Deoxyribonuclease II family protein

Overview
NameDeoxyribonuclease II family protein
Smed IDSMED30015950
Length (bp)2149
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Deoxyribonuclease II family protein (SMED30015950) t-SNE clustered cells

Violin plots show distribution of expression levels for Deoxyribonuclease II family protein (SMED30015950) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Deoxyribonuclease II family protein (SMED30015950) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Deoxyribonuclease II family protein (SMED30015950) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30015950

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30015950h1SMcG0021322 SmedASXL_001138SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
neoblastSMED30015950h1SMcG0021322 dd_Smed_v4_9160_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30015950h1SMcG0021322 dd_Smed_v4_3686_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30015950h1SMcG0021322 dd_Smed_v4_3686_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30015950h1SMcG0021322 dd_Smed_v4_3686_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30015950h1SMcG0021322 dd_Smed_v4_3686_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30015950h1SMcG0021322 dd_Smed_v4_3686_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30015950h1SMcG0021322 dd_Smed_v6_9160_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
zeta neoblastSMED30015950h1SMcG0021322 dd_Smed_v4_9160_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Deoxyribonuclease II family protein vs. Ensembl Human
Match: DNASE2B (deoxyribonuclease 2 beta [Source:HGNC Symbol;Acc:HGNC:28875])

HSP 1 Score: 79.337 bits (194), Expect = 3.456e-15
Identity = 55/179 (30.73%), Postives = 84/179 (46.93%), Query Frame = 1
Query: 1198 GYWLTHSVPNFPM--ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILH-FKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKIHN*IYVFPYHFYAQYSLMQ 1725
            G+WL HS+P FP   E  Y +       GQS +C++ K    + I  QLL+    +YS   P +F    ELI + P+L     S  +   +L   ++      LHFAKS  +  D+++  +A  L   L  ETW+  R  +L S C L Y V  +   K+    Y   Y  +A++ + Q
Sbjct:  138 GFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATF--HQELIHM-PQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKR-QELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQ 312          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Human
Match: DNASE2 (deoxyribonuclease 2, lysosomal [Source:HGNC Symbol;Acc:HGNC:2960])

HSP 1 Score: 54.299 bits (129), Expect = 5.084e-7
Identity = 49/163 (30.06%), Postives = 70/163 (42.94%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELI--SLLPRLIKNIRSKNLVSNILHFK-TLNSMN---LLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +D   G+WL HSVPNFP       Y +  +   YGQ+ +CVS       P  Q   M +   Y+  YP  +   +E I     P L   ++  ++     +   TL S        FAK  K+  DLYS  +A  L  +L V+ W    G  L S C   ++V
Sbjct:  120 LDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSF------PFAQFSKMGKQLTYT--YPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVG-ILPSNCSDIWQV 273          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: nuc-1 (Deoxyribonuclease-2 [Source:UniProtKB/Swiss-Prot;Acc:Q17778])

HSP 1 Score: 100.138 bits (248), Expect = 2.108e-22
Identity = 55/154 (35.71%), Postives = 82/154 (53.25%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 1647
            D ++G WL HSVP FP   +Y +  +   YGQ+ +C++ K   LK I  QL   +  IYSS  PT+   D     L   +    +      +++  +T+   +  +FAKS +++ DLY  L+APTL   L VETWR  RGS++   C+L Y  N
Sbjct:  153 DGTSGVWLVHSVPLFPNPTKYEYPVSGHDYGQTMLCMTFKYAQLKSIGTQLFFNRPNIYSSNLPTNMAADNA--DLAKAIAGQYQKGQPFQSVIELETMAGYSFTNFAKSKEFNADLYDTLVAPTLKTDLVVETWR--RGSEIPLDCKLTYHAN 302          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508])

HSP 1 Score: 90.8929 bits (224), Expect = 2.191e-19
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629
             D  TG+W+ HS+P FP ++ + F      YGQ  +C+S     L  I QQL       Y    P SF N   ++S L     N +S  L S  +  K+L   +  HFAK+ ++ +DLYS  + PTL  S+ VETW +  G +  L S C+
Sbjct:  122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508])

HSP 1 Score: 90.8929 bits (224), Expect = 2.191e-19
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629
             D  TG+W+ HS+P FP ++ + F      YGQ  +C+S     L  I QQL       Y    P SF N   ++S L     N +S  L S  +  K+L   +  HFAK+ ++ +DLYS  + PTL  S+ VETW +  G +  L S C+
Sbjct:  122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508])

