myosin-11

Overview
Namemyosin-11
Smed IDSMED30015973
Length (bp)1768
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of myosin-11 (SMED30015973) t-SNE clustered cells

Violin plots show distribution of expression levels for myosin-11 (SMED30015973) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of myosin-11 (SMED30015973) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for myosin-11 (SMED30015973) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30015973

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
headSMED30015973SMESG000064787.1 SmedASXL_009190SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30015973SMESG000064787.1 dd_Smed_v4_13489_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30015973SMESG000064787.1 dd_Smed_v4_13489_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
epidermal cellSMED30015973SMESG000064787.1 dd_Smed_v4_13489_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
headSMED30015973SMESG000064787.1 dd_Smed_v6_13489_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30015973SMESG000064787.1 dd_Smed_v4_13489_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
ciliated epithelial cellSMED30015973SMESG000064787.1 dd_Smed_v4_13489_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of myosin-11 vs. TrEMBL
Match: A0A1S3KCX9 (myosin-11 OS=Lingula unguis OX=7574 GN=LOC106180864 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 3.232e-27
Identity = 144/538 (26.77%), Postives = 267/538 (49.63%), Query Frame = 1
Query:   46 SKYEIIWKSLSEPNIITNSD------CEYASFLKNLERTCNKTGYLDSKFYTQQFNSIKSNPSDKKSDTKTAVHPHEIARYRNKFSED---YEKQMKRISRAXXXXXXXXXXXXXXXGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSXXXXXXXXXXXXXXXKSKEDEDKVTETSLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENAXXXXXXXXXXXXXXXIEEVSSRKLTMANISQSDLIKKRAENEQKYVQLSTNRQILMDLENAAENADHLKETVRRDKENEKKYFKKMNDSSKDIKQLSTTISRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSD 1632
            S+Y  I +  S P      D       EYA+FLK  ER C   G+LDS  YT  FN       + KS       P  +     K  +D   YEK+++ +   + + K++ER LKR EGDI+K +  + +SL +F+  I  K+F +D + N   E+   +Q+   + K +  K+R  KS+        K R+ ++  S L R++ +K +E+++   ++  +  EF++++ ++E +  +L+ EL   S +L  E  K ++ +E  QR+ + + K + DED   + +L   L  SD+ +KTA + R+ L   L       ++K  E G  L   + +L +  N QRQL + A +  L LK  + ++ +    +RK++    +  +  +K    E +Y +    R I        ++  H ++TV + +E E   + K+ ++    ++   T+ RL  +L + K  N+ ++ EE  +  KLE+++++EL R    L ++  +R     QL + R+ ++ D++ L + E    RL ++  KS+
