V-type proton ATPase proteolipid subunit

Overview


Name	V-type proton ATPase proteolipid subunit
Smed ID	SMED30016201
Length (bp)	917

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of V-type proton ATPase proteolipid subunit (SMED30016201) t-SNE clustered cells

Violin plots show distribution of expression levels for V-type proton ATPase proteolipid subunit (SMED30016201) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of V-type proton ATPase proteolipid subunit (SMED30016201) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for V-type proton ATPase proteolipid subunit (SMED30016201) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016201

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 16

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30016201	SMESG000038824.1	Contig429	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30016201	SMESG000068628.1	Contig429	GPL15192	PMID:23079596 Forsthoefel et al., 2012
nervous system	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30016201	SMESG000068628.1	dd_Smed_v4_253_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016201	SMESG000068628.1	Contig20062	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016201	SMESG000068628.1	Contig20062	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016201	SMESG000068628.1	Contig49505	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016201	SMESG000068628.1	Contig49505	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
intestinal phagocyte	SMED30016201	SMESG000068628.1	dd_Smed_v6_253_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30016201	SMESG000068628.1	dd_Smed_v6_253_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Human
Match: ATP6V0C (ATPase H+ transporting V0 subunit c [Source:HGNC Symbol;Acc:HGNC:855])

HSP 1 Score: 197.208 bits (500), Expect = 8.170e-63
Identity = 125/150 (83.33%), Postives = 132/150 (88.00%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            S P Y  FF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPE IMKSIIPVVMAGIIAIYGLVVAVLIA  L+  + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    6 SGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Human
Match: ATP6V0C (ATPase H+ transporting V0 subunit c [Source:HGNC Symbol;Acc:HGNC:855])

HSP 1 Score: 142.51 bits (358), Expect = 3.862e-42
Identity = 97/112 (86.61%), Postives = 101/112 (90.18%), Query Frame = 2

Query:  194 MAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            M+VMRPE IMKSIIPVVMAGIIAIYGLVVAVLIA  L+  + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 112

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Human
Match: ATP6V0C (ATPase H+ transporting V0 subunit c [Source:HGNC Symbol;Acc:HGNC:855])

HSP 1 Score: 142.51 bits (358), Expect = 3.862e-42
Identity = 97/112 (86.61%), Postives = 101/112 (90.18%), Query Frame = 2

Query:  194 MAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            M+VMRPE IMKSIIPVVMAGIIAIYGLVVAVLIA  L+  + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 112

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Celegans
Match: vha-3 (V-type proton ATPase 16 kDa proteolipid subunit 2/3 [Source:RefSeq peptide;Acc:NP_500188])

HSP 1 Score: 171.014 bits (432), Expect = 6.418e-53
Identity = 104/149 (69.80%), Postives = 118/149 (79.19%), Query Frame = 2

Query:   92 YTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSS---LKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            Y PFFG MG  SA +F  LGAAYGTAKS  GI SM VMRPELIMKS+IPV+MAGII IYGLVVA+++  K+ S+     +     +L AGL+ GL GL AG+AIGIVGDAGVRGTAQQPRLFVGMILILIF+EVLGLYG+IVALIL T 
Sbjct:   13 YAPFFGYMGAASAQIFTVLGAAYGTAKSAVGICSMGVMRPELIMKSVIPVIMAGIIGIYGLVVAMVLKGKVTSASAGYDLNKGFAHLAAGLTCGLCGLGAGYAIGIVGDAGVRGTAQQPRLFVGMILILIFSEVLGLYGMIVALILGTS 161

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Query:   92 YTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSS---LKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            Y PFFG MG  SA +F  LGAAYGTAKS  GI SM VMRPELIMKS+IPV+MAGII IYGLVVA+++  K+ S+     +     +L AGL+ GL GL AG+AIGIVGDAGVRGTAQQPRLFVGMILILIF+EVLGLYG+IVALIL T 
Sbjct:   13 YAPFFGYMGAASAQIFTVLGAAYGTAKSAVGICSMGVMRPELIMKSVIPVIMAGIIGIYGLVVAMVLKGKVTSASAGYDLNKGFAHLAAGLTCGLCGLGAGYAIGIVGDAGVRGTAQQPRLFVGMILILIFSEVLGLYGMIVALILGTS 161

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Celegans
Match: vha-2 (V-type proton ATPase 16 kDa proteolipid subunit 2 [Source:UniProtKB/Swiss-Prot;Acc:C0HLB3])

HSP 1 Score: 171.014 bits (432), Expect = 6.418e-53
Identity = 104/149 (69.80%), Postives = 118/149 (79.19%), Query Frame = 2

Query:   92 YTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSS---LKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            Y PFFG MG  SA +F  LGAAYGTAKS  GI SM VMRPELIMKS+IPV+MAGII IYGLVVA+++  K+ S+     +     +L AGL+ GL GL AG+AIGIVGDAGVRGTAQQPRLFVGMILILIF+EVLGLYG+IVALIL T 
Sbjct:   13 YAPFFGYMGAASAQIFTVLGAAYGTAKSAVGICSMGVMRPELIMKSVIPVIMAGIIGIYGLVVAMVLKGKVTSASAGYDLNKGFAHLAAGLTCGLCGLGAGYAIGIVGDAGVRGTAQQPRLFVGMILILIFSEVLGLYGMIVALILGTS 161

