Nuclear transport factor 2-like export factor 2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30016103 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Human
Match: NXT2 (nuclear transport factor 2 like export factor 2 [Source:HGNC Symbol;Acc:HGNC:18151]) HSP 1 Score: 82.0333 bits (201), Expect = 8.965e-20 Identity = 45/129 (34.88%), Postives = 68/129 (52.71%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRFLNGS 432 +A AE+ ++ YY TMDK R ++ + TL WNGN V L+ + NFFD+LP S Q+ L QP + + +V + +G V +D +K F+ +L N+ +WKI S FRF + S Sbjct: 13 QACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDG-NKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWS 140
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Human
Match: NXT2 (nuclear transport factor 2 like export factor 2 [Source:HGNC Symbol;Acc:HGNC:18151]) HSP 1 Score: 81.6481 bits (200), Expect = 4.011e-19 Identity = 45/129 (34.88%), Postives = 68/129 (52.71%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRFLNGS 432 +A AE+ ++ YY TMDK R ++ + TL WNGN V L+ + NFFD+LP S Q+ L QP + + +V + +G V +D +K F+ +L N+ +WKI S FRF + S Sbjct: 68 QACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDG-NKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWS 195
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Human
Match: NXT1 (nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913]) HSP 1 Score: 80.1073 bits (196), Expect = 5.718e-19 Identity = 43/125 (34.40%), Postives = 67/125 (53.60%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YYTTMDK R ++ + + TL WNGN V E + FF+ LP S QI + QP + +P +V + I G V ++ +K + F+ +L ++ +WKI S FRF Sbjct: 12 QACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEG-NKQRDFNQNFILTAQASPSNTVWKIASDCFRF 135
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Human
Match: NXT2 (nuclear transport factor 2 like export factor 2 [Source:HGNC Symbol;Acc:HGNC:18151]) HSP 1 Score: 67.0106 bits (162), Expect = 2.929e-14 Identity = 39/113 (34.51%), Postives = 58/113 (51.33%), Query Frame = 1 Query: 103 MDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRFLNGS 432 MDK R ++ + TL WNGN V L+ + NFFD+LP S Q+ L QP + + +V + +G V +D +K F+ +L N+ +WKI S FRF + S Sbjct: 1 MDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDG-NKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWS 112
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Human
Match: NXT2 (nuclear transport factor 2 like export factor 2 [Source:HGNC Symbol;Acc:HGNC:18151]) HSP 1 Score: 67.0106 bits (162), Expect = 2.929e-14 Identity = 39/113 (34.51%), Postives = 58/113 (51.33%), Query Frame = 1 Query: 103 MDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRFLNGS 432 MDK R ++ + TL WNGN V L+ + NFFD+LP S Q+ L QP + + +V + +G V +D +K F+ +L N+ +WKI S FRF + S Sbjct: 1 MDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDG-NKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWS 112
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Celegans
