SMED30016113

Overview
NameSMED30016113
Smed IDSMED30016113
Length (bp)983
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30016113 (SMED30016113) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30016113 (SMED30016113) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30016113

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30016113h1SMcG0002047 Contig49190uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016113h1SMcG0002047 Contig49190newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30016113h1SMcG0002047 dd_Smed_v4_548_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30016113h1SMcG0002047 dd_Smed_v4_548_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30016113h1SMcG0002047 dd_Smed_v4_548_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30016113h1SMcG0002047 dd_Smed_v4_548_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30016113h1SMcG0002047 dd_Smed_v4_548_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30016113h1SMcG0002047 dd_Smed_v4_548_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016113h1SMcG0002047 Contig4711GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30016113h1SMcG0007492 Contig4711GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30016113h1SMcG0002047 OX_Smed_1.0.22806ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
neoblastSMED30016113h1SMcG0002047 SMED_00102_V2_1rGPL14150PMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Alignments
SMED30016113 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.003522:8021..9514 -4869
Homology
BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305])

HSP 1 Score: 303.908 bits (777), Expect = 1.395e-103
Identity = 144/211 (68.25%), Postives = 175/211 (82.94%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I+L   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 296.975 bits (759), Expect = 7.964e-101
Identity = 139/212 (65.57%), Postives = 173/212 (81.60%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR++GDLSHL A+I+LL KIW+++ C G+SGK+QILF +VFTTRYLDLFTNF+S YNT MK++FL   Y TV+ IY KFR T+ S +DTFR+EF+L+P   L+ LEN+   L+EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI RY TE  YD I +V+G VQT+F+ DFFYLY T+VLKGK + LP+
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPM 212          
BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306])

HSP 1 Score: 281.567 bits (719), Expect = 1.042e-94
Identity = 132/201 (65.67%), Postives = 164/201 (81.59%), Query Frame = -2
Query:  272 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATR 874
            MN+FR++GDLSHL A+I+LL KIW+++ C G+SGK+QILF +VFTTRYLDLFTNF+S YNT MK++FL   Y TV+ IY KFR T+ S +DTFR+EF+L+P   L+ LEN+   L+EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI RY TE  YD I +V+G VQT+F+ DFFYLY T+
Sbjct:    1 MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTK 201          
BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 275.404 bits (703), Expect = 1.978e-92
Identity = 141/212 (66.51%), Postives = 174/212 (82.08%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR +GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFT RYLDLFTN++S YNT MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. Ensembl Human
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 199.134 bits (505), Expect = 2.387e-63
Identity = 95/149 (63.76%), Postives = 118/149 (79.19%), Query Frame = -2
Query:  242 MKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 688
            MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 149          
BLAST of SMED30016113 vs. Ensembl Celegans
Match: erd-2.1 (ER lumen protein-retaining receptor [Source:UniProtKB/Swiss-Prot;Acc:P48583])

HSP 1 Score: 273.863 bits (699), Expect = 2.986e-92
Identity = 126/206 (61.17%), Postives = 166/206 (80.58%), Query Frame = -2
Query:  257 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGK 874
            MN+FR   D++H  AI++LLLKIWK+RSC G+SG++Q+LF +VF TRYLDLFTNF S YNTAMKI +L   + TV+ ++ KF+ATY   +D+FR+EF++IP+  LA+L NH+   ME++WTFSIYLE++AI+PQLFM++ TG+AETIT HYLFALG YR LYI+NW+YRYYTE  +D I +VAG VQTV + DFFYLY TRV++  
Sbjct:    1 MNLFRFTADVAHAIAIVVLLLKIWKSRSCEGISGRSQLLFALVFVTRYLDLFTNFFSFYNTAMKIFYLVASFGTVYLMWAKFKATYDRNNDSFRIEFLVIPSMILALLINHEFIFMEVMWTFSIYLEAVAIMPQLFMLSRTGNAETITAHYLFALGSYRFLYILNWVYRYYTESFFDPISVVAGIVQTVLYADFFYLYITRVIQSN 206          
BLAST of SMED30016113 vs. Ensembl Celegans
Match: erd-2.2 (Putative ER lumen protein-retaining receptor C28H8.4 [Source:UniProtKB/Swiss-Prot;Acc:Q09473])

HSP 1 Score: 257.684 bits (657), Expect = 6.490e-86
Identity = 135/213 (63.38%), Postives = 167/213 (78.40%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKG-KDVILPV 874
            MNIFR+  D+SHL AIIILLLKIWK+RSC+G+S ++QILF +VFT RYLDLF+ ++S YNT MKI FL   Y TV+ ++ KFR+TY    DTFRVE +++P   LA+L NH     E+LWTFSIYLE++AILPQLF++ +TGSAE IT HYLFALG YRALYI NWIYRYYTE  +D IV+VAG VQTV + DFFYLY TRV++  K + LP+
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELPI 213          
BLAST of SMED30016113 vs. Ensembl Celegans
Match: erd-2.2 (Putative ER lumen protein-retaining receptor C28H8.4 [Source:UniProtKB/Swiss-Prot;Acc:Q09473])

HSP 1 Score: 257.684 bits (657), Expect = 6.490e-86
Identity = 135/213 (63.38%), Postives = 167/213 (78.40%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKG-KDVILPV 874
            MNIFR+  D+SHL AIIILLLKIWK+RSC+G+S ++QILF +VFT RYLDLF+ ++S YNT MKI FL   Y TV+ ++ KFR+TY    DTFRVE +++P   LA+L NH     E+LWTFSIYLE++AILPQLF++ +TGSAE IT HYLFALG YRALYI NWIYRYYTE  +D IV+VAG VQTV + DFFYLY TRV++  K + LP+
Sbjct:    1 MNIFRISADMSHLLAIIILLLKIWKSRSCSGISARSQILFALVFTARYLDLFSTYISLYNTTMKITFLAATYATVYLMFFKFRSTYMRESDTFRVELLIVPAAILALLINHDFAPFELLWTFSIYLEAVAILPQLFLLQSTGSAEVITAHYLFALGSYRALYIFNWIYRYYTEDYFDPIVVVAGIVQTVLYADFFYLYVTRVVQTRKGMELPI 213          
BLAST of SMED30016113 vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080021)