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Celegans
Match: vha-1 (V-type proton ATPase 16 kDa proteolipid subunit 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21898])

HSP 1 Score: 157.918 bits (398), Expect = 9.971e-48
Identity = 101/154 (65.58%), Postives = 125/154 (81.17%), Query Frame = 2

Query:   68 ILQMSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLD---SSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALIL 520
            +L+  + +Y PFFG +GVTSAM F A G+AYGTAK+GTGIASMAV RP+L+MK+IIPVVMAGI+AIYGLVVAV+++ K++   ++  + N+      GL  GL GL AG+AIGI GDAGVR  +QQPR+FVGMILILIFAEVLGLYG+IVALIL
Sbjct:   13 LLKNEQAMYGPFFGSLGVTSAMAFAAAGSAYGTAKAGTGIASMAVARPDLVMKAIIPVVMAGIVAIYGLVVAVIVSGKVEPAGANYTINNAFSQFAGGLVCGLCGLGAGYAIGIAGDAGVRALSQQPRMFVGMILILIFAEVLGLYGMIVALIL 166

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Query:   68 ILQMSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLD---SSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALIL 520
            +L+  + +Y PFFG +GVTSAM F A G+AYGTAK+GTGIASMAV RP+L+MK+IIPVVMAGI+AIYGLVVAV+++ K++   ++  + N+      GL  GL GL AG+AIGI GDAGVR  +QQPR+FVGMILILIFAEVLGLYG+IVALIL
Sbjct:   13 LLKNEQAMYGPFFGSLGVTSAMAFAAAGSAYGTAKAGTGIASMAVARPDLVMKAIIPVVMAGIVAIYGLVVAVIVSGKVEPAGANYTINNAFSQFAGGLVCGLCGLGAGYAIGIAGDAGVRALSQQPRMFVGMILILIFAEVLGLYGMIVALIL 166

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Fly
Match: Vha16-1 (gene:FBgn0262736 transcript:FBtr0086153)

HSP 1 Score: 191.815 bits (486), Expect = 6.228e-61
Identity = 122/152 (80.26%), Postives = 131/152 (86.18%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLD--SSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
              PIY PFFGVMG  SA++F ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L+  S   +     +LGAGL+VG SGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVA+ L TK
Sbjct:    8 DNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK 159

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Fly
Match: Vha16-1 (gene:FBgn0262736 transcript:FBtr0086152)

HSP 1 Score: 191.815 bits (486), Expect = 6.228e-61
Identity = 122/152 (80.26%), Postives = 131/152 (86.18%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLD--SSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
              PIY PFFGVMG  SA++F ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L+  S   +     +LGAGL+VG SGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVA+ L TK
Sbjct:    8 DNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK 159

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Fly
Match: Vha16-1 (gene:FBgn0262736 transcript:FBtr0086151)

HSP 1 Score: 191.815 bits (486), Expect = 6.228e-61
Identity = 122/152 (80.26%), Postives = 131/152 (86.18%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLD--SSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
              PIY PFFGVMG  SA++F ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L+  S   +     +LGAGL+VG SGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVA+ L TK
Sbjct:    8 DNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK 159

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Fly
Match: Vha16-1 (gene:FBgn0262736 transcript:FBtr0086150)

HSP 1 Score: 191.815 bits (486), Expect = 6.228e-61
Identity = 122/152 (80.26%), Postives = 131/152 (86.18%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLD--SSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
              PIY PFFGVMG  SA++F ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L+  S   +     +LGAGL+VG SGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVA+ L TK
Sbjct:    8 DNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK 159

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Fly
Match: Vha16-3 (gene:FBgn0028667 transcript:FBtr0076090)

HSP 1 Score: 190.274 bits (482), Expect = 1.947e-60
Identity = 118/150 (78.67%), Postives = 128/150 (85.33%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
             +P Y+ FFG MG  SA++F ALGAAYGTAKSGTGIA+MAVMRPELIMKSIIPVVMAGIIAIYGLVV+VLIA  L  S  +     +L AGLSVG +GLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVA+ L TK
Sbjct:    9 DKPAYSFFFGSMGAASAIIFSALGAAYGTAKSGTGIAAMAVMRPELIMKSIIPVVMAGIIAIYGLVVSVLIAGSLSDSYTIRKGYIHLAAGLSVGFAGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK 158

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Zebrafish
Match: atp6v0ca (ATPase H+ transporting V0 subunit ca [Source:ZFIN;Acc:ZDB-GENE-020419-23])

HSP 1 Score: 204.142 bits (518), Expect = 9.520e-66
Identity = 126/153 (82.35%), Postives = 135/153 (88.24%), Query Frame = 2

Query:   71 LQMSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +    P Y+PFF VMG +SAMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +   + +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MDTQNPQYSPFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNIGDKISLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 153

[Close]

Query:   71 LQMSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +    P Y+PFF VMG +SAMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +   + +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MDTQNPQYSPFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNIGDKISLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 153

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Zebrafish
Match: atp6v0cb (ATPase H+ transporting V0 subunit cb [Source:ZFIN;Acc:ZDB-GENE-030131-4127])