Match: nxt-1 (NTF2-related export protein [Source:UniProtKB/Swiss-Prot;Acc:Q9U757]) HSP 1 Score: 59.6918 bits (143), Expect = 1.063e-11 Identity = 36/126 (28.57%), Postives = 60/126 (47.62%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFK-SVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFLN 426 E ++K +D YY MD+ R I +T WNGN + + I F +LP ++ I SL AQ V+ + + + + G V D SK +L+ ++ DG +K+ S FR+++ Sbjct: 15 ELCNESKKFMDVYYDVMDRKREKIGFLYTQVSNAVWNGNPINGYDSICEFMKALPSTQHDIQSLDAQRLPEGVTGDMSGGMLLNVAGAVTVDGDSKRAFTQTLLLGVE---DGKYKVKSDRFRYVD 137
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Celegans
Match: nxt-1 (NTF2-related export protein [Source:UniProtKB/Swiss-Prot;Acc:Q9U757]) HSP 1 Score: 58.151 bits (139), Expect = 4.006e-11 Identity = 36/125 (28.80%), Postives = 58/125 (46.40%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALEIQNFFDSLPGSRTQILSLSAQPTNPFVSPEFK-SVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFLN 426 E ++K +D YY MD+ R I +T WNGN I F +LP ++ I SL AQ V+ + + + + G V D SK +L+ ++ DG +K+ S FR+++ Sbjct: 15 ELCNESKKFMDVYYDVMDRKREKIGFLYTQVSNAVWNGN-----PINGFMKALPSTQHDIQSLDAQRLPEGVTGDMSGGMLLNVAGAVTVDGDSKRAFTQTLLLGVE---DGKYKVKSDRFRYVD 131
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Fly
Match: Nxt1 (gene:FBgn0028411 transcript:FBtr0072241) HSP 1 Score: 57.3806 bits (137), Expect = 7.869e-11 Identity = 42/133 (31.58%), Postives = 64/133 (48.12%), Query Frame = 1 Query: 40 DSDWSEASEVAEKLIDK----YYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQP-TNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRF 420 DSD E + D YY ++D R I + + TL+WNGN + I+++F LP S Q+ +L AQP + VS + + I +G V + +Q K F IV + ND WK++S +R Sbjct: 2 DSDLKAKVESCARTADTFTRLYYASVDNRRQQIGRLYLDNATLSWNGNGAIGRQMIESYFQELPSSNHQLNTLDAQPIVDQAVSNQLAYL-IMASGSVKFADQQLRK-FQQTFIVTAE-NDK-WKVVSDCYRM 130
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Zebrafish
Match: nxt2 (nuclear transport factor 2-like export factor 2 [Source:ZFIN;Acc:ZDB-GENE-050521-1]) HSP 1 Score: 68.1662 bits (165), Expect = 1.470e-14 Identity = 36/126 (28.57%), Postives = 62/126 (49.21%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMK---DKNDGLWKIISSTFRF 420 ++ +E+ I+ YY MDK R ++ + TL WNGN V E + FF+SLP S Q+ +L QP + + ++ + G V ++ + + L+ + + + +WKI S FRF Sbjct: 13 QSCRYSEEFINIYYECMDKKRRNLKRLYLDKATLVWNGNAVTGQEALGEFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVAAGSVKFEGNKQRFFNQNFLLTAQASPNSDQPVWKIASDCFRF 138
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Zebrafish
Match: nxt2 (nuclear transport factor 2-like export factor 2 [Source:ZFIN;Acc:ZDB-GENE-050521-1]) HSP 1 Score: 68.1662 bits (165), Expect = 1.470e-14 Identity = 36/126 (28.57%), Postives = 62/126 (49.21%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMK---DKNDGLWKIISSTFRF 420 ++ +E+ I+ YY MDK R ++ + TL WNGN V E + FF+SLP S Q+ +L QP + + ++ + G V ++ + + L+ + + + +WKI S FRF Sbjct: 13 QSCRYSEEFINIYYECMDKKRRNLKRLYLDKATLVWNGNAVTGQEALGEFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVAAGSVKFEGNKQRFFNQNFLLTAQASPNSDQPVWKIASDCFRF 138
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Zebrafish
