RUN and FYVE domain-containing protein 2-like

Overview
NameRUN and FYVE domain-containing protein 2-like
Smed IDSMED30016150
Length (bp)2285
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RUN and FYVE domain-containing protein 2-like (SMED30016150) t-SNE clustered cells

Violin plots show distribution of expression levels for RUN and FYVE domain-containing protein 2-like (SMED30016150) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RUN and FYVE domain-containing protein 2-like (SMED30016150) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RUN and FYVE domain-containing protein 2-like (SMED30016150) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016150

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30016150 Contig2383GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30016150 Contig2383GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30016150 Contig2383GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
parenchymal cellSMED30016150 dd_Smed_v4_2549_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Human
Match: RUFY2 (RUN and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19761])

HSP 1 Score: 281.182 bits (718), Expect = 2.230e-84
Identity = 198/616 (32.14%), Postives = 344/616 (55.84%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSV--TIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDET--IKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKL-ISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSK------------KRIY-DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK +K   S   TI G     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK++ +Y   +  Q   L  +Y   A+++EE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K + D         + N +    I ++LDQKNY EELN  L   +++L +  + LE+  +N K++  LA   N  + L EE ++L+ EN  +        ++ + D++ E  TY+ SRQ L+ +  E  ++L++E Q+R D +  L  +V  + +IE+ M  LEK + EKQ T++ LR+Q+E++KAIN+E+ +  +  +   + K+ ++ +LEEKT  +   + Q++QR+++    ++   D+     +  L + +       ++  +L +   DL  E +  +T +EDL ++   ++   N  ++ +SL K            K+IY +Q +AL+++   L  SKL+ + ++E   + Q   W  DKE   C  C K F++S+RKHHCR CG ++C+ CS N + L SS KP+RVCD+CH  L++  +S
Sbjct:    9 VERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWG-----PLELVEKLYPE--AEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNEED---------IGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEK--SNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSS 603
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Human
Match: RUFY2 (RUN and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19761])

HSP 1 Score: 280.796 bits (717), Expect = 5.764e-84
Identity = 198/616 (32.14%), Postives = 344/616 (55.84%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSV--TIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDET--IKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKL-ISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSK------------KRIY-DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK +K   S   TI G     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK++ +Y   +  Q   L  +Y   A+++EE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K + D         + N +    I ++LDQKNY EELN  L   +++L +  + LE+  +N K++  LA   N  + L EE ++L+ EN  +        ++ + D++ E  TY+ SRQ L+ +  E  ++L++E Q+R D +  L  +V  + +IE+ M  LEK + EKQ T++ LR+Q+E++KAIN+E+ +  +  +   + K+ ++ +LEEKT  +   + Q++QR+++    ++   D+     +  L + +       ++  +L +   DL  E +  +T +EDL ++   ++   N  ++ +SL K            K+IY +Q +AL+++   L  SKL+ + ++E   + Q   W  DKE   C  C K F++S+RKHHCR CG ++C+ CS N + L SS KP+RVCD+CH  L++  +S
Sbjct:   23 VERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWG-----PLELVEKLYPE--AEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNEED---------IGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEK--SNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSS 617
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Human
Match: RUFY2 (RUN and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19761])

HSP 1 Score: 280.796 bits (717), Expect = 8.345e-84
Identity = 198/616 (32.14%), Postives = 344/616 (55.84%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSV--TIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDET--IKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKL-ISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSK------------KRIY-DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK +K   S   TI G     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK++ +Y   +  Q   L  +Y   A+++EE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K + D         + N +    I ++LDQKNY EELN  L   +++L +  + LE+  +N K++  LA   N  + L EE ++L+ EN  +        ++ + D++ E  TY+ SRQ L+ +  E  ++L++E Q+R D +  L  +V  + +IE+ M  LEK + EKQ T++ LR+Q+E++KAIN+E+ +  +  +   + K+ ++ +LEEKT  +   + Q++QR+++    ++   D+     +  L + +       ++  +L +   DL  E +  +T +EDL ++   ++   N  ++ +SL K            K+IY +Q +AL+++   L  SKL+ + ++E   + Q   W  DKE   C  C K F++S+RKHHCR CG ++C+ CS N + L SS KP+RVCD+CH  L++  +S
Sbjct:   44 VERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWG-----PLELVEKLYPE--AEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNEED---------IGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEK--SNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSS 638
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Human
Match: RUFY1 (RUN and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19760])

HSP 1 Score: 273.092 bits (697), Expect = 2.666e-81
Identity = 197/615 (32.03%), Postives = 344/615 (55.93%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKL-------SKMNLQLNFVE------KELSLSKKRIY----DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N++H+ KL +K +L+ A+   R LD D+  + Q   V+E  +KHGLK KK       + F  L+    +C       + +I  +++ +  +K+ +GR R WL + LMQK+L +Y  ++      L  +Y P A+++EE G+ I G LVGL+V+D N L L+   +DS   +G +++S Y+K D  ++D           E I  +LDQKNY EELN  L   + +LQ   + LE+  +  +  L+  T+R  +L EE  +L+ +N  ++   +   ++ + D +VE  TY+ +RQ L+ +  ++ K+LKEE ++RL+ +K L+ ++  +T++EI M  LEK   EKQ T+++LR+Q+E++KAIN+++    +  ++  + K+  +   E KT  + + + QM++R++     +  +++    S    +E        + ++ +L E+ + L KE+ S K +++ L  +L       S + ++L  VE      +EL   K  +     +Q +AL++M   L  SKL+ + ++E+  + +   W  D E   C QC K F++SRRKHHCR CG ++C+ CSSN ++L S  KP+RVCD+CH  LL+  +S  S
Sbjct:    4 ERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCP-----EASDIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDAN-LCLKGEDLDS--QVGVIDFSLYLK-DVQDLDG------GKEHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEE---RSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS 600
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Human
Match: RUFY1 (RUN and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19760])

HSP 1 Score: 273.092 bits (697), Expect = 2.666e-81
Identity = 197/615 (32.03%), Postives = 344/615 (55.93%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKL-------SKMNLQLNFVE------KELSLSKKRIY----DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N++H+ KL +K +L+ A+   R LD D+  + Q   V+E  +KHGLK KK       + F  L+    +C       + +I  +++ +  +K+ +GR R WL + LMQK+L +Y  ++      L  +Y P A+++EE G+ I G LVGL+V+D N L L+   +DS   +G +++S Y+K D  ++D           E I  +LDQKNY EELN  L   + +LQ   + LE+  +  +  L+  T+R  +L EE  +L+ +N  ++   +   ++ + D +VE  TY+ +RQ L+ +  ++ K+LKEE ++RL+ +K L+ ++  +T++EI M  LEK   EKQ T+++LR+Q+E++KAIN+++    +  ++  + K+  +   E KT  + + + QM++R++     +  +++    S    +E        + ++ +L E+ + L KE+ S K +++ L  +L       S + ++L  VE      +EL   K  +     +Q +AL++M   L  SKL+ + ++E+  + +   W  D E   C QC K F++SRRKHHCR CG ++C+ CSSN ++L S  KP+RVCD+CH  LL+  +S  S
Sbjct:    4 ERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCP-----EASDIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDAN-LCLKGEDLDS--QVGVIDFSLYLK-DVQDLDG------GKEHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEE---RSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS 600
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Celegans
Match: eea-1 (EEA1 (Early Endosome Antigen, Rab effector) homolog [Source:UniProtKB/TrEMBL;Acc:Q5FC45])

HSP 1 Score: 88.9669 bits (219), Expect = 8.160e-18
Identity = 43/104 (41.35%), Postives = 60/104 (57.69%), Query Frame = 1 
Query: 1675 EKELSLSKKRIYDQSEALEDMAKL-LENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTC 1983
            EKE S   KR +D  +AL  M +L   N  L+ D  R     +   +W DD E   C +C K F+++ RKHHCR CG +YC+ CSS  + +AS+  P+R C+TC
Sbjct: 1103 EKERSQENKRRFD--DALSAMHELGRANQSLQIDADR-----YSSRKWLDDAEAINCTECGKVFSLTVRKHHCRVCGKIYCNPCSSKSVRIASAKNPVRACNTC 1199
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Celegans
Match: eea-1 (EEA1 (Early Endosome Antigen, Rab effector) homolog [Source:UniProtKB/TrEMBL;Acc:Q5FC45])

HSP 1 Score: 88.9669 bits (219), Expect = 8.367e-18
Identity = 43/104 (41.35%), Postives = 60/104 (57.69%), Query Frame = 1 
Query: 1675 EKELSLSKKRIYDQSEALEDMAKL-LENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTC 1983
            EKE S   KR +D  +AL  M +L   N  L+ D  R     +   +W DD E   C +C K F+++ RKHHCR CG +YC+ CSS  + +AS+  P+R C+TC
Sbjct: 1101 EKERSQENKRRFD--DALSAMHELGRANQSLQIDADR-----YSSRKWLDDAEAINCTECGKVFSLTVRKHHCRVCGKIYCNPCSSKSVRIASAKNPVRACNTC 1197
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Celegans
Match: lst-2 (Lateral signaling target protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q9TZD0])

HSP 1 Score: 81.2629 bits (199), Expect = 1.261e-15
Identity = 30/74 (40.54%), Postives = 45/74 (60.81%), Query Frame = 1 
Query: 1792 ASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLA--SSSKPMRVCDTCHNALLKSY 2007
             +F   RW  D++  QC  C+ PFN  RR+HHCR CG ++CH+CS N +S+      + +RVC+ C+   L S+
Sbjct:  556 PAFMGVRWVPDEDCEQCTACSMPFNFVRRRHHCRNCGRIFCHKCSCNTISIPEHGYDRKVRVCNLCYVHRLNSF 629
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Celegans
Match: ZK632.12 (pep chromosome:WBcel235:III:9830802:9832378:1 gene:WBGene00014019.1 transcript:ZK632.12.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK632.12)

HSP 1 Score: 64.3142 bits (155), Expect = 5.044e-11
Identity = 30/70 (42.86%), Postives = 41/70 (58.57%), Query Frame = 1 
Query: 1792 ASFQEARWTDDKEVNQCIQCAKP-FNVSRRKHHCRRCGGVYCHECSSNRMSLAS-SSKPMRVCDTCHNAL 1995
            A+   A W  D E  +C+ C K  FN+ +R+HHCR CG V C  CSS    + +   KP+RVCD C ++L
Sbjct:  142 ATAHAAVWVPDGEAVKCMVCGKTQFNLVQRRHHCRNCGRVVCGACSSRTFRIDNVHKKPVRVCDHCFDSL 211
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Celegans
Match: ZK632.12 (pep chromosome:WBcel235:III:9830792:9832430:1 gene:WBGene00014019.1 transcript:ZK632.12.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK632.12)

HSP 1 Score: 64.3142 bits (155), Expect = 5.044e-11
Identity = 30/70 (42.86%), Postives = 41/70 (58.57%), Query Frame = 1 
Query: 1792 ASFQEARWTDDKEVNQCIQCAKP-FNVSRRKHHCRRCGGVYCHECSSNRMSLAS-SSKPMRVCDTCHNAL 1995
            A+   A W  D E  +C+ C K  FN+ +R+HHCR CG V C  CSS    + +   KP+RVCD C ++L
Sbjct:  142 ATAHAAVWVPDGEAVKCMVCGKTQFNLVQRRHHCRNCGRVVCGACSSRTFRIDNVHKKPVRVCDHCFDSL 211
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Fly
Match: CG31064 (gene:FBgn0051064 transcript:FBtr0085125)

HSP 1 Score: 213.386 bits (542), Expect = 8.207e-59
Identity = 186/640 (29.06%), Postives = 309/640 (48.28%), Query Frame = 1 
Query:  226 EIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK-----QTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFH-IITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMK---RDFDEV--DSLSVSEVNNTDE-TIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLK-----GENNYLKSLYDH---KNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQR----------IKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXID------ELFEKINDL---IKEVDSLKTEKEDLSEKLSKMNLQLNFVEK-------ELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSL----ASSSKPMRVCDTCHNA 1992
            EIER N++++ KLVVK++L  +++  R LD D+  +     V+E ++ HGL+PKK L          L P   + DLL+        + +I  +++ +  +++ +GR R WL++ LMQK+L +Y   +I  +   L  YY P A+++ +  V I G LVGL+VIDCN L +++  +DS    G +++S Y++   R+ D    DS   + ++ T +  + ++LDQKNY EELN  L   + NLQ     L    A  K  LA   N  L L  E   ++     G+NN   S       K K  ++ ++  R   +                           +K L+ +V  + + ++ M  LEK + EKQ TI+SLR+Q++ +K IN+E+ +  ++ +    HK+ L+ KLE +   MA+ IDQ++++          I K  S+ L + Q+    +     + ++   +E  I       +L EKI +L   +KE+   K     L   L K+  Q +  +        +LS+SK ++ +  +      +LL  S      + E   S     W  D     C  C + FN++RRKHHCR CG ++C  CS + + L        KP+RVCD C+ A
Sbjct:  131 EIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGL----------LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCN-LCVKEEDLDS--QQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSE--------------------------LEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQDCKASLTHKTELMTKLEVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTT-QVTASEERAARAEAESRIEREWRISLQEKELKLKEKIANLQGCLKELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQLLSGSAQSLQAMPEAVGS--PGIWAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCYAA 728
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Fly
Match: CG31064 (gene:FBgn0051064 transcript:FBtr0339249)

HSP 1 Score: 213.001 bits (541), Expect = 6.336e-58
Identity = 186/640 (29.06%), Postives = 309/640 (48.28%), Query Frame = 1 
Query:  226 EIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK-----QTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFH-IITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMK---RDFDEV--DSLSVSEVNNTDE-TIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLK-----GENNYLKSLYDH---KNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQR----------IKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXID------ELFEKINDL---IKEVDSLKTEKEDLSEKLSKMNLQLNFVEK-------ELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSL----ASSSKPMRVCDTCHNA 1992
            EIER N++++ KLVVK++L  +++  R LD D+  +     V+E ++ HGL+PKK L          L P   + DLL+        + +I  +++ +  +++ +GR R WL++ LMQK+L +Y   +I  +   L  YY P A+++ +  V I G LVGL+VIDCN L +++  +DS    G +++S Y++   R+ D    DS   + ++ T +  + ++LDQKNY EELN  L   + NLQ     L    A  K  LA   N  L L  E   ++     G+NN   S       K K  ++ ++  R   +                           +K L+ +V  + + ++ M  LEK + EKQ TI+SLR+Q++ +K IN+E+ +  ++ +    HK+ L+ KLE +   MA+ IDQ++++          I K  S+ L + Q+    +     + ++   +E  I       +L EKI +L   +KE+   K     L   L K+  Q +  +        +LS+SK ++ +  +      +LL  S      + E   S     W  D     C  C + FN++RRKHHCR CG ++C  CS + + L        KP+RVCD C+ A
Sbjct:  279 EIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGL----------LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCN-LCVKEEDLDS--QQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSE--------------------------LEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQDCKASLTHKTELMTKLEVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTT-QVTASEERAARAEAESRIEREWRISLQEKELKLKEKIANLQGCLKELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQLLSGSAQSLQAMPEAVGS--PGIWAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCYAA 876
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Fly
Match: CG31064 (gene:FBgn0051064 transcript:FBtr0085124)