HSP 1 Score: 202.601 bits (514), Expect = 3.997e-65
Identity = 125/149 (83.89%), Postives = 134/149 (89.93%), Query Frame = 2

Query:   83 EPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
             P Y+PFF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +   + +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    5 SPEYSPFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSISDKITLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 153

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Zebrafish
Match: atp6v0b (ATPase H+ transporting V0 subunit b [Source:ZFIN;Acc:ZDB-GENE-030131-443])

HSP 1 Score: 53.5286 bits (127), Expect = 4.360e-8
Identity = 47/156 (30.13%), Postives = 85/156 (54.49%), Query Frame = 2

Query:   95 TPF-FGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDS----------SLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +PF +  +G+  A+    +GAA+G   +G+ I    V  P +  K+++ ++    +AIYG+++A++I+   ++          S   +      GAGL+VG S L  G  +GIVG       AQ   LFV ++++ IF   +GL+G+IVA++ ++K
Sbjct:   46 SPFMWANLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNLAENFSGTTPETIGSKNYQAGYSMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNANLFVRILIVEIFGSAIGLFGVIVAILQTSK 201

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Xenopus
Match: atp6v0c (ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c [Source:NCBI gene;Acc:394488])

HSP 1 Score: 204.142 bits (518), Expect = 1.191e-65
Identity = 129/150 (86.00%), Postives = 135/150 (90.00%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            S P Y+ FF VMG +SAMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L SS+ +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    7 SAPEYSAFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTSSITLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 156

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Xenopus
Match: atp6v0c (ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c [Source:NCBI gene;Acc:394488])

HSP 1 Score: 201.83 bits (512), Expect = 9.703e-65
Identity = 128/150 (85.33%), Postives = 135/150 (90.00%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            + P Y+ FF VMG +SAMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L SS+ +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    7 NAPEYSAFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTSSITLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 156

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Xenopus
Match: atp6v0b (ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b [Source:NCBI gene;Acc:549818])

HSP 1 Score: 55.0694 bits (131), Expect = 2.118e-8
Identity = 44/138 (31.88%), Postives = 75/138 (54.35%), Query Frame = 2

Query:  146 LGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDS----------SLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +GAA+G   +G+ I    V  P +  K+++ ++    +AIYG+++A++I+   +           S          GAGL+VG S L  G  +GIVG       AQ P LFV ++++ IF   +GL+G+IVA++ ++K
Sbjct:   63 VGAAWGIYITGSSILGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEQFKGTTPEAIGSRNYHAGFSMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSK 200

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Xenopus
Match: atp6v0b (ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b [Source:NCBI gene;Acc:549818])

HSP 1 Score: 51.9878 bits (123), Expect = 2.553e-7
Identity = 43/134 (32.09%), Postives = 72/134 (53.73%), Query Frame = 2

Query:  146 LGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDS----------SLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALI 517
            +GAA+G   +G+ I    V  P +  K+++ ++    +AIYG+++A++I+   +           S          GAGL+VG S L  G  +GIVG       AQ P LFV ++++ IF   +GL+G+IVA++
Sbjct:   64 VGAAWGIYITGSSILGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEQFKGTTPEAIGSRNYHAGFSMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAIL 197

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Mouse
Match: Atp6v0c (ATPase, H+ transporting, lysosomal V0 subunit C [Source:MGI Symbol;Acc:MGI:88116])

HSP 1 Score: 201.06 bits (510), Expect = 1.473e-64
Identity = 126/150 (84.00%), Postives = 134/150 (89.33%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            + P Y+ FFGVMG +SAMVF A+GAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L   + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    6 NNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155

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Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            + P Y+ FFGVMG +SAMVF A+GAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L   + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    6 NNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Mouse
Match: Atp6v0c (ATPase, H+ transporting, lysosomal V0 subunit C [Source:MGI Symbol;Acc:MGI:88116])

HSP 1 Score: 191.43 bits (485), Expect = 8.025e-61
Identity = 121/145 (83.45%), Postives = 129/145 (88.97%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAL 514
            + P Y+ FFGVMG +SAMVF A+GAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L   + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAL
Sbjct:    6 NNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAL 150

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BLAST of V-type proton ATPase proteolipid subunit vs. UniProt/SwissProt
Match: sp|P63081|VATL_RAT (V-type proton ATPase 16 kDa proteolipid subunit OS=Rattus norvegicus OX=10116 GN=Atp6v0c PE=2 SV=1)

HSP 1 Score: 201.06 bits (510), Expect = 1.030e-63
Identity = 126/150 (84.00%), Postives = 134/150 (89.33%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            + P Y+ FFGVMG +SAMVF A+GAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L   + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    6 NNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155

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BLAST of V-type proton ATPase proteolipid subunit vs. UniProt/SwissProt
Match: sp|P63082|VATL_MOUSE (V-type proton ATPase 16 kDa proteolipid subunit OS=Mus musculus OX=10090 GN=Atp6v0c PE=1 SV=1)

HSP 1 Score: 201.06 bits (510), Expect = 1.030e-63
Identity = 126/150 (84.00%), Postives = 134/150 (89.33%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            + P Y+ FFGVMG +SAMVF A+GAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L   + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    6 NNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155