Match: nxt2 (nuclear transport factor 2-like export factor 2 [Source:ZFIN;Acc:ZDB-GENE-050521-1]) HSP 1 Score: 65.855 bits (159), Expect = 7.568e-14 Identity = 36/126 (28.57%), Postives = 63/126 (50.00%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMK----DKNDGLWKIISSTFR 417 ++ +E+ I+ YY MDK R ++ + TL WNGN V E + FF+SLP S Q+ +L QP + + ++ + G V ++ +K + F+ ++ + + +WKI S FR Sbjct: 13 QSCRYSEEFINIYYECMDKKRRNLKRLYLDKATLVWNGNAVTGQEALGEFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVAAGSVKFEG-NKQRFFNQNFLLTAQASPNSDQPVWKIASDCFR 137
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Zebrafish
Match: nxt2 (nuclear transport factor 2-like export factor 2 [Source:ZFIN;Acc:ZDB-GENE-050521-1]) HSP 1 Score: 58.9214 bits (141), Expect = 4.642e-11 Identity = 31/110 (28.18%), Postives = 56/110 (50.91%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKN 381 ++ +E+ I+ YY MDK R ++ + TL WNGN V E + FF+SLP S Q+ +L QP + + ++ + G V ++ +K + F+ ++ K+ Sbjct: 13 QSCRYSEEFINIYYECMDKKRRNLKRLYLDKATLVWNGNAVTGQEALGEFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVAAGSVKFEG-NKQRFFNQNFLLTYGKS 121
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Xenopus
Match: spred2 (sprouty related, EVH1 domain containing 2 [Source:Xenbase;Acc:XB-GENE-485591]) HSP 1 Score: 63.929 bits (154), Expect = 6.957e-13 Identity = 36/128 (28.12%), Postives = 60/128 (46.88%), Query Frame = 1 Query: 43 SDWSEASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDK-NDGLWKIISSTFRF 420 +D A AE+ ++ YY T+DK R + +T + TL WNGN + + + FF+ LP S Q+ P + + K+V + G V ++ + L+ + + +WKI S FRF Sbjct: 8 TDVDLACRAAEEFVNLYYETIDKRRRQLIKLYTDTATLVWNGNPISGQDSLVEFFEMLPSSEFQVNMFDCHPVHEQATQGQKTVLVVAHGIVKFEGNKHHYFNQNFLLSLHATPTNSVWKIASDCFRF 135
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Mouse
Match: Nxt1 (NTF2-related export protein 1 [Source:MGI Symbol;Acc:MGI:1929619]) HSP 1 Score: 79.7221 bits (195), Expect = 5.294e-19 Identity = 41/124 (33.06%), Postives = 64/124 (51.61%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD-VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YYTTMDK R ++ + + TL WNGN V E + FF+ LP S QI + QP + +P +V + I G V ++ + + +L ++ +WKI S FRF Sbjct: 12 QACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDDATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSNTVWKIASDCFRF 135
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Mouse
Match: Nxt1 (NTF2-related export protein 1 [Source:MGI Symbol;Acc:MGI:1929619]) HSP 1 Score: 79.7221 bits (195), Expect = 5.294e-19 Identity = 41/124 (33.06%), Postives = 64/124 (51.61%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD-VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YYTTMDK R ++ + + TL WNGN V E + FF+ LP S QI + QP + +P +V + I G V ++ + + +L ++ +WKI S FRF Sbjct: 12 QACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDDATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSNTVWKIASDCFRF 135
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Mouse