HSP 1 Score: 152.91 bits (385), Expect = 1.980e-38
Identity = 133/443 (30.02%), Postives = 223/443 (50.34%), Query Frame = 1 
Query:  226 EIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK-----QTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFH-IITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMK---RDFDEV--DSLSVSEVNNTDE-TIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLK-----GENNYLKSLYDH---KNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQ 1491
            EIER N++++ KLVVK++L  +++  R LD D+  +     V+E ++ HGL+PKK L          L P   + DLL+        + +I  +++ +  +++ +GR R WL++ LMQK+L +Y   +I  +   L  YY P A+++ +  V I G LVGL+VIDCN L +++  +DS    G +++S Y++   R+ D    DS   + ++ T +  + ++LDQKNY EELN  L   + NLQ     L    A  K  LA   N  L L  E   ++     G+NN   S       K K  ++ ++  R   +                           +K L+ +V  + + ++ M  LEK + EKQ TI+SLR+Q++ +K IN+E+ +  +E +     K  +V +L+ K + + NI+    Q ++K    KLI  Q
Sbjct:  131 EIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGL----------LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCN-LCVKEEDLDS--QQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSE--------------------------LEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQECEDELTQKGEMVSRLQTKASQIGNIL----QSLEKKYESKLIDQQ 530
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Fly
Match: CG31064 (gene:FBgn0051064 transcript:FBtr0339248)

HSP 1 Score: 152.14 bits (383), Expect = 8.500e-38
Identity = 133/443 (30.02%), Postives = 223/443 (50.34%), Query Frame = 1 
Query:  226 EIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK-----QTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFH-IITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMK---RDFDEV--DSLSVSEVNNTDE-TIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLK-----GENNYLKSLYDH---KNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQ 1491
            EIER N++++ KLVVK++L  +++  R LD D+  +     V+E ++ HGL+PKK L          L P   + DLL+        + +I  +++ +  +++ +GR R WL++ LMQK+L +Y   +I  +   L  YY P A+++ +  V I G LVGL+VIDCN L +++  +DS    G +++S Y++   R+ D    DS   + ++ T +  + ++LDQKNY EELN  L   + NLQ     L    A  K  LA   N  L L  E   ++     G+NN   S       K K  ++ ++  R   +                           +K L+ +V  + + ++ M  LEK + EKQ TI+SLR+Q++ +K IN+E+ +  +E +     K  +V +L+ K + + NI+    Q ++K    KLI  Q
Sbjct:  279 EIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGL----------LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCN-LCVKEEDLDS--QQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSE--------------------------LEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQECEDELTQKGEMVSRLQTKASQIGNIL----QSLEKKYESKLIDQQ 678
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Fly
Match: CG31064 (gene:FBgn0051064 transcript:FBtr0085126)

HSP 1 Score: 152.14 bits (383), Expect = 9.143e-38
Identity = 133/443 (30.02%), Postives = 223/443 (50.34%), Query Frame = 1 
Query:  226 EIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK-----QTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFH-IITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMK---RDFDEV--DSLSVSEVNNTDE-TIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLK-----GENNYLKSLYDH---KNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQ 1491
            EIER N++++ KLVVK++L  +++  R LD D+  +     V+E ++ HGL+PKK L          L P   + DLL+        + +I  +++ +  +++ +GR R WL++ LMQK+L +Y   +I  +   L  YY P A+++ +  V I G LVGL+VIDCN L +++  +DS    G +++S Y++   R+ D    DS   + ++ T +  + ++LDQKNY EELN  L   + NLQ     L    A  K  LA   N  L L  E   ++     G+NN   S       K K  ++ ++  R   +                           +K L+ +V  + + ++ M  LEK + EKQ TI+SLR+Q++ +K IN+E+ +  +E +     K  +V +L+ K + + NI+    Q ++K    KLI  Q
Sbjct:  326 EIERSNLVNICKLVVKELLEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGL----------LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCN-LCVKEEDLDS--QQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSE--------------------------LEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQECEDELTQKGEMVSRLQTKASQIGNIL----QSLEKKYESKLIDQQ 725
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Zebrafish
Match: rufy2 (RUN and FYVE domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-070424-66])

HSP 1 Score: 292.352 bits (747), Expect = 2.023e-88
Identity = 206/619 (33.28%), Postives = 341/619 (55.09%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKI-NDLIKEVD-------SLKTEKEDLSEKLSKMNLQLNFVEKEL-------SLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK KK     +  G+N     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SAV+LEE G  I G LVGL+VID N     +   D D  +G +++S Y+K D D+  S    E N     I ++LDQKNY EELN  L   +  LQ     LE+   N K++  LA   N  + L EE ++L+ EN+ +      +  + + D+  E  TY+ SRQ L+ +  E  ++LKEE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR Q++++KAIN+E+ +  +        K+ ++ +LEEKT  +   + Q++QR++    E+  ++  + + K     K ++   +  + ++   ++  DL  E D        L+ E+E +++ L+    Q+N ++KE        +L K    +Q  ALE++   L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S T+
Sbjct:   33 MERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVKK-----SFLGYNKSLWGPLEMVEKLCPE--AGEIAASVRDLPGLKTPLGRARAWLRLALMQKKLADYLRLLITRKDILSEFYESSAVMLEEEGAVIVGLLVGLNVIDANLCVKGE---DLDTQVGVIDFSMYLKNDIDDYRS---EERNGQ---IAAILDQKNYVEELNRQLNSTVQGLQGRVESLEK--TNSKLIEELAIAKNNIIKLQEENHQLRTENSVILMKAQQRLAVTEGDLSCELDTYKQSRQGLDEMYNEARRQLKEECQLRQDVENELVVQVSMKQEMEMAMKLLEKDIHEKQDTLIGLRHQLDEVKAINVEMYQKMQSSDDSMRQKNDMIARLEEKTNQITATMKQLEQRLQDAERERASAEDGVRKFKQDFTNKAESLQKQIVQREKQMTQLETDLKIERDWRQTLQNELERERETITQ-LAAEAQQINGLKKEFHRLQDENTLLKGICEEQEHALEELGCKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLPASPKPVRVCDTCHAMLLQRCSSNTT 632
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Zebrafish
Match: rufy2 (RUN and FYVE domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-070424-66])

HSP 1 Score: 292.352 bits (747), Expect = 2.023e-88
Identity = 206/619 (33.28%), Postives = 341/619 (55.09%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKI-NDLIKEVD-------SLKTEKEDLSEKLSKMNLQLNFVEKEL-------SLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK KK     +  G+N     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SAV+LEE G  I G LVGL+VID N     +   D D  +G +++S Y+K D D+  S    E N     I ++LDQKNY EELN  L   +  LQ     LE+   N K++  LA   N  + L EE ++L+ EN+ +      +  + + D+  E  TY+ SRQ L+ +  E  ++LKEE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR Q++++KAIN+E+ +  +        K+ ++ +LEEKT  +   + Q++QR++    E+  ++  + + K     K ++   +  + ++   ++  DL  E D        L+ E+E +++ L+    Q+N ++KE        +L K    +Q  ALE++   L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S T+
Sbjct:   33 MERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVKK-----SFLGYNKSLWGPLEMVEKLCPE--AGEIAASVRDLPGLKTPLGRARAWLRLALMQKKLADYLRLLITRKDILSEFYESSAVMLEEEGAVIVGLLVGLNVIDANLCVKGE---DLDTQVGVIDFSMYLKNDIDDYRS---EERNGQ---IAAILDQKNYVEELNRQLNSTVQGLQGRVESLEK--TNSKLIEELAIAKNNIIKLQEENHQLRTENSVILMKAQQRLAVTEGDLSCELDTYKQSRQGLDEMYNEARRQLKEECQLRQDVENELVVQVSMKQEMEMAMKLLEKDIHEKQDTLIGLRHQLDEVKAINVEMYQKMQSSDDSMRQKNDMIARLEEKTNQITATMKQLEQRLQDAERERASAEDGVRKFKQDFTNKAESLQKQIVQREKQMTQLETDLKIERDWRQTLQNELERERETITQ-LAAEAQQINGLKKEFHRLQDENTLLKGICEEQEHALEELGCKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLPASPKPVRVCDTCHAMLLQRCSSNTT 632
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Zebrafish
Match: rufy2 (RUN and FYVE domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-070424-66])

HSP 1 Score: 293.123 bits (749), Expect = 4.663e-88
Identity = 206/619 (33.28%), Postives = 341/619 (55.09%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKI-NDLIKEVD-------SLKTEKEDLSEKLSKMNLQLNFVEKEL-------SLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK KK     +  G+N     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SAV+LEE G  I G LVGL+VID N     +   D D  +G +++S Y+K D D+  S    E N     I ++LDQKNY EELN  L   +  LQ     LE+   N K++  LA   N  + L EE ++L+ EN+ +      +  + + D+  E  TY+ SRQ L+ +  E  ++LKEE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR Q++++KAIN+E+ +  +        K+ ++ +LEEKT  +   + Q++QR++    E+  ++  + + K     K ++   +  + ++   ++  DL  E D        L+ E+E +++ L+    Q+N ++KE        +L K    +Q  ALE++   L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S T+
Sbjct:   99 MERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVKK-----SFLGYNKSLWGPLEMVEKLCPE--AGEIAASVRDLPGLKTPLGRARAWLRLALMQKKLADYLRLLITRKDILSEFYESSAVMLEEEGAVIVGLLVGLNVIDANLCVKGE---DLDTQVGVIDFSMYLKNDIDDYRS---EERNGQ---IAAILDQKNYVEELNRQLNSTVQGLQGRVESLEK--TNSKLIEELAIAKNNIIKLQEENHQLRTENSVILMKAQQRLAVTEGDLSCELDTYKQSRQGLDEMYNEARRQLKEECQLRQDVENELVVQVSMKQEMEMAMKLLEKDIHEKQDTLIGLRHQLDEVKAINVEMYQKMQSSDDSMRQKNDMIARLEEKTNQITATMKQLEQRLQDAERERASAEDGVRKFKQDFTNKAESLQKQIVQREKQMTQLETDLKIERDWRQTLQNELERERETITQ-LAAEAQQINGLKKEFHRLQDENTLLKGICEEQEHALEELGCKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLPASPKPVRVCDTCHAMLLQRCSSNTT 698
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Zebrafish
Match: rufy2 (RUN and FYVE domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-070424-66])

HSP 1 Score: 293.123 bits (749), Expect = 4.663e-88
Identity = 206/619 (33.28%), Postives = 341/619 (55.09%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKI-NDLIKEVD-------SLKTEKEDLSEKLSKMNLQLNFVEKEL-------SLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK KK     +  G+N     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SAV+LEE G  I G LVGL+VID N     +   D D  +G +++S Y+K D D+  S    E N     I ++LDQKNY EELN  L   +  LQ     LE+   N K++  LA   N  + L EE ++L+ EN+ +      +  + + D+  E  TY+ SRQ L+ +  E  ++LKEE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR Q++++KAIN+E+ +  +        K+ ++ +LEEKT  +   + Q++QR++    E+  ++  + + K     K ++   +  + ++   ++  DL  E D        L+ E+E +++ L+    Q+N ++KE        +L K    +Q  ALE++   L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S T+
Sbjct:   99 MERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVKK-----SFLGYNKSLWGPLEMVEKLCPE--AGEIAASVRDLPGLKTPLGRARAWLRLALMQKKLADYLRLLITRKDILSEFYESSAVMLEEEGAVIVGLLVGLNVIDANLCVKGE---DLDTQVGVIDFSMYLKNDIDDYRS---EERNGQ---IAAILDQKNYVEELNRQLNSTVQGLQGRVESLEK--TNSKLIEELAIAKNNIIKLQEENHQLRTENSVILMKAQQRLAVTEGDLSCELDTYKQSRQGLDEMYNEARRQLKEECQLRQDVENELVVQVSMKQEMEMAMKLLEKDIHEKQDTLIGLRHQLDEVKAINVEMYQKMQSSDDSMRQKNDMIARLEEKTNQITATMKQLEQRLQDAERERASAEDGVRKFKQDFTNKAESLQKQIVQREKQMTQLETDLKIERDWRQTLQNELERERETITQ-LAAEAQQINGLKKEFHRLQDENTLLKGICEEQEHALEELGCKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLPASPKPVRVCDTCHAMLLQRCSSNTT 698
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Zebrafish
Match: rufy2 (RUN and FYVE domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-070424-66])

HSP 1 Score: 290.812 bits (743), Expect = 6.228e-88
Identity = 205/619 (33.12%), Postives = 340/619 (54.93%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKI-NDLIKEVD-------SLKTEKEDLSEKLSKMNLQLNFVEKEL-------SLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK KK     +  G+N     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SAV+LEE G  I G LVGL+VID N     +   D D  +G +++S Y+K D D+  S    E N     I ++LDQKNY EELN  L   +  LQ     LE+   N K++  LA   N  + L EE ++L+ EN+ +      +  + + D+  E  TY+ SRQ L+ +  E  ++LKEE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR Q++++KAIN+E+ +  +        K+ ++ +LEEKT  +   + Q++QR++    E+  ++  + + K     K ++   +  + ++   ++  DL  E D        L+ E+E +++ L+    Q+N ++KE        +  K    +Q  ALE++   L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S T+
Sbjct:   33 MERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVKK-----SFLGYNKSLWGPLEMVEKLCPE--AGEIAASVRDLPGLKTPLGRARAWLRLALMQKKLADYLRLLITRKEILSEFYESSAVMLEEEGAVIVGLLVGLNVIDANLCVKGE---DLDTQVGVIDFSMYLKNDIDDYRS---EERNG---QIAAILDQKNYVEELNRQLNSTVQGLQGRVESLEK--TNSKLIEELAIAKNNIIKLQEENHQLRTENSVILMKAQQRLAVTEGDLNCELDTYKQSRQGLDEMYNEARRQLKEECQLRQDVENELVVQVSMKQEMEMAMKLLEKDIHEKQDTLIGLRHQLDEVKAINVEMYQKMQSSDDSMRQKNDMIARLEEKTNQITATMKQLEQRLQDAERERASAEDGVRKFKQDFTNKAESLQKQIVQREKQMTQLETDLKIERDWRQTLQNELERERETITQ-LAAEAQQINGLKKEFHRLQDENTQLKGICEEQEHALEELGCKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLPASPKPVRVCDTCHAMLLQRCSSNTT 632
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Xenopus
Match: fam43b (family with sequence similarity 43 member B [Source:Xenbase;Acc:XB-GENE-6049910])

HSP 1 Score: 267.7 bits (683), Expect = 2.061e-79
Identity = 193/621 (31.08%), Postives = 339/621 (54.59%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKIND----LIKEVDSLKTEKEDLSEKLSKMN---------------LQLNF--VEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N+++  KL +K +++ A+   R +D + P + Q   V+E  +KHGLK KK   +   + +  L+    +C       S ++   I+ +  +K+ +G+ R WL + LMQK+L +Y   +      L  +Y   A+++EE G  I G LVGL++ID N L L+   +DS   +G +++S Y+K D  + D+        +DE + ++LDQK+Y EELN  L   + +LQ   + LE+   N K+   L    +R ++L EE N +  E+  ++   +   ++   D +VE  TY+ SRQ L+ +  E+ K+LK E Q RL+ +K  + +V  +T++E+ M  +EK + EKQ T++ LRKQ++ +KAIN+++ +   + +T    K+ +V+ ++ K   + + + Q+++R++K       S++    ++    + +     K   + +  EK+N     L K++ S   + + L +KL K                 LQ NF  + +E    ++   +Q +AL++M + L  SKL+ + ++E+  + +   W  D E  +C QC K F++SRRKHHCR CG ++C+ CSSN +SL S  KP+RVCD CHN LL+  +S +S
Sbjct:    3 ERANLMNRMKLSIKVLIQSALNLGRCIDSEYPPLQQFFLVMEHCLKHGLKVKKTFMAQNKSFYGPLELVEKLCP-----ESSDLFANIKNLPELKTAIGKGRAWLHLALMQKKLADYLQALIDHKDLLSDFYEQDALMMEEEGAVIVGLLVGLNMIDAN-LCLKGEDLDS--QVGVIDFSFYLK-DMQQNDN-----EKQSDEIV-AVLDQKHYVEELNRHLSCTVGDLQAKIDSLEK--TNSKLTEELLAAKDRIVSLQEEHNHILQESTLIREKSERSVEVSFQDTKVELDTYKQSRQGLDEMYNEIWKQLKVEKQARLELEKEFELQVGMKTEMEMAMKLMEKDIHEKQDTLVVLRKQLDDVKAINLQMCQKVLDAETALHKKNEIVNSVQAKGDQLTSALKQIEERLQK-------SEKTREAAEENCNKMKMEHGAKIGSLQQQLEKLNKTCAVLEKDLKSENEKHDTLQDKLHKEKETATSLRNELHQFSLLQKNFDNLHQEKKQLQRLCEEQEQALQEMGQHLSQSKLKMEDIKEVNKALKGHTWLKDDEATECKQCNKEFSISRRKHHCRNCGDIFCNSCSSNELSLPSYPKPVRVCDICHNLLLQRCSSNSS 599
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Xenopus
Match: fam43b (family with sequence similarity 43 member B [Source:Xenbase;Acc:XB-GENE-6049910])