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BLAST of V-type proton ATPase proteolipid subunit vs. UniProt/SwissProt
Match: sp|O18882|VATL_SHEEP (V-type proton ATPase 16 kDa proteolipid subunit OS=Ovis aries OX=9940 GN=ATP6V0C PE=2 SV=1)

HSP 1 Score: 198.749 bits (504), Expect = 1.113e-62
Identity = 125/150 (83.33%), Postives = 133/150 (88.67%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            S P Y  FF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPE+IMKSIIPVVMAGIIAIYGLVVAVLIA  L+  + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    6 SGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEMIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDGISLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155

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BLAST of V-type proton ATPase proteolipid subunit vs. UniProt/SwissProt
Match: sp|P23956|VATL_BOVIN (V-type proton ATPase 16 kDa proteolipid subunit OS=Bos taurus OX=9913 GN=ATP6V0C PE=1 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 2.541e-62
Identity = 127/155 (81.94%), Postives = 135/155 (87.10%), Query Frame = 2

Query:   77 MSE----PIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            MSE    P Y  FF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPE+IMKSIIPVVMAGIIAIYGLVVAVLIA  L+  + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MSEAKNGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEMIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDGISLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155

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BLAST of V-type proton ATPase proteolipid subunit vs. UniProt/SwissProt
Match: sp|Q03105|VATL_TORMA (V-type proton ATPase 16 kDa proteolipid subunit OS=Torpedo marmorata OX=7788 PE=1 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 3.445e-62
Identity = 125/148 (84.46%), Postives = 133/148 (89.86%), Query Frame = 2

Query:   86 PIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            P Y+ FFGV+G ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L   + +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    7 PEYSAFFGVIGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTEDISLFKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 154

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BLAST of V-type proton ATPase proteolipid subunit vs. TrEMBL
Match: A0A267DLB5 (V-type proton ATPase proteolipid subunit OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030187g1 PE=3 SV=1)

HSP 1 Score: 211.846 bits (538), Expect = 1.831e-65
Identity = 122/151 (80.79%), Postives = 141/151 (93.38%), Query Frame = 2

Query:   71 LQMSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILS 523
            + +++P+YTPFFGVMG ++AMVFCALGAAYGTAKSGTGIA+MAV+RPELIMKS++PVVMAGIIAIYGLVVAVLI+Q +     +E SL++LGAGL+VGLSGLA+G+AIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYG IVALILS
Sbjct:    1 MTINDPLYTPFFGVMGASAAMVFCALGAAYGTAKSGTGIANMAVLRPELIMKSVVPVVMAGIIAIYGLVVAVLISQNMTPDYTVEKSLRHLGAGLAVGLSGLASGYAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGFIVALILS 151

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BLAST of V-type proton ATPase proteolipid subunit vs. TrEMBL
Match: A0A448WK92 (V-type proton ATPase proteolipid subunit OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS7258 PE=3 SV=1)

HSP 1 Score: 211.46 bits (537), Expect = 4.343e-65
Identity = 132/149 (88.59%), Postives = 138/149 (92.62%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILST 526
            S+PIYTPFF VMG TS+MVFCALGAAYGTAKSG+GI SM VMRPELIMKSI+PVVMAGI+AIYGLVVAVLIAQ   S + ME SLK LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILST
Sbjct:   24 SDPIYTPFFSVMGATSSMVFCALGAAYGTAKSGSGICSMGVMRPELIMKSIVPVVMAGIVAIYGLVVAVLIAQSGQSKI-MEKSLKQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILST 171

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BLAST of V-type proton ATPase proteolipid subunit vs. TrEMBL
Match: A0A3B3XBH1 (V-type proton ATPase proteolipid subunit OS=Poecilia mexicana OX=48701 PE=3 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 1.071e-63
Identity = 126/151 (83.44%), Postives = 136/151 (90.07%), Query Frame = 2

Query:   77 MSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            MS P Y+PFF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +  ++ +  S  +L AGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MSSPEYSPFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNISDNISLYKSFCHLAAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 151

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BLAST of V-type proton ATPase proteolipid subunit vs. TrEMBL
Match: A0A3B3UP06 (V-type proton ATPase proteolipid subunit OS=Poecilia latipinna OX=48699 PE=3 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 1.071e-63
Identity = 126/151 (83.44%), Postives = 136/151 (90.07%), Query Frame = 2

Query:   77 MSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            MS P Y+PFF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +  ++ +  S  +L AGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MSSPEYSPFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNISDNISLYKSFCHLAAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 151

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BLAST of V-type proton ATPase proteolipid subunit vs. TrEMBL
Match: A0A1A7WUY8 (V-type proton ATPase proteolipid subunit (Fragment) OS=Iconisemion striatum OX=60296 GN=Nfu_g_1_022957 PE=3 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 1.619e-63
Identity = 127/152 (83.55%), Postives = 137/152 (90.13%), Query Frame = 2

Query:   74 QMSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +MS P Y+PFF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +   + +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    2 RMSSPEYSPFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNISDKITLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 153

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Cavefish
Match: atp6v0cb (V-type proton ATPase 16 kDa proteolipid subunit-like [Source:NCBI gene;Acc:103036123])

