Protein kinase N2

Overview


Name	Protein kinase N2
Smed ID	SMED30016165
Length (bp)	3596

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein kinase N2 (SMED30016165) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase N2 (SMED30016165) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase N2 (SMED30016165) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase N2 (SMED30016165) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016165

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
neoblast	SMED30016165	SMESG000036540.1 SMESG000065035.1	dd_Smed_v4_1180_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30016165	SMESG000036540.1 SMESG000065035.1	dd_Smed_v4_1180_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30016165	SMESG000036540.1 SMESG000065035.1	dd_Smed_v4_1180_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN2 (protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406])

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 373/887 (42.05%), Postives = 528/887 (59.53%), Query Frame = 3

Query:  330 DPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDD----SLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISP---------------PTMPAPNSD---------FSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQ--FQHSTQKS--EYAVMQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            DP    S   LK L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + ++P N   S+I  ++    + S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN  V +T ++ IS+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP               P +  P SD                  PR S   +ID +   ++L  L I     P  + +       D  ++  + Q  ++  T +S  EY+ +Q ++    +R+ ++  +N  +FRC +VLGRGHFGKVLLA+YK+  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR +++  L+ K+VKP F+P +   EDVSNFD EFT E PILTP ++  +L+E +Q+
Sbjct:  128 DPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDES---SELRVLDI-----PGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELE---DRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQE 972

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN1 (protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 353/849 (41.58%), Postives = 499/849 (58.78%), Query Frame = 3

Query:  354 TSLKNLEHRLAIEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN--DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMK---PIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLG--------FSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQER--PQFQHSTQKSEY-AVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            + +  LE +LAIE+ V+ GAE ++Q +  G  KD       +++ ++SK KI  I  Q+ R     +  +EN     D   + +   +E+ I  L++   +E A+  G    LR + A    DR    +      ES QK+ L ++++++ + +LP+      D     L++          FS +RL     A   S L   + ++GTL +  +GC+DL ++ P N   +    G         S  +  ++  +     +       +   E   VLK+DN  V +T ++    N W     L++ERA+ELE+ ++ R    D+ G       L A  FL LEDFLD  R++  L + P+G +  +VTF NPV     +L+RQK++FSK++G+   R  +MN+DV  W R+        LR+    +  T       FS G S     P  +     +  V  LN    +D+      +    +     + +QE   P+    TQ++   A+  P++ +P       L   +F+ ++VLGRGHFGKVLL++++ +G+ +AIKALKK +I+AR+E+E+L  EKRI   +T + HPFLVNL  CFQ+ EHV FVMEY+ GGDLM+HI +D+F EPRA+FY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVL+YEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+S RDAEDVKKQPFFR+L ++ LLA+R+ P FVP L+   DVSNFD EFT E P L+P +D   LT ++Q
Sbjct:  126 SRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQAGQ--LENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPA------DHPKGRLLREELAAASSAAFS-TRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPWNPTPSMGGPGTPDSRPPFLSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWR----DQRG-------LCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRL--------LRRLIPNATGT-----GTFSPGAS-----PGSEARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSSLSSPIQESTAPELPSETQETPGPALCSPLRKSP-------LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQ 929

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN1 (protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405])

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 353/849 (41.58%), Postives = 499/849 (58.78%), Query Frame = 3

Query:  354 TSLKNLEHRLAIEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN--DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMK---PIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLG--------FSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQER--PQFQHSTQKSEY-AVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            + +  LE +LAIE+ V+ GAE ++Q +  G  KD       +++ ++SK KI  I  Q+ R     +  +EN     D   + +   +E+ I  L++   +E A+  G    LR + A    DR    +      ES QK+ L ++++++ + +LP+      D     L++          FS +RL     A   S L   + ++GTL +  +GC+DL ++ P N   +    G         S  +  ++  +     +       +   E   VLK+DN  V +T ++    N W     L++ERA+ELE+ ++ R    D+ G       L A  FL LEDFLD  R++  L + P+G +  +VTF NPV     +L+RQK++FSK++G+   R  +MN+DV  W R+        LR+    +  T       FS G S     P  +     +  V  LN    +D+      +    +     + +QE   P+    TQ++   A+  P++ +P       L   +F+ ++VLGRGHFGKVLL++++ +G+ +AIKALKK +I+AR+E+E+L  EKRI   +T + HPFLVNL  CFQ+ EHV FVMEY+ GGDLM+HI +D+F EPRA+FY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVL+YEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+S RDAEDVKKQPFFR+L ++ LLA+R+ P FVP L+   DVSNFD EFT E P L+P +D   LT ++Q
Sbjct:  132 SRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQAGQ--LENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPA------DHPKGRLLREELAAASSAAFS-TRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPWNPTPSMGGPGTPDSRPPFLSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWR----DQRG-------LCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRL--------LRRLIPNATGT-----GTFSPGAS-----PGSEARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSSLSSPIQESTAPELPSETQETPGPALCSPLRKSP-------LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQ 935

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN2 (protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406])

HSP 1 Score: 525.398 bits (1352), Expect = 1.433e-168
Identity = 353/891 (39.62%), Postives = 498/891 (55.89%), Query Frame = 3

Query:  315 DVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDD----SLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISP---------------PTMPAPNSD---------FSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQ--FQHSTQKS--EYAVMQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D    DP    S   LK L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + ++P N   S+I  ++    + S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN         ++    W                     K I+++S      W                   KF L L         VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP               P +  P SD                  PR S   +ID +   ++L  L I     P  + +       D  ++  + Q  ++  T +S  EY+ +Q ++    +R+ ++  +N  +FRC +VLGRGHFGKVLLA+YK+  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR +++  L+ K+VKP F+P +   EDVSNFD EFT E PILTP ++  +L+E +Q+
Sbjct:  123 DTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNT--------VVGQTSW---------------------KPISNQS------W-----------------DQKFTLELD-------RVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDES---SELRVLDI-----PGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELE---DRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQE 924

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN3 (protein kinase N3 [Source:HGNC Symbol;Acc:HGNC:17999])

HSP 1 Score: 469.929 bits (1208), Expect = 4.207e-148
Identity = 311/836 (37.20%), Postives = 461/836 (55.14%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQL------HKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNK--LKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVV--TDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            L+ L  +L +E+ V+ GAE +          + KL    +++  +S++K+  +  +I+        ++E           + +         L++R  +E A+  G      L   + T DR    +  +  +ES QK+ L + ++++ +++LP                P+  ++   + R                ++++GTL +  LGC+ L  + P     A   L  S +   +   A   + +       ++  E   VLK+DN+ V +T +  +++  W     + +ERA+ELE+ ++ R             W  L   +FL LEDFLD   ++  LSL P+G +F  VTF +PV   +  L+RQ+R+FSKR+GQ+ +R  +MN+ +  W R++ +         +TISPP             + T  R +  P    N +   T L        + P     ++  S E  T   +RP  +  T++       P  P    R   +L   +FRC++VLGRGHFGKVLL Q+K  GKYYAIKALKK E+L+R+E+E+L  EKRI + +  + HPFL++LL+CFQ++ H  FV E+  GGDLMM I  D+F EP+A FY  C+VLG+ FLH KKI+YRDLKLDNLLLD QG++K+ADFGLCKE +G GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVL+YEMLVGECPFPGD EEE+FD IVN +  YP  LS++    +++L+++ PE RLGA  +DAE++K QPFFR+ N+  LLA+ ++P FVP L    D+  F+ EFT   P LTP    +LLT   Q
Sbjct:  107 LEALRRQLHVELKVKQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKIS--------SLEASGSPEPGPELLAE--------ELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLLEQLPP-------------AHPLRSRVT-RELRAAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSPAAA--LASSPSEGWLRTKAKHQRGR------GELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVIPLERARELEIGVHWRD------------WRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVIERRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMN-LLPPCSSPSTISPPK--------GCPRTPTTLREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTSEE--TPRTKRPHMEPRTRRG------PSPPASPTRKPPRL--QDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFTGLPPALTPPAPHSLLTARQQ 873

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkn-1 (Protein Kinase N (PKN) homolog [Source:UniProtKB/TrEMBL;Acc:G5EGE3])

HSP 1 Score: 457.218 bits (1175), Expect = 2.262e-142
Identity = 323/883 (36.58%), Postives = 463/883 (52.43%), Query Frame = 3

Query:  369 LEHRLAIEISVRNGAEKLLQ--LHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGI-----KATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLP----SNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLS----------SISGTLAIGCLGCKD-LNDSFPTNLL--LAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLD-GGRNKFPLSLYPEGTIFIDVTFSNPVFGNK--LKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISS-GN--ATVLRKYTTISP--------------------------PTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQK--PHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQ-----KRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFR--SLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            L+  L  E+ V+ G E+ L+    K K+  +++ L ++S+ KI  +  QI R              E  AV    K  +E+ I +L  R   E+ IM G    I     K   D     + +++Y  + +K  L + ++ K    LP        + G+ +   + KP       SQ R  + P +    N T+ S           ISG L +   GC   L++ F   +   + G   GF S   +      +   + P S+      E  CVL+IDN+ +  T+ R I D  W    ++ ++R++EL+++++      DRS        +  F+ + L + ++   +    + + P+G IF+   + NPV   K  L+RQ+RLF  ++  +  R     + V  ++R+I + GN  +     +T  +P                          PT    NS F   ++   PR S K               A+A      P      Q ++ E    + E P     T +S  +   P+                L    FR ISVLGRGHFGKV+L+Q+     YYA+K LKK +IL R+E+E+L  EKRIF+  + ++HPFLVNL  CFQ+ EHV F MEY+ GGDLM HI  D+F+E R  FYA C+VLG+DFLH   I+YRD+KLDNLLLD +GYVK+ADFGLCKENMG  D+TSTFCGTPEFLAPEVL +  YTR++DWWGLGVLI+EMLVGE PF GD+EEEIFDSI++ ++RYPR+LS+E+  IMRRL+R+ PE RLG   RDAED+K Q FFR  S  +D LL + ++P F P++ N EDVSNFD EFTQE+   + A     +TE+DQ+
Sbjct:  164 LQLELEKELKVKRGLEQFLRGAPDKSKVHGDSQSLLDDSRAKIAMLRMQIERLSQ-----------EAPAVEGEPKTKVELAIDDLIIRFHKEKLIMDGSRNMIRILRSKRKPDSKAVDEAMNSYVIASEKADLIKLALLKYASSLPLEHDHRKYLIGEINSGLIPKPP----SLSQDR--NSPSSEDGGNGTSTSRRCSFMPYSLQISGCLEVTINGCAGILSEVFERKIRKDVPGVP-GFISVYGMDASGKKKKSARGPNSS-----EEVFCVLRIDNRFIGATELRKIVDRNWDQKFDVDLDRSRELQIELFYHD---DRS--------MCGFAAVKLSNLIETSSKVGIIVPVEPQGNIFVQFKYMNPVVSRKPKLERQRRLFRVKESNDGAR---QKLGVFAFSRLIKNRGNEPSEKFAAFTGFTPMPSSSSQHQPGTSSSGPSTSSSIASTPTPSTSNSLFDKSFN---PRKSAKKREAREAAAVAPMTAAVAAVNLNAPSTSNSMQPSTQERNLVVDEFP-----TDRSGPSQAPPVPAVRHIDFFASSDGAPLTVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDVFDEVRGCFYAACVVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLEFTQEKARFSAASSTRPITEADQR 1001

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkn-1 (Protein Kinase N (PKN) homolog [Source:UniProtKB/TrEMBL;Acc:G5EGE3])

HSP 1 Score: 456.447 bits (1173), Expect = 6.267e-141
Identity = 323/883 (36.58%), Postives = 463/883 (52.43%), Query Frame = 3

Query:  369 LEHRLAIEISVRNGAEKLLQ--LHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGI-----KATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLP----SNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLS----------SISGTLAIGCLGCKD-LNDSFPTNLL--LAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLD-GGRNKFPLSLYPEGTIFIDVTFSNPVFGNK--LKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISS-GN--ATVLRKYTTISP--------------------------PTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQK--PHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQ-----KRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFR--SLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            L+  L  E+ V+ G E+ L+    K K+  +++ L ++S+ KI  +  QI R              E  AV    K  +E+ I +L  R   E+ IM G    I     K   D     + +++Y  + +K  L + ++ K    LP        + G+ +   + KP       SQ R  + P +    N T+ S           ISG L +   GC   L++ F   +   + G   GF S   +      +   + P S+      E  CVL+IDN+ +  T+ R I D  W    ++ ++R++EL+++++      DRS        +  F+ + L + ++   +    + + P+G IF+   + NPV   K  L+RQ+RLF  ++  +  R     + V  ++R+I + GN  +     +T  +P                          PT    NS F   ++   PR S K               A+A      P      Q ++ E    + E P     T +S  +   P+                L    FR ISVLGRGHFGKV+L+Q+     YYA+K LKK +IL R+E+E+L  EKRIF+  + ++HPFLVNL  CFQ+ EHV F MEY+ GGDLM HI  D+F+E R  FYA C+VLG+DFLH   I+YRD+KLDNLLLD +GYVK+ADFGLCKENMG  D+TSTFCGTPEFLAPEVL +  YTR++DWWGLGVLI+EMLVGE PF GD+EEEIFDSI++ ++RYPR+LS+E+  IMRRL+R+ PE RLG   RDAED+K Q FFR  S  +D LL + ++P F P++ N EDVSNFD EFTQE+   + A     +TE+DQ+
Sbjct:  290 LQLELEKELKVKRGLEQFLRGAPDKSKVHGDSQSLLDDSRAKIAMLRMQIERLSQ-----------EAPAVEGEPKTKVELAIDDLIIRFHKEKLIMDGSRNMIRILRSKRKPDSKAVDEAMNSYVIASEKADLIKLALLKYASSLPLEHDHRKYLIGEINSGLIPKPPS----LSQDR--NSPSSEDGGNGTSTSRRCSFMPYSLQISGCLEVTINGCAGILSEVFERKIRKDVPGVP-GFISVYGMDASGKKKKSARGPNSS-----EEVFCVLRIDNRFIGATELRKIVDRNWDQKFDVDLDRSRELQIELFYHD---DRS--------MCGFAAVKLSNLIETSSKVGIIVPVEPQGNIFVQFKYMNPVVSRKPKLERQRRLFRVKESNDGAR---QKLGVFAFSRLIKNRGNEPSEKFAAFTGFTPMPSSSSQHQPGTSSSGPSTSSSIASTPTPSTSNSLFDKSFN---PRKSAKKREAREAAAVAPMTAAVAAVNLNAPSTSNSMQPSTQERNLVVDEFP-----TDRSGPSQAPPVPAVRHIDFFASSDGAPLTVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDVFDEVRGCFYAACVVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLEFTQEKARFSAASSTRPITEADQR 1127

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkc-1 (Protein kinase C-like 1B [Source:UniProtKB/Swiss-Prot;Acc:P34885])

HSP 1 Score: 291.582 bits (745), Expect = 1.407e-85
Identity = 148/312 (47.44%), Postives = 214/312 (68.59%), Query Frame = 3

Query: 1860 LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQ-TDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGA-SARDAED-VKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPA 2786
            L  ++F  + VLG+G FGKV+LA+ K   + YAIK LKK  I+  +++E    EKRI      +KHPFL  L S FQ+++ + FVMEY  GGDLM  IQ    F+E RA FYA  +   + FLH   ++YRDLKLDN+LLD +G+ ++ADFG+CKE +   + TSTFCGTP+++APE+L E +Y  SVDWW LGVL+YEM+ G+ PF  DNE+++F++I+N ++ YP  LS EA  I++  M +    RLG   ++  ED ++  PFFR +++D L +++VKP F PK+ ++ D +NFDS+FT+E P+LTP+
Sbjct:  286 LSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSL--AAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPS 595

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 291.582 bits (745), Expect = 5.857e-85
Identity = 150/321 (46.73%), Postives = 217/321 (67.60%), Query Frame = 3

Query: 1869 NNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQ-TDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARD---AEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            ++F  ++VLG+G FGKVLL + K+  + +AIK LKK  I+  +++E   +EKR+       K  FLV L SCFQ+ + + FVME+  GGDLM  IQ    F+EP AVFYA  I +G+ FLHSK I+YRDLKLDN++L+  G++K+ DFG+CKEN+     T TFCGTP+++APE+++ + Y +SVDWW  GVL++EML G+ PF G++E+E+F +I  H + YP+ LS EA  + + L+ + P  RLG +  D   + D+K+ PFFR +++  +  ++++P F PKL + +D SNFDSEFT E P LTP  DR  L   DQ
Sbjct:  346 SDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLAL--PEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKSADDTSNFDSEFTHEVPKLTPI-DRLFLMNLDQ 663

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 291.967 bits (746), Expect = 1.175e-84
Identity = 150/321 (46.73%), Postives = 217/321 (67.60%), Query Frame = 3

Query: 1869 NNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQ-TDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARD---AEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            ++F  ++VLG+G FGKVLL + K+  + +AIK LKK  I+  +++E   +EKR+       K  FLV L SCFQ+ + + FVME+  GGDLM  IQ    F+EP AVFYA  I +G+ FLHSK I+YRDLKLDN++L+  G++K+ DFG+CKEN+     T TFCGTP+++APE+++ + Y +SVDWW  GVL++EML G+ PF G++E+E+F +I  H + YP+ LS EA  + + L+ + P  RLG +  D   + D+K+ PFFR +++  +  ++++P F PKL + +D SNFDSEFT E P LTP  DR  L   DQ
Sbjct:  391 SDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLAL--PEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKSADDTSNFDSEFTHEVPKLTPI-DRLFLMNLDQ 708

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0088605)

HSP 1 Score: 439.499 bits (1129), Expect = 1.102e-140
Identity = 227/327 (69.42%), Postives = 268/327 (81.96%), Query Frame = 3

Query: 1839 QKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            Q      L  +NFR +SVLGRGHFGKV+L+Q +SN +YYAIKALKK +I+AR+E+E+L SEKRIF+     +HPFLVNL SCFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KI+YRDLKLDNLLLD +GYVK+ADFGLCKE MG GDRT TFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS+EA  +MRRL+R+ PE RLG+S RDAEDVKKQ FFRS+ +DDLL ++VKP FVP + + EDVSNFD EFT E+  LTP K+   LTE +Q
Sbjct:  251 QPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQ 577

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0339291)

HSP 1 Score: 447.203 bits (1149), Expect = 4.687e-137
Identity = 226/320 (70.62%), Postives = 267/320 (83.44%), Query Frame = 3

Query: 1860 LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            L  +NFR +SVLGRGHFGKV+L+Q +SN +YYAIKALKK +I+AR+E+E+L SEKRIF+     +HPFLVNL SCFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KI+YRDLKLDNLLLD +GYVK+ADFGLCKE MG GDRT TFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS+EA  +MRRL+R+ PE RLG+S RDAEDVKKQ FFRS+ +DDLL ++VKP FVP + + EDVSNFD EFT E+  LTP K+   LTE +Q
Sbjct:  835 LSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQ 1154

