Kynurenine 3-monooxygenase

Overview
NameKynurenine 3-monooxygenase
Smed IDSMED30016169
Length (bp)1514
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Kynurenine 3-monooxygenase (SMED30016169) t-SNE clustered cells

Violin plots show distribution of expression levels for Kynurenine 3-monooxygenase (SMED30016169) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016169

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30016169SMESG000055918.1 dd_Smed_v6_25479_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30016169SMESG000055918.1 Contig38359newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30016169SMESG000055918.1 Contig38359uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30016169SMESG000055918.1 Contig42156newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30016169SMESG000055918.1 Contig42156uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Human
Match: KMO (kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc:HGNC:6381])

HSP 1 Score: 310.842 bits (795), Expect = 6.150e-100
Identity = 158/396 (39.90%), Postives = 251/396 (63.38%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFL-SEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            + + I V E   D R    T GRSINL+LSHRG  ALK VGL+++I++  IPM ARM+H ++      PYG  +Q I ++ R+ +N+ LLT  E   N+++ FN +L+  +  + +   L S+K   ++  D ++G DGA+STVR  + K  R ++S++YIPHGY+EL  PP  +  + M+   LHIWPR+ FM+I LPN++ SF+  LFMPFE ++++ ++ ++  FF   FPDA  LIG+  L + FF      M++++C+ ++F   C+++GDAAHA+VPF+GQGMN+GFED ++F E++     DL      F++ R  D  A+ DL+ +NY E+R +V    F  +K ++  ++ + PS +IPLYTMV F+RI Y + ++    Q K++ +
Sbjct:   30 RNFQIDVYEAREDTRVATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPP-KNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINK 424
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Human
Match: KMO (kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc:HGNC:6381])

HSP 1 Score: 298.13 bits (762), Expect = 3.249e-95
Identity = 155/396 (39.14%), Postives = 245/396 (61.87%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFL-SEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            + + I V E   D R    T GRSINL+LSHRG  ALK VGL+++I++  IPM ARM+H ++      PYG  +Q I ++ R+ +N+ LLT  E   N+++ FN +L+  +  + +   L S+K   ++  D ++G DGA+STVR  + K  R ++S++YIPHGY+EL  PP  +  + M+   LHIWPR+ FM+I LPN++ SF+  LFMPFE ++++ ++ ++  FF   FPDA  LIG+  L + FF      M++++C+ ++F   C+++GDAAHA+VPF+GQGMN+GFED ++F E++     DL      F++ R  D  A+ DL+ +NY E             K ++  ++ + PS +IPLYTMV F+RI Y + ++    Q K++ +
Sbjct:   30 RNFQIDVYEAREDTRVATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPP-KNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIE-------------KNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINK 411
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Human
Match: KMO (kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc:HGNC:6381])

HSP 1 Score: 274.248 bits (700), Expect = 3.409e-86
Identity = 139/339 (41.00%), Postives = 217/339 (64.01%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFL-SEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDEL 1175
            + + I V E   D R    T GRSINL+LSHRG  ALK VGL+++I++  IPM ARM+H ++      PYG  +Q I ++ R+ +N+ LLT  E   N+++ FN +L+  +  + +   L S+K   ++  D ++G DGA+STVR  + K  R ++S++YIPHGY+EL  PP  +  + M+   LHIWPR+ FM+I LPN++ SF+  LFMPFE ++++ ++ ++  FF   FPDA  LIG+  L + FF      M++++C+ ++F   C+++GDAAHA+VPF+GQGMN+GFED ++F E++     DL      F++ R  D  A+ DL+ +NY E+
Sbjct:   30 RNFQIDVYEAREDTRVATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPP-KNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEV 367
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Human
Match: KMO (kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc:HGNC:6381])

HSP 1 Score: 77.7962 bits (190), Expect = 5.299e-16
Identity = 39/109 (35.78%), Postives = 65/109 (59.63%), Query Frame = 3 
Query: 1020 GMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            GMN+GFED ++F E++     DL      F++ R  D  A+ DL+ +NY E+R +V    F  +K ++  ++ + PS +IPLYTMV F+RI Y + ++    Q K++ +
Sbjct:    2 GMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINK 110
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Celegans
Match: kmo-1 (Kynurenine 3-monooxygenase [Source:UniProtKB/Swiss-Prot;Acc:Q21795])

HSP 1 Score: 322.398 bits (825), Expect = 2.939e-105
Identity = 174/423 (41.13%), Postives = 266/423 (62.88%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLK---RFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKK--IAKFLSE----------------KEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPF-EYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITV 1370
            +D+ V E   DIR      GRSINL+LS RG +AL+ VGL E I+   +P+YAR++H  N+D K   R PYG   + I +I+R+ +NE+++T+ E + N++ FF  K+ +VD+ KK  + +  S+                 E+H +  D ++  DGA+S VR+ +    R +FS+EYI HGY+EL+     +N+   ++   H+WPR  F LI L N D +F+  +F PF E+   + ++E++  FF  NFPDAF L+GK ++A  F   KP  +V+I+C+P++F    ++MGDAAHAMVPFYGQGMN GFED ++F E L+ +  D+ K    ++  R  DA ++ DLA +NY+EL+  V   S++LRK  D +MN +FP  WIPLY+MV F+RIPY++ +E +++QDKIL+R+     T+
Sbjct:   25 WDVSVYEFRKDIRTMKHVQGRSINLALSQRGKSALEAVGLKEYIVNQGVPLYARLIH--NKDGKTYSRQPYGKPGEHIVSINRRHLNEVMITQAEKSPNVKFFFEHKVKNVDYDKKQLVVQCTSQPSKIPTFGNKSPPQEHAEFH-VEADLILACDGAYSAVRRSLMTIPRFDFSQEYIEHGYVELNIMAN-NNEFAFEENVFHLWPRGHFTLIALANRDKTFTVTIFAPFSEFEKHMSTSEDVLSFFEENFPDAFLLLGKEHIADTFNRVKPQPLVSIKCSPHSFFDNLVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEYGNDIAKAVKVYSDGRVNDAHSINDLAMYNYEELKDLVNKSSYKLRKKFDTIMNSIFPKSWIPLYSMVTFSRIPYSEVIERRKRQDKILSRIMTTTSTL 443
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Celegans
Match: kmo-2 (Kynurenine 3-MonoOxygenase [Source:UniProtKB/TrEMBL;Acc:Q21794])

HSP 1 Score: 162.925 bits (411), Expect = 1.682e-44
Identity = 115/417 (27.58%), Postives = 205/417 (49.16%), Query Frame = 3 
Query:  180 VCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVH--GVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKK--CLHIWPRSEFMLIGLPNLDGSFSGILFMPF-EYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYD-LDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSF---------RLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSI 1385
            V E   D RG +   G+SINL+L  R ++ +K +GL E+++   +P+  ++ H       LKR P    +  I  I+R+ +++IL+ + E   N++  FN K    D + +     +      +  D  +  DGAHS++R+ + K    NFS++Y   GYI+L      ++    D K    + W R   +L+ + N D S +  +F  F E+   +        FF  NF + F+++G+ ++       KP  +++++C+ + F    ++MGDAAHAMVPF GQG+N GFED ++  EI+  ++ D L+    E++K R  +   +      N  E  +N+TL S           +R  I  L+ ++FPS     +T+  F+R  Y++   + +  +K  +    + I  +   I
Sbjct:   29 VYESRFDPRGNHMENGKSINLALGVRAMSTMKRIGLKEKVIHIGVPIRDQIAHFGDTKGKLKRLPVLNDDDFILTINRQELSQILINEAEKYNNVKFHFNCKATKFDLKSESLIVQNSDNLSTVDGDLFLACDGAHSSIRRSLLKAPGFNFSQKYSEFGYIDL----SVNSTQQCDLKLGTHYSWRRRGIILVAIVNKDQSLTVSMFATFSEFESNLVGPVESVLFFKNNFYEIFKILGEDHIRNTIARNKPQAIISVQCSQHVFFDKLVLMGDAAHAMVPFNGQGVNCGFEDCLVLQEIMDQYEEDELEDVIKEYSKVRTNETNII------NQMEWDVNLTLTSSVHGSLGWIREIRAHIKLLLCFIFPS----SFTLAAFSREKYSEIARKAQIVEKCTSLFTNVFIVFIISVI 431
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Celegans
Match: kmo-2 (Kynurenine 3-MonoOxygenase [Source:UniProtKB/TrEMBL;Acc:Q21794])

HSP 1 Score: 158.688 bits (400), Expect = 2.188e-43
Identity = 110/402 (27.36%), Postives = 199/402 (49.50%), Query Frame = 3 
Query:  225 GRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVH--GVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKK--CLHIWPRSEFMLIGLPNLDGSFSGILFMPF-EYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYD-LDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSF---------RLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSI 1385
            G+SINL+L  R ++ +K +GL E+++   +P+  ++ H       LKR P    +  I  I+R+ +++IL+ + E   N++  FN K    D + +     +      +  D  +  DGAHS++R+ + K    NFS++Y   GYI+L      ++    D K    + W R   +L+ + N D S +  +F  F E+   +        FF  NF + F+++G+ ++       KP  +++++C+ + F    ++MGDAAHAMVPF GQG+N GFED ++  EI+  ++ D L+    E++K R  +   +      N  E  +N+TL S           +R  I  L+ ++FPS     +T+  F+R  Y++   + +  +K  +    + I  +   I
Sbjct:    4 GKSINLALGVRAMSTMKRIGLKEKVIHIGVPIRDQIAHFGDTKGKLKRLPVLNDDDFILTINRQELSQILINEAEKYNNVKFHFNCKATKFDLKSESLIVQNSDNLSTVDGDLFLACDGAHSSIRRSLLKAPGFNFSQKYSEFGYIDL----SVNSTQQCDLKLGTHYSWRRRGIILVAIVNKDQSLTVSMFATFSEFESNLVGPVESVLFFKNNFYEIFKILGEDHIRNTIARNKPQAIISVQCSQHVFFDKLVLMGDAAHAMVPFNGQGVNCGFEDCLVLQEIMDQYEEDELEDVIKEYSKVRTNETNII------NQMEWDVNLTLTSSVHGSLGWIREIRAHIKLLLCFIFPS----SFTLAAFSREKYSEIARKAQIVEKCTSLFTNVFIVFIISVI 391
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Celegans
Match: kmo-2 (Kynurenine 3-MonoOxygenase [Source:UniProtKB/TrEMBL;Acc:Q21794])

