SMED30016113

Overview


Name	SMED30016113
Smed ID	SMED30016113
Length (bp)	983

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30016113 (SMED30016113) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30016113 (SMED30016113) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30016113

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
epidermis	SMED30016113	SMESG000053522.1	dd_Smed_v4_548_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30016113	SMESG000053522.1	dd_Smed_v4_548_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30016113	SMESG000053522.1	dd_Smed_v4_548_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30016113	SMESG000053522.1	dd_Smed_v4_548_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30016113	SMESG000053522.1	dd_Smed_v4_548_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30016113	SMESG000053522.1	dd_Smed_v4_548_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016113	SMESG000053522.1	Contig49190	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016113	SMESG000053522.1	Contig49190	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016113	SMESG000071539.1	Contig4711	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30016113	SMESG000053522.1	Contig4711	GPL15192	PMID:29674431 Fincher et al., 2018
head region	SMED30016113	SMESG000053522.1	OX_Smed_1.0.22806	ox_Smed_v2	PMID:24238224 Kao et al., 2013
neoblast	SMED30016113	SMESG000053522.1	SMED_00102_V2_1r	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30016113	SMESG000053522.1	SMED_00102_V2_1r	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Alignments

SMED30016113 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.003522:8021..9514 -	4869

Homology

[Close]

BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305])

HSP 1 Score: 303.908 bits (777), Expect = 1.395e-103
Identity = 144/211 (68.25%), Postives = 175/211 (82.94%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I+L   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 296.975 bits (759), Expect = 7.964e-101
Identity = 139/212 (65.57%), Postives = 173/212 (81.60%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR++GDLSHL A+I+LL KIW+++ C G+SGK+QILF +VFTTRYLDLFTNF+S YNT MK++FL   Y TV+ IY KFR T+ S +DTFR+EF+L+P   L+ LEN+   L+EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI RY TE  YD I +V+G VQT+F+ DFFYLY T+VLKGK + LP+
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPM 212

[Close]

BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 281.567 bits (719), Expect = 1.042e-94
Identity = 132/201 (65.67%), Postives = 164/201 (81.59%), Query Frame = -2

Query:  272 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATR 874
            MN+FR++GDLSHL A+I+LL KIW+++ C G+SGK+QILF +VFTTRYLDLFTNF+S YNT MK++FL   Y TV+ IY KFR T+ S +DTFR+EF+L+P   L+ LEN+   L+EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI RY TE  YD I +V+G VQT+F+ DFFYLY T+
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTK 201

[Close]

BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 275.404 bits (703), Expect = 1.978e-92
Identity = 141/212 (66.51%), Postives = 174/212 (82.08%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR +GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFT RYLDLFTN++S YNT MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 199.134 bits (505), Expect = 2.387e-63
Identity = 95/149 (63.76%), Postives = 118/149 (79.19%), Query Frame = -2

Query:  242 MKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 688
            MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 149

[Close]

BLAST of SMED30016113 vs. Ensembl Celegans
Match: erd-2.1 (ER lumen protein-retaining receptor [Source:UniProtKB/Swiss-Prot;Acc:P48583])

HSP 1 Score: 273.863 bits (699), Expect = 2.986e-92
Identity = 126/206 (61.17%), Postives = 166/206 (80.58%), Query Frame = -2

Query:  257 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGK 874
            MN+FR   D++H  AI++LLLKIWK+RSC G+SG++Q+LF +VF TRYLDLFTNF S YNTAMKI +L   + TV+ ++ KF+ATY   +D+FR+EF++IP+  LA+L NH+   ME++WTFSIYLE++AI+PQLFM++ TG+AETIT HYLFALG YR LYI+NW+YRYYTE  +D I +VAG VQTV + DFFYLY TRV++  
Sbjct:    1 MNLFRFTADVAHAIAIVVLLLKIWKSRSCEGISGRSQLLFALVFVTRYLDLFTNFFSFYNTAMKIFYLVASFGTVYLMWAKFKATYDRNNDSFRIEFLVIPSMILALLINHEFIFMEVMWTFSIYLEAVAIMPQLFMLSRTGNAETITAHYLFALGSYRFLYILNWVYRYYTESFFDPISVVAGIVQTVLYADFFYLYITRVIQSN 206

[Close]

BLAST of SMED30016113 vs. Ensembl Celegans
Match: erd-2.2 (Putative ER lumen protein-retaining receptor C28H8.4 [Source:UniProtKB/Swiss-Prot;Acc:Q09473])

HSP 1 Score: 257.684 bits (657), Expect = 6.490e-86
Identity = 135/213 (63.38%), Postives = 167/213 (78.40%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKG-KDVILPV 874
            MNIFR+  D+SHL AIIILLLKIWK+RSC+G+S ++QILF +VFT RYLDLF+ ++S YNT MKI FL   Y TV+ ++ KFR+TY    DTFRVE +++P   LA+L NH     E+LWTFSIYLE++AILPQLF++ +TGSAE IT HYLFALG YRALYI NWIYRYYTE  +D IV+VAG VQTV + DFFYLY TRV++  K + LP+
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELPI 213

[Close]

