ +V ++ F P P + +YK EL+ H+E+ + +++ C+ AI + ++ +ID LL + RS ID++ L + C+ + ++F+ED+ F + L ++ N L +R ++ +D VQ L P + + +EF+ G + ++ K G+R+I S YGLLY+YER+ W+ +E+ FK Q+V++AS +L VI N S ++Q+L
Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFL--------------LTEGSE-EKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQIT---EEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMIDGLKPLLPVSV-RSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLG-WTMLVNRFLGPKNSRRALMGYNDQVQR-PIPLTPANPSMPPLPQGSLTQEEFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A183T2P8 (Mitofusin-2 OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS10746 PE=3 SV=1) HSP 1 Score: 442.195 bits (1136), Expect = 1.323e-140 Identity = 258/700 (36.86%), Postives = 392/700 (56.00%), Query Frame = 2
Query: 218 QDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGF--IVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD------------------RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI--DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNS-----MNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+D IN E+ + I I+ R +MKCAFFGRTSNGKS+VIN+MLG +ILP GIGHTTSCFVQI+GT + GF +V + + T+ + + + PI SV L+HALS+DK++++SL+ LYWP+ NC LL+ +V LDSPGV++DPD+D WI+ +CLDADVF+LVANAESTL Q EK FFH+V +K+SKPNIFILNNRW + + + K+QH QRC+ FL EL+VC +EA ER+FFVSA+E+L R +++S P R F FE+ EK L SA +TKFA+H+ QG EL I+ + + A+ ++L ES + ++++ K + I + IS L ++ + +L EI+ LN +V NF PF DP+ + YK +LN +E+E+ ++ CAG I +++ ++ + Y L+ E +R M V+ + E + + C I + F+EDLSF++ L S + L S R S +P V +L+ + P + S + + VG + I K G+RVI Y LY YER+ W+ +E+ FK QYV YAS++L ++D+ N +K++L H+ + + E+ + +S+I+ L +I + + + + L +F + Y+
Sbjct: 76 EDDINPYYERVKHIQEIIARNQMKCAFFGRTSNGKSTVINAMLGSRILPAGIGHTTSCFVQIEGTDQSQGFTRLVNSTDTTAATGDSSNPRAEVLPDQPIESVSQLAHALSSDKLATDSLVCLYWPNANCHLLREDVVLLDSPGVNVDPDMDRWIDQHCLDADVFILVANAESTLMQAEKDFFHRVSSKISKPNIFILNNRWDASAGEVEYADQVKEQHLQRCVSFLADELKVCGRDEAMERVFFVSAREVLTVR-AKSSSNCTPPGAAPNIGLPSAGGYPLAEGWQARLLEFSTFEKVFEKILSDSATRTKFAAHTEQGKELAAHFRGIMETTYEAALEEKDAAIRYRRLSESRL-EELRTKLQKASQAIEELISKCLIDVEGQVANALCSEIRRLNELVDNFDRPFSSDPSPLQFYKRDLNAFIERELGRKLGEACAGDIHSQVVRAEQFMAGLYASLVPEESSKNRIMQSVLAASFEPEFHVDCRNICAEFREDLSFRFSLG-LSTLAQKLFHSPRERMSWAQGYAGSPSHAVA----ELSPVLPAIFSHLPSLLGRNTVGLAVVGGFILKAAGWRVIFLCAGLYAGLYAYERLTWTSRAREEVFKRQYVAYASHKLRLIVDLTGTNARHQVKRELQQIHRRLAAEGEDAATGLARELDQLDSDIVTLNEITVAAKTLKNNAVYLDSCLNKFNQDYI 768
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A0X3PID4 (Dynamin-type G domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR117163 PE=3 SV=1) HSP 1 Score: 441.81 bits (1135), Expect = 1.903e-140 Identity = 255/674 (37.83%), Postives = 382/674 (56.68%), Query Frame = 2
Query: 218 QDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGF--IVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD------------------RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI--DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNS-----MNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDI 2152
+D IN E+ + I I+ R +MKCAFFGRTSNGKS+VIN+MLG +ILP GIGHTTSCFVQI+GT + GF +V + + T+ + + + PI SV L+HALS+DK++++SL+ LYWP+ NC LL+ +V LDSPGV++DPD+D WI+ +CLDADVF+LVANAESTL Q EK FFH+V +K+SKPNIFILNNRW + + + K+QH QRC+ FL EL+VC +EA ER+FFVSA+E+L R +++S P R F FE+ EK L SA +TKFA+H+ QG EL I+ + + A+ ++L ES + ++++ K + I + IS L ++ + +L EI+ LN +V NF PF DP+ + YK +LN +E+E+ ++ CAG I +++ ++ + Y L+ E +R M V+ + E + + C I + F+EDLSF++ L S + L S R S +P V +L+ + P + S + + VG + I K G+RVI Y LY YER+ W+ +E+ FK QYV YAS++L ++D+ N +K++L H+ + + E+ + +S+I+ L +I
Sbjct: 76 EDDINPYYERVKHIQEIIARNQMKCAFFGRTSNGKSTVINAMLGSRILPAGIGHTTSCFVQIEGTDQSQGFTRLVNSTDTTAATGDSSNPRAEVLPDQPIESVSQLAHALSSDKLATDSLVCLYWPNANCHLLREDVVLLDSPGVNVDPDMDRWIDQHCLDADVFILVANAESTLMQAEKDFFHRVSSKISKPNIFILNNRWDASAGEVEYADQVKEQHLQRCVSFLADELKVCGRDEAMERVFFVSAREVLTVR-AKSSSNCTPPGAAPNIGLPSAGGYPLAEGWQARLLEFSTFEKVFEKILSDSATRTKFAAHTEQGKELAAHFRGIMETTYEAALEEKDAAIRYRRLSESRL-EELRTKLQKASQAIEELISKCLIDVEGQVANALCSEIRRLNELVDNFDRPFSSDPSPLQFYKRDLNAFIERELGRKLGEACAGDIHSQVVRAEQFMAGLYASLVPEESSKNRIMQSVLAASFEPEFHVDCRNICAEFREDLSFRFSLG-LSTLAQKLFHSPRERMSWAQGYAGSPSHAVA----ELSPVLPAIFSHLPSLLGRNTVGLAVVGGFILKAAGWRVIFLCAGLYAGLYAYERLTWTSRAREEVFKRQYVAYASHKLRLIVDLTGTNARHQVKRELQQIHRRLAAEGEDAATGLARELDQLDSDIVTLNEI 742