HSP 2 Score: 124.79 bits (312), Expect = 2.050e-28
Identity = 118/431 (27.38%), Postives = 201/431 (46.64%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQ-LHKG---KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMN------------------KCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN---DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNS----------QIFGDDSLSDLMKPIE-EQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHD-VQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRII 1523
            L +LE +L IE+ V+ GAE ++Q L  G   KL  E  ++  +SK KI+F+  +I + K   + A     D + A R M                   +  LE  I  L++R  IE A++ G    +R ++  N   D+   ++      ES +K+ L + S+    Q+LP++S          QI     LS    P+    ++  Q+ ++        S+L   +S++G L +  LGC+DL +  P        D   S      F   + S++     +  D   IE   V+K+DN  V +T ++  S   W     + ++R++ELE+ +Y R             W  L A   L LE+F+D  R+   L L P+G +F +V F NP+     KL+RQ+ +F++++ +NI R ++MN++V  W R++
Sbjct:  156 LASLEKQLQIEMKVKTGAENMIQSLGIGCDKKLLAEAHQMLADSKAKIEFLRLRIIKVKQNREQA-----DRLKASRQMIDEHGQTIGGNNSSQPQSLETTLEERIEELRHRLRIEAAVVDGAKNVIRTLQTANRAPDKKALQEAHGRLSESSRKLDLLRYSLDLRRQELPADSPAAQQLKTELQIV---QLSTSPAPVTYTSLQSGQAGILGGKPYQSVSSLGRCASVTGKLEVRLLGCQDLLEDVPGRSR-RDKDNNSSPGDLRSFVKGVTSRSSSKSYSVKDETSIEIMAVIKLDNITVGQTSWKQCSQQAWDQRFSIDLDRSRELEIGVYWRD------------WRSLCAVKVLRLEEFIDDVRHGMALQLEPQGLLFAEVKFLNPMISQKPKLRRQRMIFNRQQAKNISRAKQMNINVATWGRLL 565

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0088601)

HSP 1 Score: 447.203 bits (1149), Expect = 6.437e-137
Identity = 226/320 (70.62%), Postives = 267/320 (83.44%), Query Frame = 3

Query: 1860 LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            L  +NFR +SVLGRGHFGKV+L+Q +SN +YYAIKALKK +I+AR+E+E+L SEKRIF+     +HPFLVNL SCFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KI+YRDLKLDNLLLD +GYVK+ADFGLCKE MG GDRT TFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS+EA  +MRRL+R+ PE RLG+S RDAEDVKKQ FFRS+ +DDLL ++VKP FVP + + EDVSNFD EFT E+  LTP K+   LTE +Q
Sbjct:  858 LSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQ 1177

HSP 2 Score: 124.79 bits (312), Expect = 1.866e-28
Identity = 118/431 (27.38%), Postives = 201/431 (46.64%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQ-LHKG---KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMN------------------KCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN---DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNS----------QIFGDDSLSDLMKPIE-EQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHD-VQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRII 1523
            L +LE +L IE+ V+ GAE ++Q L  G   KL  E  ++  +SK KI+F+  +I + K   + A     D + A R M                   +  LE  I  L++R  IE A++ G    +R ++  N   D+   ++      ES +K+ L + S+    Q+LP++S          QI     LS    P+    ++  Q+ ++        S+L   +S++G L +  LGC+DL +  P        D   S      F   + S++     +  D   IE   V+K+DN  V +T ++  S   W     + ++R++ELE+ +Y R             W  L A   L LE+F+D  R+   L L P+G +F +V F NP+     KL+RQ+ +F++++ +NI R ++MN++V  W R++
Sbjct:  156 LASLEKQLQIEMKVKTGAENMIQSLGIGCDKKLLAEAHQMLADSKAKIEFLRLRIIKVKQNREQA-----DRLKASRQMIDEHGQTIGGNNSSQPQSLETTLEERIEELRHRLRIEAAVVDGAKNVIRTLQTANRAPDKKALQEAHGRLSESSRKLDLLRYSLDLRRQELPADSPAAQQLKTELQIV---QLSTSPAPVTYTSLQSGQAGILGGKPYQSVSSLGRCASVTGKLEVRLLGCQDLLEDVPGRSR-RDKDNNSSPGDLRSFVKGVTSRSSSKSYSVKDETSIEIMAVIKLDNITVGQTSWKQCSQQAWDQRFSIDLDRSRELEIGVYWRD------------WRSLCAVKVLRLEEFIDDVRHGMALQLEPQGLLFAEVKFLNPMISQKPKLRRQRMIFNRQQAKNISRAKQMNINVATWGRLL 565

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0088603)

HSP 1 Score: 447.588 bits (1150), Expect = 7.021e-137
Identity = 226/320 (70.62%), Postives = 267/320 (83.44%), Query Frame = 3

Query: 1860 LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            L  +NFR +SVLGRGHFGKV+L+Q +SN +YYAIKALKK +I+AR+E+E+L SEKRIF+     +HPFLVNL SCFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KI+YRDLKLDNLLLD +GYVK+ADFGLCKE MG GDRT TFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS+EA  +MRRL+R+ PE RLG+S RDAEDVKKQ FFRS+ +DDLL ++VKP FVP + + EDVSNFD EFT E+  LTP K+   LTE +Q
Sbjct:  873 LSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQ 1192

HSP 2 Score: 125.176 bits (313), Expect = 1.746e-28
Identity = 118/431 (27.38%), Postives = 201/431 (46.64%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQ-LHKG---KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMN------------------KCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN---DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNS----------QIFGDDSLSDLMKPIE-EQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHD-VQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRII 1523
            L +LE +L IE+ V+ GAE ++Q L  G   KL  E  ++  +SK KI+F+  +I + K   + A     D + A R M                   +  LE  I  L++R  IE A++ G    +R ++  N   D+   ++      ES +K+ L + S+    Q+LP++S          QI     LS    P+    ++  Q+ ++        S+L   +S++G L +  LGC+DL +  P        D   S      F   + S++     +  D   IE   V+K+DN  V +T ++  S   W     + ++R++ELE+ +Y R             W  L A   L LE+F+D  R+   L L P+G +F +V F NP+     KL+RQ+ +F++++ +NI R ++MN++V  W R++
Sbjct:  171 LASLEKQLQIEMKVKTGAENMIQSLGIGCDKKLLAEAHQMLADSKAKIEFLRLRIIKVKQNREQA-----DRLKASRQMIDEHGQTIGGNNSSQPQSLETTLEERIEELRHRLRIEAAVVDGAKNVIRTLQTANRAPDKKALQEAHGRLSESSRKLDLLRYSLDLRRQELPADSPAAQQLKTELQIV---QLSTSPAPVTYTSLQSGQAGILGGKPYQSVSSLGRCASVTGKLEVRLLGCQDLLEDVPGRSR-RDKDNNSSPGDLRSFVKGVTSRSSSKSYSVKDETSIEIMAVIKLDNITVGQTSWKQCSQQAWDQRFSIDLDRSRELEIGVYWRD------------WRSLCAVKVLRLEEFIDDVRHGMALQLEPQGLLFAEVKFLNPMISQKPKLRRQRMIFNRQQAKNISRAKQMNINVATWGRLL 580

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0308206)

HSP 1 Score: 448.743 bits (1153), Expect = 9.236e-137
Identity = 226/320 (70.62%), Postives = 267/320 (83.44%), Query Frame = 3

Query: 1860 LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            L  +NFR +SVLGRGHFGKV+L+Q +SN +YYAIKALKK +I+AR+E+E+L SEKRIF+     +HPFLVNL SCFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KI+YRDLKLDNLLLD +GYVK+ADFGLCKE MG GDRT TFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS+EA  +MRRL+R+ PE RLG+S RDAEDVKKQ FFRS+ +DDLL ++VKP FVP + + EDVSNFD EFT E+  LTP K+   LTE +Q
Sbjct:  928 LSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQ 1247

HSP 2 Score: 125.176 bits (313), Expect = 1.648e-28
Identity = 118/431 (27.38%), Postives = 201/431 (46.64%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQ-LHKG---KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMN------------------KCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN---DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNS----------QIFGDDSLSDLMKPIE-EQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHD-VQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRII 1523
            L +LE +L IE+ V+ GAE ++Q L  G   KL  E  ++  +SK KI+F+  +I + K   + A     D + A R M                   +  LE  I  L++R  IE A++ G    +R ++  N   D+   ++      ES +K+ L + S+    Q+LP++S          QI     LS    P+    ++  Q+ ++        S+L   +S++G L +  LGC+DL +  P        D   S      F   + S++     +  D   IE   V+K+DN  V +T ++  S   W     + ++R++ELE+ +Y R             W  L A   L LE+F+D  R+   L L P+G +F +V F NP+     KL+RQ+ +F++++ +NI R ++MN++V  W R++
Sbjct:  156 LASLEKQLQIEMKVKTGAENMIQSLGIGCDKKLLAEAHQMLADSKAKIEFLRLRIIKVKQNREQA-----DRLKASRQMIDEHGQTIGGNNSSQPQSLETTLEERIEELRHRLRIEAAVVDGAKNVIRTLQTANRAPDKKALQEAHGRLSESSRKLDLLRYSLDLRRQELPADSPAAQQLKTELQIV---QLSTSPAPVTYTSLQSGQAGILGGKPYQSVSSLGRCASVTGKLEVRLLGCQDLLEDVPGRSR-RDKDNNSSPGDLRSFVKGVTSRSSSKSYSVKDETSIEIMAVIKLDNITVGQTSWKQCSQQAWDQRFSIDLDRSRELEIGVYWRD------------WRSLCAVKVLRLEEFIDDVRHGMALQLEPQGLLFAEVKFLNPMISQKPKLRRQRMIFNRQQAKNISRAKQMNINVATWGRLL 565

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: PKN2 (zgc:153916 [Source:NCBI gene;Acc:567134])

HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0
Identity = 362/876 (41.32%), Postives = 522/876 (59.59%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNK--CDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYT--------TISPPTMPAPNSDFSAGYSMTCPRPSKKPDID--------HNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAV-MQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            PD  KSET +    +RLA       IE+ V+ GAE ++Q++        KL    +++ ++SK KI+FI  QI +    ++   EN+D     V T       L++ I  L++   IE A+  G      L G     ++    +  +   ES QK+ L + S+++ + +LP N    G   + +L           QS + +   +N+ S +   ++++GTL +  +GC+DL ++ P      ++ L G     + +S +   N  +S + R  S   D+  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     +V   ++         +S  T P  + D    +S+       K D D         N +  ++   A  D      E +   A+ + L N   +P +    +  +  + +  I+   + R  +++ ++  +F+C++VLGRGHFGKVLLA YK+ G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F E R+VFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG  DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYP++LS EA  IMRRL+RR PE RLGA  RDAE+VK+ PFFR +++  LLAK+++P FVP + + EDVSNFD EFT E PILTP ++  +LT  +Q
Sbjct:  120 PDTPKSETRMSTNSNRLAALKKQADIELKVKQGAENMIQMYSNGSSKDRKLLAAAQQMLQDSKTKIEFIRMQILKASQTSEINYENND-----VTTSKPIISPLDLRIEELRHHYRIESAVADGAKNVMKLLGTGKVTEKKAHSEAQARLNESSQKLDLLKFSLEQRLSELPKNHPK-GTLIMEELAMVASPPNSPRQSIMST---SNQYSTVAKPAALTGTLDVRLMGCQDLLENVPGRSKTASVSLPGWSPSEARSSFMSRGNKNKSGSSRTLSKSDDLSNEISAVLKLDNTVVGQTHWKPVSNQSWDQKFTLELDRSRELEIAVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPSVNTSFSPQAADLGSAMSHETAPMGHPD---AHSLPSDPTVTKLDFDKAVTPPSKRNSIEVEIEETAPPDKISDGKEVQDALATFDFLNNTVAKPDYDSLVEHEQPGLELTEIQRKTEIREEEEVQFSLSDFKCVAVLGRGHFGKVLLADYKTTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSETRSVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFKDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPKYLSTEAISIMRRLLRRNPERRLGAGERDAEEVKRHPFFRDMDWPGLLAKKIRPPFVPTITSREDVSNFDDEFTSEAPILTPPREPRILTLGEQ 971

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: PKN2 (zgc:153916 [Source:NCBI gene;Acc:567134])

HSP 1 Score: 591.652 bits (1524), Expect = 0.000e+0
Identity = 362/876 (41.32%), Postives = 522/876 (59.59%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNK--CDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYT--------TISPPTMPAPNSDFSAGYSMTCPRPSKKPDID--------HNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAV-MQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            PD  KSET +    +RLA       IE+ V+ GAE ++Q++        KL    +++ ++SK KI+FI  QI +    ++   EN+D     V T       L++ I  L++   IE A+  G      L G     ++    +  +   ES QK+ L + S+++ + +LP N    G   + +L           QS + +   +N+ S +   ++++GTL +  +GC+DL ++ P      ++ L G     + +S +   N  +S + R  S   D+  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     +V   ++         +S  T P  + D    +S+       K D D         N +  ++   A  D      E +   A+ + L N   +P +    +  +  + +  I+   + R  +++ ++  +F+C++VLGRGHFGKVLLA YK+ G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F E R+VFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG  DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYP++LS EA  IMRRL+RR PE RLGA  RDAE+VK+ PFFR +++  LLAK+++P FVP + + EDVSNFD EFT E PILTP ++  +LT  +Q
Sbjct:  100 PDTPKSETRMSTNSNRLAALKKQADIELKVKQGAENMIQMYSNGSSKDRKLLAAAQQMLQDSKTKIEFIRMQILKASQTSEINYENND-----VTTSKPIISPLDLRIEELRHHYRIESAVADGAKNVMKLLGTGKVTEKKAHSEAQARLNESSQKLDLLKFSLEQRLSELPKNHPK-GTLIMEELAMVASPPNSPRQSIMST---SNQYSTVAKPAALTGTLDVRLMGCQDLLENVPGRSKTASVSLPGWSPSEARSSFMSRGNKNKSGSSRTLSKSDDLSNEISAVLKLDNTVVGQTHWKPVSNQSWDQKFTLELDRSRELEIAVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPSVNTSFSPQAADLGSAMSHETAPMGHPD---AHSLPSDPTVTKLDFDKAVTPPSKRNSIEVEIEETAPPDKISDGKEVQDALATFDFLNNTVAKPDYDSLVEHEQPGLELTEIQRKTEIREEEEVQFSLSDFKCVAVLGRGHFGKVLLADYKTTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSETRSVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFKDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPKYLSTEAISIMRRLLRRNPERRLGAGERDAEEVKRHPFFRDMDWPGLLAKKIRPPFVPTITSREDVSNFDDEFTSEAPILTPPREPRILTLGEQ 951

[Close]

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNK--CDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYT--------TISPPTMPAPNSDFSAGYSMTCPRPSKKPDID--------HNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAV-MQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            PD  KSET +    +RLA       IE+ V+ GAE ++Q++        KL    +++ ++SK KI+FI  QI +    ++   EN+D     V T       L++ I  L++   IE A+  G      L G     ++    +  +   ES QK+ L + S+++ + +LP N    G   + +L           QS + +   +N+ S +   ++++GTL +  +GC+DL ++ P      ++ L G     + +S +   N  +S + R  S   D+  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     +V   ++         +S  T P  + D    +S+       K D D         N +  ++   A  D      E +   A+ + L N   +P +    +  +  + +  I+   + R  +++ ++  +F+C++VLGRGHFGKVLLA YK+ G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F E R+VFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG  DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYP++LS EA  IMRRL+RR PE RLGA  RDAE+VK+ PFFR +++  LLAK+++P FVP + + EDVSNFD EFT E PILTP ++  +LT  +Q
Sbjct:  113 PDTPKSETRMSTNSNRLAALKKQADIELKVKQGAENMIQMYSNGSSKDRKLLAAAQQMLQDSKTKIEFIRMQILKASQTSEINYENND-----VTTSKPIISPLDLRIEELRHHYRIESAVADGAKNVMKLLGTGKVTEKKAHSEAQARLNESSQKLDLLKFSLEQRLSELPKNHPK-GTLIMEELAMVASPPNSPRQSIMST---SNQYSTVAKPAALTGTLDVRLMGCQDLLENVPGRSKTASVSLPGWSPSEARSSFMSRGNKNKSGSSRTLSKSDDLSNEISAVLKLDNTVVGQTHWKPVSNQSWDQKFTLELDRSRELEIAVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPSVNTSFSPQAADLGSAMSHETAPMGHPD---AHSLPSDPTVTKLDFDKAVTPPSKRNSIEVEIEETAPPDKISDGKEVQDALATFDFLNNTVAKPDYDSLVEHEQPGLELTEIQRKTEIREEEEVQFSLSDFKCVAVLGRGHFGKVLLADYKTTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSETRSVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFKDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPKYLSTEAISIMRRLLRRNPERRLGAGERDAEEVKRHPFFRDMDWPGLLAKKIRPPFVPTITSREDVSNFDDEFTSEAPILTPPREPRILTLGEQ 964

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: pkn1a (protein kinase N1a [Source:ZFIN;Acc:ZDB-GENE-061207-17])

HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0
Identity = 358/850 (42.12%), Postives = 500/850 (58.82%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQLH-KGKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNK---CDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIA----NKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLA----GTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSA-GYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            +  LE +L IE+ V+ GAE ++ ++  G  KD+      +++ ++SK KI  I  QI +       A E++DD      T  K   C +E+ I  L++   +E A+  G      L G     D+    +      ES Q++ L + S+ + + +LP       D   + ++K  EE +  S     S   A    N+ S L+  S ++G L +  LGC  L +  P     + ++L     G    F  +   ++  +     K P  T  ++  +   VLK+DN  V +T ++++ +  W     +++ER++E+E+ +Y R   +           L A  FL LEDFLD  ++K  L L P+G +  +VTF NPV     +LKRQK +FSK++G+  +R  +MN+D+  + R++ +   TV     T SP        + S    S+    P K   +D  + VTD++         P  +   +  S  D+T     P   HS              + QK+T+  L   +FR I+VLGRGHFGKVLLA+YK +G  YAIKALKK +I+AR+E+E+L  EKRIF+ +  ++HPFLVNL +CFQ+ EHV FVMEY  GGDLMMHI  D+F EPRAVFY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+S +DAEDVKKQPFFR+++++ LL +++ P F+P +  +EDVSNFD EFT E P LTP ++  +L+  DQ
Sbjct:  127 IAALERQLNIELKVKQGAENMIPIYTNGSTKDKKMLQTAQQMLQDSKTKIDIIRMQIRKAVQ----AYEHNDD------TQGKPDPCGMELRIEELRHHYRVEHAVAEGAKNVLRLLGASKVQDKKAMSEAQCRLSESSQRLDLLRDSLDRRLAELPE------DHPKASVIK--EELVLASSPAFSSQHSAPYLHNQYSTLSKPSPLTGRLQVTLLGCMGLLEVVPGRSRGSQVVLPCYSPGEGRSFMRSGKGLYSRSGSVSGKTPLKT-DELSSDVSAVLKLDNTVVCQTAWKMVGEQGWDQTFIIELERSREMEIAVYWRDYRS-----------LCALKFLKLEDFLDNQKHKVQLELEPQGLLLAEVTFFNPVIERVPRLKRQKNVFSKQQGKAFLRARQMNVDIGTFVRLLRNAIPTV-NNTGTYSPNAHTLQTGEISVEKLSLDFDSPMK---VDIRREVTDIST--------PERQPSTEPLSAPDVTT----PIRTHSLS------------SKQKKTS--LSLQDFRLIAVLGRGHFGKVLLAEYKKSGSMYAIKALKKGDIVARDEVESLMCEKRIFEAVNGAQHPFLVNLFACFQTPEHVCFVMEYTAGGDLMMHIHADVFTEPRAVFYSACVVLGLQFLHDNKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSEKDAEDVKKQPFFRNMDWEALLLRKLPPPFIPSIGGKEDVSNFDEEFTTEAPTLTPPREPRVLSRKDQ 916

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: BX321890.2 (protein kinase N3 [Source:NCBI gene;Acc:323182])

HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0
Identity = 336/853 (39.39%), Postives = 503/853 (58.97%), Query Frame = 3