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKG-KDVILPV 874
            MNIFR+  D+SHL AIIILLLKIWK+RSC+G+S ++QILF +VFT RYLDLF+ ++S YNT MKI FL   Y TV+ ++ KFR+TY    DTFRVE +++P   LA+L NH     E+LWTFSIYLE++AILPQLF++ +TGSAE IT HYLFALG YRALYI NWIYRYYTE  +D IV+VAG VQTV + DFFYLY TRV++  K + LP+
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELPI 213

[Close]

BLAST of SMED30016113 vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080021)

HSP 1 Score: 287.345 bits (734), Expect = 2.000e-97
Identity = 136/211 (64.45%), Postives = 170/211 (80.57%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFR  GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ TRYLDLFT +VS YN+ MK++FL     TV+ +Y KF+ATY    D+FR+EF+L+P   L+++ NH+  +ME+LWTFSIYLES+AILPQLF+++ TG AE+IT HYLFALG YRALY++NW+YRY  E  YD+I I AG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080023)

HSP 1 Score: 287.345 bits (734), Expect = 2.000e-97
Identity = 136/211 (64.45%), Postives = 170/211 (80.57%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFR  GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ TRYLDLFT +VS YN+ MK++FL     TV+ +Y KF+ATY    D+FR+EF+L+P   L+++ NH+  +ME+LWTFSIYLES+AILPQLF+++ TG AE+IT HYLFALG YRALY++NW+YRY  E  YD+I I AG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080022)

HSP 1 Score: 287.345 bits (734), Expect = 2.000e-97
Identity = 136/211 (64.45%), Postives = 170/211 (80.57%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFR  GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ TRYLDLFT +VS YN+ MK++FL     TV+ +Y KF+ATY    D+FR+EF+L+P   L+++ NH+  +ME+LWTFSIYLES+AILPQLF+++ TG AE+IT HYLFALG YRALY++NW+YRY  E  YD+I I AG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: kdelr2a (KDEL endoplasmic reticulum protein retention receptor 2a [Source:NCBI gene;Acc:373129])

HSP 1 Score: 305.064 bits (780), Expect = 2.882e-104
Identity = 146/212 (68.87%), Postives = 171/212 (80.66%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KFRATY    DTFR EF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: kdelr2b (KDEL endoplasmic reticulum protein retention receptor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-4189])

HSP 1 Score: 302.368 bits (773), Expect = 3.327e-103
Identity = 144/212 (67.92%), Postives = 173/212 (81.60%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   LA L NH    +EILWTFSIYLES++ILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNLFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTSMKVIYIACAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVSILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:393613])

HSP 1 Score: 283.878 bits (725), Expect = 6.242e-96
Identity = 135/213 (63.38%), Postives = 174/213 (81.69%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MNIFRL GD+ HL AIIIL LKIW+++SCAG+SGK+Q+LF +VFTTRYLDLFT+++SAYNT MK+++L L Y+TV  I+ +FR +Y S  D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYL  LG+YRALY+ NW++R++TEG YD I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 213

[Close]

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MNIFRL GD+ HL AIIIL LKIW+++SCAG+SGK+Q+LF +VFTTRYLDLFT+++SAYNT MK+++L L Y+TV  I+ +FR +Y S  D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYL  LG+YRALY+ NW++R++TEG YD I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 213

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BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: CABZ01075611.1 (pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDARG00000104519.2 transcript:ENSDART00000165169.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01075611.1)

HSP 1 Score: 177.563 bits (449), Expect = 1.855e-54
Identity = 83/138 (60.14%), Postives = 109/138 (78.99%), Query Frame = -2

Query:  272 KIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATR 685
            ++++L L Y+TV  I+ +FR +Y S  D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYL  LG+YRALY+ NW++R++TEG YD I +V+G VQT+F+ DFFYLY TR
Sbjct:   38 QVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTR 175

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BLAST of SMED30016113 vs. Ensembl Xenopus
Match: kdelr2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:496456])

HSP 1 Score: 304.294 bits (778), Expect = 7.091e-104
Identity = 145/212 (68.40%), Postives = 175/212 (82.55%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFR +GD+SHL AI+ILLLKIWK+RSCAG+SGK+Q+LF IVFTTRYLDLFTNF+S YNT+MK++++   Y T++ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALGIYRALY+ NWI+RY  EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRFLGDISHLSAILILLLKIWKSRSCAGISGKSQLLFAIVFTTRYLDLFTNFISLYNTSMKMVYVASSYATIWMIYSKFKATYDGNHDTFRVEFLIVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGIYRALYLFNWIWRYQFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

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BLAST of SMED30016113 vs. Ensembl Xenopus
Match: kdelr1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:NCBI gene;Acc:395012])

HSP 1 Score: 300.056 bits (767), Expect = 3.816e-102
Identity = 143/211 (67.77%), Postives = 173/211 (81.99%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MN+FRL GDLSHL AIIILLLKIWK+RSCAG+SGK+Q+LF +VFTTRYLDL T+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+VL NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+RY  EG +D+I IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNVFRLSGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTSMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSVLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRYSFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211

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BLAST of SMED30016113 vs. Ensembl Xenopus
Match: stx1a (syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753])