Match: Nxt2 (nuclear transport factor 2-like export factor 2 [Source:MGI Symbol;Acc:MGI:2147914]) HSP 1 Score: 78.9518 bits (193), Expect = 1.101e-18 Identity = 45/125 (36.00%), Postives = 64/125 (51.20%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YY TMDK R ++ + TL WNGN V LE + NFF+ LP S QI L QP + + +V + +G V +D +K F+ +L N +WKI S FRF Sbjct: 13 QACRAAEEFVNIYYETMDKRRHALVRLYLDKATLIWNGNVVTGLEALANFFEMLPSSEFQINMLDCQPVHEQATQCQTTVLVVTSGVVKFDG-NKQHFFNQNFLLTAQSTPNSTVWKIASDCFRF 136
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Mouse
Match: Nxt2 (nuclear transport factor 2-like export factor 2 [Source:MGI Symbol;Acc:MGI:2147914]) HSP 1 Score: 78.9518 bits (193), Expect = 1.101e-18 Identity = 45/125 (36.00%), Postives = 64/125 (51.20%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YY TMDK R ++ + TL WNGN V LE + NFF+ LP S QI L QP + + +V + +G V +D +K F+ +L N +WKI S FRF Sbjct: 13 QACRAAEEFVNIYYETMDKRRHALVRLYLDKATLIWNGNVVTGLEALANFFEMLPSSEFQINMLDCQPVHEQATQCQTTVLVVTSGVVKFDG-NKQHFFNQNFLLTAQSTPNSTVWKIASDCFRF 136
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Mouse
Match: Nxt2 (nuclear transport factor 2-like export factor 2 [Source:MGI Symbol;Acc:MGI:2147914]) HSP 1 Score: 78.1814 bits (191), Expect = 7.684e-18 Identity = 45/125 (36.00%), Postives = 64/125 (51.20%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YY TMDK R ++ + TL WNGN V LE + NFF+ LP S QI L QP + + +V + +G V +D +K F+ +L N +WKI S FRF Sbjct: 69 QACRAAEEFVNIYYETMDKRRHALVRLYLDKATLIWNGNVVTGLEALANFFEMLPSSEFQINMLDCQPVHEQATQCQTTVLVVTSGVVKFDG-NKQHFFNQNFLLTAQSTPNSTVWKIASDCFRF 192
BLAST of Nuclear transport factor 2-like export factor 2 vs. UniProt/SwissProt
Match: sp|A6QNX3|NXT2_BOVIN (NTF2-related export protein 2 OS=Bos taurus OX=9913 GN=NXT2 PE=2 SV=1) HSP 1 Score: 82.8037 bits (203), Expect = 2.014e-19 Identity = 43/124 (34.68%), Postives = 64/124 (51.61%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMK-DKNDGLWKIISSTFRF 420 +A AE+ ++ YY TMDK R ++ + TL WNGN V LE + NFFD LP S Q+ L QP + + +V + +G V +D + + L+ + N+ +WKI S FRF Sbjct: 13 QACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNVVTGLEALANFFDMLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHYFNQNFLLTAQTTANNTVWKIASDCFRF 136
BLAST of Nuclear transport factor 2-like export factor 2 vs. UniProt/SwissProt
Match: sp|Q9NPJ8|NXT2_HUMAN (NTF2-related export protein 2 OS=Homo sapiens OX=9606 GN=NXT2 PE=1 SV=1) HSP 1 Score: 82.0333 bits (201), Expect = 4.305e-19 Identity = 45/129 (34.88%), Postives = 68/129 (52.71%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRFLNGS 432 +A AE+ ++ YY TMDK R ++ + TL WNGN V L+ + NFFD+LP S Q+ L QP + + +V + +G V +D +K F+ +L N+ +WKI S FRF + S Sbjct: 13 QACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDG-NKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWS 140
BLAST of Nuclear transport factor 2-like export factor 2 vs. UniProt/SwissProt
Match: sp|Q9UKK6|NXT1_HUMAN (NTF2-related export protein 1 OS=Homo sapiens OX=9606 GN=NXT1 PE=1 SV=1) HSP 1 Score: 80.1073 bits (196), Expect = 2.746e-18 Identity = 43/125 (34.40%), Postives = 67/125 (53.60%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YYTTMDK R ++ + + TL WNGN V E + FF+ LP S QI + QP + +P +V + I G V ++ +K + F+ +L ++ +WKI S FRF Sbjct: 12 QACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEG-NKQRDFNQNFILTAQASPSNTVWKIASDCFRF 135