HSP 1 Score: 158.688 bits (400), Expect = 2.188e-43
Identity = 110/402 (27.36%), Postives = 199/402 (49.50%), Query Frame = 3 
Query:  225 GRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVH--GVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKK--CLHIWPRSEFMLIGLPNLDGSFSGILFMPF-EYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYD-LDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSF---------RLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSI 1385
            G+SINL+L  R ++ +K +GL E+++   +P+  ++ H       LKR P    +  I  I+R+ +++IL+ + E   N++  FN K    D + +     +      +  D  +  DGAHS++R+ + K    NFS++Y   GYI+L      ++    D K    + W R   +L+ + N D S +  +F  F E+   +        FF  NF + F+++G+ ++       KP  +++++C+ + F    ++MGDAAHAMVPF GQG+N GFED ++  EI+  ++ D L+    E++K R  +   +      N  E  +N+TL S           +R  I  L+ ++FPS     +T+  F+R  Y++   + +  +K  +    + I  +   I
Sbjct:    4 GKSINLALGVRAMSTMKRIGLKEKVIHIGVPIRDQIAHFGDTKGKLKRLPVLNDDDFILTINRQELSQILINEAEKYNNVKFHFNCKATKFDLKSESLIVQNSDNLSTVDGDLFLACDGAHSSIRRSLLKAPGFNFSQKYSEFGYIDL----SVNSTQQCDLKLGTHYSWRRRGIILVAIVNKDQSLTVSMFATFSEFESNLVGPVESVLFFKNNFYEIFKILGEDHIRNTIARNKPQAIISVQCSQHVFFDKLVLMGDAAHAMVPFNGQGVNCGFEDCLVLQEIMDQYEEDELEDVIKEYSKVRTNETNII------NQMEWDVNLTLTSSVHGSLGWIREIRAHIKLLLCFIFPS----SFTLAAFSREKYSEIARKAQIVEKCTSLFTNVFIVFIISVI 391
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Fly
Match: cn (gene:FBgn0000337 transcript:FBtr0344723)

HSP 1 Score: 306.605 bits (784), Expect = 7.782e-99
Identity = 171/390 (43.85%), Postives = 241/390 (61.79%), Query Frame = 3 
Query:  186 EKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYG-LSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS-EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRL 1349
            E   DIR      GRSINL+LS RG  AL  VGL++E+LA +IPM  RM+H V  +     Y  ++NQC+ ++ R+ +NE+LL   +   NI+  F  KL   + R+   +F +  KE      D ++G DGA S+VRQ   +    N+S+EYI  GY+EL  P  + +   M    LHIWPR+ FM+I LPN D SF+  L MPFE +  I++  +L +FF  NF DA  LIG+  L + FF T+P  +V+I+C PY++    +I+GDAAHAMVP+YGQGMN+G EDV +  +IL      LD+T   FT++R  DA A+CDLA +NY E+R      +FRLRK +D L+  LFP  WIPLY  V F+ +PY +C+  ++ QD++L R+
Sbjct:   58 EYREDIRQALVVQGRSINLALSQRGRKALAAVGLEQEVLATAIPMRGRMLHDVRGNSSVVLYDPINNQCLYSVGRRQLNEVLLNACDKLPNIRCHFEHKLTSANLREGSMEFRNPAKEAVAAHADLIVGCDGAFSSVRQNNVRLPGFNYSQEYIETGYLELCIPSKSGDFQ-MPANYLHIWPRNTFMMIALPNQDKSFTVTLSMPFEIFAGIQNQNDLLEFFKLNFRDALPLIGEQQLIKDFFKTRPQFLVSIKCRPYHYADKALILGDAAHAMVPYYGQGMNAGMEDVTLLTDILAKQ-LPLDETLALFTESRWQDAFAICDLAMYNYVEMRDLTKRWTFRLRKWLDTLLFRLFPG-WIPLYNSVSFSSMPYRQCIANRKWQDQLLKRI 444
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Zebrafish
Match: kmo (kynurenine 3-monooxygenase [Source:NCBI gene;Acc:368242])

HSP 1 Score: 330.872 bits (847), Expect = 3.845e-108
Identity = 175/394 (44.42%), Postives = 244/394 (61.93%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFL-SEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            +D+ V E   DIR      GRSINL+LSHRG  ALK VG++++I++  IPM+ARM+H VN      PYG   Q I ++DR  +N+ LLT  E   N +L FN KL D   +     F+ S+ +  E   D ++G DGA S VR+   +  R N+S+ YIPHGY+EL  PP  D    M+   LHIWPR+ FM+I LPNLD +F+  LFMPFE +++I + + L +FF+  FPD+  LIG   L + FF      MV+++C PY+    C++MGDAAHA+VPFYGQGMN+GFED ++F EI+   + +L     E+T+ R  D  A+ DLA +NY E+R +V    F  RK +DNL+++  P   +PLYTMV FTR  Y   +     Q+K++TR
Sbjct:   40 FDVEVYESREDIRQAKVVKGRSINLALSHRGRQALKHVGMEDKIVSKGIPMHARMIHNVNGKRSPIPYGKKGQYILSVDRANLNKELLTAAEAYPNTRLNFNHKLHDWSPKTGTMTFIGSDGQKTETQADLIVGCDGAFSAVRKQFLRQSRFNYSQTYIPHGYMELTMPP-KDGDFAMEPNYLHIWPRNTFMMIALPNLDRTFTCTLFMPFEDFEKIRTGDELLRFFHKYFPDSVPLIGVEALKQDFFRLPAQAMVSVKCCPYHLFEKCVLMGDAAHAVVPFYGQGMNAGFEDCLVFDEIMDQFNENLAAVLQEYTRVRVPDDHAIADLAMYNYIEMRAHVNSKYFIFRKYLDNLLHFFMPQTIVPLYTMVTFTRTRYNDAVNRWHWQNKVITR 432
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Xenopus
Match: bend3 (BEN domain containing 3 [Source:Xenbase;Acc:XB-GENE-6051071])

HSP 1 Score: 324.709 bits (831), Expect = 1.367e-105
Identity = 176/393 (44.78%), Postives = 243/393 (61.83%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKE-YHEIAFDFLIGNDGAHSTVR-QFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKIL 1340
            + + + E   DIR      GRSINL+LSHRGL ALK VGLDE+I A  IPM ARM+H V       PYG  +Q I ++DR  +N+ LL+  E   N+ + F  KL D +       FL+  E   E   D ++G DGA S VR QFM K+ R N+S  YIPHGY EL  PP    +  M+   LHIWPR+ FM+I LPNLD SF+  LFMPFE ++++ + + +  FF   FPD+  LIG+  L   FF   P  M++++C+ +     C+IMGDAAHA+VPFYGQGMN+GFED ++F E+++ +  +L     EF++ R  DA A+ DLA +NY E+R +V    F  RK +DN++N + P+ +IPLYTMV F+RI Y + +   + Q KI+
Sbjct:   32 FQVELYEAREDIRYARMVSGRSINLALSHRGLQALKAVGLDEKIAAMGIPMRARMIHSVKGRKSSIPYGKQHQYILSVDRANLNKELLSAAEKYSNVTMHFEHKLRDCNVDSGTMTFLNNMENIIEKKADLIVGCDGAFSVVRKQFMRKS-RFNYSHVYIPHGYKELTIPP-RKGEFAMEPNYLHIWPRNTFMMIALPNLDKSFTCTLFMPFEDFEKLTTGDQVLDFFKTYFPDSIELIGEKKLTEDFFLLPPQAMISVKCSSFCIDHKCVIMGDAAHAVVPFYGQGMNAGFEDCLVFSELMEQYQNNLRICLHEFSRLRVPDAHAISDLAMYNYKEMRAHVNSKWFIFRKQVDNILNAIMPTTFIPLYTMVTFSRIRYHEVILRWKWQKKII 422
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Xenopus
Match: bend3 (BEN domain containing 3 [Source:Xenbase;Acc:XB-GENE-6051071])

HSP 1 Score: 322.398 bits (825), Expect = 3.852e-105
Identity = 175/391 (44.76%), Postives = 241/391 (61.64%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKE-YHEIAFDFLIGNDGAHSTVR-QFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDK 1334
            + + + E   DIR      GRSINL+LSHRGL ALK VGLDE+I A  IPM ARM+H V       PYG  +Q I ++DR  +N+ LL+  E   N+ + F  KL D +       FL+  E   E   D ++G DGA S VR QFM K+ R N+S  YIPHGY EL  PP    +  M+   LHIWPR+ FM+I LPNLD SF+  LFMPFE ++++ + + +  FF   FPD+  LIG+  L   FF   P  M++++C+ +     C+IMGDAAHA+VPFYGQGMN+GFED ++F E+++ +  +L     EF++ R  DA A+ DLA +NY E+R +V    F  RK +DN++N + P+ +IPLYTMV F+RI Y + +   + Q K
Sbjct:   32 FQVELYEAREDIRYARMVSGRSINLALSHRGLQALKAVGLDEKIAAMGIPMRARMIHSVKGRKSSIPYGKQHQYILSVDRANLNKELLSAAEKYSNVTMHFEHKLRDCNVDSGTMTFLNNMENIIEKKADLIVGCDGAFSVVRKQFMRKS-RFNYSHVYIPHGYKELTIPP-RKGEFAMEPNYLHIWPRNTFMMIALPNLDKSFTCTLFMPFEDFEKLTTGDQVLDFFKTYFPDSIELIGEKKLTEDFFLLPPQAMISVKCSSFCIDHKCVIMGDAAHAVVPFYGQGMNAGFEDCLVFSELMEQYQNNLRICLHEFSRLRVPDAHAISDLAMYNYKEMRAHVNSKWFIFRKQVDNILNAIMPTTFIPLYTMVTFSRIRYHEVILRWKWQKK 420
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Xenopus
Match: bend3 (BEN domain containing 3 [Source:Xenbase;Acc:XB-GENE-6051071])

HSP 1 Score: 289.656 bits (740), Expect = 7.023e-92
Identity = 166/399 (41.60%), Postives = 233/399 (58.40%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKE-YHEIAFDFLIGNDGAHSTVR-QFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHV------MDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKIL 1340
            + + + E   DIR      GRSINL+LSHRGL ALK VGLDE+I A  IPM ARM+H V       PYG  +Q I ++DR  +N+ LL+  E   N+ + F  KL D +       FL+  E   E   D ++G DGA S VR QFM K+ R N+S  YIPHGY EL  PP             +D K         F+++ L   D SF+  LFMPFE ++++ + + +  FF   FPD+  LIG+  L   FF   P  M++++C+ +     C+IMGDAAHA+VPFYGQGMN+GFED ++F E+++ +  +L     EF++ R  DA A+ DLA +NY E+R +V    F  RK +DN++N + P+ +IPLYTMV F+RI Y + +   + Q KI+
Sbjct:   32 FQVELYEAREDIRYARMVSGRSINLALSHRGLQALKAVGLDEKIAAMGIPMRARMIHSVKGRKSSIPYGKQHQYILSVDRANLNKELLSAAEKYSNVTMHFEHKLRDCNVDSGTMTFLNNMENIIEKKADLIVGCDGAFSVVRKQFMRKS-RFNYSHVYIPHGYKELTIPPRKGEVRFSVVFLFLDAKMCK--KNKTFLMVCLFQQDKSFTCTLFMPFEDFEKLTTGDQVLDFFKTYFPDSIELIGEKKLTEDFFLLPPQAMISVKCSSFCIDHKCVIMGDAAHAVVPFYGQGMNAGFEDCLVFSELMEQYQNNLRICLHEFSRLRVPDAHAISDLAMYNYKEMRAHVNSKWFIFRKQVDNILNAIMPTTFIPLYTMVTFSRIRYHEVILRWKWQKKII 427
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Xenopus
Match: bend3 (BEN domain containing 3 [Source:Xenbase;Acc:XB-GENE-6051071])