HSP 1 Score: 274.248 bits (700), Expect = 1.346e-91
Identity = 136/205 (66.34%), Postives = 169/205 (82.44%), Query Frame = -2

Query:  239 GDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 853
            GD+SHL AIIILLLK+WK++SCAG+SGK+Q+LF +VFTTRYLDLFT F+SAYNT MKI+FL   Y TV+ IY KFR  Y S +DTFR+EF+L+P   L+ LEN++   +EILWTFSIYLES+AILPQLFMI+ TG AE+IT HYLF LG+YR LY+ NWI+RY+TE  YD I +V+G VQT+F+ DFFYLY T+VLKGK + LP+
Sbjct:   37 GDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISAYNTVMKIVFLVCAYVTVYLIYGKFRKAYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILWTFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIAVVSGVVQTIFYFDFFYLYITKVLKGKKLSLPM 241

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BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr2 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 [Source:MGI Symbol;Acc:MGI:1914163])

HSP 1 Score: 302.753 bits (774), Expect = 2.371e-103
Identity = 143/211 (67.77%), Postives = 175/211 (82.94%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211

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BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr3 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 [Source:MGI Symbol;Acc:MGI:2145953])

HSP 1 Score: 290.812 bits (743), Expect = 1.175e-98
Identity = 137/212 (64.62%), Postives = 172/212 (81.13%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR++GDLSHL A+I+LL+KIW+++SCAG+SGK+QILF +VFTTRYLDLF+NF+S YNT MK++FL   Y TV+ IY KFR T+   +DTFR+EF+L+P   L+ L N+    ME+LWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YR LY+ NWI RY TE  YD I +V+G VQT+F+ DFFYLY T+VLKGK + LPV
Sbjct:    1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYNTVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPVTGLSFLVNYSYTPMEVLWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQISVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPV 212

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BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 275.404 bits (703), Expect = 1.548e-92
Identity = 141/212 (66.51%), Postives = 174/212 (82.08%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR +GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFT RYLDLFTN++S YNT MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 199.134 bits (505), Expect = 1.621e-63
Identity = 95/149 (63.76%), Postives = 118/149 (79.19%), Query Frame = -2

Query:  242 MKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 688
            MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 149

[Close]

BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 172.17 bits (435), Expect = 4.102e-53
Identity = 92/137 (67.15%), Postives = 114/137 (83.21%), Query Frame = -2

Query:  464 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFM 874
            MN+FR +GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFT RYLDLFTN++S YNT MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFM 137

[Close]

BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q5ZKX9|ERD22_CHICK (ER lumen protein-retaining receptor 2 OS=Gallus gallus OX=9031 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 305.064 bits (780), Expect = 1.951e-103
Identity = 145/211 (68.72%), Postives = 175/211 (82.94%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+RYY EG +D+I +VAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLIVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRYYFEGFFDLIAVVAGVVQTVLYCDFFYLYVTKVLKGKKLSLP 211

[Close]

BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q6PEH1|ERD22_DANRE (ER lumen protein-retaining receptor 2 OS=Danio rerio OX=7955 GN=kdelr2 PE=2 SV=1)

HSP 1 Score: 305.064 bits (780), Expect = 2.176e-103
Identity = 146/212 (68.87%), Postives = 171/212 (80.66%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KFRATY    DTFR EF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q5XHA2|ERD21_XENTR (ER lumen protein-retaining receptor 1 OS=Xenopus tropicalis OX=8364 GN=kdelr1 PE=2 SV=1)

HSP 1 Score: 304.294 bits (778), Expect = 3.756e-103
Identity = 145/212 (68.40%), Postives = 175/212 (82.55%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFR +GD+SHL AI+ILLLKIWK+RSCAG+SGK+Q+LF IVFTTRYLDLFTNF+S YNT+MK++++   Y T++ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALGIYRALY+ NWI+RY  EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRFLGDISHLSAILILLLKIWKSRSCAGISGKSQLLFAIVFTTRYLDLFTNFISLYNTSMKMVYVASSYATIWMIYSKFKATYDGNHDTFRVEFLIVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGIYRALYLFNWIWRYQFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|P33947|ERD22_HUMAN (ER lumen protein-retaining receptor 2 OS=Homo sapiens OX=9606 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 303.908 bits (777), Expect = 6.701e-103
Identity = 144/211 (68.25%), Postives = 175/211 (82.94%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I+L   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211

[Close]

BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q5U305|ERD22_RAT (ER lumen protein-retaining receptor 2 OS=Rattus norvegicus OX=10116 GN=Kdelr2 PE=2 SV=1)

HSP 1 Score: 302.753 bits (774), Expect = 1.659e-102
Identity = 143/211 (67.77%), Postives = 175/211 (82.94%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211

[Close]

BLAST of SMED30016113 vs. TrEMBL
Match: A0A3Q0JXJ0 (ER lumen protein-retaining receptor OS=Ciona intestinalis OX=7719 GN=erd2 PE=3 SV=1)

HSP 1 Score: 314.694 bits (805), Expect = 3.484e-104
Identity = 150/223 (67.26%), Postives = 180/223 (80.72%), Query Frame = -2

