methylmalonyl-CoA mutase, mitochondrial

Overview
Namemethylmalonyl-CoA mutase, mitochondrial
Smed IDSMED30016140
Length (bp)2419
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of methylmalonyl-CoA mutase, mitochondrial (SMED30016140) t-SNE clustered cells

Violin plots show distribution of expression levels for methylmalonyl-CoA mutase, mitochondrial (SMED30016140) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of methylmalonyl-CoA mutase, mitochondrial (SMED30016140) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for methylmalonyl-CoA mutase, mitochondrial (SMED30016140) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30016140

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30016140h1SMcG0019749 dd_Smed_v4_2255_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30016140h1SMcG0019749 dd_Smed_v4_2255_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30016140h1SMcG0019749 dd_Smed_v4_2255_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30016140h1SMcG0019749 dd_Smed_v4_2255_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30016140h1SMcG0019749 dd_Smed_v4_2255_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30016140h1SMcG0019749 dd_Smed_v4_2255_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30016140h1SMcG0019749 dd_Smed_v4_2255_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016140h1SMcG0019749 Contig16878newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016140h1SMcG0019749 Contig16878uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Human
Match: MMUT (methylmalonyl-CoA mutase [Source:HGNC Symbol;Acc:HGNC:7526])

HSP 1 Score: 1073.54 bits (2775), Expect = 0.000e+0
Identity = 530/713 (74.33%), Postives = 605/713 (84.85%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            Q PLH EW  LAKKQLKG +P + L WHT EGI IKP+Y+K+DT  L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+P+LA F+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSMKII DIFEYTAKHMPKFNSISISGYHMQEAGA+AILE+AYT+ADGLEY RTGL+AGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA L++  F  K+ KSLLLRAH QTSGWSLTEQDPYNNI+RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LT ++Y  A+K+I+E+E MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  + V+VL IDNT VR  QI K+K ++ SRD   A+  L  L EC  SG GN+L +A+DA+RARCTVGEITDA+  V+G H A  R+VSGAY+ EFG+ KEI++ IK+V  F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +G+S+LAAGH TLVP+LI EL + GR       DI+V+ GGVIPPQDYEFL + GVS +FGPGTRIP AA++V+D I K
Sbjct:   36 QQPLHPEWAALAKKQLKGKNP-EDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLGRP------DILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEK 741
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Celegans
Match: mmcm-1 (Probable methylmalonyl-CoA mutase, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:Q23381])

HSP 1 Score: 1032.32 bits (2668), Expect = 0.000e+0
Identity = 507/718 (70.61%), Postives = 608/718 (84.68%), Query Frame = 1 
Query:  112 TQLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDT---TKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKN 2256
            T+ P+ ++W  +AKK +KG +    LTW+T EGI IKP+Y + D     + + E+PG++PFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYK+NIKAG QGLSVAFDLATHRGYDSDNPRVFGDVGMAGVA+DSVEDM++LF+GI L+ +S SMTMNGAV+P+LAM+VVA EE G  +++L GTIQNDILKEFMVRNTYI+PPEPSM+IIGDIF YT++ MPKFNSISISGYHMQEAGA+A+LEMA+TIADG++YC TGL AGL ID FAPRLSFFWG+ MNFYMEIAKMRAARR+WA L+K +F  K  KS++LR HSQTSGWSLTEQDPYNNI+RTTIEAMA+VFGGTQSLHTN+FDEALGLPTKFSARIARNTQIIIQEE+GI  VADPW GS+MMESLT+EIY +A+ +I E++ +GGMAKAVA G+ KLKIEE AAK+QA ID+GK+VIVGVNKYRL++ ++V+VL IDN KVRE Q AK+  +R +RD  KAQ  L  + E  + G+GNL+++AI+AARARCTVGEI+DAM  V+ RH AV RLVSGAYKSEFG+  E+S V+++V+ F   +GR+PRI++AK+GQDGHDRG KVIATGF+DLGFDVDVGPLF TP EA +QAVDADVHVIG SSLAAGH+TL+PQLI ELK  GR       DI+VVAGGVIPPQDY+ L  AGV+ +FGPGTR+P  A ++++ +  N
Sbjct:   24 TRSPIDQKWAAMAKKAMKGRE-ADTLTWNTPEGIPIKPLYLRSDRDCDAQRSVELPGQFPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKENIKAGQQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAVDSVEDMRQLFDGINLEKMSVSMTMNGAVVPVLAMYVVAAEEAGVSRKLLAGTIQNDILKEFMVRNTYIYPPEPSMRIIGDIFAYTSREMPKFNSISISGYHMQEAGADAVLEMAFTIADGIQYCETGLNAGLTIDAFAPRLSFFWGISMNFYMEIAKMRAARRLWANLIKERFSPKSDKSMMLRTHSQTSGWSLTEQDPYNNIIRTTIEAMASVFGGTQSLHTNSFDEALGLPTKFSARIARNTQIIIQEESGICNVADPWGGSYMMESLTDEIYEKALAVIKEIDELGGMAKAVASGMTKLKIEEAAAKKQARIDAGKDVIVGVNKYRLDHEQQVEVLKIDNAKVREEQCAKLNHIRATRDAEKAQKALDAITEGAR-GNGNLMELAIEAARARCTVGEISDAMEKVFNRHAAVNRLVSGAYKSEFGETSEMSQVLERVKSFADRDGRQPRIMVAKMGQDGHDRGAKVIATGFADLGFDVDVGPLFQTPLEAAQQAVDADVHVIGASSLAAGHLTLIPQLIGELKKLGRP------DILVVAGGVIPPQDYKELYDAGVALVFGPGTRLPACANQILEKLEAN 733
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Zebrafish
Match: mut (methylmalonyl CoA mutase [Source:ZFIN;Acc:ZDB-GENE-010430-3])

HSP 1 Score: 1060.06 bits (2740), Expect = 0.000e+0
Identity = 527/723 (72.89%), Postives = 607/723 (83.96%), Query Frame = 1 
Query:  106 YSTQLPL------HKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKN 2256
            +ST +PL      H+ W  LAKKQLKG +P + L W T EGI IKPVYT+ DT K  +E+PG +PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+PILAMF+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSM  I DIF YT+K+MPKFNSISISGYH+QEAGA+AILE+AYTIA+GLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAK+RAARR+WA L+K KF  K+ KSLLLR H QTSGWSLTEQDPYNN++RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME+LT ++Y  A+K I E+E MGGMA+AVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKYRLE  E VDVL IDNT VR  QI K++ +R+SRD   A+  L  +E+C ++  GNLL++A++AARARC+VGEITDAM +V+G H A  R+VSGAY+SEFG+ +EI+    +V  F K EGR PR+L+AK+GQDGHDRG KVIATGF+DLGFDVDVGPLF TP E  +QAVDADVH +GVS+LAAGH TLVP+LI EL+N  R       DI+V+ GGVIPPQDYEFL  +GVS IFGPGTRIP AA++V+D+I K+
Sbjct:   34 FSTAVPLRDEVKIHEAWAALAKKQLKGKNP-EDLIWKTPEGISIKPVYTQTDTAKAPDELPGVFPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDTKLLFDGIPLEKMSVSMTMNGAVIPILAMFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMHAIADIFAYTSKNMPKFNSISISGYHIQEAGADAILELAYTIANGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKLRAARRLWATLIKEKFQPKNSKSLLLRTHCQTSGWSLTEQDPYNNVIRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMEALTNDVYNSALKFITEIEDMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYRLEKEESVDVLAIDNTAVRNKQIEKLQKVRESRDAEAAKRCLAAIEQCARTRDGNLLELAVEAARARCSVGEITDAMKSVFGEHKASTRMVSGAYRSEFGEHEEIALAHNRVVQFKKHEGRNPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDVGPLFQTPLEVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELRNLNRP------DIMVICGGVIPPQDYEFLYASGVSCIFGPGTRIPKAAVEVLDSIEKS 749
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Xenopus
Match: camsap3 (calmodulin regulated spectrin associated protein family member 3 [Source:Xenbase;Acc:XB-GENE-5845672])