HSP 1 Score: 287.345 bits (734), Expect = 2.000e-97
Identity = 136/211 (64.45%), Postives = 170/211 (80.57%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFR  GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ TRYLDLFT +VS YN+ MK++FL     TV+ +Y KF+ATY    D+FR+EF+L+P   L+++ NH+  +ME+LWTFSIYLES+AILPQLF+++ TG AE+IT HYLFALG YRALY++NW+YRY  E  YD+I I AG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211          
BLAST of SMED30016113 vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080023)

HSP 1 Score: 287.345 bits (734), Expect = 2.000e-97
Identity = 136/211 (64.45%), Postives = 170/211 (80.57%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFR  GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ TRYLDLFT +VS YN+ MK++FL     TV+ +Y KF+ATY    D+FR+EF+L+P   L+++ NH+  +ME+LWTFSIYLES+AILPQLF+++ TG AE+IT HYLFALG YRALY++NW+YRY  E  YD+I I AG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211          
BLAST of SMED30016113 vs. Ensembl Fly
Match: KdelR (gene:FBgn0267330 transcript:FBtr0080022)

HSP 1 Score: 287.345 bits (734), Expect = 2.000e-97
Identity = 136/211 (64.45%), Postives = 170/211 (80.57%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFR  GDLSH+ AIIILLLKIWKTRSCAG+SGK+QILF +V+ TRYLDLFT +VS YN+ MK++FL     TV+ +Y KF+ATY    D+FR+EF+L+P   L+++ NH+  +ME+LWTFSIYLES+AILPQLF+++ TG AE+IT HYLFALG YRALY++NW+YRY  E  YD+I I AG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFFYLYITKVLKGKKLQLP 211          
BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: kdelr2a (KDEL endoplasmic reticulum protein retention receptor 2a [Source:NCBI gene;Acc:373129])

HSP 1 Score: 305.064 bits (780), Expect = 2.882e-104
Identity = 146/212 (68.87%), Postives = 171/212 (80.66%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KFRATY    DTFR EF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: kdelr2b (KDEL endoplasmic reticulum protein retention receptor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-4189])

HSP 1 Score: 302.368 bits (773), Expect = 3.327e-103
Identity = 144/212 (67.92%), Postives = 173/212 (81.60%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   LA L NH    +EILWTFSIYLES++ILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNLFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTSMKVIYIACAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVSILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:393613])

HSP 1 Score: 283.878 bits (725), Expect = 6.242e-96
Identity = 135/213 (63.38%), Postives = 174/213 (81.69%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MNIFRL GD+ HL AIIIL LKIW+++SCAG+SGK+Q+LF +VFTTRYLDLFT+++SAYNT MK+++L L Y+TV  I+ +FR +Y S  D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYL  LG+YRALY+ NW++R++TEG YD I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 213          
BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:393613])

HSP 1 Score: 283.878 bits (725), Expect = 6.242e-96
Identity = 135/213 (63.38%), Postives = 174/213 (81.69%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MNIFRL GD+ HL AIIIL LKIW+++SCAG+SGK+Q+LF +VFTTRYLDLFT+++SAYNT MK+++L L Y+TV  I+ +FR +Y S  D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYL  LG+YRALY+ NW++R++TEG YD I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNIFRLSGDVCHLIAIIILFLKIWRSKSCAGISGKSQVLFALVFTTRYLDLFTSYISAYNTIMKVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 213          
BLAST of SMED30016113 vs. Ensembl Zebrafish
Match: CABZ01075611.1 (pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDARG00000104519.2 transcript:ENSDART00000165169.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01075611.1)

HSP 1 Score: 177.563 bits (449), Expect = 1.855e-54
Identity = 83/138 (60.14%), Postives = 109/138 (78.99%), Query Frame = -2
Query:  272 KIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATR 685
            ++++L L Y+TV  I+ +FR +Y S  D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYL  LG+YRALY+ NW++R++TEG YD I +V+G VQT+F+ DFFYLY TR
Sbjct:   38 QVVYLLLAYSTVGLIFFRFRNSYDSESDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITAHYLLFLGLYRALYLANWLWRFHTEGFYDQIAVVSGVVQTIFYCDFFYLYFTR 175          
BLAST of SMED30016113 vs. Ensembl Xenopus
Match: kdelr2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:496456])

HSP 1 Score: 304.294 bits (778), Expect = 7.091e-104
Identity = 145/212 (68.40%), Postives = 175/212 (82.55%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFR +GD+SHL AI+ILLLKIWK+RSCAG+SGK+Q+LF IVFTTRYLDLFTNF+S YNT+MK++++   Y T++ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALGIYRALY+ NWI+RY  EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRFLGDISHLSAILILLLKIWKSRSCAGISGKSQLLFAIVFTTRYLDLFTNFISLYNTSMKMVYVASSYATIWMIYSKFKATYDGNHDTFRVEFLIVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGIYRALYLFNWIWRYQFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. Ensembl Xenopus
Match: kdelr1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:NCBI gene;Acc:395012])

HSP 1 Score: 300.056 bits (767), Expect = 3.816e-102
Identity = 143/211 (67.77%), Postives = 173/211 (81.99%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MN+FRL GDLSHL AIIILLLKIWK+RSCAG+SGK+Q+LF +VFTTRYLDL T+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+VL NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+RY  EG +D+I IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNVFRLSGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTSMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSVLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRYSFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Xenopus
Match: stx1a (syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753])