Query:  239 TRQTEIQFRV*MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 907
            T +  +  ++ MNIFRL GDLSHL AII+LLLKIWKTRSCAG+SGK+QILF +VFTTRYLDLFTNF+S YNT MK+I+L   Y TV+ IY KF+ATY    DTFR EF+++P   LA L NH+   +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLFALG+YRALY+INWI+RYY E  +D+I IVAGCVQT+ + DFFYLY T+VL+GK + LP 
Sbjct:   22 TAKCILNTKIRMNIFRLAGDLSHLAAIIVLLLKIWKTRSCAGISGKSQILFALVFTTRYLDLFTNFISPYNTVMKMIYLGCAYATVYLIYMKFKATYDGNHDTFRAEFLVVPVGGLAFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFALGMYRALYLINWIWRYYFENFFDLIAIVAGCVQTILYCDFFYLYITKVLQGKKLSLPA 244

[Close]

BLAST of SMED30016113 vs. TrEMBL
Match: Q8I7E2 (ER lumen protein-retaining receptor OS=Ciona intestinalis OX=7719 GN=erd2 PE=2 SV=1)

HSP 1 Score: 312.768 bits (800), Expect = 5.265e-104
Identity = 149/212 (70.28%), Postives = 175/212 (82.55%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AII+LLLKIWKTRSCAG+SGK+QILF +VFTTRYLDLFTNF+S YNT MK+I+L   Y TV+ IY KF+ATY    DTFR EF+++P   LA L NH+   +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLFALG+YRALY+INWI+RYY E  +D+I IVAGCVQT+ + DFFYLY T+VL+GK + LP 
Sbjct:    1 MNIFRLAGDLSHLAAIIVLLLKIWKTRSCAGISGKSQILFALVFTTRYLDLFTNFISPYNTVMKMIYLGCAYATVYLIYMKFKATYDGNHDTFRAEFLVVPVGGLAFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFALGMYRALYLINWIWRYYFENFFDLIAIVAGCVQTILYCDFFYLYITKVLQGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. TrEMBL
Match: A0A3Q0JUS8 (ER lumen protein-retaining receptor OS=Ciona intestinalis OX=7719 GN=erd2 PE=3 SV=1)

HSP 1 Score: 313.153 bits (801), Expect = 5.295e-104
Identity = 149/212 (70.28%), Postives = 175/212 (82.55%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AII+LLLKIWKTRSCAG+SGK+QILF +VFTTRYLDLFTNF+S YNT MK+I+L   Y TV+ IY KF+ATY    DTFR EF+++P   LA L NH+   +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLFALG+YRALY+INWI+RYY E  +D+I IVAGCVQT+ + DFFYLY T+VL+GK + LP 
Sbjct:    4 MNIFRLAGDLSHLAAIIVLLLKIWKTRSCAGISGKSQILFALVFTTRYLDLFTNFISPYNTVMKMIYLGCAYATVYLIYMKFKATYDGNHDTFRAEFLVVPVGGLAFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFALGMYRALYLINWIWRYYFENFFDLIAIVAGCVQTILYCDFFYLYITKVLQGKKLSLPA 215

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BLAST of SMED30016113 vs. TrEMBL
Match: A7RJJ4 (ER lumen protein-retaining receptor OS=Nematostella vectensis OX=45351 GN=v1g236409 PE=3 SV=1)

HSP 1 Score: 311.612 bits (797), Expect = 1.553e-103
Identity = 147/211 (69.67%), Postives = 176/211 (83.41%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL+GDLSHL AII+LL KIWKTRSCAGVSGK+Q++F +VF+TRYLDLFT+FVS YN+ MK+I+++  + T++ +Y KF+ATY S  DTFRVEF+LIP   LA L NH+  +ME+LWTFSIYLES+AILPQLFMI+ TG AE+IT HYLFALG YRALYI NW+YRYY EG YD I IVAGCVQT  + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLVGDLSHLVAIILLLWKIWKTRSCAGVSGKSQMMFALVFSTRYLDLFTSFVSLYNSVMKVIYISCAFATLYLMYIKFKATYDSNHDTFRVEFLLIPVAGLACLVNHEFTIMEVLWTFSIYLESVAILPQLFMISKTGEAESITSHYLFALGAYRALYIANWVYRYYFEGFYDFIAIVAGCVQTALYCDFFYLYITKVLKGKSLKLP 211

[Close]

BLAST of SMED30016113 vs. TrEMBL
Match: A0A3Q1JW37 (ER lumen protein-retaining receptor OS=Anabas testudineus OX=64144 PE=3 SV=1)

HSP 1 Score: 310.842 bits (795), Expect = 2.894e-103
Identity = 150/211 (71.09%), Postives = 174/211 (82.46%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRLIGDLSHL AIIILLLKIWK+RSCAG+SGK+QILF IVFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KFRATY    D+FRVEF+++P   LAVL NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLIGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFAIVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSFLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTVLYCDFFYLYVTKVLKGKKLSLP 211

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BLAST of SMED30016113 vs. Ensembl Cavefish
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:103025946])