Sbjct:   16 SRYMSIKRPGSPPPDSDEEDEKSKEAKEYAAFLKETERKCGPDGFLDSSKYTHTFNV-----KEGKSPRSPGATPRSVVDLAQKIEQDQKDYEKRIRLVEDHMWQHKQEERELKRVEGDIIKNQRSVRRSLKDFEQAIAKKRFLEDRKFNQGMEKYTNLQRDHVHQKEELTKQRTEKSISFDNSLKDKGRKVELAKSDLARKYKSKMSEMELRRIELMKIQQEFDLKMKKKEEEQFRLKQELAELSISLNMEAQKGRSIKEDAQRDSKKENKQRIDEDLTMQRTLDHKLTKSDSNVKTALMNRRKLSADLTLTKAHLNLKGREEGRHLQDTQIRLEDNSNIQRQLNQAALHAELDLKAKQIEQNLHAHDARKVSRLRQAVKEKKEKSEIMENQYSERFQKRFIEARRREHEDHLRHFQKTVTKAEEYEHSLYNKVREAEYARQKQEQTVRRLQNKLLEAKRKNAVKLKEEMVTIQKLEEELQQELVREKAALDKVHARREESYIQLQKHRQTMREDKHNLNEHEREHMRLLRVGAKSE 548          
BLAST of myosin-11 vs. TrEMBL
Match: A0A210PFC8 (Uncharacterized protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05405 PE=4 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 1.216e-17
Identity = 151/567 (26.63%), Postives = 281/567 (49.56%), Query Frame = 1
Query:    1 IYINLIW*HNKMIESSKYEIIWKSLSEPNIITNSD-------CEYASFLKNLERTCNKTGYLDSKFYTQQFNSIKSNPSDKK----SDTKTAVHPHEIA--RYRNKFSEDYEKQMKRISRAX-------XXXXXXXXXXXXXXGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSXXXXXXXXXXXXXXXKSKEDEDKVTETSLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENAXXXXXXXXXXXXXXXIEEVSSRKLTMANISQSDLIKKRAENEQKYVQLSTNRQILMDLENAAENADHLK---ETVRRDKENEKKYFKKMNDSSKDIKQLSTTISRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSD 1632
            +  +L + H  +I S +Y  I +  S P  I   +         YA+FL+  ER     G+LDS  Y+  F  +K + S +K    +D+     P  +A      K  +D++K+MK I            + K++ER LKR EGDI+K +  +  +L +F++ IN K+ Q++ +LN   E   KI++ F + K    K R++ ++ +      + R+ ++  S L R++ +K +EL++   ++  +  +FE ++ + E +   LQNEL   S  L  E  K +  + + +RE +  Q +K  E+     ++   L  SD   K AE+ ++ L   L+   +   +K  +    L   + +L +  N QRQL E A + NL +K  +  +K+E  ++R++     + SD  KK  E+E++ V  S  ++   +     E+ D LK   + V +  + E+  + K+ +S    ++   T+ RL + L D K  NS +I +E     + E++++E+L R   +L +   +R     +L + R+ LK D++ L++ E   +R+ +I E+SD
Sbjct:    2 VLTDLPFEHGALIHS-RYTTIRRPDSAPAGIKEDEERRQRQTKSYATFLREQERKVGPEGFLDSSRYSHSF-VVKKDKSKQKLRKSADSGIPSRPSVVAFSARVEKDGKDHKKRMKVIEEGQMSLRDHMWQHKQEERELKRVEGDIIKNQRAVRHTLRDFENAINKKRMQEEKKLNQGLEVYTKIRRDFVHKKEDLTKTRIQHTMSTEHNTKWQGRKNEVQQSDLSRKYRSKVSELELKRIEVLRMNQDFETKMRQTEEEQLNLQNELAELSINLNMESQKGRVMRFESERERKKNQTNKIQENLQGVDNVKNKLMRSDGDTKAAEMNKRKLSADLSLTKSHLDIKKRDEQRHLTDTQFRLDDNSNIQRQLNEAAFHANLDMKARQIDQKLEAHNARRINKLVSTMSD--KKMKEDEKQAVWESRFKRRYNE-HKRKEHDDQLKFFQKMVVKGDDCEQSLYNKVRNSEYTRQKQEQTVRRLQQTLADVKRKNSVKIRQELSERQREEKELQEKLIREKAELDKAHAQREESYIKLQQHRQLLKEDKHNLKEHERENARILKISERSD 563          
BLAST of myosin-11 vs. TrEMBL
Match: A0A2C9LWJ2 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106075175 PE=4 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 5.622e-17
Identity = 136/546 (24.91%), Postives = 268/546 (49.08%), Query Frame = 1
Query:   46 SKYEIIWKSLSEPNIITNSD---------CEYASFLKNLERTCNKTGYLDSKFYTQQFNSIKS-NPSDKKSDTKTAVHPHEIARYRNKFSE---DYEKQMKRISRAXXXXXXXXXXXXXXXGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSXXXXXXXXXXXXXXXKSKEDEDKVTETSLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENAXXXXXXXXXXXXXXXIEEVSSRKL-TMANISQSDLIKKRAEN---EQKYVQLSTNRQILMDLENAAENADHLKETVRRDKENEKKYFKKMNDSSKDIKQLSTTISRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSD 1632