Query:  354 TSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLR-----GIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN--SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTS---TIIFQNALQSKTKRPGSTFHD-VQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKP---------DIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPI-KPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            + ++ L+ +L +E+ V+ GAE ++Q +        K+    +++ ++S+ KI+ +  QI +     +   E    E     T++   LE+ +  L++   IE A+  G        G++   DR    +  +  +ES QK+ L + S+++ + +LP +   +    + L+    P    I   + RL     ++  S+L   +S++G L +  +GC+DL +S P    ++       S S   ++  +  L +++    +T  D +  E   VLK+DNK V  T +R +S + W     +++ER++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +V F NPV     KL+RQKR+F K KG+N +R  +MNM+   W R++ S                +P  NS  +A   ++ P P  +P             +  V  LN      T+ P     +  ++ E L+     P   +ST+       +P  +PTPQ++   +++  +F CISVLGRGHFGKVLLA++K  GK YAIKALKK +++ R+E+++L  EKRIF+TI  S+HPFLVNL  CFQ+ +HV FVMEY+ GGDLM HI  +IF E +A FY+ C++LG++FLH  +IVYRDLKLDNLL+D  G+V++ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL + +YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR +S E+  ++++L+++  E RLGA  +DA +VKK  FF+ ++++ LLAKRVKP F+P +    DVSNFD EFT+ +P+LTP +    L+   Q+
Sbjct:  119 SHVRTLKKQLTMELKVKQGAENIIQTYTNSSVKDRKMLSTAQQMLQDSRTKIELLRMQIVKVTQAREGERETTQQEGRPSETISP--LELRVEELRHHLRIEAAVAEGAKNVVKQLGVRKVQDRRALAEAQARLQESSQKLDLLRLSLEQQLGELPQDHPKRAAIKEELTVGSSP---GIGLQRERL--RSSSSASSSLFKPASLTGRLEVRLMGCQDLLESVPGRCRVSNMSSAPGSPSDSKSLRMRTGLSTRSTNGKTTKTDELSSEISAVLKVDNKIVGRTHWRPLSKDAWNQSFSIELERSRELEIAVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFTEVRFINPVIERHPKLQRQKRIFPKEKGKNFLRAAQMNMNFATWGRLMMS---------------VLPPCNSTITA---LSPPLPGSEPLSPPSVSTPPSTGDSAVVKLNFSEERPTKPPRLHLAQNPSADESLSGT---PARVNSTEDRRVLQARPASQPTPQRKEGMQME--DFNCISVLGRGHFGKVLLAEFKRTGKLYAIKALKKGDVVTRDEVDSLMCEKRIFETINASRHPFLVNLYGCFQTPDHVCFVMEYSPGGDLMTHIHNNIFSERQARFYSACVLLGLEFLHQNRIVYRDLKLDNLLMDSDGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSNYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFMSPESVSVIQKLLQKNSEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPSIKTAADVSNFDEEFTRLKPVLTPPQTPFFLSAEQQE 929

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: mgc108147 (mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914997])

HSP 1 Score: 588.571 bits (1516), Expect = 0.000e+0
Identity = 368/865 (42.54%), Postives = 510/865 (58.96%), Query Frame = 3

Query:  333 PDDLKSETS-------LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQI-NRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN----SQIFGDDSL--SDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIE-----AKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIAD--TQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            PD  KS++        L  L+ +L IE+ V+ GAE ++Q +        KL    +++ ++SK KI+ I  QI   ++  N+ + +N    I          LE+ +  L++   IE A+  G      L G     DR    +  S + ES QK+ L + S+++ + +LP N    S I  + SL  S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     A   L   S S        ++   + GS+ + ++ E        +LK+DN  V +T ++ IS+  W     L+++R++ELE+ ++ R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV                 + S  YS     P+  P ++H+  +   + +A  D   +        + +S+ DL        +Q S +     V  P+   P       L   +F C +VLGRGHFGKVLLA+YKS  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR  +++ LLAK+VKP FVP +   EDVSNFD EFT E PILTP ++  +LTE +Q+
Sbjct:  110 PDTPKSDSGSSAFNGRLIALQKQLDIELKVKQGAENMIQTYSNGPSKDRKLLGTAQQMLQDSKTKIEVIRMQILQANQQTNEMSFDNAKPVISP--------LELRMEELRHHVRIEFAVTEGAKNVMKLLGSGKVTDRKALSEAHSRFNESSQKLDLLKYSLEQRLSELPKNHPKSSVIIEELSLVASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKAASATLPAWSPSEARSSFMSRTSKNKSGSSRNLLKTEEFSNEVCAMLKLDNTVVGQTNWKPISNQSWDQKFTLELDRSRELEISVFWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-----------------NHSGTYSPQVAVPAAVP-VNHHVFLYSESTVAKLDFDLEPEAPPAPPRSSSLGDL--------YQPSAEHKAPNVPVPVSLLPSFLIFTYL--QDFHCCAVLGRGHFGKVLLAEYKSTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRHTDWNALLAKKVKPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRILTEEEQE 916

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: mgc108147 (mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914997])

HSP 1 Score: 586.26 bits (1510), Expect = 0.000e+0
Identity = 367/865 (42.43%), Postives = 513/865 (59.31%), Query Frame = 3

Query:  333 PDDLKSETS-------LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQI-NRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN----SQIFGDDSL--SDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIE-----AKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIAD--TQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            PD  KS++        L  L+ +L IE+ V+ GAE ++Q +        KL    +++ ++SK KI+ I  QI   ++  N+ + +N      A   ++  +L ME   L++   IE A+  G      L G     DR    +  S + ES QK+ L + S+++ + +LP N    S I  + SL  S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     A   L   S S        ++   + GS+ + ++ E        +LK+DN  V +T ++ IS+  W     L+++R++ELE+ ++ R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV                 + S  YS     P+  P ++H+  +   + +A  D   +        + +S+ DL       +  +  + + Y     I    Q+R   +    +F C +VLGRGHFGKVLLA+YKS  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR  +++ LLAK+VKP FVP +   EDVSNFD EFT E PILTP ++  +LTE +Q+
Sbjct:  110 PDTPKSDSGSSAFNGRLIALQKQLDIELKVKQGAENMIQTYSNGPSKDRKLLGTAQQMLQDSKTKIEVIRMQILQANQQTNEMSFDNGKYLKTAKPVISPLELRME--ELRHHVRIEFAVTEGAKNVMKLLGSGKVTDRKALSEAHSRFNESSQKLDLLKYSLEQRLSELPKNHPKSSVIIEELSLVASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKAASATLPAWSPSEARSSFMSRTSKNKSGSSRNLLKTEEFSNEVCAMLKLDNTVVGQTNWKPISNQSWDQKFTLELDRSRELEISVFWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-----------------NHSGTYSPQVAVPAAVP-VNHHVFLYSESTVAKLDFDLEPEAPPAPPRSSSLGDLYQPSAEHKAPNVPELNTYLFTFRI----QQRF--QFSLQDFHCCAVLGRGHFGKVLLAEYKSTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRHTDWNALLAKKVKPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRILTEEEQE 926

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: mgc108147 (mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914997])

HSP 1 Score: 585.874 bits (1509), Expect = 0.000e+0
Identity = 361/848 (42.57%), Postives = 498/848 (58.73%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN----SQIFGDDSL--SDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIE-----AKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMED--LTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            L  L+ +L IE+ V+ GAE ++Q +        KL    +++ ++SK KI+ I  QI +  H +            AV   +  +L ME   L++   IE A+  G      L G     DR    +  S + ES QK+ L + S+++ + +LP N    S I  + SL  S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     A   L   S S        ++   + GS+ + ++ E        +LK+DN  V +T ++ IS+  W     L+++R++ELE+ ++ R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV   ++    P +  P +   A             D++         + ++ D  +P  E K  +    +  L   + + +FQ S Q                         +F C +VLGRGHFGKVLLA+YKS  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR  +++ LLAK+VKP FVP +   EDVSNFD EFT E PILTP ++  +LTE +Q+
Sbjct:  134 LIALQKQLDIELKVKQGAENMIQTYSNGPSKDRKLLGTAQQMLQDSKTKIEVIRMQILQANHSS-----------SAVDEQHPLELRME--ELRHHVRIEFAVTEGAKNVMKLLGSGKVTDRKALSEAHSRFNESSQKLDLLKYSLEQRLSELPKNHPKSSVIIEELSLVASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKAASATLPAWSPSEARSSFMSRTSKNKSGSSRNLLKTEEFSNEVCAMLKLDNTVVGQTNWKPISNQSWDQKFTLELDRSRELEISVFWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV--NHSGTYSPQVAVPAASTVAKLDF---------DLEPEAPPAPPRSSSLGDLYQPSAEHKAPNVPELNTYLFTFRIQQRFQFSLQ-------------------------DFHCCAVLGRGHFGKVLLAEYKSTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRHTDWNALLAKKVKPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRILTEEEQE 910

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: mgc108147 (mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914997])

HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0
Identity = 366/868 (42.17%), Postives = 511/868 (58.87%), Query Frame = 3

Query:  333 PDDLKSETS-------LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQI-NRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN----SQIFGDDSL--SDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIE-----AKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDID-HNKVVTDLNALAIA----DTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            PD  KS++        L  L+ +L IE+ V+ GAE ++Q +        KL    +++ ++SK KI+ I  QI   ++  N+ + +N    I          LE+ +  L++   IE A+  G      L G     DR    +  S + ES QK+ L + S+++ + +LP N    S I  + SL  S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     A   L   S S        ++   + GS+ + ++ E        +LK+DN  V +T ++ IS+  W     L+++R++ELE+ ++ R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV                 + S  YS     P+  P +D  N  ++ ++   +A    D +        + +S+ DL     +P  +H         +     T + +   +    +F C +VLGRGHFGKVLLA+YKS  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR  +++ LLAK+VKP FVP +   EDVSNFD EFT E PILTP ++  +LTE +Q+
Sbjct:  119 PDTPKSDSGSSAFNGRLIALQKQLDIELKVKQGAENMIQTYSNGPSKDRKLLGTAQQMLQDSKTKIEVIRMQILQANQQTNEMSFDNAKPVISP--------LELRMEELRHHVRIEFAVTEGAKNVMKLLGSGKVTDRKALSEAHSRFNESSQKLDLLKYSLEQRLSELPKNHPKSSVIIEELSLVASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKAASATLPAWSPSEARSSFMSRTSKNKSGSSRNLLKTEEFSNEVCAMLKLDNTVVGQTNWKPISNQSWDQKFTLELDRSRELEISVFWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-----------------NHSGTYSPQVAVPAAVPVVDPRNLELSPISESTVAKLDFDLEPEAPPAPPRSSSLGDLY----QPSAEHKAPNVPVPELNTYLFTFRIQQRFQFSLQDFHCCAVLGRGHFGKVLLAEYKSTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRHTDWNALLAKKVKPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRILTEEEQE 935

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: mgc108147 (mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914997])

HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0
Identity = 365/873 (41.81%), Postives = 504/873 (57.73%), Query Frame = 3

Query:  333 PDDLKSETS-------LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNK-------CDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN----SQIFGDDSL--SDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIE-----AKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHN----KVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            PD  KS++        L  L+ +L IE+ V+ GAE ++Q +        KL    +++ ++SK KI+ I  QI +             +EI  V T            LE+ +  L++   IE A+  G      L G     DR    +  S + ES QK+ L + S+++ + +LP N    S I  + SL  S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     A   L   S S        ++   + GS+ + ++ E        +LK+DN  V +T ++ IS+  W     L+++R++ELE+ ++ R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV   ++    P + A        + +     S    +D +           + ++ D  +P  E K  +     L   + + +FQ S Q                         +F C +VLGRGHFGKVLLA+YKS  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ +HV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR  +++ LLAK+VKP FVP +   EDVSNFD EFT E PILTP ++  +LTE +Q+
Sbjct:   95 PDTPKSDSGSSAFNGRLIALQKQLDIELKVKQGAENMIQTYSNGPSKDRKLLGTAQQMLQDSKTKIEVIRMQILQ--------ANQQTNEIGNVVTSYVPFTKPVISPLELRMEELRHHVRIEFAVTEGAKNVMKLLGSGKVTDRKALSEAHSRFNESSQKLDLLKYSLEQRLSELPKNHPKSSVIIEELSLVASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKAASATLPAWSPSEARSSFMSRTSKNKSGSSRNLLKTEEFSNEVCAMLKLDNTVVGQTNWKPISNQSWDQKFTLELDRSRELEISVFWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV--NHSGTYSPQVAARRVTKKVNHHVFLYSESTVAKLDFDLEPEAPPAPPRSSSLGDLYQPSAEHKAPNELNTYLFTFRIQQRFQFSLQ-------------------------DFHCCAVLGRGHFGKVLLAEYKSTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRHTDWNALLAKKVKPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRILTEEEQE 910

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn2 (protein kinase N2 [Source:MGI Symbol;Acc:MGI:109211])

HSP 1 Score: 590.112 bits (1520), Expect = 0.000e+0
Identity = 374/875 (42.74%), Postives = 517/875 (59.09%), Query Frame = 3

Query:  339 DLKSETS---LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPT-MPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHAS-----------MEDLTNLQERPQFQHSTQKSEYAVMQP--------IKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D +S TS   L  L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + +LP N   S +  ++ LS +  P    +   QS L +    N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN  V +T ++ IS+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP T +PA      A      P  S   D    K+  DL         +     +   +S            E + N++          KSEY +  P        +     KR  ++  ++  +FRC +VLGRGHFGKVLLA+YK   + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGA  +DAEDVKK PFFR  ++  L+ K+VKP FVP +   EDVSNFD EFT E PILTP ++  +L E +Q+
Sbjct:  128 DSRSSTSNNRLMALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPRNHPKSSVVIEE-LSLVASPT---LSPRQSMLSTQ---NQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSDNRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQTPVPATVPVVDARIPDLAPPAS---DSTVTKLDFDLEPEPPPAPPRASSLGETDESSELRVLDIPGQGSETVFNIENDRNNLRPKSKSEYELSIPDSGRSCWGVGELDDKRAQQRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQE 971

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn2 (protein kinase N2 [Source:MGI Symbol;Acc:MGI:109211])

HSP 1 Score: 585.104 bits (1507), Expect = 0.000e+0
Identity = 373/870 (42.87%), Postives = 513/870 (58.97%), Query Frame = 3

Query:  339 DLKSETS---LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPT-MPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHAS-----------MEDLTNLQERPQFQHSTQKSEYAVMQP--------IKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D +S TS   L  L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + +LP N   S +  ++ LS +  P    +   QS L +    N+ S L+  ++++GTL +  +GC+D+ ++ P       T +     S    +++  S+T +     +DV      VLK+DN  V +T ++ IS+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP T +PA      A      P  S   D    K+  DL         +     +   +S            E + N++          KSEY +  P        +     KR  ++  ++  +FRC +VLGRGHFGKVLLA+YK   + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGA  +DAEDVKK PFFR  ++  L+ K+VKP FVP +   EDVSNFD EFT E PILTP ++  +L E +Q+
Sbjct:  128 DSRSSTSNNRLMALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPRNHPKSSVVIEE-LSLVASPT---LSPRQSMLSTQ---NQYSTLSKPAALTGTLEVRLMGCQDILENVPGRS--KATSVALPGWSPSDNRSSFMSRTSK-----NDVC----AVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQTPVPATVPVVDARIPDLAPPAS---DSTVTKLDFDLEPEPPPAPPRASSLGETDESSELRVLDIPGQGSETVFNIENDRNNLRPKSKSEYELSIPDSGRSCWGVGELDDKRAQQRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQE 955

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn1 (protein kinase N1 [Source:MGI Symbol;Acc:MGI:108022])

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 359/867 (41.41%), Postives = 502/867 (57.90%), Query Frame = 3

Query:  354 TSLKNLEHRLAIEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCD-----LEMEIINLKNRCIIERAIMLGC------LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKP-IEEQIKFSQSRLVSHPI-ANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKT---KRPGSTFH----------------DVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLW----NRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEY-AVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            + +  LE +LAIE+ V+ GAE ++Q +  G  KD       +++ ++SK KI  I  Q+ R       A++  + E  A     + D     +E+ I  L++   +E A+  G       L G KA  DR    +      ES QK+ L ++S+++ + +LP+      D     L++  +      + S ++  P  A   S L+  + ++GTL +  +GCK+L ++ P           +S   ++      +S+T    RP    +                +   E   VLK+DN  V +T ++    N W     L++ERA+ELE+ ++ R    D+ G       L A  FL LEDFLD  R++  L + P+G +  +VTF NP+     +L+RQK++FSK++G+   R  +MN+DV  W     R+I S  AT      T SP   P      +   SM         D    K    L + + + +   H          E  T+    P+    TQ++    +  P++ +P       L   +F+ ++VLGRGHFGKVLL++++S+G+ +AIKALKK +I+AR+E+E+L  EKRI   +T + HPFLVNL  CFQ+ EHV FVMEY+ GGDLM+HI +D+F EPRAVFY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVL+YEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG++ RDAEDVKKQPFFRSL +D LLA+R+ P FVP L+   DVSNFD EFT E P L+P +D   LT ++Q
Sbjct:  126 SRVAGLEKQLAIELKVKQGAENMIQTYSNGSSKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQ----ALQAGELESQAAPDEAQGDPELGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSGAKAP-DRKAVSEAQEKLTESNQKLGLLRESLERRLGELPA------DHPKGRLLREELTAASSSAFSAILPGPFPATHYSTLSKPAPLTGTLEVRVVGCKNLPETIP-----------WSPPPSVGASGTPESRTPFLSRPARGLYSRSGSLSGRSSLRGEAENATEVSTVLKLDNTVVGQTAWKPCGPNAWDQSFTLELERARELELAVFWR----DQRG-------LCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPIIERIPRLQRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPSAVAT-----GTFSPNASPGAEIRHTGDISMEKLNLGADSDSSSQKSPPGLPSTSCSLSSPTH----------ESTTS----PELPSETQETPGPGLCSPLRKSP-------LTLEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQ 933

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn1 (protein kinase N1 [Source:MGI Symbol;Acc:MGI:108022])

HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0
Identity = 359/867 (41.41%), Postives = 502/867 (57.90%), Query Frame = 3

Query:  354 TSLKNLEHRLAIEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCD-----LEMEIINLKNRCIIERAIMLGC------LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKP-IEEQIKFSQSRLVSHPI-ANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKT---KRPGSTFH----------------DVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLW----NRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEY-AVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            + +  LE +LAIE+ V+ GAE ++Q +  G  KD       +++ ++SK KI  I  Q+ R       A++  + E  A     + D     +E+ I  L++   +E A+  G       L G KA  DR    +      ES QK+ L ++S+++ + +LP+      D     L++  +      + S ++  P  A   S L+  + ++GTL +  +GCK+L ++ P           +S   ++      +S+T    RP    +                +   E   VLK+DN  V +T ++    N W     L++ERA+ELE+ ++ R    D+ G       L A  FL LEDFLD  R++  L + P+G +  +VTF NP+     +L+RQK++FSK++G+   R  +MN+DV  W     R+I S  AT      T SP   P      +   SM         D    K    L + + + +   H          E  T+    P+    TQ++    +  P++ +P       L   +F+ ++VLGRGHFGKVLL++++S+G+ +AIKALKK +I+AR+E+E+L  EKRI   +T + HPFLVNL  CFQ+ EHV FVMEY+ GGDLM+HI +D+F EPRAVFY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVL+YEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG++ RDAEDVKKQPFFRSL +D LLA+R+ P FVP L+   DVSNFD EFT E P L+P +D   LT ++Q
Sbjct:  131 SRVAGLEKQLAIELKVKQGAENMIQTYSNGSSKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQ----ALQAGELESQAAPDEAQGDPELGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSGAKAP-DRKAVSEAQEKLTESNQKLGLLRESLERRLGELPA------DHPKGRLLREELTAASSSAFSAILPGPFPATHYSTLSKPAPLTGTLEVRVVGCKNLPETIP-----------WSPPPSVGASGTPESRTPFLSRPARGLYSRSGSLSGRSSLRGEAENATEVSTVLKLDNTVVGQTAWKPCGPNAWDQSFTLELERARELELAVFWR----DQRG-------LCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPIIERIPRLQRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPSAVAT-----GTFSPNASPGAEIRHTGDISMEKLNLGADSDSSSQKSPPGLPSTSCSLSSPTH----------ESTTS----PELPSETQETPGPGLCSPLRKSP-------LTLEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQ 938