HSP 1 Score: 305.064 bits (780), Expect = 2.666e-104
Identity = 147/211 (69.67%), Postives = 173/211 (81.99%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+INWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLINWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Cavefish
Match: kdelr2a (ER lumen protein-retaining receptor 2-like [Source:NCBI gene;Acc:103040303])

HSP 1 Score: 303.908 bits (777), Expect = 6.745e-104
Identity = 144/211 (68.25%), Postives = 173/211 (81.99%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWKTRSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KF+ATY    DTFR+EF+++P   LA L NH    +EI+WTFSIYLES+AILPQLF+I+ TG AETIT HYLF+LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLAGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRIEFLIVPVGGLAFLVNHDFSPLEIMWTFSIYLESVAILPQLFLISKTGEAETITTHYLFSLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211

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BLAST of SMED30016113 vs. Ensembl Cavefish
Match: KDELR3 (ER lumen protein-retaining receptor 3 [Source:NCBI gene;Acc:103035602])

HSP 1 Score: 290.812 bits (743), Expect = 1.019e-98
Identity = 134/206 (65.05%), Postives = 170/206 (82.52%), Query Frame = -2

Query:  257 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGK 874
            MN+FRL GD+SHL AII+L LKIW+++SCAG+SGK+Q+LF +VFTTRYLDLFT F+S YNT MK++FL L Y TV+ IY +FR +Y S +D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYLF LG+YRALY+ NW++RY+TE  +D I +V+G VQT+F+ DFFYLY TRVL+G 
Sbjct:    1 MNVFRLCGDVSHLVAIILLFLKIWRSKSCAGISGKSQVLFAVVFTTRYLDLFTGFISIYNTVMKVVFLVLAYATVYLIYLRFRNSYDSENDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITTHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGS 206

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BLAST of SMED30016113 vs. Ensembl Cavefish
Match: ENSAMXT00000042346.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000042346.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.568 bits (327), Expect = 2.969e-36
Identity = 89/222 (40.09%), Postives = 119/222 (53.60%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRY-LDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYR--KFRATYHSVDDTFRVEFILIPTFALAVLEN-----HKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETI-TYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MN+FRL GD+S    + + L         AG+SGK+Q+   +  +    L   T F+S YNT MK+  L  +   + FIY    FR +Y S    F           L+ LE             ILWTFSIYLES+           TG AE+    HYLF LG+YRALY+ NW++RY+TE  +D I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNVFRLCGDVSAFSCLCVCLCVC------AGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGCLPGVGIPLQFIYSTCAFRNSYDS-GMHFISGGSCCSVAGLSFLEKLTPSTPTGGNTPILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 204

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BLAST of SMED30016113 vs. Ensembl Cavefish
Match: ENSAMXT00000040094.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000040094.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.553 bits (301), Expect = 8.918e-33
Identity = 78/215 (36.28%), Postives = 106/215 (49.30%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTR-YLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETI-TYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MN+FRL GD+S     + L +       CAG+SGK+Q+   +  +    L   T F+S YNT MK+      +                                            +ILWTFSIYLES+           TG AE+    HYLF LG+YRALY+ NW++RY+TE  +D I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNVFRLCGDVSAFSLCVCLCV-------CAGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGKHKHTHKHH--------------------TQHTHTHTPHTHTHTTTHPHSQILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 177

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BLAST of SMED30016113 vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 283.878 bits (725), Expect = 9.478e-97
Identity = 144/212 (67.92%), Postives = 178/212 (83.96%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FRL GDLSHL AIIILL+KIWKTRSCAG+SGK+QILF +VFTTRYLDLFT F+S YNT+MK++++   Y T++ IY KF+ATY   +DTFRVEF+++P   L+VL NH   L+EILWTFSIYLES+AILPQLF+++ TG AETIT HYLFALG+YRALY++NWI+RYY EG +D+I IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNVFRLTGDLSHLLAIIILLIKIWKTRSCAGISGKSQILFALVFTTRYLDLFTTFISIYNTSMKVVYMACAYATLWMIYHKFKATYDGNNDTFRVEFLVVPIGGLSVLVNHDFSLLEILWTFSIYLESVAILPQLFLVSKTGEAETITSHYLFALGLYRALYLLNWIWRYYFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212

[Close]

BLAST of SMED30016113 vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 277.33 bits (708), Expect = 3.991e-94
Identity = 143/211 (67.77%), Postives = 175/211 (82.94%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MN+FRL GDLSHL AIIILLLKIWKTRSCAG+SGK+QILF +VFTTRYLDL TN++S YNT MK+I++   Y TV+ IY KF+ATY S  DTFRVEF+++P   L+++ NH   ++EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNVFRLAGDLSHLLAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTNYISLYNTTMKVIYIGCSYATVWMIYSKFKATYDSNHDTFRVEFLVLPVALLSLVVNHDYSVVEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYFAEGFFDLIAIVAGLVQTILYCDFFYLYITKVLKGKKLSLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Yeast
Match: ERD2 (HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins [Source:SGD;Acc:S000000136])