            S+Y +I +  S PN   + +          EYA+FLK  ER    +G+LDS  Y+  ++  K  + +  +S ++    P  +  + +   +   DY+K+M+ I   + + K++ER LKR EGDI+K + ++  +L ++++ +N KKF ++ +LN + E    + ++  + K +  K+R   ++  ++ + G  R+  + +S L R + AK+  +++   ++  L  +FE +L  +E +  +L+ EL   +  L  E  K++  + + ++E + ++     ED   + +L   L +S+N IK + + +  LD  L    +   +K  +    L   + +L    N QR+L  +A +  L LK    + K++  + R+L  + N  Q    K+ AEN   EQK+ +    RQ+        +      + V + +E E+  F  +  +  + KQ   ++ RL   L + K +N+++I EE     + E+  + +L +  ++L ++   R     +L + R  LK D+  LQ  E    RL +I +KSD
Sbjct:   16 SRYNLIRRPESAPNPFISKEEERNDAEETKEYAAFLKAQERKVGPSGFLDSNRYSYTYSLKKDKHKTTPRSKSRYGTTPENVVLFSSYMQDNEKDYQKKMRVIEDHMWQHKQEERELKRIEGDIIKNQRLVRHTLRDYENAVNKKKFSEEKKLNHSLERFTLMSREHLHKKEEESKKRTLCNITDNLAQKGTSRRQYLRLSDLERLYIAKRTAIELKRSEVLRLSQDFEAKLRHKEQEQHRLKQELADLAITLNLETQKARVHKFEFKKEKEKEKTDHIQEDLSAQNTLEKNLMNSNNDIKASMMSKNQLDMDLAVTKSHLEIKKRDEQRHLTDTQIQLNNNSNAQRKLNNSAVFAGLDLKAKNIEHKVDVHNKRRLFKLRNYVQEKTEKESAENVVLEQKFKE----RQLEAQRYKHEDALKFFSKMVNKGEEKEQSLFSTVRTAEYNRKQQEHSVHRLQNSLAELKRINANKIKEEMVERQRNEETAQHKLLKEKSELDKVHALREESYWKLLDHRVRLKEDKLLLQDYEKEHQRLLKIGQKSD 557          
BLAST of myosin-11 vs. TrEMBL
Match: V4AWX8 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_239135 PE=4 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 3.157e-16
Identity = 156/605 (25.79%), Postives = 288/605 (47.60%), Query Frame = 1
Query:    1 IYINLIW*HNKMIESSKYEIIWKSLSEPNIITNSDCE---------------YASFLKNLERTCNKTGYLDSKFYTQQFNSIKSNPSDKKSDTKTAVHPHEIARYRNKFSED---YEKQMKRISRAXXXXXXXXXXXXXXXGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDK--------------------------SKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSXXXXXXXXXXXXXXXKSKEDEDKVTETSLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENAXXXXXXXXXXXXXXXIEEVSSRKLTMANISQSDLIKKRAENEQKYVQLSTNRQILMDLENAAENADHLKETVRRDKENEKKYFKKMNDSSKDIKQ-LSTTI--------------SRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSDQV 1638
            +  NL +  N +++S +Y +I +  S P I+T S  +               YASFLK  ER     G++DS  Y+  +   K NP    S  +  +    I  +RN   ED   +EK +K I   + + K++ER LKR EGDIVK +  +  +L ++++ IN KK  +  +L+ + E+   +Q+   ++K                           KT   R++KS  +++      R+ D+  + L R++ +K +E+++   +++ L  E+E +L  +EN+  +L+ E    + +L  E +K +T+Q +  R+ +  +K + ++D   +   S  L  SD  IKT E   + L   L++  +   +K  +    L   + +L    NTQR L E A    +  K  +  ++++E + R++   N  QS+L +K+ + E        N+Q +++    A     L E  RR+ E+  K+F+KM +   DI+Q L + +               RL   L + K  N++++ +E    +  E Q+E+++ R   +L +L TKR     +L + R+  K D+Y L++ E   +RL +I  K++ V
