Protein arginine N-methyltransferase 6

Overview
NameProtein arginine N-methyltransferase 6
Smed IDSMED30016088
Length (bp)1217
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein arginine N-methyltransferase 6 (SMED30016088) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein arginine N-methyltransferase 6 (SMED30016088) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein arginine N-methyltransferase 6 (SMED30016088) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein arginine N-methyltransferase 6 (SMED30016088) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30016088

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30016088h1SMcG0020701 dd_Smed_v4_1336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30016088h1SMcG0020701 dd_Smed_v4_1336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30016088h1SMcG0020701 dd_Smed_v4_1336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30016088h1SMcG0020701 dd_Smed_v4_1336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30016088h1SMcG0020701 dd_Smed_v4_1336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30016088h1SMcG0020701 dd_Smed_v4_1336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Human
Match: PRMT8 (protein arginine methyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:5188])

HSP 1 Score: 192.586 bits (488), Expect = 6.847e-57
Identity = 115/314 (36.62%), Postives = 171/314 (54.46%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAKKVFGIE +S+S+ S K+I  N+L ++I I     E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK GGLMFP RA L+V   E  +  D K    W+ +   Y  D+T     +M++ LVD      + P  +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F         ST+P    THW QT+  L   + + +   I G +   P+    R +   ++L+
Sbjct:   65 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRDVAMKEPLVDI-----VDPKQVVTNACLIKEVDIYTVKTEEL-SFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLD 368          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Human
Match: PRMT8 (protein arginine methyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:5188])

HSP 1 Score: 192.2 bits (487), Expect = 1.190e-56
Identity = 115/314 (36.62%), Postives = 171/314 (54.46%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAKKVFGIE +S+S+ S K+I  N+L ++I I     E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK GGLMFP RA L+V   E  +  D K    W+ +   Y  D+T     +M++ LVD      + P  +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F         ST+P    THW QT+  L   + + +   I G +   P+    R +   ++L+
Sbjct:   74 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRDVAMKEPLVDI-----VDPKQVVTNACLIKEVDIYTVKTEEL-SFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLD 377          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Human
Match: PRMT6 (protein arginine methyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18241])

HSP 1 Score: 190.66 bits (483), Expect = 3.021e-56
Identity = 115/328 (35.06%), Postives = 180/328 (54.88%), Query Frame = 2
Query:  155 DEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEE---TLWQILSRDYDVDLTGSVYTSMQQSLVDNA--VVAELSPHFIVTCKSTALSIDLYSA--QADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS-----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDN 1102
            D+ Y++ Y  +  H  M+ D VRT AY+  I      L+G TV+DVG+GTGILS+FCA+AGA++V+ +EA+++ + +R+++  N L D + ++    E   LP + VDAIVSEWMGY LL E+ML+SVL  R  +LK+GGL+ P  A+LF+A       +D+  E     W  + + Y VD++  +     + L+ ++  VV  LS   ++        ++L  A  + +L   + G F     G+A M     WF  TFP        VLSTSP    THW Q ++ L  P+++ Q + +SG +   PS    R +R+ +  +  D 
Sbjct:   44 DQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPI-----SDQMLEWRLGFWSQVKQHYGVDMS-CLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQ 364          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Human
Match: PRMT1 (protein arginine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5187])

HSP 1 Score: 182.185 bits (461), Expect = 4.785e-53
Identity = 116/353 (32.86%), Postives = 181/353 (51.27%), Query Frame = 2
Query:   68 DSIVTPLTNGIPLKR-----SRIDSDDERKPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++ V  L NG+ L+      S   ++   KP ++D    ++YF SY     H  ML D VRTL Y+ ++   R   +   V+DVGSGTGIL +F A+AGA+KV GIE +S+S+ + K++  N L  V+ I+    E   LPV+ VD I+SEWMGYCL  E+ML +VL  RD +L   GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +VT       +D+Y+ + + +      F ++   N  +  LV +F+  F      +  STSP    THW QT+  +   + +     I G +   P+    R +   I+L+
Sbjct:   12 ENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKDVAIKEPLVD-----VVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLD 354          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Human
Match: PRMT1 (protein arginine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5187])

HSP 1 Score: 179.874 bits (455), Expect = 2.773e-52
Identity = 110/329 (33.43%), Postives = 171/329 (51.98%), Query Frame = 2
Query:  125 SDDERKPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++   KP ++D    ++YF SY     H  ML D VRTL Y+ ++   R   +   V+DVGSGTGIL +F A+AGA+KV GIE +S+S+ + K++  N L  V+ I+    E   LPV+ VD I+SEWMGYCL  E+ML +VL  RD +L   GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +VT       +D+Y+ + + +      F ++   N  +  LV +F+  F      +  STSP    THW QT+  +   + +     I G +   P+    R +   I+L+
Sbjct:   18 AESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKDVAIKEPLVD-----VVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLD 336          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Celegans
Match: prmt-1 (Protein arginine N-methyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U2X0])

HSP 1 Score: 161.384 bits (407), Expect = 8.031e-46
Identity = 105/324 (32.41%), Postives = 173/324 (53.40%), Query Frame = 2
Query:  140 KPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNS-VAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQ-ADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            K  +  ++YF SY     H  ML D VRT  Y+ +I       +   V+DVGSGTGILS+F A+AGAKKVF +E ++++  SRK+I +NNL  ++E++ + V +   LP  ++ VD I+SEWMGYCL  E+ML +VL  RD +L   G++FP +A L+V   E  +   K+++  W      Y  +++     ++++ LVD    A+++     T       +DLY+ +  DL    D  F +    +  +   V +F+  F      +  ST P  + THW QT+  L   + + +   I+G  + +P+ + +R + I I  +
Sbjct:   19 KELTSKDYYFDSYAHFGIHEEMLKDEVRTTTYRNSIYHNSHLFKDKVVMDVGSGTGILSMFAAKAGAKKVFAMEFSNMALTSRKIIADNNLDHIVEVIQAKVEDVHELPGGIEKVDIIISEWMGYCLFYESMLNTVLVARDRWLAPNGMLFPDKARLYVCAIEDRQY--KEDKIHW--WDSVYGFNMSAIKNVAIKEPLVDIVDNAQVN-----TNNCLLKDVDLYTVKIEDLTFKSD--FKLRCTRSDYIQAFVTFFTVEFSKCHKKTGFSTGPDVQYTHWKQTVFYLKDALTVKKGEEITGSFEMAPNKNNERDLDINISFD 331          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Celegans
Match: prmt-1 (Protein arginine N-methyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U2X0])

HSP 1 Score: 161.384 bits (407), Expect = 8.031e-46
Identity = 105/324 (32.41%), Postives = 173/324 (53.40%), Query Frame = 2
Query:  140 KPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNS-VAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQ-ADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            K  +  ++YF SY     H  ML D VRT  Y+ +I       +   V+DVGSGTGILS+F A+AGAKKVF +E ++++  SRK+I +NNL  ++E++ + V +   LP  ++ VD I+SEWMGYCL  E+ML +VL  RD +L   G++FP +A L+V   E  +   K+++  W      Y  +++     ++++ LVD    A+++     T       +DLY+ +  DL    D  F +    +  +   V +F+  F      +  ST P  + THW QT+  L   + + +   I+G  + +P+ + +R + I I  +
Sbjct:   19 KELTSKDYYFDSYAHFGIHEEMLKDEVRTTTYRNSIYHNSHLFKDKVVMDVGSGTGILSMFAAKAGAKKVFAMEFSNMALTSRKIIADNNLDHIVEVIQAKVEDVHELPGGIEKVDIIISEWMGYCLFYESMLNTVLVARDRWLAPNGMLFPDKARLYVCAIEDRQY--KEDKIHW--WDSVYGFNMSAIKNVAIKEPLVDIVDNAQVN-----TNNCLLKDVDLYTVKIEDLTFKSD--FKLRCTRSDYIQAFVTFFTVEFSKCHKKTGFSTGPDVQYTHWKQTVFYLKDALTVKKGEEITGSFEMAPNKNNERDLDINISFD 331          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Celegans
Match: prmt-7 (Protein arginine N-methyltransferase 7 [Source:UniProtKB/Swiss-Prot;Acc:Q9XW42])

HSP 1 Score: 48.1358 bits (113), Expect = 8.605e-6
Identity = 62/262 (23.66%), Postives = 107/262 (40.84%), Query Frame = 2
Query:  281 VIDVGSGTGILSVFCARAGAKKVFGIEA-NSVSELSRKMIDENNLSDVIEIVNSVAERAV----LPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGE----------ENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNA--TMSHLVFWFSTTFPDN--SVLSTSPRDKPT-------HWMQTIVKLP 988
            V+D+G+GTG+LS+  AR GA KV  +E    + + +R +   +  SD I +   ++ER+     +     D IV+E     L+ E  L +     +   K G  + P   ++++   E             N +K EE L +          T +V+  +Q S +      ELS   +      A   D    +  +    D +F  EA+ ++  T+  L+ W+      N  + +   P+ K         HWMQ +  LP
Sbjct:   68 VLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITV---ISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSG-------TAAVF-DVQLSEMKTHEFRELSEPIV------AFKFDFEHEEKII---FDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLP 309          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Fly
Match: Art1 (gene:FBgn0037834 transcript:FBtr0082304)

HSP 1 Score: 182.956 bits (463), Expect = 1.466e-53
Identity = 110/316 (34.81%), Postives = 167/316 (52.85%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQ-ADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSV---LSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIEL 1087
            ++YF SY     H  ML D VRT+ Y+ A+   +   QG TV+DVG GTGILS+F A+AGA +V  ++ +++ E +R+++ +NNL DVI +V    E   LP  ++ VD I+SEWMGYCL  E+ML +VL  RD +LKK G+MFP R  L++   E  +  D+K    W         D+ G   + +++  V   +V  + P  +V+       +DLY+ Q ADL  N    F++    N  +  LV +F+  F         STSP    THW QT+  L   +   +   I+G  +  P+    R +   I++
Sbjct:   54 DYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEK-INWWD--------DVYGFDMSCIRKVAVTEPLVDVVDPKQVVSTSCMVKEVDLYTVQKADL--NFSSKFSLCIKRNDFVQALVTYFNIEFTKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDI 358          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Fly
Match: Art6 (gene:FBgn0038189 transcript:FBtr0082878)

HSP 1 Score: 161.77 bits (408), Expect = 7.141e-46
Identity = 104/335 (31.04%), Postives = 170/335 (50.75%), Query Frame = 2
Query:  155 DEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP----DNSV-LSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDSF 1138
            D  YF+SY  +++H  ML D+VR  A++ AI       Q   V+DVG GTGILS+F A AGA KV  +E   +++++ ++I +N   +V+++V  + E+  LP  ++ VD IVSEWMG  L  E M+ SVL  RD +L +GG + P   +L++ GA      D    T          +D+        Q+ LV+   + +L     +T +    S +L  A+   V      F ++ +    ++ LV +F   FP    + SV L+TSP    THW QT++ L  P+ +  +  + G++  +P+G + R +   + +       RV+   F SF
Sbjct:   16 DSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEAGASKVIAVECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNALYMEAMINSVLFARDKWLTRGGRILPSTGNLWLMGA-----YDPHRRTNLNFWCNVEGIDMGCVRKPFSQEPLVEFVPIQQL-----LTDECFIHSTNLAVARNQPVE-FQSNFQLKVMRTGIINMLVLYFDVLFPSGKSNKSVSLTTSPHSPWTHWEQTVLHLDEPLYVRIRDRVRGVLAMTPTGQDGRGMNFDLHISFRGERTRVES--FKSF 337          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Fly
Match: Art8 (gene:FBgn0032329 transcript:FBtr0080162)