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A0V0JBI8 (Mitofusin-2 (Fragment) OS=Schistocephalus solidus OX=70667 GN=MFN2 PE=3 SV=1) HSP 1 Score: 436.032 bits (1120), Expect = 6.551e-139 Identity = 249/638 (39.03%), Postives = 369/638 (57.84%), Query Frame = 2
Query: 218 QDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGF--IVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLD------------------RYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEI--DRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYE----ARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
+D IN E+ + I I+ R +MKCAFFGRTSNGKS+VIN+MLG +ILP GIGHTTSCFVQI+GT + GF +V + + T+ + + + PI SV L+HALS+DK++++SL+ LYWP+ NC LL+ +V LDSPGV++DPD+D WI+ +CLDADVF+LVANAESTL Q EK FFH+V +K+SKPNIFILNNRW + + + K+QH QRC+ FL EL+VC +EA ER+FFVSA+E+L R +++S P R F FE+ EK L SA +TKFA+H+ QG EL I+ + + A+ ++L ES + ++++ K + I + IS L ++ + +L EI+ LN +V NF PF DP+ + YK +LN +E+E+ ++ CAG I +++ ++ + Y L+ E +R M V+ + E + I C I + F+EDLSF++ L ++ L S E A+ +P V +L+ + P + S + + VG + K G+RVI + Y LY YER+ W+ S +E+ FK QYV YAS++L ++D+ N +K++L
Sbjct: 76 EDDINPYYERVKHIQEIIARNQMKCAFFGRTSNGKSTVINAMLGSRILPAGIGHTTSCFVQIEGTDQSQGFTRLVNSTDTTAATGDSSNPRAEVLPDQPIESVSQLAHALSSDKLATDSLVCLYWPNANCHLLREDVVLLDSPGVNVDPDMDRWIDQHCLDADVFILVANAESTLMQAEKDFFHRVSSKISKPNIFILNNRWDASAGEVEYADQVKEQHLQRCVSFLADELKVCGRDEAMERVFFVSAREVLTVR-AKSSSNCTPPGAAPNIGLPSAGGYPLAEGWQARLLEFSTFEKVFEKILSDSATRTKFAAHTEQGKELAAHFRGIMETTYEAALEEKDAAIRYRRLSESRL-EELRTKLQKASQAIEELISKCLIDVEGQVANALCSEIRRLNELVDNFDRPFSSDPSPLQFYKRDLNAFIERELGRKLGEACAGDIHSQVVRAEQFMAGLYASLVPDESSKNRIMQSVLAASYEPEFHIDCRNICAEFREDLSFRFSLGLSTLAQKLLHPSREETSWAQGYAGSPLHAVA----ELSPVLPTVLSHLPTLLGRSTVGLAVFGGCVFKAAGWRVIFLCVGLYAGLYAYERLTWTSSAREELFKRQYVAYASHKLRLIVDLTGTNARHQVKREL 707
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: C1L4S5 (Mitofusin 2 OS=Schistosoma japonicum OX=6182 GN=Mfn2 PE=2 SV=1) HSP 1 Score: 422.935 bits (1086), Expect = 4.048e-133 Identity = 254/690 (36.81%), Postives = 401/690 (58.12%), Query Frame = 2
Query: 179 TEYDANANFLGE-YQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXX-XXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSEN--------------SYRSNNPKVL-------DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMI-DVIERTS-EHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIF---VNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKS 2161
+E + A LGE I +K I I+ R +MKCAFFGRTSNGKS+VIN+MLG K+LP G+GHTTSCF++IQGT G+++ + TS + T+ PI SV L+HALS K+S+++L+ ++WP +C LL+ +V LDSPG+++DPD+D WI+ +CLDADVF+LVANAESTL QTEK FFHKV KLSKPNIFI+NNRWDA + + V ++QH QRC+ FL EL+VCT EA +FFVSA+E+L RT N S S P V DR F FE EKNL SA +TKFA+HS QG +LV I+ + + + AV ++L ++H+ ++++ K + + + L + + +L VEI+ LN +V +++ PF PDPA +H+YK ELN HVE+E+ ++ C+ I E+ ++ +++++ ++ E ++ I +I+ T+ + + C + +NF+ED+ F++ L+ ++F + N D + S +++ P + ++F +++ VG I ++ K G+RV+ + YG LYL+ER+ W+ +E FK QYV +AS++L ++D+ + N +K++L + HK + ++ E+++ +++II L D++ S
Sbjct: 58 SEEEKFARLLGEGVCTEIGHHLQKVRNIQDIIARNQMKCAFFGRTSNGKSTVINAMLGSKLLPSGLGHTTSCFLEIQGTDQDCGYLLMAGSDTSTTDTADASHQTR----PIDSVGQLAHALSNVKLSADTLLKIFWPSSHCRLLREDVVLLDSPGINVDPDMDKWIDLHCLDADVFILVANAESTLMQTEKDFFHKVSQKLSKPNIFIINNRWDASANEIEYVNEVREQHLQRCVAFLVDELKVCTRAEADGHVFFVSAREVLAMRTRANLGENMHSGPPGAATSIGSPLPAVAYMAEGWQDRLAEFTNFETVFEKNLSESATRTKFAAHSEQGKDLVNRFRAIMESIYETTVEEKDAAVRCRRLSQAHL-EEVRARLMKTTQAVDEMLHASLARVEAQVASALNVEIRRLNELVDSYSRPFHPDPALIHVYKRELNTHVERELGRKLTEACSSDILNEVARCEQLMMNKHASIVSDEACKNRILQLIDPTAFSPEFHLDCRNLCANFREDIQFRFSLSLGTLFQRLSVPRRSISNYHWTQSDGIPSSLVNSSIL-PRSSLTVDLFPSLMSRSAVGTVIILGIMSKAVGWRVLAVACGIYGGLYLFERLSWTNKAKETAFKRQYVDFASHKLRLIVDLTSTNARHQVKRELHLAHKKLCSEVENFSDTLVEEVKQLDNDIIRL-DLITS 740
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A068WQF3 (Transmembrane gtpase mfn mitofusin 1 fzo OS=Echinococcus granulosus OX=6210 GN=EgrG_000203900 PE=3 SV=1) HSP 1 Score: 421.394 bits (1082), Expect = 1.767e-132 Identity = 250/700 (35.71%), Postives = 392/700 (56.00%), Query Frame = 2