HSP 1 Score: 1077 bits (2784), Expect = 0.000e+0
Identity = 529/708 (74.72%), Postives = 606/708 (85.59%), Query Frame = 1 
Query:  124 LHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAI 2247
            LH EW  LAKKQLKG DP + L WHT EGI IKP+YTK+DTT+L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VEDMK LF+GI L+ +S SMTMNGAV+PILAMF+V G EQG  +E LTGTIQNDILKEFMVRNTYIFPP PSM+II DIF+YT+++MPKFNSISISGYHMQEAGA+A+LE+AYT+ADGLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA+L++  F  KDKKSLLLRAH QTSGWSLTEQDPYNN++RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LTE++Y  A+K+I+EVE MGGMA+AVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  E V+VL IDNT VR  QI K++ ++ SRDN  AQ  L  + EC  +G GN+L +A++AA+ARCTVGEITDAM  V+G H A  R+VSGAY+ EFG+ +EIS  I +V+ F+  EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL  AGVS +FGPGTRIP AA++V+D I
Sbjct:  102 LHPEWAALAKKQLKGKDP-ESLRWHTPEGIVIKPLYTKRDTTELPEELPGVKPFTRGPYPTMYTHRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDMKMLFDGIPLEKMSVSMTMNGAVVPILAMFIVTGMEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPVPSMRIIADIFQYTSQNMPKFNSISISGYHMQEAGADAVLELAYTVADGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWADLIEKNFQPKDKKSLLLRAHCQTSGWSLTEQDPYNNVVRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTEDVYQAALKLINEVEEMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYKLEKEESVEVLAIDNTSVRNRQIEKLEKVKASRDNAAAQQCLSAITECAATGKGNILGLAVEAAQARCTVGEITDAMKKVFGEHKASDRMVSGAYRQEFGESEEISFSISRVQKFMDREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELSALGRP------DILVICGGVIPPQDYEFLYNAGVSSVFGPGTRIPKAAVQVIDDI 802
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Xenopus
Match: camsap3 (calmodulin regulated spectrin associated protein family member 3 [Source:Xenbase;Acc:XB-GENE-5845672])

HSP 1 Score: 1075.46 bits (2780), Expect = 0.000e+0
Identity = 529/708 (74.72%), Postives = 606/708 (85.59%), Query Frame = 1 
Query:  124 LHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAI 2247
            LH EW  LAKKQLKG DP + L WHT EGI IKP+YTK+DTT+L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VEDMK LF+GI L+ +S SMTMNGAV+PILAMF+V G EQG  +E LTGTIQNDILKEFMVRNTYIFPP PSM+II DIF+YT+++MPKFNSISISGYHMQEAGA+A+LE+AYT+ADGLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA+L++  F  KDKKSLLLRAH QTSGWSLTEQDPYNN++RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LTE++Y  A+K+I+EVE MGGMA+AVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  E V+VL IDNT VR  QI K++ ++ SRDN  AQ  L  + EC  +G GN+L +A++AA+ARCTVGEITDAM  V+G H A  R+VSGAY+ EFG+ +EIS  I +V+ F+  EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL  AGVS +FGPGTRIP AA++V+D I
Sbjct:   30 LHPEWAALAKKQLKGKDP-ESLRWHTPEGIVIKPLYTKRDTTELPEELPGVKPFTRGPYPTMYTHRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDMKMLFDGIPLEKMSVSMTMNGAVVPILAMFIVTGMEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPVPSMRIIADIFQYTSQNMPKFNSISISGYHMQEAGADAVLELAYTVADGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWADLIEKNFQPKDKKSLLLRAHCQTSGWSLTEQDPYNNVVRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTEDVYQAALKLINEVEEMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYKLEKEESVEVLAIDNTSVRNRQIEKLEKVKASRDNAAAQQCLSAITECAATGKGNILGLAVEAAQARCTVGEITDAMKKVFGEHKASDRMVSGAYRQEFGESEEISFSISRVQKFMDREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELSALGRP------DILVICGGVIPPQDYEFLYNAGVSSVFGPGTRIPKAAVQVIDDI 730
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Xenopus
Match: camsap3 (calmodulin regulated spectrin associated protein family member 3 [Source:Xenbase;Acc:XB-GENE-5845672])

HSP 1 Score: 1075.46 bits (2780), Expect = 0.000e+0
Identity = 529/708 (74.72%), Postives = 606/708 (85.59%), Query Frame = 1 
Query:  124 LHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAI 2247
            LH EW  LAKKQLKG DP + L WHT EGI IKP+YTK+DTT+L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VEDMK LF+GI L+ +S SMTMNGAV+PILAMF+V G EQG  +E LTGTIQNDILKEFMVRNTYIFPP PSM+II DIF+YT+++MPKFNSISISGYHMQEAGA+A+LE+AYT+ADGLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA+L++  F  KDKKSLLLRAH QTSGWSLTEQDPYNN++RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LTE++Y  A+K+I+EVE MGGMA+AVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  E V+VL IDNT VR  QI K++ ++ SRDN  AQ  L  + EC  +G GN+L +A++AA+ARCTVGEITDAM  V+G H A  R+VSGAY+ EFG+ +EIS  I +V+ F+  EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL  AGVS +FGPGTRIP AA++V+D I
Sbjct:   36 LHPEWAALAKKQLKGKDP-ESLRWHTPEGIVIKPLYTKRDTTELPEELPGVKPFTRGPYPTMYTHRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDMKMLFDGIPLEKMSVSMTMNGAVVPILAMFIVTGMEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPVPSMRIIADIFQYTSQNMPKFNSISISGYHMQEAGADAVLELAYTVADGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWADLIEKNFQPKDKKSLLLRAHCQTSGWSLTEQDPYNNVVRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTEDVYQAALKLINEVEEMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYKLEKEESVEVLAIDNTSVRNRQIEKLEKVKASRDNAAAQQCLSAITECAATGKGNILGLAVEAAQARCTVGEITDAMKKVFGEHKASDRMVSGAYRQEFGESEEISFSISRVQKFMDREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELSALGRP------DILVICGGVIPPQDYEFLYNAGVSSVFGPGTRIPKAAVQVIDDI 736
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Xenopus
Match: camsap3 (calmodulin regulated spectrin associated protein family member 3 [Source:Xenbase;Acc:XB-GENE-5845672])

HSP 1 Score: 1075.46 bits (2780), Expect = 0.000e+0
Identity = 529/708 (74.72%), Postives = 606/708 (85.59%), Query Frame = 1 
Query:  124 LHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAI 2247
            LH EW  LAKKQLKG DP + L WHT EGI IKP+YTK+DTT+L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VEDMK LF+GI L+ +S SMTMNGAV+PILAMF+V G EQG  +E LTGTIQNDILKEFMVRNTYIFPP PSM+II DIF+YT+++MPKFNSISISGYHMQEAGA+A+LE+AYT+ADGLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA+L++  F  KDKKSLLLRAH QTSGWSLTEQDPYNN++RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LTE++Y  A+K+I+EVE MGGMA+AVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  E V+VL IDNT VR  QI K++ ++ SRDN  AQ  L  + EC  +G GN+L +A++AA+ARCTVGEITDAM  V+G H A  R+VSGAY+ EFG+ +EIS  I +V+ F+  EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL  AGVS +FGPGTRIP AA++V+D I
Sbjct:   32 LHPEWAALAKKQLKGKDP-ESLRWHTPEGIVIKPLYTKRDTTELPEELPGVKPFTRGPYPTMYTHRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDMKMLFDGIPLEKMSVSMTMNGAVVPILAMFIVTGMEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPVPSMRIIADIFQYTSQNMPKFNSISISGYHMQEAGADAVLELAYTVADGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWADLIEKNFQPKDKKSLLLRAHCQTSGWSLTEQDPYNNVVRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTEDVYQAALKLINEVEEMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYKLEKEESVEVLAIDNTSVRNRQIEKLEKVKASRDNAAAQQCLSAITECAATGKGNILGLAVEAAQARCTVGEITDAMKKVFGEHKASDRMVSGAYRQEFGESEEISFSISRVQKFMDREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELSALGRP------DILVICGGVIPPQDYEFLYNAGVSSVFGPGTRIPKAAVQVIDDI 732
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Xenopus
Match: camsap3 (calmodulin regulated spectrin associated protein family member 3 [Source:Xenbase;Acc:XB-GENE-5845672])

HSP 1 Score: 1075.08 bits (2779), Expect = 0.000e+0
Identity = 529/708 (74.72%), Postives = 606/708 (85.59%), Query Frame = 1 
Query:  124 LHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAI 2247
            LH EW  LAKKQLKG DP + L WHT EGI IKP+YTK+DTT+L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VEDMK LF+GI L+ +S SMTMNGAV+PILAMF+V G EQG  +E LTGTIQNDILKEFMVRNTYIFPP PSM+II DIF+YT+++MPKFNSISISGYHMQEAGA+A+LE+AYT+ADGLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA+L++  F  KDKKSLLLRAH QTSGWSLTEQDPYNN++RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LTE++Y  A+K+I+EVE MGGMA+AVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  E V+VL IDNT VR  QI K++ ++ SRDN  AQ  L  + EC  +G GN+L +A++AA+ARCTVGEITDAM  V+G H A  R+VSGAY+ EFG+ +EIS  I +V+ F+  EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL  AGVS +FGPGTRIP AA++V+D I
Sbjct:   34 LHPEWAALAKKQLKGKDP-ESLRWHTPEGIVIKPLYTKRDTTELPEELPGVKPFTRGPYPTMYTHRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDMKMLFDGIPLEKMSVSMTMNGAVVPILAMFIVTGMEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPVPSMRIIADIFQYTSQNMPKFNSISISGYHMQEAGADAVLELAYTVADGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWADLIEKNFQPKDKKSLLLRAHCQTSGWSLTEQDPYNNVVRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTEDVYQAALKLINEVEEMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYKLEKEESVEVLAIDNTSVRNRQIEKLEKVKASRDNAAAQQCLSAITECAATGKGNILGLAVEAAQARCTVGEITDAMKKVFGEHKASDRMVSGAYRQEFGESEEISFSISRVQKFMDREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELSALGRP------DILVICGGVIPPQDYEFLYNAGVSSVFGPGTRIPKAAVQVIDDI 734
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Mouse
Match: Mmut (methylmalonyl-Coenzyme A mutase [Source:MGI Symbol;Acc:MGI:97239])