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn2 (protein kinase N2 [Source:MGI Symbol;Acc:MGI:109211])

HSP 1 Score: 518.464 bits (1334), Expect = 3.240e-166
Identity = 353/874 (40.39%), Postives = 486/874 (55.61%), Query Frame = 3

Query:  339 DLKSETS---LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPT-MPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHAS-----------MEDLTNLQERPQFQHSTQKSEYAVMQP--------IKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D +S TS   L  L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + +LP N   S +  ++ LS +  P    +   QS L +    N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN         ++    W                     K I+++S      W                   KF L L         VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP T +PA      A      P  S   D    K+  DL         +     +   +S            E + N++          KSEY +  P        +     KR  ++  ++  +FRC +VLGRGHFGKVLLA+YK   + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGA  +DAEDVKK PFFR  ++  L+ K+VKP FVP +   EDVSNFD EFT E PILTP ++  +L E +Q+
Sbjct:  128 DSRSSTSNNRLMALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPRNHPKSSVVIEE-LSLVASPT---LSPRQSMLSTQ---NQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSDNRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNT--------VVGQTSW---------------------KPISNQS------W-----------------DQKFTLELD-------RVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQTPVPATVPVVDARIPDLAPPAS---DSTVTKLDFDLEPEPPPAPPRASSLGETDESSELRVLDIPGQGSETVFNIENDRNNLRPKSKSEYELSIPDSGRSCWGVGELDDKRAQQRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQE 923

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|Q16513|PKN2_HUMAN (Serine/threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1)

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 373/887 (42.05%), Postives = 528/887 (59.53%), Query Frame = 3

Query:  330 DPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDD----SLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISP---------------PTMPAPNSD---------FSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQ--FQHSTQKS--EYAVMQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            DP    S   LK L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + ++P N   S+I  ++    + S  + P +  I             N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN  V +T ++ IS+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP               P +  P SD                  PR S   +ID +   ++L  L I     P  + +       D  ++  + Q  ++  T +S  EY+ +Q ++    +R+ ++  +N  +FRC +VLGRGHFGKVLLA+YK+  + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR +++  L+ K+VKP F+P +   EDVSNFD EFT E PILTP ++  +L+E +Q+
Sbjct:  128 DPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSPRQSMIS----------TQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDES---SELRVLDI-----PGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELE---DRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQE 972

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|A7MBL8|PKN2_DANRE (Serine/threonine-protein kinase N2 OS=Danio rerio OX=7955 GN=pkn2 PE=2 SV=1)

HSP 1 Score: 591.652 bits (1524), Expect = 0.000e+0
Identity = 362/876 (41.32%), Postives = 522/876 (59.59%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNK--CDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYT--------TISPPTMPAPNSDFSAGYSMTCPRPSKKPDID--------HNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAV-MQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            PD  KSET +    +RLA       IE+ V+ GAE ++Q++        KL    +++ ++SK KI+FI  QI +    ++   EN+D     V T       L++ I  L++   IE A+  G      L G     ++    +  +   ES QK+ L + S+++ + +LP N    G   + +L           QS + +   +N+ S +   ++++GTL +  +GC+DL ++ P      ++ L G     + +S +   N  +S + R  S   D+  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     +V   ++         +S  T P  + D    +S+       K D D         N +  ++   A  D      E +   A+ + L N   +P +    +  +  + +  I+   + R  +++ ++  +F+C++VLGRGHFGKVLLA YK+ G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F E R+VFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG  DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYP++LS EA  IMRRL+RR PE RLGA  RDAE+VK+ PFFR +++  LLAK+++P FVP + + EDVSNFD EFT E PILTP ++  +LT  +Q
Sbjct:  113 PDTPKSETRMSTNSNRLAALKKQADIELKVKQGAEDMIQMYSNGSSKDRKLLAAAQQMLQDSKTKIEFIRMQILKASQTSEINYENND-----VTTSKPIISPLDLRIEELRHHYRIESAVADGAKNVMKLLGTGKVTEKKAHSEAQARLNESSQKLDLLKFSLEQRLSELPKNHPK-GTLIMEELAMVASPPNSPRQSIMST---SNQYSTVAKPAALTGTLDVRLMGCQDLLENVPGRSKTASVSLPGWSPSEARSSFMSRGNKNKSGSSRTLSKSDDLSNEISAVLKLDNTVVGQTHWKPVSNQSWDQKFTLELDRSRELEIAVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPSVNTSFSPQAADLGSAMSHETAPMGHPD---AHSLPSDPTVTKLDFDKAVTPPSKRNSIEVEIEETAPPDKISDGKEVQDALATFDFLNNTVAKPDYDSLVEHEQPGLELTEIQRKTEIREEEEVQFSLSDFKCVAVLGRGHFGKVLLADYKTTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSETRSVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFKDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPKYLSTEAISIMRRLLRRNPERRLGAGERDAEEVKRHPFFRDMDWPGLLAKKIRPPFVPTITSREDVSNFDDEFTSEAPILTPPREPRILTLGEQ 964

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|Q8BWW9|PKN2_MOUSE (Serine/threonine-protein kinase N2 OS=Mus musculus OX=10090 GN=Pkn2 PE=1 SV=3)

HSP 1 Score: 590.112 bits (1520), Expect = 0.000e+0
Identity = 374/875 (42.74%), Postives = 517/875 (59.09%), Query Frame = 3

Query:  339 DLKSETS---LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPT-MPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHAS-----------MEDLTNLQERPQFQHSTQKSEYAVMQP--------IKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D +S TS   L  L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + +LP N   S +  ++ LS +  P    +   QS L +    N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN  V +T ++ IS+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP T +PA      A      P  S   D    K+  DL         +     +   +S            E + N++          KSEY +  P        +     KR  ++  ++  +FRC +VLGRGHFGKVLLA+YK   + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGA  +DAEDVKK PFFR  ++  L+ K+VKP FVP +   EDVSNFD EFT E PILTP ++  +L E +Q+
Sbjct:  128 DSRSSTSNNRLMALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPRNHPKSSVVIEE-LSLVASPT---LSPRQSMLSTQ---NQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSDNRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQTPVPATVPVVDARIPDLAPPAS---DSTVTKLDFDLEPEPPPAPPRASSLGETDESSELRVLDIPGQGSETVFNIENDRNNLRPKSKSEYELSIPDSGRSCWGVGELDDKRAQQRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQE 971

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|A1A4I4|PKN1_BOVIN (Serine/threonine-protein kinase N1 OS=Bos taurus OX=9913 GN=PKN1 PE=2 SV=1)

HSP 1 Score: 580.867 bits (1496), Expect = 0.000e+0
Identity = 355/853 (41.62%), Postives = 495/853 (58.03%), Query Frame = 3

Query:  354 TSLKNLEHRLAIEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN--DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKP--IEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKC--------VLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLW----NRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQER---PQFQHSTQKSEYAVM-QPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            + +  LE +LAIE+ V+ GAE ++Q +  G  KD       +++ ++SK KI  I  Q++R     +   +   DE      +   +L +E   L++   +E A+  G    LR + A    DR    +      ES QK+ L ++++++ + +LP+      D     L++            +RL     A   S L+  + ++GTL +  +GC+DL ++ P N   +    G   + T       +    R GS      ++A+         VLK+DN  V +T ++    N W     L++ERA+ELE+ ++ R    D+ G       L A  FL LEDFLD  R++  L + P+G +  +VTF NPV     +L+RQK++FSK++G+   R  +MN+DV  W     R+I +  AT      T SP   P P +  +   S                 V  LN     D+           +     + +Q     P+    TQ++    +  P++ +P       L   +F+ ++VLGRGHFGKVLL++++ +G+ +AIKALKK +I+AR+E+E+L  EKRI   +T + HPFLVNL  CFQ+ EHV FVMEY+ GGDLM+HI +D+F EPRAVFY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVL+YEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+S RDAEDVKKQPFFR+L +D LLA+R+ P FVP LA   DVSNFD EFT E P L+P +D   LT ++Q
Sbjct:  127 SRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLHRALQACQLESQAAPDEAQGSPDLGAVELRIE--ELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPA------DHPKGRLLREELAAASSAAFSARLAGPFPATHYSTLSKPAPLTGTLEVRVVGCRDLPETIPWNPSPSVGGPGTPDSRTPFLSRPARGLYSRTGSLSGRSSLKAEAENTNEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWR----DQRG-------LCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPNATAT-----GTFSPGASPGPEARSTGDIS-----------------VEKLNLGTETDSSPQKSPLGPPSSPSSLSSPIQATTTTPELPSETQETPGPTLCSPLRKSP-------LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTNAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWDALLARRLPPPFVPTLAGRTDVSNFDEEFTGEAPTLSPPRDARPLTATEQ 931

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|Q16512|PKN1_HUMAN (Serine/threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 353/849 (41.58%), Postives = 499/849 (58.78%), Query Frame = 3

Query:  354 TSLKNLEHRLAIEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC---LRGIKATN--DRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMK---PIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLG--------FSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQER--PQFQHSTQKSEY-AVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            + +  LE +LAIE+ V+ GAE ++Q +  G  KD       +++ ++SK KI  I  Q+ R     +  +EN     D   + +   +E+ I  L++   +E A+  G    LR + A    DR    +      ES QK+ L ++++++ + +LP+      D     L++          FS +RL     A   S L   + ++GTL +  +GC+DL ++ P N   +    G         S  +  ++  +     +       +   E   VLK+DN  V +T ++    N W     L++ERA+ELE+ ++ R    D+ G       L A  FL LEDFLD  R++  L + P+G +  +VTF NPV     +L+RQK++FSK++G+   R  +MN+DV  W R+        LR+    +  T       FS G S     P  +     +  V  LN    +D+      +    +     + +QE   P+    TQ++   A+  P++ +P       L   +F+ ++VLGRGHFGKVLL++++ +G+ +AIKALKK +I+AR+E+E+L  EKRI   +T + HPFLVNL  CFQ+ EHV FVMEY+ GGDLM+HI +D+F EPRA+FY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVL+YEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+S RDAEDVKKQPFFR+L ++ LLA+R+ P FVP L+   DVSNFD EFT E P L+P +D   LT ++Q
Sbjct:  126 SRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQAGQ--LENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPA------DHPKGRLLREELAAASSAAFS-TRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPWNPTPSMGGPGTPDSRPPFLSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWR----DQRG-------LCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRL--------LRRLIPNATGT-----GTFSPGAS-----PGSEARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSSLSSPIQESTAPELPSETQETPGPALCSPLRKSP-------LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQ 929

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A4Z2DPT2 (Serine/threonine-protein kinase N2 OS=Schistosoma japonicum OX=6182 GN=EWB00_010144 PE=4 SV=1)

HSP 1 Score: 615.535 bits (1586), Expect = 0.000e+0
Identity = 423/1077 (39.28%), Postives = 593/1077 (55.06%), Query Frame = 3

Query:  117 RTKLNVCYKNKAGIQKM----------LVPENNSSAV---LVDEKRSLNM------------IKSLNIEITDYXXXXXXXXXXXXXXXQFEDVQIQDPDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHKG---KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEI--------DAVRTMNKCD--------------LEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRD------LLSNYRESYQKIFLYQKSIQKAIQKLPSN------SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLS--------SISGTLAIGCLGCKDLNDSFPTNLL---LAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKI-ITDRSGSSCNG-----------------WVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNK---LKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSM----------------TCPRPSKK---PDIDHNKVVTDLNALAIADTQKPHYE----------------KKKQHASMEDLTNLQERPQFQHST--------QKSEYAVM--------------------------------QPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            R+ L   YK KAG+QK+          +VP +N   +   LV  K S  +            IK +N ++ D    I DL+  +L+LK ++          KS     +++ RLA       IE+ VR+GAE+L+Q +K     + +E ++ YE +  KI FI NQ+ R K  N+   + D   +        D  +T    +               + +++ L +R  +ERA+ +G  + + A  D     D       L   RES  +++L+Q+SI+  ++K P        S I GD  ++ L+               S P  N  S   N S        +I+G+L + CLGC+D+ D FP  L+   L+GT    S+T      + L S+T    S  H   +  +C L ID+K V+++ +R  +  CW   T   I+R KELEVQ+Y +++ +   S +S +G                 WVL A S++ LE+ L G      L + P G +F+ + FS+P+       L RQKRLFSKRKG NI R  E++M++PLW R++ SG  + + +       T+       S+G  +                  P P +     D+D    ++    +AI  +  P Y+                K      + D  N +E   FQ +T        + ++Y  M                                + +   P  + T  L   + R ++VLGRGHFGKVLLAQY  + KYYAIKALKKAEI+ RNE++TL +EKRIF+ IT+++HPFL+NL +CFQ+ EHV+FVMEYA+GGDLM+HIQ D+F+EPRAVFYAGC+VLGI+FLHS+KIVYRDLKLDNLLLD +G+VKMADFGLCKE MG  DRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVLI+EMLVGECPFPG++EEEIF+SIVN E+RYPRHLSMEAT+IMRRL+RR    RLG+SA+DAE++K+QPFFR L+F  LLA+++KP FVP +++ EDVSNFD EFT+E+ +LTPAKDR  L ++DQ
Sbjct:   52 RSDLQKLYKMKAGVQKLQDAVGKSFSAVVPSSNDYMIGGNLVGTKESYTLDRKSSRTTTSAVIKGINSDVQDLAEDIGDLETSLLLLKHYQPSLDHQNAVTKSADGGYSIDQRLAELQKALDIELQVRSGAERLIQTYKSGPRHILEEAKKQYENANNKIGFIRNQMIRVKQMNEGFYQPDAASLGTGSENISDTSKTNGSINSNSSVSGNQEGFLIWKDKVMELAHRLRVERALFVGSKKAVNAVLDNQAHVDKYRKLQALQEARESLHRLYLFQESIKSLLRKPPPTQFPEMVSSIVGDPEMNVLL---------------SSPWCNTTSYHANSSLLIPNPPTAITGSLEVRCLGCQDIIDHFPAELVNNELSGT----SATRINSIPSILTSRT----SDSHCADV--RCSLLIDHKRVWDSPWRQPNQQCWDSKTTFNIDRGKELEVQVYWKRMHLPANSSTSPSGLTSSKSGSSDDSGSGLEWVLAAISYVRLEELLGGESRSVMLPMLPTGRVFLVLKFSDPLLSKPRCGLHRQKRLFSKRKGHNIPRINELDMNIPLWTRMLKSGQLSKMNRSVAGGSWTLSHSGEYGSSGSVVLHGIEGRFHQLNTSLSGSPAPVQSHLVDDVDDYSPISHRPPVAINSSSSPDYDVAPVIIEYDENSKFSHKPDTSFRVSDYANPEEITSFQMTTLDQNDPDSRTADYVNMDVQRSYSGPVVLSAENEKRDIPTAESPRPLTSETVNELPSDKPTTILSMIDIRPVAVLGRGHFGKVLLAQYHRDKKYYAIKALKKAEIIFRNEVDTLLAEKRIFKIITDAQHPFLINLFACFQTKEHVMFVMEYAQGGDLMLHIQQDVFKEPRAVFYAGCVVLGIEFLHSQKIVYRDLKLDNLLLDSEGFVKMADFGLCKEGMGPDDRTSTFCGTPEFLAPEVLTDSSYTRAVDWWGLGVLIFEMLVGECPFPGESEEEIFESIVNREVRYPRHLSMEATIIMRRLLRRNAAQRLGSSAQDAEEIKRQPFFRKLDFTALLARKIKPPFVPVVSDPEDVSNFDEEFTREKAVLTPAKDRPPLLDADQ 1103

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A2K5H996 (Protein kinase N2 OS=Colobus angolensis palliatus OX=336983 GN=PKN2 PE=4 SV=1)

HSP 1 Score: 602.823 bits (1553), Expect = 0.000e+0
Identity = 380/888 (42.79%), Postives = 531/888 (59.80%), Query Frame = 3

Query:  315 DVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISP---------------PTMPAPNSD---------FSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQ--FQHSTQKS--EYAVMQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D    DP    S   LK L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + +LP N   S I  ++ LS +  P    +   QS + +    N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN  V +T ++ IS+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP               P + AP SD                  PR S   +ID +      + L + DT  P  + +       D  ++  + Q  ++  T +S  EY+ MQ ++    KR+ ++  +N  +FRC +VLGRGHFGKVLLA+YK   + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR +++  L+ K+VKP F+P +   EDVSNFD EFT E PILTP ++  +L+E +Q+
Sbjct:  123 DTPNSDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPKNHPKSSIIIEE-LSLVASPT---LSPRQSMISTQ---NQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQAPVPTTVPVVDVRIPELAAPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDES------SELRVLDT--PGQDSETVFDIENDRNSILPKSQSEYKPDTPQSGLEYSGMQELE---DKRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQE 971

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A2K5H957 (Protein kinase N2 OS=Colobus angolensis palliatus OX=336983 GN=PKN2 PE=4 SV=1)

HSP 1 Score: 602.823 bits (1553), Expect = 0.000e+0
Identity = 380/888 (42.79%), Postives = 531/888 (59.80%), Query Frame = 3

Query:  315 DVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISP---------------PTMPAPNSD---------FSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQ--FQHSTQKS--EYAVMQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D    DP    S   LK L+ +L IE+ V+ GAE ++Q++        KL    ++L ++SK KI+ I  QI +    N+ A +N    I          LE+ +  L++   IE A+  G      L G     DR    +  + + ES QK+ L + S+++ + +LP N   S I  ++ LS +  P    +   QS + +    N+ S L+  ++++GTL +  +GC+D+ ++ P     T++ L G     + +S +   +  +S + R      D+  +   VLK+DN  V +T ++ IS+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     T SP               P + AP SD                  PR S   +ID +      + L + DT  P  + +       D  ++  + Q  ++  T +S  EY+ MQ ++    KR+ ++  +N  +FRC +VLGRGHFGKVLLA+YK   + +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ +LH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGAS +DAEDVKK PFFR +++  L+ K+VKP F+P +   EDVSNFD EFT E PILTP ++  +L+E +Q+
Sbjct:  123 DTPNSDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRMQILQAVQTNELAFDNAKPVISP--------LELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPKNHPKSSIIIEE-LSLVASPT---LSPRQSMISTQ---NQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV-NHSGTFSPQAPVPTTVPVVDVRIPELAAPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDES------SELRVLDT--PGQDSETVFDIENDRNSILPKSQSEYKPDTPQSGLEYSGMQELE---DKRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQE 971

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A4W6FI09 (Uncharacterized protein OS=Lates calcarifer OX=8187 GN=pkn2 PE=4 SV=1)