HSP 1 Score: 185.652 bits (470), Expect = 2.700e-58
Identity = 103/218 (47.25%), Postives = 147/218 (67.43%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFT-NFVSAYNTAMKIIFL-TLIYTTVFFIYRKFRAT--YHSV--DDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLY-DMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MN FR++GDLSHL +I+IL+  I  TR   G+S KTQ L+ +VF TRYLDL T ++VS YN  MKI F+ +  Y  V     K   T  Y+ +   DTF+++ +LI +  ++V  +HK   +E+ W+FS++LES+AILPQL+M++  G   ++T HY+FA+G+YRALYI NWI+RY TE    D I   AG +QT+ + DFFY+Y T+V++GK   LP
Sbjct:    1 MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLP 218

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BLAST of SMED30016113 vs. Ensembl Nematostella
Match: EDO48388 (ER lumen protein retaining receptor [Source:UniProtKB/TrEMBL;Acc:A7RJJ4])

HSP 1 Score: 311.612 bits (797), Expect = 2.147e-107
Identity = 147/211 (69.67%), Postives = 176/211 (83.41%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL+GDLSHL AII+LL KIWKTRSCAGVSGK+Q++F +VF+TRYLDLFT+FVS YN+ MK+I+++  + T++ +Y KF+ATY S  DTFRVEF+LIP   LA L NH+  +ME+LWTFSIYLES+AILPQLFMI+ TG AE+IT HYLFALG YRALYI NW+YRYY EG YD I IVAGCVQT  + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLVGDLSHLVAIILLLWKIWKTRSCAGVSGKSQMMFALVFSTRYLDLFTSFVSLYNSVMKVIYISCAFATLYLMYIKFKATYDSNHDTFRVEFLLIPVAGLACLVNHEFTIMEVLWTFSIYLESVAILPQLFMISKTGEAESITSHYLFALGAYRALYIANWVYRYYFEGFYDFIAIVAGCVQTALYCDFFYLYITKVLKGKSLKLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Medaka
Match: KDELR2 (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101157057])

HSP 1 Score: 307.375 bits (786), Expect = 1.930e-104
Identity = 148/212 (69.81%), Postives = 174/212 (82.08%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AIIILLLKIWKTRSCAG+SGK+QILF +VFTTRYLDL T+F+S YN++MK+I++   Y TV+ IY KFRATY    D+FRVEF+++P   LAVL NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:   60 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNSSMKVIYIGCSYATVYLIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 271

[Close]

BLAST of SMED30016113 vs. Ensembl Medaka
Match: kdelr2b (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101160362])

HSP 1 Score: 302.368 bits (773), Expect = 2.653e-103
Identity = 146/211 (69.19%), Postives = 172/211 (81.52%), Query Frame = -2

Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYVKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211

[Close]

BLAST of SMED30016113 vs. Ensembl Medaka
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:101155114])

HSP 1 Score: 295.434 bits (755), Expect = 1.907e-100
Identity = 137/213 (64.32%), Postives = 179/213 (84.04%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGK-DVILPV 874
            MN+FRL GD+SHL AIIILLLKIW++RSCAG+SGK+Q+LF IVFTTRYLDLFT F+S YNT MK++FL L Y TV+ IY +F+ T++S +D+FR+EF+L+P   L+ LEN+    +EILWTFSI+LES+AI+PQLFMIT TG AE+IT HYLF LG+YRALYI NW++RY+TEG +D I +V+G VQT+F++DFFYLY T+VL+G+  + LP+
Sbjct:    1 MNVFRLAGDVSHLVAIIILLLKIWRSRSCAGISGKSQVLFAIVFTTRYLDLFTIFISPYNTIMKVVFLALSYATVYLIYVRFKNTFNSENDSFRLEFLLVPVIGLSFLENYAFTPLEILWTFSIFLESVAIMPQLFMITKTGEAESITTHYLFFLGLYRALYIANWVWRYHTEGFFDQIAVVSGVVQTIFYIDFFYLYVTKVLRGRGKMTLPM 213

[Close]

BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000053522.1 (SMESG000053522.1)

HSP 1 Score: 425.246 bits (1092), Expect = 6.020e-152
Identity = 212/212 (100.00%), Postives = 212/212 (100.00%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV
Sbjct:    1 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 212

[Close]

BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 289.656 bits (740), Expect = 2.268e-98
Identity = 136/212 (64.15%), Postives = 171/212 (80.66%), Query Frame = -2

Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GD+SHL AIIILLLKIWKTRSC+G+SGK+QI+F +VFT RYLDLFT+FVS YN+ MK++FL   Y TV+ ++ KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP 
Sbjct:    1 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 212

[Close]

BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000073757.1 (SMESG000073757.1)

HSP 1 Score: 259.225 bits (661), Expect = 1.618e-86
Identity = 126/202 (62.38%), Postives = 157/202 (77.72%), Query Frame = -2

Query:  242 LSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 847
            +SHL AII+LL KIWK+RSCAG+SGK+QI+F +VF TRYLDLF  ++S YN  MK  F+     TV+FIY KF+ATY    D+FR+EFI++P   LAVL NHK   +EILWT+SIYLESLAILPQL++I+ TG AETIT HYLFALG+YRA YI+NW YR++ E  YD+I I +G +QT+ + DFFYLY T+VLKGK   LP
Sbjct:    1 MSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLP 202