HSP 1 Score: 1077 bits (2784), Expect = 0.000e+0
Identity = 532/713 (74.61%), Postives = 605/713 (84.85%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            Q PLH EW  LAKKQLKG +P + L WHT EGI IKP+Y++ DT  L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+P+LA F+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSMKII DIF+YTA+HMPKFNSISISGYHMQEAGA+AILE+AYTIADGLEYCRTGL+AGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA L++  F  K+ KSLLLRAH QTSGWSLTEQDPYNNI+RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MMESLT ++Y  A+K+I EVE MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  + V+VL IDNT VR+ QI K+K ++ SRD   A+  L  L +C  SG GN+L +A+DAARARCTVGEITDA+  V+G H A  R+VSGAY+ EFG+ KEI++ IK+V  F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL + GVS +FGPGTRIP AA++V+D I K
Sbjct:   34 QQPLHPEWAVLAKKQLKGKNP-EDLIWHTPEGISIKPLYSRADTLDLPEELPGVKPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAQHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYEAALKLIYEVEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDSVEVLAIDNTSVRKKQIEKLKKIKSSRDQALAEQCLSALTQCAASGDGNILALAVDAARARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELTALGRP------DILVMCGGVIPPQDYEFLYEVGVSNVFGPGTRIPRAAVQVLDDIEK 739
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Mouse
Match: Mmut (methylmalonyl-Coenzyme A mutase [Source:MGI Symbol;Acc:MGI:97239])

HSP 1 Score: 235.343 bits (599), Expect = 3.192e-72
Identity = 111/169 (65.68%), Postives = 136/169 (80.47%), Query Frame = 1 
Query: 1663 IAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFL 2169
            +A+DAARARCTVGEITDA+  V+G H A  R+VSGAY+ EFG+ KEI++ IK+V  F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQ +  L
Sbjct:    3 LAVDAARARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELTALGRP------DILVMCGGVIPPQVFFLL 165
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. UniProt/SwissProt
Match: sp|Q9GK13|MUTA_BOVIN (Methylmalonyl-CoA mutase, mitochondrial OS=Bos taurus OX=9913 GN=MMUT PE=2 SV=1)

HSP 1 Score: 1080.09 bits (2792), Expect = 0.000e+0
Identity = 535/713 (75.04%), Postives = 603/713 (84.57%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            Q PLH EW  LAKKQLKG +P + L WHT EGI IKP+Y+K+DT  L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDLATHRGYDSDNPR+ GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+P+LA F+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSMKII DIF+YTAKHMPKFNSISISGYHMQEAGA+AILE+AYTIADGLEYCRTGL+AGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA L++     K+ KSLLLRAH QTSGWSLTEQDPYNNI+RTTIEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MMESLT +IY  A+K+I+E+E MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  E VDVL IDNT VR  QI K+K ++ SRD   A+  L  L  C  SG GN+L +A+DA RARCTVGEIT AM  V+G H A  R+VSGAY+ EFG+ KEI+  IK+VE F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL + GVS +FGPGTRIP AA++V+D I K
Sbjct:   36 QQPLHPEWAALAKKQLKGKNP-EDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRLRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAKHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMLQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIIRTTIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDIYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEESVDVLAIDNTSVRNKQIEKLKKVKSSRDQALAERCLDALTACAASGDGNILALAVDATRARCTVGEITYAMKKVFGEHKANDRMVSGAYRQEFGESKEIAFAIKRVEKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHTVGVSTLAAGHKTLVPELIKELNALGRP------DILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEK 741
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. UniProt/SwissProt
Match: sp|P16332|MUTA_MOUSE (Methylmalonyl-CoA mutase, mitochondrial OS=Mus musculus OX=10090 GN=Mmut PE=1 SV=2)

HSP 1 Score: 1077 bits (2784), Expect = 0.000e+0
Identity = 532/713 (74.61%), Postives = 605/713 (84.85%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            Q PLH EW  LAKKQLKG +P + L WHT EGI IKP+Y++ DT  L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+P+LA F+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSMKII DIF+YTA+HMPKFNSISISGYHMQEAGA+AILE+AYTIADGLEYCRTGL+AGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA L++  F  K+ KSLLLRAH QTSGWSLTEQDPYNNI+RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MMESLT ++Y  A+K+I EVE MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  + V+VL IDNT VR+ QI K+K ++ SRD   A+  L  L +C  SG GN+L +A+DAARARCTVGEITDA+  V+G H A  R+VSGAY+ EFG+ KEI++ IK+V  F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL   GR       DI+V+ GGVIPPQDYEFL + GVS +FGPGTRIP AA++V+D I K
Sbjct:   34 QQPLHPEWAVLAKKQLKGKNP-EDLIWHTPEGISIKPLYSRADTLDLPEELPGVKPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAQHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYEAALKLIYEVEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDSVEVLAIDNTSVRKKQIEKLKKIKSSRDQALAEQCLSALTQCAASGDGNILALAVDAARARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELTALGRP------DILVMCGGVIPPQDYEFLYEVGVSNVFGPGTRIPRAAVQVLDDIEK 739
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. UniProt/SwissProt
Match: sp|Q8HXX1|MUTA_MACFA (Methylmalonyl-CoA mutase, mitochondrial OS=Macaca fascicularis OX=9541 GN=MMUT PE=2 SV=1)

HSP 1 Score: 1074.31 bits (2777), Expect = 0.000e+0
Identity = 529/713 (74.19%), Postives = 606/713 (84.99%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            Q PLH EW  LAK+QLKG +P + L WHT EGI IKP+Y+K+DTT L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+P+LA F+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSMKII DIF+YT+KHMPKFNSISISGYHMQEAGA+AILE+AYT+ADGLEY RTGL+AGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA L++  F  K  KSLLLRAH QTSGWSLTEQDPYNNI+RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MMESLT ++Y  A+K+I+E+E MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  + V+VL IDNT VR  QI K++ ++ SRD   A+  L  L EC  SG GN+L +A+DA+RARCTVGEITDA+  V+G H A  R+VSGAY+ EFG+ KEI++ IK+V  F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL + GR       DI+V+ GGVIPPQDYEFL + GVS +FGPGTRIP AA++V+D I K
Sbjct:   36 QQPLHPEWAALAKRQLKGKNP-EDLIWHTPEGISIKPLYSKRDTTDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTSKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKSSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLQKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRP------DILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEK 741
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. UniProt/SwissProt
Match: sp|P22033|MUTA_HUMAN (Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4)

HSP 1 Score: 1073.54 bits (2775), Expect = 0.000e+0
Identity = 530/713 (74.33%), Postives = 605/713 (84.85%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            Q PLH EW  LAKKQLKG +P + L WHT EGI IKP+Y+K+DT  L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+P+LA F+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSMKII DIFEYTAKHMPKFNSISISGYHMQEAGA+AILE+AYT+ADGLEY RTGL+AGL IDEFAPRLSFFWG+GMNFYMEIAKMRA RR+WA L++  F  K+ KSLLLRAH QTSGWSLTEQDPYNNI+RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LT ++Y  A+K+I+E+E MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  + V+VL IDNT VR  QI K+K ++ SRD   A+  L  L EC  SG GN+L +A+DA+RARCTVGEITDA+  V+G H A  R+VSGAY+ EFG+ KEI++ IK+V  F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +G+S+LAAGH TLVP+LI EL + GR       DI+V+ GGVIPPQDYEFL + GVS +FGPGTRIP AA++V+D I K
Sbjct:   36 QQPLHPEWAALAKKQLKGKNP-EDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLGRP------DILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEK 741
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. UniProt/SwissProt
Match: sp|Q5RFN2|MUTA_PONAB (Methylmalonyl-CoA mutase, mitochondrial OS=Pongo abelii OX=9601 GN=MMUT PE=2 SV=1)