HSP 1 Score: 267.7 bits (683), Expect = 2.666e-79
Identity = 193/621 (31.08%), Postives = 339/621 (54.59%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKIND----LIKEVDSLKTEKEDLSEKLSKMN---------------LQLNF--VEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N+++  KL +K +++ A+   R +D + P + Q   V+E  +KHGLK KK   +   + +  L+    +C       S ++   I+ +  +K+ +G+ R WL + LMQK+L +Y   +      L  +Y   A+++EE G  I G LVGL++ID N L L+   +DS   +G +++S Y+K D  + D+        +DE + ++LDQK+Y EELN  L   + +LQ   + LE+   N K+   L    +R ++L EE N +  E+  ++   +   ++   D +VE  TY+ SRQ L+ +  E+ K+LK E Q RL+ +K  + +V  +T++E+ M  +EK + EKQ T++ LRKQ++ +KAIN+++ +   + +T    K+ +V+ ++ K   + + + Q+++R++K       S++    ++    + +     K   + +  EK+N     L K++ S   + + L +KL K                 LQ NF  + +E    ++   +Q +AL++M + L  SKL+ + ++E+  + +   W  D E  +C QC K F++SRRKHHCR CG ++C+ CSSN +SL S  KP+RVCD CHN LL+  +S +S
Sbjct:   10 ERANLMNRMKLSIKVLIQSALNLGRCIDSEYPPLQQFFLVMEHCLKHGLKVKKTFMAQNKSFYGPLELVEKLCP-----ESSDLFANIKNLPELKTAIGKGRAWLHLALMQKKLADYLQALIDHKDLLSDFYEQDALMMEEEGAVIVGLLVGLNMIDAN-LCLKGEDLDS--QVGVIDFSFYLK-DMQQNDN-----EKQSDEIV-AVLDQKHYVEELNRHLSCTVGDLQAKIDSLEK--TNSKLTEELLAAKDRIVSLQEEHNHILQESTLIREKSERSVEVSFQDTKVELDTYKQSRQGLDEMYNEIWKQLKVEKQARLELEKEFELQVGMKTEMEMAMKLMEKDIHEKQDTLVVLRKQLDDVKAINLQMCQKVLDAETALHKKNEIVNSVQAKGDQLTSALKQIEERLQK-------SEKTREAAEENCNKMKMEHGAKIGSLQQQLEKLNKTCAVLEKDLKSENEKHDTLQDKLHKEKETATSLRNELHQFSLLQKNFDNLHQEKKQLQRLCEEQEQALQEMGQHLSQSKLKMEDIKEVNKALKGHTWLKDDEATECKQCNKEFSISRRKHHCRNCGDIFCNSCSSNELSLPSYPKPVRVCDICHNLLLQRCSSNSS 606
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Xenopus
Match: fam43b (family with sequence similarity 43 member B [Source:Xenbase;Acc:XB-GENE-6049910])

HSP 1 Score: 236.113 bits (601), Expect = 4.381e-68
Identity = 186/602 (30.90%), Postives = 304/602 (50.50%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNF--VEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N+++  KL +K +++ A+   R +D + P + Q   V+E  +KHGLK KK   +   + +  L+    +C       S ++   I+ +  +K+ +G+ R WL + LMQK+L +Y   +      L  +Y   A+++EE G  I G LVGL++ID N   L  ++  SD                                 I ++LDQK+Y EELN  L   + +LQ   + LE+   N K+   L    +R ++L EE N +  E+  ++   +   ++   D +VE  TY+ SRQ L+ +  E+ K+LK E Q RL+ +K  + +V  +T++E+ M  +EK + EKQ T++ LRKQ++ +KAIN+++             + VLV K     A   +  D +D+    FV  K                 EK    + E+ D L +K++   +   SL+ E    S       LQ NF  + +E    ++   +Q +AL++M + L  SKL+ + ++E+  + +   W  D E  +C QC K F++SRRKHHCR CG ++C+ CSSN +SL S  KP+RVCD CHN LL+  +S +S
Sbjct:   22 ERANLMNRMKLSIKVLIQSALNLGRCIDSEYPPLQQFFLVMEHCLKHGLKVKKTFMAQNKSFYGPLELVEKLCP-----ESSDLFANIKNLPELKTAIGKGRAWLHLALMQKKLADYLQALIDHKDLLSDFYEQDALMMEEEGAVIVGLLVGLNMIDANLSFLCCSSCRSD--------------------------------EIVAVLDQKHYVEELNRHLSCTVGDLQAKIDSLEK--TNSKLTEELLAAKDRIVSLQEEHNHILQESTLIREKSERSVEVSFQDTKVELDTYKQSRQGLDEMYNEIWKQLKVEKQARLELEKEFELQVGMKTEMEMAMKLMEKDIHEKQDTLVVLRKQLDDVKAINLQMC------------QKVLVRKCNITFA--VHEFDSLDRITGIFVFLKAF-------FCFNSAVLEKDLKSENEKHDTLQDKLHKEKETATSLRNELHQFSL------LQKNFDNLHQEKKQLQRLCEEQEQALQEMGQHLSQSKLKMEDIKEVNKALKGHTWLKDDEATECKQCNKEFSISRRKHHCRNCGDIFCNSCSSNELSLPSYPKPVRVCDICHNLLLQRCSSNSS 557
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Xenopus
Match: rufy3 (RUN and FYVE domain containing 3 [Source:NCBI gene;Acc:779660])

HSP 1 Score: 194.897 bits (494), Expect = 4.142e-53
Identity = 144/433 (33.26%), Postives = 240/433 (55.43%), Query Frame = 1 
Query:  193 TKENNEILSDFEIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK--QTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEK 1476
            T++ N ++++   ER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G N     P+  +L++K    + EI  +++ + G+++ +GR R WL++ LMQK+L  Y   + ++   L  +Y P+A+++EE G  I+G LVGL+VID NF  ++   +DS   +G +++S Y+K          +++ +  D  I ++LDQKNY EELN  L   + NLQ   + LE+  +N K+   LA   NR + + EE+ ++K E +Y    Y   NK                R        E++K LKEE Q+RLD +K L+ ++  R ++E+ M  L+K V EKQ  + +LR+Q++ L+A+  EL+   +      + KS L  +LEEKT  MA  + Q++QR++  VSE+
Sbjct:   76 TEDPNYLMAN---ERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK-----TFLGQNKSFWGPL--ELVEKLVPEAAEITASVKDLPGLRTPVGRGRAWLRLALMQKKLSEYMKALINRKDLLSEFYEPNALMMEEEGAIISGLLVGLNVIDANFC-MKGEDLDS--QVGVIDFSMYLKEG-------PIAKCSEGDGQITAILDQKNYVEELNRQLSATVNNLQAKVDALEK--SNTKLTEELAVANNRIITMQEEMERIKEETSY----YSEVNK--------------QERTADGQALSEVKKHLKEETQLRLDIEKELEVQIGMRQEMELAMKMLDKDVCEKQDALAALRQQLDDLRALKHELSFKLQSSDLALKQKSELNSRLEEKTNQMAATVKQLEQRLR--VSER 466

HSP 2 Score: 62.3882 bits (150), Expect = 1.885e-9
Identity = 24/61 (39.34%), Postives = 35/61 (57.38%), Query Frame = 1 
Query: 1840 CIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            C  C   F+    K+ C+ CGG++C  CS+N + L SS  P RVC+ CH  L++ Y+   S
Sbjct:  504 CQLCQSEFSNLLSKNVCKNCGGIFCPSCSANELPLPSSINPERVCNPCHKKLIEQYSYSPS 564
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Xenopus
Match: rufy3 (RUN and FYVE domain containing 3 [Source:NCBI gene;Acc:779660])

HSP 1 Score: 194.897 bits (494), Expect = 4.534e-53
Identity = 141/420 (33.57%), Postives = 231/420 (55.00%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK--QTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEK 1476
            ER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G N     P+  +L++K    + EI  +++ + G+++ +GR R WL++ LMQK+L  Y   + ++   L  +Y P+A+++EE G  I+G LVGL+VID NF  ++   +DS   +G +++S Y+K          +++ +  D  I ++LDQKNY EELN  L   + NLQ   + LE+  +N K+   LA   NR + + EE+ ++K E +Y        NK                R        E++K LKEE Q+RLD +K L+ ++  R ++E+ M  L+K V EKQ  + +LR+Q++ L+A+  EL+   +      + KS L  +LEEKT  MA  + Q++QR++  VSE+
Sbjct:   68 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK-----TFLGQNKSFWGPL--ELVEKLVPEAAEITASVKDLPGLRTPVGRGRAWLRLALMQKKLSEYMKALINRKDLLSEFYEPNALMMEEEGAIISGLLVGLNVIDANFC-MKGEDLDS--QVGVIDFSMYLKEG-------PIAKCSEGDGQITAILDQKNYVEELNRQLSATVNNLQAKVDALEK--SNTKLTEELAVANNRIITMQEEMERIKEETSYYSEASKKVNK--------------QERTADGQALSEVKKHLKEETQLRLDIEKELEVQIGMRQEMELAMKMLDKDVCEKQDALAALRQQLDDLRALKHELSFKLQSSDLALKQKSELNSRLEEKTNQMAATVKQLEQRLR--VSER 452
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Mouse
Match: Rufy2 (RUN and FYVE domain-containing 2 [Source:MGI Symbol;Acc:MGI:1917682])

HSP 1 Score: 279.256 bits (713), Expect = 7.983e-84
Identity = 199/618 (32.20%), Postives = 344/618 (55.66%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSV--TIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDET--IKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIK---KFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSK------------KRIY-DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK +K   S   TI G     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK++ +Y   +  Q   L  +Y   A+++EE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K +          E+ N +    I ++LDQKNY EELN  L   +++L +  + LE+  +N K++  LA   N  + L EE ++L+ EN  +        ++ + D++ E  TY+ SRQ L+ +  +  ++L++E Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR+Q+E++KAIN+E+ +  +  +   + K+ ++ +LEEKT  +   + Q++QR++   K   E    D+   +      +  +    ++E+  +L +   DL  E +  +T +EDL ++   ++   +  +K +SL K            KRIY +Q +AL+++   L  SKL+ D ++E   + Q   W  DK+   C  C K F++S+RKHHCR CG ++C+ CS N + L SS KP+RVCD+CH  L++  +S
Sbjct:    9 VERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKGRKSFLSYNKTIWG-----PLELVEKLYPE--AEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRELLSEFYEYHALMMEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNE---------EEIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEK--SNTKLIEELAIAKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVDVETELQTYKHSRQGLDEMYNDARRQLRDESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQRLQGSEDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQKEAEAEDEKYAQECLSQSDSLQRQISQKEQ--QLVQLETDLKIEKEWRQTLQEDLQKEKDVLSHLRHETQKVISLKKEFLNLQDENQQLKRIYQEQEQALQELGSKLCESKLKIDDIKEANKALQGLVWLKDKDATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHAMLIQRCSS 603
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Mouse
Match: Rufy1 (RUN and FYVE domain containing 1 [Source:MGI Symbol;Acc:MGI:2429762])

HSP 1 Score: 280.026 bits (715), Expect = 5.808e-83
Identity = 196/615 (31.87%), Postives = 346/615 (56.26%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSK-------MNLQLNFVE---KEL-------SLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N++H+ KL +K +L+ A+   R LD D   + Q   V+E  +KHGLK KK       + F  L+    +C       + +I  +++ +  +K+ +GR R WL + LMQK+L +Y  ++    + L  +Y P A+++EE G+ I G LVGL+V+D N L L+   +DS   +G +++S  +K D  ++DS          E I  +LDQKNY EELN  L   + +LQ   + LE+  +  +  L+  T+R  +L +E  +L+ +N  ++   +   ++ + D +VE  TY+ +RQ L+ +  ++ K+LKEE ++RL+ +K L+ ++  +T++EI M  LEK   EKQ T+++LR+Q+E++KAIN+++    +  ++  + K+  +   E KT  + + + QM++R+++    +  +++    S    +E     S  + ++ +L ++ + L KE+ S K +++ L  +L +       +  +L  VE   KEL       +  +K   +Q +AL++M   L  SKL+ + ++E+  + +   W  D E   C QC K F++SRRKHHCR CG ++C+ CSSN ++L S  KP+RVCD+CH  LL+  +S  S
Sbjct:  116 ERANLMHMMKLSIKVLLQSALSLGRSLDADYAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCP-----EASDIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKQLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDAN-LCLKGEDLDS--QVGVIDFSLCLK-DAQDLDS------GREHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQKEQQQLREQNEVIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKVQSAESSLQQKNEAIASFEGKTTQVMSSMKQMEERLQQAERARQAAEE---RSHKLQQELSGRGSALQLQLSQLRDQCSGLEKELKSEKEQRQALQRELQREKDTSCLLQTELQQVEGLKKELRELQDEKAELRKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKDFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS 712
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Mouse
Match: Rufy3 (RUN and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:106484])

HSP 1 Score: 231.876 bits (590), Expect = 1.176e-65
Identity = 191/620 (30.81%), Postives = 314/620 (50.65%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQL----------------NFVEKELSL-SKKRIYDQS----EALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            ER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G N     P  ++  L+ +  + EI  +++ + G+K+ +GR R WL++ LMQK+L  Y   + ++   L  +Y  +A+++EE G  IAG LVGL+VID NF  ++   +DS + +  +++S Y+K         + S+ +  D  I ++LDQKNY EELN  L   + NLQ   +LLE+  +N K+   LA   NR + L EE+ ++K E++YL              ++  R   +  R        E  K LKEE Q+RLD +K L+ ++  R ++E+ M  LEK V EKQ  ++SLR+Q++ L+A+  EL    +      + KS L  +LEEKT  MA  I Q++QR+++    +  ++                        + LF++  D   +++SL+ E E L+ + +++ L+L                   + EL +  K RI +++    + LE+  +LL +   E     + Q S  E           C  C +  + S  K+ CR C G +C+ C++N + L SS KP RVC+ CH  L+K Y+S
Sbjct:  118 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK-----TFLGQNKSFWGPLELVEKLVPE--AAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEVNALMMEEEGAIIAGLLVGLNVIDANFC-MKGEDLDSQVGV--IDFSMYLKDG-------NSSKGSEGDGQITAILDQKNYVEELNRHLNATVNNLQTKVDLLEK--SNTKLTEELAVANNRIITLQEEMERVKEESSYL--------------LESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERGRQSAE----------------------LDNRLFKQ--DFGDKINSLQLEVEALTRQRTQLELELKQEKERKSQNRGTPGKGAQKPELRMDGKHRIQEENVKLKKPLEESHRLLTHPAEE-----QGQPSLSEKPQV-------CQLCQE--DDSLTKNTCRNCRGTFCNACTTNELPLPSSIKPERVCNPCHEQLIKQYSS 666
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Mouse
Match: Rufy3 (RUN and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:106484])