HSP 1 Score: 274.248 bits (700), Expect = 1.346e-91
Identity = 136/205 (66.34%), Postives = 169/205 (82.44%), Query Frame = -2
Query:  239 GDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 853
            GD+SHL AIIILLLK+WK++SCAG+SGK+Q+LF +VFTTRYLDLFT F+SAYNT MKI+FL   Y TV+ IY KFR  Y S +DTFR+EF+L+P   L+ LEN++   +EILWTFSIYLES+AILPQLFMI+ TG AE+IT HYLF LG+YR LY+ NWI+RY+TE  YD I +V+G VQT+F+ DFFYLY T+VLKGK + LP+
Sbjct:   37 GDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISAYNTVMKIVFLVCAYVTVYLIYGKFRKAYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILWTFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIAVVSGVVQTIFYFDFFYLYITKVLKGKKLSLPM 241          
BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr2 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 [Source:MGI Symbol;Acc:MGI:1914163])

HSP 1 Score: 302.753 bits (774), Expect = 2.371e-103
Identity = 143/211 (67.77%), Postives = 175/211 (82.94%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr3 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 [Source:MGI Symbol;Acc:MGI:2145953])

HSP 1 Score: 290.812 bits (743), Expect = 1.175e-98
Identity = 137/212 (64.62%), Postives = 172/212 (81.13%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR++GDLSHL A+I+LL+KIW+++SCAG+SGK+QILF +VFTTRYLDLF+NF+S YNT MK++FL   Y TV+ IY KFR T+   +DTFR+EF+L+P   L+ L N+    ME+LWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YR LY+ NWI RY TE  YD I +V+G VQT+F+ DFFYLY T+VLKGK + LPV
Sbjct:    1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYNTVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPVTGLSFLVNYSYTPMEVLWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQISVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPV 212          
BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 275.404 bits (703), Expect = 1.548e-92
Identity = 141/212 (66.51%), Postives = 174/212 (82.08%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FR +GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFT RYLDLFTN++S YNT MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 199.134 bits (505), Expect = 1.621e-63
Identity = 95/149 (63.76%), Postives = 118/149 (79.19%), Query Frame = -2
Query:  242 MKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 688
            MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 149          
BLAST of SMED30016113 vs. Ensembl Mouse
Match: Kdelr1 (KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 [Source:MGI Symbol;Acc:MGI:1915387])

HSP 1 Score: 172.17 bits (435), Expect = 4.102e-53
Identity = 92/137 (67.15%), Postives = 114/137 (83.21%), Query Frame = -2
Query:  464 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFM 874
            MN+FR +GDLSHL AII+LLLKIWK+RSCAG+SGK+Q+LF +VFT RYLDLFTN++S YNT MK++++   +TTV+ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM
Sbjct:    1 MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFM 137          
BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q5ZKX9|ERD22_CHICK (ER lumen protein-retaining receptor 2 OS=Gallus gallus OX=9031 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 305.064 bits (780), Expect = 1.951e-103
Identity = 145/211 (68.72%), Postives = 175/211 (82.94%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+RYY EG +D+I +VAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLIVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRYYFEGFFDLIAVVAGVVQTVLYCDFFYLYVTKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q6PEH1|ERD22_DANRE (ER lumen protein-retaining receptor 2 OS=Danio rerio OX=7955 GN=kdelr2 PE=2 SV=1)

HSP 1 Score: 305.064 bits (780), Expect = 2.176e-103
Identity = 146/212 (68.87%), Postives = 171/212 (80.66%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KFRATY    DTFR EF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYAKFRATYDGNHDTFRAEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q5XHA2|ERD21_XENTR (ER lumen protein-retaining receptor 1 OS=Xenopus tropicalis OX=8364 GN=kdelr1 PE=2 SV=1)

HSP 1 Score: 304.294 bits (778), Expect = 3.756e-103
Identity = 145/212 (68.40%), Postives = 175/212 (82.55%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFR +GD+SHL AI+ILLLKIWK+RSCAG+SGK+Q+LF IVFTTRYLDLFTNF+S YNT+MK++++   Y T++ IY KF+ATY    DTFRVEF+++PT  LA L NH    +EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALGIYRALY+ NWI+RY  EG +D+I IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNIFRFLGDISHLSAILILLLKIWKSRSCAGISGKSQLLFAIVFTTRYLDLFTNFISLYNTSMKMVYVASSYATIWMIYSKFKATYDGNHDTFRVEFLIVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGIYRALYLFNWIWRYQFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|P33947|ERD22_HUMAN (ER lumen protein-retaining receptor 2 OS=Homo sapiens OX=9606 GN=KDELR2 PE=1 SV=1)

HSP 1 Score: 303.908 bits (777), Expect = 6.701e-103
Identity = 144/211 (68.25%), Postives = 175/211 (82.94%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I+L   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. UniProt/SwissProt
Match: sp|Q5U305|ERD22_RAT (ER lumen protein-retaining receptor 2 OS=Rattus norvegicus OX=10116 GN=Kdelr2 PE=2 SV=1)

HSP 1 Score: 302.753 bits (774), Expect = 1.659e-102
Identity = 143/211 (67.77%), Postives = 175/211 (82.94%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AI+ILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDLFT+F+S YNT+MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   L+ L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY++NWI+R+Y EG +D+I +VAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. TrEMBL
Match: A0A3Q0JXJ0 (ER lumen protein-retaining receptor OS=Ciona intestinalis OX=7719 GN=erd2 PE=3 SV=1)