HSP 1 Score: 1072.77 bits (2773), Expect = 0.000e+0
Identity = 530/713 (74.33%), Postives = 604/713 (84.71%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            Q PLH EW  LAKKQLKG +P + L WHT EGI IKP+Y+K+DT  L EE+PG  PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVAID+VED K LF+GI L+ +S SMTMNGAV+P+LA F+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSMKII DIFEYTAKHMPKFNSISISGYHMQEAGA+AILE+AYT+ADGLEY RTGL+AGL IDEFAPRLSFFWG+GMNFYMEI KMRA RR+WA L++  F  K+ KSLLLRAH QTSGWSLTEQDPYNNI+RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME LT ++Y  A+K+I+E+E MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKY+LE  + V+VL IDNT VR  QI K+K ++ SRD   A+  L  L EC  SG GN+L +A+DA+RARCTVGEITDA+  V+G H A  R+VSGAY+ EFG+ KEI++ IK+V  F++ EGRRPR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVH +GVS+LAAGH TLVP+LI EL + GR       DI+V+ GGVIPPQDYEFL + GVS +FGPGTRIP AA++V+D I K
Sbjct:   36 QQPLHPEWAALAKKQLKGKNP-EDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEITKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRP------DILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEK 741
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. TrEMBL
Match: A0A1S3HQ43 (methylmalonyl-CoA mutase, mitochondrial OS=Lingula unguis OX=7574 GN=LOC106156449 PE=4 SV=1)

HSP 1 Score: 1126.69 bits (2913), Expect = 0.000e+0
Identity = 551/723 (76.21%), Postives = 633/723 (87.55%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKNQSGHGNKKQ 2283
            Q PLH EW ELAKKQLKG DP++ L WHT EGID+KP+YTKQDT ++ +E+PGK+P+TRGPYPTMY QRPWTIRQYAGFSTVEESNKFY++NI AG QGLSVAFDL THRGYDSDNPR  GDVGMAGVAIDSVED K LF+GI L  ISTSMTMNGAVLPILAM+VV+ EEQG KQE LTGTIQNDILKEFMVRNTYIFPPEPSMK I DIF YTA +MPKFNSISISGYHMQEAGA+A+LEMA+TIADGLEYCRTGLKAGLHIDEFAPRLSFFWG+GMNF MEIAK+RAARR+WA L+K  FD+K++KSLLLR H QTSGWSLTEQDPYNNI+RTT+EAMAAVFGGTQSLHTN+FDEALGLPTKFSARIARNTQII+QEE+GI K+ DPW GS++ME+LT+E+Y +A+ +I EVE MGGMAKAVA G+PKL+IEECAA+RQA IDSG+E IVGVNKYRL NP+ V+VL IDN +V E Q+A++K +R++RDNNK Q  L+ + ECCKSG GNL+ ++IDAARAR TVGEIT AM  V+GRHVA  R+VSGAYK+E+G++ EI+ VIKKVE+F+  EGRRPRILIAK+GQDGHDRGGKVIATGF+D+GFDVD+GPLF+TPKEA +QA+DADVHV+GVSSLAAGH TLVP+LI  L + GR       DIVVV GGVIPPQDY+FL + GVS +FGPGTRIPDAAIKV+D II NQ    NK+Q
Sbjct:   31 QEPLHPEWRELAKKQLKGKDPQETLIWHTPEGIDVKPLYTKQDTARMVDELPGKFPYTRGPYPTMYAQRPWTIRQYAGFSTVEESNKFYRENIAAGQQGLSVAFDLPTHRGYDSDNPRASGDVGMAGVAIDSVEDTKLLFDGIPLGKISTSMTMNGAVLPILAMYVVSAEEQGVKQEQLTGTIQNDILKEFMVRNTYIFPPEPSMKSIADIFSYTAHNMPKFNSISISGYHMQEAGADAVLEMAFTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGIGMNFMMEIAKLRAARRLWANLIKDHFDAKNQKSLLLRCHCQTSGWSLTEQDPYNNIIRTTVEAMAAVFGGTQSLHTNSFDEALGLPTKFSARIARNTQIILQEESGIPKIVDPWGGSYVMEALTDELYDKALSVIQEVEEMGGMAKAVAAGMPKLRIEECAARRQARIDSGQEAIVGVNKYRLPNPDTVEVLMIDNKEVLEKQLARLKMVRETRDNNKVQETLQAITECCKSGDGNLMALSIDAARARATVGEITSAMEEVFGRHVATDRMVSGAYKTEYGENDEITHVIKKVEEFVSQEGRRPRILIAKVGQDGHDRGGKVIATGFADMGFDVDIGPLFATPKEAAQQAIDADVHVVGVSSLAAGHRTLVPELIQCLADMGRP------DIVVVTGGVIPPQDYDFLFEVGVSSVFGPGTRIPDAAIKVLDDIISNQ----NKRQ 743
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. TrEMBL
Match: V4AHG9 (B12-binding domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_227052 PE=4 SV=1)

HSP 1 Score: 1108.59 bits (2866), Expect = 0.000e+0
Identity = 538/717 (75.03%), Postives = 625/717 (87.17%), Query Frame = 1 
Query:  106 YSTQLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKN 2256
            YS++ P+  EW E AKK+LKG D ++ LTW T EGI+IKPVYT+ DT+ + +EIPGKYP+TRGPY TMYT RPWTIRQYAGFSTVEESNKFY++NI AG QGLSVAFDLATHRGYDSDN RV GDVGMAGVAIDSVED   LF+GI L  ISTSMTMNGAVLPI+AM++V+ EEQG KQ  L GTIQNDILKEFMVRNTYIFPPEPSMKIIGDIF YTAK+MPKFNSISISGYHMQEAGA+A+LE+A+TIADGL+Y RTGL++GL ID+FAPRLSFFWG+GM FYMEIAK+RAAR++WAEL+K KF   +KKSLLLRAH QTSGWSLTEQDPYNNI+RT IE MAAVFGGTQSLHTN+FDEALGLPTKFSARIARNTQII+QEE+G+ KVADPW GS MME LT++IY  A  +I+E+E MGGMAKAVA G+PKL+IEECAA+RQA IDSG+EVIVGVNKYRL++ E VDVL +DNT VRESQIA++K LR++RD+NK + +L  + ECCK+  GNLL+++I+AARARCTVGEITDAM  V+ RH A GRLVSGAYK+EFGD  EI+ V K++E F++ EGRRPRIL+AK+GQDGHDRGGKVIATGF+D+GFDVD+GPLF+TPKEA +QAVDADVHV+GVSSLAAGH +L+PQL+ ELKN GRS      DI+VVAGGVIPPQDY+FL KAG S IFGPGTRIPDAA+ V+D +  N
Sbjct:   27 YSSKKPIDTEWAEGAKKELKGKDVEETLTWKTHEGIEIKPVYTQDDTSHMPKEIPGKYPYTRGPYSTMYTHRPWTIRQYAGFSTVEESNKFYRENIAAGQQGLSVAFDLATHRGYDSDNQRVLGDVGMAGVAIDSVEDTNILFDGIPLNKISTSMTMNGAVLPIMAMYIVSAEEQGAKQSELAGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFSYTAKNMPKFNSISISGYHMQEAGADAVLELAFTIADGLQYIRTGLESGLDIDKFAPRLSFFWGIGMTFYMEIAKLRAARKLWAELVKEKFKPTNKKSLLLRAHCQTSGWSLTEQDPYNNIIRTAIEGMAAVFGGTQSLHTNSFDEALGLPTKFSARIARNTQIILQEESGVAKVADPWGGSHMMECLTDDIYQAAKTLINEIEEMGGMAKAVASGMPKLRIEECAARRQARIDSGQEVIVGVNKYRLKDQESVDVLVVDNTAVRESQIARLKQLRENRDSNKVEQVLSAITECCKTDKGNLLELSIEAARARCTVGEITDAMEKVFNRHTATGRLVSGAYKTEFGDKDEIAKVSKRIEKFIEHEGRRPRILVAKVGQDGHDRGGKVIATGFADVGFDVDIGPLFATPKEAAQQAVDADVHVVGVSSLAAGHKSLIPQLVQELKNMGRS------DILVVAGGVIPPQDYDFLYKAGCSAIFGPGTRIPDAALHVIDILESN 737
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. TrEMBL
Match: A0A2B4SH39 (Methylmalonyl-CoA mutase, mitochondrial OS=Stylophora pistillata OX=50429 GN=MUT PE=4 SV=1)