HSP 1 Score: 205.682 bits (522), Expect = 2.006e-66
Identity = 126/150 (84.00%), Postives = 137/150 (91.33%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            ++P+Y+PFF VMG +SAMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA    S + +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILST+
Sbjct:    5 AQPMYSPFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSTTSDVTLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTR 154

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Cavefish
Match: atp6v0ca (V-type proton ATPase 16 kDa proteolipid subunit [Source:NCBI gene;Acc:103027532])

HSP 1 Score: 202.601 bits (514), Expect = 3.616e-65
Identity = 125/153 (81.70%), Postives = 135/153 (88.24%), Query Frame = 2

Query:   71 LQMSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +    P Y+PFF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +   + +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MSAESPEYSPFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNISEKVTLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 153

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Cavefish
Match: atp6v0b (ATPase H+ transporting V0 subunit b [Source:NCBI gene;Acc:103033629])

HSP 1 Score: 53.5286 bits (127), Expect = 3.425e-8
Identity = 48/156 (30.77%), Postives = 85/156 (54.49%), Query Frame = 2

Query:   95 TPF-FGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDS----------SLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +PF +  +G+  A+    +GAA+G   +G+ I    V  P +  K++I ++    +AIYG+++A++I+   +S          +   +      GAGL+VG S L  G  +GIVG       AQ   LFV ++++ IF   +GL+G+IVA++ ++K
Sbjct:   46 SPFMWANLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLISIIFCEAVAIYGIIMAIVISNMAESFSGTTPETIGARNYQAGYSMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNGSLFVKILIVEIFGSAIGLFGIIVAILQTSK 201

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Sea Lamprey
Match: atp6v0ca (ATPase H+ transporting V0 subunit ca [Source:ZFIN;Acc:ZDB-GENE-020419-23])

HSP 1 Score: 182.57 bits (462), Expect = 2.644e-58
Identity = 117/133 (87.97%), Postives = 123/133 (92.48%), Query Frame = 2

Query:  131 MVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            MVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  L  ++ +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANGLTENITLFKSFMHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 133

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Yeast
Match: VMA3 (Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase; dicyclohexylcarbodiimide binding subunit; required for vacuolar acidification and important for copper and iron metal ion homeostasis [Source:SGD;Acc:S000000753])

HSP 1 Score: 169.088 bits (427), Expect = 6.289e-53
Identity = 106/156 (67.95%), Postives = 128/156 (82.05%), Query Frame = 2

Query:   77 MSE--PIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK*MQ 538
            M+E  P+Y PFFG +G  SA++F +LGAAYGTAKSG GI +  V+RP+L+ K+I+PV+MAGIIAIYGLVV+VL+   L     +      LGAGLSVGLSGLAAGFAIGIVGDAGVRG++QQPRLFVGMILILIFAEVLGLYGLIVAL+L+++  Q
Sbjct:    1 MTELCPVYAPFFGAIGCASAIIFTSLGAAYGTAKSGVGICATCVLRPDLLFKNIVPVIMAGIIAIYGLVVSVLVCYSLGQKQALYTGFIQLGAGLSVGLSGLAAGFAIGIVGDAGVRGSSQQPRLFVGMILILIFAEVLGLYGLIVALLLNSRATQ 156

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BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Yeast
Match: VMA11 (Vacuolar ATPase V0 domain subunit c'; involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen [Source:SGD;Acc:S000006155])

HSP 1 Score: 154.451 bits (389), Expect = 3.804e-47
Identity = 93/150 (62.00%), Postives = 113/150 (75.33%), Query Frame = 2

Query:   86 PIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLD--SSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            P+Y PFFG  G  +AMV   LGAA GTAKSG GIA +   +PELIMKS+IPVVM+GI+AIYGLVVAVLIA  L       + N   +L  GL VG + L++G+AIG+VGD GVR    QPRLFVG++LILIF+EVLGLYG+IVALIL+T+
Sbjct:   12 PLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTR 161

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Nematostella
Match: EDO45670 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS13])

HSP 1 Score: 196.438 bits (498), Expect = 3.223e-63
Identity = 124/150 (82.67%), Postives = 131/150 (87.33%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
             +P Y  FFGVMG T+AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLI   +     +  S   LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALIL+TK
Sbjct:    5 DQPSYVAFFGVMGATAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIGSSISKDYTLYKSFLDLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILTTK 154

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Nematostella
Match: EDO28376 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6M9])

HSP 1 Score: 88.1965 bits (217), Expect = 1.242e-22
Identity = 45/46 (97.83%), Postives = 46/46 (100.00%), Query Frame = 2

Query:  392 IGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            IGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALIL+TK
Sbjct:    6 IGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILTTK 51

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Nematostella
Match: EDO46167 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQU4])

HSP 1 Score: 48.1358 bits (113), Expect = 9.222e-7
Identity = 44/158 (27.85%), Postives = 85/158 (53.80%), Query Frame = 2