HSP 1 Score: 195.667 bits (496), Expect = 2.104e-54
Identity = 145/419 (34.61%), Postives = 228/419 (54.42%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSE 1473
            ER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G N     P  ++  L+ +  + EI  +++ + G+K+ +GR R WL++ LMQK+L  Y   + ++   L  +Y  +A+++EE G  IAG LVGL+VID NF  ++   +DS   +G +++S Y+K         + S+ +  D  I ++LDQKNY EELN  L   + NLQ   +LLE+  +N K+   LA   NR + L EE+ ++K E++YL              ++  R   +  R        E  K LKEE Q+RLD +K L+ ++  R ++E+ M  LEK V EKQ  ++SLR+Q++ L+A+  EL    +      + KS L  +LEEKT  MA  I Q++Q  K  V +
Sbjct:   68 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK-----TFLGQNKSFWGPLELVEKLVPE--AAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEVNALMMEEEGAIIAGLLVGLNVIDANFC-MKGEDLDS--QVGVIDFSMYLKDG-------NSSKGSEGDGQITAILDQKNYVEELNRHLNATVNNLQTKVDLLEK--SNTKLTEELAVANNRIITLQEEMERVKEESSYL--------------LESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQ 453
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Mouse
Match: Rufy3 (RUN and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:106484])

HSP 1 Score: 196.052 bits (497), Expect = 2.307e-54
Identity = 145/419 (34.61%), Postives = 228/419 (54.42%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNN--LDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSE 1473
            ER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G N     P  ++  L+ +  + EI  +++ + G+K+ +GR R WL++ LMQK+L  Y   + ++   L  +Y  +A+++EE G  IAG LVGL+VID NF  ++   +DS   +G +++S Y+K         + S+ +  D  I ++LDQKNY EELN  L   + NLQ   +LLE+  +N K+   LA   NR + L EE+ ++K E++YL              ++  R   +  R        E  K LKEE Q+RLD +K L+ ++  R ++E+ M  LEK V EKQ  ++SLR+Q++ L+A+  EL    +      + KS L  +LEEKT  MA  I Q++Q  K  V +
Sbjct:   86 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK-----TFLGQNKSFWGPLELVEKLVPE--AAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEVNALMMEEEGAIIAGLLVGLNVIDANFC-MKGEDLDS--QVGVIDFSMYLKDG-------NSSKGSEGDGQITAILDQKNYVEELNRHLNATVNNLQTKVDLLEK--SNTKLTEELAVANNRIITLQEEMERVKEESSYL--------------LESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQ 471
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. UniProt/SwissProt
Match: sp|Q8WXA3|RUFY2_HUMAN (RUN and FYVE domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RUFY2 PE=1 SV=3)

HSP 1 Score: 281.182 bits (718), Expect = 1.071e-83
Identity = 198/616 (32.14%), Postives = 344/616 (55.84%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSV--TIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDET--IKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKL-ISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSK------------KRIY-DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK +K   S   TI G     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK++ +Y   +  Q   L  +Y   A+++EE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K + D         + N +    I ++LDQKNY EELN  L   +++L +  + LE+  +N K++  LA   N  + L EE ++L+ EN  +        ++ + D++ E  TY+ SRQ L+ +  E  ++L++E Q+R D +  L  +V  + +IE+ M  LEK + EKQ T++ LR+Q+E++KAIN+E+ +  +  +   + K+ ++ +LEEKT  +   + Q++QR+++    ++   D+     +  L + +       ++  +L +   DL  E +  +T +EDL ++   ++   N  ++ +SL K            K+IY +Q +AL+++   L  SKL+ + ++E   + Q   W  DKE   C  C K F++S+RKHHCR CG ++C+ CS N + L SS KP+RVCD+CH  L++  +S
Sbjct:    9 VERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWG-----PLELVEKLYPE--AEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNEED---------IGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEK--SNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSS 603
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. UniProt/SwissProt
Match: sp|Q5R5R4|RUFY2_PONAB (RUN and FYVE domain-containing protein 2 OS=Pongo abelii OX=9601 GN=RUFY2 PE=2 SV=1)

HSP 1 Score: 280.796 bits (717), Expect = 1.657e-83
Identity = 198/616 (32.14%), Postives = 344/616 (55.84%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSV--TIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDET--IKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKL-ISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSK------------KRIY-DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK +K   S   TI G     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK++ +Y   +  Q   L  +Y   A+++EE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K + D         + N +    I ++LDQKNY EELN  L   +++L +  + LE+  +N K++  LA   N  + L EE ++L+ EN  +        ++ + D++ E  TY+ SRQ L+ +  E  ++L++E Q+R D +  L  +V  + +IE+ M  LEK + EKQ T++ LR+Q+E++KAIN+E+ +  +  +   + K+ ++ +LEEKT  +   + Q++QR+++    ++   D+     +  L + +       ++  +L +   DL  E +  +T +EDL ++   ++   N  ++ +SL K            K+IY +Q +AL+++   L  SKL+ + ++E   + Q   W  DKE   C  C K F++S+RKHHCR CG ++C+ CS N + L SS KP+RVCD+CH  L++  +S
Sbjct:    9 VERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVRKSFLSYNKTIWG-----PLELVEKLYPE--AEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNEED---------IGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEK--SNTKLIEELAIAKNNIIKLQEENHQLRNENKLILMKTQQHIEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSS 603
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. UniProt/SwissProt
Match: sp|Q8R4C2|RUFY2_MOUSE (RUN and FYVE domain-containing protein 2 OS=Mus musculus OX=10090 GN=Rufy2 PE=1 SV=2)

HSP 1 Score: 279.256 bits (713), Expect = 5.584e-83
Identity = 199/618 (32.20%), Postives = 344/618 (55.66%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSV--TIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDET--IKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIK---KFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSK------------KRIY-DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK +K   S   TI G     P  ++  L  +  + EI  +++ + G+K+ LGR R WL++ LMQK++ +Y   +  Q   L  +Y   A+++EE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K +          E+ N +    I ++LDQKNY EELN  L   +++L +  + LE+  +N K++  LA   N  + L EE ++L+ EN  +        ++ + D++ E  TY+ SRQ L+ +  +  ++L++E Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR+Q+E++KAIN+E+ +  +  +   + K+ ++ +LEEKT  +   + Q++QR++   K   E    D+   +      +  +    ++E+  +L +   DL  E +  +T +EDL ++   ++   +  +K +SL K            KRIY +Q +AL+++   L  SKL+ D ++E   + Q   W  DK+   C  C K F++S+RKHHCR CG ++C+ CS N + L SS KP+RVCD+CH  L++  +S
Sbjct:    9 VERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKGRKSFLSYNKTIWG-----PLELVEKLYPE--AEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRELLSEFYEYHALMMEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNE---------EEIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEK--SNTKLIEELAIAKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVDVETELQTYKHSRQGLDEMYNDARRQLRDESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQRLQGSEDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQKEAEAEDEKYAQECLSQSDSLQRQISQKEQ--QLVQLETDLKIEKEWRQTLQEDLQKEKDVLSHLRHETQKVISLKKEFLNLQDENQQLKRIYQEQEQALQELGSKLCESKLKIDDIKEANKALQGLVWLKDKDATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHAMLIQRCSS 603
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. UniProt/SwissProt
Match: sp|Q8BIJ7|RUFY1_MOUSE (RUN and FYVE domain-containing protein 1 OS=Mus musculus OX=10090 GN=Rufy1 PE=1 SV=1)

HSP 1 Score: 280.026 bits (715), Expect = 4.063e-82
Identity = 196/615 (31.87%), Postives = 346/615 (56.26%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSK-------MNLQLNFVE---KEL-------SLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N++H+ KL +K +L+ A+   R LD D   + Q   V+E  +KHGLK KK       + F  L+    +C       + +I  +++ +  +K+ +GR R WL + LMQK+L +Y  ++    + L  +Y P A+++EE G+ I G LVGL+V+D N L L+   +DS   +G +++S  +K D  ++DS          E I  +LDQKNY EELN  L   + +LQ   + LE+  +  +  L+  T+R  +L +E  +L+ +N  ++   +   ++ + D +VE  TY+ +RQ L+ +  ++ K+LKEE ++RL+ +K L+ ++  +T++EI M  LEK   EKQ T+++LR+Q+E++KAIN+++    +  ++  + K+  +   E KT  + + + QM++R+++    +  +++    S    +E     S  + ++ +L ++ + L KE+ S K +++ L  +L +       +  +L  VE   KEL       +  +K   +Q +AL++M   L  SKL+ + ++E+  + +   W  D E   C QC K F++SRRKHHCR CG ++C+ CSSN ++L S  KP+RVCD+CH  LL+  +S  S
Sbjct:  116 ERANLMHMMKLSIKVLLQSALSLGRSLDADYAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCP-----EASDIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKQLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDAN-LCLKGEDLDS--QVGVIDFSLCLK-DAQDLDS------GREHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQKEQQQLREQNEVIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKVQSAESSLQQKNEAIASFEGKTTQVMSSMKQMEERLQQAERARQAAEE---RSHKLQQELSGRGSALQLQLSQLRDQCSGLEKELKSEKEQRQALQRELQREKDTSCLLQTELQQVEGLKKELRELQDEKAELRKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKDFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS 712
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. UniProt/SwissProt
Match: sp|Q96T51|RUFY1_HUMAN (RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2)

HSP 1 Score: 271.937 bits (694), Expect = 2.852e-79
Identity = 197/615 (32.03%), Postives = 344/615 (55.93%), Query Frame = 1 
Query:  232 ERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMG-IKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKL-------SKMNLQLNFVE------KELSLSKKRIY----DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            ER N++H+ KL +K +L+ A+   R LD D+  + Q   V+E  +KHGLK KK       + F  L+    +C       + +I  +++ +  +K+ +GR R WL + LMQK+L +Y  ++      L  +Y P A+++EE G+ I G LVGL+V+D N L L+   +DS   +G +++S Y+K D  ++D           E I  +LDQKNY EELN  L   + +LQ   + LE+  +  +  L+  T+R  +L EE  +L+ +N  ++   +   ++ + D +VE  TY+ +RQ L+ +  ++ K+LKEE ++RL+ +K L+ ++  +T++EI M  LEK   EKQ T+++LR+Q+E++KAIN+++    +  ++  + K+  +   E KT  + + + QM++R++     +  +++    S    +E        + ++ +L E+ + L KE+ S K +++ L  +L       S + ++L  VE      +EL   K  +     +Q +AL++M   L  SKL+ + ++E+  + +   W  D E   C QC K F++SRRKHHCR CG ++C+ CSSN ++L S  KP+RVCD+CH  LL+  +S  S
Sbjct:  112 ERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCP-----EASDIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDAN-LCLKGEDLDS--QVGVIDFSLYLK-DVQDLDG------GKEHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEE---RSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS 708
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. TrEMBL
Match: A0A1S3I786 (RUN and FYVE domain-containing protein 2 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106161606 PE=4 SV=1)

HSP 1 Score: 336.65 bits (862), Expect = 1.810e-101
Identity = 230/618 (37.22%), Postives = 358/618 (57.93%), Query Frame = 1 
Query:  193 TKENNEILSDFEIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKK-ILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIET-IQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHI-ITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKR-------IYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            TK   E      IER N++H+ KLV+K+++  ++   R LD+D   + Q   VLE +++HGLKPKK IL        +  + +PV+  + K  +  E I T ++ M  +K+ LGR R +L++ LMQK+L +YF + I  +   L  +Y P A +LEE G+ I+G LVGL+VIDCN     D   D D  +G +++S Y+K D   +      + +  +  + ++LDQKNY EELN  L   +TNLQ     ++      +  LA   N  L L EE ++L+ E   L++ Y  K +  Q D+ VER TY TSRQ L+ L  + +K+ +EE+Q+R+D +K L+ ++  +T++E+ M  LEK V EKQ T++SLRKQ++++K IN+EL    +      +HK+ LV KLEEKT  M   +  M+ R+K+  S+K+ +++   +   +L EK+   +  E ++    E    + K   +L+ E+  +S+  S +  Q+  V++E S   KR         +Q +AL ++   L  SKL+ + LRE Q + +EA+W DD E   C  C K F++SRRKHHCR CG +YC ECS N+M L SS+KP+RVCD CH  LL+ Y++
Sbjct:   56 TKPKRERRDPMAIERSNLLHVAKLVIKELIDSSLSQGRMLDDDFVPLQQFFVVLEHVLRHGLKPKKSILR-------DKREFFPVLEQIEKHVSEAEEITTSVRDMPNLKTPLGRARAFLRLALMQKRLADYFKVLIDKKDDVLVDFYEPGAFMLEEEGIVISGLLVGLNVIDCNICIKED---DLDEPMGVIDFSLYLK-DNSFLGQNEEEDGSEGNAKMAAILDQKNYLEELNRHLNATVTNLQQKMEAVQTSNTLMREDLAISKNNILALQEENSQLRHEKEGLETSYQRKMESAQADLSVERETYITSRQGLDHLYADSKKREEEEIQMRMDLEKELELQIGMKTEMEMAMRLLEKDVHEKQDTVVSLRKQLDEIKQINLELYNKLQACDGSLKHKTELVAKLEEKTNQMQEAMRAMEARVKQCESDKIAAEETARKLGQQLAEKDSRRAALETDLRIEREWRGTVQK---TLEQERGKVSQLQSDLQ-QMGKVKQEYSDLMKRHESMKQTCEEQEKALTELGSHLSESKLKMEDLREAQQALKEAQWADDAEATNCKGCTKEFSLSRRKHHCRNCGDIYCSECSDNKMPLPSSAKPVRVCDNCHTLLLQRYSA 658
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. TrEMBL
Match: A0A1S3I7A0 (RUN and FYVE domain-containing protein 2 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106161606 PE=4 SV=1)

HSP 1 Score: 335.109 bits (858), Expect = 3.486e-101
Identity = 227/606 (37.46%), Postives = 355/606 (58.58%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKK-ILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIET-IQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHI-ITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKR-------IYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            IER N++H+ KLV+K+++  ++   R LD+D   + Q   VLE +++HGLKPKK IL        +  + +PV+  + K  +  E I T ++ M  +K+ LGR R +L++ LMQK+L +YF + I  +   L  +Y P A +LEE G+ I+G LVGL+VIDCN     D   D D  +G +++S Y+K D   +      + +  +  + ++LDQKNY EELN  L   +TNLQ     ++      +  LA   N  L L EE ++L+ E   L++ Y  K +  Q D+ VER TY TSRQ L+ L  + +K+ +EE+Q+R+D +K L+ ++  +T++E+ M  LEK V EKQ T++SLRKQ++++K IN+EL    +      +HK+ LV KLEEKT  M   +  M+ R+K+  S+K+ +++   +   +L EK+   +  E ++    E    + K   +L+ E+  +S+  S +  Q+  V++E S   KR         +Q +AL ++   L  SKL+ + LRE Q + +EA+W DD E   C  C K F++SRRKHHCR CG +YC ECS N+M L SS+KP+RVCD CH  LL+ Y++
Sbjct:   50 IERSNLLHVAKLVIKELIDSSLSQGRMLDDDFVPLQQFFVVLEHVLRHGLKPKKSILR-------DKREFFPVLEQIEKHVSEAEEITTSVRDMPNLKTPLGRARAFLRLALMQKRLADYFKVLIDKKDDVLVDFYEPGAFMLEEEGIVISGLLVGLNVIDCNICIKED---DLDEPMGVIDFSLYLK-DNSFLGQNEEEDGSEGNAKMAAILDQKNYLEELNRHLNATVTNLQQKMEAVQTSNTLMREDLAISKNNILALQEENSQLRHEKEGLETSYQRKMESAQADLSVERETYITSRQGLDHLYADSKKREEEEIQMRMDLEKELELQIGMKTEMEMAMRLLEKDVHEKQDTVVSLRKQLDEIKQINLELYNKLQACDGSLKHKTELVAKLEEKTNQMQEAMRAMEARVKQCESDKIAAEETARKLGQQLAEKDSRRAALETDLRIEREWRGTVQK---TLEQERGKVSQLQSDLQ-QMGKVKQEYSDLMKRHESMKQTCEEQEKALTELGSHLSESKLKMEDLREAQQALKEAQWADDAEATNCKGCTKEFSLSRRKHHCRNCGDIYCSECSDNKMPLPSSAKPVRVCDNCHTLLLQRYSA 640
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. TrEMBL
Match: A0A2R2MRA7 (RUN and FYVE domain-containing protein 2-like OS=Lingula unguis OX=7574 GN=LOC106154810 PE=4 SV=1)