HSP 1 Score: 1104.74 bits (2856), Expect = 0.000e+0
Identity = 532/714 (74.51%), Postives = 614/714 (85.99%), Query Frame = 1 
Query:  121 PLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKNQS 2262
            PLH EW ELAKKQLKGADP++KLTWHT EGIDIKPVYTK DT    EE+PGK+PFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVA+D VEDMK LF+GI L  +S SMTMNGAVLP+LAM++VA EEQG KQE L+GTIQNDILKEFMVRNTYIFPPEPSMKIIGDIF +T+++MPK+NSISISGYHMQEAGA+A+LEMA+T+ADGLEYCRTGLKAGL+ID FAPRLSFFWG+GMNFYMEIAKMRAARR+WA  ++  F  K+ KS +LR HSQTSGWSLTEQDPYNNI+RTTIEAMAAVFGGTQSLHTN+FDEAL LPT FSARIARNTQII+QEE+GI  VADPW GS MME LT+EIY + + +I+EVE MGGMAKAVA G+PKL+IEECAAKRQA ID+G E IVGVNKYRL   E++DVL +DNTKVRESQ+ KIK ++++R+ ++    +  + ECCK+G GNLL +A+ AAR RCTVGEIT+AM  V GRHVA  R+VSGAYK+EFG+  EI+  +KKVE F++ EGRRPRIL+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP E  +QAVDADVHV+G+SS AAGH TL+P+LI+++K+ GR       DIVVV GGVIPPQDY+FL  +GV  IFGPGTRIP AA+ V+DAI  N +
Sbjct:   32 PLHPEWAELAKKQLKGADPEKKLTWHTPEGIDIKPVYTKTDTQHSEEEVPGKFPFTRGPYPTMYTNRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAVDLVEDMKMLFDGIPLDKMSVSMTMNGAVLPVLAMYIVAAEEQGVKQEQLSGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFSFTSQNMPKYNSISISGYHMQEAGADAVLEMAFTLADGLEYCRTGLKAGLNIDSFAPRLSFFWGIGMNFYMEIAKMRAARRLWARQIEENFKPKNMKSCMLRTHSQTSGWSLTEQDPYNNIIRTTIEAMAAVFGGTQSLHTNSFDEALALPTPFSARIARNTQIILQEESGIPNVADPWGGSHMMECLTDEIYEKGLAVINEVEKMGGMAKAVAAGMPKLRIEECAAKRQARIDAGSETIVGVNKYRLAKEEEIDVLVVDNTKVRESQLEKIKRVKETRNQDEVNLAMNAISECCKTGEGNLLDLAVKAARVRCTVGEITEAMERVVGRHVASDRMVSGAYKTEFGESDEINKCMKKVEAFVEQEGRRPRILVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPNEVAQQAVDADVHVVGISSQAAGHKTLIPELISQMKSMGRG------DIVVVCGGVIPPQDYQFLYDSGVHCIFGPGTRIPVAAMDVLDAIQNNNA 739
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. TrEMBL
Match: T1G9F3 (B12-binding domain-containing protein OS=Helobdella robusta OX=6412 GN=20217700 PE=4 SV=1)

HSP 1 Score: 1095.11 bits (2831), Expect = 0.000e+0
Identity = 534/738 (72.36%), Postives = 629/738 (85.23%), Query Frame = 1 
Query:   46 MIRRFSFLKKNLKTLDNYVCYSTQL--PLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIK 2253
            + R  + L K  K+L    C+   +   L  EW ELA+KQLKG DP++KLTWHT EGID+KP+YT+ DT ++ +E+PGKYPFTRGPY TMYT RPWTIRQYAGFSTVEESN+FYK NIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVA+DSVEDMK LF+GI L  +STSMTMNGAVLPILAM+VVA EEQG KQ  L GTIQNDILKEFMVRNTYIFPPEPSM II DIF Y +K++PKFNSISISGYH+QEAGA+A+LE A+T+ADGLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAK+RAAR++WA LLK KF  K   S++LR HSQTSGWSLTEQDPYNNI+RT IEAMA+VFGGTQSLHTN+FDEALGLPT FSARIARNTQIIIQEE+GI KVADPW GS+MME LT+E+Y  A+K+++E+E MGGM+KAVA G+PKL+IEECAA+RQA IDSG E IVGVNKYR   PE V+VL IDNTKVRE QIA++K +R++RDN K Q IL ++ ECCKS HGNLL+++I+AARAR +VGEITDAM  VYGRHVAV RLVSG+YK+E+GD  EI+ VI+++++F+  EGRRPRILIAK+GQDGHDRGGKV+ATGF+D+GFDVD+ PLFSTP EA +QAVD+DVH +GVSSLAAGHMTLVP++I  LK  GR       DI+V  GGVIPP+DY+FL KAG+ +IFGPG+RIPD A++ ++ I++
Sbjct:   10 LYRLSTLLTK--KSLPVSACFERMVGTKLDPEWCELARKQLKGQDPEKKLTWHTAEGIDVKPLYTRDDTAEMAKEVPGKYPFTRGPYATMYTGRPWTIRQYAGFSTVEESNRFYKANIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAVDSVEDMKLLFDGIPLNKLSTSMTMNGAVLPILAMYVVAAEEQGCKQAELAGTIQNDILKEFMVRNTYIFPPEPSMHIIADIFAYLSKNLPKFNSISISGYHIQEAGADAVLETAFTLADGLEYCRTGLKAGLKIDEFAPRLSFFWGIGMNFYMEIAKLRAARKLWATLLKEKFHPKKDLSMMLRCHSQTSGWSLTEQDPYNNIIRTCIEAMASVFGGTQSLHTNSFDEALGLPTPFSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTQEVYEGALKVVNEIEEMGGMSKAVASGMPKLRIEECAARRQARIDSGGETIVGVNKYRPAKPEYVEVLTIDNTKVREQQIARLKHIRETRDNAKVQRILDSITECCKSQHGNLLELSIEAARARASVGEITDAMEKVYGRHVAVHRLVSGSYKNEYGDADEINKVIERIKEFVAIEGRRPRILIAKVGQDGHDRGGKVVATGFADMGFDVDISPLFSTPAEAAQQAVDSDVHAVGVSSLAAGHMTLVPEVIEHLKKLGRP------DILVFVGGVIPPKDYDFLYKAGIVDIFGPGSRIPDCALRTINHIME 739
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. TrEMBL
Match: C3ZCG4 (B12-binding domain-containing protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_245763 PE=4 SV=1)

HSP 1 Score: 1093.95 bits (2828), Expect = 0.000e+0
Identity = 532/709 (75.04%), Postives = 621/709 (87.59%), Query Frame = 1 
Query:  121 PLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAI 2247
            PL +EW +LAKKQLKGADP +KLTWHT EGID+KP++TK+DT     EIPGKYPFTRGPYPTMYT RPWTIRQYAGFSTVEESNKFYK+NIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVA+DSVEDMK LF+GI L+ +S SMTMNGAV+P++AMF+ AGEEQG     LTGTIQNDILKEFMVRNTYI+PP+PSM++IGDIFEYT+++MPKFNSISISGYHMQEAGA+AILE+A+TIADGLEYCRTGLKAGL ID+FAPRLSFFWG+GMNFY+EIAKMRAARR+WA L+K KF +K +KSL+LRAHSQTSGWSLTEQDPYNNIMRTTIEAM+AVFGGTQSLHTN+FDEALGLPT  SARIARNTQII+QEETGI  VADPW GS+MMESLT E+Y  A+ +I+EVE MGGMA+AVAEG+PKL+IEECAA+RQA IDSG+EVIVGVNKYRLE  E V+VL IDNT VRE+Q+ K++ L+ SRDN+K ++ L+ + +  + G GN+LQ+A+DAAR RCTVGEI+DAM +V+GRHVA  R+VSGAYKSEFG+  EI + +++VE F+  EGRRPRIL+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF T  E  +QAVDADVHV+GVS+LAAGH TLVP+LI ELK  GR       DI+VV GGVIPPQDY++L  AG++ IFGPGTRIP AA++V+D I
Sbjct:    5 PLDEEWAQLAKKQLKGADPAEKLTWHTPEGIDVKPLFTKKDTDNTEHEIPGKYPFTRGPYPTMYTGRPWTIRQYAGFSTVEESNKFYKENIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAVDSVEDMKALFDGIPLEKMSVSMTMNGAVIPVMAMFIGAGEEQGVSPSQLTGTIQNDILKEFMVRNTYIYPPDPSMRLIGDIFEYTSQNMPKFNSISISGYHMQEAGADAILELAFTIADGLEYCRTGLKAGLDIDKFAPRLSFFWGIGMNFYLEIAKMRAARRLWAHLMKEKFGAKKEKSLMLRAHSQTSGWSLTEQDPYNNIMRTTIEAMSAVFGGTQSLHTNSFDEALGLPTVTSARIARNTQIILQEETGIANVADPWGGSYMMESLTNEVYDAALGVINEVEEMGGMARAVAEGMPKLRIEECAARRQARIDSGQEVIVGVNKYRLEKEESVEVLSIDNTAVREAQMEKLRQLKASRDNSKVEAALEAIRQGAQ-GDGNMLQLAVDAARIRCTVGEISDAMASVFGRHVASDRMVSGAYKSEFGESDEIQSAMRRVEAFMSAEGRRPRILVAKVGQDGHDRGAKVIATGFADLGFDVDIGPLFQTAAEVAQQAVDADVHVVGVSTLAAGHKTLVPELIHELKEMGR------GDIIVVCGGVIPPQDYDYLYAAGIASIFGPGTRIPIAAMEVLDNI 706
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Cavefish
Match: mut (methylmalonyl-CoA mutase [Source:NCBI gene;Acc:103027932])