BLAST of Nuclear transport factor 2-like export factor 2 vs. UniProt/SwissProt
Match: sp|Q9QZV9|NXT1_MOUSE (NTF2-related export protein 1 OS=Mus musculus OX=10090 GN=Nxt1 PE=1 SV=2) HSP 1 Score: 79.7221 bits (195), Expect = 3.703e-18 Identity = 41/124 (33.06%), Postives = 64/124 (51.61%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD-VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YYTTMDK R ++ + + TL WNGN V E + FF+ LP S QI + QP + +P +V + I G V ++ + + +L ++ +WKI S FRF Sbjct: 12 QACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDDATPSQTTVLVVICGTVKFEGNKQRDFNQNFILTAQASPSNTVWKIASDCFRF 135
BLAST of Nuclear transport factor 2-like export factor 2 vs. UniProt/SwissProt
Match: sp|Q3UNA4|NXT2_MOUSE (NTF2-related export protein 2 OS=Mus musculus OX=10090 GN=Nxt2 PE=2 SV=1) HSP 1 Score: 78.9518 bits (193), Expect = 7.700e-18 Identity = 45/125 (36.00%), Postives = 64/125 (51.20%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRF 420 +A AE+ ++ YY TMDK R ++ + TL WNGN V LE + NFF+ LP S QI L QP + + +V + +G V +D +K F+ +L N +WKI S FRF Sbjct: 13 QACRAAEEFVNIYYETMDKRRHALVRLYLDKATLIWNGNVVTGLEALANFFEMLPSSEFQINMLDCQPVHEQATQCQTTVLVVTSGVVKFDG-NKQHFFNQNFLLTAQSTPNSTVWKIASDCFRF 136
BLAST of Nuclear transport factor 2-like export factor 2 vs. TrEMBL
Match: A0A2Y9EPI5 (NTF2-related export protein 2 OS=Physeter macrocephalus OX=9755 GN=LOC102978168 PE=4 SV=1) HSP 1 Score: 84.3445 bits (207), Expect = 1.549e-17 Identity = 44/124 (35.48%), Postives = 65/124 (52.42%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKD-KNDGLWKIISSTFRF 420 +A + AE+ ++ YY TMDK R +I + TL WNGN V LE + NFFD LP S Q+ L QP + + +V + +G V +D + + L+ + N+ +WKI S FRF Sbjct: 13 QACKAAEEFVNIYYETMDKRRRAITRLYLDKATLVWNGNAVTGLEALANFFDMLPSSEFQVNMLDCQPVHEQATQAQTTVLVVTSGTVKFDGNRQHYFNQNFLLTAQSTANNTVWKIASDCFRF 136
BLAST of Nuclear transport factor 2-like export factor 2 vs. TrEMBL
Match: A0A2Y9S015 (NTF2-related export protein 2-like OS=Physeter macrocephalus OX=9755 GN=LOC102976925 PE=4 SV=1) HSP 1 Score: 83.1889 bits (204), Expect = 3.632e-17 Identity = 44/124 (35.48%), Postives = 64/124 (51.61%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDK-NDGLWKIISSTFRF 420 +A AEK ++ YY TMDK R ++ + TL WNGN+V LE + NFFD LP S Q+ L QP + V +V + +G V +D + + L+ + N+ +WKI S F F Sbjct: 13 QACRAAEKFVNIYYETMDKRRQALTRLYLDKATLIWNGNFVTGLEALTNFFDMLPSSEFQVNMLDCQPVHEQVKQTQTTVLVVTSGTVKFDGNRQHYFKQNFLLTAQSTPNNIVWKIASDCFHF 136
BLAST of Nuclear transport factor 2-like export factor 2 vs. TrEMBL
Match: A0A340XQX0 (NTF2-related export protein 2 OS=Lipotes vexillifer OX=118797 GN=NXT2 PE=4 SV=1) HSP 1 Score: 83.5741 bits (205), Expect = 3.754e-17 Identity = 42/123 (34.15%), Postives = 62/123 (50.41%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRF 420 +A AE+ + YY TMDK R ++ + TL WNGN V LE + FFD+LP S Q+ L QP + + +V + +G V +D + + L+ + D +WKI S FRF Sbjct: 13 QACRAAEEFVSIYYETMDKRRQALTRLYLDKATLVWNGNVVTGLEALTKFFDTLPSSEFQVNMLDCQPVHEQATQSQATVLVVTSGTVKFDGNRQHYFNQNFLLTAQSTPDIVWKIASDCFRF 135