HSP 1 Score: 271.166 bits (692), Expect = 7.486e-86
Identity = 155/372 (41.67%), Postives = 213/372 (57.26%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKE-YHEIAFDFLIGNDGAHSTVR-QFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMV 1277
            + + + E   DIR      GRSINL+LSHRGL ALK VGLDE+I A  IPM ARM+H V       PYG  +Q I ++DR  +N+ LL+  E   N+ + F  KL D +       FL+  E   E   D ++G DGA S VR QFM K+ R N+S  YIPHGY EL  PP                             D SF+  LFMPFE ++++ + + +  FF   FPD+  LIG+  L   FF   P  M++++C+ +     C+IMGDAAHA+VPFYGQGMN+GFED ++F E+++ +  +L     EF++ R  DA A+ DLA +NY E+R +V    F  RK +DN++N + P+ +IPLYTMV
Sbjct:   32 FQVELYEAREDIRYARMVSGRSINLALSHRGLQALKAVGLDEKIAAMGIPMRARMIHSVKGRKSSIPYGKQHQYILSVDRANLNKELLSAAEKYSNVTMHFEHKLRDCNVDSGTMTFLNNMENIIEKKADLIVGCDGAFSVVRKQFMRKS-RFNYSHVYIPHGYKELTIPPRKGE-------------------------DKSFTCTLFMPFEDFEKLTTGDQVLDFFKTYFPDSIELIGEKKLTEDFFLLPPQAMISVKCSSFCIDHKCVIMGDAAHAVVPFYGQGMNAGFEDCLVFSELMEQYQNNLRICLHEFSRLRVPDAHAISDLAMYNYKEMRAHVNSKWFIFRKQVDNILNAIMPTTFIPLYTMV 377
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Mouse
Match: Kmo (kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) [Source:MGI Symbol;Acc:MGI:2138151])

HSP 1 Score: 318.546 bits (815), Expect = 3.379e-103
Identity = 160/396 (40.40%), Postives = 251/396 (63.38%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS-EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            + + + V E   DIR      GRSINL+LS+RG  ALK +GL+++I++  +PM ARM+H ++      PYG  +Q I +I R+ +N+ LLT VE+  N ++ F  KL      + +   L  +K   ++  D ++G DGA+STVR  + K  R +++++YIPHGY+EL  PP  + ++ M+  CLHIWPR+ +M+I LPN+D SF+  LFMPFE ++ + +  ++  FF  NFPDA  L+G+  L R FF      M++++C+P++    C++MGDAAHA+VPF+GQGMN+GFED ++F E++   + +L     EF++ R  D  A+ DL+ +NY E+R +V    F  +K++D  ++ + PS +IPLYTMV FTRI Y + +     Q K++ R
Sbjct:   30 RNFQVDVYEAREDIRVAKSARGRSINLALSYRGRQALKAIGLEDQIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISRENLNKDLLTAVESYANAKVHFGHKLSKCIPEEGVLTVLGPDKVPRDVTCDLVVGCDGAYSTVRAHLMKKPRFDYTQQYIPHGYMELTIPP-KNGEYAMEPNCLHIWPRNAYMMIALPNMDKSFTCTLFMPFEEFERLPTRSDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKSHCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNNLSMCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQKLLDKFLHAIMPSTFIPLYTMVAFTRIRYHEAVLRWHWQKKVINR 424
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Mouse
Match: Kmo (kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) [Source:MGI Symbol;Acc:MGI:2138151])

HSP 1 Score: 276.559 bits (706), Expect = 2.093e-87
Identity = 142/361 (39.34%), Postives = 226/361 (62.60%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS-EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDE-----LRINVTLLSFRLRKIIDN 1226
            + + + V E   DIR      GRSINL+LS+RG  ALK +GL+++I++  +PM ARM+H ++      PYG  +Q I +I R+ +N+ LLT VE+  N ++ F  KL      + +   L  +K   ++  D ++G DGA+STVR  + K  R +++++YIPHGY+EL  PP  + ++ M+  CLHIWPR+ +M+I LPN+D SF+  LFMPFE ++ + +  ++  FF  NFPDA  L+G+  L R FF      M++++C+P++    C++MGDAAHA+VPF+GQGMN+GFED ++F E++   + +L     EF++ R  D  A+ DL+ +NY E     +R +  +L +  +K + N
Sbjct:   30 RNFQVDVYEAREDIRVAKSARGRSINLALSYRGRQALKAIGLEDQIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISRENLNKDLLTAVESYANAKVHFGHKLSKCIPEEGVLTVLGPDKVPRDVTCDLVVGCDGAYSTVRAHLMKKPRFDYTQQYIPHGYMELTIPP-KNGEYAMEPNCLHIWPRNAYMMIALPNMDKSFTCTLFMPFEEFERLPTRSDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKSHCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNNLSMCLPEFSRFRIPDDHAISDLSMYNYIEVAFTRIRYHEAVLRWHWQKKVIN 389
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Mouse
Match: Kmo (kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) [Source:MGI Symbol;Acc:MGI:2138151])

HSP 1 Score: 132.88 bits (333), Expect = 4.196e-35
Identity = 69/181 (38.12%), Postives = 108/181 (59.67%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS-EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKK 707
            + + V E   DIR      GRSINL+LS+RG  ALK +GL+++I++  +PM ARM+H ++      PYG  +Q I +I R+ +N+ LLT VE+  N ++ F  KL      + +   L  +K   ++  D ++G DGA+STVR  + K  R +++++YIPHGY+EL  PP    K + D +
Sbjct:   59 FQVDVYEAREDIRVAKSARGRSINLALSYRGRQALKAIGLEDQIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISRENLNKDLLTAVESYANAKVHFGHKLSKCIPEEGVLTVLGPDKVPRDVTCDLVVGCDGAYSTVRAHLMKKPRFDYTQQYIPHGYMELTIPPKNGEKCLYDDR 239
[Close]
BLAST of Kynurenine 3-monooxygenase vs. UniProt/SwissProt
Match: sp|Q86PM2|KMO_AEDAE (Kynurenine 3-monooxygenase OS=Aedes aegypti OX=7159 GN=kh PE=1 SV=2)

HSP 1 Score: 345.51 bits (885), Expect = 6.538e-113
Identity = 177/391 (45.27%), Postives = 244/391 (62.40%), Query Frame = 3 
Query:  186 EKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGL-SNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFL--SEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRL 1349
            E   DIR     IGRSINL+LS RG  AL  VGL++ +L   IPM  RM+H +  + K  PY   +NQCI ++ RK +NE+LL   E   NI L+FN KL   +  +    F+  + KE      D ++G DGA+S VR+ + K    ++S+ YI HGY+EL  PP  D    M    LHIWPR +FM+I LPN D +++  LFMPF  ++ I+ + +L KFF   FPDA  LIG+  L + FF T+P  +V I+C PYN GG  +I+GDAAHAMVPFYGQGMN+GFED  +  E+   H  D+D+   EF+  R  DA ++CDLA +NY E+R  VT  S+  RK +D L+ ++ P+ W+PLY  V F+ + Y+KC+  ++ QDKILTR+
Sbjct:   47 EYREDIRTAELVIGRSINLALSARGRKALAEVGLEDALLQHGIPMKGRMLHDLKGNRKIVPYDANTNQCIYSVGRKHLNEVLLDAAEKYPNIHLYFNKKLQSANLDEGEMSFIDPTTKESTHTKADLIVGCDGAYSAVRKEIVKRPGYDYSQTYIEHGYLELCIPPTKDGDFAMPHNYLHIWPRGKFMMIALPNQDRTWTVTLFMPFTNFNSIKCDGDLLKFFRTYFPDAIDLIGRERLVKDFFKTRPQSLVMIKCKPYNVGGKAVIIGDAAHAMVPFYGQGMNAGFEDCTVLTELFNQHGSDVDRILAEFSDTRWEDAHSICDLAMYNYVEMRDLVTKRSYLFRKKLDELLYWMLPNTWVPLYNSVSFSHMRYSKCIANRKWQDKILTRV 437
[Close]
BLAST of Kynurenine 3-monooxygenase vs. UniProt/SwissProt
Match: sp|Q7Q6A7|KMO_ANOGA (Kynurenine 3-monooxygenase OS=Anopheles gambiae OX=7165 GN=kh PE=3 SV=2)

HSP 1 Score: 339.732 bits (870), Expect = 1.737e-110
Identity = 181/410 (44.15%), Postives = 247/410 (60.24%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGL-SNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS--EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGS 1382
            + +++ + E   DIR     IGRSINL+LS RG  AL  VGL++ +L   IPM  RM+H VN   K  PY   +NQCI ++ RK +NE+LL   E   NI L FN KLV  +  +     +    K+      D ++G DGA+S VR+ + K  R +FS+ YI HGY+EL  PP A  +  M    LHIWPR +FM+I LPN D +++  LFMPF  +  I     L  FF  +FPDA  LIG+  L + FF TK   +V I+C PY+ G   +I+GDAAHAMVPFYGQGMN+GFED  +  E+   +  DL +   EF++ R  DA A+CDLA +NY E+R  VT  S+ LRK +D L+ ++ P+ W+PLY  V F+ + Y+KC+  +  QDKILTR       VL+G+
Sbjct:   43 KGHEVNLYEYREDIRTAELVIGRSINLALSARGRRALAEVGLEDALLNHGIPMSGRMLHDVNGKCKIVPYDANTNQCIYSVGRKHLNEVLLNAAEKYPNIHLHFNHKLVSANLDEGNLSMVDPVTKDVKSARADLIVGCDGAYSAVRKEIVKRPRYDFSQTYIEHGYLELCIPPTAGGEFAMPHNYLHIWPRGQFMMIALPNQDRTWTVTLFMPFTQFHSITDQGLLLDFFRQHFPDAIELIGRERLVKDFFKTKAQPLVMIKCRPYHIGAKALIIGDAAHAMVPFYGQGMNAGFEDCSVLTELFNQYGTDLARILPEFSEKRWEDAHAICDLAMYNYIEMRDLVTKRSYLLRKKLDELLFWMMPNTWVPLYNSVSFSHMRYSKCIANRAWQDKILTR-------VLYGA 445
[Close]
BLAST of Kynurenine 3-monooxygenase vs. UniProt/SwissProt
Match: sp|Q1RLY6|KMO_DANRE (Kynurenine 3-monooxygenase OS=Danio rerio OX=7955 GN=kmo PE=2 SV=1)