HSP 1 Score: 1057.36 bits (2733), Expect = 0.000e+0
Identity = 523/714 (73.25%), Postives = 604/714 (84.59%), Query Frame = 1 
Query:  115 QLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKN 2256
            ++ LH+ W  LAKKQLKG +P + L W T EGI IKPVYT+ DT  + +E+PG +P+TRGPYPTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDL THRGYDSDNPRV GDVGMAGVAID+VEDMK LF+GI L+ +S SMTMNGAV+PILAMF+V GEEQG  +  LTGTIQNDILKEFMVRNTYIFPPEPSM  I DIF YT+K+MPKFNSISISGYH+QEAGA+AILE+AYTIA+GLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAKMRAARR+WA L+K KF  K+ KSLLLR H QTSGWSLTEQDPYNN++RT IEAMAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS+MME+LT ++Y  AMK I+E+E MGGMA+AVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKYRLEN E VDVL IDNT VR  QI K++ +R+ RD + A+  L  +E+C ++ +GNLL++A+ AARARC+VGEITDAM AV+G H A  R+VSGAY+SEFG+ +EI+    +V  F K EGR PR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP E  +QAVDADVH +GVS+LAAGH TLVP+LI EL+N  R       DI+V+ GGVIPPQDYEFL ++GV  IFGPGTRIP AA++VVD I K+
Sbjct:   45 EVQLHEAWAALAKKQLKGKNP-EDLIWRTPEGISIKPVYTQTDTAAVADELPGVFPYTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLPTHRGYDSDNPRVHGDVGMAGVAIDTVEDMKMLFDGIPLERMSVSMTMNGAVIPILAMFIVTGEEQGVDKAKLTGTIQNDILKEFMVRNTYIFPPEPSMHAIADIFAYTSKNMPKFNSISISGYHLQEAGADAILELAYTIANGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAARRLWATLIKEKFQPKNSKSLLLRTHCQTSGWSLTEQDPYNNVIRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMEALTSDVYNSAMKFIEEIEDMGGMARAVAEGIPKLRIEECAARRQARIDSGTEVIVGVNKYRLENEETVDVLAIDNTIVRNKQIEKLQKVREGRDADAAKRCLAAIEQCAQTRNGNLLELAVQAARARCSVGEITDAMKAVFGEHKASTRMVSGAYRSEFGEHEEIALAHSRVLQFKKHEGRNPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPLEVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELRNLNRP------DILVICGGVIPPQDYEFLYQSGVCCIFGPGTRIPQAAVEVVDNIEKS 751
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Nematostella
Match: EDO48863 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHJ6])

HSP 1 Score: 1087.79 bits (2812), Expect = 0.000e+0
Identity = 539/774 (69.64%), Postives = 621/774 (80.23%), Query Frame = 1 
Query:  121 PLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLT----------------------------------------------------EQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKNQSGHGNKKQA 2286
            PLH EW ELAKKQLKG DPKQKLTWHT EGIDIKP+YTK DT  +++E+PGK+PFTRGP PTMYT RPWTIRQYAGFSTVEESNKFY+DNIKAG QGLSVAFDLATHRGYDSDNPRV GDVGMAGVA+DSVEDMK LF+GI L+ +S SMTMNGAVLP+LAM++VA EEQG KQE LTGTIQNDILKEFMVRNTYIFPPEPSMKI+GDIF+YT++HMPK+NSISISGYHMQEAGA+A+LEMA+TIADGLEYCRTGLKAGL ID FAPRLSFFWGVGMNFYMEIAKMRAARR+WA+L++  F+ K+ KS +LR HSQTSG                                                          DPYNNI+RTTIEAMAAVFGGTQSLHTN+FDEAL LPT FSARIARNTQII+QEE+GI KVADPW GS+MMESLT+EIY   MK+I EVE +GGMAKAVA+G+PKL+IEECAAKRQA IDSG E IVGVNK+RL   E+V+VL +DNT+VRE Q+ K+K +R  R+N +    +  + ECCK+G GNLL++AI A+R RCT+GEIT+AM  V GRHVA  R+VSGAYKSE+GD  EI   + +VE+F++ EGRRPRIL+AK+GQDGHDRGGKVIATGF+DLGFDVD+GPLF TP+E  +QAVDADVHV+GVSS AAGH TL+P+L+ EL   GRS      DIVVV GGVIPPQDY+FL KAGV+ IFGPGTRIP AAI+VV+AI  N  G+ +KK +
Sbjct:   32 PLHPEWSELAKKQLKGVDPKQKLTWHTPEGIDIKPLYTKNDTAHMSDELPGKFPFTRGPNPTMYTNRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAVDSVEDMKALFDGIPLEKMSVSMTMNGAVLPVLAMYIVAAEEQGVKQEQLTGTIQNDILKEFMVRNTYIFPPEPSMKIVGDIFQYTSQHMPKYNSISISGYHMQEAGADAVLEMAFTIADGLEYCRTGLKAGLDIDNFAPRLSFFWGVGMNFYMEIAKMRAARRLWADLIQKNFNPKNSKSCMLRTHSQTSGCKFQSFGCIGIRRNADLRSVFAIKAPLPSELGDPELGFCCLGAGLRMRRFRRDTGERDDPYNNIIRTTIEAMAAVFGGTQSLHTNSFDEALALPTPFSARIARNTQIILQEESGIPKVADPWGGSYMMESLTDEIYEAGMKVIQEVEELGGMAKAVAQGMPKLRIEECAAKRQARIDSGSETIVGVNKHRLGKEEQVEVLVVDNTRVREQQVQKLKKIRDVRNNEEVTKAMDAITECCKTGQGNLLELAIQASRVRCTLGEITEAMERVVGRHVARDRMVSGAYKSEYGDTDEIKQCMNRVEEFVEVEGRRPRILVAKMGQDGHDRGGKVIATGFADLGFDVDIGPLFQTPEEVAQQAVDADVHVVGVSSQAAGHKTLIPELVKELNKMGRS------DIVVVCGGVIPPQDYDFLYKAGVTSIFGPGTRIPVAAIEVVNAISNNTGGNVHKKSS 799
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Medaka
Match: mut (methylmalonyl-CoA mutase [Source:NCBI gene;Acc:101161936])

HSP 1 Score: 1051.97 bits (2719), Expect = 0.000e+0
Identity = 520/711 (73.14%), Postives = 598/711 (84.11%), Query Frame = 1 
Query:  124 LHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKN 2256
            LH EW  LAKKQLKG +P + L W T EGI IKPVYT+ D+    +E+PG +P+TRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDL THRGYDSDNPRV GDVGMAGVAIDSVEDMK LF+ I L+ +S SMTMNGAV+P+LAMF+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSM  I DIF YT+K+MPKFNSISISGYH+QEAGA+AILE+AYTIA+GLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAK+RAARR+WA LLK  F  K  KSLLLR H QTSGWSLTEQDPYNN++RT IE MAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS MME+LT+++Y  A+K I E+E MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKYRLE  E V+VL IDNT VR+ QI K+K +R+SRD   A+S L  +EEC ++  GNLL +A++AARARC+VGEITDAM  V+G H A  R+VSGAY+SEFG+ +EI+ V  +V +F + EGR PR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP E  +QAVDADVH +G+S+LAAGH TLVP+LI EL+   R       DI+V+ GGVIPPQDYEFL ++GV  IFGPGTRIP AA++V+D+I K+
Sbjct:   43 LHPEWASLAKKQLKGKNP-EDLIWRTPEGISIKPVYTQADSEGRADELPGTFPYTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLPTHRGYDSDNPRVHGDVGMAGVAIDSVEDMKLLFDEIPLEKMSVSMTMNGAVIPVLAMFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMHAIADIFAYTSKNMPKFNSISISGYHLQEAGADAILELAYTIANGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKLRAARRLWATLLKENFQPKISKSLLLRTHCQTSGWSLTEQDPYNNVIRTVIEGMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSHMMETLTDDVYDAALKFIKEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYRLEKEETVEVLAIDNTVVRQKQIEKLKKVRESRDPEAARSCLAAIEECARTREGNLLALAVEAARARCSVGEITDAMKRVFGEHKASTRMVSGAYRSEFGEHEEIAVVHNRVVEFKRHEGRNPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPLEVAQQAVDADVHCVGISTLAAGHKTLVPELIKELRKLNRP------DILVICGGVIPPQDYEFLYRSGVCAIFGPGTRIPQAAVEVIDSIEKS 746
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Medaka
Match: mut (methylmalonyl-CoA mutase [Source:NCBI gene;Acc:101161936])