HSP 1 Score: 314.694 bits (805), Expect = 3.484e-104
Identity = 150/223 (67.26%), Postives = 180/223 (80.72%), Query Frame = -2
Query:  239 TRQTEIQFRV*MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 907
            T +  +  ++ MNIFRL GDLSHL AII+LLLKIWKTRSCAG+SGK+QILF +VFTTRYLDLFTNF+S YNT MK+I+L   Y TV+ IY KF+ATY    DTFR EF+++P   LA L NH+   +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLFALG+YRALY+INWI+RYY E  +D+I IVAGCVQT+ + DFFYLY T+VL+GK + LP 
Sbjct:   22 TAKCILNTKIRMNIFRLAGDLSHLAAIIVLLLKIWKTRSCAGISGKSQILFALVFTTRYLDLFTNFISPYNTVMKMIYLGCAYATVYLIYMKFKATYDGNHDTFRAEFLVVPVGGLAFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFALGMYRALYLINWIWRYYFENFFDLIAIVAGCVQTILYCDFFYLYITKVLQGKKLSLPA 244          
BLAST of SMED30016113 vs. TrEMBL
Match: Q8I7E2 (ER lumen protein-retaining receptor OS=Ciona intestinalis OX=7719 GN=erd2 PE=2 SV=1)

HSP 1 Score: 312.768 bits (800), Expect = 5.265e-104
Identity = 149/212 (70.28%), Postives = 175/212 (82.55%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AII+LLLKIWKTRSCAG+SGK+QILF +VFTTRYLDLFTNF+S YNT MK+I+L   Y TV+ IY KF+ATY    DTFR EF+++P   LA L NH+   +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLFALG+YRALY+INWI+RYY E  +D+I IVAGCVQT+ + DFFYLY T+VL+GK + LP 
Sbjct:    1 MNIFRLAGDLSHLAAIIVLLLKIWKTRSCAGISGKSQILFALVFTTRYLDLFTNFISPYNTVMKMIYLGCAYATVYLIYMKFKATYDGNHDTFRAEFLVVPVGGLAFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFALGMYRALYLINWIWRYYFENFFDLIAIVAGCVQTILYCDFFYLYITKVLQGKKLSLPA 212          
BLAST of SMED30016113 vs. TrEMBL
Match: A0A3Q0JUS8 (ER lumen protein-retaining receptor OS=Ciona intestinalis OX=7719 GN=erd2 PE=3 SV=1)

HSP 1 Score: 313.153 bits (801), Expect = 5.295e-104
Identity = 149/212 (70.28%), Postives = 175/212 (82.55%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AII+LLLKIWKTRSCAG+SGK+QILF +VFTTRYLDLFTNF+S YNT MK+I+L   Y TV+ IY KF+ATY    DTFR EF+++P   LA L NH+   +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLFALG+YRALY+INWI+RYY E  +D+I IVAGCVQT+ + DFFYLY T+VL+GK + LP 
Sbjct:    4 MNIFRLAGDLSHLAAIIVLLLKIWKTRSCAGISGKSQILFALVFTTRYLDLFTNFISPYNTVMKMIYLGCAYATVYLIYMKFKATYDGNHDTFRAEFLVVPVGGLAFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFALGMYRALYLINWIWRYYFENFFDLIAIVAGCVQTILYCDFFYLYITKVLQGKKLSLPA 215          
BLAST of SMED30016113 vs. TrEMBL
Match: A7RJJ4 (ER lumen protein-retaining receptor OS=Nematostella vectensis OX=45351 GN=v1g236409 PE=3 SV=1)

HSP 1 Score: 311.612 bits (797), Expect = 1.553e-103
Identity = 147/211 (69.67%), Postives = 176/211 (83.41%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL+GDLSHL AII+LL KIWKTRSCAGVSGK+Q++F +VF+TRYLDLFT+FVS YN+ MK+I+++  + T++ +Y KF+ATY S  DTFRVEF+LIP   LA L NH+  +ME+LWTFSIYLES+AILPQLFMI+ TG AE+IT HYLFALG YRALYI NW+YRYY EG YD I IVAGCVQT  + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLVGDLSHLVAIILLLWKIWKTRSCAGVSGKSQMMFALVFSTRYLDLFTSFVSLYNSVMKVIYISCAFATLYLMYIKFKATYDSNHDTFRVEFLLIPVAGLACLVNHEFTIMEVLWTFSIYLESVAILPQLFMISKTGEAESITSHYLFALGAYRALYIANWVYRYYFEGFYDFIAIVAGCVQTALYCDFFYLYITKVLKGKSLKLP 211          
BLAST of SMED30016113 vs. TrEMBL
Match: A0A3Q1JW37 (ER lumen protein-retaining receptor OS=Anabas testudineus OX=64144 PE=3 SV=1)

HSP 1 Score: 310.842 bits (795), Expect = 2.894e-103
Identity = 150/211 (71.09%), Postives = 174/211 (82.46%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRLIGDLSHL AIIILLLKIWK+RSCAG+SGK+QILF IVFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KFRATY    D+FRVEF+++P   LAVL NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQTV + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLIGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFAIVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSFLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTVLYCDFFYLYVTKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Cavefish
Match: KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2 [Source:NCBI gene;Acc:103025946])

HSP 1 Score: 305.064 bits (780), Expect = 2.666e-104
Identity = 147/211 (69.67%), Postives = 173/211 (81.99%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWK+RSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+INWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLINWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Cavefish
Match: kdelr2a (ER lumen protein-retaining receptor 2-like [Source:NCBI gene;Acc:103040303])

HSP 1 Score: 303.908 bits (777), Expect = 6.745e-104
Identity = 144/211 (68.25%), Postives = 173/211 (81.99%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWKTRSCAG+SGK+QILF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KF+ATY    DTFR+EF+++P   LA L NH    +EI+WTFSIYLES+AILPQLF+I+ TG AETIT HYLF+LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLAGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTCMKVIYIGCAYATVYLIYMKFKATYDGNHDTFRIEFLIVPVGGLAFLVNHDFSPLEIMWTFSIYLESVAILPQLFLISKTGEAETITTHYLFSLGVYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Cavefish
Match: KDELR3 (ER lumen protein-retaining receptor 3 [Source:NCBI gene;Acc:103035602])