[Close]

BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 220.32 bits (560), Expect = 8.744e-72
Identity = 104/173 (60.12%), Postives = 135/173 (78.03%), Query Frame = -2

Query:  242 LFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 760
            +F +VFT RYLDLFT+FVS YN+ MK++FL   Y TV+ ++ KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP
Sbjct:    1 MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 173

[Close]

BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 177.948 bits (450), Expect = 1.252e-55
Identity = 81/132 (61.36%), Postives = 103/132 (78.03%), Query Frame = -2

Query:  239 KFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 634
            KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP 
Sbjct:    4 KFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 135

The following BLAST results are available for this feature:

BLAST of SMED30016113 vs. Ensembl Human
BLAST of SMED30016113 vs. Ensembl Celegans
BLAST of SMED30016113 vs. Ensembl Fly
BLAST of SMED30016113 vs. Ensembl Zebrafish
BLAST of SMED30016113 vs. Ensembl Xenopus
BLAST of SMED30016113 vs. Ensembl Mouse
BLAST of SMED30016113 vs. UniProt/SwissProt
BLAST of SMED30016113 vs. TrEMBL
BLAST of SMED30016113 vs. Ensembl Cavefish
BLAST of SMED30016113 vs. Ensembl Sea Lamprey
BLAST of SMED30016113 vs. Ensembl Yeast
BLAST of SMED30016113 vs. Ensembl Nematostella
BLAST of SMED30016113 vs. Ensembl Medaka
BLAST of SMED30016113 vs. Planmine SMEST

BLAST of SMED30016113 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KDELR2	1.395e-103	68.25	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	7.964e-101	65.57	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR3	1.042e-94	65.67	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	1.978e-92	66.51	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	2.387e-63	63.76	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of SMED30016113 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
erd-2.1	2.986e-92	61.17	ER lumen protein-retaining receptor [Source:UniPr...	[more]
erd-2.2	6.490e-86	63.38	Putative ER lumen protein-retaining receptor C28H8...	[more]
erd-2.2	6.490e-86	63.38	Putative ER lumen protein-retaining receptor C28H8...	[more]

BLAST of SMED30016113 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
KdelR	2.000e-97	64.45	gene:FBgn0267330 transcript:FBtr0080021	[more]
KdelR	2.000e-97	64.45	gene:FBgn0267330 transcript:FBtr0080023	[more]
KdelR	2.000e-97	64.45	gene:FBgn0267330 transcript:FBtr0080022	[more]

BLAST of SMED30016113 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kdelr2a	2.882e-104	68.87	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr2b	3.327e-103	67.92	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr3	6.242e-96	63.38	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr3	6.242e-96	63.38	KDEL endoplasmic reticulum protein retention recep...	[more]
CABZ01075611.1	1.855e-54	60.14	pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDA...	[more]

BLAST of SMED30016113 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
kdelr2	7.091e-104	68.40	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr1	3.816e-102	67.77	KDEL endoplasmic reticulum protein retention recep...	[more]
stx1a	1.346e-91	66.34	syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753]	[more]

BLAST of SMED30016113 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kdelr2	2.371e-103	67.77	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr3	1.175e-98	64.62	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	1.548e-92	66.51	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	1.621e-63	63.76	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]
Kdelr1	4.102e-53	67.15	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote...	[more]

BLAST of SMED30016113 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5ZKX9\|ERD22_CHICK	1.951e-103	68.72	ER lumen protein-retaining receptor 2 OS=Gallus ga...	[more]
sp\|Q6PEH1\|ERD22_DANRE	2.176e-103	68.87	ER lumen protein-retaining receptor 2 OS=Danio rer...	[more]
sp\|Q5XHA2\|ERD21_XENTR	3.756e-103	68.40	ER lumen protein-retaining receptor 1 OS=Xenopus t...	[more]
sp\|P33947\|ERD22_HUMAN	6.701e-103	68.25	ER lumen protein-retaining receptor 2 OS=Homo sapi...	[more]
sp\|Q5U305\|ERD22_RAT	1.659e-102	67.77	ER lumen protein-retaining receptor 2 OS=Rattus no...	[more]

BLAST of SMED30016113 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3Q0JXJ0	3.484e-104	67.26	ER lumen protein-retaining receptor OS=Ciona intes...	[more]
Q8I7E2	5.265e-104	70.28	ER lumen protein-retaining receptor OS=Ciona intes...	[more]
A0A3Q0JUS8	5.295e-104	70.28	ER lumen protein-retaining receptor OS=Ciona intes...	[more]
A7RJJ4	1.553e-103	69.67	ER lumen protein-retaining receptor OS=Nematostell...	[more]
A0A3Q1JW37	2.894e-103	71.09	ER lumen protein-retaining receptor OS=Anabas test...	[more]