Query: 242 EKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSE-------------NSYRSNNPKVLDRYE----NFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVD-KKLKESH---IRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTS-PFDP-DPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRS-----MIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFS--------NALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
E+ ++I SI+ R +MKCAFFGRTSNGKS+VIN+MLG +ILP GIGHTTSCFVQ+QGT+ + GF+ + SD + + + T + PI SV L+H+LS+ K++S+SLI L+WP +C LL+ +V LDSPGV++DPD+D WI+ +CLDADVF+LVANAESTL Q EK FF++V +++SKPNIFILNNRW + + + K+QH QRC+ FLT EL+VC H+EA ER+FFVSA+E+L R S + + D ++ F FE+ EK L SA +TKFASH+ QG EL ++ + + + ++L ++ +R K++N +ND I K L ++ + +L EI+ L +V +F+ F D A + Y+ ELN ++E+E+ ++A CAG I +++ ++ + Y L+ E D S M V+ + E + + C I + F+EDL F++ L S+ S N+ Q + V+ FL+S + +++ VG + ++ K TG+R+I Y LY YER+ W+ +E FK+QYV YAS++L ++D+ N +K++L K +G +G +E+ + + +++ L +I S + + + L +F ++Y+
Sbjct: 84 ERVKQIQSIISRNQMKCAFFGRTSNGKSTVINAMLGSRILPSGIGHTTSCFVQVQGTNQSQGFL--QQECISDFGSGE-ETQTLSEPRPIESVSHLAHSLSSAKMASDSLIYLFWPSSSCHLLREDVVLLDSPGVNVDPDMDAWIDRHCLDADVFILVANAESTLMQAEKDFFYRVSSRISKPNIFILNNRWDASAGEAELADQVKEQHMQRCVSFLTDELKVCGHDEAMERVFFVSAREVLTIRARSLNGGAPPGSAPNIGSPSAGGYPLADGWQARLMEFSTFEKVFEKILSDSATRTKFASHAEQGKELAAYFRQLMETTYEAALEEKDAGIRYRRLSQARLEELRAKLQNAARTINDLIAK----CLLDVEAQVANALCNEIRRLGELVDSFSGHAFAADDEATLRTYRHELNAYIERELGKKLAAACAGDIHSQVVRAEQIMASIYEGLV--EADESAKSRIMQSVLSSSFEPEFHVDCRNICAEFREDLRFRFSLGLSSLAERLLHHQRHGGFYSSGSTANTWTGGYAGSQGMPEYSPVLPLFLSSLPAL-LSRNTVGLLVVGGIVLKATGWRMIMVLGGLYAGLYAYERLAWTNRAREAAFKSQYVNYASHKLRLIVDLTGTNARHQVKRELHQMQKRLGNEGEGAAKVLSDELVQLDKDLVTLDNITTSAKTLKNGAIYLDGCLDKFHKEYI 773
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000043809.1 (mitofusin-1-like [Source:NCBI gene;Acc:103034819]) HSP 1 Score: 351.288 bits (900), Expect = 1.068e-109 Identity = 220/683 (32.21%), Postives = 362/683 (53.00%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSM-IDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPF-------LNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
I S + K E I +L R++MK AFFGRTSNGKS+VIN+ML +++LP GIGHTT+CF+ ++GT F+ ++ + I +V L+HAL D+ + S L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV ++SKPNIFILNNRW + + + + +KQH RC+ FL EL+V + ++A RIFFVSAKE L R L DR + F FER+ E+ + S++KTKF H+++ ++ E + I+ +N ++++ + D ++N + + + +I ++ D+I K +L EI+ + IV F S F P P + +YK +L +VE+ M +A C+ +I ++ ++ I+ + LL + + V R E + + S+F+ED+ FQ+ L + N L +A+ ++N D N+++ + P + + ++ + I ++ + G+RVI S+ YGLLYLYE++ W+ S +EK K Q+V+YA+ +L + + + N ++Q+L+ M +D + EIRK ++I L + + + + +++ L F YL
Sbjct: 58 IQSCSRKLEAIWEVLARRQMKVAFFGRTSNGKSTVINAMLRERVLPSGIGHTTNCFISVEGTDGDQAFLTTENSE---------------ERKSIKTVNQLAHALHMDRNLDSGCLVRVFWPKTKCALLRDDLVLMDSPGTDVTSELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVSERISKPNIFILNNRWDASETEPEYLDGVRKQHMDRCVSFLVDELKVVSPDQAPNRIFFVSAKEALSARIHRAQGMPETGAALADGFQDRLQEFQSFERTFEEFISHSSVKTKFEQHTIRAWQITESLKTIMDAINITSAEKKVLSLEDREALMDRLDFVRNQINFLTEETKDKIKVITDDIAAKVASALVEEIQGFSVIVDEFCSDFSPAPNALTLYKTKLIAYVEERMVRNLARRCSSSISGCVLSSQRDFINIISPLLPSAARGHLHMHVPSRRFEMAYELNLGALCSDFQEDIQFQFSLG-WTALVNRFLGPAKAKQALNMLDKNLRASTHPAPIGTPAQEELAVSMATGLASLTSRASMTALVIGGVVWRSVGWRVIVLSVSLYGLLYLYEKLTWTNSSREKALKQQFVEYATQRLQAISHITSSNCGLQVQQELVGVFARMCQQVDKSEMELETEIRKLNAKIQRLESVQRHSKTLRYKATDLESQLESFSTHYL 724
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239]) HSP 1 Score: 327.405 bits (838), Expect = 1.708e-100 Identity = 231/734 (31.47%), Postives = 387/734 (52.72%), Query Frame = 2
Query: 167 NKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKL----KESHIRDKIKNGNSKVNDNIVKQISIVL---DNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV------------------------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