HSP 1 Score: 330.102 bits (845), Expect = 7.740e-107
Identity = 175/394 (44.42%), Postives = 244/394 (61.93%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFL-SEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            +D+ V E   DIR      GRSINL+LSHRG  ALK VG++++I++  IPM+ARM+H VN      PYG   Q I ++DR  +N+ LLT  E   N +L FN KL D   +     F+ S+ +  E   D ++G DGA S VR+   +  R N+S+ YIPHGY+EL  PP  D    M+   LHIWPR+ FM+I LPNLD +F+  LFMPFE +++I + + L +FF+  FPD+  LIG   L + FF      MV+++C PY+    C++MGDAAHA+VPFYGQGMN+GFED ++F EI+   + +L     E+T+ R  D  A+ DLA +NY E+R +V    F  RK +DNL+++  P   +PLYTMV FTR  Y   +     Q+K++TR
Sbjct:   40 FDVEVYESREDIRQAKVVKGRSINLALSHRGRQALKHVGMEDKIISKGIPMHARMIHNVNGKRSPIPYGKKGQYILSVDRANLNKELLTAAEAYPNTRLNFNHKLHDWSPKTGTMTFIGSDGQKTETQADLIVGCDGAFSAVRKQFLRQSRFNYSQTYIPHGYMELTMPP-KDGDFAMEPNYLHIWPRNTFMMIALPNLDRTFTCTLFMPFEDFEKIRTGDELLRFFHKYFPDSVPLIGVEALKQDFFRLPAQAMVSVKCCPYHLFEKCVLMGDAAHAVVPFYGQGMNAGFEDCLVFDEIMDQFNENLVAVLQEYTRVRVPDDHAIADLAMYNYIEMRAHVNSKYFIFRKYLDNLLHFFMPKTIVPLYTMVTFTRTRYNDAVNRWHWQNKVITR 432
[Close]
BLAST of Kynurenine 3-monooxygenase vs. UniProt/SwissProt
Match: sp|Q6DIZ8|KMO_XENTR (Kynurenine 3-monooxygenase OS=Xenopus tropicalis OX=8364 GN=kmo PE=2 SV=1)

HSP 1 Score: 324.709 bits (831), Expect = 7.240e-105
Identity = 176/393 (44.78%), Postives = 243/393 (61.83%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKE-YHEIAFDFLIGNDGAHSTVR-QFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKIL 1340
            + + + E   DIR      GRSINL+LSHRGL ALK VGLDE+I A  IPM ARM+H V       PYG  +Q I ++DR  +N+ LL+  E   N+ + F  KL D +       FL+  E   E   D ++G DGA S VR QFM K+ R N+S  YIPHGY EL  PP    +  M+   LHIWPR+ FM+I LPNLD SF+  LFMPFE ++++ + + +  FF   FPD+  LIG+  L   FF   P  M++++C+ +     C+IMGDAAHA+VPFYGQGMN+GFED ++F E+++ +  +L     EF++ R  DA A+ DLA +NY E+R +V    F  RK +DN++N + P+ +IPLYTMV F+RI Y + +   + Q KI+
Sbjct:   32 FQVELYEAREDIRYARMVSGRSINLALSHRGLQALKAVGLDEKIAAMGIPMRARMIHSVKGRKSSIPYGKQHQYILSVDRANLNKELLSAAEKYSNVTMHFEHKLRDCNVDSGTMTFLNNMENIIEKKADLIVGCDGAFSVVRKQFMRKS-RFNYSHVYIPHGYKELTIPP-RKGEFAMEPNYLHIWPRNTFMMIALPNLDKSFTCTLFMPFEDFEKLTTGDQVLDFFKTYFPDSIELIGEKKLTEDFFLLPPQAMISVKCSSFCIDHKCVIMGDAAHAVVPFYGQGMNAGFEDCLVFSELMEQYQNNLRICLHEFSRLRVPDAHAISDLAMYNYKEMRAHVNSKWFIFRKQVDNILNAIMPTTFIPLYTMVTFSRIRYHEVILRWKWQKKII 422
[Close]
BLAST of Kynurenine 3-monooxygenase vs. UniProt/SwissProt
Match: sp|A8Y432|KMO_CAEBR (Kynurenine 3-monooxygenase OS=Caenorhabditis briggsae OX=6238 GN=kmo-1 PE=3 SV=1)

HSP 1 Score: 324.324 bits (830), Expect = 8.095e-105
Identity = 179/434 (41.24%), Postives = 265/434 (61.06%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLK---RFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKK------------IAKF-----LSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPF-EYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITV-LFGSILILTNN 1403
            +D+ V E   DIR      GRSINL+LS RG +AL+ VGL E I+   +P+YAR+VH  N+D K   R PYG   + I +I+R+ +NE+++T+ E + N++ FF  K+  VD+ KK            I  F      +E E   +  D +I  DGA+S VR+ +    R +FS+EYI HGY+EL+     +N+   ++   H+WPR  F LI L N D +F+  +F PF E+   + + E +  FF  NFPDA+ L+GK ++A  F   KP  +V+I+C+P++F    ++MGDAAHAMVPFYGQGMN GFED ++F E L+  + D+      +++ R  DA  + DLA +NY+EL+  V   S++LRK  D  MN +FP  WIPLY+MV FTRIPY++ ++ + KQD+IL+ L K   T+ L G+ + + +N
Sbjct:   25 WDVSVYEFRKDIRTMKHVQGRSINLALSQRGKSALEAVGLKEYIVNQGVPLYARLVH--NKDGKTYSRQPYGKPGEHIVSINRRHLNEVMITQAEKSPNVKFFFEHKVKSVDYDKKQLVVQCTSQPSRIPTFGTKSPPAEHEEFHVEADLIIACDGAYSAVRRSLMTIPRFDFSQEYIEHGYVELNIMAN-NNEFAFEENVFHLWPRGHFTLIALANRDKTFTVTIFAPFTEFEKHMSTTEEVLSFFEENFPDAYLLLGKEHIADTFNRVKPQSLVSIKCSPHSFFNNLVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEQNNDIASAVQVYSERRVNDAHTINDLAMYNYEELKDLVNKNSYKLRKKFDGFMNAIFPKSWIPLYSMVTFTRIPYSEVVDRRRKQDRILSNLWKTTSTLALIGAAIGIYSN 455
[Close]
BLAST of Kynurenine 3-monooxygenase vs. TrEMBL
Match: A0A1S3JIN9 (Kynurenine 3-monooxygenase OS=Lingula unguis OX=7574 GN=LOC106173625 PE=3 SV=1)

HSP 1 Score: 382.489 bits (981), Expect = 6.417e-125
Identity = 198/412 (48.06%), Postives = 273/412 (66.26%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLV--DVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSILI 1391
            + +++ + E+  DIR      GRSINL+LS RG  ALK VG++E + A  IPMYARM+H  +   K   YG  +Q I ++DR+ +NE LLT+ E +  ++L F+ KLV  +VD  +   K  S K+ H  + D ++G DGA+S VRQ M K+MR +FS+EYIPHGY+ELH PP A+ KH M+   LHIWPR+ +M+I LPN DGSF+  +FMPFE ++ I++ E+L +FF   FPD+  L+G+  L   FF  K   MV+++C PY+     +IMGDAAHAMVPFYGQGMN GFED +IF++IL   + D  +   +FT  RN DA+AMCDLA +NY E+R +V    F LRK +DN +++L P  WIPLYTMV FTR  Y KC+  ++KQD IL R    ++ VL  S+ +
Sbjct:   27 RGFEVDLYERRPDIRTLEHVRGRSINLALSCRGREALKGVGMEEMVTATGIPMYARMIHNTDGTRKPILYGKKDQYIMSVDRRKLNEDLLTEAEKHPGVRLHFSHKLVSCNVDTGEMHFKDASGKDLHTRS-DLIVGCDGAYSAVRQQMMKSMRFDFSQEYIPHGYMELHMPPSANGKHAMETNYLHIWPRNAYMMIALPNQDGSFTVTMFMPFEVFEAIQTEEDLMRFFKEKFPDSLPLLGEQALKETFFNNKALPMVSVKCGPYHHKDKLVIMGDAAHAMVPFYGQGMNCGFEDCLIFNDILDQTNNDFGEALKKFTAYRNVDARAMCDLAMYNYIEMRASVNSKLFLLRKKVDNFLHWLLPDRWIPLYTMVSFTRTRYHKCINGRKKQDMILER--GAVLLVLGSSLFV 435
[Close]
BLAST of Kynurenine 3-monooxygenase vs. TrEMBL
Match: A0A0L8H1W3 (Kynurenine 3-monooxygenase OS=Octopus bimaculoides OX=37653 GN=KMO PE=3 SV=1)

HSP 1 Score: 375.941 bits (964), Expect = 1.767e-122
Identity = 187/391 (47.83%), Postives = 254/391 (64.96%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS--EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDK 1334
            + + + E   DIR      GRSINL+LS RGL+AL  VGL E++    IPMYARM+H  +   +R PYG  NQ I +IDR+ +NE+LLT  E+  N++L F  KL    F  K         KE  E  FD + GNDGA S VR  + K  + +F +++IPHGY+EL  PP  + +  M+  CLHIWPR EFM+I LPNLD SF+  LFMPFE ++ + + ++L  FF   FPD+  LIG+ +L   FF+ K   MVT++C+PYN GG   IMGDAAHAMVPFYGQGMN+GFED I+  + L  +  D D+   ++T+ R+ DA ++CDLA +NY E+R  V    F +RK++DNL+N LFP  WIPLY+MV F+RI Y +C+ +K+ QD+
Sbjct:   30 FKVSLYELRKDIRKEAHVSGRSINLALSERGLSALNEVGLREKVRPFGIPMYARMIHNRDSTKRRIPYGRENQFIMSIDRRKLNELLLTVSESQPNVELHFEHKLKQCSFNGKPKAIFETPSKETVEQDFDVVFGNDGAFSAVRNQIMKTTKFDFQQKFIPHGYMELSIPPNEEGQFAMESNCLHIWPRDEFMMISLPNLDKSFTTTLFMPFELFETLHTKDDLLNFFEKTFPDSLPLIGRKSLVETFFSRKALPMVTVKCHPYNVGGKAAIMGDAAHAMVPFYGQGMNAGFEDCIVMSQFLDEYKNDFDEALPKYTEFRHVDAVSICDLAMYNYVEMRSLVNSKLFLVRKLVDNLLNKLFPHHWIPLYSMVSFSRIRYHECIAKKKWQDQ 420
[Close]
BLAST of Kynurenine 3-monooxygenase vs. TrEMBL
Match: R7TPA4 (Kynurenine 3-monooxygenase OS=Capitella teleta OX=283909 GN=KMO PE=3 SV=1)