BLAST of SMED30016113 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KDELR2	2.666e-104	69.67	KDEL endoplasmic reticulum protein retention recep...	[more]
kdelr2a	6.745e-104	68.25	ER lumen protein-retaining receptor 2-like [Source...	[more]
KDELR3	1.019e-98	65.05	ER lumen protein-retaining receptor 3 [Source:NCBI...	[more]
ENSAMXT00000042346.1	2.969e-36	40.09	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000040094.1	8.918e-33	36.28	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of SMED30016113 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
KDELR1	9.478e-97	67.92	KDEL endoplasmic reticulum protein retention recep...	[more]
KDELR1	3.991e-94	67.77	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of SMED30016113 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
ERD2	2.700e-58	47.25	HDEL receptor; an integral membrane protein that b...	[more]

BLAST of SMED30016113 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO48388	2.147e-107	69.67	ER lumen protein retaining receptor [Source:UniPr...	[more]

BLAST of SMED30016113 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
KDELR2	1.930e-104	69.81	ER lumen protein-retaining receptor 2 [Source:NCBI...	[more]
kdelr2b	2.653e-103	69.19	ER lumen protein-retaining receptor 2 [Source:NCBI...	[more]
kdelr3	1.907e-100	64.32	KDEL endoplasmic reticulum protein retention recep...	[more]

BLAST of SMED30016113 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000053522.1	6.020e-152	100.00	SMESG000053522.1	[more]
SMESG000064394.1	2.268e-98	64.15	SMESG000064394.1	[more]
SMESG000073757.1	1.618e-86	62.38	SMESG000073757.1	[more]
SMESG000064394.1	8.744e-72	60.12	SMESG000064394.1	[more]
SMESG000064394.1	1.252e-55	61.36	SMESG000064394.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30016113 ID=SMED30016113|Name=SMED30016113|organism=Schmidtea mediterranea sexual|type=transcript|length=983bp
TTTATTCACCAACACAAGAGGCGATGCCCGCAAACATTCTGATGCAACTG
TCACGCATTCCGCATCAAACGCATGCACTTCTCACTCAGCCACCGCGAAC
GACGTCAGTAAGAACCATTTCCAAATTTATACATCATAATATGGGATCAG
TCCCGATACATTATTTCGGCATGCGACAGGGAGAAAATTGTGTCATGCAT
CAAGGCAGCAATACGATCTGTACAAATGTCCACATTTAAACCGGCAGAAT
GACGTCCTTGCCTTTTAGAACTCGAGTCGCGTATAAGTAGAAGAAATCGA
GGAAGAAAACCGTCTGGACACAGCCAGCCACAATTACGATCATGTCATAT
AATCCTTCTGTATAATATCGGTATATCCAGTTGATAATGTAGAGCGCCCG
ATAGATACCAAGCGCAAATAGGTAATGATATGTTATTGTCTCCGCAGATC
CTGTGTTCGTTATCATGAACAGCTGTGGCAAGATTGCCAAAGATTCGAGA
TATATTGAGAAGGTCCACAAAATCTCCATAAGATCTGATTTGTGATTCTC
TAACACCGCCAATGCAAAGGTTGGGATAAGAATGAATTCAACCCGGAACG
TGTCATCGACTGAATGGTAAGTTGCCCTGAATTTTCTGTATATAAAGAAA
ACAGTGGTGTAAATCAGGGTGAGGAAAATAATTTTCATAGCCGTGTTGTA
AGCAGATACAAAATTCGTAAACAGATCAAGATAGCGAGTTGTAAAAACGA
TTAGAAAAAGAATCTGAGTTTTTCCGGAGACTCCGGCACATGAGCGCGTT
TTCCAAATTTTCAGCAGCAAGATAATTATTGCCCCCAAATGGGACAGATC
ACCAATCAATCTAAATATATTCATTTAGACTCGAAATTGTATTTCAGTTT
GACGTGTTAAAACTTGAATATATTTATGACGCCTCAAGGTTAGAATAAAT
GCAAGAGGAAAATTAAAACAAATCTGAATAGTA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000418	head
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000133	ER_ret_rcpt

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0006621	protein retention in ER lumen

Vocabulary: **molecular function**
Term	Definition
GO:0046923	ER retention sequence binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000133	ER lumen protein retaining receptor	PRINTS	PR00660	ERLUMENR	coord: 156..174 score: 71.43 coord: 120..140 score: 73.13 coord: 31..51 score: 68.71 coord: 52..68 score: 62.18 coord: 184..199 score: 61.16 coord: 4..23 score: 67.86 coord: 142..156 score: 69.05
IPR000133	ER lumen protein retaining receptor	PFAM	PF00810	ER_lumen_recept	coord: 28..169 e-value: 2.0E-51 score: 174.7
IPR000133	ER lumen protein retaining receptor	PANTHER	PTHR10585	ER LUMEN PROTEIN RETAINING RECEPTOR	coord: 1..210
IPR000133	ER lumen protein retaining receptor	PROSITE	PS00951	ER_LUMEN_RECEPTOR_1	coord: 31..48
None	No IPR available	PANTHER	PTHR10585:SF37	ER LUMEN PROTEIN-RETAINING RECEPTOR 2	coord: 1..210
None	No IPR available	TMHMM	TMhelix		coord: 57..79
None	No IPR available	TMHMM	TMhelix		coord: 178..200
None	No IPR available	TMHMM	TMhelix		coord: 146..168