HSP 1 Score: 334.724 bits (857), Expect = 5.907e-101
Identity = 227/606 (37.46%), Postives = 355/606 (58.58%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKK-ILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIET-IQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHI-ITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKR-------IYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            IER N++H+ KLV+K+++  ++   R LD+D   + Q   VLE +++HGLKPKK IL        +  + +PV+  + K  +  E I T ++ M  +K+ LGR R +L++ LMQK+L +YF + I  +   L  +Y P A +LEE G+ I+G LVGL+VIDCN     D   D D  +G +++S Y+K D   +      + +  +  + ++LDQKNY EELN  L   +TNLQ     ++      +  LA   N  L L EE ++L+ E   L++ Y  K +  Q D+ VER TY TSRQ L+ L  + +K+ +EE+Q+R+D +K L+ ++  +T++E+ M  LEK V EKQ T++SLRKQ++++K IN+EL    +      +HK+ LV KLEEKT  M   +  M+ R+K+  S+K+ +++   +   +L EK+   +  E ++    E    + K   +L+ E+  +S+  S +  Q+  V++E S   KR         +Q +AL ++   L  SKL+ + LRE Q + +EA+W DD E   C  C K F++SRRKHHCR CG +YC ECS N+M L SS+KP+RVCD CH  LL+ Y++
Sbjct:   50 IERSNLLHVAKLVIKELIDSSLSQGRMLDDDFVPLQQFFVVLEHVLRHGLKPKKSILR-------DKREFFPVLEQIEKHVSEAEEITTSVRDMPNLKTPLGRARAFLRLALMQKRLADYFKVLIDKKDDVLVDFYEPGAFMLEEEGIVISGLLVGLNVIDCNICIKED---DLDEPMGVIDFSLYLK-DNSFLGQNEEEDGSEGNAKMAAILDQKNYLEELNRHLNATVTNLQQKMEAVQTSNTLMREDLAISKNNILALQEENSQLRQEKEGLETSYQRKMESAQADLSVERETYITSRQGLDHLYADSKKREEEEIQMRMDLEKELELQIGMKTEMEMAMRLLEKDVHEKQDTVVSLRKQLDEIKQINLELYNKLQACDGSLKHKTELVAKLEEKTNQMQEAMRAMEARVKQCESDKIAAEETARKLGQQLAEKDSRRAALETDLRIEREWRGTVQK---TLEQERGKVSQLQSDLQ-QMGKVKQEYSDLMKRHESMKQTCEEQEKALTELGSHLSESKLKMEDLREAQQALKEAQWADDAEATNCKGCTKEFSLSRRKHHCRNCGDIYCSECSDNKMPLPSSAKPVRVCDNCHTLLLQRYSA 640
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. TrEMBL
Match: A0A0B7A585 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF94186 PE=4 SV=1)

HSP 1 Score: 322.013 bits (824), Expect = 1.372e-96
Identity = 217/613 (35.40%), Postives = 354/613 (57.75%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKK-ILNSVTIAGFNNLDPWPVICDLLK-KQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHI-ITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLIS--------------DQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            IER N+++++KL++K+++  ++   R LD+D   + Q   VLE +++HGLKPKK IL+S         + W V+  + K    + EI  ++++M  I++ LGR R WL++ LMQK L +YF + I  +   L  +Y   A +LEE GV IAG LVGL+V+DCN     +   D D  +G +++S YMK D    DS +  E  +    + ++LDQKNY EELN  L   +TNLQ    L++ +    K  LA   N  ++L  E+ +L GE N +   ++ K +  + DI  ER TY TSR  L+IL  +  K+L++E ++RLD +K L+ ++  +T++E+ +  LEK + EKQ T++ LRKQ++ +K IN+++    +  ++  +HK+ +V +LEEKT  + + +  ++QR+K+  SEK+ +              DQ     +T L+ +++  +  +   ++  EK+     E+  LK  K D S  ++K         +EL +   +  +Q  AL ++   L  SKL+ + +RE  A  +EA W  D+   QC QC+K F+++RRKHHCR CG ++C ECS N+M L SSSKP+RVCD C + LL+ Y++
Sbjct:   19 IERANLLNISKLLIKELIDSSLAHGRMLDDDYIPLQQFFVVLEHVLRHGLKPKKGILSS-------KKEFWWVLESIEKIAPEAAEITTSVREMPNIRTPLGRARAWLRLALMQKSLADYFKLMIEKRDILLHDFYETGAFMLEEEGVVIAGLLVGLNVLDCNMCIKGE---DLDQPMGVIDFSLYMK-DGKYNDS-TEDESGDGSSKMATILDQKNYLEELNRHLTATVTNLQQKLELVQADNCLMKEDLAISKNTIISLQTEVERLTGEKNDVTCGFEKKMEAAKQDIDAERETYLTSRAGLDILYADARKQLEDETKLRLDVEKELELQIGMKTEMEVALRLLEKDIHEKQDTVIGLRKQLDDIKTINLDMYNKLQACESSVKHKTEMVSRLEEKTNQLVSALKDLEQRLKQSESEKVAAVETARKLGQIVAEKDQKRSALETSLQIEKEWRTSLQANYEQEKEKLAHTQLEIAQLKDLKRDYSALIAK--------HEELRV---QCQEQESALAELGSHLSESKLKVEDMREASAMQREAHWASDETAMQCKQCSKDFSLARRKHHCRSCGDIFCAECSDNKMPLPSSSKPVRVCDNCQSKLLQRYSA 608
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. TrEMBL
Match: A0A0B7A519 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF94194 PE=4 SV=1)

HSP 1 Score: 322.013 bits (824), Expect = 5.613e-96
Identity = 217/613 (35.40%), Postives = 354/613 (57.75%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKK-ILNSVTIAGFNNLDPWPVICDLLK-KQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHI-ITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLIS--------------DQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            IER N+++++KL++K+++  ++   R LD+D   + Q   VLE +++HGLKPKK IL+S         + W V+  + K    + EI  ++++M  I++ LGR R WL++ LMQK L +YF + I  +   L  +Y   A +LEE GV IAG LVGL+V+DCN     +   D D  +G +++S YMK D    DS +  E  +    + ++LDQKNY EELN  L   +TNLQ    L++ +    K  LA   N  ++L  E+ +L GE N +   ++ K +  + DI  ER TY TSR  L+IL  +  K+L++E ++RLD +K L+ ++  +T++E+ +  LEK + EKQ T++ LRKQ++ +K IN+++    +  ++  +HK+ +V +LEEKT  + + +  ++QR+K+  SEK+ +              DQ     +T L+ +++  +  +   ++  EK+     E+  LK  K D S  ++K         +EL +   +  +Q  AL ++   L  SKL+ + +RE  A  +EA W  D+   QC QC+K F+++RRKHHCR CG ++C ECS N+M L SSSKP+RVCD C + LL+ Y++
Sbjct:   68 IERANLLNISKLLIKELIDSSLAHGRMLDDDYIPLQQFFVVLEHVLRHGLKPKKGILSS-------KKEFWWVLESIEKIAPEAAEITTSVREMPNIRTPLGRARAWLRLALMQKSLADYFKLMIEKRDILLHDFYETGAFMLEEEGVVIAGLLVGLNVLDCNMCIKGE---DLDQPMGVIDFSLYMK-DGKYNDS-TEDESGDGSSKMATILDQKNYLEELNRHLTATVTNLQQKLELVQADNCLMKEDLAISKNTIISLQTEVERLTGEKNDVTCGFEKKMEAAKQDIDAERETYLTSRAGLDILYADARKQLEDETKLRLDVEKELELQIGMKTEMEVALRLLEKDIHEKQDTVIGLRKQLDDIKTINLDMYNKLQACESSVKHKTEMVSRLEEKTNQLVSALKDLEQRLKQSESEKVAAVETARKLGQIVAEKDQKRSALETSLQIEKEWRTSLQANYEQEKEKLAHTQLEIAQLKDLKRDYSALIAK--------HEELRV---QCQEQESALAELGSHLSESKLKVEDMREASAMQREAHWASDETAMQCKQCSKDFSLARRKHHCRSCGDIFCAECSDNKMPLPSSSKPVRVCDNCQSKLLQRYSA 657
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Cavefish
Match: rufy1 (RUN and FYVE domain containing 1 [Source:NCBI gene;Acc:103027503])

HSP 1 Score: 274.633 bits (701), Expect = 4.066e-81
Identity = 199/630 (31.59%), Postives = 331/630 (52.54%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLS---------------------------KKRIY----DQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALL-KSYTS 2013
            +ER N++ + KL +K +++ ++   R LD D P + Q   VLE  +KHGLK KK       + +  L+    +C       S ++  +++ M G+K+GLGR R WL + LMQK++ +Y  ++ ++   L  +Y P A+LLEE G  I G LVGL+VID N L ++   +DS + I  +++S Y+K           +E    D  + ++LDQK+Y EELN  L   +T+LQ   + LE+   N K++  L+  T+R   L EE ++L+ EN  +      K ++   D QVE  TY+ SRQ L+ +   +  + KEE +IR +  K L+ ++  + ++E+ M  LEK + EKQ T+ +LR+Q++Q+K +N+++    +E   V   K     KLE+K   M   + +++ R++   +++  +++                  +++   E+  ++  L K +  L T +  L  +LSK   Q   +++EL                              KK++     +Q +AL++M   L  SKL+ +  +E+  + +   W  D E  QC QC K F++SRRKHHCR CG +YC  CSSN ++L S  KP+RVCD CH+ LL +S TS
Sbjct:  109 VERSNLLSMMKLSIKVLIQSSLSLGRTLDSDYPPLQQFFVVLEHCLKHGLKVKKSFIGQNKSIWAPLELVEKLCP-----ESADLATSVRDMPGLKTGLGRARAWLHLALMQKKVADYMKVLINRRDLLSEFYEPGALLLEEEGSVIVGMLVGLNVIDAN-LCVKGEDLDSQVGI--IDFSLYLK-------DPQTTENTQDDSKMTAILDQKHYIEELNRHLSCTVTDLQAKMDSLEK--TNCKLIEELSAATDRINALREEQDQLRQENATILQSSQRKEEVTLQDSQVELETYRQSRQGLDEMYNVVWTQYKEEKRIRQELQKELELQIGLKQEMEVAMKLLEKDIHEKQDTLAALRQQLDQVKTLNLQMFNKAQEAGGVAVKKEEDAVKLEQKMVQMEKAMKELELRLQDSENQRKNTEE-----------------GQKDLCSEMKGRVEALQKRMTDLDTLRSGLEVELSKEKEQRQSLQRELQREQDNSSELRTQLQQLQGLQTELLDLRHEKKQLQQLCEEQEQALQEMGLHLSQSKLKMEDFKEVNKALKGQAWLKDDEATQCKQCQKEFSISRRKHHCRNCGDIYCSSCSSNELALPSYPKPVRVCDICHSLLLQRSSTS 704
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Cavefish
Match: rufy2 (RUN and FYVE domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-070424-66])

HSP 1 Score: 252.292 bits (643), Expect = 7.545e-74
Identity = 176/537 (32.77%), Postives = 294/537 (54.75%), Query Frame = 1 
Query:  478 EIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLIS-DQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSE------KLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKL-----------LENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SAV+LEE G  I G LVGL+VID N     +   D D  +G +++S Y+K D D+  S    E N     I ++LDQKNY EELN  L   +  LQ   + LE+  +N K++  LA   N  + L EE ++L+ EN+ +      + ++ + D   E  TY+ SRQ L+ +  E  ++L+EE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR Q++++KAIN+E+ +  +      +HK+ ++ +LEEKT  +   + Q++QR++    ++L + D +         + +       +   ++ +   DL  E +  +T + DL        +LS    Q+N ++KE      R+ D++  L+ + +            L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S T+
Sbjct:   77 EIAASVRDLPGLKTPLGRARAWLRLALMQKRLADYLRVLITRKDILSDFYESSAVMLEEEGAVIVGLLVGLNVIDANLCVKGE---DLDTQVGVIDFSMYLKNDIDDYRS---EERNGQ---IAAILDQKNYVEELNRQLNSTVQGLQGRVDSLEK--SNSKLIEELAIAKNNIIKLQEENHQLRTENSVILMKAQQRLEVAKGDASCELDTYKQSRQGLDEMYNEARRQLREECQLRQDVENELVVQVSMKQEMELAMKLLEKDIHEKQDTLIGLRNQLDEVKAINVEMYQKMQTSDDGMKHKNDMIARLEEKTNQITATMRQLEQRLQDAERDRLSAEDGMRRFKHDFANKADSLQKQIAQREKQMLQLETDLKIEREWRQTLQNDLERERETVAQLSAEAQQINALKKEFH----RLQDENTQLKGICEEQEQALEELGCKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLPASPKPVRVCDTCHALLLQRCSSNTT 598
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Cavefish
Match: rufy2 (RUN and FYVE domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-070424-66])

HSP 1 Score: 251.521 bits (641), Expect = 3.943e-73
Identity = 176/537 (32.77%), Postives = 294/537 (54.75%), Query Frame = 1 
Query:  478 EIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLIS-DQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSE------KLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKL-----------LENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SAV+LEE G  I G LVGL+VID N     +   D D  +G +++S Y+K D D+  S    E N     I ++LDQKNY EELN  L   +  LQ   + LE+  +N K++  LA   N  + L EE ++L+ EN+ +      + ++ + D   E  TY+ SRQ L+ +  E  ++L+EE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR Q++++KAIN+E+ +  +      +HK+ ++ +LEEKT  +   + Q++QR++    ++L + D +         + +       +   ++ +   DL  E +  +T + DL        +LS    Q+N ++KE      R+ D++  L+ + +            L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S T+
Sbjct:  136 EIAASVRDLPGLKTPLGRARAWLRLALMQKRLADYLRVLITRKDILSDFYESSAVMLEEEGAVIVGLLVGLNVIDANLCVKGE---DLDTQVGVIDFSMYLKNDIDDYRS---EERNGQ---IAAILDQKNYVEELNRQLNSTVQGLQGRVDSLEK--SNSKLIEELAIAKNNIIKLQEENHQLRTENSVILMKAQQRLEVAKGDASCELDTYKQSRQGLDEMYNEARRQLREECQLRQDVENELVVQVSMKQEMELAMKLLEKDIHEKQDTLIGLRNQLDEVKAINVEMYQKMQTSDDGMKHKNDMIARLEEKTNQITATMRQLEQRLQDAERDRLSAEDGMRRFKHDFANKADSLQKQIAQREKQMLQLETDLKIEREWRQTLQNDLERERETVAQLSAEAQQINALKKEFH----RLQDENTQLKGICEEQEQALEELGCKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLPASPKPVRVCDTCHALLLQRCSSNTT 657
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Cavefish
Match: rufy3 (RUN and FYVE domain containing 3 [Source:NCBI gene;Acc:103035790])