HSP 1 Score: 372.474 bits (955), Expect = 4.983e-121
Identity = 188/394 (47.72%), Postives = 256/394 (64.97%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIA-FDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNL-DGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILT 1343
            +D+ + E   DIR      GRSINL+LS RGL ALK VGLDEE+  + IP+++RM+H ++   +   YG  +QCI ++DRK +N +LLT  E N ++ + F  K V  DF+   + F         A  D +IG DGA+S+VR  + K  RM+F + YIPHGYIEL  PP ADNK  M+   LHIWPR+EFM+I LPN+ D SF   LFMPFE ++  ++ E + +FFN  FPD+  LIG+  +   F + KP  +VT++C PY+ G  C+IMGDAAHAMVPFYGQGMN GFED ++F + +   D D  K   E+++ RN DAKAMC+LA +NY E+R +V    F  RK  DN +++L PS W+PLYT V F+++ Y KC+  +  QDKILT
Sbjct:   29 FDVHIHELRPDIRKQELVRGRSINLTLSTRGLEALKAVGLDEEMKQSGIPLHSRMIHDLDGTRRPISYGTKDQCIMSVDRKYLNGLLLTAAERNPSVNIHFEHKFVSCDFQAGTSIFKKPDGSKVTAKSDLIIGCDGAYSSVRHQIMKATRMDFQQAYIPHGYIELRIPPTADNKFAMEVNYLHIWPRNEFMMIALPNVQDNSFVLTLFMPFEIFEAKKTREQVLEFFNKTFPDSIELIGREEIVNTFLSLKPLPLVTVKCQPYHVGDNCVIMGDAAHAMVPFYGQGMNCGFEDCLVFDQFMGKFDNDFAKVLPEYSEYRNPDAKAMCELALYNYTEMRESVNSKFFLARKHFDNFLHWLMPSTWVPLYTSVSFSQMRYHKCIHNRAWQDKILT 422
[Close]
BLAST of Kynurenine 3-monooxygenase vs. TrEMBL
Match: A0A267G5R9 (Kynurenine 3-monooxygenase OS=Macrostomum lignano OX=282301 GN=KMO PE=3 SV=1)

HSP 1 Score: 371.703 bits (953), Expect = 9.446e-121
Identity = 177/396 (44.70%), Postives = 258/396 (65.15%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRL 1349
            + Y++ + E   D R     +GRSINL+LSHRGL AL+ VGL E++  + IPM+ARM+H ++   +  PYG + Q I ++DR  +N +LLT+VE+  NI + F  KLV  D       F ++    +  +D ++G DGA S VR+ M ++ R ++ + YI HGY+E+ FPP     H M    LHIWPR++FMLI LPNLDGSF+G +FMPFE +D+++S E + KF+   FPDA  L+G+  +     + K   +V+IRC PY+     +I+GDAAHAMVPFYGQGMN GFED II  ++++   +D  K    FT +R  DA A+ DLA +NY E+R +V  ++F LRK +DN +N+L P+ W+PLYTMV F+R PY++ + ++  QD++L RL
Sbjct:   27 RGYNVDLFEMRQDFRADATVLGRSINLALSHRGLEALERVGLREKVTKSGIPMHARMIHSLDGKTRPIPYGRTGQFIMSVDRMGLNGVLLTEVESQPNITIHFGHKLVSCDPTTGETVFSTDDSTVKRTYDLIVGCDGAFSAVRKSMMRHCRFDYEQRYIEHGYMEIAFPPSESGGHCMATNYLHIWPRNQFMLIALPNLDGSFTGTMFMPFELFDQLKSPEAVVKFYRDTFPDALELLGEKTVVDTILSLKALPLVSIRCQPYHLNDKMLIIGDAAHAMVPFYGQGMNCGFEDCIILDDLMQQFGHDFGKVLPAFTNSRVEDAHAIVDLALYNYIEMRQSVNSVTFLLRKKLDNALNWLLPNHWVPLYTMVTFSRTPYSRAITDRRWQDRVLGRL 422
[Close]
BLAST of Kynurenine 3-monooxygenase vs. TrEMBL
Match: A0A2C9JJ57 (Kynurenine 3-monooxygenase OS=Biomphalaria glabrata OX=6526 GN=KMO PE=3 SV=1)

HSP 1 Score: 371.318 bits (952), Expect = 1.458e-120
Identity = 193/421 (45.84%), Postives = 275/421 (65.32%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIA--FDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR-LKKMIITVLFGSILI---LTNNLIH 1412
            Y + + E   DIR      G+SINL+LS RG  ALK VGL++ +    IPM+ARM+H +N   +   YG  +Q I +IDR+L+NEI+L+ VE   ++++ F+ KL   +F    A F +E+  H++   FD +IG DGA+S VR+ M K  R ++ + YIPHGY+EL+ PP + N+  M+   LHIWPR+E+M+I LPNLD SF+  LFMPFE ++ I + E L +FF   FPDA  L+G+  L + F ++K   ++T++C+PY+     +++GDAAHAMVPFYGQGMN G ED II  EIL  +D D  K    +TK RN DAKA+CDLA +NY E+R  V   SF +RK +DNL+  +FP  W+PLYTMV FTRI Y + ++ +E QD++LTR L  + IT + G  ++   L+ N +H
Sbjct:   32 YKVDLYEMRPDIRTMKVVRGKSINLALSCRGREALKRVGLEDAVTKYGIPMHARMIHDLNGRRRPILYGTKDQYIMSIDRRLLNEIMLSAVEKFPDVEIHFSHKLTTCNFETGEATFENEQG-HKVTKQFDLIIGCDGAYSAVRKQMMKLSRFDYQQTYIPHGYMELNIPPNSQNEFAMEINYLHIWPRNEYMMIALPNLDKSFTTTLFMPFEMFEAITTEEKLIQFFKEEFPDALPLLGQEELIKTFMSSKALPLITVKCHPYHVNNKAVLLGDAAHAMVPFYGQGMNCGMEDCIILDEILDAYDNDFSKALPAYTKKRNPDAKAICDLAMYNYIEMRSKVNTTSFLIRKKLDNLLFKIFPKTWVPLYTMVSFTRIGYQEAIKRREWQDQVLTRCLTVLGITGVVGLGVMTYQLSQNYVH 451
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Cavefish
Match: kmo (kynurenine 3-monooxygenase [Source:NCBI gene;Acc:103038724])

HSP 1 Score: 320.857 bits (821), Expect = 3.752e-104
Identity = 168/396 (42.42%), Postives = 243/396 (61.36%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS-EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            + +D+ + E   DIR      GRSINL+LSHRG  ALK +G++E+I++  IPM ARM+H ++      PYG   Q I ++ R  +N+ LL+ VE   N +L F+ KL+D         F   +    +   D ++G DGA ST R+   +  R ++S+ YIPHGYIEL  PP  +    M+   LHIWPR+ FM+I LPN+D +F+  LFMPFE +++I + + L  FF  +FPD+  LIG   L R FF      +V ++C+PY+    C++MGDAAHAMVPFYGQGMN+GFED ++F+EI+   + D      EF++ R  D  AMC+LA +NY E+R +V    F  RK +D  +NY+ P   IPLYTM+ FTR  Y + + + + Q+K++TR
Sbjct:   40 RGFDVALFEYREDIRCAKVVKGRSINLALSHRGRQALKHIGIEEKIVSMGIPMRARMIHSLSGKCSPIPYGRKGQYILSVGRANLNKELLSVVETYPNTELNFSHKLLDWSPETGTMTFHGPDGAERDFEADLIVGCDGAFSTTRKQFLRRSRFDYSQTYIPHGYIELTMPP-RNGDFAMEPNFLHIWPRNTFMMIALPNVDKTFTCTLFMPFEDFEKITTGDELIAFFQKHFPDSIPLIGVEALKRDFFLLPAQALVWVKCSPYHMLDRCVLMGDAAHAMVPFYGQGMNAGFEDCLVFNEIMDQFNEDFAAVLPEFSRVRAPDDHAMCELAMYNYIEMRSHVNSRYFLFRKYLDGALNYIMPKTIIPLYTMITFTRTRYHEAVIQWQWQNKVITR 434
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Cavefish
Match: kmo (kynurenine 3-monooxygenase [Source:NCBI gene;Acc:103038724])

HSP 1 Score: 307.76 bits (787), Expect = 1.353e-99
Identity = 168/398 (42.21%), Postives = 241/398 (60.55%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMN--EIL--LTKVENNENIQLFFNMKLVDVDFRKKIAKFLS-EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR 1346
            +D+ + E   DIR      GRSINL+LSHRG  ALK +G++E+I++  IPM ARM+H ++      PYG   Q +  +  KL N  ++L  L  VE   N +L F+ KL+D         F   +    +   D ++G DGA ST R+   +  R ++S+ YIPHGYIEL  PP  +    M+   LHIWPR+ FM+I LPN+D +F+  LFMPFE +++I + + L  FF  +FPD+  LIG   L R FF      +V ++C+PY+    C++MGDAAHAMVPFYGQGMN+GFED ++F+EI+   + D      EF++ R  D  AMC+LA +NY E+R +V    F  RK +D  +NY+ P   IPLYTM+ FTR  Y + + + + Q+K++TR
Sbjct:    2 FDVALFEYREDIRCAKVVKGRSINLALSHRGRQALKHIGIEEKIVSMGIPMRARMIHSLSGKCSPIPYGRKGQ-VKPLFVKLANPYQVLGALKMVETYPNTELNFSHKLLDWSPETGTMTFHGPDGAERDFEADLIVGCDGAFSTTRKQFLRRSRFDYSQTYIPHGYIELTMPP-RNGDFAMEPNFLHIWPRNTFMMIALPNVDKTFTCTLFMPFEDFEKITTGDELIAFFQKHFPDSIPLIGVEALKRDFFLLPAQALVWVKCSPYHMLDRCVLMGDAAHAMVPFYGQGMNAGFEDCLVFNEIMDQFNEDFAAVLPEFSRVRAPDDHAMCELAMYNYIEMRSHVNSRYFLFRKYLDGALNYIMPKTIIPLYTMITFTRTRYHEAVIQWQWQNKVITR 397
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Sea Lamprey
Match: KMO (kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc:HGNC:6381])

HSP 1 Score: 203.756 bits (517), Expect = 9.755e-63
Identity = 108/236 (45.76%), Postives = 155/236 (65.68%), Query Frame = 3 
Query:  696 MDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR--LKKMIITVLFGSILILT 1397
            M+K  LHIWPR+ FM+I LPN D SF+  LFMPFE ++ I   E++  FF+  FPDA  LIG + L R FF      +V+I+C+PY+ G   +IMGDAAHAMVPFYGQGMN+GFED ++F E+++  + DL +   EF++ R  D +A+ DLA +NY E+R +V    F  RK +DNL+  L P  ++PLYTMV FTRI Y + +++ + Q+K++    L   +++VL     + T
Sbjct:    3 MEKNYLHIWPRNTFMMIALPNNDHSFTCTLFMPFEEFECITEPEHVLDFFSRYFPDAIPLIGAAELQRDFFLLPAQALVSIKCSPYHVGRRVVIMGDAAHAMVPFYGQGMNAGFEDCLVFDELMEEFNCDLGRVLPEFSRLRTPDDQAIVDLAMYNYIEMRAHVNSRWFLFRKRVDNLLYLLMPGTFVPLYTMVTFTRIRYHEVVKKCKLQNKVVNSALLGIGVLSVLSAGAWVAT 238
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Yeast
Match: BNA4 (Kynurenine 3-monooxygenase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; putative therapeutic target for Huntington disease [Source:SGD;Acc:S000000194])