Sbjct:    2 VLTNLPFERNSLLQS-RYHLIQRPDSAP-IVTKSIRQSGEHVENEKGKQAKNYASFLKEQERKVCPDGFVDSGRYSYTYQRKKDNPLRSSSSPRIDL----ITFHRNA-EEDGTKHEKCLKVIEDLMWQHKQQERELKRTEGDIVKNQQAVRHTLRDYENAINKKKMAESKKLSHSLEKYTILQQDHIHNKEQLILEQFMICGKVSFTLILEQFIISGKTTLARIQKSQSTNLSIKDDGRKVDLTKTDLARKYRSKLSEIELKRTEVNRLNEEYENKLKLKENEEFRLKQEAAALALSLNMETVKGKTKQIETARKKKEDEKKRIEDDLNNDMEFSSKLAKSDGDIKTTESYNRKLSADLSRTKHHLDIKKRDEQRRLTDTKMRLANNTNTQRLLNEEAINVEMDKKVREMNQRVQEHNDRRI---NQLQSNLKEKKVKRE--------NQQSILE----ARFKKRLNEQQRREHEDSLKFFQKMVNKDDDIEQDLYSKVRATEYDRQQQEQQVRRLELNLAEMKRKNAAKLKQEINERNTAELQLEQKILRDKAELEKLHTKREESYLRLQQHRQLSKEDKYLLREHEREHTRLMRIGAKTETV 584          
BLAST of myosin-11 vs. TrEMBL
Match: A0A2C9LWJ1 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106075175 PE=4 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 3.213e-15
Identity = 135/546 (24.73%), Postives = 265/546 (48.53%), Query Frame = 1
Query:   46 SKYEIIWKSLSEPNIITNSD---------CEYASFLKNLERTCNKTGYLDSKFYTQQFNSIKS-NPSDKKSDTKTAVHPHEIARYRNKFSE---DYEKQMKRISRAXXXXXXXXXXXXXXXGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSXXXXXXXXXXXXXXXKSKEDEDKVTETSLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENAXXXXXXXXXXXXXXXIEEVSSRKL-TMANISQSDLIKKRAEN---EQKYVQLSTNRQILMDLENAAENADHLKETVRRDKENEKKYFKKMNDSSKDIKQLSTTISRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSD 1632
            S+Y +I +  S PN   + +          EYA+FLK  ER    +G+LDS  Y+  ++  K  + +  +S ++    P  +  + +   +   DY+K+M+ I   + + K++ER LKR EGDI+K + ++  +L ++++ +N KKF ++ +LN + E    + ++  + K +  K+    S    +    + R+ ++ +S L R + AK+  +++   ++  L  +FE +L  +E +  +L+ EL   +  L  E  K++  + + ++E + ++     ED   + +L   L +S+N IK + + +  LD  L    +   +K  +    L   + +L    N QR+L  +A +  L LK    + K++  + R+L  + N  Q    K+ AEN   EQK+ +    RQ+        +      + V + +E E+  F  +  +  + KQ   ++ RL   L + K +N+++I EE     + E+  + +L +  ++L ++   R     +L + R  LK D+  LQ  E    RL +I +KSD
Sbjct:   16 SRYNLIRRPESAPNPFISKEEERNDAEETKEYAAFLKAQERKVGPSGFLDSNRYSYTYSLKKDKHKTTPRSKSRYGTTPENVVLFSSYMQDNEKDYQKKMRVIEDHMWQHKQEERELKRIEGDIIKNQRLVRHTLRDYENAVNKKKFSEEKKLNHSLERFTLMSREHLHKKEENDKQEFLDSHNETLAYNSQARKLELQLSDLERLYIAKRTAIELKRSEVLRLSQDFEAKLRHKEQEQHRLKQELADLAITLNLETQKARVHKFEFKKEKEKEKTDHIQEDLSAQNTLEKNLMNSNNDIKASMMSKNQLDMDLAVTKSHLEIKKRDEQRHLTDTQIQLNNNSNAQRKLNNSAVFAGLDLKAKNIEHKVDVHNKRRLFKLRNYVQEKTEKESAENVVLEQKFKE----RQLEAQRYKHEDALKFFSKMVNKGEEKEQSLFSTVRTAEYNRKQQEHSVHRLQNSLAELKRINANKIKEEMVERQRNEETAQHKLLKEKSELDKVHALREESYWKLLDHRVRLKEDKLLLQDYEKEHQRLLKIGQKSD 557          
BLAST of myosin-11 vs. Planmine SMEST
Match: SMESG000064787.1 (SMESG000064787.1)

HSP 1 Score: 986.482 bits (2549), Expect = 0.000e+0
Identity = 540/543 (99.45%), Postives = 541/543 (99.63%), Query Frame = 1