HSP 1 Score: 242.276 bits (617), Expect = 6.293e-70
Identity = 189/617 (30.63%), Postives = 315/617 (51.05%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQT--SVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRI-YDQSEALEDMAKLLENSKLETDGLREM-----QASFQEARWTDDKEVNQ--------CIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            IER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G N     P+  +L++K T  + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y   I ++   L  +Y P+A+++EE G  IAG LVGL+VID N L ++   +DS   +G +++S Y+K      D    S+    D  I ++LDQKNY EELN  L   + NLQ   + LE+  +N K+   LA   NR + L EE+ ++K E++YL    +   K  + D   +      +R++L               Q+RLD +K L+ ++  R ++E+ M  LEK + EK   ++ LR+Q+E ++ +N EL+   +  ++  + K+ ++ +LEEKT  MA+ I Q++ R K+   +K ++++                        E  +KI  L +EV+ L+ ++  L  +L K   +      +  L K     D  + +ED+ K LE  K E D LR +       S   +   +D++           C  C  P +++R K  C+ C  V+C  C +N + L SS  P  VC+TC++ L++ Y S  +
Sbjct:   67 IERLNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKSKK-----TFLGQNKSFWGPL--ELVEKLTPEAGEITASVKDLPGLKTPLGRGRAWLRLALMQKKLSDYMKTIINRKDLLSEFYEPNALMMEEEGAVIAGLLVGLNVIDAN-LCMKGEDLDS--QVGVIDFSMYLK------DGGHSSKSTEGDGQITAILDQKNYVEELNRHLSASVNNLQAKVDALEK--SNTKLTEELAVANNRIITLQEEVERVKEESSYL---VESSRKASRPDGAADGQVLGETRKQLKEE-----------TQLRLDVEKELEVQIGMRQEMELSMKMLEKDICEKHDALVELRQQLEDVRRLNHELSHKSQSSESSIKQKAEIISRLEEKTNQMASTIKQLENRSKQAEKQKDLAEE-----------------ANRLFKQEFGDKIESLQQEVEQLRRQRSSLEHELRKERDRRGGPPSDALLGKTPPQRDVRQQVEDIKKELETVKKENDTLRNVLEEKTSLSSSLSCSHEDEQEQPCEEPEPFICQMCECPESLTRPKGECKNCREVFCESCITNELPLPSSINPEHVCNTCYSTLMQQYASTPT 634
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Cavefish
Match: rufy3 (RUN and FYVE domain containing 3 [Source:NCBI gene;Acc:103035790])

HSP 1 Score: 242.662 bits (618), Expect = 9.861e-70
Identity = 188/617 (30.47%), Postives = 315/617 (51.05%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQT--SVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRI-YDQSEALEDMAKLLENSKLETDGLREM-----QASFQEARWTDDKEVNQ--------CIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            IER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G N     P+  +L++K T  + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y   I ++   L  +Y P+A+++EE G  IAG LVGL+VID N L ++   +DS + +  +++S Y+K      D    S+    D  I ++LDQKNY EELN  L   + NLQ   + LE+  +N K+   LA   NR + L EE+ ++K E++YL    +   K  + D   +      +R++L               Q+RLD +K L+ ++  R ++E+ M  LEK + EK   ++ LR+Q+E ++ +N EL+   +  ++  + K+ ++ +LEEKT  MA+ I Q++ R K+   +K ++++                        E  +KI  L +EV+ L+ ++  L  +L K   +      +  L K     D  + +ED+ K LE  K E D LR +       S   +   +D++           C  C  P +++R K  C+ C  V+C  C +N + L SS  P  VC+TC++ L++ Y S  +
Sbjct:  103 IERLNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKSKK-----TFLGQNKSFWGPL--ELVEKLTPEAGEITASVKDLPGLKTPLGRGRAWLRLALMQKKLSDYMKTIINRKDLLSEFYEPNALMMEEEGAVIAGLLVGLNVIDAN-LCMKGEDLDSQVGV--IDFSMYLK------DGGHSSKSTEGDGQITAILDQKNYVEELNRHLSASVNNLQAKVDALEK--SNTKLTEELAVANNRIITLQEEVERVKEESSYL---VESSRKASRPDGAADGQVLGETRKQLKEE-----------TQLRLDVEKELEVQIGMRQEMELSMKMLEKDICEKHDALVELRQQLEDVRRLNHELSHKSQSSESSIKQKAEIISRLEEKTNQMASTIKQLENRSKQAEKQKDLAEE-----------------ANRLFKQEFGDKIESLQQEVEQLRRQRSSLEHELRKERDRRGGPPSDALLGKTPPQRDVRQQVEDIKKELETVKKENDTLRNVLEEKTSLSSSLSCSHEDEQEQPCEEPEPFICQMCECPESLTRPKGECKNCREVFCESCITNELPLPSSINPEHVCNTCYSTLMQQYASTPT 670
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Sea Lamprey
Match: rufy3 (RUN and FYVE domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-050327-58])

HSP 1 Score: 119.783 bits (299), Expect = 5.991e-31
Identity = 71/224 (31.70%), Postives = 123/224 (54.91%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQ 897
            +ER N++++ KL +K ++  A+   R LD D   + Q   +LE  +KHGLK KK     + + +  L+    +C       + EI  +++ + G+K+ +GR R WL++ LMQK L +Y   + ++   L  +Y P +++LEE G  I+G +VGL+V+D N     +   D D  +G ++++ Y+K           S  +N +  + ++LDQKNY EELN  L+
Sbjct:   10 LERLNLMNMAKLSIKSLIEAALALGRSLDSDYAPLQQFFVILEHCLKHGLKVKKSFLGQSKSFWGPLELVERLC-----PEAAEIAVSVRDLPGLKTPVGRGRAWLRLALMQKTLSDYMKALVARKDLLSEFYEPGSLMLEEEGAVISGMMVGLNVLDANLCMKGE---DLDTQVGIIDFTMYLKD--------GSSSDDNGNANMTAVLDQKNYLEELNRGLK 217
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001934.1 (pep scaffold:Pmarinus_7.0:GL488632:1056:3278:1 gene:ENSPMAG00000001758.1 transcript:ENSPMAT00000001934.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.449 bits (254), Expect = 5.092e-26
Identity = 44/106 (41.51%), Postives = 67/106 (63.21%), Query Frame = 1 
Query: 1696 KKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            K  + +Q + L+++   L  SKL+ + ++E+  + Q   W  D++   C  C K F++SRRKHHCR CG ++C+ CS N + L SS KP+RVCD CH  LL+ Y+S
Sbjct:   16 KGALDEQEQTLQELGGKLSESKLKMEDIKEVNKALQGQVWLKDQDATNCKLCEKEFSISRRKHHCRNCGEIFCNSCSDNELPLPSSPKPVRVCDLCHALLLQRYSS 121
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Sea Lamprey
Match: eea1 (early endosome antigen 1 [Source:ZFIN;Acc:ZDB-GENE-041111-270])

HSP 1 Score: 90.1225 bits (222), Expect = 1.151e-18
Identity = 30/58 (51.72%), Postives = 41/58 (70.69%), Query Frame = 1 
Query: 1810 RWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTC 1983
            +W +D EV  C+ C K F+V+ RKHHCR CG ++C ECS+    + S+ KP+RVCDTC
Sbjct: 1306 KWAEDGEVQNCMGCGKGFSVTVRKHHCRHCGNIFCGECSARNSMIPSAKKPVRVCDTC 1363
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005437.1 (pep scaffold:Pmarinus_7.0:GL486528:10206:16522:1 gene:ENSPMAG00000004933.1 transcript:ENSPMAT00000005437.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 7.740e-11
Identity = 31/98 (31.63%), Postives = 49/98 (50.00%), Query Frame = 1 
Query: 1735 MAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFN-VSRRKHHCRRCGGVYCHECSSNRMSLASSSKPM-RVCDTCHNALLKSYTSMTS 2022
            M      S +     + M+   +   W  D  V  C+ C  PF  ++RR+HHCR CG V C +CS +R+ LA   + + RVC+ C+  L +   + T+
Sbjct:  202 MGHTANVSDVSPPATQGMELGQRAPMWVRDVNVTLCMTCQDPFTTLTRRRHHCRACGKVVCWKCSDHRVLLAYEPRKLQRVCEACYAQLTEEARTSTA 299
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Sea Lamprey
Match: ankfy1 (ankyrin repeat and FYVE domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-041222-1])

HSP 1 Score: 62.003 bits (149), Expect = 4.568e-10
Identity = 27/67 (40.30%), Postives = 39/67 (58.21%), Query Frame = 1 
Query: 1801 QEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASS--SKPMRVCDTCHNAL 1995
            +E  W D    + C +CA  F V+ RKHHCR CG + C+ CS+  + +     +KP+RVCD C + L
Sbjct: 1099 KEPPWCDG---SNCYECAAKFGVTTRKHHCRHCGRLLCNRCSAKEIPIIKFDLNKPVRVCDICFDVL 1162
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Yeast
Match: VPS27 (Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289])

HSP 1 Score: 70.8626 bits (172), Expect = 3.415e-13
Identity = 45/117 (38.46%), Postives = 61/117 (52.14%), Query Frame = 1 
Query: 1648 KMNLQLNFVEKELSLSKKRIYDQ--SEALEDMAKL-LENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSS--KPMRVCDTC 1983
            K + QLN+V K        +YD+  S  ++   KL L NS         M  S   A W D    + C+ C+K F++  RKHHCR CGGV+C E SSN + L      +P+RVCD+C
Sbjct:  126 KNDSQLNYVAK--------VYDKLISRGIKFPEKLTLSNSPTA------MFDSKTPADWIDS---DACMICSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSC 225
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Yeast
Match: FAB1 (1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis [Source:SGD;Acc:S000001915])

HSP 1 Score: 58.5362 bits (140), Expect = 3.424e-9
Identity = 24/62 (38.71%), Postives = 32/62 (51.61%), Query Frame = 1 
Query: 1813 WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECS----SNRMSLASSSKPMRVCDTCH 1986
            W  D+   +C  C K FN  RRKHHCR CG ++C  C+     +R    +    MRVC  C+
Sbjct:  237 WMKDESSKECFSCGKTFNTFRRKHHCRICGQIFCSSCTLLIDGDRFGCHAK---MRVCYNCY 295
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Yeast
Match: PIB1 (RING-type ubiquitin ligase of the endosomal and vacuolar membranes; binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain [Source:SGD;Acc:S000002721])

HSP 1 Score: 56.6102 bits (135), Expect = 4.068e-9
Identity = 26/77 (33.77%), Postives = 38/77 (49.35%), Query Frame = 1 
Query: 1807 ARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLAS-------------SSKPMRVCDTCHNALL 1998
            ARW  D+E + C QC   F+   R+HHCR CG ++C  C+ N ++                 S P R C+ C++ LL
Sbjct:   12 ARWQADEEAHSCFQCKTNFSFLVRRHHCRCCGRIFCSSCTENFVNYNKKRVHALQKKNSDVESPPYRTCNECYDNLL 88
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Yeast
Match: PIB2 (Protein of unknown function; contains FYVE domain; similar to Fab1 and Vps27 [Source:SGD;Acc:S000002991])

HSP 1 Score: 51.6026 bits (122), Expect = 3.245e-7
Identity = 17/36 (47.22%), Postives = 22/36 (61.11%), Query Frame = 1 
Query: 1813 WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHE 1920
            W  D + N C  C KPF +  RKHHCR CG ++C +
Sbjct:  449 WIPDSKRNSCRYCHKPFTLWERKHHCRHCGDIFCQD 484
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Yeast
Match: PEP7 (Adaptor protein involved in vesicle-mediated vacuolar protein sorting; multivalent adaptor protein; facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance [Source:SGD;Acc:S000002731])

HSP 1 Score: 48.521 bits (114), Expect = 2.685e-6
Identity = 19/40 (47.50%), Postives = 25/40 (62.50%), Query Frame = 1 
Query: 1813 WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSN 1932
            W DD+ V  C  C++PF +  RKHHCR CG V C + + N
Sbjct:  212 WRDDRSVLFCNICSEPFGLLLRKHHCRLCGMVVCDDANRN 251
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Nematostella
Match: EDO44969 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU81])

HSP 1 Score: 147.902 bits (372), Expect = 2.042e-39
Identity = 100/304 (32.89%), Postives = 162/304 (53.29%), Query Frame = 1 
Query: 1171 VQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVD----SLKTEKE---DLSEKLSK-----MNLQLNF-------------VEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSY 2007
            +Q+R +T++ L+     + + E+ M  LEK + +KQ T++ LR+Q++ +K IN++L+   +  ++           LEE  A   N I +++ R+ K           +  S  +L+          E ++E   K++D   E      SLK E+E   +L E+L K      +LQ +              +EK  +L+K    +Q  AL +M   L  S+ + + ++E+  + +E +WTDDKE   C QC +PF++SRRKHHCR CGG++C  CSSN M L SS+KP+RVCD+CH ALL+ Y
Sbjct:   20 MQLRKETERELEMMRSMKEESEVAMRLLEKDIHDKQDTLIVLRRQLDDIKKINLDLHNKLQTCESSNRQHMEKCSALEENCARFVNQIKELEHRVLKLY---------MCSSDFRLKVVGAEKDQMMETLEEFKNKLSDTQSERSALETSLKIEREWRTNLQEELHKEKERIGSLQQSLRRMDALKKEYQTTLEKNAALAKVNA-EQETALVEMGYHLSTSQQKVEEMKEVTLTMKEMKWTDDKEALNCQQCEQPFSLSRRKHHCRSCGGIFCQPCSSNTMPLPSSAKPVRVCDSCHTALLQRY 313
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Nematostella
Match: EDO44968 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU80])

HSP 1 Score: 96.2857 bits (238), Expect = 7.959e-23
Identity = 53/166 (31.93%), Postives = 95/166 (57.23%), Query Frame = 1 
Query:  217 SDFEIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLK-KQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNF 708
            S ++ ER N++++ KL +K ++  A++  + + E++    Q   ++E+I++HGLK K+ L           D W  +  L K    S EI  +++ +  IK+  G+ R W ++ LMQK+L +Y  II      +  +Y   A+L+++ G+ I+G LVG++VIDCNF
Sbjct:    6 SHWKTERLNLLNIAKLCIKTLIESALEVGKVIGEEHEPFQQFFVIIENILRHGLKLKRNLLG------QRRDYWAALEALEKIAPESAEITNSVRNLPSIKTSHGKGRAWTRLALMQKKLADYIRIIVENKAAMAEWYESHALLMQDEGIVISGLLVGINVIDCNF 165
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Nematostella
Match: EDO38501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCW3])

HSP 1 Score: 72.7886 bits (177), Expect = 2.003e-14
Identity = 37/118 (31.36%), Postives = 61/118 (51.69%), Query Frame = 1 
Query: 1648 KMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKP-FNVSRRKHHCRRCGGVYCHECSSNRMSL-ASSSKPMRVCDTCHNAL 1995
            K   Q+   +K  ++      +++E +  + K +++   +T    +       A W  D E + C+ C K  F    R+HHCR+CG V C  CS+ +  L A SSKP+RVC++C+N L
Sbjct:   99 KNGWQIISTKKSFAVYAATATEKAEWMAHINKCIQDLLAKTG---KKAGGVHAAVWVPDSEASTCMSCMKTKFTAINRRHHCRKCGAVVCGACSTKKFLLPAQSSKPLRVCNSCYNTL 213
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Nematostella
Match: EDO44615 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVB5])

HSP 1 Score: 75.0998 bits (183), Expect = 2.154e-14
Identity = 29/73 (39.73%), Postives = 41/73 (56.16%), Query Frame = 1 
Query: 1777 LREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNAL 1995
            L EMQ S  E RW    +  +C  C KP N ++ K+HC  CG ++C  C S   S +S+ +P +VCD C+  L
Sbjct:  300 LAEMQESENEVRWEHKDDARECRNCQKPLNTNKDKYHCHHCGKIFCEGCRSKTFSNSSTRRPHQVCDACYATL 372
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Nematostella
Match: EDO48184 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK38])

HSP 1 Score: 64.6994 bits (156), Expect = 2.204e-12
Identity = 29/75 (38.67%), Postives = 42/75 (56.00%), Query Frame = 1 
Query: 1777 LREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSL-ASSSKPMRVCDTCHNALL 1998
            LR+ +   +   W  D+ V  C+ C   F ++RR+HHCR CGG+YC+ CS N+  L     K  RVC +C   L+
Sbjct:    1 LRDNELGTKAPAWIRDESVTMCMLCDALFTLTRRRHHCRACGGIYCNACSHNKAPLEYRDGKLCRVCRSCREILV 75
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Medaka
Match: rufy2 (RUN and FYVE domain containing 2 [Source:NCBI gene;Acc:101165874])