HSP 1 Score: 602.053 bits (1551), Expect = 0.000e+0
Identity = 360/865 (41.62%), Postives = 501/865 (57.92%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDL-GFSSTST----IIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISP----------PTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            PD   SE  +     RLA       IE+ V+ GAE ++Q++        KL    +++ ++SK KI+FI  QI +    N+ + EN+D  I          L++ +  L +   IE A+  G      L G     ++    +  + + ES QK+ L + S+++ + +LP N       S+ + +  +   +   +S ++S    N+ S +T  ++++GTL +  +GC+DL ++ P     A   L G+S + T    I   N  +  + R  +   ++  E   VLK+DN  V +T +R +S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+G +F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     TV     + SP          P  P P+SD           P+  P   H     D+    + D      E + Q      +  ++E  QF  S Q                         +F+C++VLGRGHFGKVLLA+YKS G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F EPRAVFYA C+VLG+ FLH  KI + DL  DNLLLD +GYVK+ADFGLCKE MG  DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR+PE RLGA  RDAE+VKK  FFR ++++ LLAK+VKP FVP +    DVSNFD EFT E PILTP ++  +L+  +Q
Sbjct:  113 PDTPNSEARMCTSSSRLAALKRQNDIELKVKQGAENMIQMYSNGPSKDRKLLATAQQMLQDSKTKIEFIRMQILKASQANELSFENNDPIISP--------LDLRVEELCHHARIESAVAEGAKNVMKLLGSGKVTEKRAHSEAQARFNESSQKLDLLRYSLEQRLNELPKNHP--RSSSIIEELSLLSSPVLSPRSSIIS--TQNQYSTVTKPAALTGTLDVRLMGCQDLLENVPGRSKAASVPLPGWSPSETRSSFISRANRNRGVSSRNLTKSEELSNEISAVLKLDNTVVGQTSWRPVSNQAWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGMLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV--STNSFSPQAAETGPSSLPGSPTPSSDPLVTKLDFDKEPTPGPK--HYPTPDDIREPLVQDKMPDKEEVQVQVFQESQVVPIREEEQFHFSLQ-------------------------DFKCVAVLGRGHFGKVLLAEYKSTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTQEHVCFVMEYAAGGDLMMHIHADVFSEPRAVFYAACVVLGLQFLHDHKIKHHDL--DNLLLDTEGYVKIADFGLCKEGMGFRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRSPERRLGAGERDAEEVKKHLFFRHMDWNGLLAKKVKPPFVPTIQGANDVSNFDDEFTSEAPILTPPREPRMLSSEEQ 922

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A3S2LTY6 (Uncharacterized protein OS=Oryzias javanicus OX=123683 GN=OJAV_G00167490 PE=4 SV=1)

HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0
Identity = 376/886 (42.44%), Postives = 524/886 (59.14%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNK---CDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDL-GFSSTST----IIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNK--LKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISP----------PTMPAPNSDFSAGY----SMTCPRPSKKP-------------DIDHNKVVTDLNALAIADTQKPHYEKKKQHASME-DLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            PD   SE  +     RLA       IE+ V+ GAE ++Q++  G  KD       +++ ++SK KI+FI  QI +       A +  +   D    M+K     L++ +  L +   IE A+  G      L G     ++    +  + + ES QK+ L + S++  + +LP +       S+ + +  +       +S ++S    N+ S +T  ++++GTL +  +GC+DL ++ P  L  A   L G+S + T    I   N  +S + R  +   ++  E   VLK+DN  V +T +R  S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+G +F +VTF NPV   +  L+RQK++FSK++G+  +R  +MN+++  W R +     TV     + SP          P  PAP SD         +   PRP   P              +DH   V   NAL+  D     +  K+    M  DL ++ ++ + +H   + E+ V +     P+ R  ++    +FRC++VLGRGHFGKVLLA+YKS G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRAVFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+ DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR+PE RLGA  +DAE+VKK PFFR +++  LLAK+VKP FVP + +  DVSNFD EFT E P+LTP +D  +L+  +Q
Sbjct:  186 PDTPTSEARMTTSSGRLAALKRQNDIELKVKQGAENMIQMYSNGSSKDRKLLATAQQMLQDSKTKIEFIRMQILK-------ASQETELSFDTSEVMDKPIISPLDLRVEELCHHARIESAVAEGAKNVMKLLGSGKVTEKKAHSEAQARFNESSQKLDLLRHSLELRLNELPKSDP--RSHSIIEELSLLSSPALSPRSSIIS--TQNQYSTVTKPAALTGTLDVRLMGCQDLLENIPGRLKTASVPLPGWSPSETRSSFISRANRNRSVSSRNLAKSEELSNEISAVLKLDNTVVGQTSWRPASNQAWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGMLFAEVTFFNPVIERRPRLQRQKKIFSKQQGKTFLRAPQMNINIATWGRQVRRAIPTV--STNSFSPQAAETGHGSLPGSPAPCSDPLVTKLDFDTEPTPRPKHYPAPEVAVEPPALLQPLDHKDEVQ--NALSSFD-----FLTKRNSIVMNPDLESILDQ-KLRHP--ELEFTVHKARDADPEIREDEQFSLQDFRCVAVLGRGHFGKVLLAEYKSTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTAEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYKDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRSPERRLGAGEKDAEEVKKHPFFRDMDWSGLLAKKVKPPFVPTIQDANDVSNFDEEFTSEAPVLTPPRDPRMLSSEEQ 1036

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: zgc:153916 (serine/threonine-protein kinase N2 [Source:NCBI gene;Acc:103027669])

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 375/914 (41.03%), Postives = 532/914 (58.21%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTM-NKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDL-GFSSTSTIIFQNALQSKTK--RPGSTFH-----DVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTM-------PAPNS------------------DFSAGYSMTCPRPS-------------KKPDI---------------DHNKVVT--DLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            PD   SET       RLA       IE+ V+ GAE ++Q++  G  KD       +++ ++SK KI+FI  QI +    N+   EN+D  + A +++ +  DL +E   L++   IE A+  G      L G     ++    +  + + ES QK+ L + S+++ + +LP N        +S+ +  +    +  +  ++S    N+ S +   ++++GTL +  +GC+DL ++ P     A   L G+S + T   +++  S+T   R GS+ +     ++  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R     RS        L A  FL LEDFLD  R+   L L P+G +F++VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     +V     + SPP         P P +                  DF  G +    R S             K PD                  N  VT  D ++L + D Q+P  E      S +++T  +E P+ Q S +                         +F+C++VLGRGHFGKVLLA+Y+S G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F EPRAVFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+ DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR P+ RLGA  RDAE+VKK PF R++++  LLAK+++P FVP +   EDVSNFD EFT E PILTP ++  +LT ++Q+
Sbjct:  115 PDTPSSETRTCTNSSRLAALKKQNDIELKVKQGAENMIQMYSNGSYKDRKLLAMAQQMLQDSKTKIEFIRMQILKASQTNEVTYENND--VPANKSIISPLDLRLE--ELRHHFRIESAVAEGAKNVMKLLGSGKVTEKKAHSEAQARFNESSQKLDLLKFSLEQRLSELPKNHP--KASVISEELAMVASPPQSPRQSIISS--QNQYSTVAKPAALTGTLEVRLMGCQDLLENVPGRSKAASVSLPGWSPSET---RSSFMSRTNKNRAGSSRNLSKADELSNEISAVLKLDNTVVGQTTWKPVSNQSWDQKFTLELDRSRELEISVYWRDY---RS--------LCAVKFLRLEDFLDNQRHGMCLYLEPQGKLFVEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPSV---NNSFSPPVAELGSALSPEPGAIGHPDSPPLSSDPTVTKLDFDKGATPPSNRHSNSVELEEELPTKDKVPDGREVQDALATFDFLNDSRNSAVTKPDYDSLVVDDVQQPDLE-----LSSQEITEKREEPEIQFSIR-------------------------DFKCVAVLGRGHFGKVLLAEYRSTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSEPRAVFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYQDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPDRRLGAGERDAEEVKKHPFLRNVDWGALLAKKIQPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRVLTANEQE 973

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: pkn2 (serine/threonine-protein kinase N2 [Source:NCBI gene;Acc:103040528])

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 363/880 (41.25%), Postives = 522/880 (59.32%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFG--NKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRII-------SSGNATVLRKYT-TISPPTMPAPNSD-FSAGYSMTCPR--PSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTN----LQERPQF----QHSTQKSEYAVMQPIKPTPQKRTTKK---------LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            PD   SE  L  L+ ++ IE+ V+ GAE ++Q++        KL    +++ ++S++KI+FI  QI +    ++ + +N+D  + A   ++  DL +E   L +   IE A+  G      + G     ++    +  + + ES QK+ L + S+++ + +LP +   S I  ++ LS +  P        ++ L+S    N  S +   ++++GTL +  +GC+DL +  P     T L L G     + +S +   +  ++ + R  S   D+  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++       S+ N T  +    T      P PN+   S+  ++T       + P   H  +V+    L   + + P  E+ +   S  D  N    L  +P+     QH  Q     ++   K T  +                  +F+C++VLGRGHFGKVLLA+Y S G+ +AIKALKK +I++R+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRA FYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG  DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  +MRRL+RR PE RLG   RDAE+VKK  FFR++++  LL K+VKP FVP + +  DVSNFD EFT E P+LTP +D+  L+  +Q+
Sbjct:  113 PDTPSSEGRLAALKKQIDIELKVKQGAENMIQMYSNGSSKDRKLLATAQQMLQDSRMKIEFIRMQILKASQSHELSFDNND--VIAKPIISPLDLRVE--ELCHHARIEHAVAEGAKNVMKILGSGKLTEKKTHSEAQARFNESSQKLDLLKYSLEQRLSELPKHHPKSSIIMEE-LSLMSSPALS----PRNSLIS--TQNPYSTIAKPAALTGTLDVRLMGCQDLLEDVPGRSKATTLTLPGWSPSDTRSSFMSRGSRSRTASIRNLSKTDDLSNEISAVLKLDNTVVGQTSWKPVSNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCALKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRTKLQRQKKIFSKQQGRTFLRAPQMNINIATWGRLVRRAIPSVSNSNLTPQQGAELTTESGRSPHPNTHTLSSDPTVTKLNFDKDRTPGSKHYSLVSIREKLP--EEKIPSTEQVQDALSSFDFLNDRISLSVKPELKDVTQHQIQPPGLELIAVPKNTDIREENDDGEDEEEQFHFSLRDFKCVAVLGRGHFGKVLLAEYSSTGEMFAIKALKKGDIVSRDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRATFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISVMRRLLRRNPERRLGGGERDAEEVKKHLFFRNMDWTGLLGKKVKPPFVPVIQSPSDVSNFDEEFTSEAPVLTPPRDQRPLSREEQE 967

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: zgc:153916 (serine/threonine-protein kinase N2 [Source:NCBI gene;Acc:103027669])

HSP 1 Score: 577.015 bits (1486), Expect = 0.000e+0
Identity = 355/858 (41.38%), Postives = 507/858 (59.09%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDL-GFSSTSTIIFQNALQSKTK--RPGSTFH-----DVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            PD   SET       RLA       IE+ V+ GAE ++Q++  G  KD       +++ ++SK KI+FI  QI +    N+  +             +  DL +E   L++   IE A+  G      L G     ++    +  + + ES QK+ L + S+++ + +LP N        +S+ +  +    +  +  ++S    N+ S +   ++++GTL +  +GC+DL ++ P     A   L G+S + T   +++  S+T   R GS+ +     ++  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R     RS        L A  FL LEDFLD  R+   L L P+G +F++VTF NPV     KL+RQK++FSK++G+  +R  +MN+++  W R++     +V     + SPP      ++  +  S   P P                  AI     P                    P  +++ +K+ Y ++        +         +F+C++VLGRGHFGKVLLA+Y+S G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F EPRAVFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+ DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR P+ RLGA  RDAE+VKK PF R++++  LLAK+++P FVP +   EDVSNFD EFT E PILTP ++  +LT ++Q+
Sbjct:   91 PDTPSSETRTCTNSSRLAALKKQNDIELKVKQGAENMIQMYSNGSYKDRKLLAMAQQMLQDSKTKIEFIRMQILKASQTNESII-------------SPLDLRLE--ELRHHFRIESAVAEGAKNVMKLLGSGKVTEKKAHSEAQARFNESSQKLDLLKFSLEQRLSELPKNHP--KASVISEELAMVASPPQSPRQSIISS--QNQYSTVAKPAALTGTLEVRLMGCQDLLENVPGRSKAASVSLPGWSPSET---RSSFMSRTNKNRAGSSRNLSKADELSNEISAVLKLDNTVVGQTTWKPVSNQSWDQKFTLELDRSRELEISVYWRDY---RS--------LCAVKFLRLEDFLDNQRHGMCLYLEPQGKLFVEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPSV---NNSFSPPV-----AELGSALS---PEPG-----------------AIGHPDSP--------------------PLSRYAEKKACYRIIH------SEYQQLCFSIRDFKCVAVLGRGHFGKVLLAEYRSTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSEPRAVFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYQDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPDRRLGAGERDAEEVKKHPFLRNVDWGALLAKKIQPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRVLTANEQE 861

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: pkn3 (protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131-1902])

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 339/852 (39.79%), Postives = 491/852 (57.63%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLR-----GIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVS-------HPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTS---TIIFQNALQSKTKRPGSTFHD-VQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPA--PNSDFSAGYSMTCPRPSKK-----PDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            ++ L  +L +E+ V+ GAE ++Q +        K+    +++ ++S+ KI+ +  QI +     +   E  D +  +  T++  +L ME   L++   IE A+  G        G +   DR    +  ++ +ES QK+ L + S+++   +LP +               I+E++    S  V           +   S+    +S++G L +  +GC+DL +S P    ++ T     S S   ++  ++ L +++    +   D +  E   VLK+DN+ V  T +R +    W     +++ER++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +V F NPV     KL+RQKR+F K KG+N +R  +MNM+   W R++ S         T +SPP   +  P+     G  +T P  ++K     P    N  V  LN       + P     K  +S E   ++  +    HS++  +    Q   P    +  K L   +F+CISVLGRGHFGKVLLA++KS GK YAIKALKK +++ R+E+++L  EKRIF+TI  S HPFLVNL  CFQ+ +HV FVMEY+ GGDLM HI   IF E +  FYA C++LG++FLH  +IVYRDLKLDNLL+D  G+V++ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS E+  I+++L+++ PE RLGA  +DA +VKK  FF+ ++++ LLAKRVKP F+P +    DVSNFD EFT+ +P+LTP +    L    Q
Sbjct:   31 IRTLRKQLTMELKVKQGAENIMQTYASRSVKDRKMLSTAQQMLQDSRTKIELLRMQIVKVTQAREGEREATDQDGRSSETISPLELRME--ELRHHLRIEAAVAEGAKNVVKQLGGRRVQDRRALAEAQASLQESSQKLDLLRLSLEQRRGELPQDH---------PKRAAIKEELTVGTSPSVGLQKERHHSSSSASSSSFFKPASLTGRLEVRLMGCQDLLESVPGRCRVSCTSSTPGSPSEAKSLRMRSGLSTRSTNGKTAKSDELSTEISAVLKVDNRMVGRTHWRPMGKEAWDQSFIIELERSRELEIGVYWRD------------WRALCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFTEVRFINPVIERHPKLQRQKRIFPKEKGKNFLRAAQMNMNFATWGRLMMSVLPPCSSTITAMSPPLAASDLPSPPLPTGPDLTSPPSAEKTASSTPPPSGNSAVVKLNFSEERPPKPPRLYLTKTPSS-ESPVSMNSK---GHSSEGPKGRAEQHCAP----KKKKGLQMEDFKCISVLGRGHFGKVLLAEHKSTGKMYAIKALKKGDVVTRDEVDSLMCEKRIFETINASHHPFLVNLHGCFQTCDHVCFVMEYSPGGDLMTHIHNSIFTERQTRFYAACVLLGLEFLHQNQIVYRDLKLDNLLMDADGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSTYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSPESVSIIQKLLQKNPEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPTIKTSGDVSNFDEEFTRLKPVLTPPQTPFFLGAEQQ 851

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: pkn2 (serine/threonine-protein kinase N2 [Source:NCBI gene;Acc:103040528])

HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0
Identity = 352/862 (40.84%), Postives = 504/862 (58.47%), Query Frame = 3

Query:  318 VQIQDPDDL-----KSETSLKNLEHRLAIEISVRNGAEKLLQLHKG------KLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSN---SQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFP-----TNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFG--NKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            + ++DP++L      SE  L  L+ ++ IE+ V+ GAE ++Q++        KL    +++ ++S++KI+FI  QI +    ++ + +N+D  + A   ++  DL +E   L +   IE A+  G      + G     ++    +  + + ES QK+ L + S+++ + +LP +   S I  ++ LS +  P        ++ L+S    N  S +   ++++GTL +  +GC+DL +  P     T L L G     + +S +   +  ++ + R  S   D+  E   VLK+DN  V +T ++ +S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+GT+F +VTF NPV     KL+RQK++FSK++G+  +R        P  N  I++    V R   ++S   +           S   P P+                         H   +  H          +R  F+ +  ++ Y        TP  R        +F+C++VLGRGHFGKVLLA+Y S G+ +AIKALKK +I++R+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI TD+F EPRA FYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG  DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  +MRRL+RR PE RLG   RDAE+VKK  FFR++++  LL K+VKP FVP + +  DVSNFD EFT E P+LTP +D+  L+  +Q+
Sbjct:   84 IVVKDPEELLLDTPSSEGRLAALKKQIDIELKVKQGAENMIQMYSNGSSKDRKLLATAQQMLQDSRMKIEFIRMQILKASQSHELSFDNND--VIAKPIISPLDLRVE--ELCHHARIEHAVAEGAKNVMKILGSGKLTEKKTHSEAQARFNESSQKLDLLKYSLEQRLSELPKHHPKSSIIMEE-LSLMSSPALS----PRNSLIS--TQNPYSTIAKPAALTGTLDVRLMGCQDLLEDVPGRSKATTLTLPGWSPSDTRSSFMSRGSRSRTASIRNLSKTDDLSNEISAVLKLDNTVVGQTSWKPVSNQSWDQKFTLELDRSRELEISVYWRD------------WRSLCALKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRTKLQRQKKIFSKQQGRTFLR-------APQMNINIATWGRLVRRAIPSVSNSNLTPQQGAELTTESGRSPHPNT------------------------HTLSRYAHT---------DRVTFRAALCENLYFF------TPVLR--------DFKCVAVLGRGHFGKVLLAEYSSTGEMFAIKALKKGDIVSRDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRATFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISVMRRLLRRNPERRLGGGERDAEEVKKHLFFRNMDWTGLLGKKVKPPFVPVIQSPSDVSNFDEEFTSEAPVLTPPRDQRPLSREEQE 868

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 277.715 bits (709), Expect = 9.707e-83
Identity = 141/311 (45.34%), Postives = 211/311 (67.85%), Query Frame = 3

Query: 1857 KLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTD-IFEEPRAVFYAGCIVLGIDFLHSKK-IVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTP 2783
            K+  NNF  + +LG+G FGKV+L + K+ G+YYA+K LKK  I+A++E+    +E R+ QT   +KHPFL  L   FQ+ + + FVMEY  GG+L  H+  + +F E R  FY   IV  +D+LH++K +VYRDLKL+NL+LD+ G++K+ADFGLCKE +  G    TFCGTPE+LAPEVL + DY R+VDWWGLGV++YEM+ G  PF   + E++F+ I+  +IR+PR LS +A  ++  L+++ P+ RLG    DA+++ +  FF  + + D+  +++ P F P++A+E D   FD EFT +   +TP
Sbjct:  144 KVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQT---TKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDEEFTAQTITITP 451

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 268.855 bits (686), Expect = 5.669e-79
Identity = 141/297 (47.47%), Postives = 198/297 (66.67%), Query Frame = 3

Query: 1836 PQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQ-TDIFEEPRAV--FYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKL 2717
            P      KL  ++F  + VLG+G FGKV+LA+ K  GK++AIKALKK  +L  +++E    EKR+     E  HPFL +L   FQ+ EH+ FVME+  GGDLM HIQ    F+ P     FYA  ++ G+ FLHS  I+YRDLKLDN+LLD +G+VK+ADFG+CKE++G G+  +TFCGTP+++APE+L+ R Y  SVDWW +GVLIYEML+G+ PF G +E+E+F++I  H   YPR LS  +  I+  L  R    RLGA      D++  PFF+++++  L A+++ P F PK+
Sbjct:  239 PSGEIAGKLSLDHFHLLKVLGKGSFGKVMLAELKEQGKFFAIKALKKEVVLMGDDVECTMVEKRVLLMACE--HPFLTHLCGTFQTKEHLFFVMEFLTGGDLMFHIQDKGKFDLPTGTNRFYAAEVICGLQFLHSHNIIYRDLKLDNVLLDREGHVKIADFGMCKEHVGAGNLATTFCGTPDYIAPEILLGRAYGTSVDWWSMGVLIYEMLIGQSPFYGSDEDELFEAIKGHTPHYPRWLSDSSRNILSCLFERDHTKRLGAVG----DIRLHPFFKNIDWPSLEARKITPPFKPKV 529