HSP 1 Score: 1051.97 bits (2719), Expect = 0.000e+0
Identity = 520/711 (73.14%), Postives = 598/711 (84.11%), Query Frame = 1 
Query:  124 LHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKN 2256
            LH EW  LAKKQLKG +P + L W T EGI IKPVYT+ D+    +E+PG +P+TRGPYPTMYT RPWTIRQYAGFSTVEESNKFYKDNIKAG QGLSVAFDL THRGYDSDNPRV GDVGMAGVAIDSVEDMK LF+ I L+ +S SMTMNGAV+P+LAMF+V GEEQG  +E LTGTIQNDILKEFMVRNTYIFPPEPSM  I DIF YT+K+MPKFNSISISGYH+QEAGA+AILE+AYTIA+GLEYCRTGLKAGL IDEFAPRLSFFWG+GMNFYMEIAK+RAARR+WA LLK  F  K  KSLLLR H QTSGWSLTEQDPYNN++RT IE MAAVFGGTQSLHTN+FDEALGLPT  SARIARNTQIIIQEE+GI KVADPW GS MME+LT+++Y  A+K I E+E MGGMAKAVAEGIPKL+IEECAA+RQA IDSG EVIVGVNKYRLE  E V+VL IDNT VR+ QI K+K +R+SRD   A+S L  +EEC ++  GNLL +A++AARARC+VGEITDAM  V+G H A  R+VSGAY+SEFG+ +EI+ V  +V +F + EGR PR+L+AK+GQDGHDRG KVIATGF+DLGFDVD+GPLF TP E  +QAVDADVH +G+S+LAAGH TLVP+LI EL+   R       DI+V+ GGVIPPQDYEFL ++GV  IFGPGTRIP AA++V+D+I K+
Sbjct:   43 LHPEWASLAKKQLKGKNP-EDLIWRTPEGISIKPVYTQADSEGRADELPGTFPYTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLPTHRGYDSDNPRVHGDVGMAGVAIDSVEDMKLLFDEIPLEKMSVSMTMNGAVIPVLAMFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMHAIADIFAYTSKNMPKFNSISISGYHLQEAGADAILELAYTIANGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKLRAARRLWATLLKENFQPKISKSLLLRTHCQTSGWSLTEQDPYNNVIRTVIEGMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSHMMETLTDDVYDAALKFIKEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYRLEKEETVEVLAIDNTVVRQKQIEKLKKVRESRDPEAARSCLAAIEECARTREGNLLALAVEAARARCSVGEITDAMKRVFGEHKASTRMVSGAYRSEFGEHEEIAVVHNRVVEFKRHEGRNPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPLEVAQQAVDADVHCVGISTLAAGHKTLVPELIKELRKLNRP------DILVICGGVIPPQDYEFLYRSGVCAIFGPGTRIPQAAVEVIDSIEKS 746
[Close]
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Planmine SMEST
Match: SMESG000014335.1 (SMESG000014335.1)

HSP 1 Score: 1471.06 bits (3807), Expect = 0.000e+0
Identity = 743/749 (99.20%), Postives = 743/749 (99.20%), Query Frame = 1 
Query:   46 MIRRFSFLKKNLKTLDNYVCYSTQLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAEXXXXXXXXXXXXXXXXRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNXXXXXXXXXXXXKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKNQSGHGNKKQAVH 2292
            MIRRFSFLKKNLKTLDNYVCYSTQLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAELLKTKFDSKDKKSLLLRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNTQIIIQEETGITKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRS      DIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKNQSGHGNKKQAVH
Sbjct:    1 MIRRFSFLKKNLKTLDNYVCYSTQLPLHKEWVELAKKQLKGADPKQKLTWHTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQEMLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISISGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGVGMNFYMEIAKMRAARRVWAELLKTKFDSKDKKSLLLRAHSQTSGWSLTEQDPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNTQIIIQEETGITKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAEGIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVRESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCTVGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTEGRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQAVDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRS------DIVVVAGGVIPPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKNQSGHGNKKQAVH 743
The following BLAST results are available for this feature:
BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
MMUT0.000e+074.33methylmalonyl-CoA mutase [Source:HGNC Symbol;Acc:H... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mmcm-10.000e+070.61Probable methylmalonyl-CoA mutase, mitochondrial ... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mut0.000e+072.89methylmalonyl CoA mutase [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
camsap30.000e+074.72calmodulin regulated spectrin associated protein f... [more]
camsap30.000e+074.72calmodulin regulated spectrin associated protein f... [more]
camsap30.000e+074.72calmodulin regulated spectrin associated protein f... [more]
camsap30.000e+074.72calmodulin regulated spectrin associated protein f... [more]
camsap30.000e+074.72calmodulin regulated spectrin associated protein f... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Mmut0.000e+074.61methylmalonyl-Coenzyme A mutase [Source:MGI Symbol... [more]
Mmut3.192e-7265.68methylmalonyl-Coenzyme A mutase [Source:MGI Symbol... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9GK13|MUTA_BOVIN0.000e+075.04Methylmalonyl-CoA mutase, mitochondrial OS=Bos tau... [more]
sp|P16332|MUTA_MOUSE0.000e+074.61Methylmalonyl-CoA mutase, mitochondrial OS=Mus mus... [more]
sp|Q8HXX1|MUTA_MACFA0.000e+074.19Methylmalonyl-CoA mutase, mitochondrial OS=Macaca ... [more]
sp|P22033|MUTA_HUMAN0.000e+074.33Methylmalonyl-CoA mutase, mitochondrial OS=Homo sa... [more]
sp|Q5RFN2|MUTA_PONAB0.000e+074.33Methylmalonyl-CoA mutase, mitochondrial OS=Pongo a... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3HQ430.000e+076.21methylmalonyl-CoA mutase, mitochondrial OS=Lingula... [more]
V4AHG90.000e+075.03B12-binding domain-containing protein OS=Lottia gi... [more]
A0A2B4SH390.000e+074.51Methylmalonyl-CoA mutase, mitochondrial OS=Styloph... [more]
T1G9F30.000e+072.36B12-binding domain-containing protein OS=Helobdell... [more]
C3ZCG40.000e+075.04B12-binding domain-containing protein (Fragment) O... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mut0.000e+073.25methylmalonyl-CoA mutase [Source:NCBI gene;Acc:103... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO488630.000e+069.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mut0.000e+073.14methylmalonyl-CoA mutase [Source:NCBI gene;Acc:101... [more]
mut0.000e+073.14methylmalonyl-CoA mutase [Source:NCBI gene;Acc:101... [more]
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BLAST of methylmalonyl-CoA mutase, mitochondrial vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000014335.10.000e+099.20SMESG000014335.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016140 ID=SMED30016140|Name=methylmalonyl-CoA mutase, mitochondrial|organism=Schmidtea mediterranea sexual|type=transcript|length=2419bp
ATATCATTCAAATAATTATTTGAGTTCGTGACTTATTTCGGTAACATGAT
TCGACGTTTTTCATTTCTGAAAAAAAATTTGAAGACCCTAGATAACTATG
TATGTTATTCAACACAACTGCCTCTTCATAAAGAATGGGTTGAATTAGCA
AAAAAACAATTGAAAGGAGCGGATCCAAAACAAAAATTAACTTGGCATAC
CCAAGAAGGAATTGATATTAAACCAGTATATACTAAGCAAGATACTACCA
AACTTAATGAAGAAATTCCTGGAAAGTATCCATTTACTCGAGGTCCTTAC
CCAACAATGTATACTCAACGACCTTGGACTATTAGACAGTATGCTGGATT
TTCAACTGTCGAGGAAAGTAATAAATTCTATAAAGATAACATCAAAGCTG
GTGTGCAAGGTTTAAGTGTAGCGTTTGATTTAGCTACACATAGAGGTTAT
GATTCCGATAACCCGCGAGTTTTTGGTGACGTTGGTATGGCCGGAGTAGC
AATTGACTCAGTTGAAGACATGAAAAGGCTTTTCGAAGGAATAGAATTGA
AAAATATTTCAACATCAATGACGATGAATGGAGCGGTTTTGCCCATCTTA
GCCATGTTTGTTGTTGCTGGAGAAGAACAGGGTACCAAACAAGAAATGCT
AACAGGCACAATTCAAAATGATATATTAAAGGAATTTATGGTCAGAAATA
CATACATTTTCCCTCCGGAGCCTTCAATGAAAATAATCGGCGATATTTTT
GAATACACAGCTAAACACATGCCAAAATTTAATTCGATTTCAATTTCCGG
TTATCATATGCAAGAAGCTGGCGCTAACGCAATTTTGGAAATGGCATATA
CTATTGCGGATGGTCTTGAATATTGCCGAACTGGTTTAAAAGCCGGCCTC
CATATTGATGAGTTCGCACCGCGTCTCTCATTCTTTTGGGGTGTTGGCAT
GAATTTCTACATGGAAATCGCGAAGATGAGAGCTGCTAGACGAGTGTGGG
CTGAATTACTAAAAACTAAGTTTGATTCTAAAGACAAAAAATCATTATTA
TTAAGAGCACATTCTCAAACATCTGGATGGTCTCTAACGGAACAGGATCC
ATATAATAATATAATGCGGACTACCATTGAAGCTATGGCTGCAGTTTTTG
GCGGAACTCAATCTTTACATACAAATGCATTTGATGAAGCTTTAGGTCTG
CCAACGAAATTTTCCGCTAGAATCGCTCGTAATACTCAAATAATTATTCA
AGAAGAAACTGGTATTACCAAGGTGGCCGATCCCTGGGCAGGTTCATTCA
TGATGGAAAGTTTGACTGAAGAAATTTACACCGAAGCTATGAAAATTATC
GACGAAGTCGAAGCTATGGGTGGAATGGCTAAGGCTGTTGCTGAGGGAAT
TCCAAAATTGAAAATTGAAGAATGTGCAGCAAAAAGACAAGCACATATTG
ATTCTGGAAAAGAGGTTATTGTCGGAGTAAATAAGTATCGCCTTGAAAAT
CCAGAAAAGGTTGATGTACTTCATATTGATAATACTAAAGTCCGAGAATC
TCAAATTGCTAAAATTAAAGCTCTCCGCCAGTCTAGGGACAACAATAAAG
CTCAAAGTATTCTTAAAACCCTTGAAGAATGTTGTAAAAGTGGTCATGGA
AATCTTTTACAAATCGCAATAGATGCAGCCAGAGCCCGCTGTACGGTTGG
AGAAATAACAGATGCTATGGTTGCAGTATATGGTCGACATGTTGCTGTGG
GTAGATTAGTTAGCGGAGCATACAAATCTGAGTTTGGTGATGATAAAGAA
ATATCTGCTGTTATCAAAAAAGTTGAGGATTTCTTGAAAACCGAAGGCAG
GAGACCAAGAATTTTGATTGCGAAACTGGGCCAAGATGGTCATGATCGAG
GTGGTAAGGTAATTGCTACCGGATTCTCTGATTTAGGTTTTGATGTTGAC
GTTGGTCCATTGTTTTCTACACCTAAAGAAGCTGTTGAACAAGCAGTTGA
TGCTGATGTTCATGTAATCGGAGTTAGTTCATTGGCTGCAGGTCATATGA
CTTTGGTGCCGCAGCTGATTGCAGAATTAAAAAATGCTGGTCGGAGTCAA
ATTGTAAGGATCAATGACATTGTAGTGGTTGCAGGTGGAGTTATTCCCCC
TCAAGATTATGAATTTTTACGAAAAGCTGGGGTTTCTGAAATTTTTGGAC
CAGGAACTCGTATTCCGGATGCAGCAATAAAGGTTGTAGATGCAATCATT
AAAAACCAATCCGGTCATGGAAACAAGAAACAAGCGGTTCACTAACGTAT
TGCTTACTCAAACATCATAATTCTATAAATAAACTCATGCTTTGGAAATT
ATAATTAGTGTTTGCCATATGAAACATTAATTTATACTCATTAATAAAAC
CTTAACTACAGATCGGAAG
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protein sequence of SMED30016140-orf-1