HSP 1 Score: 160.229 bits (404), Expect = 2.334e-45
Identity = 98/280 (35.00%), Postives = 148/280 (52.86%), Query Frame = 2
Query:  164 YFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSV-SELSRKMIDENNLSDVIEIVNSVAERAVLPVKT--VDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP-DNSVLSTSPRDKPTHWMQTIVKLPR 991
            YF  YE+++ H  ML D  R  AY  AI   +   +   V+DVG+GTGILS FCA+AGA+ V+ +EA++V ++++  +I++N L++V++++ S  E  VLP +   VD IVSEWMG+ LL E ML SVL  RD +LK+GGL+FP    +FVA        D      W     + D     +    ++        + +L+P  ++        ++L   +A  + ++     I A           WF   FP ++ VLSTSP   PTHW Q +V LP 
Sbjct:    5 YFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLVYAVEASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLLARDKFLKEGGLLFPSECTIFVAPCSVPSLFDD-----WH----NVDGIKMDTFARKLRTQKSSRPEITQLNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAGNHQGFCIWFDVQFPGEDFVLSTSPLSPPTHWKQCVVVLPE 275          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Fly
Match: Art3 (gene:FBgn0038306 transcript:FBtr0083135)

HSP 1 Score: 157.147 bits (396), Expect = 6.218e-43
Identity = 98/285 (34.39%), Postives = 153/285 (53.68%), Query Frame = 2
Query:  146 CSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTF--PDNSVLSTSPRDKPTHWMQTIVKLPRP 994
            C D+E YFKSY     H+ ML+D VRT  Y+ ++      ++G TV+DVG GTGILS+F ++AGA +V GI+ + +   +  +I +N + +V E++    E   LP    D I+SEWMGY LL E+ML S++  R+N+L   G++ P R  L + G  G++     E   W   S  Y+VD++     S+++ L+   V AE    F++T      + D+ +   +   N    F+++      +S  V +F T F  P   + STSP   PTHW QT+  +  P
Sbjct:  161 CLDNE-YFKSYAHFGIHHEMLSDKVRTSTYRASLLQNEAVVRGKTVLDVGCGTGILSIFASKAGAARVVGIDNSDIVYTAMDIIRKNKVENV-ELIKGRLEDTDLPETKYDIIISEWMGYFLLYESMLDSIIYARENHLNPNGIILPSRCTLSLLGY-GDDTLYADEVEFW---SNVYEVDMSDLRKQSIEEPLM-QVVDAE----FMLTEPEQIANFDIMTVDMNY-PNFTHQFSLKVTKPGRLSAFVGYFETLFELPSPVMFSTSPSATPTHWKQTVFFIENP 433          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Fly
Match: Art3 (gene:FBgn0038306 transcript:FBtr0083134)

HSP 1 Score: 156.762 bits (395), Expect = 1.297e-42
Identity = 98/285 (34.39%), Postives = 153/285 (53.68%), Query Frame = 2
Query:  146 CSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTF--PDNSVLSTSPRDKPTHWMQTIVKLPRP 994
            C D+E YFKSY     H+ ML+D VRT  Y+ ++      ++G TV+DVG GTGILS+F ++AGA +V GI+ + +   +  +I +N + +V E++    E   LP    D I+SEWMGY LL E+ML S++  R+N+L   G++ P R  L + G  G++     E   W   S  Y+VD++     S+++ L+   V AE    F++T      + D+ +   +   N    F+++      +S  V +F T F  P   + STSP   PTHW QT+  +  P
Sbjct:  203 CLDNE-YFKSYAHFGIHHEMLSDKVRTSTYRASLLQNEAVVRGKTVLDVGCGTGILSIFASKAGAARVVGIDNSDIVYTAMDIIRKNKVENV-ELIKGRLEDTDLPETKYDIIISEWMGYFLLYESMLDSIIYARENHLNPNGIILPSRCTLSLLGY-GDDTLYADEVEFW---SNVYEVDMSDLRKQSIEEPLM-QVVDAE----FMLTEPEQIANFDIMTVDMNY-PNFTHQFSLKVTKPGRLSAFVGYFETLFELPSPVMFSTSPSATPTHWKQTVFFIENP 475          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Zebrafish
Match: prmt6 (protein arginine methyltransferase 6 [Source:NCBI gene;Acc:448867])

HSP 1 Score: 197.978 bits (502), Expect = 2.036e-59
Identity = 111/320 (34.69%), Postives = 179/320 (55.94%), Query Frame = 2
Query:  149 SDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAG-----AEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS---VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIE 1084
            ++D  YF SY  +  H  M+ DTVRT  Y+  I      ++G  V+DVG+GTG+LS+FCA+AGA+KV+ +EA+S+++ + K++  N + D IE++ S  E   L  K VD IVSEWMGY LL E+ML SV+  RD +LK GGL+ P RADL++A       EG  +        W  +   Y VD++     + +  +  +  V  ++   +++       +DL +   + +R+++G+F+    G++++     WF+ TFP      VLSTSP    THW Q ++ L   +++ Q + + G +   PS    R I IR++
Sbjct:   21 TEDYMYFDSYSDVTIHEEMIADTVRTNTYRMGIFKNSKSIEGKVVLDVGAGTGVLSLFCAQAGARKVYAVEASSIADQAVKIVKLNQMEDRIEVIKSTLETIELAEK-VDVIVSEWMGYALLHESMLNSVIFARDKWLKPGGLILPSRADLYIAPINDVVVEGRLD-------FWSTVKGQYGVDMSCMTDFARKCIMNKDITVNPVTVEDVLSHPCKFAELDLNTVTLEQLRDVNGSFSCVCFGSSSIHAFCVWFTVTFPAEEKALVLSTSPFKAETHWKQAVLYLDDAVDVMQDTKVEGEISLYPSEENSRHICIRVD 332          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Zebrafish
Match: prmt8b (protein arginine methyltransferase 8b [Source:NCBI gene;Acc:564110])

HSP 1 Score: 191.045 bits (484), Expect = 5.419e-57
Identity = 115/314 (36.62%), Postives = 169/314 (53.82%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAK V+GIE +S+SE S K+I  N+L  VI I+    E   LPV  VD I+SEWMGYCL  E+ML +V+  RD +LK GG MFP RA L+V   E  +  D K    W+ +   Y  D+T     +M + LVD      + P  +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F      +  ST+P    THW QT+  L   + + +   I G +   P+ + +R +    EL+
Sbjct:   14 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHIFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKSNHLDSVITILKGKVEETELPVDQVDIIISEWMGYCLFYESMLNTVIYARDKWLKPGGFMFPDRATLYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRNVAMMEPLVDI-----VDPKQVVTNSCLVKEVDIYTVKTEDL-SFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKTGFSTAPDAPSTHWKQTVFYLEDYLTVRRGEEILGSITVRPNENNERDLDFTFELD 317          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Zebrafish
Match: prmt8b (protein arginine methyltransferase 8b [Source:NCBI gene;Acc:564110])

HSP 1 Score: 190.274 bits (482), Expect = 7.503e-56
Identity = 115/314 (36.62%), Postives = 169/314 (53.82%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAK V+GIE +S+SE S K+I  N+L  VI I+    E   LPV  VD I+SEWMGYCL  E+ML +V+  RD +LK GG MFP RA L+V   E  +  D K    W+ +   Y  D+T     +M + LVD      + P  +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F      +  ST+P    THW QT+  L   + + +   I G +   P+ + +R +    EL+
Sbjct:   99 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHIFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKSNHLDSVITILKGKVEETELPVDQVDIIISEWMGYCLFYESMLNTVIYARDKWLKPGGFMFPDRATLYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRNVAMMEPLVDI-----VDPKQVVTNSCLVKEVDIYTVKTEDL-SFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKTGFSTAPDAPSTHWKQTVFYLEDYLTVRRGEEILGSITVRPNENNERDLDFTFELD 402          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Zebrafish
Match: prmt8b (protein arginine methyltransferase 8b [Source:NCBI gene;Acc:564110])

HSP 1 Score: 190.274 bits (482), Expect = 7.681e-56
Identity = 115/314 (36.62%), Postives = 169/314 (53.82%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAK V+GIE +S+SE S K+I  N+L  VI I+    E   LPV  VD I+SEWMGYCL  E+ML +V+  RD +LK GG MFP RA L+V   E  +  D K    W+ +   Y  D+T     +M + LVD      + P  +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F      +  ST+P    THW QT+  L   + + +   I G +   P+ + +R +    EL+
Sbjct:  100 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHIFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKSNHLDSVITILKGKVEETELPVDQVDIIISEWMGYCLFYESMLNTVIYARDKWLKPGGFMFPDRATLYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRNVAMMEPLVDI-----VDPKQVVTNSCLVKEVDIYTVKTEDL-SFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKTGFSTAPDAPSTHWKQTVFYLEDYLTVRRGEEILGSITVRPNENNERDLDFTFELD 403          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Zebrafish
Match: PRMT8 (protein arginine N-methyltransferase 8-B-like [Source:NCBI gene;Acc:556054])

HSP 1 Score: 186.037 bits (471), Expect = 2.586e-54
Identity = 114/314 (36.31%), Postives = 167/314 (53.18%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAK V+GIE +S+SE S K+I  N+L  VI I     E   LPV  VD I+SEWMGYCL  E+ML +V+  RD +LK GGLMFP RA L+V   E  +  D K    W+ +   Y  D+T     +M++ LVD     +     +V+       +D+Y+ + + + +   +F ++   N  +  LV +F+  F      +  ST+P    THW QT+  L   + + +   I G V   P+    R +    EL+
Sbjct:   90 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHIFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKANHLDSVITIFKGKVEETELPVDQVDIIISEWMGYCLFYESMLNTVIYARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRNVAMKEPLVDIVDSKQ-----VVSNSCLIKEVDIYTVKPEEL-SFTSSFCLQIQRNDYIHALVTYFNIEFTKCHKKTGFSTAPDAPFTHWKQTVFYLEEYLTVKRGEEIVGTVSMKPNEKNVRDLDFTFELD 393          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Xenopus
Match: prmt6 (protein arginine methyltransferase 6 [Source:NCBI gene;Acc:100145123])

HSP 1 Score: 210.69 bits (535), Expect = 2.207e-64
Identity = 129/331 (38.97%), Postives = 189/331 (57.10%), Query Frame = 2
Query:  164 YFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEG---EENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAE--LSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP-DNSV-LSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDS 1135
            YF+ Y  +  H  M+ DTVRT AYK A+    + LQG TV+DVG+GTGILSVF  +AGA+ V+ +EA+S+S+L+ +++  N++ + ++++NS  E A +P + VDAIVSEWMGY L+ E+ML SV+  RD +LK GGL+ P  ADLF+A       E   D      W  +   Y VD+  S   S  +S + N  +A   +SP  +++      S+DL     + V NL G+F     G++ +     WFS TFP +NSV LSTSP  + THW QT++ L   +++ Q + I+G V  SPS    R +R+ +         R  Q    S
Sbjct:   18 YFQCYSDVSVHEEMIADTVRTNAYKLALLRNHSSLQGKTVLDVGAGTGILSVFSVQAGAQAVYAVEASSMSQLACQVVKSNDMENKVKVLNSSVESAEIP-EQVDAIVSEWMGYALMYESMLPSVIYARDKWLKPGGLILPSCADLFIAPVNDLIVESRLD-----FWSEVKGMYGVDM--SCMQSFARSCIMNKEMAVNLVSPEDVLSFPVRFASLDLNVCTQEEVCNLHGSFQFSCFGSSLLHGFAVWFSVTFPGENSVTLSTSPYGEETHWKQTLLYLDEEVQVEQDTEITGDVTLSPSDINPRHLRVLLNYSIGGGLRRTKQFQMGS 340          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Xenopus
Match: PRMT8 (protein arginine methyltransferase 8 [Source:NCBI gene;Acc:100491340])

HSP 1 Score: 188.734 bits (478), Expect = 2.759e-55
Identity = 116/342 (33.92%), Postives = 181/342 (52.92%), Query Frame = 2
Query:   74 IVTPLTNGIPLKRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            I TP+    P  R ++      +  +  ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGA+KV+GIE +SVS+ S K+I  N+L ++I I     E   LPV  VD I++EWMGYCL  E+ML +V+  RD +LK GGLMFP RA L++   E  +  D K    W+ +   Y  D+T     ++++ LVD      + P  +VT       ID+Y+ + + +     AF ++   N  +  LV +F+  F      +  ST+P    THW QT+  L   + + +   + G +   P+ +  R +   ++L+
Sbjct:   49 IHTPIQPSCP-GRGKMAKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGARKVYGIECSSVSDYSEKIIKANHLDNIITIFRGKVEEVELPVDKVDIIITEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYIVAIEDRQYKDFKIH-WWENV---YGFDMTCIRDVAIKEPLVDI-----VDPKQVVTNSCLIKEIDIYTVKTEELA-FTAAFCLQVQRNDYVHALVTYFNIEFTKCHKKTGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEELFGTISMKPNANNIRDLDFTVDLD 379          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Xenopus
Match: il1rap (interleukin 1 receptor accessory protein [Source:Xenbase;Acc:XB-GENE-492428])