HSP 1 Score: 252.677 bits (644), Expect = 4.710e-79
Identity = 157/398 (39.45%), Postives = 227/398 (57.04%), Query Frame = 3 
Query:  228 RSINLSLSHRGLTALKIVGLD--EEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFR--KKIAKF-LSE--KEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNK------HVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILF-MPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNF-GGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCF-TRIPYTKCLEEKEKQDKILTRLKKMIITVL 1373
            +SINL++S RG+ ALK +  D  E IL   IPM  RM+H +    +   YGL  + I++I+R ++N  LL ++E +   +L F  KLV +++   K+I  F + E  K  H   +DF+IG DGA+S  R  M + + M+FS+EY+   YIEL+ PP  + K        +    LHIWPR +FMLI L N DGSF+   F    +  D I S   + +F   NFPD   ++   +  + F       +V + C PY+  GG  I++GDAAHAMVPFYGQGMN GFEDV I   +LK H  D  +   E+T+ R+ D  ++ +LA  NY E+  +VT   F LRK +D L + +    WIPLYTM+ F + I Y++ LE   KQ +IL  L+ + + +L
Sbjct:   48 KSINLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYGLHGEAINSINRSVLNNSLLDELEKS-TTELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGNFAIAPDHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESLVCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTEYTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKLDALFSIIMKDKWIPLYTMISFRSDISYSRALERAGKQTRILKFLESLTLGML 444
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Nematostella
Match: EDO45190 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTD3])

HSP 1 Score: 327.791 bits (839), Expect = 3.731e-108
Identity = 171/394 (43.40%), Postives = 247/394 (62.69%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKK--IAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKI 1337
            + Y + + E   D R       RSINL+LS RG++AL  VG +  ++ + IPM+ARM+H +       PYG   Q I +++R+ MNE LLT  E++ N+ L F  KL  VD  K     K  S  E  ++  D L+G DGA+S VR+ + +  R ++S+EYIPHGY E+  PP A+ KH+M+   LHIWPR+ FM+I LPN DG+F+  LF PF+ +D+I++N+++  FFN  FPD   LIG+  L   +F      MV+++C PY+     +I+GDAAHAMVPFYGQGMN GFED ++ +EIL  H+ +L     E++  RN DA+AMCDLA +NY E+R +V    F ++K   + +++L P   IPLYTMV F+RIPY   ++  + QD +
Sbjct:   12 RGYKVDLYESRQDPRKLQFVSLRSINLALSVRGISALAAVGCERPMVESGIPMHARMIHTLKGSKYAIPYGKKGQYIMSVERRKMNEHLLTVAESHPNVTLHFGHKLKKVDVEKAHMTYKTSSAGEVVDVDADLLVGCDGAYSAVRKEIMRRPRFDYSQEYIPHGYKEICLPPDANGKHIMELNYLHIWPRNTFMMIALPNQDGTFTCTLFAPFDTFDKIKTNDDVLNFFNKEFPDFIPLIGEEKLLSDWFTNPVGSMVSVKCKPYHVADKVVILGDAAHAMVPFYGQGMNCGFEDCLVLNEILDKHNDNLGAALEEYSMLRNPDAEAMCDLAMYNYIEMRSSVNSTLFLVKKYFFSFLHWLMPKTIIPLYTMVTFSRIPYHTVIKRSKLQDNV 405
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Nematostella
Match: EDO43899 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX40])

HSP 1 Score: 284.263 bits (726), Expect = 1.470e-90
Identity = 154/397 (38.79%), Postives = 225/397 (56.68%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS---EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRL 1349
            Y + + E   D R       RSINL+LSHRG+ AL +VG DE++L  S+ M AR +H  N       YG + +CI +++R+ +NE LL   E+  N+   F  KL   D     A F+    +     +  D L+G DGA S +R+ M    R ++S+ YIPH Y E+  PP  D +  ++   LHIWPR+ FM+I   N D SF+  LF P+E+++ I + E++  FFN  FPD    + + N            ++ + C+PY++    +I+GDAAHAMVPFY QGMN GFED ++  E+L  H  D+     E+T  RN D KA+CDLA +NY E+R +VT   F  R+ +  L++  FP   +PLYTMV F+RIPY + +    +QD+I+  L
Sbjct:   56 YRVDIYEARKDPRLVKTVSQRSINLALSHRGIAALAVVGCDEQLLEDSVAMSARYIHARNRQTYSMQYGTNGECIYSVERRKVNEFLLNVAESYMNVTFHFEHKLRSADL--DCASFICTSPDGSALRVNADLLVGCDGAFSALRREMMARTRFDYSQAYIPHWYKEISLPPRPDGEPHIEPSYLHIWPRTSFMMIAQANKDNSFTCTLFAPYEHFERINTKEDVLGFFNSEFPDFMDHLEEVNSDHSSNHFCHLGLILLPCSPYHYKDKAVILGDAAHAMVPFYAQGMNCGFEDCLVLDELLVKHKKDIGAALSEYTSVRNPDGKAICDLAMYNYTEMRSSVTSKIFIWRRTLYLLLHKCFPRLLLPLYTMVTFSRIPYHEVIIRTRRQDRIVNIL 450
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Nematostella
Match: EDO45186 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTC7])

HSP 1 Score: 248.825 bits (634), Expect = 1.560e-78
Identity = 140/345 (40.58%), Postives = 199/345 (57.68%), Query Frame = 3 
Query:  162 QKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLL 1196
            + Y + + E   D R       RSINL+LS RG++AL  VG +  ++ + IPM+ARM+H +       PYG   Q ISA                          ++VDVD                   D L+G DGA+S VR+ + +  R ++S+EYIPHGY E+  PP A+ KH+M+   LHIWPR+ FM+I LPN DG+F+  LF PF+ +DEI++N+++  FFN  FPD   LIG+  L   +F      MV+++C PY+     +I+GDAAHAMVPFYGQGMN GFED ++ +EIL  H+ +L     E++  RN DA+AMCDLA +NY E+ I + ++
Sbjct:   33 RGYKVDLYESRQDPRKLQFVSLRSINLALSVRGISALAAVGCERPMVESGIPMHARMIHTLKGSKYAIPYGKKGQ-ISA-------------------------GEVVDVDA------------------DLLVGCDGAYSAVRKEIMRRPRFDYSQEYIPHGYKEICLPPDANGKHIMELNYLHIWPRNTFMMIALPNQDGTFTCTLFAPFDTFDEIKTNDDVLNFFNKEFPDFIPLIGEEKLLSDWFTNPVGAMVSVKCKPYHVADKVVILGDAAHAMVPFYGQGMNCGFEDCLVLNEILDKHNDNLGAALEEYSMVRNPDAEAMCDLAMYNYIEVSIMLMMI 333
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Nematostella
Match: EDO26830 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAY7])

HSP 1 Score: 226.868 bits (577), Expect = 2.682e-69
Identity = 134/359 (37.33%), Postives = 206/359 (57.38%), Query Frame = 3 
Query:  318 MYARMVHGVNEDLKRFPY-GLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFD--FLIGNDGAHSTVRQ--FMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEY----YDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVE-----FTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTR-IPYTKCLEEKEKQDKILTRL 1349
            MY R++H + E+     Y G +N+ I++I R  +N ILLT+ E ++N+ + FN K   VD    IA F ++K   E A D   + G DGA S +R+  ++ K    ++S++Y+ HGY EL  P  A+  H + K  LHIWPR ++MLI LPN+DGSF+  LF+  E     + E++S E +  FF   FPDA  LI   N+A  F       + T++C+P+ +    +IMGDAAHA+VPFYGQGMN+ FEDV++F EIL + +   +    E     + K R  +A A+ DLA  NY E+R +V    F+ +++++  +   FP+ +   Y+MV F   + Y + + +   QDK L  +
Sbjct:    1 MYGRLIHDLEENTFASNYSGRANEYINSISRGDLNGILLTEAEKHKNVTIHFNTKCSSVDIENTIAHFKNDKTNEEFAIDADVIFGTDGAGSVLRKSYYLEKKFLFSYSQDYLTHGYKELEIPADANGNHQLSKDHLHIWPRGDYMLIALPNMDGSFTVTLFLGHEEGTYNFKELDSEEKIKNFFKKQFPDALILI--PNIADEFVNNPTGALGTVKCSPWYYKSNTMIMGDAAHAVVPFYGQGMNASFEDVVVFDEILNHFERSPEINSWETVFKAYEKARKANADAIGDLAVENYYEMRDHVANPLFKQKRMLEMELEKNFPTAYFSKYSMVTFNEDMGYHEAMVKGRAQDKALLNM 357
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Medaka
Match: kmo (kynurenine 3-monooxygenase [Source:NCBI gene;Acc:101158471])

HSP 1 Score: 330.872 bits (847), Expect = 4.583e-108
Identity = 176/423 (41.61%), Postives = 255/423 (60.28%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKF-LSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR--LKKMIITVLFGSILILTNNLIHNKFAI 1427
            +++ V E   DIR      GRSINL+LSHRG  ALK VG++++I++  IPM+ARM+H ++      PYG   Q I ++DR  +N+ LL++ E   N  L F  KL D      +  F  S+    +I  D ++G DGA S  R+   +  R N+S+ YIPHGY+EL  PP  + +  M    LHIWPR+ FM+I LPNLD +F+  LFMPFE +++I + + + +FF   FPD   LIG   L + +F      MV+++C+PY+ G  C++MGDAAHA+VPFYGQGMN+GFED I+F E+++  + D      E+T+ R  D  A+ DLA +NY E+R +V    F  RK +DN++++  P   IPLYTMV FTRIPY   +E    Q+K++    L   +  VL GS L+  ++   N  A+
Sbjct:   35 FNVHVFESREDIRKAKIVKGRSINLALSHRGRQALKHVGMEDKIISKGIPMHARMIHSLSGKQSPIPYGRKGQYILSVDRANLNKELLSEAETYPNTTLNFEHKLQDWSADTGLMTFSRSDGSKDQIHADLIVGCDGAFSATRKQFLRRSRFNYSQTYIPHGYMELTMPP-VNGEFAMKPNYLHIWPRNTFMMIALPNLDKTFTCTLFMPFEDFEKITTGDEVIQFFQSYFPDTIPLIGVEALKKDYFRLPAQAMVSVKCSPYHIGDKCVLMGDAAHAVVPFYGQGMNAGFEDCIVFDELMEQFNEDFCAVLPEYTRVRVPDDHAIADLAMYNYVEMRAHVNSKWFLFRKYVDNVLHFFLPKTIIPLYTMVTFTRIPYHHAVERWHWQNKVINYGLLLSAVGAVLGGSYLLTKHSQQVNNLAV 456
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Medaka
Match: kmo (kynurenine 3-monooxygenase [Source:NCBI gene;Acc:101158471])