Query:   34 MIESSKYEIIWKSLSEPNIITNSDCEYASFLKNLERTCNKTGYLDSKFYTQQFNSIKSNPSDKKSDTKTAVHPHEIARYRNKFSEDYEKQMKRISRAXXXXXXXXXXXXXXXGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSXXXXXXXXXXXXXXXKSKEDEDKVTETSLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENAXXXXXXXXXXXXXXXIEEVSSRKLTMANISQSDLIKKRAENEQKYVQLSTNRQILMDLENAAENADHLKETVRRDKENEKKYFKKMNDSSKDIKQLSTTISRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSDQVQHFLPNVV 1662
            MIESSKYEIIWKSLSEPNIITNSDCEYASFLKNLERTCNKTGYLDSKFYTQQFNSIKSNPSDKKSDTKTAVHPHEIARYRNKFSEDYEKQMKRISRALLEEKRKERLLKRREGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSQTQQEQMQRELQLQQKSKEDEDKVTE SLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENANYYNLVLKNTKNKKKIEEVSSRKLTMANISQSDLIKKRAENEQKYVQLSTNRQILMDLENAAENADHLKETVRRDKENEK+YFKKMNDSSKDIKQLSTTISRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSDQVQ FLPNVV
Sbjct:    1 MIESSKYEIIWKSLSEPNIITNSDCEYASFLKNLERTCNKTGYLDSKFYTQQFNSIKSNPSDKKSDTKTAVHPHEIARYRNKFSEDYEKQMKRISRALLEEKRKERLLKRREGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEELEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNAKKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIKSQTQQEQMQRELQLQQKSKEDEDKVTERSLSLFLNHSDNGIKTAELERKTLDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENANYYNLVLKNTKNKKKIEEVSSRKLTMANISQSDLIKKRAENEQKYVQLSTNRQILMDLENAAENADHLKETVRRDKENEKRYFKKMNDSSKDIKQLSTTISRLSKQLHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQLAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSDQVQPFLPNVV 543          
The following BLAST results are available for this feature:
BLAST of myosin-11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3KCX93.232e-2726.77myosin-11 OS=Lingula unguis OX=7574 GN=LOC10618086... [more]
A0A210PFC81.216e-1726.63Uncharacterized protein OS=Mizuhopecten yessoensis... [more]
A0A2C9LWJ25.622e-1724.91Uncharacterized protein OS=Biomphalaria glabrata O... [more]
V4AWX83.157e-1625.79Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A0A2C9LWJ13.213e-1524.73Uncharacterized protein OS=Biomphalaria glabrata O... [more]
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BLAST of myosin-11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of myosin-11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000064787.10.000e+099.45SMESG000064787.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015973 ID=SMED30015973|Name=myosin-11|organism=Schmidtea mediterranea sexual|type=transcript|length=1768bp
ATCTATATAAATCTTATATGGTAGCACAACAAAATGATCGAATCTAGTAA
GTACGAAATCATTTGGAAAAGTCTCAGCGAACCTAATATTATTACGAACT
CTGATTGCGAATATGCATCATTTTTAAAAAATTTAGAGCGAACATGCAAC
AAAACAGGCTATTTAGATTCAAAATTCTATACTCAGCAATTTAACTCTAT
CAAATCAAATCCCAGTGATAAAAAGTCTGATACAAAAACAGCCGTTCATC
CACATGAAATCGCCAGGTATAGAAATAAATTCAGTGAAGATTATGAAAAG
CAAATGAAAAGAATTAGTAGAGCACTTCTTGAAGAGAAGAGAAAAGAAAG