N SL E+ A++ L E I S EK I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT + ++ KT +G++ + I +V L+HAL D+ + + L+ ++WP C LL+ ++ +DSPG D+ LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRW + + + + +KQH RC++FL +EL+V EEA IFFVSAKE+L R L DR + F FER+ E+ + SA+KTKF H+++ ++ E + +I+ DQI + A +K++ + ++ D+++ +++N I + + + K + ++ EI L+ ++ F S F P P + +YK+EL NHVEK M +A C+ A+ + +K +I+ LL + +S I ++ + DL+ + C + ++F+E++ FQ+ L ++ S L A+ ++ D N+ Q++ Q +M + ++ ++ + + ++ + G+RVI S+ YG+LYLYER+ W+ +E+ K Q+V YA+ +L ++ + N S ++Q++ + +D ++EI++ ++I L + + + ++ L +F +YL
Sbjct: 43 NTSL-EHIADSTQLQE----IESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYL-----KT---------EGSE-EEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDRCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQSFERTFEECISQSAVKTKFEQHTIRAKQITESVKDIM----DQIHI---AAAEKRVASLEEREYLMDRLEFVRNQLNILIKDIKKKIKVITEQVENKVSNAMAEEICRLSVLIDEFHSDFHPSPHILKLYKSELLNHVEKGMGKNLAFRCSDAVNASVQSSQKDMIECLQPLLPSTV-QSQIHMLIPNRKFDLSYDLNCAILCADFQENIEFQFSLGWAALVSR-FLGPANAKRALMLIDQNLKLSQPVATTPSSGPVVQAPPPGAPASQGQSQAVMTQEELMMSMATNLASL-TSRTSMSVVIVGGVVWRTIGWRVIALSMSLYGVLYLYERLTWTTKAKERALKKQFVDYATEKLQLIVSFTSSNCSHQVQQEIASTFARLCQQVDVTQRDLESEIKRLTTKIQELETVQGRSKALRHKATHLESLLEDFTRQYL 746
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239]) HSP 1 Score: 325.094 bits (832), Expect = 1.133e-99 Identity = 234/717 (32.64%), Postives = 378/717 (52.72%), Query Frame = 2
Query: 167 NKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKL----KESHIRDKIKNGNSKVNDNIVKQISIVL---DNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT--IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV------------------------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANG 2179
N SL E+ A++ L E I S EK I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT + ++ KT +G++ + I +V L+HAL D+ + + L+ ++WP C LL+ ++ +DSPG D+ LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRWDA E + + +KQH RC++FL +EL+V EEA IFFVSAKE+L R L DR + F FER+ E+ + SA+KTKF H+++ ++ E + +I+ DQI + A +K++ + ++ D+++ +++N I + + + K + ++ EI L+ ++ F S F P P + +YK+EL NHVEK M +A C+ A+ + +K +I+ LL + +S I ++ + DL+ + C + ++F+E++ FQ+ L ++ S L A+ ++ D N+ Q++ Q +M + ++ ++ + + ++ + G+RVI S+ YG+LYLYER+ W+ +E+ K Q+V YA+ +L ++ + N S ++Q++ + + D R ESEI LT ++ + G
Sbjct: 43 NTSL-EHIADSTQLQE----IESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYL-----KT---------EGSE-EEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDRCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQSFERTFEECISQSAVKTKFEQHTIRAKQITESVKDIM----DQIHI---AAAEKRVASLEEREYLMDRLEFVRNQLNILIKDIKKKIKVITEQVENKVSNAMAEEICRLSVLIDEFHSDFHPSPHILKLYKSELLNHVEKGMGKNLAFRCSDAVNASVQSSQKDMIECLQPLLPSTV-QSQIHMLIPNRKFDLSYDLNCAILCADFQENIEFQFSLGWAALVSR-FLGPANAKRALMLIDQNLKLSQPVATTPSSGPVVQAPPPGAPASQGQSQAVMTQEELMMSMATNLASL-TSRTSMSVVIVGGVVWRTIGWRVIALSMSLYGVLYLYERLTWTTKAKERALKKQFVDYATEKLQLIVSFTSSNCSHQVQQEIASTFARL-------CQQVDVTQRDLESEIKRLTTKIQELETVQG 722
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]) HSP 1 Score: 321.242 bits (822), Expect = 7.962e-98 Identity = 220/691 (31.84%), Postives = 355/691 (51.37%), Query Frame = 2
Query: 59 MTDKNNSDLASFKEAKNLSIANFKSISK-LNESLVNLNKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIER---TSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV-----------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
M + N S L F AK F+ + + ES L ++ + + + E + K I +L R+ MK FFGRTSNGKSSVIN+ML K+LP GIGHTT+CF++++GT F+ + +G++ + + +V L+HAL D+ + + SL+ + WP C LL+ ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK+FFHKV +LS PNIFILNNRWDA E + + ++QH RC FL EL V +A +RIFFVSAKE+L+ R + L R F FER E+ + SA+KTKF H+++ ++ E + I+ ++ Q ++ K + D I + + +I + + + + + ++ EI+ L+ +V F F P + +YK EL+ H+E+ + ++ C+ AI + + +ID LL + + ++ R + +DL C+ + S+F+ED++F + L ++ N L R ++ +D V Q Q +M + ++ ++ +G + +I K G+R+I S+ YGLLY+YER+ W+ +E+ FK Q+V YAS +L ++ N S ++Q+L