HSP 1 Score: 290.812 bits (743), Expect = 1.019e-98
Identity = 134/206 (65.05%), Postives = 170/206 (82.52%), Query Frame = -2
Query:  257 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGK 874
            MN+FRL GD+SHL AII+L LKIW+++SCAG+SGK+Q+LF +VFTTRYLDLFT F+S YNT MK++FL L Y TV+ IY +FR +Y S +D+FRVEF+L+P   L+ LEN+    +EILWTFSIYLES+AILPQLFMIT TG AE+IT HYLF LG+YRALY+ NW++RY+TE  +D I +V+G VQT+F+ DFFYLY TRVL+G 
Sbjct:    1 MNVFRLCGDVSHLVAIILLFLKIWRSKSCAGISGKSQVLFAVVFTTRYLDLFTGFISIYNTVMKVVFLVLAYATVYLIYLRFRNSYDSENDSFRVEFLLVPVAGLSFLENYAFTPLEILWTFSIYLESVAILPQLFMITKTGEAESITTHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGS 206          
BLAST of SMED30016113 vs. Ensembl Cavefish
Match: ENSAMXT00000042346.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000042346.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.568 bits (327), Expect = 2.969e-36
Identity = 89/222 (40.09%), Postives = 119/222 (53.60%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRY-LDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYR--KFRATYHSVDDTFRVEFILIPTFALAVLEN-----HKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETI-TYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MN+FRL GD+S    + + L         AG+SGK+Q+   +  +    L   T F+S YNT MK+  L  +   + FIY    FR +Y S    F           L+ LE             ILWTFSIYLES+           TG AE+    HYLF LG+YRALY+ NW++RY+TE  +D I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNVFRLCGDVSAFSCLCVCLCVC------AGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGCLPGVGIPLQFIYSTCAFRNSYDS-GMHFISGGSCCSVAGLSFLEKLTPSTPTGGNTPILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 204          
BLAST of SMED30016113 vs. Ensembl Cavefish
Match: ENSAMXT00000040094.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002328.1:56753:63811:-1 gene:ENSAMXG00000035881.1 transcript:ENSAMXT00000040094.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.553 bits (301), Expect = 8.918e-33
Identity = 78/215 (36.28%), Postives = 106/215 (49.30%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTR-YLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETI-TYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVI-LPV 874
            MN+FRL GD+S     + L +       CAG+SGK+Q+   +  +    L   T F+S YNT MK+      +                                            +ILWTFSIYLES+           TG AE+    HYLF LG+YRALY+ NW++RY+TE  +D I +V+G VQT+F+ DFFYLY TRVL+G   + LP+
Sbjct:    1 MNVFRLCGDVSAFSLCVCLCV-------CAGISGKSQVAVCLWCSPHGILTCSTGFISIYNTVMKVGKHKHTHKHH--------------------TQHTHTHTPHTHTHTTTHPHSQILWTFSIYLESV-----------TGEAESYHQRHYLFFLGLYRALYLANWVWRYHTESFFDQIAVVSGVVQTIFYCDFFYLYFTRVLRGSGKMSLPM 177          
BLAST of SMED30016113 vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 283.878 bits (725), Expect = 9.478e-97
Identity = 144/212 (67.92%), Postives = 178/212 (83.96%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MN+FRL GDLSHL AIIILL+KIWKTRSCAG+SGK+QILF +VFTTRYLDLFT F+S YNT+MK++++   Y T++ IY KF+ATY   +DTFRVEF+++P   L+VL NH   L+EILWTFSIYLES+AILPQLF+++ TG AETIT HYLFALG+YRALY++NWI+RYY EG +D+I IVAG VQT+ + DFFYLY T+VLKGK + LP 
Sbjct:    1 MNVFRLTGDLSHLLAIIILLIKIWKTRSCAGISGKSQILFALVFTTRYLDLFTTFISIYNTSMKVVYMACAYATLWMIYHKFKATYDGNNDTFRVEFLVVPIGGLSVLVNHDFSLLEILWTFSIYLESVAILPQLFLVSKTGEAETITSHYLFALGLYRALYLLNWIWRYYFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA 212          
BLAST of SMED30016113 vs. Ensembl Sea Lamprey
Match: KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304])

HSP 1 Score: 277.33 bits (708), Expect = 3.991e-94
Identity = 143/211 (67.77%), Postives = 175/211 (82.94%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MN+FRL GDLSHL AIIILLLKIWKTRSCAG+SGK+QILF +VFTTRYLDL TN++S YNT MK+I++   Y TV+ IY KF+ATY S  DTFRVEF+++P   L+++ NH   ++EILWTFSIYLES+AILPQLFM++ TG AETIT HYLFALG+YR LY+ NWI+RY+ EG +D+I IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNVFRLAGDLSHLLAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTNYISLYNTTMKVIYIGCSYATVWMIYSKFKATYDSNHDTFRVEFLVLPVALLSLVVNHDYSVVEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYFAEGFFDLIAIVAGLVQTILYCDFFYLYITKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Yeast
Match: ERD2 (HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins [Source:SGD;Acc:S000000136])