HSP 1 Score: 90.8929 bits (224), Expect = 2.272e-19
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629
             D  TG+W+ HS+P FP ++ + F      YGQ  +C+S     L  I QQL       Y    P SF N   ++S L     N +S  L S  +  K+L   +  HFAK+ ++ +DLYS  + PTL  S+ VETW +  G +  L S C+
Sbjct:  122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508])

HSP 1 Score: 90.8929 bits (224), Expect = 2.272e-19
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629
             D  TG+W+ HS+P FP ++ + F      YGQ  +C+S     L  I QQL       Y    P SF N   ++S L     N +S  L S  +  K+L   +  HFAK+ ++ +DLYS  + PTL  S+ VETW +  G +  L S C+
Sbjct:  122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Fly
Match: DNaseII (gene:FBgn0000477 transcript:FBtr0083538)

HSP 1 Score: 90.1225 bits (222), Expect = 5.499e-19
Identity = 53/163 (32.52%), Postives = 86/163 (52.76%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKIHN 1674
            D  T  W+ HSVP FP   +Y +  +   Y QS +CV++K   L+ + Q L+  +   Y    P +  +D    SL   L    R+++     L  ++L+      F KS + + +LY+ ++APTL+ SLFVE WR+G G+ L ++C+   KV  L ++ I N
Sbjct:  126 DGETAIWIVHSVPKFPTIPDYSYPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRNPLATRSDELFPSLERALHGQWRTESPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDVSLFVEAWRDGAGN-LPNSCDKSDKV--LNVESISN 285          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2b (deoxyribonuclease II beta [Source:ZFIN;Acc:ZDB-GENE-090824-2])

HSP 1 Score: 76.6406 bits (187), Expect = 1.431e-14
Identity = 45/156 (28.85%), Postives = 75/156 (48.08%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDM-ELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            D   G+WLTHSVP+FP   E  Y +      YGQ+ +C++   T    I  QL  +   +Y+   P +F  D+ E+  +       I+++  +  +   +++       FAKS  Y  D+Y+  +A  L   L VE+W + +  +L S C L + V
Sbjct:  112 DQDQGFWLTHSVPHFPPFPERNYSYPLTGKYYGQTLLCITFNYTQFPRISWQLAYLNPRVYNCSVPVAFRPDIGEMAQICDGKTPAIKNRRSLQKL---QSVQGQTFFSFAKSQNYVDDIYTGWVAQALGTDLLVESWLH-QAHQLPSNCSLPWHV 263          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2b (deoxyribonuclease II beta [Source:ZFIN;Acc:ZDB-GENE-090824-2])

HSP 1 Score: 76.6406 bits (187), Expect = 1.761e-14
Identity = 45/156 (28.85%), Postives = 75/156 (48.08%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDM-ELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            D   G+WLTHSVP+FP   E  Y +      YGQ+ +C++   T    I  QL  +   +Y+   P +F  D+ E+  +       I+++  +  +   +++       FAKS  Y  D+Y+  +A  L   L VE+W + +  +L S C L + V
Sbjct:  123 DQDQGFWLTHSVPHFPPFPERNYSYPLTGKYYGQTLLCITFNYTQFPRISWQLAYLNPRVYNCSVPVAFRPDIGEMAQICDGKTPAIKNRRSLQKL---QSVQGQTFFSFAKSQNYVDDIYTGWVAQALGTDLLVESWLH-QAHQLPSNCSLPWHV 274          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:ZDB-GENE-010724-16])

HSP 1 Score: 65.855 bits (159), Expect = 6.435e-11
Identity = 49/167 (29.34%), Postives = 76/167 (45.51%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSM---NLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKI 1668
            D   G+WL HS P+FP    E ++ +  +    GQ+F+CV+      + I +QL + Q  I+    P S    +  ++ L +   +       S      +L S+     + FAK   +  DLY   +APTL  +L V+ WR   G  L S C   ++V  L ID I
Sbjct:  120 DKEQGFWLVHSTPHFPPPKSEGQFSYPTSGISNGQNFICVTYPFERFQTIGEQLKINQPHIFDCSIPGSLATAVPAMAQLCKHTLDRWDNTSSSPSNRSISLLSLAKTEFISFAKGASFANDLYHSWVAPTLQSNLLVQFWRRSTGI-LPSDCSPNWEV--LNIDLI 283          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:ZDB-GENE-010724-16])