Sbjct: 21 MAEVNASPLKHFVTAKKKINGIFEQLGAYIKESSAFLEETYSNEELDPVTTEEQVAEVRGYLSKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNEAFL--------------LTEGSE-ERKNVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMEEVRRQHMDRCSSFLVDELGVVDRAQASDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQISEALRLIMDSVHVAAQEQRIHCMETKEEREDRLDFIDKQLDLLTLDCKSKIRKITEEVEKQVSNAMAEEIRRLHVLVDEFHLDFHPSQVVLKVYKNELHRHIEEGLGRNMSERCSNAITSALQNTQTEMIDGLKPLLPLSVREQVDKMVPRQCFSLSYDLN--CDKLCSDFQEDINFHFSLG-WTMLVNRFLGPKNTRRALMGYNDQVPRPMAITPVSTSMPPFQQGSMTQEELMVSMVTGLASL-TSRTSMGIIVVGGVIWKAVGWRLIALSVGLYGLLYVYERLTWTTRAKERAFKRQFVDYASEKLQLIVSYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Match: EDO42379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L1]) HSP 1 Score: 326.635 bits (836), Expect = 1.523e-100 Identity = 226/709 (31.88%), Postives = 359/709 (50.63%), Query Frame = 2
Query: 128 KSISKLNESLVNLNKSLTEY-----------DANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXX---XXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL------DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTS-EHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNP--DDNVQSLRRQLNVMRP---------FLNSFKNI--FVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDI 2152
K+ K+NE++ + K L E D +N G D+ + I ++ R +MK AFFGRTSNGKS+V+N+ML +ILP GIGHTT+CF+ + G+ + +I+ + + + N K ++ ++HAL +K+ SL+ +YWP C++L +V +DSPG+D+ PDLD WI+ +CLDADVFVLV NAESTL TEK FFHKV KLSKPNIFILNNRWDA E + + KKQH QR +DFL+KEL+ ++A +R+FFVSAKE L R ++ + R F FE E+ + SA++TKF SH+ G+ +V + NIL ++ + + K + + + +K + ++I + I + +++ EI L +V F PF P + YK EL+ ++EK + + C+ + I ++ +ID+ KLL + +S++ + R E + + + S+FKED+ F + L ++ L AR ++ P D + + R + P L + ++ L+ +V G+R+I YG LY+ ER+RW+ S +EK FK Q+V +AS +L V+ + N ++Q+L + + ++EI + E+EI L I
Sbjct: 34 KAKKKINETVSEIGKYLDEANRFICGCEIAEDYKSNIKGFACDVAGFLGQ-VASITEVIARDQMKVAFFGRTSNGKSTVVNAMLQDRILPMGIGHTTNCFLSVNGSDSADPYILIPE--SDERRNVK-------------TLGQIAHALFEEKLDHSSLVQVYWPKSRCKMLSEDVVLVDSPGIDVSPDLDLWIDKHCLDADVFVLVCNAESTLMVTEKNFFHKVNQKLSKPNIFILNNRWDASAGEPDVEMMELVKKQHLQRNVDFLSKELKCVDKKQAEDRVFFVSAKETLMSRMQKHQGMPEEGGAIHVDGFHGRKLEFENFEHKFEECISKSAIQTKFESHAGTGIGIVNAVQNILEQIAGCAYEHRKRLISAKRERENRLEFVKEQLDYCTNECKEKIKHLSTRIEQQVADAMTEEIGRLGVLVNEFEHPFHTHPGFLRTYKKELHEYIEKGLGRNLMARCSSSQTQLIQETQQDMIDRLQKLLPCDEPQSVLPLTPRQDFEVCYQLEIHNLCSDFKEDIEFHFSLGWEALVKR-FLAPRNARLAILVPSTDHHRELEPRPAGPVMPRCSYSDEEMTLAVIHGVASLTSRTATVVVLAGGLLWRVMGWRIIICCTGLYGGLYVIERLRWTNSAKEKTFKRQFVDFASEKLQLVVSFTSSNCGLQVQQELSSTFSRLQSLVHRSKENLEDEILELEAEITRLESI 725
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009]) HSP 1 Score: 354.755 bits (909), Expect = 9.739e-111 Identity = 239/760 (31.45%), Postives = 398/760 (52.37%), Query Frame = 2
Query: 68 KNNSDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTEY--DANANFLGE------YQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXX-XXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIE-RTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNAL----------LLSYEARN-------------SMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
+ +S F K+ +A K IS + E L+N K +E+ D + N E + I + +K I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT D ++ K + SD + I +V ++HAL D+ + + L+ ++WP C LL+ ++ +DSPG D+ LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRWDA + + + +KQH RC++FL +EL+V E+A RIFF+SAKE+L R L +R + F FER E+ + SA+KTKF H+++ ++ E + +I+ ++ + A++ + ++ + +KN + + I K+I + +++ K + ++ EI L+ IV F + F P P + IYK++L +HVE+ M +A C A+ + +K +I+ LL + ++ RT + + C+T+ S+F+ED+ F++ L ++ L L+ +R+ S+ P +N +L Q +M N+ ++ ++ + ++ K G+R+I S YG+LYLYER+ W+ +E+ K Q+V YA+ +L ++ + N S ++Q++ + +D + +IR+ +I + + + S E++R L EF ++YL
Sbjct: 9 RTDSSRGEFSPLKHFVVAK-KKISDVFEQLLNYVKETSEFVEDISGNTALENVATPDQKSEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYL---KTEGSD------------EEKSIKTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPETGGALAEGFQERLKEFQSFERRFEECISQSAVKTKFEQHTIRAKQITEKVKSIMDDIHIEAAEKRVAALEARENQTDRLEFVKNQLNLLIAEIKKKIKAISEDVESKVSIAMGEEICRLHVIVDEFHADFHPSPQVLKIYKSDLLSHVEEGMGKNLAFRCTNAVNASVQSTQKYMIESMQPLLPAAAQSQICMLVPNRTLDLSYDLNCSTLCSDFQEDIEFRFSLGWQALVHRFLGSVNAQRALKLVDQTSRSALPVAQTPSSGPPSIAAPANNEAALMSQEELMIALANNVASL-TSRTSMTVIIAGGVVWKTVGWRLIALSASLYGVLYLYERLTWTTKAKERALKRQFVDYATEKLQLIVSFTSANCSHQVQQEMATTFARLCQQVDQTQKELEADIRQLTDKIDQMEKVQSRSKSLRHKATELERQLEEFTQQYL 751