HSP 1 Score: 185.652 bits (470), Expect = 2.700e-58
Identity = 103/218 (47.25%), Postives = 147/218 (67.43%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFT-NFVSAYNTAMKIIFL-TLIYTTVFFIYRKFRAT--YHSV--DDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLY-DMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MN FR++GDLSHL +I+IL+  I  TR   G+S KTQ L+ +VF TRYLDL T ++VS YN  MKI F+ +  Y  V     K   T  Y+ +   DTF+++ +LI +  ++V  +HK   +E+ W+FS++LES+AILPQL+M++  G   ++T HY+FA+G+YRALYI NWI+RY TE    D I   AG +QT+ + DFFY+Y T+V++GK   LP
Sbjct:    1 MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLP 218          
BLAST of SMED30016113 vs. Ensembl Nematostella
Match: EDO48388 (ER lumen protein retaining receptor [Source:UniProtKB/TrEMBL;Acc:A7RJJ4])

HSP 1 Score: 311.612 bits (797), Expect = 2.147e-107
Identity = 147/211 (69.67%), Postives = 176/211 (83.41%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL+GDLSHL AII+LL KIWKTRSCAGVSGK+Q++F +VF+TRYLDLFT+FVS YN+ MK+I+++  + T++ +Y KF+ATY S  DTFRVEF+LIP   LA L NH+  +ME+LWTFSIYLES+AILPQLFMI+ TG AE+IT HYLFALG YRALYI NW+YRYY EG YD I IVAGCVQT  + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLVGDLSHLVAIILLLWKIWKTRSCAGVSGKSQMMFALVFSTRYLDLFTSFVSLYNSVMKVIYISCAFATLYLMYIKFKATYDSNHDTFRVEFLLIPVAGLACLVNHEFTIMEVLWTFSIYLESVAILPQLFMISKTGEAESITSHYLFALGAYRALYIANWVYRYYFEGFYDFIAIVAGCVQTALYCDFFYLYITKVLKGKSLKLP 211          
BLAST of SMED30016113 vs. Ensembl Medaka
Match: KDELR2 (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101157057])

HSP 1 Score: 307.375 bits (786), Expect = 1.930e-104
Identity = 148/212 (69.81%), Postives = 174/212 (82.08%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GDLSHL AIIILLLKIWKTRSCAG+SGK+QILF +VFTTRYLDL T+F+S YN++MK+I++   Y TV+ IY KFRATY    D+FRVEF+++P   LAVL NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQTV + DFFYLY T+VLKGK + LP 
Sbjct:   60 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNSSMKVIYIGCSYATVYLIYMKFRATYDGNHDSFRVEFLVVPVGGLAVLINHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFCLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA 271          
BLAST of SMED30016113 vs. Ensembl Medaka
Match: kdelr2b (ER lumen protein-retaining receptor 2 [Source:NCBI gene;Acc:101160362])

HSP 1 Score: 302.368 bits (773), Expect = 2.653e-103
Identity = 146/211 (69.19%), Postives = 172/211 (81.52%), Query Frame = -2
Query:  242 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 874
            MNIFRL GDLSHL AIIILLLKIWKTRSCAG+SGK+Q+LF +VFTTRYLDL T+F+S YNT MK+I++   Y TV+ IY KF+ATY    DTFRVEF+++P   LA L NH    +EILWTFSIYLES+AILPQLFMI+ TG AETIT HYLF LG+YRALY+ NWI+R+Y EG +DMI IVAG VQT+ + DFFYLY T+VLKGK + LP
Sbjct:    1 MNIFRLTGDLSHLAAIIILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLLTSFISLYNTTMKVIYIGCAYATVYLIYVKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLP 211          
BLAST of SMED30016113 vs. Ensembl Medaka
Match: kdelr3 (KDEL endoplasmic reticulum protein retention receptor 3 [Source:NCBI gene;Acc:101155114])

HSP 1 Score: 295.434 bits (755), Expect = 1.907e-100
Identity = 137/213 (64.32%), Postives = 179/213 (84.04%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGK-DVILPV 874
            MN+FRL GD+SHL AIIILLLKIW++RSCAG+SGK+Q+LF IVFTTRYLDLFT F+S YNT MK++FL L Y TV+ IY +F+ T++S +D+FR+EF+L+P   L+ LEN+    +EILWTFSI+LES+AI+PQLFMIT TG AE+IT HYLF LG+YRALYI NW++RY+TEG +D I +V+G VQT+F++DFFYLY T+VL+G+  + LP+
Sbjct:    1 MNVFRLAGDVSHLVAIIILLLKIWRSRSCAGISGKSQVLFAIVFTTRYLDLFTIFISPYNTIMKVVFLALSYATVYLIYVRFKNTFNSENDSFRLEFLLVPVIGLSFLENYAFTPLEILWTFSIFLESVAIMPQLFMITKTGEAESITTHYLFFLGLYRALYIANWVWRYHTEGFFDQIAVVSGVVQTIFYIDFFYLYVTKVLRGRGKMTLPM 213          
BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000053522.1 (SMESG000053522.1)

HSP 1 Score: 425.246 bits (1092), Expect = 6.020e-152
Identity = 212/212 (100.00%), Postives = 212/212 (100.00%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV
Sbjct:    1 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 212          
BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 289.656 bits (740), Expect = 2.268e-98
Identity = 136/212 (64.15%), Postives = 171/212 (80.66%), Query Frame = -2
Query:  239 MNIFRLIGDLSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 874
            MNIFRL GD+SHL AIIILLLKIWKTRSC+G+SGK+QI+F +VFT RYLDLFT+FVS YN+ MK++FL   Y TV+ ++ KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP 
Sbjct:    1 MNIFRLAGDMSHLVAIIILLLKIWKTRSCSGISGKSQIMFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 212          
BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000073757.1 (SMESG000073757.1)