HSP 1 Score: 185.267 bits (469), Expect = 2.728e-54
Identity = 116/355 (32.68%), Postives = 181/355 (50.99%), Query Frame = 2
Query:   62 NADSIVTPLTNGIPLKR-----SRIDSDDERKPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            N ++ V  L NG+ L+      S    +   KP ++D    ++YF SY     H  ML D VRTL Y+ ++   R   +   V+DVGSGTGIL +F A+AGAKKV GIE +S+S+ + K++  N L  V+ I+    E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +L   GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +VT       +D+Y+ + D +      F ++   N  +  LV +F+  F      +  STSP    THW QT+  +   + +     I G +   P+    R +   ++++
Sbjct:    8 NMENFVAKLANGMSLRTPIEDVSCTQPESSVKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAIKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIYARDKWLTPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKDVAIKEPLVD-----VVDPKQLVTNACLIKEVDIYTVKVDDL-TFTSPFCLQVKRNDYIHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTISMKPNAKNNRDLDFTVDID 352          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Xenopus
Match: il1rap (interleukin 1 receptor accessory protein [Source:Xenbase;Acc:XB-GENE-492428])

HSP 1 Score: 182.57 bits (462), Expect = 2.172e-53
Identity = 115/352 (32.67%), Postives = 179/352 (50.85%), Query Frame = 2
Query:   71 SIVTPLTNGIPLKR-----SRIDSDDERKPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            + V  L NG+ L+      S    +   KP ++D    ++YF SY     H  ML D VRTL Y+ ++   R   +   V+DVGSGTGIL +F A+AGAKKV GIE +S+S+ + K++  N L  V+ I+    E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +L   GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +VT       +D+Y+ + D +      F ++   N  +  LV +F+  F      +  STSP    THW QT+  +   + +     I G +   P+    R +   ++++
Sbjct:    1 NFVAKLANGMSLRTPIEDVSCTQPESSVKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAIKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIYARDKWLTPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKDVAIKEPLVD-----VVDPKQLVTNACLIKEVDIYTVKVDDL-TFTSPFCLQVKRNDYIHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTISMKPNAKNNRDLDFTVDID 342          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Xenopus
Match: il1rap (interleukin 1 receptor accessory protein [Source:Xenbase;Acc:XB-GENE-492428])

HSP 1 Score: 181.415 bits (459), Expect = 4.502e-53
Identity = 112/336 (33.33%), Postives = 173/336 (51.49%), Query Frame = 2
Query:  104 LKRSRIDSDDERKPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            LK S    +   KP ++D    ++YF SY     H  ML D VRTL Y+ ++   R   +   V+DVGSGTGIL +F A+AGAKKV GIE +S+S+ + K++  N L  V+ I+    E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +L   GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +VT       +D+Y+ + D +      F ++   N  +  LV +F+  F      +  STSP    THW QT+  +   + +     I G +   P+    R +   ++++
Sbjct:    7 LKVSCTQPESSVKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAIKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIYARDKWLTPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKDVAIKEPLVD-----VVDPKQLVTNACLIKEVDIYTVKVDDL-TFTSPFCLQVKRNDYIHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTISMKPNAKNNRDLDFTVDID 332          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Mouse
Match: Prmt8 (protein arginine N-methyltransferase 8 [Source:MGI Symbol;Acc:MGI:3043083])

HSP 1 Score: 192.971 bits (489), Expect = 5.701e-57
Identity = 116/314 (36.94%), Postives = 171/314 (54.46%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAKKVFGIE +S+S+ S K+I  N+L +VI I     E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK GGLMFP RA L+V   E  +  D K    W+ +   Y  D+T     +M++ LVD      + P  +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F         ST+P    THW QT+  L   + + +   I G +   P+    R +   ++L+
Sbjct:   74 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRDVAMKEPLVDI-----VDPKQVVTNACLIKEVDIYTVKTEEL-SFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLD 377          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Mouse
Match: Prmt6 (protein arginine N-methyltransferase 6 [Source:MGI Symbol;Acc:MGI:2139971])

HSP 1 Score: 191.815 bits (486), Expect = 8.095e-57
Identity = 118/334 (35.33%), Postives = 183/334 (54.79%), Query Frame = 2
Query:  137 RKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEE---TLWQILSRDYDVDLTGSVYTSMQQSLVDNA--VVAELSPHFIVTCKSTALSIDLYSA--QADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS-----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDN 1102
            R     D+ Y++ Y  +  H  M+ D VRT AY+  I      L+G TV+DVG+GTGILS+FCA+AGA++V+ +EA+++ + +R+++  N L D + ++    E   LP + VDAIVSEWMGY LL E+ML+SVL  R  +LK+GGL+ P  A+LFVA       +D+  E     W  + + Y VD++  + +   + L+ ++  VV +LS   ++        ++L  A  + +L   + G F     G+A +     WF  TFP        VLSTSP    THW Q ++ L  P+ + Q + ISG +   PS    R +RI +  +  D+
Sbjct:   41 RTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELP-ERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPI-----SDQMLEWRLGFWSQVKQHYGVDMS-CMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPFHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILLRYKVGDH 367          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Mouse
Match: Prmt6 (protein arginine N-methyltransferase 6 [Source:MGI Symbol;Acc:MGI:2139971])

HSP 1 Score: 191.815 bits (486), Expect = 8.095e-57
Identity = 118/334 (35.33%), Postives = 183/334 (54.79%), Query Frame = 2
Query:  137 RKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEE---TLWQILSRDYDVDLTGSVYTSMQQSLVDNA--VVAELSPHFIVTCKSTALSIDLYSA--QADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS-----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDN 1102
            R     D+ Y++ Y  +  H  M+ D VRT AY+  I      L+G TV+DVG+GTGILS+FCA+AGA++V+ +EA+++ + +R+++  N L D + ++    E   LP + VDAIVSEWMGY LL E+ML+SVL  R  +LK+GGL+ P  A+LFVA       +D+  E     W  + + Y VD++  + +   + L+ ++  VV +LS   ++        ++L  A  + +L   + G F     G+A +     WF  TFP        VLSTSP    THW Q ++ L  P+ + Q + ISG +   PS    R +RI +  +  D+
Sbjct:   41 RTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELP-ERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPI-----SDQMLEWRLGFWSQVKQHYGVDMS-CMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPFHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILLRYKVGDH 367          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Mouse
Match: Prmt6 (protein arginine N-methyltransferase 6 [Source:MGI Symbol;Acc:MGI:2139971])

HSP 1 Score: 191.815 bits (486), Expect = 8.095e-57
Identity = 118/334 (35.33%), Postives = 183/334 (54.79%), Query Frame = 2
Query:  137 RKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEE---TLWQILSRDYDVDLTGSVYTSMQQSLVDNA--VVAELSPHFIVTCKSTALSIDLYSA--QADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS-----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDN 1102
            R     D+ Y++ Y  +  H  M+ D VRT AY+  I      L+G TV+DVG+GTGILS+FCA+AGA++V+ +EA+++ + +R+++  N L D + ++    E   LP + VDAIVSEWMGY LL E+ML+SVL  R  +LK+GGL+ P  A+LFVA       +D+  E     W  + + Y VD++  + +   + L+ ++  VV +LS   ++        ++L  A  + +L   + G F     G+A +     WF  TFP        VLSTSP    THW Q ++ L  P+ + Q + ISG +   PS    R +RI +  +  D+
Sbjct:   41 RTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELP-ERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPI-----SDQMLEWRLGFWSQVKQHYGVDMS-CMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPFHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILLRYKVGDH 367          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Mouse
Match: Prmt1 (protein arginine N-methyltransferase 1 [Source:MGI Symbol;Acc:MGI:107846])

HSP 1 Score: 182.57 bits (462), Expect = 2.444e-53
Identity = 116/353 (32.86%), Postives = 181/353 (51.27%), Query Frame = 2
Query:   68 DSIVTPLTNGIPLKR-----SRIDSDDERKPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++ V  L NG+ L+      S   ++   KP ++D    ++YF SY     H  ML D VRTL Y+ ++   R   +   V+DVGSGTGIL +F A+AGA+KV GIE +S+S+ + K++  N L  V+ I+    E   LPV+ VD I+SEWMGYCL  E+ML +VL  RD +L   GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +VT       +D+Y+ + + +      F ++   N  +  LV +F+  F      +  STSP    THW QT+  +   + +     I G +   P+    R +   I+L+
Sbjct:   12 ENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKDVAIKEPLVD-----VVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLD 354          
BLAST of Protein arginine N-methyltransferase 6 vs. UniProt/SwissProt
Match: sp|B0JYW5|ANM6_XENTR (Protein arginine N-methyltransferase 6 OS=Xenopus tropicalis OX=8364 GN=prmt6 PE=2 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 6.937e-65
Identity = 130/331 (39.27%), Postives = 190/331 (57.40%), Query Frame = 2
Query:  164 YFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEG---EENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAE--LSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP-DNSV-LSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDS 1135
            YF+ Y  +  H  M+ DTVRT AYK A+    + LQG TV+DVG+GTGILSVF  +AGA+ V+ +EA+S+S+L+ +++  N++ + ++++NS  E A +P + VDAIVSEWMGY L+ E+ML SV+  RD +LK GGL+ P  ADLF+A       E   D      W  +   Y VD+  S   S  +S + N  +A   +SP  +++      S+DL     + VRNL G+F     G++ +     WFS TFP +NSV LSTSP  + THW QT++ L   +++ Q + I+G V  SPS    R +R+ +         R  Q    S
Sbjct:   18 YFQCYSDVSVHEEMIADTVRTNAYKLALLRNHSSLQGKTVLDVGAGTGILSVFSVQAGAQAVYAVEASSMSQLACQVVKSNDMENKVKVLNSSVESAEIP-EQVDAIVSEWMGYALMYESMLPSVIYARDKWLKPGGLILPSCADLFIAPVNDLIVESRLD-----FWSEVKGMYGVDM--SCMQSFARSCIMNKEMAVNLVSPEDVLSFPVRFASLDLNVCTQEEVRNLHGSFQFSCFGSSLLHGFAVWFSVTFPGENSVTLSTSPYGEETHWKQTLLYLDEEVQVEQDTEITGDVTLSPSDINPRHLRVLLNYSIGGGLRRTKQFQMGS 340          
BLAST of Protein arginine N-methyltransferase 6 vs. UniProt/SwissProt
Match: sp|Q68EZ3|ANM6_XENLA (Protein arginine N-methyltransferase 6 OS=Xenopus laevis OX=8355 GN=prmt6 PE=2 SV=1)

HSP 1 Score: 213.001 bits (541), Expect = 1.705e-64
Identity = 124/331 (37.46%), Postives = 183/331 (55.29%), Query Frame = 2
Query:  155 DEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAE--LSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS--VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDS 1135
            D+ YF+ Y  +  H  M+ DTVRT  YK+AI      LQG TV+DVG+GTGILSVFC +AGA +V+ +EA++VS+L+  ++  N + + ++++NS  E A +P + VDAIVSEWMGY L+ E+ML SV+  RD +LK GG++ P  ADLF+A     +   +     W  +   Y VD+  S       S + N  +A   LSP  +++      S+DL     + VRNL G+F     G++ +     WF+ TFP      LSTSP  + THW QT++ L   I++ Q + I+G +  SPS    R +R  +         R    H  +
Sbjct:   15 DQEYFQCYSDVSIHEEMIADTVRTNGYKQAILHNHCALQGLTVLDVGAGTGILSVFCVQAGATRVYAVEASAVSQLASHVVTLNGMDNKVKVLNSPVESAEIP-EQVDAIVSEWMGYALMYESMLPSVIYARDKWLKPGGIILPSAADLFIAPI--NDRVVESRLDFWNEVKGLYGVDM--SCMRPFAHSCIMNKEMAVNLLSPEDVLSFPVRFASLDLNVCTQEEVRNLHGSFQFSCFGSSLLHGFALWFTVTFPGEKTVTLSTSPYGEETHWKQTLLYLDEEIQVEQDTDITGDITLSPSDVNPRHLRALLNYSIGGGLRRTKHFHMGT 340          
BLAST of Protein arginine N-methyltransferase 6 vs. UniProt/SwissProt
Match: sp|Q6NWG4|ANM6_DANRE (Protein arginine N-methyltransferase 6 OS=Danio rerio OX=7955 GN=prmt6 PE=2 SV=2)