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009]) HSP 1 Score: 340.502 bits (872), Expect = 2.923e-105 Identity = 234/750 (31.20%), Postives = 387/750 (51.60%), Query Frame = 2
Query: 68 KNNSDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTEYDANANFLGEYQDM--------INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXX-XXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRV----EIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIE-RTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNAL----------LLSYEARN-------------SMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGL 2188
+ +S F K+ +A K IS + E L+N K +E+ F +++ I + +K I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT D ++ K + SD + I +V ++HAL D+ + + L+ ++WP C LL+ ++ +DSPG D+ LD WI+ CLDADVFVLVAN+ESTL TEK FFHKV +LSKPNIFILNNRWDA + + + +KQH RC++FL +EL+V E+A RIFF+SAKE+L R L +R + F FER E+ + SA+KTKF H+++ ++ E + +I+ ++ + A++ + ++ + +KN + + I K+I + + TES+ + EI L+ IV F + F P P + IYK++L +HVE+ M +A C A+ + +K +I+ LL + ++ RT + + C+T+ S+F+ED+ F++ L ++ L L+ +R+ S+ P +N +L Q +M N+ ++ ++ + ++ K G+R+I S YG+LYLYER+ W+ +E+ K Q+V YA+ +L ++ + N S ++Q++ + +D + +IR+ +I + + + S V L
Sbjct: 9 RTDSSRGEFSPLKHFVVAK-KKISDVFEQLLNYVKETSEFVEGGRFPESLENVATPDQKSEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYL---KTEGSD------------EEKSIKTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPETGGALAEGFQERLKEFQSFERRFEECISQSAVKTKFEQHTIRAKQITEKVKSIMDDIHIEAAEKRVAALEARENQTDRLEFVKNQLNLLIAEIKKKIKAI------RFTESVSIAMGEEICRLHVIVDEFHADFHPSPQVLKIYKSDLLSHVEEGMGKNLAFRCTNAVNASVQSTQKYMIESMQPLLPAAAQSQICMLVPNRTLDLSYDLNCSTLCSDFQEDIEFRFSLGWQALVHRFLGSVNAQRALKLVDQTSRSALPVAQTPSSGPPSIAAPANNEAALMSQEELMIALANNVASL-TSRTSMTVIIAGGVVWKTVGWRLIALSASLYGVLYLYERLTWTTKAKERALKRQFVDYATEKLQLIVSFTSANCSHQVQQEMATTFARLCQQVDQTQKELEADIRQLTDKIDQMEKVQSRSKSLRSVQL 735
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn2 (mitofusin 2 [Source:NCBI gene;Acc:101170481]) HSP 1 Score: 321.242 bits (822), Expect = 5.521e-98 Identity = 225/701 (32.10%), Postives = 358/701 (51.07%), Query Frame = 2
Query: 44 AIFH-----KMTDKNNSDLASFKEAKNLSIANFKSISK-LNESLVNLNKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIER---TSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNV-----------------QSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDL 2047
A FH M + N S L F AK F+ + + ES L + D + E + K I +L R+ MK FFGRTSNGKS+VIN+ML K+LP GIGHTT+CF++++GT + GF+ + +G++ + I +V L+HAL D+ + + SL+ + WP C LL+ ++ +DSPG+D+ +LD WI+ CLDADVFVLVAN+ESTL QTEK+FFHKV +LS PNIFILNNRWDA E + + ++QH RC +FL +EL V +A +RIFFVSAKE+L+ R L R F FER E+ + SA+KTKF H+++ ++ E + I+ ++ Q ++ K + I + + +I + + + + + ++ EI+ L +V +F F P + +YK EL+ H+E+ + ++ C+ +I + + +I+ LL + + ++ R + +DL C+ + S+F+ED+SF + L ++ N L R ++ D V QS Q +M + ++ ++ +G + +I K G+R+I SL YGLLY+YER+ W+ +E+ FK Q+V YAS +L ++ N S ++Q+L
Sbjct: 11 APFHCKEKRTMAEVNASPLKHFVTAKKKINGIFEQLGAYIRESASFLEDAHRNEDLDPVTAEEQVQEVRGFLSKVAGIGEVLARRHMKVVFFGRTSNGKSTVINAMLCDKVLPSGIGHTTNCFLRVEGTDGSEGFL--------------LTEGSE-EKKSIKTVNQLAHALHQDQDLDAGSLVCVMWPKVKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMDEVRRQHMDRCSNFLVEELGVVDRAQASDRIFFVSAKEVLQARMQRVQGMPEAGGALAEGFQARMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQISEALRRIMDSVHVAAQEQRVYCLETKEDRQDRLEFIDKQLDLLTTDCKSKIKKITEEVERQVSNAMAEEIRKLYVLVDDFHMDFHPSAVVLKVYKNELHRHIEEGLGKNMSERCSSSISSALQATQADMIEGLKPLLPSTLRDQVEKMVPRQCFSLTYDLA--CDKLCSDFQEDISFHFSLG-WTMLVNRFLGPKNTRRALMGYSDQVPRPMALTPVSSSMPPFPQSAMTQEELMVSMVTGLASL-TSRTSMGVLVVGGVIWKAVGWRLIALSLGLYGLLYVYERLTWTTKAKERAFKRQFVDYASEKLQLIVSYTGSNCSHQVQQEL 692
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000009003.2 (pep primary_assembly:ASM223467v1:17:11595384:11602171:-1 gene:ENSORLG00000007178.2 transcript:ENSORLT00000009003.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 230.72 bits (587), Expect = 6.903e-69 Identity = 123/284 (43.31%), Postives = 166/284 (58.45%), Query Frame = 2