Query:   95 TPF-FGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQK-----LDSSLKMEN-------SLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +P+ +  +G+  A+    +GAA+G   +G  I    V  P +  K+++ ++    +AIYG++++++++       L++  K  N         K  GAG++VG   LA G  +G+VG       AQ   LFV ++++ IF   +GL+G+I+A+I ++ 
Sbjct:   49 SPYMWACLGIAIAIALSVVGAAWGILLTGASICGGGVKAPRIKAKNLVSIIFCEAVAIYGIIMSIVLSNSVTVSPLEAFEKPGNLMQLYTAGYKIFGAGMTVGFCNLACGICVGLVGSGAALADAQNGALFVKILIVEIFGSAIGLFGVIIAIIQASD 206

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Medaka
Match: ATP6V0C (V-type proton ATPase 16 kDa proteolipid subunit [Source:NCBI gene;Acc:101160850])

HSP 1 Score: 202.216 bits (513), Expect = 3.920e-65
Identity = 125/149 (83.89%), Postives = 135/149 (90.60%), Query Frame = 2

Query:   83 EPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
             P Y+PFF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +  ++ +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    5 SPEYSPFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNVAENISLFKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 153

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Medaka
Match: ATP6V0C (V-type proton ATPase 16 kDa proteolipid subunit [Source:NCBI gene;Acc:101159507])

HSP 1 Score: 201.83 bits (512), Expect = 5.314e-65
Identity = 125/150 (83.33%), Postives = 134/150 (89.33%), Query Frame = 2

Query:   80 SEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
              P Y+PFF VMG ++AMVF ALGAAYGTAKSGTGIA+M+VMRPELIMKSIIPVVMAGIIAIYGLVVAVLIA  +   + +  S  +LGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    5 ESPEYSPFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNISERVSLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 154

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Medaka
Match: atp6v0b (ATPase H+ transporting V0 subunit b [Source:NCBI gene;Acc:101162246])

HSP 1 Score: 55.4546 bits (132), Expect = 9.932e-9
Identity = 48/156 (30.77%), Postives = 86/156 (55.13%), Query Frame = 2

Query:   95 TPF-FGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLI---AQKLDSSL-------KMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +PF +  +G+  A+    +GAA+G   +G+ I    V  P +  K+++ ++    +AIYG+++A++I   A++   +          +      GAGL+VG S L  G  +GIVG       AQ P LFV ++++ IF   +GL+G+IVA++ ++K
Sbjct:   51 SPFMWANLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAERFSGTTPETIGARNYQAGYSMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSK 206

[Close]

Query:   95 TPF-FGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLI---AQKLDSSL-------KMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            +PF +  +G+  A+    +GAA+G   +G+ I    V  P +  K+++ ++    +AIYG+++A++I   A++   +          +      GAGL+VG S L  G  +GIVG       AQ P LFV ++++ IF   +GL+G+IVA++ ++K
Sbjct:   51 SPFMWANLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAERFSGTTPETIGARNYQAGYSMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSK 206

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Planmine SMEST
Match: SMESG000068628.1 (SMESG000068628.1)

HSP 1 Score: 252.292 bits (643), Expect = 7.159e-85
Identity = 151/151 (100.00%), Postives = 151/151 (100.00%), Query Frame = 2

Query:   77 MSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYXXXXXXXXXXXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 529
            MSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct:    1 MSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 151

[Close]

BLAST of V-type proton ATPase proteolipid subunit vs. Planmine SMEST
Match: SMESG000042238.1 (SMESG000042238.1)

HSP 1 Score: 50.0618 bits (118), Expect = 3.947e-7
Identity = 39/135 (28.89%), Postives = 68/135 (50.37%), Query Frame = 2

Query:  146 LGAAYGTAKSGTGIASMAVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAQKL---DSSLKMENSLKYXXXXXXXXX--------XXXXXXXXIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALI 517
            LGAA G   +G+ I    V  P +  K+++ ++    +AIYG+++A++I+Q +   D S+   N LK   A              S L  G  +G+VG       +    LFV ++++ IF   +GL+G+IV ++
Sbjct:   64 LGAALGIYTTGSSILGAGVKTPRIRTKNLVSIIFCEAVAIYGIIMAIVISQNIASFDRSIASFNVLKANYAAAFRMFGAGLTVGLSNLVCGICVGVVGSGAALADSANASLFVKILIVEIFGSAIGLFGVIVGIL 198

The following BLAST results are available for this feature:

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Human
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Celegans
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Fly
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Zebrafish
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Xenopus
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Mouse
BLAST of V-type proton ATPase proteolipid subunit vs. UniProt/SwissProt
BLAST of V-type proton ATPase proteolipid subunit vs. TrEMBL
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Cavefish
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Sea Lamprey
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Yeast
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Nematostella
BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Medaka
BLAST of V-type proton ATPase proteolipid subunit vs. Planmine SMEST