HSP 1 Score: 330.487 bits (846), Expect = 1.273e-107
Identity = 176/423 (41.61%), Postives = 255/423 (60.28%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKF-LSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR--LKKMIITVLFGSILILTNNLIHNKFAI 1427
            +++ V E   DIR      GRSINL+LSHRG  ALK VG++++I++  IPM+ARM+H ++      PYG   Q I ++DR  +N+ LL++ E   N  L F  KL D      +  F  S+    +I  D ++G DGA S  R+   +  R N+S+ YIPHGY+EL  PP  + +  M    LHIWPR+ FM+I LPNLD +F+  LFMPFE +++I + + + +FF   FPD   LIG   L + +F      MV+++C+PY+ G  C++MGDAAHA+VPFYGQGMN+GFED I+F E+++  + D      E+T+ R  D  A+ DLA +NY E+R +V    F  RK +DN++++  P   IPLYTMV FTRIPY   +E    Q+K++    L   +  VL GS L+  ++   N  A+
Sbjct:   30 FNVHVFESREDIRKAKIVKGRSINLALSHRGRQALKHVGMEDKIISKGIPMHARMIHSLSGKQSPIPYGRKGQYILSVDRANLNKELLSEAETYPNTTLNFEHKLQDWSADTGLMTFSRSDGSKDQIHADLIVGCDGAFSATRKQFLRRSRFNYSQTYIPHGYMELTMPP-VNGEFAMKPNYLHIWPRNTFMMIALPNLDKTFTCTLFMPFEDFEKITTGDEVIQFFQSYFPDTIPLIGVEALKKDYFRLPAQAMVSVKCSPYHIGDKCVLMGDAAHAVVPFYGQGMNAGFEDCIVFDELMEQFNEDFCAVLPEYTRVRVPDDHAIADLAMYNYVEMRAHVNSKWFLFRKYVDNVLHFFLPKTIIPLYTMVTFTRIPYHHAVERWHWQNKVINYGLLLSAVGAVLGGSYLLTKHSQQVNNLAV 451
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Medaka
Match: kmo (kynurenine 3-monooxygenase [Source:NCBI gene;Acc:101158471])

HSP 1 Score: 317.775 bits (813), Expect = 2.801e-103
Identity = 170/422 (40.28%), Postives = 253/422 (59.95%), Query Frame = 3 
Query:  168 YDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTR--LKKMIITVLFGSILILTNNLIHNKFAI 1427
            +++ V E   DIR      GRSINL+LSHRG  ALK VG++++I++  IPM+ARM+H ++      PYG   Q I ++DR  +N+ LL+     ++ +        D++ R+      S+    +I  D ++G DGA S  R+   +  R N+S+ YIPHGY+EL  PP  + +  M    LHIWPR+ FM+I LPNLD +F+  LFMPFE +++I + + + +FF   FPD   LIG   L + +F      MV+++C+PY+ G  C++MGDAAHA+VPFYGQGMN+GFED I+F E+++  + D      E+T+ R  D  A+ DLA +NY E+R +V    F  RK +DN++++  P   IPLYTMV FTRIPY   +E    Q+K++    L   +  VL GS L+  ++   N  A+
Sbjct:   35 FNVHVFESREDIRKAKIVKGRSINLALSHRGRQALKHVGMEDKIISKGIPMHARMIHSLSGKQSPIPYGRKGQYILSVDRANLNKELLSGKRRQKDAE--------DLNDRR------SDGSKDQIHADLIVGCDGAFSATRKQFLRRSRFNYSQTYIPHGYMELTMPP-VNGEFAMKPNYLHIWPRNTFMMIALPNLDKTFTCTLFMPFEDFEKITTGDEVIQFFQSYFPDTIPLIGVEALKKDYFRLPAQAMVSVKCSPYHIGDKCVLMGDAAHAVVPFYGQGMNAGFEDCIVFDELMEQFNEDFCAVLPEYTRVRVPDDHAIADLAMYNYVEMRAHVNSKWFLFRKYVDNVLHFFLPKTIIPLYTMVTFTRIPYHHAVERWHWQNKVINYGLLLSAVGAVLGGSYLLTKHSQQVNNLAV 441
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Planmine SMEST
Match: SMESG000055918.1 (SMESG000055918.1)

HSP 1 Score: 861.292 bits (2224), Expect = 0.000e+0
Identity = 451/451 (100.00%), Postives = 451/451 (100.00%), Query Frame = 3 
Query:   75 MTSENKRPKXXXXXXXXXXXXXXXXXXRTQKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSILILTNNLIHNKFAI 1427
            MTSENKRPKVLIVGGGLVGALNALFFARTQKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESNENLFKFFNFNFPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSILILTNNLIHNKFAI
Sbjct:    1 MTSENKRPKVLIVGGGLVGALNALFFARTQKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESNENLFKFFNFNFPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSILILTNNLIHNKFAI 451
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Planmine SMEST
Match: SMESG000055705.1 (SMESG000055705.1)

HSP 1 Score: 525.783 bits (1353), Expect = 0.000e+0
Identity = 255/417 (61.15%), Postives = 329/417 (78.90%), Query Frame = 3 
Query:  165 KYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEI--AFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSILILTNNLI 1409
            K+++ + EK+ D R  ++ +GR+INLSLS+RGL ALKIV L+EE+L   IPMYARM+H  +  LKRF YG S+QCI A++R+++  ILL K E +++IQ+ FN KL DV+F +KIAKF + K   +I   FD L+GNDGA+S VR  M+KN+RM+FS+EYIPHGYIE+ FPP   NKH MDK CLHIWPR+E+ML  LPNL+GSFSG LFMPF+ ++ I S ++L + F   FPDA  +IGK +L  +F  +K +KMVTIRCNPYN G  C+IMGDAAHAMVPFYGQGMNSGFEDV IFHEIL+ +D++L KTC +F++ RN DAKAMC+LA +NY ELR NVT+LSFR+RK+ DNLMN LFPS+WIPLYTMVCF+RIPY KC+EEK+KQDKIL+R++ + I V+ GSI+I  N ++
Sbjct:   31 KFNVTIYEKSPDNRTIHQDVGRNINLSLSYRGLLALKIVDLEEEVLKKCIPMYARMIHERSGPLKRFFYGKSSQCIFAMERRVLLNILLAKAEIHKSIQINFNTKLYDVNFNEKIAKFKNLKNMEDIEKKFDLLVGNDGAYSHVRHIMTKNLRMDFSQEYIPHGYIEMPFPPVDGNKHSMDKNCLHIWPRNEYMLTALPNLNGSFSGTLFMPFKMFESIHSKKDLLELFEKEFPDALEIIGKLHLCDLFQKSKLSKMVTIRCNPYNLGEKCVIMGDAAHAMVPFYGQGMNSGFEDVTIFHEILQKNDFNLGKTCNDFSEKRNNDAKAMCELASYNYLELRKNVTMLSFRMRKMFDNLMNSLFPSYWIPLYTMVCFSRIPYMKCVEEKQKQDKILSRIQSLSIGVMLGSIIIGINRIL 447
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BLAST of Kynurenine 3-monooxygenase vs. Planmine SMEST
Match: SMESG000055694.1 (SMESG000055694.1)

HSP 1 Score: 522.702 bits (1345), Expect = 0.000e+0
Identity = 263/423 (62.17%), Postives = 341/423 (80.61%), Query Frame = 3 
Query:   75 MTSENKRPKXXXXXXXXXXXXXXXXXXRTQKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILT 1343
            M+  NKRPKV+IVGGGLVGALNA+FF++T ++D+++CEK SDIR     +GRSINLSLSHRG  AL+ VGL+E IL +SI MYARM+H  + +LKR PYG  N+  +A+DRK++NE+LLT+ E+N+N+ + F  KLVDVD +K+IAKF + K   EI +D L+GNDGA+STVRQ MSK +R +FS+E+I HGY EL+FPPGAD+  +MD  CLHIWPR+EFMLIGLPN  GSF+G LFMPFE +++I++ + L  FF+  FPDA  L+GKSNL +++F+   + MVTI+CNPYNF   C+IMGDAAHAMVPFYGQGMN GFED++IFHEILK ++Y L+ TC EFT+ RN DAK +CDLAF+NY E+R +V+  SF +RK  DNLMN+LFPSFW+PLY+MV FTRIPY+ CL+E++KQD+ILT
Sbjct:    2 MSESNKRPKVVIVGGGLVGALNAVFFSKTDQFDVLLCEKRSDIRMDTEHVGRSINLSLSHRGREALRAVGLEENILKSSIRMYARMIHDTHGNLKRIPYGRPNEFNNAVDRKVLNELLLTEAESNKNVTIKFGCKLVDVDLQKRIAKFSNGKFIEEIQYDLLVGNDGAYSTVRQLMSKGLRFDFSQEFISHGYKELYFPPGADDTFLMDMNCLHIWPRNEFMLIGLPNPGGSFTGTLFMPFEIFNKIKTKDELLTFFSKYFPDALELMGKSNLEKVYFSRTASSMVTIKCNPYNFEESCVIMGDAAHAMVPFYGQGMNCGFEDLLIFHEILKENNYKLENTCSEFTERRNRDAKTICDLAFYNYVEMRKSVSSKSFLIRKKFDNLMNFLFPSFWVPLYSMVSFTRIPYSLCLKERKKQDRILT 424
[Close]
BLAST of Kynurenine 3-monooxygenase vs. Planmine SMEST
Match: SMESG000055694.1 (SMESG000055694.1)