BLAST of Nuclear transport factor 2-like export factor 2 vs. TrEMBL
Match: A0A452DKL9 (Nuclear transport factor 2 like export factor 2 OS=Capra hircus OX=9925 GN=NXT2 PE=4 SV=1) HSP 1 Score: 83.1889 bits (204), Expect = 5.085e-17 Identity = 43/124 (34.68%), Postives = 64/124 (51.61%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMK-DKNDGLWKIISSTFRF 420 +A AE+ ++ YY TMDK R ++ + TL WNGN V LE + NFFD LP S Q+ L QP + + +V + +G V +D + + L+ + N+ +WKI S FRF Sbjct: 13 QACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNVVTGLEALANFFDMLPSSEFQVNMLDCQPVHEQATQAQTTVLVVTSGTVKFDGNKQHYFNQNFLLTAQTTANNTVWKIASDCFRF 136
BLAST of Nuclear transport factor 2-like export factor 2 vs. TrEMBL
Match: H2PWG9 (NXT2 isoform 1 OS=Pongo abelii OX=9601 GN=NXT2 PE=4 SV=1) HSP 1 Score: 82.8037 bits (203), Expect = 5.907e-17 Identity = 46/129 (35.66%), Postives = 68/129 (52.71%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHD--VLIVMKDKNDGLWKIISSTFRFLNGS 432 +A AE+ ++ YY TMDK R ++ + TL WNGN V L+ + NFFD+LP S Q+ L QP + + +V I +G V +D +K F+ +L N+ +WKI S FRF + S Sbjct: 13 QACRAAEEFVNIYYETMDKRRRALTRLYLDQATLIWNGNVVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLIVTSGTVKFDG-NKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWS 140
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Cavefish
Match: nxt2 (nuclear transport factor 2 like export factor 2 [Source:NCBI gene;Acc:103035937]) HSP 1 Score: 65.0846 bits (157), Expect = 1.389e-13 Identity = 34/126 (26.98%), Postives = 61/126 (48.41%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMK---DKNDGLWKIISSTFRF 420 ++ +E+ ++ YY MDK R ++ + TL WNGN + + FF+SLP S Q+ +L QP + + ++ + G V +D + + L+ + + + +WKI S FRF Sbjct: 13 QSCRYSEEFVNIYYDCMDKKRRNLTRLYLDKATLVWNGNAFSGQDSLGEFFESLPSSEFQVHTLDCQPVHEQATQGQTTLLVVTAGLVKFDGNKQRYFNQNFLLTAQPSPNSDQPVWKIASDCFRF 138
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Nematostella
Match: EDO49593 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFE7]) HSP 1 Score: 69.3218 bits (168), Expect = 1.002e-15 Identity = 36/125 (28.80%), Postives = 62/125 (49.60%), Query Frame = 1 Query: 58 ASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQA--LEIQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFLN 426 A+E E + YY T DK R I+ ++ + T+ WNGN V+ ++ FF +LP S + +L QP + P ++ + + G V Y+ + L+ ++ +WK+ S FRFL+ Sbjct: 9 AAEAGETFSNLYYETFDKRRHKISKLYSKNATVVWNGNAVKGGTEQLTEFFTNLPTSEHTLHTLDCQPVSEQAIPGQTTILVIVEGLVQYEGHKAKNFSQNFLLTVEGT---VWKVASDCFRFLD 130
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Medaka
Match: nxt2 (nuclear transport factor 2 like export factor 2 [Source:NCBI gene;Acc:101172743]) HSP 1 Score: 64.6994 bits (156), Expect = 2.215e-13 Identity = 35/126 (27.78%), Postives = 62/126 (49.21%), Query Frame = 1 Query: 55 EASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALE-IQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMK---DKNDGLWKIISSTFRF 420 ++ +E+ ++ YY MDK R ++ + TL WNGN V E + FF+SLP S Q+ +L QP + + ++ + G V ++ + + L+ + + + +WKI S FRF Sbjct: 13 QSCRYSEEFVNIYYDCMDKKRRNLIRLYLDKATLVWNGNAVSGQEALSAFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVTGGIVKFEGNKQRFFNQNFLLTAQATPNNDQPVWKIASDCFRF 138