HSP 1 Score: 303.908 bits (777), Expect = 4.308e-92
Identity = 212/615 (34.47%), Postives = 349/615 (56.75%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKK--QTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKI-NDLIKEVDSLKTEKEDLSE------KLSKMNLQLNFVEKELS-LSKKRIY------DQSEALEDMAKLLENSKLETDGLREMQASFQEAR-WTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            +ER N++++ KL +K ++  A+   R LD D P + Q   V+E  +KHGLK KK     +  G+N     P+  +L++K    + EI  +++ + G+K+ LGR R WL++ LMQK+L +Y  ++ ++   L  +Y  SA++LEE G  I G LVGL+VID N L ++   +DS   +G +++S Y+K D D+  S    E  N+   I S+LDQKNY EELN  L   +  LQ   + LE+  +N K++  LA   N  + L EE  +L+ ENN +        ++ Q D+ +ER TY+ SRQ L+ +  E  ++LKEE Q+R D +  L  +V  + ++E+ M  LEK + EKQ T++ LR+Q++++KAIN+E+ +  +      + K+ ++ +LEEKT  +   + Q++QR+++    +  +++     K     K  +   + E  ++L +++  DL  E +  +T + DL        +L    LQ+N ++KE   L  + I       DQ +ALE++   L  SKL+ + ++E   + Q  + W  DK+   C  C K F++SRRKHHCR CG ++C+ CS N + L +S KP+RVCDTCH  LL+  +S
Sbjct:  104 MERTNLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKVKK-----SFLGYNKSLWGPL--ELVEKLCPEAAEISASVRDLPGLKTPLGRARAWLRLALMQKRLADYLRLLITRKDLLSDFYETSALMLEEEGAVIVGLLVGLNVIDAN-LCVKGEDLDS--QVGVIDFSMYLKNDIDDYRS----EERNSQ--IASILDQKNYVEELNRQLNSTVHGLQGRVDSLEK--SNSKLIEELAIAKNNIIKLQEENQQLRSENNLILLKAQQHLEVTQGDVSLERDTYKQSRQGLDEMYNEARRQLKEECQLRQDVENELVVQVSMKQEMELAMKLLEKDIHEKQDTLIGLRQQLDEVKAINVEMYQKMQSSSEEMKKKNDMISRLEEKTNQITATMKQLEQRLQEAERHRTSAEEGTRRFKLDFANKADSLQRQIEHKEKLLQQLETDLKIEREWRQTLQNDLHREKDTVAQLGTEALQINGLKKEFHRLQDENIQLKNICEDQEQALEELGSKLSESKLKIEDIKEANKALQGGQVWLKDKDATHCKMCEKEFSISRRKHHCRNCGEIFCNSCSDNELPLPASPKPVRVCDTCHALLLQRCSS 700
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Medaka
Match: rufy1 (RUN and FYVE domain-containing protein 1 [Source:NCBI gene;Acc:101155857])

HSP 1 Score: 281.182 bits (718), Expect = 3.816e-83
Identity = 203/615 (33.01%), Postives = 337/615 (54.80%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKI-NDLIKEVD-------SLKTEKEDLSE------KLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            IER N++ + KL +K +++ ++   R LD + P + Q   VLE  +KHGLK KK       + +  L+    +C       S  I  + + + GI++GLGR R WL + LMQK++ +Y   +      L  +Y   A++LEE G  + G LVGL+VID N L ++   +DS   +G +++S Y+K      D  S SE    D  + ++LDQK+Y EELN  L   +T+LQ   + +E+   N K++  L   T+R  +L +E  +LK EN  +      K +    D QVE  TY+ +RQ L+ +   + ++ KEE +IR +  + L+ +V  + ++E+ M  LEK   EKQ T+ +LR Q+EQ+K +N+++    +E +   E K     KLE++   M   +++M+QR++    E+  SDQ   + K +LE K      +  ++D L   + N+L  E +       +L+ E+++ SE      +L  ++++L  +++E    ++R   Q +AL++M   L  SKL+ +  +E+  + +   W  D E  QC QC K F+++RRKHHCR CG +YC+ CSSN ++L S  +P+RVCD CH  LL+  +S  S
Sbjct:  164 IERSNLLSMMKLSIKVLIQSSLSLGRTLDSEYPPLQQFFVVLEQCLKHGLKTKKSFIGQNKSIWGPLELVEKLCP-----ESANIATSARDLPGIRTGLGRGRAWLHLALMQKKIADYIKALLDHKDLLSEFYDSGAMMLEEEGSVLGGLLVGLNVIDAN-LCIKGEDLDS--QVGVIDFSLYLK------DPAS-SETPKDDANMTAILDQKHYIEELNRHLSGTVTDLQAKLDSIEK--TNSKLVEELTAATDRINSLQDEQEQLKKENESILQCSQKKEEAALQDSQVELETYKQTRQGLDEMYNVVWQQYKEEKRIRQELQRELELQVGLKQEMEVAMKLLEKDSHEKQDTLAALRLQLEQVKTLNLQMFHRAQESERQAEKKQEEAVKLEQRMKDMEKAMEEMEQRLQNSECERKQSDQSDEDMKVELEGKVDALQTQLTDLDTLRLGLENELRTEREQRQSLQKALQREQDNSSELRTQLQQLQGLHVELQELKQEKQQLQERCEQQEQALQEMGLHLSQSKLKMEDFKEVNKALKGHAWLKDDEATQCKQCQKEFSIARRKHHCRNCGDIYCNSCSSNELALPSYPRPVRVCDVCHALLLQRSSSTAS 761
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Medaka
Match: rufy1 (RUN and FYVE domain-containing protein 1 [Source:NCBI gene;Acc:101155857])

HSP 1 Score: 255.373 bits (651), Expect = 2.770e-75
Identity = 197/601 (32.78%), Postives = 318/601 (52.91%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTS 2022
            IER N++ + KL +K +++ ++   R LD + P + Q   VLE  +KHGLK KK       + +  L+    +C       S  I  + + + GI++GLGR R WL + LMQK++ +Y   +      L  +Y   A++LEE G  + G LVGL+VID N L ++   +DS   +G +++S Y+K      D  S SE    D  + ++LDQK+Y EELN  L   +T+LQ   + +E+   N K++  L   T+R  +L +E  +LK EN  +      K +    D QVE  TY+ +RQ L+ +   + +      Q + +  K LQ  V  + ++E+ M  LEK   EKQ T+ +LR Q+EQ+K +N+++   F  +Q   E K     KLE++   M    DQ D+ +K  +  K+ + Q  L     L    +     E E  +  +K   L +E D+    +  L ++L  ++++L  +++E    ++R   Q +AL++M   L  SKL+ +  +E+  + +   W  D E  QC QC K F+++RRKHHCR CG +YC+ CSSN ++L S  +P+RVCD CH  LL+  +S  S
Sbjct:    3 IERSNLLSMMKLSIKVLIQSSLSLGRTLDSEYPPLQQFFVVLEQCLKHGLKTKKSFIGQNKSIWGPLELVEKLCP-----ESANIATSARDLPGIRTGLGRGRAWLHLALMQKKIADYIKALLDHKDLLSEFYDSGAMMLEEEGSVLGGLLVGLNVIDAN-LCIKGEDLDS--QVGVIDFSLYLK------DPAS-SETPKDDANMTAILDQKHYIEELNRHLSGTVTDLQAKLDSIEK--TNSKLVEELTAATDRINSLQDEQEQLKKENESILQCSQKKEEAALQDSQVELETYKQTRQGLDEMYNVVWQ------QYKEEKLKLLQ--VGLKQEMEVAMKLLEKDSHEKQDTLAALRLQLEQVKTLNLQM---FHRRQA--EKKQEEAVKLEQRMKDMEKS-DQSDEDMKVELEGKVDALQTQLTDLDTLRLGLENELRTEREQRQSLQKA--LQREQDNSSELRTQL-QQLQGLHVELQELKQEKQQLQERCEQQEQALQEMGLHLSQSKLKMEDFKEVNKALKGHAWLKDDEATQCKQCQKEFSIARRKHHCRNCGDIYCNSCSSNELALPSYPRPVRVCDVCHALLLQRSSSTAS 569
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Medaka
Match: rufy3 (RUN and FYVE domain containing 3 [Source:NCBI gene;Acc:101160300])

HSP 1 Score: 189.889 bits (481), Expect = 6.850e-52
Identity = 137/425 (32.24%), Postives = 235/425 (55.29%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQT--SVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNY-LKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLIS 1485
            IER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G  N   W  + +L++K T  + EI  +++ + G+++ LGR R WL++ LMQK+L +Y   I ++   L  +Y P+A+++EE G  IAG LVGL+VID N L ++   +DS   +G +++S Y+K      D    S+    D  I ++LDQKNY EELN  L   + NLQ   + LE+  AN K+   LA   NR + L E++ ++K E+++ L+S      K  + D   + S    +R++L    +           +RLD ++ L+ ++  + ++E+ M  LEK V EKQ  ++ LR+Q++ L+ IN +L+   +   +  + K  ++ +LE+K + M+  + Q++ R K    E+ ++
Sbjct:   67 IERLNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKTKK-----TFLG-QNKSFWGAL-ELVEKLTPEAGEITASVKDLPGLRTPLGRGRAWLRLALMQKKLSDYMKTIINRKDLLSEFYEPNALMMEEEGAVIAGLLVGLNVIDAN-LCMKGEDLDS--QVGVIDFSMYLK------DGGHSSKSAEGDGQITAILDQKNYVEELNRHLSASVNNLQAKVDALEK--ANTKLTEELAVANNRIITLQEDVERVKEESSFQLES-----RKSARGDPAADGSALTETRKQLKEETL-----------LRLDVERELEVQIGMKQEMEMSMKMLEKDVCEKQDALMELRQQLDDLRTINQQLSHKSQSADSSSKQKGEVIARLEDKISQMSGTVKQLESRCKHAERERALA 457
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Medaka
Match: rufy3 (RUN and FYVE domain containing 3 [Source:NCBI gene;Acc:101160300])

HSP 1 Score: 191.045 bits (484), Expect = 2.952e-51
Identity = 136/425 (32.00%), Postives = 235/425 (55.29%), Query Frame = 1 
Query:  229 IERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQT--SVEIIETIQQM-GIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIM--LADGTNRQLNLVEELNKLKGENNY-LKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLIS 1485
            IER N++++ KL +K ++  A+   R LD D   + Q   V+E  +KHGLK KK     T  G  N   W  + +L++K T  + EI  +++ + G+++ LGR R WL++ LMQK+L +Y   I ++   L  +Y P+A+++EE G  IAG LVGL+VID N L ++   +DS + +  +++S Y+K      D    S+    D  I ++LDQKNY EELN  L   + NLQ   + LE+  AN K+   LA   NR + L E++ ++K E+++ L+S      K  + D   + S    +R++L    +           +RLD ++ L+ ++  + ++E+ M  LEK V EKQ  ++ LR+Q++ L+ IN +L+   +   +  + K  ++ +LE+K + M+  + Q++ R K    E+ ++
Sbjct:   88 IERLNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKTKK-----TFLG-QNKSFWGAL-ELVEKLTPEAGEITASVKDLPGLRTPLGRGRAWLRLALMQKKLSDYMKTIINRKDLLSEFYEPNALMMEEEGAVIAGLLVGLNVIDAN-LCMKGEDLDSQVGV--IDFSMYLK------DGGHSSKSAEGDGQITAILDQKNYVEELNRHLSASVNNLQAKVDALEK--ANTKLTEELAVANNRIITLQEDVERVKEESSFQLES-----RKSARGDPAADGSALTETRKQLKEETL-----------LRLDVERELEVQIGMKQEMEMSMKMLEKDVCEKQDALMELRQQLDDLRTINQQLSHKSQSADSSSKQKGEVIARLEDKISQMSGTVKQLESRCKHAERERALA 478

HSP 2 Score: 54.6842 bits (130), Expect = 3.653e-7
Identity = 23/58 (39.66%), Postives = 30/58 (51.72%), Query Frame = 1 
Query: 1840 CIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTS 2013
            C  C +  ++ R K  C+ C GV+C  C SN + L SS  P  VC  C+  LL  Y S
Sbjct:  613 CAMCEEVQSLDRTKKRCKNCSGVFCQSCVSNELPLPSSILPETVCSACYAQLLLQYGS 670
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Planmine SMEST
Match: SMESG000050873.1 (SMESG000050873.1)

HSP 1 Score: 1176 bits (3041), Expect = 0.000e+0
Identity = 619/620 (99.84%), Postives = 620/620 (100.00%), Query Frame = 1 
Query:  184 MEFTKENNEILSDFEIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMGIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQXXXXXXXXXXXXXXXXVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIIXXXXXXXXXXXXXXXXXXXXIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTSRSDSDAS 2043
            MEFTKENNEILSDFEIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMGIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQELNILNIELEKKLKEEVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKF+SEKLISDQIILESKTKLEEKEKTCSLKEEEIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTSRSDSDAS
Sbjct:    1 MEFTKENNEILSDFEIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLIIQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEIIETIQQMGIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPSAVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKRDFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNLLEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDDIQVERSTYQTSRQELNILNIELEKKLKEEVQIRLDTDKSLQSEVQRRTDIEIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKSVLVDKLEEKTAGMANIIDQMDQRIKKFLSEKLISDQIILESKTKLEEKEKTCSLKEEEIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKELSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTCHNALLKSYTSMTSRSDSDAS 620
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Planmine SMEST
Match: SMESG000008512.1 (SMESG000008512.1)

HSP 1 Score: 85.5001 bits (210), Expect = 9.383e-17
Identity = 31/58 (53.45%), Postives = 39/58 (67.24%), Query Frame = 1 
Query: 1810 RWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTC 1983
            +W  D +  +C  C KPF+++ RKHHCR CG V C +CSS   SLA S KP+RVCD C
Sbjct: 1029 QWIGDLDAVECFTCHKPFSLTLRKHHCRNCGQVLCQDCSSKSASLAVSRKPVRVCDAC 1086
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Planmine SMEST
Match: SMESG000069357.1 (SMESG000069357.1)

HSP 1 Score: 74.3294 bits (181), Expect = 1.982e-13
Identity = 29/60 (48.33%), Postives = 35/60 (58.33%), Query Frame = 1 
Query: 1810 RWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASS--SKPMRVCDTC 1983
            RW  D  V  C  C   F  S RKHHCR CG ++CH CS+NR  +     + P+RVCDTC
Sbjct:  609 RWIPDHAVTHCSNCKIIFTFSLRKHHCRNCGRIFCHPCSNNRCPIPKQKLNYPVRVCDTC 668
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Planmine SMEST
Match: SMESG000051464.1 (SMESG000051464.1)

HSP 1 Score: 62.3882 bits (150), Expect = 1.193e-9
Identity = 30/84 (35.71%), Postives = 43/84 (51.19%), Query Frame = 1 
Query: 1738 AKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRM--SLASSSKPMRVCDTC 1983
            + LLENS++E    R          W  D    +C  C + F   +RKHHCR CG ++C+ C ++ +  SL + SKP R C  C
Sbjct:  104 STLLENSEIEATMDR-----IDREYWMPDSICRKCYSCEEEFTTIKRKHHCRMCGQIFCYRCCTDELPGSLWNLSKPQRSCKLC 182
[Close]
BLAST of RUN and FYVE domain-containing protein 2-like vs. Planmine SMEST
Match: SMESG000051464.1 (SMESG000051464.1)