HSP 1 Score: 197.978 bits (502), Expect = 1.379e-58
Identity = 111/320 (34.69%), Postives = 179/320 (55.94%), Query Frame = 2
Query:  149 SDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAG-----AEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS---VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIE 1084
            ++D  YF SY  +  H  M+ DTVRT  Y+  I      ++G  V+DVG+GTG+LS+FCA+AGA+KV+ +EA+S+++ + K++  N + D IE++ S  E   L  K VD IVSEWMGY LL E+ML SV+  RD +LK GGL+ P RADL++A       EG  +        W  +   Y VD++     + +  +  +  V  ++   +++       +DL +   + +R+++G+F+    G++++     WF+ TFP      VLSTSP    THW Q ++ L   +++ Q + + G +   PS    R I IR++
Sbjct:   15 TEDYMYFDSYSDVTIHEEMIADTVRTNTYRMGIFKNSKSIEGKVVLDVGAGTGVLSLFCAQAGARKVYAVEASSIADQAVKIVKLNQMEDRIEVIKSTLETIELAEK-VDVIVSEWMGYALLHESMLNSVIFARDKWLKPGGLILPSRADLYIAPINDVVVEGRLD-------FWSTVKGQYGVDMSCMTDFARKCIMNKDITVNPVTVEDVLSHPCKFAELDLNTVTLEQLRDVNGSFSCVCFGSSSIHAFCVWFTVTFPAEEKALVLSTSPFKAETHWKQAVLYLDDAVDVMQDTKVEGEISLYPSEENSRHICIRVD 326          
BLAST of Protein arginine N-methyltransferase 6 vs. UniProt/SwissProt
Match: sp|Q6PAK3|ANM8_MOUSE (Protein arginine N-methyltransferase 8 OS=Mus musculus OX=10090 GN=Prmt8 PE=1 SV=2)

HSP 1 Score: 192.971 bits (489), Expect = 3.988e-56
Identity = 116/314 (36.94%), Postives = 171/314 (54.46%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAKKVFGIE +S+S+ S K+I  N+L +VI I     E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK GGLMFP RA L+V   E  +  D K    W+ +   Y  D+T     +M++ LVD      + P  +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F         ST+P    THW QT+  L   + + +   I G +   P+    R +   ++L+
Sbjct:   74 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRDVAMKEPLVDI-----VDPKQVVTNACLIKEVDIYTVKTEEL-SFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLD 377          
BLAST of Protein arginine N-methyltransferase 6 vs. UniProt/SwissProt
Match: sp|Q6NZB1|ANM6_MOUSE (Protein arginine N-methyltransferase 6 OS=Mus musculus OX=10090 GN=Prmt6 PE=1 SV=2)

HSP 1 Score: 191.815 bits (486), Expect = 5.662e-56
Identity = 118/334 (35.33%), Postives = 183/334 (54.79%), Query Frame = 2
Query:  137 RKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEE---TLWQILSRDYDVDLTGSVYTSMQQSLVDNA--VVAELSPHFIVTCKSTALSIDLYSA--QADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS-----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDN 1102
            R     D+ Y++ Y  +  H  M+ D VRT AY+  I      L+G TV+DVG+GTGILS+FCA+AGA++V+ +EA+++ + +R+++  N L D + ++    E   LP + VDAIVSEWMGY LL E+ML+SVL  R  +LK+GGL+ P  A+LFVA       +D+  E     W  + + Y VD++  + +   + L+ ++  VV +LS   ++        ++L  A  + +L   + G F     G+A +     WF  TFP        VLSTSP    THW Q ++ L  P+ + Q + ISG +   PS    R +RI +  +  D+
Sbjct:   41 RTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELP-ERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPI-----SDQMLEWRLGFWSQVKQHYGVDMS-CMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGVGGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPFHPATHWKQALLYLNEPVPVEQDTDISGEITLLPSPDNPRRLRILLRYKVGDH 367          
BLAST of Protein arginine N-methyltransferase 6 vs. TrEMBL
Match: A0A2R5LAC5 (Protein arginine n-methyltransferase prmt1 (Fragment) OS=Ornithodoros turicata OX=34597 PE=3 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 8.746e-64
Identity = 121/332 (36.45%), Postives = 197/332 (59.34%), Query Frame = 2
Query:  104 LKRSRIDSDDERKPCS-----DDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAG-AEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRI 1081
            LKR R D++++R+         D  YF+ Y  +D H  M+ D+ RT AY++ I      L   TV+DVG+GTGILS+FCA+AGAK+V+ IEA+ V++++RK++  N +   +E++ S  E A LP K VD IVSEWMGY LL E+ML SV+  RD +LKK G++ P +A +F+A   + +E  ++ E   W+++  ++ VD++  V    +  L  +  V  +    +++  +  L +DLY+ + + + +++  F     G+  +   V WFS  FP + +LSTSP D  THW QT++ +  P+++ Q SII G +  +PS    R + I +
Sbjct:    7 LKRKREDTEEKRQEVQKIRTKHDNEYFRCYAGLDIHREMIGDSSRTFAYRKGILNNYARLYQKTVLDVGAGTGILSMFCAQAGAKRVYAIEASDVAQVARKVVSSNGVEQQVEVIQSRVEDADLPDK-VDVIVSEWMGYMLLYESMLQSVIYARDKWLKKDGVLLPEKARMFIAPLTDPDEGLERVE--FWKMVKDNFHVDMS-CVVEFAKAELYKHITVKAVDVENVISRGTCFLELDLYTVKPEDLHSVEEEFVCCCYGHGKVHAFVIWFSVEFPQDVILSTSPYDSETHWQQTVLYI-NPVDVKQDSIIRGTITINPSAEHHRMLDIHL 333          
BLAST of Protein arginine N-methyltransferase 6 vs. TrEMBL
Match: A0A3B4CE10 (Protein arginine methyltransferase 6 OS=Pygocentrus nattereri OX=42514 PE=3 SV=1)

HSP 1 Score: 217.624 bits (553), Expect = 4.314e-63
Identity = 129/345 (37.39%), Postives = 194/345 (56.23%), Query Frame = 2
Query:  107 KRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETL--WQILSRDYDVDLTGSVYTSMQQSLVDNA--VVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS-----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIEL---EHSDNS 1105
            K+ ++DS       + D  YF+SY  +  H  ML DTVRT  Y+R I     ++QG  V+DVG+GTG+LSVFCA+AGA+KV+ +EA+S++E + +++  N L+D +E++    E A LP K VD IVSEWMGY LL E+ML SV+  RD +L+ GGL+ P RA+LFVA      N    EE L  W ++   Y VD+  S  T   +S + N    V  +S   +++       +DL++   + ++ + G+F     G+++++    WF+ TFP        VLSTSP    THW Q ++ L  P+++ Q + + G +   PS    R I I +E    EH   S
Sbjct:   59 KKRKLDSS------AQDSLYFESYADVTIHEEMLADTVRTDTYRRGIFRAGEQIQGKAVLDVGAGTGVLSVFCAQAGARKVYAVEASSIAEQAARVVRLNGLADRVEVIRGTVESAELPEK-VDVIVSEWMGYALLHESMLNSVIFARDRWLRPGGLILPERAELFVAPI----NHLVAEERLSFWSMVKGQYGVDM--SCMTDFARSCIMNGEISVQPVSVEDVLSHPCRFGMLDLHTVTPEQLKRVSGSFCCRCFGSSSLNAFCVWFAVTFPGEDGTQPLVLSTSPFKPETHWKQAVLYLDEPVDVVQDTRVEGSISMFPSEQSSRHICIHVEYTIGEHKQKS 390          
BLAST of Protein arginine N-methyltransferase 6 vs. TrEMBL
Match: A0A0C9S2P8 (Protein arginine n-methyltransferase prmt1 (Fragment) OS=Amblyomma americanum OX=6943 PE=2 SV=1)

HSP 1 Score: 214.157 bits (544), Expect = 3.240e-62
Identity = 122/336 (36.31%), Postives = 193/336 (57.44%), Query Frame = 2
Query:  104 LKRSRIDSDDERKPCS------DDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGA----EGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRI 1081
            +KR R D  +E+   S       D  YFK Y  +D H  M+ D  RT  Y++AI    + L    V+D+G+GTGILS+FCA+AGAK V+ +EA+ V+E+++K++  N + D + ++ S  E AVLP K VDAIVSEWMGY LL E+ML SV+S RD +LKK G++ P +A +F+A      EG E  D      W+++  ++ VD++  V    +  L  +  V  +    +++  +  L +DLY+ +++ ++ +   F     G+  +   V WFS  FP + +LSTSP D  THW QT++ +  P+++ Q S I G +  +PS    R + + +
Sbjct:   12 IKRRRSDDSEEKSEESLKLRTRHDNEYFKCYAGLDIHREMIGDYARTFTYRKAILNNYSNLYQKAVLDLGAGTGILSMFCAQAGAKTVYAVEASDVAEVAKKVVSSNKVDDQVIVIQSKVEDAVLPEK-VDAIVSEWMGYMLLYESMLQSVISARDKWLKKDGILLPEKARMFIAPLTDPDEGLERID-----FWKMVKENFHVDMS-CVTEFAKAELYKHITVKTVDAENVISRDTCFLELDLYTVKSEDLQCIKENFMCCCYGHGRVHAFVIWFSVEFPLDVILSTSPYDSETHWQQTVLFI-NPVDVKQDSEIRGTITINPSADHHRMLDVEL 339          
BLAST of Protein arginine N-methyltransferase 6 vs. TrEMBL
Match: A0A060Y6B7 (Uncharacterized protein OS=Oncorhynchus mykiss OX=8022 GN=GSONMT00004664001 PE=3 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 3.329e-62
Identity = 115/314 (36.62%), Postives = 182/314 (57.96%), Query Frame = 2
Query:  155 DEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIE 1084
            D  YF SY  +  H  M+ DTVRT  Y+  I    + +QG  V+DVG+GTG+LS+FCA+AGA+KV+ +EA+S+++ + K++  N + D+I+++    E   LP + VD IVSEWMGY LL E+ML SVL  RD +LK GGL+ P +A+L++A        D+   + W  +   YDVD++     + +  + ++  V  ++   +++  S    +DLYS   + ++++ GAF  E  G++ ++ L  WF+ TFP       VLSTSP    THW Q ++ L   + + Q + + G V  SPS    R I I ++
Sbjct:   16 DNLYFDSYSDVTIHEEMIADTVRTNTYRTGILRNSSLIQGKVVLDVGAGTGVLSIFCAQAGARKVYAVEASSIADQAVKIVKHNKMEDIIDVIKGTLETIDLP-EQVDVIVSEWMGYALLHESMLNSVLFARDKWLKAGGLILPSKAELYIAPINDFVVEDRL--SFWSTVKDQYDVDMSCMSDFARKCIMSNDITVNLVTVEDVLSHPSKFAELDLYSVTTEQLKSVKGAFKCECFGSSAVNALCVWFTVTFPGGEEKPLVLSTSPFKPETHWKQAVLYLDEAVNVRQDTTVVGEVNMSPSEDSSRHICIHVD 326          
BLAST of Protein arginine N-methyltransferase 6 vs. TrEMBL
Match: W5LU86 (Protein arginine methyltransferase 6 OS=Astyanax mexicanus OX=7994 PE=3 SV=2)