HSP 1 Score: 259.225 bits (661), Expect = 1.618e-86
Identity = 126/202 (62.38%), Postives = 157/202 (77.72%), Query Frame = -2
Query:  242 LSHLGAIIILLLKIWKTRSCAGVSGKTQILFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 847
            +SHL AII+LL KIWK+RSCAG+SGK+QI+F +VF TRYLDLF  ++S YN  MK  F+     TV+FIY KF+ATY    D+FR+EFI++P   LAVL NHK   +EILWT+SIYLESLAILPQL++I+ TG AETIT HYLFALG+YRA YI+NW YR++ E  YD+I I +G +QT+ + DFFYLY T+VLKGK   LP
Sbjct:    1 MSHLIAIILLLNKIWKSRSCAGLSGKSQIMFAVVFFTRYLDLFLVYISLYNVLMKAFFIISSLLTVYFIYFKFKATYDLNHDSFRLEFIMVPLGGLAVLINHKFSFVEILWTYSIYLESLAILPQLYLISKTGEAETITSHYLFALGVYRAFYILNWTYRFFVEDFYDLIAIFSGIIQTILYCDFFYLYMTKVLKGKAFTLP 202          
BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 220.32 bits (560), Expect = 8.744e-72
Identity = 104/173 (60.12%), Postives = 135/173 (78.03%), Query Frame = -2
Query:  242 LFLIVFTTRYLDLFTNFVSAYNTAMKIIFLTLIYTTVFFIYRKFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILP 760
            +F +VFT RYLDLFT+FVS YN+ MK++FL   Y TV+ ++ KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP
Sbjct:    1 MFALVFTARYLDLFTSFVSIYNSVMKVLFLLGTYITVYLMWFKFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLP 173          
BLAST of SMED30016113 vs. Planmine SMEST
Match: SMESG000064394.1 (SMESG000064394.1)