ACTTCTCAAAAGAAGAGAAGGAGATATTGTGAAAAAAGAACACGTTCTGA
ATAAATCATTATTCGAGTTCGATTCAGAAATCAATTCCAAGAAATTTCAA
CAAGATTTACAGTTAAATGTAACAGCAGAAGAGTTGGAAAAAATTCAAAA
AAAGTTTTACTATGATAAATCAAAAACAATAAAAGAAAGAATGAGAAAAT
CAGTTTTCAGTCATGTTGAAAAAGCTGGAAAATTAAGACAAGCTGATATG
AATGTTTCTAAATTGATAAGAGAATTCAATGCCAAGAAAAACGAATTAGA
TGTTAATGCAAAGGATATCTCAAATTTGATGCACGAATTCGAAATTCAAT
TGATGCGTGAAGAAAATAAACATAAAAAACTTCAAAATGAACTGGAAATT
TATTCTCAGGCGTTGAGAAGAGAGATTATTAAAAGCCAAACTCAGCAGGA
GCAAATGCAAAGGGAATTACAATTGCAACAAAAAAGTAAAGAAGATGAAG
ATAAGGTAACAGAAACATCGCTCTCACTTTTCCTGAACCATTCGGATAAT
GGAATCAAAACAGCAGAATTAGAACGGAAAACTTTAGATGGCCAATTGAA
CAAGATGGTTAACGAACATTCAGTGAAGATCTGTGAATATGGGGGATCTT
TAAACACGATTCGCAACAAATTGCGAGAATGTGAAAACACTCAACGTCAA
CTCATAGAAAATGCAAATTATTATAATTTGGTTTTGAAAAATACCAAAAA
CAAAAAAAAAATAGAAGAAGTTAGTTCTAGAAAACTCACAATGGCTAATA
TCAGTCAAAGTGATTTAATTAAAAAAAGAGCTGAAAATGAACAGAAATAT
GTTCAACTTTCTACAAACAGACAAATTCTAATGGATCTCGAGAATGCAGC
GGAGAATGCAGATCATTTGAAAGAAACCGTTCGGAGAGATAAAGAAAATG
AGAAGAAGTATTTTAAAAAAATGAATGATTCGAGCAAGGATATTAAGCAA
TTGTCAACTACGATAAGTCGGCTATCCAAGCAGTTGCATGACACGAAAGT
CCTTAATTCAAGTCGTATTAATGAAGAAAAGAGAAGCGCGGACAAATTAG
AGCAGCAAATGGAAGAAGAATTAAACAGGCTGAACACGCAATTAATTGAA
TTACAAACGAAGAGAAATAATCATTGTAACCAACTTGCTGAATGCAGAAG
ATATCTTAAAGGAGATCAGTATCAACTTCAAAAAACGGAAGGTGCTCAAT
CGCGGTTAAATCAGATTAAAGAGAAAAGTGATCAAGTCCAACATTTTCTA
CCTAATGTGGTTTGAACAAAGTTTTGTCTTTTTATTTTCAAGACAGTTTT
GTAACAATTTTAAAATTTTGGTCAATAGTTGTGATACACCGAAATGTTTA
ACTAGTAAAATAAACACG
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protein sequence of SMED30015973-orf-1

>SMED30015973-orf-1 ID=SMED30015973-orf-1|Name=SMED30015973-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=544bp
MIESSKYEIIWKSLSEPNIITNSDCEYASFLKNLERTCNKTGYLDSKFYT
QQFNSIKSNPSDKKSDTKTAVHPHEIARYRNKFSEDYEKQMKRISRALLE
EKRKERLLKRREGDIVKKEHVLNKSLFEFDSEINSKKFQQDLQLNVTAEE
LEKIQKKFYYDKSKTIKERMRKSVFSHVEKAGKLRQADMNVSKLIREFNA
KKNELDVNAKDISNLMHEFEIQLMREENKHKKLQNELEIYSQALRREIIK
SQTQQEQMQRELQLQQKSKEDEDKVTETSLSLFLNHSDNGIKTAELERKT
LDGQLNKMVNEHSVKICEYGGSLNTIRNKLRECENTQRQLIENANYYNLV
LKNTKNKKKIEEVSSRKLTMANISQSDLIKKRAENEQKYVQLSTNRQILM
DLENAAENADHLKETVRRDKENEKKYFKKMNDSSKDIKQLSTTISRLSKQ
LHDTKVLNSSRINEEKRSADKLEQQMEEELNRLNTQLIELQTKRNNHCNQ
LAECRRYLKGDQYQLQKTEGAQSRLNQIKEKSDQVQHFLPNVV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000106ciliated epithelial cell
PLANA:0000418head
PLANA:0002032epidermal cell
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 212..264
NoneNo IPR availableCOILSCoilCoilcoord: 433..453
NoneNo IPR availableCOILSCoilCoilcoord: 465..503
NoneNo IPR availableCOILSCoilCoilcoord: 398..425
NoneNo IPR availableCOILSCoilCoilcoord: 187..207
NoneNo IPR availableCOILSCoilCoilcoord: 294..314
NoneNo IPR availableCOILSCoilCoilcoord: 87..107
NoneNo IPR availableCOILSCoilCoilcoord: 326..346