HSP 1 Score: 522.702 bits (1345), Expect = 0.000e+0
Identity = 263/423 (62.17%), Postives = 341/423 (80.61%), Query Frame = 3 
Query:   75 MTSENKRPKXXXXXXXXXXXXXXXXXXRTQKYDIIVCEKTSDIRGTNRTIGRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYGLSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLSEKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPPGADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESXXXXXXXXXXXXPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCIIMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRNFDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTMVCFTRIPYTKCLEEKEKQDKILT 1343
            M+  NKRPKV+IVGGGLVGALNA+FF++T ++D+++CEK SDIR     +GRSINLSLSHRG  AL+ VGL+E IL +SI MYARM+H  + +LKR PYG  N+  +A+DRK++NE+LLT+ E+N+N+ + F  KLVDVD +K+IAKF + K   EI +D L+GNDGA+STVRQ MSK +R +FS+E+I HGY EL+FPPGAD+  +MD  CLHIWPR+EFMLIGLPN  GSF+G LFMPFE +++I++ + L  FF+  FPDA  L+GKSNL +++F+   + MVTI+CNPYNF   C+IMGDAAHAMVPFYGQGMN GFED++IFHEILK ++Y L+ TC EFT+ RN DAK +CDLAF+NY E+R +V+  SF +RK  DNLMN+LFPSFW+PLY+MV FTRIPY+ CL+E++KQD+ILT
Sbjct:    1 MSESNKRPKVVIVGGGLVGALNAVFFSKTDQFDVLLCEKRSDIRMDTEHVGRSINLSLSHRGREALRAVGLEENILKSSIRMYARMIHDTHGNLKRIPYGRPNEFNNAVDRKVLNELLLTEAESNKNVTIKFGCKLVDVDLQKRIAKFSNGKFIEEIQYDLLVGNDGAYSTVRQLMSKGLRFDFSQEFISHGYKELYFPPGADDTFLMDMNCLHIWPRNEFMLIGLPNPGGSFTGTLFMPFEIFNKIKTKDELLTFFSKYFPDALELMGKSNLEKVYFSRTASSMVTIKCNPYNFEESCVIMGDAAHAMVPFYGQGMNCGFEDLLIFHEILKENNYKLENTCSEFTERRNRDAKTICDLAFYNYVEMRKSVSSKSFLIRKKFDNLMNFLFPSFWVPLYSMVSFTRIPYSLCLKERKKQDRILT 423
The following BLAST results are available for this feature:
BLAST of Kynurenine 3-monooxygenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
KMO6.150e-10039.90kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc... [more]
KMO3.249e-9539.14kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc... [more]
KMO3.409e-8641.00kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc... [more]
KMO5.299e-1635.78kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
kmo-12.939e-10541.13Kynurenine 3-monooxygenase [Source:UniProtKB/Swis... [more]
kmo-21.682e-4427.58Kynurenine 3-MonoOxygenase [Source:UniProtKB/TrEM... [more]
kmo-22.188e-4327.36Kynurenine 3-MonoOxygenase [Source:UniProtKB/TrEM... [more]
kmo-22.188e-4327.36Kynurenine 3-MonoOxygenase [Source:UniProtKB/TrEM... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cn7.782e-9943.85gene:FBgn0000337 transcript:FBtr0344723[more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
kmo3.845e-10844.42kynurenine 3-monooxygenase [Source:NCBI gene;Acc:3... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
bend31.367e-10544.78BEN domain containing 3 [Source:Xenbase;Acc:XB-GEN... [more]
bend33.852e-10544.76BEN domain containing 3 [Source:Xenbase;Acc:XB-GEN... [more]
bend37.023e-9241.60BEN domain containing 3 [Source:Xenbase;Acc:XB-GEN... [more]
bend37.486e-8641.67BEN domain containing 3 [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Kmo3.379e-10340.40kynurenine 3-monooxygenase (kynurenine 3-hydroxyla... [more]
Kmo2.093e-8739.34kynurenine 3-monooxygenase (kynurenine 3-hydroxyla... [more]
Kmo4.196e-3538.12kynurenine 3-monooxygenase (kynurenine 3-hydroxyla... [more]
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BLAST of Kynurenine 3-monooxygenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q86PM2|KMO_AEDAE6.538e-11345.27Kynurenine 3-monooxygenase OS=Aedes aegypti OX=715... [more]
sp|Q7Q6A7|KMO_ANOGA1.737e-11044.15Kynurenine 3-monooxygenase OS=Anopheles gambiae OX... [more]
sp|Q1RLY6|KMO_DANRE7.740e-10744.42Kynurenine 3-monooxygenase OS=Danio rerio OX=7955 ... [more]
sp|Q6DIZ8|KMO_XENTR7.240e-10544.78Kynurenine 3-monooxygenase OS=Xenopus tropicalis O... [more]
sp|A8Y432|KMO_CAEBR8.095e-10541.24Kynurenine 3-monooxygenase OS=Caenorhabditis brigg... [more]
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BLAST of Kynurenine 3-monooxygenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JIN96.417e-12548.06Kynurenine 3-monooxygenase OS=Lingula unguis OX=75... [more]
A0A0L8H1W31.767e-12247.83Kynurenine 3-monooxygenase OS=Octopus bimaculoides... [more]
R7TPA44.983e-12147.72Kynurenine 3-monooxygenase OS=Capitella teleta OX=... [more]
A0A267G5R99.446e-12144.70Kynurenine 3-monooxygenase OS=Macrostomum lignano ... [more]
A0A2C9JJ571.458e-12045.84Kynurenine 3-monooxygenase OS=Biomphalaria glabrat... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
kmo3.752e-10442.42kynurenine 3-monooxygenase [Source:NCBI gene;Acc:1... [more]
kmo1.353e-9942.21kynurenine 3-monooxygenase [Source:NCBI gene;Acc:1... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
KMO9.755e-6345.76kynurenine 3-monooxygenase [Source:HGNC Symbol;Acc... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
BNA44.710e-7939.45Kynurenine 3-monooxygenase; required for the de no... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO451903.731e-10843.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO438991.470e-9038.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO451861.560e-7840.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO268302.682e-6937.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
kmo4.583e-10841.61kynurenine 3-monooxygenase [Source:NCBI gene;Acc:1... [more]
kmo1.273e-10741.61kynurenine 3-monooxygenase [Source:NCBI gene;Acc:1... [more]
kmo2.801e-10340.28kynurenine 3-monooxygenase [Source:NCBI gene;Acc:1... [more]
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BLAST of Kynurenine 3-monooxygenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000055918.10.000e+0100.00SMESG000055918.1[more]
SMESG000055705.10.000e+061.15SMESG000055705.1[more]
SMESG000055694.10.000e+062.17SMESG000055694.1[more]
SMESG000055694.10.000e+062.17SMESG000055694.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016169 ID=SMED30016169|Name=Kynurenine 3-monooxygenase|organism=Schmidtea mediterranea sexual|type=transcript|length=1514bp
GTTGAGTCAAGTGCGATTTCTTTATAGACGTACGCATAGAGATACGGCAT
TCATTGTCTAAATAGAAGTTCAACATGACAAGCGAAAACAAACGACCCAA
AGTTTTGATTGTTGGTGGAGGTCTGGTAGGAGCTTTAAATGCATTATTTT
TTGCACGGACTCAGAAATATGACATTATAGTGTGTGAGAAGACATCAGAC
ATTCGAGGCACGAACCGAACAATCGGACGAAGTATCAACCTGTCTTTATC
GCACAGGGGTTTAACTGCTTTAAAAATTGTTGGTTTAGACGAAGAGATAC
TTGCAGCATCAATTCCAATGTATGCGAGAATGGTTCATGGTGTTAACGAA
GACCTGAAACGGTTTCCTTATGGTTTATCAAATCAATGTATTTCGGCAAT
AGACAGAAAGTTGATGAATGAAATCCTTTTGACCAAAGTCGAAAACAACG
AAAACATTCAACTTTTCTTTAATATGAAACTTGTAGATGTTGATTTTCGT
AAAAAAATCGCGAAATTTCTTAGTGAAAAAGAATATCATGAAATCGCTTT
TGACTTTCTTATTGGAAATGATGGAGCTCATTCAACAGTTCGTCAGTTTA
TGTCTAAAAATATGAGAATGAACTTTTCAGAGGAATATATTCCCCACGGA
TATATTGAATTACATTTTCCTCCAGGAGCAGACAATAAACATGTAATGGA
TAAAAAGTGCCTCCATATCTGGCCTCGCAGTGAATTCATGTTGATAGGGT
TGCCTAACCTTGATGGATCATTTTCCGGAATCTTATTTATGCCTTTTGAA
TATTATGATGAAATCGAATCCAATGAGAATTTATTTAAATTTTTTAATTT
CAATTTTCCAGACGCTTTTCGACTTATTGGGAAATCAAATTTGGCTCGTA
TGTTTTTTGCCACCAAACCGGCCAAAATGGTCACTATTCGTTGTAATCCA
TACAATTTTGGTGGGCTATGCATAATTATGGGAGATGCTGCTCATGCCAT
GGTTCCTTTCTACGGTCAAGGCATGAACTCGGGATTTGAAGATGTCATTA
TTTTCCATGAAATCCTAAAGAATCATGATTACGATTTAGATAAAACTTGC
GTTGAATTCACCAAAAACAGGAACTTTGATGCAAAAGCTATGTGTGACTT
AGCATTTTTCAATTATGATGAACTACGGATAAATGTCACTTTGCTATCTT
TTCGCTTGAGAAAGATAATTGATAATTTGATGAATTATTTGTTTCCGTCT
TTTTGGATACCTCTATATACAATGGTTTGCTTTACGCGCATCCCGTATAC
AAAATGTTTAGAAGAAAAGGAAAAACAAGACAAAATTCTGACGAGACTGA
AGAAAATGATAATAACAGTACTTTTTGGCAGCATTTTGATTTTGACAAAT
AATTTAATTCATAATAAATTTGCGATATAAACATTTATTTATTATTATCG
CTATTTTTCATGAACAATAAATGTCAATTTGTCTCTCTAAATTATATTTG
TTTTAATGTTTAGG
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protein sequence of SMED30016169-orf-1

>SMED30016169-orf-1 ID=SMED30016169-orf-1|Name=SMED30016169-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=452bp
MTSENKRPKVLIVGGGLVGALNALFFARTQKYDIIVCEKTSDIRGTNRTI
GRSINLSLSHRGLTALKIVGLDEEILAASIPMYARMVHGVNEDLKRFPYG
LSNQCISAIDRKLMNEILLTKVENNENIQLFFNMKLVDVDFRKKIAKFLS
EKEYHEIAFDFLIGNDGAHSTVRQFMSKNMRMNFSEEYIPHGYIELHFPP
GADNKHVMDKKCLHIWPRSEFMLIGLPNLDGSFSGILFMPFEYYDEIESN
ENLFKFFNFNFPDAFRLIGKSNLARMFFATKPAKMVTIRCNPYNFGGLCI
IMGDAAHAMVPFYGQGMNSGFEDVIIFHEILKNHDYDLDKTCVEFTKNRN
FDAKAMCDLAFFNYDELRINVTLLSFRLRKIIDNLMNYLFPSFWIPLYTM
VCFTRIPYTKCLEEKEKQDKILTRLKKMIITVLFGSILILTNNLIHNKFA
I*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000419prepharyngeal region
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR023753FAD/NAD-binding_dom
IPR002938FAD-bd
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0043420anthranilate metabolic process
GO:0006569tryptophan catabolic process
GO:0009435NAD biosynthetic process
GO:0019363pyridine nucleotide biosynthetic process
GO:0019805quinolinate biosynthetic process
GO:0034354'de novo' NAD biosynthetic process from tryptophan
Vocabulary: molecular function
TermDefinition
GO:0016491oxidoreductase activity
GO:0071949FAD binding
GO:0050660flavin adenine dinucleotide binding
GO:0004497monooxygenase activity
GO:0004502kynurenine 3-monooxygenase activity
Vocabulary: cellular component
TermDefinition
GO:0005739mitochondrion