HSP 1 Score: 214.157 bits (544), Expect = 3.446e-62
Identity = 121/342 (35.38%), Postives = 192/342 (56.14%), Query Frame = 2
Query:  107 KRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVA--ELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIEL---EHSDNS 1105
            K+ R D++      + D  YF+SY  +  H  ML DTVRT  Y+RAI      L G  V+DVG+GTG+LSVFCA+AGA++V+ +EA+S++E + +++ +N + D ++++    E   LP + VD IVSEWMGY LL E+ML SV++ RD +LK GGL+ P RA+LFVA     +   ++    W  +   Y VD+  S      +S V N  +A   ++   +++       +DL +   + ++ + GAF  +  G+++++ L  WF+ TFP       VLSTSP    THW Q ++ L  P+++ Q + + G +   PS    R + I ++    EH   S
Sbjct:   14 KKRRQDNNSSGGGSAQDSLYFQSYADVSIHEEMLADTVRTDTYRRAIFRCAAALAGKAVLDVGAGTGVLSVFCAQAGARRVYAVEASSIAEQAARIVRQNRVEDRVQVIRGTVESVELP-ERVDVIVSEWMGYALLHESMLNSVITARDRWLKPGGLILPERAELFVAPI--SDLVAEERLNFWDTVKGQYGVDM--SCMAEFARSCVLNGEIAVHPVTVEDVLSHPCRFAQLDLRTVTLEELKRVSGAFCCQCFGSSSLNALCVWFTVTFPAEDMPPLVLSTSPFKAETHWKQAVLYLDEPVDVRQDTKVEGNISMYPSEKSSRYVCIHVDYTVGEHKQKS 350          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Cavefish
Match: prmt6 (protein arginine methyltransferase 6 [Source:NCBI gene;Acc:448867])

HSP 1 Score: 214.157 bits (544), Expect = 1.305e-65
Identity = 121/342 (35.38%), Postives = 192/342 (56.14%), Query Frame = 2
Query:  107 KRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVA--ELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIEL---EHSDNS 1105
            K+ R D++      + D  YF+SY  +  H  ML DTVRT  Y+RAI      L G  V+DVG+GTG+LSVFCA+AGA++V+ +EA+S++E + +++ +N + D ++++    E   LP + VD IVSEWMGY LL E+ML SV++ RD +LK GGL+ P RA+LFVA     +   ++    W  +   Y VD+  S      +S V N  +A   ++   +++       +DL +   + ++ + GAF  +  G+++++ L  WF+ TFP       VLSTSP    THW Q ++ L  P+++ Q + + G +   PS    R + I ++    EH   S
Sbjct:   14 KKRRQDNNSSGGGSAQDSLYFQSYADVSIHEEMLADTVRTDTYRRAIFRCAAALAGKAVLDVGAGTGVLSVFCAQAGARRVYAVEASSIAEQAARIVRQNRVEDRVQVIRGTVESVELP-ERVDVIVSEWMGYALLHESMLNSVITARDRWLKPGGLILPERAELFVAPI--SDLVAEERLNFWDTVKGQYGVDM--SCMAEFARSCVLNGEIAVHPVTVEDVLSHPCRFAQLDLRTVTLEELKRVSGAFCCQCFGSSSLNALCVWFTVTFPAEDMPPLVLSTSPFKAETHWKQAVLYLDEPVDVRQDTKVEGNISMYPSEKSSRYVCIHVDYTVGEHKQKS 350          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Cavefish
Match: prmt8b (protein arginine N-methyltransferase 8-B [Source:NCBI gene;Acc:103024775])

HSP 1 Score: 191.815 bits (486), Expect = 1.710e-56
Identity = 119/315 (37.78%), Postives = 168/315 (53.33%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQ-ADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAK V+GIE +S+SE S K+I  N+L DVI I     E   LPV  VD IVSEWMGYCL  E+ML +V+  RD +LK GG MFP RA L+V   E  +  D K    W+ +   Y  D+T     +M + LVD      + P  +VT       +D+Y+ +  DL      AF ++   N  +  LV +F+  F      +  ST+P    THW QT+  L   + + +   I G +   P+ + +R +    EL+
Sbjct:   93 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHLFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKSNHLDDVITIFKGKVEETELPVDQVDIIVSEWMGYCLFYESMLKTVIYARDKWLKPGGYMFPDRATLYVVAIEDRQYKDFKIH-WWENV---YGFDMTCIRNVAMMEPLVDI-----VDPKQVVTNSCLIKEVDIYTVKLEDLA--FTSAFCLQIQRNDYIHALVTYFNIEFTKCHKKTGFSTAPDAPSTHWKQTVFYLEDYLTVRRGEEILGSIAVKPNENNERDLDFTFELD 396          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Cavefish
Match: prmt1 (protein arginine methyltransferase 1 [Source:NCBI gene;Acc:103022674])

HSP 1 Score: 179.104 bits (453), Expect = 2.920e-52
Identity = 107/324 (33.02%), Postives = 171/324 (52.78%), Query Frame = 2
Query:  140 KPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            KP ++D    ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGIL +F A+AGAKKV GIE +S+S+ + K++  N L  ++ I+    E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK  GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +V+       +D+Y+ + + + +    F ++   N  +  LV +F+  F      +  STSP    THW QT+  L   + +     I G +   P+    R +   ++++
Sbjct:   32 KPAAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNKHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAVKIVKANKLDHIVTIIKGKVEEVELPVEHVDIIISEWMGYCLFYESMLNTVIYARDKWLKPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKEVAIKEPLVDV-----VDPKQLVSSACLIKEVDIYTVKIEDL-SFTSPFCLQVKRNDYIHALVTYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYLDDYLTVKTGEEIFGTISMKPNVKNNRDLDFTVDID 345          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Cavefish
Match: prmt2 (protein arginine methyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-041104-1])

HSP 1 Score: 172.555 bits (436), Expect = 1.303e-48
Identity = 104/318 (32.70%), Postives = 166/318 (52.20%), Query Frame = 2
Query:  152 DDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCAR-AGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPD------NSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIE 1084
             DE YF SY ++  H  ML+D  RT  Y++ I +  T L+G  V+D+G GTGI+S+FC R A    V+ +EA++V+E + +++  N    V+ +  S AE   LP K VD +VSEWMG CLL E M+ SVL VRD +LK+GG+M+P  A L +   + +++  +K E  W+ L   Y +D +     + ++         +L P   ++     +++D+++ +   +  L G F        T+     WFST F           L+T P  +PTHW QT+  L  PI + +   + G +    +   +R + I IE
Sbjct:  148 QDEEYFGSYGTLKLHLEMLSDRPRTETYRQVILSNSTALRGKVVMDLGCGTGIISLFCGRLAEPAAVYAVEASAVAEHTERLVKLNGCEGVVTLFKSRAEELNLPSK-VDVLVSEWMGNCLLFEFMVESVLCVRDRWLKEGGMMWPSSATLSLVPCQADDDYSQKVE-FWENL---YGLDYSCLQPVAQEEFFSKPKFSHQLKPEDCLSTPCDVITLDMHTVKVSDLEKLRGEFQFTVERRGTLHGFSAWFSTFFQSLDEGGPTLELNTGPHSEPTHWKQTLFMLDAPIPVEEGDCVGGAIILHRNPVWRRHMSITIE 460          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Cavefish
Match: prmt1 (protein arginine methyltransferase 1 [Source:NCBI gene;Acc:103022674])

HSP 1 Score: 166.777 bits (421), Expect = 4.685e-48
Identity = 99/299 (33.11%), Postives = 159/299 (53.18%), Query Frame = 2
Query:  203 MLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ML D VRTL Y+ ++   +   +   V+DVGSGTGIL +F A+AGAKKV GIE +S+S+ + K++  N L  ++ I+    E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK  GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +V+       +D+Y+ + + + +    F ++   N  +  LV +F+  F      +  STSP    THW QT+  L   + +     I G +   P+    R +   ++++
Sbjct:   11 MLKDEVRTLTYRNSMFHNKHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAVKIVKANKLDHIVTIIKGKVEEVELPVEHVDIIISEWMGYCLFYESMLNTVIYARDKWLKPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKEVAIKEPLVD-----VVDPKQLVSSACLIKEVDIYTVKIEDL-SFTSPFCLQVKRNDYIHALVTYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYLDDYLTVKTGEEIFGTISMKPNVKNNRDLDFTVDID 299          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Sea Lamprey
Match: prmt1 (protein arginine methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-030131-693])

HSP 1 Score: 179.489 bits (454), Expect = 4.280e-53
Identity = 111/315 (35.24%), Postives = 165/315 (52.38%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRP-IEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRT  Y+ A+   R   +   V+DVGSGTGIL +F A+AGAKKVFGIE +++++ S+++I  NNL  VI IV    E   L V  VD I+SEWMGYCLL E+ML +V+  RD +LK GG +FP RA LF+   E  +  + K    W+ +   Y  D++     ++Q+ LVD      + P  +VT       +D+Y+ + D +      F ++      +  LV +F+  F      +  ST+P    THW QT+  L    + +     I G +   P+    R +   I++E
Sbjct:   31 DYYFDSYAHFGIHEEMLKDEVRTRTYRNAMYHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVFGIECSNIADYSQQIIKANNLDSVITIVKGKVEEVDLLVDKVDIIISEWMGYCLLYESMLNTVICARDKWLKPGGAIFPDRASLFLTAIEDRQYKENK-INWWEDV---YGFDMSCIRDVAIQEPLVD-----VVEPKQVVTNSCLVKEVDIYTVKVDDL-TFTSPFCLQVRRADYVHALVAYFTVEFTRCHKRTGFSTAPDAPYTHWKQTVFYLKEDCLTVKPGEEIYGTISLRPNAKNNRDLDFTIDVE 335          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Sea Lamprey
Match: prmt2 (protein arginine methyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-041104-1])

HSP 1 Score: 150.214 bits (378), Expect = 2.226e-41
Identity = 95/303 (31.35%), Postives = 145/303 (47.85%), Query Frame = 2
Query:  134 ERKPCSD--------DEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCAR-AGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGE-ENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTF--PDNS---VLSTSPRDKPTHWMQTIVKLPRPI 997
            ER P  D        D+ YF SY  +     ML D VRT  Y   +   R  L+G  V+DVG G+GI+S+ CA+ A   +V+ +EA+ ++ L+ +++  N + D + ++    E   LP  +VD +VSEWMG CLL E M+ SVL  RD +L+ GG+M+P  A L +     + E  DK     WQ     Y++D +     + ++         ++ P   +      L +D+   Q   +  +   F  E      M     WFST F  PD++   +L T P    THW QT+  L  P+
Sbjct:   81 ERDPLQDLGEEDTWQDDEYFNSYSKLKLQQEMLADRVRTETYGAVMKRSRAWLRGKAVLDVGCGSGIISMLCAKHAQPSRVYAVEASELARLTEQVVRCNGMKDTVRVLQGRVEDVELP-GSVDCLVSEWMGTCLLFEFMIESVLQARDRWLRDGGVMWPSTAALHLTPCSAQREYTDKIGFWDWQ-----YELDFSQLRTEAAKEYFSKPKHDHQMDPDDCLAEPCCILQLDMSKVQTSELEEITYEFIFEVKKAGPMHGFAAWFSTEFKCPDSNPSIILDTGPMSTATHWKQTLFMLDSPV 377          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Sea Lamprey
Match: carm1 (coactivator-associated arginine methyltransferase 1 [Source:NCBI gene;Acc:445251])