HSP 1 Score: 65.855 bits (159), Expect = 6.435e-11
Identity = 49/167 (29.34%), Postives = 76/167 (45.51%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSM---NLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKI 1668
            D   G+WL HS P+FP    E ++ +  +    GQ+F+CV+      + I +QL + Q  I+    P S    +  ++ L +   +       S      +L S+     + FAK   +  DLY   +APTL  +L V+ WR   G  L S C   ++V  L ID I
Sbjct:  120 DKEQGFWLVHSTPHFPPPKSEGQFSYPTSGISNGQNFICVTYPFERFQTIGEQLKINQPHIFDCSIPGSLATAVPAMAQLCKHTLDRWDNTSSSPSNRSISLLSLAKTEFISFAKGASFANDLYHSWVAPTLQSNLLVQFWRRSTGI-LPSDCSPNWEV--LNIDLI 283          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Xenopus
Match: dnase2b (deoxyribonuclease II beta [Source:NCBI gene;Acc:496759])

HSP 1 Score: 70.4774 bits (171), Expect = 1.880e-12
Identity = 47/157 (29.94%), Postives = 77/157 (49.04%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELIS--LLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            D+S G+WL HSVP+FP   E+ Y +      +GQ+ +CV+ +    K I  QLL     +Y+   P  +  +M ++    L      I S  L        +      L+FAKS  +  D+++  IA  L  ++ VE+W++ +  +L S C L+Y V
Sbjct:  109 DNSQGFWLIHSVPHFPPYPEDGYGYPSTGKRFGQTAICVTYQYNEFKEIATQLLYYNPNVYNCSVPDIYQKEMWMLHKICLGGHFPWIDSTRLT----QLNSARGEVFLNFAKSKYFIDDIFAAWIAQKLRTNMLVESWQSRQ--QLSSNCSLQYHV 259          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Xenopus
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:NCBI gene;Acc:733868])

HSP 1 Score: 70.8626 bits (172), Expect = 2.052e-12
Identity = 49/163 (30.06%), Postives = 73/163 (44.79%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIY--GQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV-NILFID 1662
            +D   G+WL HS P FP   +  ++   S +  GQSF+CV+        I QQLL      Y S  P  F+ D   +       K   ++   +  +   ++       F+K   +  DLYS  ++  L   LFV+ W+N RG  L S C L +   NI+ ID
Sbjct:  119 LDKKQGFWLVHSTPRFPPPADQSYDWPLSAHRNGQSFLCVTYPYKQFGDIGQQLLYNTILPYDSSIPEDFSVDFPELKTAAE--KGAVTQPPWNRQVVLTSVGGKQFTSFSKHAHFSDDLYSGWVSQVLKSHLFVQFWQNSRGV-LPSNCSLPFHTYNIMEID 278          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2b (deoxyribonuclease II beta [Source:MGI Symbol;Acc:MGI:1913283])

HSP 1 Score: 89.3521 bits (220), Expect = 9.885e-19
Identity = 52/154 (33.77%), Postives = 83/154 (53.90%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNL-VSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            + + G+WL HSVP FP  + Y +  +   YGQ+ +C++   +  + I  QLL++Q  IYS F P++F    +LI  +PR+  N  S  + V  +    +   +N +HFAKS  Y  D+++  IA  L   L  +TW+  +  +L S C L Y V
Sbjct:  129 NRTQGFWLIHSVPKFPPVHGYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTF--HWKLI-YMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQK-KKQELPSNCSLPYHV 278          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2b (deoxyribonuclease II beta [Source:MGI Symbol;Acc:MGI:1913283])

HSP 1 Score: 89.3521 bits (220), Expect = 9.885e-19
Identity = 52/154 (33.77%), Postives = 83/154 (53.90%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNL-VSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            + + G+WL HSVP FP  + Y +  +   YGQ+ +C++   +  + I  QLL++Q  IYS F P++F    +LI  +PR+  N  S  + V  +    +   +N +HFAKS  Y  D+++  IA  L   L  +TW+  +  +L S C L Y V
Sbjct:  129 NRTQGFWLIHSVPKFPPVHGYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTF--HWKLI-YMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQK-KKQELPSNCSLPYHV 278          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2a (deoxyribonuclease II alpha [Source:MGI Symbol;Acc:MGI:1329019])