HSP 1 Score: 62.3882 bits (150), Expect = 1.289e-9
Identity = 30/84 (35.71%), Postives = 43/84 (51.19%), Query Frame = 1 
Query: 1738 AKLLENSKLETDGLREMQASFQEARWTDDKEVNQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRM--SLASSSKPMRVCDTC 1983
            + LLENS++E    R          W  D    +C  C + F   +RKHHCR CG ++C+ C ++ +  SL + SKP R C  C
Sbjct:  104 STLLENSEIEATMDR-----IDREYWMPDSICRKCYSCEEEFTTIKRKHHCRMCGQIFCYRCCTDELPGSLWNLSKPQRSCKLC 182
The following BLAST results are available for this feature:
BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RUFY22.230e-8432.14RUN and FYVE domain containing 2 [Source:HGNC Symb... [more]
RUFY25.764e-8432.14RUN and FYVE domain containing 2 [Source:HGNC Symb... [more]
RUFY28.345e-8432.14RUN and FYVE domain containing 2 [Source:HGNC Symb... [more]
RUFY12.666e-8132.03RUN and FYVE domain containing 1 [Source:HGNC Symb... [more]
RUFY12.666e-8132.03RUN and FYVE domain containing 1 [Source:HGNC Symb... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eea-18.160e-1841.35EEA1 (Early Endosome Antigen, Rab effector) homolo... [more]
eea-18.367e-1841.35EEA1 (Early Endosome Antigen, Rab effector) homolo... [more]
lst-21.261e-1540.54Lateral signaling target protein 2 [Source:UniPro... [more]
ZK632.125.044e-1142.86pep chromosome:WBcel235:III:9830802:9832378:1 gene... [more]
ZK632.125.044e-1142.86pep chromosome:WBcel235:III:9830792:9832430:1 gene... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG310648.207e-5929.06gene:FBgn0051064 transcript:FBtr0085125[more]
CG310646.336e-5829.06gene:FBgn0051064 transcript:FBtr0339249[more]
CG310641.980e-3830.02gene:FBgn0051064 transcript:FBtr0085124[more]
CG310648.500e-3830.02gene:FBgn0051064 transcript:FBtr0339248[more]
CG310649.143e-3830.02gene:FBgn0051064 transcript:FBtr0085126[more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rufy22.023e-8833.28RUN and FYVE domain containing 2 [Source:ZFIN;Acc:... [more]
rufy22.023e-8833.28RUN and FYVE domain containing 2 [Source:ZFIN;Acc:... [more]
rufy24.663e-8833.28RUN and FYVE domain containing 2 [Source:ZFIN;Acc:... [more]
rufy24.663e-8833.28RUN and FYVE domain containing 2 [Source:ZFIN;Acc:... [more]
rufy26.228e-8833.12RUN and FYVE domain containing 2 [Source:ZFIN;Acc:... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fam43b2.061e-7931.08family with sequence similarity 43 member B [Sourc... [more]
fam43b2.666e-7931.08family with sequence similarity 43 member B [Sourc... [more]
fam43b4.381e-6830.90family with sequence similarity 43 member B [Sourc... [more]
rufy34.142e-5333.26RUN and FYVE domain containing 3 [Source:NCBI gene... [more]
rufy34.534e-5333.57RUN and FYVE domain containing 3 [Source:NCBI gene... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rufy27.983e-8432.20RUN and FYVE domain-containing 2 [Source:MGI Symbo... [more]
Rufy15.808e-8331.87RUN and FYVE domain containing 1 [Source:MGI Symbo... [more]
Rufy31.176e-6530.81RUN and FYVE domain containing 3 [Source:MGI Symbo... [more]
Rufy32.104e-5434.61RUN and FYVE domain containing 3 [Source:MGI Symbo... [more]
Rufy32.307e-5434.61RUN and FYVE domain containing 3 [Source:MGI Symbo... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8WXA3|RUFY2_HUMAN1.071e-8332.14RUN and FYVE domain-containing protein 2 OS=Homo s... [more]
sp|Q5R5R4|RUFY2_PONAB1.657e-8332.14RUN and FYVE domain-containing protein 2 OS=Pongo ... [more]
sp|Q8R4C2|RUFY2_MOUSE5.584e-8332.20RUN and FYVE domain-containing protein 2 OS=Mus mu... [more]
sp|Q8BIJ7|RUFY1_MOUSE4.063e-8231.87RUN and FYVE domain-containing protein 1 OS=Mus mu... [more]
sp|Q96T51|RUFY1_HUMAN2.852e-7932.03RUN and FYVE domain-containing protein 1 OS=Homo s... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3I7861.810e-10137.22RUN and FYVE domain-containing protein 2 isoform X... [more]
A0A1S3I7A03.486e-10137.46RUN and FYVE domain-containing protein 2 isoform X... [more]
A0A2R2MRA75.907e-10137.46RUN and FYVE domain-containing protein 2-like OS=L... [more]
A0A0B7A5851.372e-9635.40Uncharacterized protein (Fragment) OS=Arion vulgar... [more]
A0A0B7A5195.613e-9635.40Uncharacterized protein (Fragment) OS=Arion vulgar... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rufy14.066e-8131.59RUN and FYVE domain containing 1 [Source:NCBI gene... [more]
rufy27.545e-7432.77RUN and FYVE domain containing 2 [Source:ZFIN;Acc:... [more]
rufy23.943e-7332.77RUN and FYVE domain containing 2 [Source:ZFIN;Acc:... [more]
rufy36.293e-7030.63RUN and FYVE domain containing 3 [Source:NCBI gene... [more]
rufy39.861e-7030.47RUN and FYVE domain containing 3 [Source:NCBI gene... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rufy35.991e-3131.70RUN and FYVE domain containing 3 [Source:ZFIN;Acc:... [more]
ENSPMAT00000001934.15.092e-2641.51pep scaffold:Pmarinus_7.0:GL488632:1056:3278:1 gen... [more]
eea11.151e-1851.72early endosome antigen 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
ENSPMAT00000005437.17.740e-1131.63pep scaffold:Pmarinus_7.0:GL486528:10206:16522:1 g... [more]
ankfy14.568e-1040.30ankyrin repeat and FYVE domain containing 1 [Sourc... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
VPS273.415e-1338.46Endosomal protein that forms a complex with Hse1p;... [more]
FAB13.424e-938.711-phosphatidylinositol-3-phosphate 5-kinase; vacuo... [more]
PIB14.068e-933.77RING-type ubiquitin ligase of the endosomal and va... [more]
PIB23.245e-747.22Protein of unknown function; contains FYVE domain;... [more]
PEP72.685e-647.50Adaptor protein involved in vesicle-mediated vacuo... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO449692.042e-3932.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449687.959e-2331.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO385012.003e-1431.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO446152.154e-1439.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO481842.204e-1238.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rufy24.308e-9234.47RUN and FYVE domain containing 2 [Source:NCBI gene... [more]
rufy13.816e-8333.01RUN and FYVE domain-containing protein 1 [Source:N... [more]
rufy12.770e-7532.78RUN and FYVE domain-containing protein 1 [Source:N... [more]
rufy36.850e-5232.24RUN and FYVE domain containing 3 [Source:NCBI gene... [more]
rufy32.952e-5132.00RUN and FYVE domain containing 3 [Source:NCBI gene... [more]
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BLAST of RUN and FYVE domain-containing protein 2-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000050873.10.000e+099.84SMESG000050873.1[more]
SMESG000008512.19.383e-1753.45SMESG000008512.1[more]
SMESG000069357.11.982e-1348.33SMESG000069357.1[more]
SMESG000051464.11.193e-935.71SMESG000051464.1[more]
SMESG000051464.11.289e-935.71SMESG000051464.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016150 ID=SMED30016150|Name=RUN and FYVE domain-containing protein 2-like|organism=Schmidtea mediterranea sexual|type=transcript|length=2285bp
ATTTAATTATTTTAATACTTTTTTTAATAATTAGAATAATGTTTTATACT
TTGAGATGTATTAACAATTTTTGAAAATATTAGTTTAAAATATAATTTTT
TCTCAAAATTGATTTTTACACTACTTTGAAGAATTTATTATATTTCTGTA
AATTATTTTAAAAGTTATTTAATTATAATATAAATGGAATTTACAAAAGA
AAATAATGAAATTTTAAGTGATTTTGAAATCGAGCGTTGTAACATCATTC
ATTTAACTAAATTAGTCGTCAAAGATATTTTAAGAGTAGCAGTCAAGACC
AATCGACAATTAGATGAAGATAATCCATTAATAATCCAGTTATTGCGTGT
ATTGGAAAGTATCGTAAAACATGGCTTAAAACCGAAAAAAATTCTAAATA
GTGTAACGATTGCTGGATTTAACAATCTAGATCCATGGCCGGTTATTTGT
GATTTATTGAAAAAACAAACTAGTGTAGAAATAATAGAAACTATCCAACA
AATGGGAATTAAATCGGGATTAGGTCGGTTTAGAGTTTGGTTGAAAATGA
CTTTGATGCAAAAACAATTGGGTAATTATTTCCACATTATTACAAGTCAA
GGGAGAAAATTAGAACTATATTATTATCCTTCTGCAGTTTTATTAGAAGA
AAGTGGCGTTGAAATTGCTGGATTTTTAGTTGGTTTATCTGTCATTGATT
GCAATTTTTTAAAGCTCCGAGATACCACCATTGATTCAGATATAAATATT
GGTCCTCTCAATTACAGCTCATATATGAAAAGAGACTTTGATGAAGTCGA
CAGTTTATCAGTATCAGAAGTAAACAATACTGATGAAACCATAAAAAGTT
TACTTGACCAAAAAAATTACACTGAAGAATTAAATTCTGTTCTCCAATTG
AAACTGACGAATTTACAGAATGGTTATAATTTATTGGAAAGAGAAGTTGC
CAACGGGAAAATCATGTTGGCCGACGGTACGAATCGTCAATTGAATTTAG
TAGAGGAATTGAATAAATTGAAAGGAGAAAATAATTATCTCAAGAGTCTT
TATGATCATAAAAATAAACTCATGCAAGACGATATTCAAGTTGAAAGAAG
CACATATCAGACATCTCGCCAGGAATTGAATATACTTAATATTGAACTTG
AAAAGAAATTAAAAGAAGAAGTTCAAATCAGATTGGATACCGACAAGTCA
TTGCAATCGGAAGTGCAACGTCGAACTGACATTGAAATAGGGATGAGTAC
TCTGGAAAAACAAGTTCAAGAAAAACAACAAACTATTTTGAGCCTCAGAA
AGCAAATGGAACAATTAAAAGCAATAAACATGGAATTAAATAAAGATTTT
AAGGAAAAACAAACAGTTTATGAACACAAATCAGTGCTAGTGGATAAATT
AGAAGAAAAAACAGCAGGAATGGCGAATATTATTGACCAAATGGATCAAA
GAATAAAAAAATTTGTATCAGAAAAATTGATTTCGGATCAGATTATATTG
GAATCGAAAACGAAGTTAGAAGAAAAAGAGAAAACATGTTCCCTTAAAGA
AGAGGAAATCGACGAGTTGTTTGAGAAAATTAATGATCTTATAAAGGAGG
TTGATTCTCTAAAGACTGAAAAGGAAGATTTGTCAGAGAAATTATCCAAG
ATGAATTTACAATTGAATTTTGTTGAAAAAGAACTCTCACTTTCAAAGAA
ACGTATATATGATCAATCTGAAGCATTGGAAGATATGGCTAAATTATTAG
AAAATAGTAAATTGGAAACTGACGGCTTGCGAGAAATGCAAGCAAGTTTT
CAGGAAGCTAGATGGACAGATGATAAAGAAGTTAATCAGTGTATTCAATG
TGCAAAGCCATTTAATGTTAGCAGGAGAAAGCACCATTGCCGGCGGTGCG
GAGGGGTATATTGTCACGAATGTTCTAGTAATCGAATGTCGTTAGCGAGC
TCGTCGAAACCGATGCGAGTTTGCGATACTTGCCATAATGCGCTGTTGAA
AAGTTACACCTCGATGACATCGAGAAGTGATAGCGATGCCTCGTGAAACT
GATGGACAAATTACTGTGATTATTAAATTTCTGGCATAAAGCTTTGTGAT
TTGTGACTTTCTTGAGAGTTGATTGGTGGAAATTGTGTACATCTTTCATA
AGTGACATTCAAACTTATTTTACCCAAATCAAACTGAATAATTAATTGAC
CGGCCTTTAATTATTCGCTTTATTCACCGTTTTTATAAAATTTTACAGAA
ATTTGTAATAAATTTTTGTATTTCGTCAAAAAAAA
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protein sequence of SMED30016150-orf-1

>SMED30016150-orf-1 ID=SMED30016150-orf-1|Name=SMED30016150-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=621bp
MEFTKENNEILSDFEIERCNIIHLTKLVVKDILRVAVKTNRQLDEDNPLI
IQLLRVLESIVKHGLKPKKILNSVTIAGFNNLDPWPVICDLLKKQTSVEI
IETIQQMGIKSGLGRFRVWLKMTLMQKQLGNYFHIITSQGRKLELYYYPS
AVLLEESGVEIAGFLVGLSVIDCNFLKLRDTTIDSDINIGPLNYSSYMKR
DFDEVDSLSVSEVNNTDETIKSLLDQKNYTEELNSVLQLKLTNLQNGYNL
LEREVANGKIMLADGTNRQLNLVEELNKLKGENNYLKSLYDHKNKLMQDD
IQVERSTYQTSRQELNILNIELEKKLKEEVQIRLDTDKSLQSEVQRRTDI
EIGMSTLEKQVQEKQQTILSLRKQMEQLKAINMELNKDFKEKQTVYEHKS
VLVDKLEEKTAGMANIIDQMDQRIKKFVSEKLISDQIILESKTKLEEKEK
TCSLKEEEIDELFEKINDLIKEVDSLKTEKEDLSEKLSKMNLQLNFVEKE
LSLSKKRIYDQSEALEDMAKLLENSKLETDGLREMQASFQEARWTDDKEV
NQCIQCAKPFNVSRRKHHCRRCGGVYCHECSSNRMSLASSSKPMRVCDTC
HNALLKSYTSMTSRSDSDAS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000043dorsal ventral margin of the whole animal
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR037213Run_dom_sf
IPR004012Run_dom
IPR000306Znf_FYVE
IPR013083Znf_RING/FYVE/PHD
IPR017455Znf_FYVE-rel
IPR011011Znf_FYVE_PHD
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0008289lipid binding
GO:0008565protein transporter activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005768endosome
GO:0005829cytosol
GO:0016020membrane
GO:0016607nuclear speck
GO:0031901early endosome membrane
GO:0043231intracellular membrane-bounded organelle
Vocabulary: biological process
TermDefinition
GO:0006661phosphatidylinositol biosynthetic process
GO:0006810transport
GO:0006897endocytosis
GO:0015031protein transport
GO:0030100regulation of endocytosis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 234..254
NoneNo IPR availableCOILSCoilCoilcoord: 354..388
NoneNo IPR availableCOILSCoilCoilcoord: 445..500
NoneNo IPR availableCOILSCoilCoilcoord: 308..328
NoneNo IPR availablePANTHERPTHR23164EARLY ENDOSOME ANTIGEN 1coord: 14..612
NoneNo IPR availablePANTHERPTHR23164:SF22RUN AND FYVE DOMAIN CONTAINING 1coord: 14..612
NoneNo IPR availableCDDcd15721FYVE_RUFY1_likecoord: 544..601
e-value: 6.13444E-35
score: 124.032
IPR000306FYVE zinc fingerSMARTSM00064fyve_4coord: 539..606
e-value: 7.8E-22
score: 88.5
IPR000306FYVE zinc fingerPFAMPF01363FYVEcoord: 543..604
e-value: 1.5E-19
score: 69.9
IPR004012RUN domainSMARTSM00593893paper3coord: 116..178
e-value: 9.3E-9
score: 45.1
IPR004012RUN domainPFAMPF02759RUNcoord: 52..175
e-value: 1.2E-13
score: 51.2
IPR004012RUN domainPROSITEPS50826RUNcoord: 44..181
score: 23.541
IPR037213RUN domain superfamilyGENE3DG3DSA:1.20.58.900coord: 9..189
e-value: 8.2E-39
score: 135.0
IPR037213RUN domain superfamilySUPERFAMILYSSF140741RUN domain-likecoord: 17..176
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 532..613
e-value: 2.2E-25
score: 90.2
IPR017455Zinc finger, FYVE-relatedPROSITEPS50178ZF_FYVEcoord: 547..605
score: 13.449
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 543..611