Query: 227 INSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDK-VSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRW-XXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVL-----DRYENFLQFERSLE 1057
+ S K I +L R+ MK AFFGRTSNGKS+VIN+ML ++LP GIGHTT+CF+ ++GT ++ ++ + I +V L+HAL D + S L+ ++WP C LL+ ++ +DSPG D+ +LD WI+ CLDADVFVLV NAESTL TEK FFHKV ++SKPNIFIL+NRW + + D + +KQH RC+ FL +EL V EA RIFF+SAKE+L R L +R F +FER+ E
Sbjct: 56 MQSCATKLYTIRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDGDEAYLTSEASE---------------ERRSISTVNQLAHALHMDPTLDSSCLVKVFWPKSRCALLRNDLVLMDSPGTDVTLELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQEVRKQHLDRCVGFLAEELGVVGPNEAPGRIFFISAKEVLSSRMQRAQGMPETGGALAEGFHERLTEFQRFERTFE 324
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000041052.1 (pep primary_assembly:ASM223467v1:17:11590174:11596131:-1 gene:ENSORLG00000029782.1 transcript:ENSORLT00000041052.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.1814 bits (191), Expect = 2.347e-15 Identity = 61/269 (22.68%), Postives = 134/269 (49.81%), Query Frame = 2
Query: 1223 DKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSL-----RRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCT 2014
D ++ +++ + I ++I I+ D + K +L I+ L +V+ F + F P + +YKA+L H++ ++ +A+ C+ + +I ++ + D LL + + + V + E + + ++F+E++ FQ+ L ++ + + + AR ++ D Q ++V + +++ ++ + I ++ + G+RVI S YGLLYLYER+ W+ + +E+ K Q+V++A++ L VI V +
Sbjct: 27 DFVRGQMNRLTNGIKERIQILSDEVTAKVASALSDHIRLLPVLVEEFRADFKPTKETLELYKAKLVQHLQDQLLASLAHRCSAGVHRDIKDAQRHMTDSVRPLLSSSV-QDQLSVPYTSFELTYDLGLAALCADFQENIDFQFSLGWTALVTR-FIGAANARRALRGLDSKSQEGSVFKDEMMVSVAKRLVSA-----TSRASMTVLVIGGVVWRSVGWRVIALSFSLYGLLYLYERLTWTDASRERALKQQFVQHAAHSLGAVIPVTS 288
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000034875.1 (SMESG000034875.1) HSP 1 Score: 1431.77 bits (3705), Expect = 0.000e+0 Identity = 722/724 (99.72%), Postives = 723/724 (99.86%), Query Frame = 2
Query: 59 MTDKNNSDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLDRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
MTDKNNSDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKT DLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWDACDDEDDVVAAKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLDRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITSSLCSYG+LYLYERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL
Sbjct: 1 MTDKNNSDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTEYDANANFLGEYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTPDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWDACDDEDDVVAAKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLDRYENFLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLTIPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNNPDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITSSLCSYGVLYLYERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 724
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000000387.1 (SMESG000000387.1) HSP 1 Score: 412.149 bits (1058), Expect = 5.940e-133 Identity = 263/749 (35.11%), Postives = 413/749 (55.14%), Query Frame = 2
Query: 77 SDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTE-YDANANFLGEYQDMINSTN--------EKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFIVKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXX-XXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNN----------PKVLDRYEN----FLQFERSLEKNLCASALKTKFASHSLQGLELVEIMLNILHKLNDQIQLNLNVAVDKKLKESHIRDKIKNGNSKVNDNIVKQISIVLDNIIMKTTESLRVEIKHLNYIVKNFTSPFDPDPAHMHIYKAELNNHVEKEMNNRIANFCAGAIRYEIMMYKKCLIDQYTKLLGYEIDRSMIDVIERTSEHDLT----IPCNTIFSNFKEDLSFQWPLNPHSVFSNALLLSYEARNSMNN---PDDNVQSLRRQLNVMRPFLNSFKNIFVNKEFVGFCFISALICKVTGFRVITXXXXXXXXXXXXERIRWSRSIQEKNFKNQYVKYASNQLTNVIDVCTRNYSCVIKQDLLMGHKSMGFFIDGQLGRYDNEIRKYESEIIYLTDILKSTNSANGVGLEIKRNLVEFQEKYL 2230
S L+ FKE+K I F I+ +++ N E Y+++A F Q +IN N +K I +++ R MKCAFFGRTSNGKS+ IN+MLG KILP GIGHTTSCF++IQGT D GFI K S N + +D+ PI SV DL+ +S +K+SS+SLI ++WP++ C LL +V LDSPG+D+DPD+D WI+ CLDADVFVLVAN+ESTL TEK+FFH V NKLSKPNIFILNNRWDA D+ + V ++QH ++C+ FL+KEL+VC+ EA R+FFVSA E L R+ + + PK+ + +++ F FE++LEK L SA KTKFA+HS+QG E+V + I+ LN++ Q + AV K +K+ + ++ +I + + + + + LR E++ L ++ +F F + + YK EL+ HVEK++ N + + A + ++ + ++ +Y LG D+ + + +++ +D + CN I S+F+EDL+F++ L P ++ + R+ P L + MR L S + + LI + TG++V+ + C YG +Y YE W+ +EK FK Q+ Y + +L V+ ++N + + L +S+ +D + + ++ K+E ++ L DI+ + S + +++ L F +KY+