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ATP6V0C	8.170e-63	83.33	ATPase H+ transporting V0 subunit c [Source:HGNC S...	[more]
ATP6V0C	3.862e-42	86.61	ATPase H+ transporting V0 subunit c [Source:HGNC S...	[more]
ATP6V0C	3.862e-42	86.61	ATPase H+ transporting V0 subunit c [Source:HGNC S...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vha-3	6.418e-53	69.80	V-type proton ATPase 16 kDa proteolipid subunit 2/...	[more]
vha-3	6.418e-53	69.80	V-type proton ATPase 16 kDa proteolipid subunit 2/...	[more]
vha-2	6.418e-53	69.80	V-type proton ATPase 16 kDa proteolipid subunit 2 ...	[more]
vha-1	9.971e-48	65.58	V-type proton ATPase 16 kDa proteolipid subunit 1 ...	[more]
vha-1	9.971e-48	65.58	V-type proton ATPase 16 kDa proteolipid subunit 1 ...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Vha16-1	6.228e-61	80.26	gene:FBgn0262736 transcript:FBtr0086153	[more]
Vha16-1	6.228e-61	80.26	gene:FBgn0262736 transcript:FBtr0086152	[more]
Vha16-1	6.228e-61	80.26	gene:FBgn0262736 transcript:FBtr0086151	[more]
Vha16-1	6.228e-61	80.26	gene:FBgn0262736 transcript:FBtr0086150	[more]
Vha16-3	1.947e-60	78.67	gene:FBgn0028667 transcript:FBtr0076090	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
atp6v0ca	9.520e-66	82.35	ATPase H+ transporting V0 subunit ca [Source:ZFIN;...	[more]
atp6v0ca	9.520e-66	82.35	ATPase H+ transporting V0 subunit ca [Source:ZFIN;...	[more]
atp6v0cb	3.997e-65	83.89	ATPase H+ transporting V0 subunit cb [Source:ZFIN;...	[more]
atp6v0b	4.360e-8	30.13	ATPase H+ transporting V0 subunit b [Source:ZFIN;A...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
atp6v0c	1.191e-65	86.00	ATPase, H+ transporting, lysosomal 16kDa, V0 subun...	[more]
atp6v0c	9.703e-65	85.33	ATPase, H+ transporting, lysosomal 16kDa, V0 subun...	[more]
atp6v0b	2.118e-8	31.88	ATPase, H+ transporting, lysosomal 21kDa, V0 subun...	[more]
atp6v0b	2.553e-7	32.09	ATPase, H+ transporting, lysosomal 21kDa, V0 subun...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Atp6v0c	1.473e-64	84.00	ATPase, H+ transporting, lysosomal V0 subunit C [S...	[more]
Atp6v0c	1.473e-64	84.00	ATPase, H+ transporting, lysosomal V0 subunit C [S...	[more]
Atp6v0c	8.025e-61	83.45	ATPase, H+ transporting, lysosomal V0 subunit C [S...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P63081\|VATL_RAT	1.030e-63	84.00	V-type proton ATPase 16 kDa proteolipid subunit OS...	[more]
sp\|P63082\|VATL_MOUSE	1.030e-63	84.00	V-type proton ATPase 16 kDa proteolipid subunit OS...	[more]
sp\|O18882\|VATL_SHEEP	1.113e-62	83.33	V-type proton ATPase 16 kDa proteolipid subunit OS...	[more]
sp\|P23956\|VATL_BOVIN	2.541e-62	81.94	V-type proton ATPase 16 kDa proteolipid subunit OS...	[more]
sp\|Q03105\|VATL_TORMA	3.445e-62	84.46	V-type proton ATPase 16 kDa proteolipid subunit OS...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267DLB5	1.831e-65	80.79	V-type proton ATPase proteolipid subunit OS=Macros...	[more]
A0A448WK92	4.343e-65	88.59	V-type proton ATPase proteolipid subunit OS=Protop...	[more]
A0A3B3XBH1	1.071e-63	83.44	V-type proton ATPase proteolipid subunit OS=Poecil...	[more]
A0A3B3UP06	1.071e-63	83.44	V-type proton ATPase proteolipid subunit OS=Poecil...	[more]
A0A1A7WUY8	1.619e-63	83.55	V-type proton ATPase proteolipid subunit (Fragment...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
atp6v0cb	2.006e-66	84.00	V-type proton ATPase 16 kDa proteolipid subunit-li...	[more]
atp6v0ca	3.616e-65	81.70	V-type proton ATPase 16 kDa proteolipid subunit [S...	[more]
atp6v0b	3.425e-8	30.77	ATPase H+ transporting V0 subunit b [Source:NCBI g...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
atp6v0ca	2.644e-58	87.97	ATPase H+ transporting V0 subunit ca [Source:ZFIN;...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
VMA3	6.289e-53	67.95	Proteolipid subunit c of the V0 domain of vacuolar...	[more]
VMA11	3.804e-47	62.00	Vacuolar ATPase V0 domain subunit c'; involved in ...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO45670	3.223e-63	82.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28376	1.242e-22	97.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46167	9.222e-7	27.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ATP6V0C	3.920e-65	83.89	V-type proton ATPase 16 kDa proteolipid subunit [S...	[more]
ATP6V0C	5.314e-65	83.33	V-type proton ATPase 16 kDa proteolipid subunit [S...	[more]
atp6v0b	9.932e-9	30.77	ATPase H+ transporting V0 subunit b [Source:NCBI g...	[more]
atp6v0b	9.932e-9	30.77	ATPase H+ transporting V0 subunit b [Source:NCBI g...	[more]