BLAST of Nuclear transport factor 2-like export factor 2 vs. Planmine SMEST
Match: SMESG000004322.1 (SMESG000004322.1) HSP 1 Score: 273.478 bits (698), Expect = 1.222e-95 Identity = 133/133 (100.00%), Postives = 133/133 (100.00%), Query Frame = 1 Query: 34 MEDSDWSEASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALEIQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFLNGS 432 MEDSDWSEASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALEIQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFLNGS Sbjct: 1 MEDSDWSEASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALEIQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFLNGS 133
BLAST of Nuclear transport factor 2-like export factor 2 vs. Planmine SMEST
Match: SMESG000004332.1 (SMESG000004332.1) HSP 1 Score: 186.808 bits (473), Expect = 2.127e-61 Identity = 89/133 (66.92%), Postives = 110/133 (82.71%), Query Frame = 1 Query: 34 MEDSDWSEASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALEIQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFLNGS 432 M+DS+W+E+SEVAEK+IDKYY+ MD+ R SIN FFTPSGTL+WNG+ V + EIQ F+DSLP S+TQILS+SAQP + VS EFKSV I+I GK+N+ N KSK+FHD LIVMKD D LWKI+SSTFRF++ S Sbjct: 1 MDDSNWTESSEVAEKIIDKYYSNMDQNRISINSFFTPSGTLSWNGHLVNSPEIQIFYDSLPASKTQILSVSAQPISSIVSSEFKSVAIFIVGKINFANYPKSKIFHDNLIVMKDNTDELWKILSSTFRFISES 133
BLAST of Nuclear transport factor 2-like export factor 2 vs. Planmine SMEST
Match: SMESG000047359.1 (SMESG000047359.1) HSP 1 Score: 71.633 bits (174), Expect = 2.616e-16 Identity = 45/130 (34.62%), Postives = 74/130 (56.92%), Query Frame = 1 Query: 34 MEDSDWSEASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQALEIQNFFDSLPGSRTQILSLSAQPTNPFVSPEFKSVQIYITGKVNYDNQSKSKLFHDVLIVMKDKNDGLWKIISSTFRFL 423 ME +W +A+E+ + YY +D R FF+ S +L WNGN + +I+ F+ +P + T+I S SA P N ++ K+V I + G V Y ++ + K+F +VLIV + N+ +I+SS F F+ Sbjct: 1 MEVPNWMKAAEI---IAAHYYRALDNNRKQFFSFFSDSSSLNWNGNCFEGNDIEKFYGRIPKTNTKIYSYSALPINSSITDNEKTVIIKVVGHVKYQDRQR-KVFDEVLIV-EFTNENSIRILSSNFHFI 125 The following BLAST results are available for this feature:
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Nuclear transport factor 2-like export factor 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Nuclear transport factor 2-like export factor 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Nuclear transport factor 2-like export factor 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Nuclear transport factor 2-like export factor 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30016103 ID=SMED30016103|Name=Nuclear transport factor 2-like export factor 2|organism=Schmidtea mediterranea sexual|type=transcript|length=534bpback to top protein sequence of SMED30016103-orf-1 >SMED30016103-orf-1 ID=SMED30016103-orf-1|Name=SMED30016103-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=134bp MEDSDWSEASEVAEKLIDKYYTTMDKTRSSINLFFTPSGTLTWNGNYVQAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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