Sbjct: 11 SQLSIFKESKTEIIKIFHDIAIY---VMDSNTFFNEIYNSDAMF----QSLINVDNVKLLVNFVDKVNGIQNVISRNNMKCAFFGRTSNGKSTTINAMLGGKILPTGIGHTTSCFLEIQGTDDNQGFI-----KISSPENINDESADVVDSKPIDSVKDLARDVSLNKLSSDSLIKIFWPNEKCPLLSQDVVILDSPGIDVDPDIDKWIDMYCLDADVFVLVANSESTLNHTEKSFFHNVSNKLSKPNIFILNNRWDASADQVEYVKEVREQHTEKCVAFLSKELKVCSKTEAESRVFFVSASEALNMRSRKAESSGGDSIAAGESPSLPKMREGWQSRLFEFTNFEKNLEKTLSESATKTKFAAHSVQGQEIVTEVRLIVEGLNEKAQEQKDAAVTLTHKMRARSEKLDSHRKAAHNESCIEIKRLSEKVAERVADVLREELRRLGDVIDDFDHTFYEESGLLSKYKVELSQHVEKQLGNNLTSILARDLCAQVELVNGSILKKY---LGLIQDKETGEKMRKSAYNDYAPQFYVDCNNISSDFREDLTFRFSLGPTALLGKLIGPIAPGRHPTGGFSIPSGTSGLL--SMLAMRQVLPS----ITGRSVLVTVLCGGLILRATGWKVLGAVACIYGAVYGYEYSTWTTRAKEKAFKLQFRSYVAEKLELVMAYTSKNSADQPQNSLTRSLRSLDGVVDKHINKLKEDVTKFEKDVKRLEDIVTKSRSMKNKAIYLEKVLKNFHDKYI 738
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000013693.1 (SMESG000013693.1) HSP 1 Score: 142.51 bits (358), Expect = 5.410e-39 Identity = 73/169 (43.20%), Postives = 105/169 (62.13%), Query Frame = 2
Query: 275 RKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFI----VKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKV 769
R +KC F GRTSNGKS+VINS+L + LP G+GHTT+C + I+ + + FI KN+ K + + + + + + +HALS DK +S+ I + +P +C ++K V +DSPG+DI+ D D WI CLDAD+FV+V+NAES L Q EK FFHK+
Sbjct: 2 RNYLKCVFIGRTSNGKSTVINSVLKKTDLPMGLGHTTNCCILIRCSEKHDPFIEHFTAKNQQKPASIYS-------------LDKLKNFAHALSKDKFNSDETIQVNYPIDSCPIIKTNVYLVDSPGIDIETDFDIWIEKYCLDADLFVMVSNAESILMQCEKNFFHKM 157
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1) HSP 1 Score: 127.487 bits (319), Expect = 2.733e-30 Identity = 90/288 (31.25%), Postives = 145/288 (50.35%), Query Frame = 2
Query: 212 EYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFI-VKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLDRYENFLQFERSLEKNLCA 1072
+YQ + N +E+ + I+ RK KC FG+TS+GKSS+IN++L ++ILP G T++ FVQI+ +S +I + N+ KT I S+ +L+ L + S + L++ + C LLK + +D+PG+D D D + D ++ +LV N+ S ++ EK F K K SK ++ I+ N WD D + A +KQ+ + LT EL ++E RIFF+SA E +S+ +P R +F QF +L+ L
Sbjct: 42 KYQSIYN-FDEQAADLKRIIHRKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKT------------------IESLRELTSLLCEGHIKDGSHVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGY-SNENVSNRIFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELAT 309
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1) HSP 1 Score: 127.102 bits (318), Expect = 6.382e-30 Identity = 90/288 (31.25%), Postives = 145/288 (50.35%), Query Frame = 2
Query: 212 EYQDMINSTNEKCERIISILERKKMKCAFFGRTSNGKSSVINSMLGQKILPYGIGHTTSCFVQIQGTSDTNGFI-VKNKNKTSDLNNCKMDDGTQIDNLPIHSVMDLSHALSTDKVSSESLILLYWPHQNCELLKAEVTFLDSPGVDIDPDLDYWINHNCLDADVFVLVANAESTLTQTEKAFFHKVKNKLSKPNIFILNNRWXXXXXXXXXXXXKKQHQQRCIDFLTKELQVCTHEEACERIFFVSAKEMLEFRTSENSYRSNNPKVLDRYENFLQFERSLEKNLCA 1072
+YQ + N +E+ + I+ RK KC FG+TS+GKSS+IN++L ++ILP G T++ FVQI+ +S +I + N+ KT I S+ +L+ L + S + L++ + C LLK + +D+PG+D D D + D ++ +LV N+ S ++ EK F K K SK ++ I+ N WD D + A +KQ+ + LT EL ++E RIFF+SA E +S+ +P R +F QF +L+ L
Sbjct: 42 KYQSIYN-FDEQAADLKRIIHRKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKT------------------IESLRELTSLLCEGHIKDGSHVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGY-SNENVSNRIFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELAT 309 The following BLAST results are available for this feature:
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30016209 ID=SMED30016209|Name=Dynamin-type G domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2302bpback to top protein sequence of SMED30016209-orf-1 >SMED30016209-orf-1 ID=SMED30016209-orf-1|Name=SMED30016209-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=725bp MTDKNNSDLASFKEAKNLSIANFKSISKLNESLVNLNKSLTEYDANANFLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