BLAST of V-type proton ATPase proteolipid subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000068628.1	7.159e-85	100.00	SMESG000068628.1	[more]
SMESG000042238.1	3.947e-7	28.89	SMESG000042238.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016201 ID=SMED30016201|Name=V-type proton ATPase proteolipid subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=917bp
AAATAAATATACCTTGTTTTAATTATTTAAATAATTACGTTTTTGGAAGT
AATAATTCATTTTAATAATATTGCAAATGTCAGAACCTATTTATACTCCT
TTCTTTGGTGTCATGGGGGTAACCTCGGCTATGGTATTTTGCGCCCTAGG
TGCCGCTTATGGAACTGCTAAGTCAGGAACTGGAATTGCATCTATGGCCG
TGATGAGACCAGAATTAATCATGAAGTCCATTATTCCAGTTGTTATGGCG
GGTATTATAGCTATTTATGGACTAGTTGTTGCTGTTCTTATTGCGCAAAA
ATTGGACTCCAGTCTTAAAATGGAAAATTCTCTGAAATATCTTGGAGCCG
GATTAAGTGTTGGTCTCAGTGGTTTGGCAGCTGGCTTTGCAATCGGTATA
GTTGGTGATGCAGGTGTTCGAGGTACTGCACAACAACCTCGTCTATTCGT
CGGAATGATTCTTATTCTAATTTTTGCTGAAGTCCTTGGATTATATGGCT
TAATTGTTGCTTTAATATTGTCCACAAAGTAAATGCAAACAACTGAAATG
TGATTAACTTAAGCATAATTCGTTAAAAGTATCGCCATTATTTGTAAAAT
GTTAGAATATATTTTGACAATTTTATGTAATTTGTTATACGTATTTGCAA
TATCTTAGTTCTGTCAAATAATTTGATGTTTGTTAATATTGACCTCGCTG
ATGTTGATTATGGTAGTTAGTGGACTGTTATTAAAGCAATGTATTTATTT
ATATTGTAATTGGATTAATTATAAAATTGACAAGAAATTATTTTTTAATG
CATGGTTTCTCAGTGATAGTTTTTAGGAAATAGGTTATTTTTTCTGAAAT
CTATAAGTCCATTAATAATTTATTTGTAATATTTAATTTAAATAGATGAA
TTTATGACTTAAACAAA

protein sequence of SMED30016201-orf-1

>SMED30016201-orf-1 ID=SMED30016201-orf-1|Name=SMED30016201-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=152bp
MSEPIYTPFFGVMGVTSAMVFCALGAAYGTAKSGTGIASMAVMRPELIMK
SIIPVVMAGIIAIYGLVVAVLIAQKLDSSLKMENSLKYLGAGLSVGLSGL
AAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILST
K*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:1902600	hydrogen ion transmembrane transport
GO:0015991	ATP hydrolysis coupled proton transport
GO:0006810	transport
GO:0006811	ion transport
GO:0015992	proton transport

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR011555	ATPase_proteolipid_su_C_euk
IPR035921	F/V-ATP_Csub_sf
IPR000245	ATPase_proteolipid_csu
IPR002379	ATPase_proteolipid_c-like_dom

Vocabulary: **cellular component**
Term	Definition
GO:0033179	proton-transporting V-type ATPase, V0 domain
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0005773	vacuole
GO:0005774	vacuolar membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **molecular function**
Term	Definition
GO:0015078	hydrogen ion transmembrane transporter activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000245	V-ATPase proteolipid subunit	PRINTS	PR00122	VACATPASE	coord: 100..126 score: 86.45 coord: 26..50 score: 80.32 coord: 52..76 score: 68.11 coord: 127..150 score: 82.02
IPR011555	V-ATPase proteolipid subunit C, eukaryotic	TIGRFAM	TIGR01100	TIGR01100	coord: 9..114 e-value: 4.3E-48 score: 160.0
IPR002379	V-ATPase proteolipid subunit C-like domain	PFAM	PF00137	ATP-synt_C	coord: 14..72 e-value: 6.4E-14 score: 52.0 coord: 89..148 e-value: 1.7E-22 score: 79.5
None	No IPR available	GENE3D	G3DSA:1.20.120.610		coord: 7..151 e-value: 5.9E-59 score: 199.9
None	No IPR available	PANTHER	PTHR10263	V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT	coord: 3..151
None	No IPR available	PANTHER	PTHR10263:SF5	V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT	coord: 3..151
None	No IPR available	CDD	cd18175	ATP-synt_Vo_c_ATP6C_rpt1	coord: 9..76 e-value: 1.25336E-30 score: 103.384
None	No IPR available	CDD	cd18176	ATP-synt_Vo_c_ATP6C_rpt2	coord: 89..149 e-value: 8.61154E-29 score: 98.7317
None	No IPR available	TMHMM	TMhelix		coord: 10..31
None	No IPR available	TMHMM	TMhelix		coord: 88..110
None	No IPR available	TMHMM	TMhelix		coord: 123..145
None	No IPR available	TMHMM	TMhelix		coord: 51..73
IPR035921	F/V-ATP synthase subunit C superfamily	SUPERFAMILY	SSF81333	F1F0 ATP synthase subunit C	coord: 9..74
IPR035921	F/V-ATP synthase subunit C superfamily	SUPERFAMILY	SSF81333	F1F0 ATP synthase subunit C	coord: 83..150