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 243.817 bits (621), Expect = 2.000e-73
Identity = 116/244 (47.54%), Postives = 167/244 (68.44%), Query Frame = 3

Query: 1995 NELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQT-DIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLAN 2723
            +++E    EKRI        HP+L +L S FQ+ EH++FVMEY  GGDLM HIQ    FE  RA FYA  IV G+ FLH + I+YRDLKLDN+LLD+ G+VK+ADFG+CKEN+    R  TFCGTP+++APE+++ + Y  SVDWW  GVL+YEML+G+ PF GD+EEE+F+SI      YPR ++ ++  I+  L+ R P  RLG +     ++++ PFFR++N++ L  + ++P F P++ +
Sbjct:   29 DDVECTLVEKRILSL--AWGHPYLAHLYSTFQTKEHLMFVMEYLNGGDLMFHIQVKGRFEIDRATFYAAEIVSGLQFLHDQGIIYRDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEIVIGQKYNCSVDWWSFGVLLYEMLIGQSPFRGDDEEELFESIRTSVPYYPRWITKDSRDILPLLLEREPMKRLGVTG----EIRQHPFFRTINWEALEKRELEPPFKPRVVS 266

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 242.662 bits (618), Expect = 6.109e-71
Identity = 131/300 (43.67%), Postives = 195/300 (65.00%), Query Frame = 3

Query: 1869 NNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQ-TDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQE 2765
            ++F  ++VLG+G FGKVLLA++KS+G +YA+K +KK+ IL + E + + +E+ +   +   +HPFLV L   FQS + + FVM+Y  GG+L  H+Q    F E RA FYA  I   I +LHS  IVYRDLK +N+LLD QG++ + DFGLCKE +     T TFCGTPE+LAPEVL +  Y R+VDWW LG ++YEML G  PF   N +++++SI++  ++     +  A  ++  L+ + P  RLGA++ D  ++K   FF ++N++DL AKR+   + P ++   D+ NFD  FT E
Sbjct:   90 SDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVL--VKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATS-DILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAE 386

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 206.453 bits (524), Expect = 5.091e-60
Identity = 100/251 (39.84%), Postives = 152/251 (60.56%), Query Frame = 3

Query: 1998 ELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQ-TDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFD 2747
            ++E   +EKRI Q I+    PFLV L   F+   ++  V+EY  GG++  H++    F EP + FYA  IVL  ++LHS  ++YRDLK +NLL+D+QGY+++ DFG  K   G   RT T CGTPE+LAPE+++ + Y ++VDWW LGVLIYEM  G  PF  D   +I++ IV+ ++R+P H S +   ++R L++     R G       D+K   +F + ++  +  ++V+  F+PK     D SNFD
Sbjct:   22 QVEHTLNEKRILQAIS---FPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFD 266

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: PKC1 (Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201])

HSP 1 Score: 325.479 bits (833), Expect = 5.087e-94
Identity = 167/394 (42.39%), Postives = 256/394 (64.97%), Query Frame = 3

Query: 1647 DIDHNKVVTDLNALAIADTQKPHYEKK--KQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            D  H     D+N+      ++ H  K+  ++  S+   +    R   Q S QKS+ +     K    KR  +K+  +NF  + VLG+G+FGKV+L++ K+  +  AIK LKK  I+  +++E+  +EK++F   T++KHPFL NL   FQ+   + F ME+  GGDLM H+Q       RA FYA  ++L + + H   ++YRDLKL+N+LL  +G++K+AD+GLCK+ M +G+RTSTFCGTPEF+APE+L E++YT++VDWW  GVL+Y+ML+ + PF GD+E+E+F++I+  E  YP  ++ E   I + L+ + PE RLGA  RDA++V ++PFFR++NFDD+L  RVKP ++P++ + ED S F+ EFT   P LTP    ++LT S Q+
Sbjct:  749 DSTHTNPFRDMNSETF-QIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKR--RKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLP--SVLTTSQQE 1137

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609])

HSP 1 Score: 231.106 bits (588), Expect = 1.381e-64
Identity = 129/324 (39.81%), Postives = 201/324 (62.04%), Query Frame = 3

Query: 1854 KKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDI-FEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            K L  ++F  + V+G+G FGKV+  + K   K YA+KA++K+ I++++E+    +E+ +   +     PF+V L   FQS E + FV+ +  GG+L  H+Q +  F+  RA FY   ++  +D LH   +VYRDLK +N+LLD QG++ + DFGLCK NM   D+T TFCGTPE+LAPE+L+   YT++VDWW LGVL+YEML G  P+  ++  +++  I+   + +P     +A  ++  L+ R P  RLG +   A++++  PFF  L++  LL K   P + P ++N  D SNFD EFT+E+PI +   +   L+ES QK
Sbjct:  340 KPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARV---DCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYNG--ADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDE--YLSESVQK 656

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710])

HSP 1 Score: 222.631 bits (566), Expect = 9.061e-62
Identity = 120/308 (38.96%), Postives = 189/308 (61.36%), Query Frame = 3

Query: 1854 KKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDI-FEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPI 2774
            K L  ++F  + V+G+G FGKV+  + K   K YA+KAL+KA I+++ E+    +E+ +   +     PF+V L   FQS E +  V+ +  GG+L  H+Q +  F   R+ FY   ++  +D LH   ++YRDLK +N+LLD QG++ + DFGLCK NM   D+T TFCGTPE+LAPE+L+ + YT++VDWW LG+L+YEM+ G  P+  +N   ++  I+   + +P      A  ++  L+ R P  RLG +  D  +++  PFF+ +++  LL K   P + P + +E D +NFD EFT+E+PI
Sbjct:  337 KPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARV---DCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVNGTD--EIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPI 639

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 214.542 bits (545), Expect = 1.377e-61
Identity = 118/310 (38.06%), Postives = 187/310 (60.32%), Query Frame = 3

Query: 1827 KPTPQKR-TTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHI-QTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKL-ANEEDVSNFD 2747
            KP  Q R T+ K   ++F+ +  LG G FG+V L +   NG++YA+K LKK  I+   ++E    E+R+   ++   HPF++ +   FQ ++ V  VM+Y  GG+L   + ++  F  P A FYA  + L +++LHSK I+YRDLK +N+LLD+ G++K+ DFG  K      D T T CGTP+++APEV+  + Y +SVDWW  GVLIYEML G  PF   N  + +++I+N E+++P     +A  ++++L+ R    RLG     +EDVK  P+F  + ++ LLA+ ++  + P +   + D S FD
Sbjct:   71 KPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVS---HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV---PDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFD 374

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700])

HSP 1 Score: 213.001 bits (541), Expect = 3.647e-61
Identity = 118/330 (35.76%), Postives = 191/330 (57.88%), Query Frame = 3

Query: 1764 QERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHI-QTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKL-ANEEDVSNFD 2747
            QE+P+  H T  +E    Q I     + T+ K    +F+ +  LG G FG+V L + + NG+YYA+K LKK  ++   ++E    E+ +   +T   HPF++ +   FQ  + +  +M+Y  GG+L   + ++  F  P A FYA  + L +++LHSK I+YRDLK +N+LLD+ G++K+ DFG  K      D T T CGTP+++APEV+  + Y +S+DWW  G+LIYEML G  PF   N  + ++ I+N E+R+P   + +   ++ RL+ R    RLG      EDVK  P+F+ + ++ LL++ ++  + P +   + D S FD
Sbjct:   52 QEKPKQPHVTYYNEEQYKQFIAQA--RVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVT---HPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV---PDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFD 373

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO43312 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYZ0])

HSP 1 Score: 565.074 bits (1455), Expect = 0.000e+0
Identity = 356/849 (41.93%), Postives = 498/849 (58.66%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQLH-------KGKLKDETRRLYEESKIKIQFIENQINRHKH--PNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIK----ATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQ-SNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHD--VQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNK--LKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIIS-SGNATVLRKYTTISPPTMPAPNSDFSAGY-SMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPH---YEKKKQHA-SMEDLTNLQERPQFQHSTQ-KSEYAVMQPIK---PTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLV-ERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            L +L+ +LA+E  V+ GAE +L ++       K KL  E +++ E++K K++ I   I R +    N+D V N D    A        +E+ I ++++   IE  ++ G    +K    +  D+N  ++    + ES QK+ L Q S+QK + +L       G         P      ++  + V   +  +Q +++T  ++++G L +  +G  ++    P            S       Q    SK K   + + D  +  E   VLK+DN  V +T ++     CW     +++++++ELEV +Y R     RS        L   +F  LE+FLD   +K  + L P+G +F +VTF NP+   K  L+RQK+LF   KG+N +R  +MN +V  W R++  +  A      T +SP      NS   A Y  +T   P  +P    NK  +        D Q P     E++ Q A S     +    P  Q     KS      P++   P+P   T+  +  +NFRCISVLGRGHFGKV+LA+Y++  + +AIKALKK +I+AR E+E+L +EKRIF T  +++HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F E R VFY  C+VLG+ +LH  +IVYRDLKLDNLLLD +GYVK+ADFGLCKE+MG+G RT TFCGTPEFLAPE+LV E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLGA+ +DAE+VKKQPFFR + +DDLLA++++P FVP++ + EDVSNFD EFT E PILTP K+   L   +Q
Sbjct:  107 LDSLQKQLAVENKVKQGAENMLAMYANAKSKDKAKLVAEAQQMLEDAKTKMEIIRMAILREQQVATNEDGVANKDT---AAPGEGLLPIELRIEDVRHHIDIESRVIQGAKNMMKFLQKSGQDKNSLQEAEKRFHESSQKLDLLQCSLQKLMAELSPEQAAVGIYKDERFGTPP----SYADRKAVG--LGRQQYTSITKPAALTGQLNVLLVGAHNILTVVPNRDPRKSASFAMSPDGKFEQQRG-SSKRKSGYNKWGDETLSTELCAVLKLDNTYVGQTMWKTAGSQCWQQQFTIELDKSRELEVGVYWRD---HRS--------LCGVAFFRLEEFLDNQEHKIKVPLEPQGLLFAEVTFLNPMVTRKPKLQRQKKLFHIHKGKNFLRAGQMNTNVATWARLLKRAAPANCTTNSTALSP------NSASQAPYQGLTATPPRSQPYTPDNKAKSPNTYTPTIDNQTPPKRPAEREVQDALSAFGFLDSPGSPSIQQPHPVKSRPPPPIPVRHRAPSPPSNTSH-MSMSNFRCISVLGRGHFGKVILAEYRNTNELFAIKALKKGDIIAREEVESLLAEKRIFLTANKTRHPFLVNLFACFQTQEHVCFVMEYAPGGDLMMHIHADVFAESRTVFYTACVVLGLQYLHDHEIVYRDLKLDNLLLDSEGYVKIADFGLCKEDMGYGARTGTFCGTPEFLAPEMLVTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIAIMRRLLRRNPERRLGAAEKDAEEVKKQPFFRDMRWDDLLARKIRPPFVPQVKHAEDVSNFDEEFTSEEPILTPPKEARSLNPDEQ 927

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO35585 (Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7SL27])

HSP 1 Score: 297.745 bits (761), Expect = 4.239e-87
Identity = 154/330 (46.67%), Postives = 221/330 (66.97%), Query Frame = 3

Query: 1839 QKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQ-TDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAE-DVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            ++   +K+   +F  I VLG+G FGKVLLA+ K   + YAIK LKK  +L  +++E    E+R+      + HPFL +L S FQ+ E + FVMEY  GGDLM  IQ +  F+E R+ FYA  +VL + FLH   ++YRDLKLDN+LLD  G++K+ADFG+CKENM  G  T+TFCGTP+++APE+L E+ Y  SVDWW LGVL+YEM+ G+ PF  +NEE++F+SI++ ++ YP  LS EA  I++  M +    RLG +    E  +++  FFR +NF+ L A+++ P F PK+ +  DV NFD++FT+E P LTP  DR ++   DQ+
Sbjct:  371 RRHVLRKMTLKDFTFIKVLGKGSFGKVLLAERKGTDEVYAIKILKKESVLQDDDVECTMIERRVLAL--SAGHPFLTSLHSSFQTVERLFFVMEYVNGGDLMFQIQKSRKFDENRSRFYAAEVVLALQFLHQNGVIYRDLKLDNVLLDADGHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQPYGFSVDWWALGVLMYEMMAGQPPFEAENEEDLFESILHDDVLYPVWLSREAVSILKGFMTKNYLKRLGCTPTSTESSIREHAFFRLINFEKLEARQINPPFKPKIRSRTDVGNFDTDFTKEEPKLTPT-DRNVIVNIDQR 697

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521])

HSP 1 Score: 254.218 bits (648), Expect = 8.134e-75
Identity = 132/326 (40.49%), Postives = 207/326 (63.50%), Query Frame = 3

Query: 1854 KKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXX---XXXXXXXXXXXRNELETL--TSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTD-IFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTES 2813
            +K+   +F  + VLG+G +GKV L + K++G          + K   + R++ +T    +E+ I + +   KHPF+V+L+  FQ+   +  ++EY  GG+L M ++ + IF E  A FY   I + ++ LH + IVYRDLK +N+LLD  G+VK+ DFGLCKE++     T TFCGT E++APE+L    + ++VDWW LG L+Y+ML G  PF  DN ++  D I+  ++  P +L+ EA   +R+L++R P+ RLG  A DA  +K   FFR + ++DLLAK+V+P F P ++ EEDVS FDS+FT++ P+ +P  D ++L+ES
Sbjct:   58 EKVGPESFELLKVLGKGGYGKVFLVK-KNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECV---KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFDSKFTRQTPVDSP--DDSMLSES 377

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO44938 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU22])

HSP 1 Score: 255.373 bits (651), Expect = 1.405e-73
Identity = 141/342 (41.23%), Postives = 202/342 (59.06%), Query Frame = 3

Query: 1827 KPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDI-FEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPF--------PGDNEEE-IFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDA-EDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            K  P       +  N+F  I V+GRG + KV+L + K   + YA+K +KK  +    +++ + +EK +F+    S HPFLV L SCFQ++  + FV+EY  GGDLM H+Q      E  A FY+  I   ++FLH K ++YRDLKLDN+LLD  G++K+ D+G+CKE +  GD TSTFCGTP ++APE+L   DY  SVDWW LGVL+YEML G  PF        P  N E+ +F  I+   IR PR LS++A  I++  + + P  RLG   +    D+    FFR+++++ L A++V P F P+  +   + NFD +FT E    TP  D  +L   DQ
Sbjct:  206 KRKPGSGAGALISVNDFNLIRVIGRGSYAKVMLVELKKTKRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQ--ASNHPFLVGLHSCFQTSSRLFFVIEYVSGGDLMYHMQRQRRLPEDHARFYSAEICCALNFLHEKGVIYRDLKLDNVLLDSDGHIKLTDYGMCKEGIRPGDVTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIVGSADNPDQNTEDYLFQVILEKPIRIPRSLSVKAASILKGYLNKNPTERLGCHPQTGFADITSHAFFRTVSWEQLEARQVTPPFKPRQEDPYGLENFDPQFTNEDVQFTP-DDPKMLETIDQ 544

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2])

HSP 1 Score: 246.514 bits (628), Expect = 3.113e-72
Identity = 128/301 (42.52%), Postives = 197/301 (65.45%), Query Frame = 3

Query: 1869 NNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIF-QTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTD-IFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQE 2765
            ++F  + V+G+G FGKV L++ K   K+YAIK L K+ I  RNE + + +E+ +  Q +T   HPFLV L   FQ+ + + FV++Y  GG+L  H+Q +  F E RA FYA  I   I +LH  +I+YRDLK +N+LLD +G++ + DFGLCKE +     TSTFCGTPE+LAPEVL ++DY +SVDWW LG ++YEM+ G  PF   +  E++D+I++  +R   ++S  A  I+  L+++    RLG+   D ED++   FFRS+N+  L+A+ ++P + P ++ + D+ +FD EF +E
Sbjct:   72 SDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVT---HPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVRE 369

[Close]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: pkn2 (protein kinase N2 [Source:NCBI gene;Acc:101158798])

HSP 1 Score: 581.637 bits (1498), Expect = 0.000e+0
Identity = 366/883 (41.45%), Postives = 513/883 (58.10%), Query Frame = 3

Query:  333 PDDLKSETSLKNLEHRLA-------IEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDL-GFSSTST----IIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGW-VLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNK--LKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQER--------PQFQHSTQKS------------------EYAVMQPIKPTPQKRTTKKLDWN--NFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            PD   SE  + +   RLA       IE+ V+ GAE ++ ++  G  KD       +++ ++SK KI+FI  QI +     + + E    E+     ++  DL +E   L +   IE A+  G      L G     ++    +  + + ES QK+ L + S++  + +LP +       S+ + +  +       +S  +S    N+ S +T  ++++GTL +  +GC+DL ++ P  L  A   L G+S + T    I   N  +S + R  +   ++  E   VLK+DN  V +T +R  S+  W     L+++R++ELE+ +Y R             W  L A  FL LEDFLD  R+   L L P+G +F +VTF NPV   +  L+RQK++FSK++G+  +R  +MN+++  W R++     TV     + SP      +S          P P   P      +VT L+          HY   +       L NL +           F   ++++                  E  V +P    P+ R  ++  ++  +FRC++VLGRGHFGKVLLA+YKS G+ +AIKALKK +I+AR+E+++L  EKRIF+T+   +HPFLVNL +CFQ+ EHV FVMEYA GGDLMMHI  D+F EPRAVFYA C+VLG+ FLH  KIVYRDLKLDNLLLD +GYVK+ADFGLCKE MG+ DRTSTFCGTPEFLAPEVL E  YTR+VDWWGLGVLI+EMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR+PE RLGA  +DAE+VKK PFFR++++  LLAK+VKP FVP + +  DVSNFD EFT E PILTP ++  +L   +Q
Sbjct:  113 PDTPNSEARMTSSSSRLAALKRQNDIELKVKQGAENMIHMYSNGSSKDRKLLATAQQMLQDSKTKIEFIRMQILKASQETELSFETS--EVMDKPIISPLDLRVE--ELCHHARIESAVAEGAKNVMKLLGSGKVTEKKAHLEAQARFNESSQKLDLLRHSLELRLNELPKSDP--RSHSIIEELSLLSSPALSPRSSFIS--TQNQYSTVTKPAALTGTLDVRLMGCQDLLENIPGRLKTASVVLPGWSPSETRSSFISRANRNRSVSSRNLAKSEELSNEISAVLKLDNTVVGQTNWRPASNQAWDQKFTLELDRSRELEISVYWRD------------WRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGMLFAEVTFFNPVIERRPRLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTV--STNSFSPQGAETGHSSLPGS-----PTPCSDP------LVTKLDFDKEPTPGPKHYPASEVAVEPPALLNLPDNKDEVRNALSSFDFLSKRNSVVMNPDILDQNFQDPELELPVHKPRDVDPEIRDDEQFQFSLQDFRCVAVLGRGHFGKVLLAEYKSTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTPEHVCFVMEYAAGGDLMMHIHADVFSEPRAVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRSPERRLGAGEKDAEEVKKHPFFRNMDWGGLLAKKVKPPFVPTIQDANDVSNFDEEFTSEAPILTPPREPRMLNSEEQ 962