HSP 1 Score: 133.265 bits (334), Expect = 2.662e-34
Identity = 91/297 (30.64%), Postives = 148/297 (49.83%), Query Frame = 2
Query:  134 ERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKK--EETLWQILSRDYDVDLT----GSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSV---LSTSPRDKPTHWMQTIVKLPRPI 997
            ER   S    YF+ Y  +     M+ D +RT  Y+RAI     + +   V+DVG G+GILS F  +AGA+KV+ +EA+S+++ +  ++  NNL D I ++    E   +P K VD I+SE MGY L  E ML S L  +  +LK  G MFP   D+ +A    E+   ++  +   W   S  + VDL+     ++    +Q +VD   +       I+  +S   +++   A+ + +  ++  F  + L +  +  L FWF   F  + +   LST+P +  THW Q    L  P+
Sbjct:  115 ERTEESSAVQYFQFYGYLSQQQNMMQDYIRTGTYQRAILQNHADFRDKIVLDVGCGSGILSFFAVQAGARKVYAVEASSMAQHAEVLVRSNNLQDRIVVIPGKVEDVSIPDK-VDVIISEPMGYMLFNERMLESYLHAK-KWLKPNGNMFPTLGDVHLAPFTDEQLYMEQFSKANFWYQQSF-HGVDLSSLRGAALEEYFRQPIVDTFDIR------ILMARSIKYTVNFQQAREEDLHRIEIPFKFQMLQSGLVHGLAFWFDVAFVGSMLTVWLSTAPTEPLTHWYQVRCLLQSPL 402          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Yeast
Match: HMT1 (Nuclear SAM-dependent mono- and asymmetric methyltransferase; modifies hnRNPs, including Npl3p and Hrp1p, affecting their activity and nuclear export; methylates U1 snRNP protein Snp1p, ribosomal protein Rps2p, and histones H3 and H4; interacts genetically with genes encoding components of Rpd3(L) and this interaction is important for Rpd3 recruitment to the subtelomeric region [Source:SGD;Acc:S000000238])

HSP 1 Score: 180.259 bits (456), Expect = 1.027e-53
Identity = 112/336 (33.33%), Postives = 171/336 (50.89%), Query Frame = 2
Query:  122 DSDDERKPCSDDE-FYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQ-ADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS-----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSV 1108
            DS  E+   S+ E  YF SY+    H  ML DTVRTL+Y+ AI   +   +   V+DVG GTGILS+F A+ GAK V G++ +S+ E+++++++ N  SD I ++    E   LP   VD I+SEWMGY LL E+M+ +VL  RD+YL +GGL+FP +  + +AG E  +  D+K    WQ        D+ G  Y+     ++   +V  +  + + T     +  DL + + +DL       F + A     ++ +V WF   FP          ST P    THW QTI   P  ++      I G +  SP+    R + I+I  +   N +
Sbjct:    8 DSATEKTKLSESEQHYFNSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEK-LNYWQ--------DVYGFDYSPFVPLVLHEPIVDTVERNNVNTTSDKLIEFDLNTVKISDLA--FKSNFKLTAKRQDMINGIVTWFDIVFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELVCSPNEKNNRDLNIKISYKFESNGI 332          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Nematostella
Match: EDO47611 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLI7])

HSP 1 Score: 181.03 bits (458), Expect = 3.167e-53
Identity = 116/351 (33.05%), Postives = 181/351 (51.57%), Query Frame = 2
Query:   59 SNADSIVTPLTNGIPLKRSRIDSDDERKPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPD---NSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            S+A + VTP+ NG     S   + D+ KP + +    ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVG GTGILS+F A+AGAK V+ IE +S+ + S+ +I +NN   VI ++    E   LPV+ VD I+SEWMGYCL  E+ML +VL  RD +LK  G++FP +A L+V   E  +   K+E+  W    R Y  D++     ++ + LVD      + P  +VT       +D+ + + + + N    F +    N  +  LV +F+  F      +  ST+P    THW QT+  L   + +     I+G +   P+    R I   I ++
Sbjct:   24 SDAVAAVTPV-NGEVNHNSSNGAKDKPKPGASEMTSADYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHLFRDKIVLDVGCGTGILSMFAAKAGAKHVYAIEMSSIVDYSKTIIKDNNFDSVITLIKGKVEDVELPVEKVDIIISEWMGYCLFYESMLDTVLYARDKWLKPDGMLFPDKAKLYVCAIEDRQY--KEEKIYW--WDRVYGFDMSSIRKVALSEPLVD-----VVDPKQVVTNSCMVKEVDIQTVKKEDL-NFTAPFRLYCHRNDYVHALVSFFTIEFTHCHKRTGFSTAPDCPYTHWKQTVFYLEDYLTVKYGEEITGSIHMEPNARNNRDIDFNIGIQ 363          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Nematostella
Match: EDO49961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RER6])

HSP 1 Score: 159.844 bits (403), Expect = 6.891e-44
Identity = 105/317 (33.12%), Postives = 160/317 (50.47%), Query Frame = 2
Query:  152 DDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADL-FVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIEL 1087
            +D  YF SY     H  ML D VRT +Y+  I       +   V+DVG GTGILS+F AR+GA++V GI+ + +   +  +I EN     I ++   AE   LPV+ VD I+SEWMGY LL E+ML +VL  RD +L   G ++P +  +  VA   GE+   K     W         D+ G   + M++++   A +  +    +++   T  SID+ S + + + N   +F  E       + +V +F   F   +    V STSP   PTHW Q I     PI ++Q  I++G +    +  E RS+ +RIE+
Sbjct:  219 EDGAYFSSYSHFGIHEEMLKDKVRTESYRDFIYGNPDIFKDKVVLDVGCGTGILSMFAARSGARQVIGIDQSEIIYQAMDIIRENGFEKTITLIKGKAEEVTLPVEQVDVIISEWMGYFLLFESMLDTVLFCRDKWLNPQGSVYPDKCTMHLVAIGTGEKKQPKI--NFWD--------DVYGFKMSCMKKTVSKEAAIETVDVDALISTHCTIKSIDINSCKKEDL-NFISSFRFEIKKPDFFTGIVSYFDIFFEHEAKEKVVFSTSPAHTPTHWKQAIFYFQNPIPVTQGQILTGHISCYKNLKEPRSLDVRIEV 524          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Nematostella
Match: EDO39146 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAV4])

HSP 1 Score: 149.828 bits (377), Expect = 3.264e-41
Identity = 112/341 (32.84%), Postives = 170/341 (49.85%), Query Frame = 2
Query:  149 SDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAG-AKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSID-LYSAQADLVRNLDG-AFNIEALGNATMSHLVFWFSTTFPD--------NS--VLSTSPRDKPTHWMQT--IVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMH 1126
             DDE YF  Y S+  H  ML D  RT +Y+ AI+      +   V+DVG GTGILS+FCAR G A KV+ +EA+ +++L+ ++I +NNL D I ++    E   LP K VD IVSEWMG  L+ E ML SVL+ RD +LK  GL++P  A LF+     +   D+    +  I    Y  D + ++  + Q+ L         +    ++     + +D L +A+ DL  +  G  F IE   ++ +     WF   F +        NS  VLST P+   THW Q   ++ +P P++ +     S  +K +P      S+     + H  N   ++ MH
Sbjct:   65 QDDE-YFADYGSLKIHLEMLKDKPRTESYRMAIEQGAGYFKDKVVLDVGCGTGILSLFCAREGKASKVYAVEASEIAKLTEEIIKQNNLDDKITVIQGKIEEVELPEK-VDIIVSEWMGTFLVFEFMLESVLTARDIWLKPNGLVWPSEAKLFLVPCCTKTAYDE----VIHIWRDQYGFDYSPAISKAKQEFLSRPIYNHVFNYEDCISTPQPIIKLDTLKTARHDLEHSAHGFEFVIEQ--DSMLYGFCSWFDVLFGNIPHGEDKRNSAVVLSTGPQCDLTHWKQDLFLLDMPLPVQENDLIKGSICLKRNPDFRRHLSVVFDFVILHPTNHRDLEVMH 397          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Nematostella
Match: EDO38718 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBZ7])

HSP 1 Score: 64.6994 bits (156), Expect = 3.127e-11
Identity = 43/121 (35.54%), Postives = 71/121 (58.68%), Query Frame = 2
Query:  194 HYTMLTDTVRTLAYKRAIDAMRTELQGA-TVIDVGSGTGILSVFCARAGAKKVFGIE-ANSVSELSRKMIDENNLSDVIEIVNSVAERAV----LPVKTVDAIVSEWMGYCLLCENMLASV 538
            H+ ML D  R LAYK+AI    +   G   V+D+GSG+GILS+F  +AGAKKV+  E + ++ ELS+ ++  N +   IE+++  +   +    LP + V  + +E +   LL E +L ++
Sbjct:  137 HFRMLNDRQRNLAYKKAISNAVS--NGCDIVLDIGSGSGILSMFAVQAGAKKVYACEMSKTMYELSKDVLLGNQMESFIEVIHKKSTDLLIGKDLPGR-VSLVCTETLDCGLLGEGILKTI 254          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Nematostella
Match: EDO28377 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6M8])

HSP 1 Score: 50.447 bits (119), Expect = 9.354e-8
Identity = 38/138 (27.54%), Postives = 66/138 (47.83%), Query Frame = 2
Query:  686 DLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNS----VLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIEL 1087
            DL G   + M++++   A +  +    +++   T  SID+ S + + + N   +F  E       + +V +F   F   +    V STSP   PTHW Q I     PI ++Q  I++G +    +  E RS+ +RIE+
Sbjct:    1 DLAGFKMSCMKKTVSKEAAIETVDVDALISTHCTIKSIDINSCKKEDL-NFISSFRFEIKKPDFFTGIVSYFDIFFEHEAKEKVVFSTSPAHTPTHWKQAIFYFQNPIPVTQGQILTGHISCYKNLKEPRSLDVRIEV 137          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Medaka
Match: prmt6 (protein arginine methyltransferase 6 [Source:NCBI gene;Acc:448867])

HSP 1 Score: 205.682 bits (522), Expect = 1.878e-62
Identity = 117/315 (37.14%), Postives = 180/315 (57.14%), Query Frame = 2
Query:  155 DEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTF-----PDNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIE 1084
            D  YF SY  +  H  M+ D VRT  Y+ AI      ++G  V+DVG+GTG+LS+FCA+AGA+KV+ +EA S+SE + K++ +NN+ D IE++    E   LP K VD IVSEWMGY LL E+ML SVL  RD +L+ GG++ P RA+L++A        D+     W  +   Y VD++     + +  +  +  V  ++   +++  +    +DLYS  A+ +R++ G F+  + G+A ++    +F+ +F     P   VLSTSP    THW Q ++ L  P E+ Q +++SG V   PS    R I I +E
Sbjct:   26 DRLYFDSYADVTIHEEMIADHVRTNTYRTAILLNTECIRGKVVLDVGAGTGVLSIFCAQAGARKVYAVEACSISEQAEKIVRQNNMDDRIEVIRGTVESVELPEK-VDVIVSEWMGYALLHESMLNSVLCARDRWLRPGGIILPSRAELYIAPICDPVVEDRLH--FWYTVKEQYGVDMSCMSDFARKCIMNSDITVNTVTVEDVLSHPARFAELDLYSVTAEELRSVKGRFSCGSFGSAAVNGFCVYFTVSFPCSDKPQTLVLSTSPFKPETHWKQAVLYLDSPAEVKQDTLVSGEVCMYPSEESDRHICIHLE 337          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Medaka
Match: ENSORLT00000020054.2 (protein arginine N-methyltransferase 8-B [Source:NCBI gene;Acc:101162208])

HSP 1 Score: 190.66 bits (483), Expect = 3.962e-56
Identity = 122/342 (35.67%), Postives = 179/342 (52.34%), Query Frame = 2
Query:   80 TPLTNGIP--LKRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            TP   G+P    R ++      +  +  ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGILS+F A+AGAK V+GIE +S+SE S K+I  N+L  VI I     E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK GGLMFP RA L+V   E  +  D K    W+ +   Y  D+T     +M++ LVD      + P  +VT       +D+Y+ + + +      F ++   N  +  LV +FS  F      +  ST+P    THW QT+  L   + + +   ISG +   P+    R +   +EL+
Sbjct:   62 TPHAAGLPGCPGRGKMAKFLTPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKSNHLDSVITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRASLYVLAIEDRQFKDFKIH-WWENV---YGFDMTCIRNVAMKEPLVDV-----VDPKQVVTNSCLVKEVDIYTVKPEDL-TFSSTFCLQIQRNDYIHALVTYFSVEFTKCHKKTGFSTAPDAAYTHWKQTVFYLEDYLTVRRGEEISGSISMKPNEKNIRDLDFTVELD 393          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Medaka
Match: prmt1 (protein arginine methyltransferase 1 [Source:NCBI gene;Acc:101173551])