>SMED30016140-orf-1 ID=SMED30016140-orf-1|Name=SMED30016140-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=750bp
MIRRFSFLKKNLKTLDNYVCYSTQLPLHKEWVELAKKQLKGADPKQKLTW
HTQEGIDIKPVYTKQDTTKLNEEIPGKYPFTRGPYPTMYTQRPWTIRQYA
GFSTVEESNKFYKDNIKAGVQGLSVAFDLATHRGYDSDNPRVFGDVGMAG
VAIDSVEDMKRLFEGIELKNISTSMTMNGAVLPILAMFVVAGEEQGTKQE
MLTGTIQNDILKEFMVRNTYIFPPEPSMKIIGDIFEYTAKHMPKFNSISI
SGYHMQEAGANAILEMAYTIADGLEYCRTGLKAGLHIDEFAPRLSFFWGV
GMNFYMEIAKMRAARRVWAELLKTKFDSKDKKSLLLRAHSQTSGWSLTEQ
DPYNNIMRTTIEAMAAVFGGTQSLHTNAFDEALGLPTKFSARIARNTQII
IQEETGITKVADPWAGSFMMESLTEEIYTEAMKIIDEVEAMGGMAKAVAE
GIPKLKIEECAAKRQAHIDSGKEVIVGVNKYRLENPEKVDVLHIDNTKVR
ESQIAKIKALRQSRDNNKAQSILKTLEECCKSGHGNLLQIAIDAARARCT
VGEITDAMVAVYGRHVAVGRLVSGAYKSEFGDDKEISAVIKKVEDFLKTE
GRRPRILIAKLGQDGHDRGGKVIATGFSDLGFDVDVGPLFSTPKEAVEQA
VDADVHVIGVSSLAAGHMTLVPQLIAELKNAGRSQIVRINDIVVVAGGVI
PPQDYEFLRKAGVSEIFGPGTRIPDAAIKVVDAIIKNQSGHGNKKQAVH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000101muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR006098MMCoA_mutase_a_cat
IPR006159Acid_CoA_mut_C
IPR036724Cobalamin-bd_sf
IPR006099MeMalonylCoA_mutase_a/b_cat
IPR006158Cobalamin-bd
IPR014348Cbl-dep_enz_cat-sub
IPR016176Cbl-dep_enz_cat
Vocabulary: biological process
TermDefinition
GO:0008152metabolic process
Vocabulary: molecular function
TermDefinition
GO:0016866intramolecular transferase activity
GO:0031419cobalamin binding
GO:0046872metal ion binding
GO:0003824catalytic activity
GO:0004494methylmalonyl-CoA mutase activity
GO:0016853isomerase activity
Vocabulary: cellular component
TermDefinition
GO:0005739mitochondrion
GO:0005759mitochondrial matrix
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006099Methylmalonyl-CoA mutase, alpha/beta chain, catalyticPFAMPF01642MM_CoA_mutasecoord: 1..416
e-value: 5.5E-190
score: 632.3
IPR006099Methylmalonyl-CoA mutase, alpha/beta chain, catalyticPROSITEPS00544METMALONYL_COA_MUTASEcoord: 245..270
IPR006158Cobalamin (vitamin B12)-binding domainPFAMPF02310B12-bindingcoord: 458..575
e-value: 2.9E-12
score: 46.7
IPR006158Cobalamin (vitamin B12)-binding domainPROSITEPS51332B12_BINDINGcoord: 456..594
score: 33.243
NoneNo IPR availableGENE3DG3DSA:3.20.20.240coord: 1..418
e-value: 4.0E-195
score: 651.0
NoneNo IPR availableGENE3DG3DSA:3.40.50.280coord: 422..590
e-value: 1.5E-54
score: 185.9
NoneNo IPR availablePANTHERPTHR42710:SF1METHYLMALONYL-COA MUTASE, MITOCHONDRIALcoord: 1..592
NoneNo IPR availablePANTHERPTHR42710FAMILY NOT NAMEDcoord: 1..592
NoneNo IPR availableCDDcd02071MM_CoA_mut_B12_BDcoord: 458..585
e-value: 2.46304E-60
score: 194.348
IPR006098Methylmalonyl-CoA mutase, alpha chain, catalyticTIGRFAMTIGR00641TIGR00641coord: 1..420
e-value: 3.9E-217
score: 719.6
IPR006159Methylmalonyl-CoA mutase, C-terminalTIGRFAMTIGR00640TIGR00640coord: 455..590
e-value: 1.1E-58
score: 194.9
IPR016176Cobalamin (vitamin B12)-dependent enzyme, catalyticSUPERFAMILYSSF51703Cobalamin (vitamin B12)-dependent enzymescoord: 2..418
IPR036724Cobalamin-binding domain superfamilySUPERFAMILYSSF52242Cobalamin (vitamin B12)-binding domaincoord: 424..590