[Close]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: ENSORLT00000020420.2 (serine/threonine-protein kinase N1 [Source:NCBI gene;Acc:101159676])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 354/870 (40.69%), Postives = 502/870 (57.70%), Query Frame = 3

Query:  321 QIQDPDDLKSETS----------LKNLEHRLAIEISVRNGAEKLLQLH-KGKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKP--IEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTS--------TIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVF--GNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQ---KRTTKK-LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            Q ++ DD KS  S          +  LE +L IE+ V+ GAE ++ ++  G  KD+      +++ ++SK KI  I  QI +       A++  +   D     + C +E+ +  L +   +E A+  G      L G     D+    +       S Q++ L + ++++ +Q+LP       D     L+K   +        S   +  + N+ S L+  S ++GTL +  LGC  L +  P     A   L   STS        + ++  +  S + +  S   ++  E   VLK++N  V +T +R + +  W     L++ER++E+E+ +Y R   +           L A  +L LEDFLD  R++  L L P+G +  +VTF NPV   G +L+RQK++FSK+ G+  +R  +MN+D+  W R++   NA           P+   P S F++      P             V  LN     D+  P   + ++  S ED+  L + P  +        A  QP +   Q   +R ++  +   +F+ ++VLGRGHFGKVLL++YK  G  +AIKALKK +I+AR+E+E+L  EKRIF+T+  S HPFLVNL +CFQ+ EHV FVMEY  GGDLMMHI  D+F EPRAVFY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+  +DAEDVKKQPFFR+ +++ LL ++V P FVP +  +EDVSNFD+EFT E   LTP ++R  L++ +Q
Sbjct:  125 QEENKDDSKSPGSVNRTSANQHRIAALERQLNIELKVKQGAENMIPIYASGGTKDKKLLQTAQQMLQDSKTKIDIIRMQIRK-------AMQATEQSEDNQSKPDLCGVELRVEELWHHYRVEHAMAEGAKNMLRLLGAGKVQDKKAINEAQCGLSGSSQRLDLLRCALEQRLQELPE------DHPKVCLIKEELVLASSSAFSSSHSTPYVHNQYSTLSKPSPLTGTLQVRLLGCVGLLEVVPGRSKGAPVVLPSYSTSDGRPSFKLSGLYSRSTSSMSLKIPSKNEELSSEVSAVLKLENTVVGQTAWRTVGEQAWDQSFTLELERSREMEIAVYWRDYRS-----------LCALKYLKLEDFLDNQRHQVQLELEPQGLLVAEVTFFNPVIERGRRLQRQKKVFSKQHGKAFLRARQMNVDIATWVRLLR--NAI----------PSGSNPPSLFTSNTLSQAP---------GEISVEKLNL----DSDSPSRAEVRREWSTEDVAPLDQTPVIEAPPTAEVPAHKQPARSPSQNSLRRASRGPVSLQDFKLLAVLGRGHFGKVLLSEYKKTGGLFAIKALKKGDIVARDEVESLMCEKRIFETVNGSHHPFLVNLFACFQTPEHVCFVMEYTAGGDLMMHIHADVFAEPRAVFYSACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRRLLRRNPERRLGSGEKDAEDVKKQPFFRNTDWEGLLHRKVSPPFVPTIVGKEDVSNFDAEFTAEPAALTPPRERRTLSQKEQ 945

[Close]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: ENSORLT00000032181.1 (serine/threonine-protein kinase N1 [Source:NCBI gene;Acc:101159676])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 353/870 (40.57%), Postives = 501/870 (57.59%), Query Frame = 3

Query:  321 QIQDPDDLKSETS----------LKNLEHRLAIEISVRNGAEKLLQLH-KGKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKP--IEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTS--------TIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVF--GNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQ---KRTTKK-LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            Q ++ DD KS  S          +  LE +L IE+ V+ GAE ++ ++  G  KD+      +++ ++SK KI  I  QI +     + + +N           + C +E+ +  L +   +E A+  G      L G     D+    +       S Q++ L + ++++ +Q+LP       D     L+K   +        S   +  + N+ S L+  S ++GTL +  LGC  L +  P     A   L   STS        + ++  +  S + +  S   ++  E   VLK++N  V +T +R + +  W     L++ER++E+E+ +Y R   +           L A  +L LEDFLD  R++  L L P+G +  +VTF NPV   G +L+RQK++FSK+ G+  +R  +MN+D+  W R++   NA           P+   P S F++      P             V  LN     D+  P   + ++  S ED+  L + P  +        A  QP +   Q   +R ++  +   +F+ ++VLGRGHFGKVLL++YK  G  +AIKALKK +I+AR+E+E+L  EKRIF+T+  S HPFLVNL +CFQ+ EHV FVMEY  GGDLMMHI  D+F EPRAVFY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+  +DAEDVKKQPFFR+ +++ LL ++V P FVP +  +EDVSNFD+EFT E   LTP ++R  L++ +Q
Sbjct:  199 QEENKDDSKSPGSVNRTSANQHRIAALERQLNIELKVKQGAENMIPIYASGGTKDKKLLQTAQQMLQDSKTKIDIIRMQIRKAMQATEQSEDNQSKP-------DLCGVELRVEELWHHYRVEHAMAEGAKNMLRLLGAGKVQDKKAINEAQCGLSGSSQRLDLLRCALEQRLQELPE------DHPKVCLIKEELVLASSSAFSSSHSTPYVHNQYSTLSKPSPLTGTLQVRLLGCVGLLEVVPGRSKGAPVVLPSYSTSDGRPSFKLSGLYSRSTSSMSLKIPSKNEELSSEVSAVLKLENTVVGQTAWRTVGEQAWDQSFTLELERSREMEIAVYWRDYRS-----------LCALKYLKLEDFLDNQRHQVQLELEPQGLLVAEVTFFNPVIERGRRLQRQKKVFSKQHGKAFLRARQMNVDIATWVRLLR--NAI----------PSGSNPPSLFTSNTLSQAP---------GEISVEKLNL----DSDSPSRAEVRREWSTEDVAPLDQTPVIEAPPTAEVPAHKQPARSPSQNSLRRASRGPVSLQDFKLLAVLGRGHFGKVLLSEYKKTGGLFAIKALKKGDIVARDEVESLMCEKRIFETVNGSHHPFLVNLFACFQTPEHVCFVMEYTAGGDLMMHIHADVFAEPRAVFYSACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRRLLRRNPERRLGSGEKDAEDVKKQPFFRNTDWEGLLHRKVSPPFVPTIVGKEDVSNFDAEFTAEPAALTPPRERRTLSQKEQ 1019

[Close]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: ENSORLT00000033811.1 (serine/threonine-protein kinase N1 [Source:NCBI gene;Acc:101159676])

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 354/870 (40.69%), Postives = 502/870 (57.70%), Query Frame = 3

Query:  321 QIQDPDDLKSETS----------LKNLEHRLAIEISVRNGAEKLLQLH-KGKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKP--IEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTS--------TIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVF--GNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQ---KRTTKK-LDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            Q ++ DD KS  S          +  LE +L IE+ V+ GAE ++ ++  G  KD+      +++ ++SK KI  I  QI +       A++  +   D     + C +E+ +  L +   +E A+  G      L G     D+    +       S Q++ L + ++++ +Q+LP       D     L+K   +        S   +  + N+ S L+  S ++GTL +  LGC  L +  P     A   L   STS        + ++  +  S + +  S   ++  E   VLK++N  V +T +R + +  W     L++ER++E+E+ +Y R   +           L A  +L LEDFLD  R++  L L P+G +  +VTF NPV   G +L+RQK++FSK+ G+  +R  +MN+D+  W R++   NA           P+   P S F++      P             V  LN     D+  P   + ++  S ED+  L + P  +        A  QP +   Q   +R ++  +   +F+ ++VLGRGHFGKVLL++YK  G  +AIKALKK +I+AR+E+E+L  EKRIF+T+  S HPFLVNL +CFQ+ EHV FVMEY  GGDLMMHI  D+F EPRAVFY+ C+VLG+ FLH  KIVYRDLKLDNLLLD +G+VK+ADFGLCKE MG GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+  +DAEDVKKQPFFR+ +++ LL ++V P FVP +  +EDVSNFD+EFT E   LTP ++R  L++ +Q
Sbjct:  103 QEENKDDSKSPGSVNRTSANQHRIAALERQLNIELKVKQGAENMIPIYASGGTKDKKLLQTAQQMLQDSKTKIDIIRMQIRK-------AMQATEQSEDNQSKPDLCGVELRVEELWHHYRVEHAMAEGAKNMLRLLGAGKVQDKKAINEAQCGLSGSSQRLDLLRCALEQRLQELPE------DHPKVCLIKEELVLASSSAFSSSHSTPYVHNQYSTLSKPSPLTGTLQVRLLGCVGLLEVVPGRSKGAPVVLPSYSTSDGRPSFKLSGLYSRSTSSMSLKIPSKNEELSSEVSAVLKLENTVVGQTAWRTVGEQAWDQSFTLELERSREMEIAVYWRDYRS-----------LCALKYLKLEDFLDNQRHQVQLELEPQGLLVAEVTFFNPVIERGRRLQRQKKVFSKQHGKAFLRARQMNVDIATWVRLLR--NAI----------PSGSNPPSLFTSNTLSQAP---------GEISVEKLNL----DSDSPSRAEVRREWSTEDVAPLDQTPVIEAPPTAEVPAHKQPARSPSQNSLRRASRGPVSLQDFKLLAVLGRGHFGKVLLSEYKKTGGLFAIKALKKGDIVARDEVESLMCEKRIFETVNGSHHPFLVNLFACFQTPEHVCFVMEYTAGGDLMMHIHADVFAEPRAVFYSACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRRLLRRNPERRLGSGEKDAEDVKKQPFFRNTDWEGLLHRKVSPPFVPTIVGKEDVSNFDAEFTAEPAALTPPRERRTLSQKEQ 923

[Close]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: pkn1a (protein kinase N1 [Source:NCBI gene;Acc:101164700])

HSP 1 Score: 550.051 bits (1416), Expect = 2.168e-178
Identity = 348/845 (41.18%), Postives = 492/845 (58.22%), Query Frame = 3

Query:  360 LKNLEHRLAIEISVRNGAEKLLQLHK-GKLKDE-----TRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGC-----LRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKP---IEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLG-FSSTSTIIFQNALQSKTKRPGSTF-------HDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGN--KLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPS-KKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            +  LE +L IE+ V+ G E ++ ++  G  KD+      +++ ++SK KI  I  QI +       AV+  +   D     + C +E+ I  L++   +E A+  G      L G     D+    +  S   E+ Q++ L + S+ + + +LP       D   ++++K    +     FS SR  +  + N+ S L   S ++GTL +  LGC  L ++ P     +   L  +S   +  F  + +    R GS          ++  E   VLK+DN  V +T +R + +  W     +++ER++E+E+ +Y R   +           L A  +L LE+FLD  +++  + L P+G +  +VTF NPV     +L+RQK++FSK++G+  +R  +MN+D+  W R++ +                   P ++ S  YS T    S    +I   K+  D +     D     Y++     + + L  +   P         E  V  P   + QK+    L   +FR I+VLGRGHFGKVLL++YK  G  YAIKALKK +I+AR+E+++L  EKRIF+ +  S HPFL+NL +CFQ+++HV FVMEY  GGDLMMHI TD+F EPRAVFYA C+VLG+ FLH  KIVYRDLKLDNLLLD  GYVK+ADFGLCKE MG+GDRTSTFCGTPEFLAPEVL +  YTR+VDWWGLGVLIYEMLVGE PFPGD+EEE+FDSIVN E+RYPR LS EA  IMRRL+RR PE RLG+  +DAE+VKKQPFFRS++++ LL ++V P FVP +  +EDVSNFD EFT E P LTP ++   LT  DQ
Sbjct:  127 IAALERQLNIELKVKQGVENMIPIYANGSTKDKKMLQTAQQMLQDSKTKIDIIRMQIRK-------AVQATEHSDDTQGNQDLCGVELRIEELRHHYRVEHAVAEGAKNVLRLLGASKVQDKKALSEAQSRLGEASQRLDLLRDSLDRRLAELPE------DHPKANVIKEELVLAASPAFS-SRHGAPYLHNQYSTLNKPSPLTGTLQVQLLGCVGLLETVPGRSKGSAVTLPCYSPGDSRSFMRSSKGLYGRTGSVSGKTPNKSDELSTEVSAVLKLDNGVVGQTAWRTVGEQAWDQTFTVELERSREMEIAVYWRDFRS-----------LCALKYLKLEEFLDNQKHRVQVELEPQGLLLAEVTFFNPVIERVPRLQRQKKVFSKQQGKAFLRARQMNVDIGTWVRLLRNA-----------------IPTANNSGTYSPTAHSLSLNSGEISVEKLSLDSDTPLRGD-----YKRDTDQQTPDTLPVIDSLPP---RDLLPESPVRTPSANSRQKKGP--LSLQDFRLIAVLGRGHFGKVLLSEYKKTGTMYAIKALKKGDIIARDEVDSLMCEKRIFEIVNMSHHPFLINLFACFQTSQHVCFVMEYTAGGDLMMHIHTDVFTEPRAVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTDGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRRLLRRNPERRLGSGEKDAEEVKKQPFFRSVDWEALLQRKVPPPFVPSIRGKEDVSNFDEEFTTEPPTLTPPREARSLTRKDQ 919

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000065035.1 (SMESG000065035.1)

HSP 1 Score: 1769.98 bits (4583), Expect = 0.000e+0
Identity = 886/886 (100.00%), Postives = 886/886 (100.00%), Query Frame = 3

Query:  165 MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYXXXXXXXXXXXXXXXQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYKIKIDDLDDDILILKQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK
Sbjct:    1 MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYKIKIDDLDDDILILKQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 886

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000065035.1 (SMESG000065035.1)

HSP 1 Score: 1759.58 bits (4556), Expect = 0.000e+0
Identity = 886/899 (98.55%), Postives = 886/899 (98.55%), Query Frame = 3

Query:  165 MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYXXXXXXXXXXXXXXXQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQ-------------IEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYKIKIDDLDDDILILKQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQ             IEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK
Sbjct:    1 MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYKIKIDDLDDDILILKQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQTLKKPNPTLHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 899

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000065035.1 (SMESG000065035.1)

HSP 1 Score: 1727.61 bits (4473), Expect = 0.000e+0
Identity = 871/886 (98.31%), Postives = 871/886 (98.31%), Query Frame = 3

Query:  165 MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYXXXXXXXXXXXXXXXQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYKIKIDDLDDDILILKQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHST               QKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK
Sbjct:    1 MLVPENNSSAVLVDEKRSLNMIKSLNIEITDYKIKIDDLDDDILILKQFEDVQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRLYEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIINLKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQKAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTNLSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSKTKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERAKELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLYPEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNRIISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKVVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHST---------------QKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 871

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000039865.1 (SMESG000039865.1)

HSP 1 Score: 291.197 bits (744), Expect = 5.268e-87
Identity = 161/386 (41.71%), Postives = 242/386 (62.69%), Query Frame = 3

Query: 1665 VVTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVMQPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTD-IFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQ 2819
            V  DLN  ++AD  K  +EK           ++ E  + Q  T ++ Y + Q  +  P+         ++F  I VLG+G FGKV+LA+ K   + YA+K LKK  I+  +++E    EKR+     + K  FLV L SCFQ+ + + FVME+  GGDLM  IQ +  F+EP AVFY   I +G+ FLHSK I+YRDLKLDN++LD +G++K+ADFG+CKE +     T TFCGTP+++APE++  + Y +SVDWW  GV++YEML G+ PF G++EEE+F++I  H + YP+ +S E+  I + L+ + P+ RLG++     DV++  FFR ++++ + A++V+P   PK+ +  DVSNFD EFT+E   LTP  D+  +   DQ
Sbjct:  104 VADDLNVASVADL-KAKFEK-----------SILEEKKNQQITNENNY-INQNKQDIPRA--------SDFNFILVLGKGSFGKVILAERKGTDELYAVKILKKDVIIQDDDVECTMIEKRVLAL--QEKPSFLVQLHSCFQTMDRLYFVMEFVNGGDLMYRIQQEGKFKEPVAVFYTAEIAIGLFFLHSKGIIYRDLKLDNIMLDHEGHIKIADFGMCKEGIFDDKTTRTFCGTPDYIAPEIIKYQPYGKSVDWWAYGVILYEMLAGQAPFDGEDEEELFNAITEHNVSYPKSMSKESVSICKGLLTKDPKKRLGSNRYGDRDVREHLFFRRIDWEKINARQVQPPNKPKIKDPRDVSNFDQEFTKETAQLTPT-DKLFIMNLDQ 465

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000014536.1 (SMESG000014536.1)

HSP 1 Score: 292.352 bits (747), Expect = 2.301e-85
Identity = 144/313 (46.01%), Postives = 206/313 (65.81%), Query Frame = 3

Query: 1884 ISVLGRGHFGKVLLAQYKSNGXXXXXXXXXXXXXXXRNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQERPILTPAKDRALLTESDQK 2822
            ++VLG+GHFGKVLLA+        AIK+++KA      E ++L +E+ I   I +  +PFL+NL+ CFQS  H+ F +EY  GGD M H+    F E  A FY  CIVL  +FLH + I+YRDLKLDN+L+D  GY K+ DFGL K NM    +T+TFCGTPEFLAPE++ E++YTR +DWW LGVL+YEM++GE PFPGD++ EIF  I++      + LS E+T +++RL++R PE RLG        VK+  FF S++++ L ++++ P F+PKL +  D   F+SEFT + P+     D  + +E D +
Sbjct:  340 LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIEHDDEEVDSEFDDE 650

The following BLAST results are available for this feature:

BLAST of Protein kinase N2 vs. Ensembl Human
BLAST of Protein kinase N2 vs. Ensembl Celegans
BLAST of Protein kinase N2 vs. Ensembl Fly
BLAST of Protein kinase N2 vs. Ensembl Zebrafish
BLAST of Protein kinase N2 vs. Ensembl Xenopus
BLAST of Protein kinase N2 vs. Ensembl Mouse
BLAST of Protein kinase N2 vs. UniProt/SwissProt
BLAST of Protein kinase N2 vs. TrEMBL
BLAST of Protein kinase N2 vs. Ensembl Cavefish
BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
BLAST of Protein kinase N2 vs. Ensembl Yeast
BLAST of Protein kinase N2 vs. Ensembl Nematostella
BLAST of Protein kinase N2 vs. Ensembl Medaka
BLAST of Protein kinase N2 vs. Planmine SMEST

BLAST of Protein kinase N2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PKN2	0.000e+0	42.05	protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN1	0.000e+0	41.58	protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN1	0.000e+0	41.58	protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN2	1.433e-168	39.62	protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN3	4.207e-148	37.20	protein kinase N3 [Source:HGNC Symbol;Acc:HGNC:179...	[more]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pkn-1	2.262e-142	36.58	Protein Kinase N (PKN) homolog [Source:UniProtKB/...	[more]
pkn-1	6.267e-141	36.58	Protein Kinase N (PKN) homolog [Source:UniProtKB/...	[more]
pkc-1	1.407e-85	47.44	Protein kinase C-like 1B [Source:UniProtKB/Swiss-...	[more]
pkc-2	5.857e-85	46.73	Protein kinase C-like 2 [Source:UniProtKB/Swiss-P...	[more]
pkc-2	1.175e-84	46.73	Protein kinase C-like 2 [Source:UniProtKB/Swiss-P...	[more]