HSP 1 Score: 183.341 bits (464), Expect = 5.707e-54
Identity = 110/326 (33.74%), Postives = 172/326 (52.76%), Query Frame = 2
Query:  140 KPCSDD----EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHS 1096
            KP ++D    ++YF SY     H  ML D VRTL Y+ ++   +   +   V+DVGSGTGIL +F A+AGAKKV GIE +S+S+ + K++  NN+ DV+ I+    E   LPV  VD I+SEWMGYCL  E+ML +V+  RD +LK  GL+FP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD      + P  +V+       +D+Y+ +A+ +      F ++   N  +  LV +F+  F         STSP    THW QT+  L   + +     I G +   P+    R +   ++++ +
Sbjct:   18 KPAAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFYNKHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAVKIVKANNMDDVVTIIKGKVEEVELPVDKVDIIISEWMGYCLFYESMLNTVIYARDKWLKPDGLIFPDRATLYVTAIEDRQYKDYKIH-WWENV---YGFDMSCIKEVAIKEPLVD-----VVDPKQLVSNSCLIREVDIYTVKAEDL-TFTSPFCLQVKRNDYIHALVTYFNIEFTRCHKRIGFSTSPESPYTHWKQTVFYLEDYLTVKSGEEIFGTISMKPNVKNNRDLDFTVDVDFT 333          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Medaka
Match: prmt8b (protein arginine N-methyltransferase 8-B [Source:NCBI gene;Acc:101155736])

HSP 1 Score: 183.341 bits (464), Expect = 1.964e-53
Identity = 114/314 (36.31%), Postives = 169/314 (53.82%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFP---DNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ A+   +   +   V+DVGSGTGILS+F A AGAK V+GIE +S+SE S K+I  N++ + I I     E   LPV+ VD I+SEWMGYCL  E+ML +V+  RD +LK GGLMFP RA L+V   E  +  D K    W+ +   Y  D++     ++++ LVD  VV       +VT       +D+Y+ + + + +   AF ++   N  +  LV +F+  F      +  ST+P    THW QT+  L   + + +   I G +   P+    R +   +EL+
Sbjct:   85 DYYFDSYAHFGIHEEMLKDEVRTLTYRNAMYHNKHVFKDKIVLDVGSGTGILSMFAANAGAKHVYGIECSSISEYSEKIIKSNHMHNAITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIH-WWENV---YGFDMSCIRNIAIKEPLVD--VVDHKQ---VVTNSCLLKEVDIYTVKPEDL-SFTSAFCLQIQRNHYVHALVTYFNIEFTKCHKKTGFSTAPDAPSTHWKQTVFYLEDYLTVKKGEEIFGSLSVRPNEKNVRDLEFTLELD 388          
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Medaka
Match: prmt2 (protein arginine methyltransferase 2 [Source:NCBI gene;Acc:101169075])

HSP 1 Score: 161.77 bits (408), Expect = 5.182e-45
Identity = 110/366 (30.05%), Postives = 179/366 (48.91%), Query Frame = 2
Query:   86 LTNGIPLKRSRIDSDDERKPCS-----DDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCAR-AGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDN---AVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSV------LSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDSF 1138
            +T   P +  R D+ DE +  S      DE Y+ SY ++  H  ML+D  RT  Y++ I +    L+   V+D+G GTGI+S+FCA+ A    V+ +EA+S+++ + +++  N   DV+ ++   AE   LP + VD +VSEWMG CLL E M+ SVL  RD +LK GG+M+P  A L +   +      +K  + W+   R Y +D T  + +  QQ   +    + V EL+      C    +S+D+Y+ Q   +  + G F      +        WFS  F           L+T P  +PTHW QT+  L  P+ +     I+G +    +   +R + + ++      ++R      DSF
Sbjct:   62 VTGYAPARYLREDTADEEEDASIEDPWQDEEYYGSYGTLKLHLEMLSDRSRTETYRQVIVSNSASLRNKVVMDLGCGTGIISMFCAQLAKPSAVYAVEASSMADYTGQLVKHNGCEDVVTVMKGRAEELELP-EQVDVLVSEWMGNCLLFEFMVESVLVARDRWLKDGGVMWPSSAALTLVPCQARSYYAEK-MSFWE---RPYGLDFT-PLQSLAQQEFFNKPKFSHVIELNDCLAAPCD--VISMDMYALQVRDLEEMRGEFQFSVETSGLFHGFTAWFSVHFESLETGGTTIELNTGPNSEPTHWKQTLFMLDEPVSVFSGDSITGTIGLHRNPIWRRHMTVTLQW-----NIRGQTEEADSF 414          
BLAST of Protein arginine N-methyltransferase 6 vs. Planmine SMEST
Match: SMESG000017273.1 (SMESG000017273.1)

HSP 1 Score: 737.643 bits (1903), Expect = 0.000e+0
Identity = 364/365 (99.73%), Postives = 365/365 (100.00%), Query Frame = 2
Query:   47 MNTDSNADSIVTPLTNGIPLKRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSVLSTSPRDKPTHWMQTIVKLPRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDSFL 1141
            MNTDSNADSIVTPLTNGIPLKRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRK+IDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSVLSTSPRDKPTHWMQTIVKLPRPIEISQQSIISGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDSFL
Sbjct:    1 MNTDSNADSIVTPLTNGIPLKRSRIDSDDERKPCSDDEFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKVIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSVLSTSPRDKPTHWMQTIVKLPRPIEISQQSIISGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMHFDSFL 365          
BLAST of Protein arginine N-methyltransferase 6 vs. Planmine SMEST
Match: SMESG000038804.1 (SMESG000038804.1)

HSP 1 Score: 156.377 bits (394), Expect = 7.231e-44
Identity = 101/321 (31.46%), Postives = 165/321 (51.40%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSV---LSTSPRD-KPTHWMQTIVKLPRPIEXXXXXXX----XGIVKFSPSGHEKRSIRIRIELE 1090
            ++YF SY     H  ML D VRTL Y+ A+   +  ++   V+DVG GTGIL +F  +AGA+KV GI+ +++ + ++++I  N + D I ++    E   LP  V  VD I+SEWMGYCL  E+ML +VL  RD +LK GG++ P +A L +   E  +  D+K    W+ +   Y  D++     ++ + LVD      ++P+ IV+       +++Y  + + + +    F +    N  +  LV +F+  F  +      ST P D + THW QT+  L   +  S         +GI    P+    R + I IE++
Sbjct:   20 DYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHLVKDKVVLDVGCGTGILCMFAVKAGARKVIGIDCSNIIDYAKEIIKANKMEDKITLIKGKVEEVELPDDVLKVDIIISEWMGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIEDRQYKDEK-INWWENV---YGFDMSCIRKVAVSEPLVD-----VVNPNQIVSNFCIVKEVNMYEIKVEDL-SFASPFTLAIRKNDYIHALVAFFNIDFTSSHKHIGFSTGPSDRRGTHWKQTVFYLDDGVNDSLTVNNGEEITGIFSLKPNARNNRDLDIAIEIK 330          
BLAST of Protein arginine N-methyltransferase 6 vs. Planmine SMEST
Match: SMESG000038790.1 (SMESG000038790.1)

HSP 1 Score: 152.91 bits (385), Expect = 1.286e-42
Identity = 101/333 (30.33%), Postives = 170/333 (51.05%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDN---SVLSTSP-RDKPTHWMQTIVKL----PRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMH 1126
            ++YF SY     H  ML D +RT++Y+ A+      ++   V+DVG GTGIL +F  RAGAK+V GI+ +++ + +++++  N +   I ++    E   LP  V  VD I+SEWMGYCLL E+ML +VL  RD +L  GG++ P +A L +   E  E  D+K    WQ +   Y  D++     +  + LVD      ++P  IV+       I++Y    D +      F +  L N  +  +V +F+  F  +      ST+P + + THW Q++  L       + + +   I+G+    P+    R+I + I+L+       VD+++
Sbjct:   10 DYYFDSYAHFGIHEEMLKDEIRTISYRNALYHNEHLVKDKVVLDVGCGTGILCMFAVRAGAKRVIGIDCSNIIDYAKEIVKANKMDTKITLIKGKVEEVELPADVLKVDVIISEWMGYCLLYESMLNTVLFARDKWLAPGGIIMPDKATLHMVAIEDREYKDEK-INWWQNV---YGFDMSCIRKFATSEPLVD-----VVNPDQIVSDICLVKEINMYDITVDDL-TFSTPFTLSMLRNDYVHAMVTYFNIEFTSSLKPITFSTAPTKRRATHWKQSVFYLDDGKDDTVPVKRGEEINGVFSLKPNAVNNRAIDVSIDLKFKGELKTVDKVY 332          
BLAST of Protein arginine N-methyltransferase 6 vs. Planmine SMEST
Match: SMESG000038790.1 (SMESG000038790.1)

HSP 1 Score: 152.525 bits (384), Expect = 1.559e-42
Identity = 101/333 (30.33%), Postives = 170/333 (51.05%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDN---SVLSTSP-RDKPTHWMQTIVKL----PRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMH 1126
            ++YF SY     H  ML D +RT++Y+ A+      ++   V+DVG GTGIL +F  RAGAK+V GI+ +++ + +++++  N +   I ++    E   LP  V  VD I+SEWMGYCLL E+ML +VL  RD +L  GG++ P +A L +   E  E  D+K    WQ +   Y  D++     +  + LVD      ++P  IV+       I++Y    D +      F +  L N  +  +V +F+  F  +      ST+P + + THW Q++  L       + + +   I+G+    P+    R+I + I+L+       VD+++
Sbjct:   17 DYYFDSYAHFGIHEEMLKDEIRTISYRNALYHNEHLVKDKVVLDVGCGTGILCMFAVRAGAKRVIGIDCSNIIDYAKEIVKANKMDTKITLIKGKVEEVELPADVLKVDVIISEWMGYCLLYESMLNTVLFARDKWLAPGGIIMPDKATLHMVAIEDREYKDEK-INWWQNV---YGFDMSCIRKFATSEPLVD-----VVNPDQIVSDICLVKEINMYDITVDDL-TFSTPFTLSMLRNDYVHAMVTYFNIEFTSSLKPITFSTAPTKRRATHWKQSVFYLDDGKDDTVPVKRGEEINGVFSLKPNAVNNRAIDVSIDLKFKGELKTVDKVY 339          
BLAST of Protein arginine N-methyltransferase 6 vs. Planmine SMEST
Match: SMESG000038790.1 (SMESG000038790.1)