HSP 1 Score: 177.948 bits (450), Expect = 1.252e-55
Identity = 81/132 (61.36%), Postives = 103/132 (78.03%), Query Frame = -2
Query:  239 KFRATYHSVDDTFRVEFILIPTFALAVLENHKSDLMEILWTFSIYLESLAILPQLFMITNTGSAETITYHYLFALGIYRALYIINWIYRYYTEGLYDMIVIVAGCVQTVFFLDFFYLYATRVLKGKDVILPV 634
            KF+AT  S  DTFR EF++ P   LA++ NH    +EI WTFSIY+E++AILPQLF+I+ TG AE+IT HYLFALG YRALYI+NWIYRYY E  +D+I +V+GCVQT+ + DFFYLY T+VLKG+ + LP 
Sbjct:    4 KFKATNDSNHDTFRFEFLIGPCAILAIIVNHDFSFLEIFWTFSIYMEAVAILPQLFLISKTGEAESITSHYLFALGSYRALYILNWIYRYYGENFFDLIAVVSGCVQTILYCDFFYLYITKVLKGRKIRLPA 135          
The following BLAST results are available for this feature:
BLAST of SMED30016113 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KDELR21.395e-10368.25KDEL endoplasmic reticulum protein retention recep... [more]
KDELR37.964e-10165.57KDEL endoplasmic reticulum protein retention recep... [more]
KDELR31.042e-9465.67KDEL endoplasmic reticulum protein retention recep... [more]
KDELR11.978e-9266.51KDEL endoplasmic reticulum protein retention recep... [more]
KDELR12.387e-6363.76KDEL endoplasmic reticulum protein retention recep... [more]
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BLAST of SMED30016113 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
erd-2.12.986e-9261.17ER lumen protein-retaining receptor [Source:UniPr... [more]
erd-2.26.490e-8663.38Putative ER lumen protein-retaining receptor C28H8... [more]
erd-2.26.490e-8663.38Putative ER lumen protein-retaining receptor C28H8... [more]
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BLAST of SMED30016113 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
KdelR2.000e-9764.45gene:FBgn0267330 transcript:FBtr0080021[more]
KdelR2.000e-9764.45gene:FBgn0267330 transcript:FBtr0080023[more]
KdelR2.000e-9764.45gene:FBgn0267330 transcript:FBtr0080022[more]
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BLAST of SMED30016113 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdelr2a2.882e-10468.87KDEL endoplasmic reticulum protein retention recep... [more]
kdelr2b3.327e-10367.92KDEL endoplasmic reticulum protein retention recep... [more]
kdelr36.242e-9663.38KDEL endoplasmic reticulum protein retention recep... [more]
kdelr36.242e-9663.38KDEL endoplasmic reticulum protein retention recep... [more]
CABZ01075611.11.855e-5460.14pep chromosome:GRCz11:3:301479:302222:1 gene:ENSDA... [more]
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BLAST of SMED30016113 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
kdelr27.091e-10468.40KDEL endoplasmic reticulum protein retention recep... [more]
kdelr13.816e-10267.77KDEL endoplasmic reticulum protein retention recep... [more]
stx1a1.346e-9166.34syntaxin 1A [Source:Xenbase;Acc:XB-GENE-976753][more]
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BLAST of SMED30016113 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kdelr22.371e-10367.77KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr31.175e-9864.62KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr11.548e-9266.51KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr11.621e-6363.76KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
Kdelr14.102e-5367.15KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum prote... [more]
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BLAST of SMED30016113 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5ZKX9|ERD22_CHICK1.951e-10368.72ER lumen protein-retaining receptor 2 OS=Gallus ga... [more]
sp|Q6PEH1|ERD22_DANRE2.176e-10368.87ER lumen protein-retaining receptor 2 OS=Danio rer... [more]
sp|Q5XHA2|ERD21_XENTR3.756e-10368.40ER lumen protein-retaining receptor 1 OS=Xenopus t... [more]
sp|P33947|ERD22_HUMAN6.701e-10368.25ER lumen protein-retaining receptor 2 OS=Homo sapi... [more]
sp|Q5U305|ERD22_RAT1.659e-10267.77ER lumen protein-retaining receptor 2 OS=Rattus no... [more]
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BLAST of SMED30016113 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3Q0JXJ03.484e-10467.26ER lumen protein-retaining receptor OS=Ciona intes... [more]
Q8I7E25.265e-10470.28ER lumen protein-retaining receptor OS=Ciona intes... [more]
A0A3Q0JUS85.295e-10470.28ER lumen protein-retaining receptor OS=Ciona intes... [more]
A7RJJ41.553e-10369.67ER lumen protein-retaining receptor OS=Nematostell... [more]
A0A3Q1JW372.894e-10371.09ER lumen protein-retaining receptor OS=Anabas test... [more]
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BLAST of SMED30016113 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KDELR22.666e-10469.67KDEL endoplasmic reticulum protein retention recep... [more]
kdelr2a6.745e-10468.25ER lumen protein-retaining receptor 2-like [Source... [more]
KDELR31.019e-9865.05ER lumen protein-retaining receptor 3 [Source:NCBI... [more]
ENSAMXT00000042346.12.969e-3640.09pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000040094.18.918e-3336.28pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of SMED30016113 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
KDELR19.478e-9767.92KDEL endoplasmic reticulum protein retention recep... [more]
KDELR13.991e-9467.77KDEL endoplasmic reticulum protein retention recep... [more]
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BLAST of SMED30016113 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ERD22.700e-5847.25HDEL receptor; an integral membrane protein that b... [more]
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BLAST of SMED30016113 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO483882.147e-10769.67ER lumen protein retaining receptor [Source:UniPr... [more]
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BLAST of SMED30016113 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
KDELR21.930e-10469.81ER lumen protein-retaining receptor 2 [Source:NCBI... [more]
kdelr2b2.653e-10369.19ER lumen protein-retaining receptor 2 [Source:NCBI... [more]
kdelr31.907e-10064.32KDEL endoplasmic reticulum protein retention recep... [more]
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BLAST of SMED30016113 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053522.16.020e-152100.00SMESG000053522.1[more]
SMESG000064394.12.268e-9864.15SMESG000064394.1[more]
SMESG000073757.11.618e-8662.38SMESG000073757.1[more]
SMESG000064394.18.744e-7260.12SMESG000064394.1[more]
SMESG000064394.11.252e-5561.36SMESG000064394.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016113 ID=SMED30016113|Name=SMED30016113|organism=Schmidtea mediterranea sexual|type=transcript|length=983bp
TTTATTCACCAACACAAGAGGCGATGCCCGCAAACATTCTGATGCAACTG
TCACGCATTCCGCATCAAACGCATGCACTTCTCACTCAGCCACCGCGAAC
GACGTCAGTAAGAACCATTTCCAAATTTATACATCATAATATGGGATCAG
TCCCGATACATTATTTCGGCATGCGACAGGGAGAAAATTGTGTCATGCAT
CAAGGCAGCAATACGATCTGTACAAATGTCCACATTTAAACCGGCAGAAT
GACGTCCTTGCCTTTTAGAACTCGAGTCGCGTATAAGTAGAAGAAATCGA
GGAAGAAAACCGTCTGGACACAGCCAGCCACAATTACGATCATGTCATAT
AATCCTTCTGTATAATATCGGTATATCCAGTTGATAATGTAGAGCGCCCG
ATAGATACCAAGCGCAAATAGGTAATGATATGTTATTGTCTCCGCAGATC
CTGTGTTCGTTATCATGAACAGCTGTGGCAAGATTGCCAAAGATTCGAGA
TATATTGAGAAGGTCCACAAAATCTCCATAAGATCTGATTTGTGATTCTC
TAACACCGCCAATGCAAAGGTTGGGATAAGAATGAATTCAACCCGGAACG
TGTCATCGACTGAATGGTAAGTTGCCCTGAATTTTCTGTATATAAAGAAA
ACAGTGGTGTAAATCAGGGTGAGGAAAATAATTTTCATAGCCGTGTTGTA
AGCAGATACAAAATTCGTAAACAGATCAAGATAGCGAGTTGTAAAAACGA
TTAGAAAAAGAATCTGAGTTTTTCCGGAGACTCCGGCACATGAGCGCGTT
TTCCAAATTTTCAGCAGCAAGATAATTATTGCCCCCAAATGGGACAGATC
ACCAATCAATCTAAATATATTCATTTAGACTCGAAATTGTATTTCAGTTT
GACGTGTTAAAACTTGAATATATTTATGACGCCTCAAGGTTAGAATAAAT
GCAAGAGGAAAATTAAAACAAATCTGAATAGTA
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000418head
PLANA:0000429neoblast
PLANA:0002032epidermal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR000133ER_ret_rcpt
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006621protein retention in ER lumen
Vocabulary: molecular function
TermDefinition
GO:0046923ER retention sequence binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000133ER lumen protein retaining receptorPRINTSPR00660ERLUMENRcoord: 156..174
score: 71.43
coord: 120..140
score: 73.13
coord: 31..51
score: 68.71
coord: 52..68
score: 62.18
coord: 184..199
score: 61.16
coord: 4..23
score: 67.86
coord: 142..156
score: 69.05
IPR000133ER lumen protein retaining receptorPFAMPF00810ER_lumen_receptcoord: 28..169
e-value: 2.0E-51
score: 174.7
IPR000133ER lumen protein retaining receptorPANTHERPTHR10585ER LUMEN PROTEIN RETAINING RECEPTORcoord: 1..210
IPR000133ER lumen protein retaining receptorPROSITEPS00951ER_LUMEN_RECEPTOR_1coord: 31..48
NoneNo IPR availablePANTHERPTHR10585:SF37ER LUMEN PROTEIN-RETAINING RECEPTOR 2coord: 1..210
NoneNo IPR availableTMHMMTMhelixcoord: 57..79
NoneNo IPR availableTMHMMTMhelixcoord: 178..200
NoneNo IPR availableTMHMMTMhelixcoord: 146..168