BLAST of Protein kinase N2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pkn	1.102e-140	69.42	gene:FBgn0020621 transcript:FBtr0088605	[more]
Pkn	4.687e-137	70.63	gene:FBgn0020621 transcript:FBtr0339291	[more]
Pkn	6.437e-137	70.63	gene:FBgn0020621 transcript:FBtr0088601	[more]
Pkn	7.021e-137	70.63	gene:FBgn0020621 transcript:FBtr0088603	[more]
Pkn	9.236e-137	70.63	gene:FBgn0020621 transcript:FBtr0308206	[more]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PKN2	0.000e+0	41.32	zgc:153916 [Source:NCBI gene;Acc:567134]	[more]
PKN2	0.000e+0	41.32	zgc:153916 [Source:NCBI gene;Acc:567134]	[more]
PKN2	0.000e+0	41.32	zgc:153916 [Source:NCBI gene;Acc:567134]	[more]
pkn1a	0.000e+0	42.12	protein kinase N1a [Source:ZFIN;Acc:ZDB-GENE-06120...	[more]
BX321890.2	0.000e+0	39.39	protein kinase N3 [Source:NCBI gene;Acc:323182]	[more]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mgc108147	0.000e+0	42.54	mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914...	[more]
mgc108147	0.000e+0	42.43	mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914...	[more]
mgc108147	0.000e+0	42.57	mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914...	[more]
mgc108147	0.000e+0	42.17	mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914...	[more]
mgc108147	0.000e+0	41.81	mgc108147 protein [Source:Xenbase;Acc:XB-GENE-5914...	[more]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pkn2	0.000e+0	42.74	protein kinase N2 [Source:MGI Symbol;Acc:MGI:10921...	[more]
Pkn2	0.000e+0	42.87	protein kinase N2 [Source:MGI Symbol;Acc:MGI:10921...	[more]
Pkn1	0.000e+0	41.41	protein kinase N1 [Source:MGI Symbol;Acc:MGI:10802...	[more]
Pkn1	0.000e+0	41.41	protein kinase N1 [Source:MGI Symbol;Acc:MGI:10802...	[more]
Pkn2	3.240e-166	40.39	protein kinase N2 [Source:MGI Symbol;Acc:MGI:10921...	[more]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q16513\|PKN2_HUMAN	0.000e+0	42.05	Serine/threonine-protein kinase N2 OS=Homo sapiens...	[more]
sp\|A7MBL8\|PKN2_DANRE	0.000e+0	41.32	Serine/threonine-protein kinase N2 OS=Danio rerio ...	[more]
sp\|Q8BWW9\|PKN2_MOUSE	0.000e+0	42.74	Serine/threonine-protein kinase N2 OS=Mus musculus...	[more]
sp\|A1A4I4\|PKN1_BOVIN	0.000e+0	41.62	Serine/threonine-protein kinase N1 OS=Bos taurus O...	[more]
sp\|Q16512\|PKN1_HUMAN	0.000e+0	41.58	Serine/threonine-protein kinase N1 OS=Homo sapiens...	[more]

BLAST of Protein kinase N2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4Z2DPT2	0.000e+0	39.28	Serine/threonine-protein kinase N2 OS=Schistosoma ...	[more]
A0A2K5H996	0.000e+0	42.79	Protein kinase N2 OS=Colobus angolensis palliatus ...	[more]
A0A2K5H957	0.000e+0	42.79	Protein kinase N2 OS=Colobus angolensis palliatus ...	[more]
A0A4W6FI09	0.000e+0	41.62	Uncharacterized protein OS=Lates calcarifer OX=818...	[more]
A0A3S2LTY6	0.000e+0	42.44	Uncharacterized protein OS=Oryzias javanicus OX=12...	[more]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zgc:153916	0.000e+0	41.03	serine/threonine-protein kinase N2 [Source:NCBI ge...	[more]
pkn2	0.000e+0	41.25	serine/threonine-protein kinase N2 [Source:NCBI ge...	[more]
zgc:153916	0.000e+0	41.38	serine/threonine-protein kinase N2 [Source:NCBI ge...	[more]
pkn3	0.000e+0	39.79	protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131...	[more]
pkn2	0.000e+0	40.84	serine/threonine-protein kinase N2 [Source:NCBI ge...	[more]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000008480.1	9.707e-83	45.34	pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1...	[more]
PRKCD	5.669e-79	47.47	protein kinase C delta [Source:HGNC Symbol;Acc:HGN...	[more]
PRKCD	2.000e-73	47.54	protein kinase C delta [Source:HGNC Symbol;Acc:HGN...	[more]
ENSPMAT00000006766.1	6.109e-71	43.67	pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 g...	[more]
ENSPMAT00000001814.1	5.091e-60	39.84	pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gen...	[more]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
PKC1	5.087e-94	42.39	Protein serine/threonine kinase; essential for cel...	[more]
YPK1	1.381e-64	39.81	S/T protein kinase; phosphorylates, downregulates ...	[more]
YPK2	9.061e-62	38.96	Protein kinase similar to S/T protein kinase Ypk1p...	[more]
TPK3	1.377e-61	38.06	cAMP-dependent protein kinase catalytic subunit; p...	[more]
TPK1	3.647e-61	35.76	cAMP-dependent protein kinase catalytic subunit; p...	[more]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO43312	0.000e+0	41.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35585	4.239e-87	46.67	Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7S...	[more]
EDO41166	8.134e-75	40.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44938	1.405e-73	41.23	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37800	3.113e-72	42.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pkn2	0.000e+0	41.45	protein kinase N2 [Source:NCBI gene;Acc:101158798]	[more]
ENSORLT00000020420.2	0.000e+0	40.69	serine/threonine-protein kinase N1 [Source:NCBI ge...	[more]
ENSORLT00000032181.1	0.000e+0	40.57	serine/threonine-protein kinase N1 [Source:NCBI ge...	[more]
ENSORLT00000033811.1	0.000e+0	40.69	serine/threonine-protein kinase N1 [Source:NCBI ge...	[more]
pkn1a	2.168e-178	41.18	protein kinase N1 [Source:NCBI gene;Acc:101164700]	[more]

BLAST of Protein kinase N2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000065035.1	0.000e+0	100.00	SMESG000065035.1	[more]
SMESG000065035.1	0.000e+0	98.55	SMESG000065035.1	[more]
SMESG000065035.1	0.000e+0	98.31	SMESG000065035.1	[more]
SMESG000039865.1	5.268e-87	41.71	SMESG000039865.1	[more]
SMESG000014536.1	2.301e-85	46.01	SMESG000014536.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30016165 ID=SMED30016165|Name=Protein kinase N2|organism=Schmidtea mediterranea sexual|type=transcript|length=3596bp
GTTTTATATAAAATTGAATGGCAACTTTAGTGGAAATAAGAGAAAAATAC
AACATTCAATCACATAAATCCCCTGAAGAAATTATTGAAATCTTAGAAAA
TTTGCAAAATGAGAACAGAACTAAATTAAATGTTTGTTATAAAAATAAAG
CTGGCATTCAAAAAATGCTTGTGCCTGAAAATAATTCCTCGGCAGTTCTC
GTTGATGAAAAGAGGAGCTTAAATATGATTAAAAGTTTGAATATAGAAAT
TACTGATTATAAAATAAAAATTGACGATCTTGATGATGACATCCTTATTC
TCAAACAATTTGAAGATGTTCAAATTCAAGATCCAGATGATTTAAAAAGT
GAAACGTCATTAAAAAATCTTGAACATCGTTTAGCAATTGAAATCTCTGT
ACGCAATGGTGCTGAAAAACTTTTACAACTCCATAAAGGCAAACTCAAAG
ATGAAACTAGGCGATTGTATGAAGAATCAAAGATTAAAATACAGTTTATT
GAAAACCAAATCAATAGACACAAGCATCCTAATAAAGATGCCGTTGAAAA
TGACGATGATGAAATTGATGCTGTACGCACAATGAATAAATGCGATCTTG
AAATGGAAATTATCAATTTAAAGAATCGCTGCATCATTGAAAGAGCGATT
ATGCTTGGCTGTTTAAGAGGGATAAAAGCGACCAATGATAGAAATCTAAA
ACGAGATCTATTGTCAAATTATCGAGAATCTTATCAAAAAATATTTTTAT
ATCAGAAATCAATTCAGAAAGCAATTCAAAAGTTACCCAGTAATTCACAA
ATTTTCGGTGATGATAGTCTAAGTGACCTAATGAAACCGATTGAAGAACA
AATAAAATTTTCCCAAAGTCGTTTAGTGTCTCATCCAATAGCAAATAAAC
AAAGCAATTTGACCAATCTAAGTTCAATATCAGGAACTCTTGCCATAGGC
TGTTTGGGGTGCAAAGATTTGAATGATTCTTTTCCTACGAATTTGCTCTT
AGCAGGGACCGATTTAGGATTTAGTTCAACATCTACAATTATATTTCAAA
ATGCACTACAAAGTAAAACTAAACGCCCAGGATCTACTTTTCATGATGTT
CAGATTGAAGCTAAATGTGTACTGAAAATTGACAACAAACCAGTATTTGA
AACCCAATATCGTTTGATTAGTGATAACTGTTGGTTGGATTATACTGAAT
TGAAAATTGAAAGAGCAAAAGAATTAGAGGTGCAAATTTATTGTCGAAAA
ATAATTACAGACAGATCTGGAAGTAGCTGCAATGGATGGGTTCTTACAGC
ATTTAGTTTTCTAACATTGGAGGATTTTTTGGATGGTGGTAGAAATAAGT
TCCCCCTTTCTCTCTATCCCGAAGGTACAATATTTATTGACGTGACGTTT
AGTAATCCGGTTTTCGGTAATAAATTGAAACGACAAAAGCGGTTATTCTC
AAAACGAAAGGGTCAAAATATTATGAGACCGGAAGAAATGAATATGGATG
TACCATTATGGAACAGAATTATTAGTAGTGGAAATGCTACTGTCCTGCGA
AAATATACCACTATCAGCCCTCCAACGATGCCGGCACCAAATAGCGATTT
TTCTGCTGGGTACTCTATGACATGCCCTCGACCAAGTAAAAAACCAGATA
TTGATCATAACAAAGTCGTTACTGATTTGAATGCACTGGCAATAGCTGAT
ACTCAAAAACCACATTATGAGAAAAAGAAACAACATGCCTCAATGGAAGA
TCTGACAAATCTTCAAGAAAGACCACAATTTCAACATTCCACTCAAAAAA
GTGAGTATGCTGTTATGCAACCAATAAAACCCACACCGCAAAAAAGAACT
ACAAAAAAACTTGATTGGAATAACTTCCGTTGTATTTCTGTTTTGGGAAG
AGGTCATTTCGGCAAGGTTCTTTTAGCACAATATAAAAGCAACGGAAAAT
ATTACGCTATTAAAGCTTTAAAGAAAGCAGAAATACTAGCCCGTAATGAA
TTAGAAACGTTGACATCGGAAAAACGGATATTTCAAACTATTACAGAATC
TAAGCATCCTTTCCTTGTTAATTTGTTATCTTGCTTTCAATCTACGGAGC
ATGTCCTTTTTGTGATGGAATATGCAAGAGGAGGTGATCTGATGATGCAT
ATTCAAACAGATATCTTTGAGGAACCGAGAGCGGTATTTTACGCTGGTTG
CATTGTTCTTGGAATAGATTTCCTTCATTCTAAAAAGATTGTCTATCGAG
ATTTGAAACTTGATAATCTTCTTCTGGATGAGCAAGGTTATGTGAAAATG
GCAGATTTTGGATTATGTAAAGAAAATATGGGTCATGGTGATCGAACTTC
GACTTTCTGTGGAACGCCGGAATTTCTAGCTCCAGAGGTGCTTGTCGAGC
GGGACTACACACGATCTGTCGACTGGTGGGGCTTAGGAGTTCTAATATAT
GAGATGTTGGTTGGAGAGTGTCCGTTCCCGGGTGACAATGAAGAGGAGAT
ATTCGATTCAATTGTCAATCACGAAATTCGATATCCACGACATTTGTCCA
TGGAGGCAACACTGATCATGAGACGCCTTATGAGACGGACCCCAGAAAAC
CGGCTCGGTGCCAGCGCCCGCGATGCCGAGGATGTCAAGAAGCAGCCATT
TTTCCGTTCCCTGAATTTCGATGATTTATTGGCTAAGCGAGTTAAGCCGA
CTTTTGTTCCTAAACTGGCAAATGAAGAAGACGTTTCGAATTTCGATTCT
GAATTTACCCAGGAACGGCCTATATTAACACCAGCAAAAGATAGAGCATT
ACTTACAGAAAGTGACCAAAAAGCTTTTGTGGATTTTGATTTTTCTGCCG
ATTTTAGTGATTAAACATTTTGAAATAAAAAAAATAATAAACTGTTTTGT
GAATTGAAAATAAAAATAATCAAAAACTATAGCTGAATTCTGGTATTGAT
AAATCCTGGGAGCTCTGTAATAATAATTAGTTTTTTGTTAATTATTTCGA
TTAAAAACTTCATGTGCTTTAAGTGATGACATCTATATAATTATTATAAT
TATCATTATTATTATTATTACTTTATATATCCAAATGCTGTTGTGCTATT
GTTGTAATGGGAACATCACCGACAGTTGCATGATATATTTGTACAGCGAT
AGATATACATATTTGCACATTCCTGATATCTTTGAATCAATGCTACTATT
TTTTTGTTTTAATTTTTCGAGTTTGTATGTGTGTTCGTGTTAGGGCGTGT
GAGACTGTTTTGGAATATATATCAGTTTATTAGAGACATATCGGTGCTAT
TTTCTCTGGTAATGGCTCAAATGGCTGAGTGGAAATTATTTTTGCTCCAT
CTCTCTACAGCATGGAGATCTTTAATAATGATGATAACATAATAATCGTG
GATCATTTTAAATAAAGATTTTTTAATTTTCAGCTTGAAAATAGTTACTT
TTATCATTTTGTTGGTTATTGATTTATTTTTTCCTATTAGATTTTCTGAT
TTCCCTACCGATTATTTTGGGTTTGTTTTCCTTAATTTTAGCATGCAAGA
AATTTTGTAATAATCTGATGATATCTTTTGAAAAATATTTTACAGT

protein sequence of SMED30016165-orf-1

>SMED30016165-orf-1 ID=SMED30016165-orf-1|Name=SMED30016165-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=949bp
MATLVEIREKYNIQSHKSPEEIIEILENLQNENRTKLNVCYKNKAGIQKM
LVPENNSSAVLVDEKRSLNMIKSLNIEITDYKIKIDDLDDDILILKQFED
VQIQDPDDLKSETSLKNLEHRLAIEISVRNGAEKLLQLHKGKLKDETRRL
YEESKIKIQFIENQINRHKHPNKDAVENDDDEIDAVRTMNKCDLEMEIIN
LKNRCIIERAIMLGCLRGIKATNDRNLKRDLLSNYRESYQKIFLYQKSIQ
KAIQKLPSNSQIFGDDSLSDLMKPIEEQIKFSQSRLVSHPIANKQSNLTN
LSSISGTLAIGCLGCKDLNDSFPTNLLLAGTDLGFSSTSTIIFQNALQSK
TKRPGSTFHDVQIEAKCVLKIDNKPVFETQYRLISDNCWLDYTELKIERA
KELEVQIYCRKIITDRSGSSCNGWVLTAFSFLTLEDFLDGGRNKFPLSLY
PEGTIFIDVTFSNPVFGNKLKRQKRLFSKRKGQNIMRPEEMNMDVPLWNR
IISSGNATVLRKYTTISPPTMPAPNSDFSAGYSMTCPRPSKKPDIDHNKV
VTDLNALAIADTQKPHYEKKKQHASMEDLTNLQERPQFQHSTQKSEYAVM
QPIKPTPQKRTTKKLDWNNFRCISVLGRGHFGKVLLAQYKSNGKYYAIKA
LKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVM
EYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDN
LLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRS
VDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLI
MRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKL
ANEEDVSNFDSEFTQERPILTPAKDRALLTESDQKAFVDFDFSADFSD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0017049	GTP-Rho binding
GO:0004674	protein serine/threonine kinase activity
GO:0005524	ATP binding
GO:0004672	protein kinase activity
GO:0000166	nucleotide binding
GO:0003723	RNA binding
GO:0004697	protein kinase C activity
GO:0005515	protein binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0042826	histone deacetylase binding
GO:0045296	cadherin binding
GO:0070063	RNA polymerase binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000429	neoblast

Vocabulary: **INTERPRO**
Term	Definition
IPR036274	HR1_rpt_sf
IPR000961	AGC-kinase_C
IPR011072	HR1_rho-bd
IPR000719	Prot_kinase_dom
IPR017892	Pkinase_C
IPR017441	Protein_kinase_ATP_BS
IPR008271	Ser/Thr_kinase_AS
IPR011009	Kinase-like_dom_sf

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0007165	signal transduction
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0007049	cell cycle
GO:0007155	cell adhesion
GO:0010631	epithelial cell migration
GO:0016310	phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0032467	positive regulation of cytokinesis
GO:0035556	intracellular signal transduction
GO:0043297	apical junction assembly
GO:0045070	positive regulation of viral genome replication
GO:0045931	positive regulation of mitotic cell cycle
GO:0051301	cell division
GO:2000145	regulation of cell motility

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0016020	membrane
GO:0030027	lamellipodium
GO:0030054	cell junction
GO:0030496	midbody
GO:0032154	cleavage furrow
GO:0042995	cell projection
GO:0043234	protein complex
GO:0043296	apical junction complex
GO:0048471	perinuclear region of cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 143..163
None	No IPR available	COILS	Coil	Coil	coord: 647..667
None	No IPR available	COILS	Coil	Coil	coord: 70..90
None	No IPR available	GENE3D	G3DSA:1.10.287.160		coord: 107..175 e-value: 3.0E-10 score: 41.7
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 706..898 e-value: 2.0E-124 score: 416.8
None	No IPR available	GENE3D	G3DSA:3.30.200.20		coord: 617..919 e-value: 2.0E-124 score: 416.8
None	No IPR available	PANTHER	PTHR24356	SERINE/THREONINE-PROTEIN KINASE	coord: 593..945
None	No IPR available	PANTHER	PTHR24356:SF210	SERINE/THREONINE-PROTEIN KINASE N	coord: 46..511
None	No IPR available	PANTHER	PTHR24356	SERINE/THREONINE-PROTEIN KINASE	coord: 46..511
None	No IPR available	PANTHER	PTHR24356:SF210	SERINE/THREONINE-PROTEIN KINASE N	coord: 593..945
None	No IPR available	CDD	cd05589	STKc_PKN	coord: 619..944 e-value: 0.0 score: 643.969
IPR000719	Protein kinase domain	SMART	SM00220	serkin_6	coord: 619..878 e-value: 2.1E-90 score: 316.3
IPR000719	Protein kinase domain	PFAM	PF00069	Pkinase	coord: 622..878 e-value: 1.1E-62 score: 211.9
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 619..878 score: 48.527
IPR000961	AGC-kinase, C-terminal	SMART	SM00133	pkinase_C_6	coord: 879..943 e-value: 1.2E-15 score: 67.9
IPR000961	AGC-kinase, C-terminal	PROSITE	PS51285	AGC_KINASE_CTER	coord: 879..947 score: 15.055
IPR011072	HR1 rho-binding domain	SMART	SM00742	hr1_7	coord: 112..174 e-value: 0.027 score: 23.6 coord: 195..258 e-value: 0.96 score: 8.6
IPR017892	Protein kinase, C-terminal	PFAM	PF00433	Pkinase_C	coord: 900..941 e-value: 1.4E-9 score: 38.5
IPR008271	Serine/threonine-protein kinase, active site	PROSITE	PS00108	PROTEIN_KINASE_ST	coord: 740..752
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 625..648
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 597..921
IPR036274	HR1 repeat superfamily	SUPERFAMILY	SSF46585	HR1 repeat	coord: 111..168