HSP 1 Score: 149.058 bits (375), Expect = 3.262e-41
Identity = 101/333 (30.33%), Postives = 170/333 (51.05%), Query Frame = 2
Query:  158 EFYFKSYESMDSHYTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKKVFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLP--VKTVDAIVSEWMGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKEETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALSIDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDN---SVLSTSP-RDKPTHWMQTIVKL----PRPIEXXXXXXXXGIVKFSPSGHEKRSIRIRIELEHSDNSVRVDQMH 1126
            ++YF SY     H  ML D +RT++Y+ A+      ++   V+DVG GTGIL +F  RAGAK+V GI+ +++ + +++++  N +   I ++    E   LP  V  VD I+SEWMGYCLL E+ML +VL  RD +L  GG++ P +A L +   E  E  D+K    WQ +   Y  D++     +  + LVD      ++P  IV+       I++Y    D +      F +  L N  +  +V +F+  F  +      ST+P + + THW Q++  L       + + +   I+G+    P+    R+I + I+L+       VD+++
Sbjct:   10 DYYFDSYAHFGIHEEMLKDEIRTISYRNALYHNEHLVKDKVVLDVGCGTGILCMFAVRAGAKRVIGIDCSNIIDYAKEIVKANKMDTKITLIKGKVEEVELPADVLKVDVIISEWMGYCLLYESMLNTVLFARDKWLAPGGIIMPDKATLHMVAIEDREYKDEK-INWWQNV---YGFDMSCIRKFATSEPLVD-----VVNPDQIVSDICLVKEINMYDITVDDL-TFSTPFTLSMLRNDYVHAMVTYFNIEFTSSLKPITFSTAPTKRRATHWKQSVFYLDDGKDDTVPVKRGEEINGVFSLKPNA---RAIDVSIDLKFKGELKTVDKVY 329          
The following BLAST results are available for this feature:
BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRMT86.847e-5736.62protein arginine methyltransferase 8 [Source:HGNC ... [more]
PRMT81.190e-5636.62protein arginine methyltransferase 8 [Source:HGNC ... [more]
PRMT63.021e-5635.06protein arginine methyltransferase 6 [Source:HGNC ... [more]
PRMT14.785e-5332.86protein arginine methyltransferase 1 [Source:HGNC ... [more]
PRMT12.773e-5233.43protein arginine methyltransferase 1 [Source:HGNC ... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
prmt-18.031e-4632.41Protein arginine N-methyltransferase 1 [Source:Un... [more]
prmt-18.031e-4632.41Protein arginine N-methyltransferase 1 [Source:Un... [more]
prmt-78.605e-623.66Protein arginine N-methyltransferase 7 [Source:Un... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Art11.466e-5334.81gene:FBgn0037834 transcript:FBtr0082304[more]
Art67.141e-4631.04gene:FBgn0038189 transcript:FBtr0082878[more]
Art82.334e-4535.00gene:FBgn0032329 transcript:FBtr0080162[more]
Art36.218e-4334.39gene:FBgn0038306 transcript:FBtr0083135[more]
Art31.297e-4234.39gene:FBgn0038306 transcript:FBtr0083134[more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prmt62.036e-5934.69protein arginine methyltransferase 6 [Source:NCBI ... [more]
prmt8b5.419e-5736.62protein arginine methyltransferase 8b [Source:NCBI... [more]
prmt8b7.503e-5636.62protein arginine methyltransferase 8b [Source:NCBI... [more]
prmt8b7.681e-5636.62protein arginine methyltransferase 8b [Source:NCBI... [more]
PRMT82.586e-5436.31protein arginine N-methyltransferase 8-B-like [Sou... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prmt62.207e-6438.97protein arginine methyltransferase 6 [Source:NCBI ... [more]
PRMT82.759e-5533.92protein arginine methyltransferase 8 [Source:NCBI ... [more]
il1rap2.728e-5432.68interleukin 1 receptor accessory protein [Source:X... [more]
il1rap2.172e-5332.67interleukin 1 receptor accessory protein [Source:X... [more]
il1rap4.502e-5333.33interleukin 1 receptor accessory protein [Source:X... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Prmt85.701e-5736.94protein arginine N-methyltransferase 8 [Source:MGI... [more]
Prmt68.095e-5735.33protein arginine N-methyltransferase 6 [Source:MGI... [more]
Prmt68.095e-5735.33protein arginine N-methyltransferase 6 [Source:MGI... [more]
Prmt68.095e-5735.33protein arginine N-methyltransferase 6 [Source:MGI... [more]
Prmt12.444e-5332.86protein arginine N-methyltransferase 1 [Source:MGI... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|B0JYW5|ANM6_XENTR6.937e-6539.27Protein arginine N-methyltransferase 6 OS=Xenopus ... [more]
sp|Q68EZ3|ANM6_XENLA1.705e-6437.46Protein arginine N-methyltransferase 6 OS=Xenopus ... [more]
sp|Q6NWG4|ANM6_DANRE1.379e-5834.69Protein arginine N-methyltransferase 6 OS=Danio re... [more]
sp|Q6PAK3|ANM8_MOUSE3.988e-5636.94Protein arginine N-methyltransferase 8 OS=Mus musc... [more]
sp|Q6NZB1|ANM6_MOUSE5.662e-5635.33Protein arginine N-methyltransferase 6 OS=Mus musc... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2R5LAC58.746e-6436.45Protein arginine n-methyltransferase prmt1 (Fragme... [more]
A0A3B4CE104.314e-6337.39Protein arginine methyltransferase 6 OS=Pygocentru... [more]
A0A0C9S2P83.240e-6236.31Protein arginine n-methyltransferase prmt1 (Fragme... [more]
A0A060Y6B73.329e-6236.62Uncharacterized protein OS=Oncorhynchus mykiss OX=... [more]
W5LU863.446e-6235.38Protein arginine methyltransferase 6 OS=Astyanax m... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prmt61.305e-6535.38protein arginine methyltransferase 6 [Source:NCBI ... [more]
prmt8b1.710e-5637.78protein arginine N-methyltransferase 8-B [Source:N... [more]
prmt12.920e-5233.02protein arginine methyltransferase 1 [Source:NCBI ... [more]
prmt21.303e-4832.70protein arginine methyltransferase 2 [Source:ZFIN;... [more]
prmt14.685e-4833.11protein arginine methyltransferase 1 [Source:NCBI ... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
prmt14.280e-5335.24protein arginine methyltransferase 1 [Source:ZFIN;... [more]
prmt22.226e-4131.35protein arginine methyltransferase 2 [Source:ZFIN;... [more]
carm12.662e-3430.64coactivator-associated arginine methyltransferase ... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
HMT11.027e-5333.33Nuclear SAM-dependent mono- and asymmetric methylt... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO476113.167e-5333.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO499616.891e-4433.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO391463.264e-4132.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO387183.127e-1135.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO283779.354e-827.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prmt61.878e-6237.14protein arginine methyltransferase 6 [Source:NCBI ... [more]
ENSORLT00000020054.23.962e-5635.67protein arginine N-methyltransferase 8-B [Source:N... [more]
prmt15.707e-5433.74protein arginine methyltransferase 1 [Source:NCBI ... [more]
prmt8b1.964e-5336.31protein arginine N-methyltransferase 8-B [Source:N... [more]
prmt25.182e-4530.05protein arginine methyltransferase 2 [Source:NCBI ... [more]
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BLAST of Protein arginine N-methyltransferase 6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017273.10.000e+099.73SMESG000017273.1[more]
SMESG000038804.17.231e-4431.46SMESG000038804.1[more]
SMESG000038790.11.286e-4230.33SMESG000038790.1[more]
SMESG000038790.11.559e-4230.33SMESG000038790.1[more]
SMESG000038790.13.262e-4130.33SMESG000038790.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30016088 ID=SMED30016088|Name=Protein arginine N-methyltransferase 6|organism=Schmidtea mediterranea sexual|type=transcript|length=1217bp
TTTACATTTTTTAACGTGATTACAAATTTGCAAATTTTCATTCTAAATGA
ATACAGATTCGAACGCGGACAGCATTGTAACTCCATTGACAAATGGCATC
CCATTGAAGCGATCAAGAATTGATAGTGATGATGAGAGAAAGCCTTGCAG
TGACGATGAATTTTATTTTAAATCATACGAGTCGATGGATTCCCACTACA
CGATGCTGACGGACACCGTGCGCACCCTCGCATACAAACGGGCAATCGAT
GCCATGAGAACCGAGCTGCAGGGGGCCACCGTGATCGATGTCGGTAGCGG
AACCGGAATCCTCAGCGTGTTCTGCGCACGCGCCGGCGCCAAAAAAGTTT
TCGGGATTGAGGCTAACTCGGTGAGCGAGCTGAGCCGGAAAATGATCGAT
GAAAACAATCTATCCGACGTTATTGAAATCGTCAACAGCGTCGCTGAGAG
AGCTGTGCTGCCCGTCAAAACCGTCGATGCGATAGTCAGCGAGTGGATGG
GATATTGCCTGCTGTGCGAGAACATGCTGGCGTCCGTGCTGTCCGTGCGC
GATAACTACCTGAAAAAGGGTGGCCTGATGTTCCCGTGCCGGGCAGATCT
GTTTGTTGCGGGCGCCGAGGGCGAGGAAAACGCAGACAAGAAGGAAGAAA
CGCTGTGGCAGATTTTGTCGCGCGATTACGATGTCGATTTGACGGGCTCG
GTTTACACGAGCATGCAGCAGTCGCTGGTCGATAACGCGGTTGTCGCGGA
GCTGTCGCCCCATTTCATCGTCACTTGCAAGAGCACCGCGCTCTCGATCG
ATCTCTATTCCGCTCAGGCTGACCTTGTCCGTAACCTTGACGGCGCATTC
AATATTGAGGCACTCGGGAACGCCACAATGAGCCATTTGGTGTTCTGGTT
CTCCACGACCTTCCCTGACAACTCGGTGTTGTCAACGAGCCCCCGTGACA
AGCCCACTCATTGGATGCAAACGATCGTCAAGTTGCCTCGACCAATAGAA
ATCAGCCAACAATCCATCATTTCAGGAATCGTGAAATTCAGCCCCTCAGG
TCACGAGAAGCGCAGCATTCGAATCAGAATCGAGCTGGAACACTCGGACA
ATTCAGTCAGAGTCGACCAAATGCATTTCGATAGCTTTTTGTAGTGATCG
ATTTGCATTGGCCATTGCGCAACGATTACGGATGGTGTTATGTAATAATA
AATTGTATTGTCGTTGA
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protein sequence of SMED30016088-orf-1

>SMED30016088-orf-1 ID=SMED30016088-orf-1|Name=SMED30016088-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=366bp
MNTDSNADSIVTPLTNGIPLKRSRIDSDDERKPCSDDEFYFKSYESMDSH
YTMLTDTVRTLAYKRAIDAMRTELQGATVIDVGSGTGILSVFCARAGAKK
VFGIEANSVSELSRKMIDENNLSDVIEIVNSVAERAVLPVKTVDAIVSEW
MGYCLLCENMLASVLSVRDNYLKKGGLMFPCRADLFVAGAEGEENADKKE
ETLWQILSRDYDVDLTGSVYTSMQQSLVDNAVVAELSPHFIVTCKSTALS
IDLYSAQADLVRNLDGAFNIEALGNATMSHLVFWFSTTFPDNSVLSTSPR
DKPTHWMQTIVKLPRPIEISQQSIISGIVKFSPSGHEKRSIRIRIELEHS
DNSVRVDQMHFDSFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006325chromatin organization
GO:0018216peptidyl-arginine methylation
GO:0035246peptidyl-arginine N-methylation
GO:0006479protein methylation
GO:0006281DNA repair
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0006974cellular response to DNA damage stimulus
GO:0016569covalent chromatin modification
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0032259methylation
GO:0034970histone H3-R2 methylation
GO:0043985histone H4-R3 methylation
GO:0045892negative regulation of transcription, DNA-templated
Vocabulary: molecular function
TermDefinition
GO:0008469histone-arginine N-methyltransferase activity
GO:0016274protein-arginine N-methyltransferase activity
GO:0008168methyltransferase activity
GO:0016740transferase activity
GO:0035241protein-arginine omega-N monomethyltransferase activity
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity
GO:0042054histone methyltransferase activity
GO:0042393histone binding
GO:0044020histone methyltransferase activity (H4-R3 specific)
GO:0070611histone methyltransferase activity (H3-R2 specific)
GO:0070612histone methyltransferase activity (H2A-R3 specific)
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR029063SAM-dependent_MTases
IPR025799Arg_MeTrfase
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePFAMPF06325PrmAcoord: 73..149
e-value: 6.1E-8
score: 32.4
NoneNo IPR availableGENE3DG3DSA:2.70.160.11coord: 182..362
e-value: 3.4E-30
score: 107.2
NoneNo IPR availableGENE3DG3DSA:3.40.50.150coord: 29..180
e-value: 4.5E-49
score: 168.2
NoneNo IPR availablePANTHERPTHR11006:SF73PROTEIN ARGININE N-METHYLTRANSFERASE 6coord: 35..353
NoneNo IPR availablePANTHERPTHR11006PROTEIN ARGININE N-METHYLTRANSFERASEcoord: 35..353
NoneNo IPR availableCDDcd02440AdoMet_MTasescoord: 78..179
e-value: 1.38281E-8
score: 50.1211
IPR025799Protein arginine N-methyltransferasePROSITEPS51678SAM_MT_PRMTcoord: 37..342
score: 59.144
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILYSSF53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 43..352