HSP 1 Score: 62.3882 bits (150), Expect = 6.559e-10
Identity = 48/164 (29.27%), Postives = 75/164 (45.73%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDME--LISLLPRLIKNIRSKNLV-----SNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +D   G+WL HSVP FP       Y +      +GQ+ +CVS+  T    I +QL           YP  + + +E      LP L   I++++++     S+++   +        FAK  K+  DLYS  +A  L  +L V+ W+N  G  L S C   Y+V
Sbjct:  101 LDQEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYT--------YPLVYDHKLEGFFAQKLPDLETVIKNQHVLHEPWNSSVI-LTSQAGATFQSFAKFGKFGDDLYSGWLAEALGTNLQVQFWQNSPG-ILPSNCSGAYQV 254          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2a (deoxyribonuclease II alpha [Source:MGI Symbol;Acc:MGI:1329019])

HSP 1 Score: 62.3882 bits (150), Expect = 6.832e-10
Identity = 48/164 (29.27%), Postives = 75/164 (45.73%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDME--LISLLPRLIKNIRSKNLV-----SNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +D   G+WL HSVP FP       Y +      +GQ+ +CVS+  T    I +QL           YP  + + +E      LP L   I++++++     S+++   +        FAK  K+  DLYS  +A  L  +L V+ W+N  G  L S C   Y+V
Sbjct:  122 LDQEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYT--------YPLVYDHKLEGFFAQKLPDLETVIKNQHVLHEPWNSSVI-LTSQAGATFQSFAKFGKFGDDLYSGWLAEALGTNLQVQFWQNSPG-ILPSNCSGAYQV 275          
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|Q17778|NUC1_CAEEL (Deoxyribonuclease-2 OS=Caenorhabditis elegans OX=6239 GN=nuc-1 PE=3 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 2.682e-21
Identity = 55/154 (35.71%), Postives = 82/154 (53.25%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 1647
            D ++G WL HSVP FP   +Y +  +   YGQ+ +C++ K   LK I  QL   +  IYSS  PT+   D     L   +    +      +++  +T+   +  +FAKS +++ DLY  L+APTL   L VETWR  RGS++   C+L Y  N
Sbjct:  153 DGTSGVWLVHSVPLFPNPTKYEYPVSGHDYGQTMLCMTFKYAQLKSIGTQLFFNRPNIYSSNLPTNMAADNA--DLAKAIAGQYQKGQPFQSVIELETMAGYSFTNFAKSKEFNADLYDTLVAPTLKTDLVVETWR--RGSEIPLDCKLTYHAN 302          
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|P34508|CRN6_CAEEL (Cell death-related nuclease 6 OS=Caenorhabditis elegans OX=6239 GN=crn-6 PE=2 SV=3)

HSP 1 Score: 90.8929 bits (224), Expect = 2.787e-18
Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629
             D  TG+W+ HS+P FP ++ + F      YGQ  +C+S     L  I QQL       Y    P SF N   ++S L     N +S  L S  +  K+L   +  HFAK+ ++ +DLYS  + PTL  S+ VETW +  G +  L S C+
Sbjct:  122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270          
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|Q9QY48|DNS2B_MOUSE (Deoxyribonuclease-2-beta OS=Mus musculus OX=10090 GN=Dnase2b PE=2 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 6.915e-18
Identity = 52/154 (33.77%), Postives = 83/154 (53.90%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNL-VSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            + + G+WL HSVP FP  + Y +  +   YGQ+ +C++   +  + I  QLL++Q  IYS F P++F    +LI  +PR+  N  S  + V  +    +   +N +HFAKS  Y  D+++  IA  L   L  +TW+  +  +L S C L Y V
Sbjct:  129 NRTQGFWLIHSVPKFPPVHGYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTF--HWKLI-YMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQK-KKQELPSNCSLPYHV 278          
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|Q9QZK9|DNS2B_RAT (Deoxyribonuclease-2-beta OS=Rattus norvegicus OX=10116 GN=Dnase2b PE=1 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 2.156e-17
Identity = 54/151 (35.76%), Postives = 78/151 (51.66%), Query Frame = 1
Query: 1198 GYWLTHSVPNFPM--ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            G+WL HS+P FP   E  Y +  +   Y QS +C+++K +  + I  QLL+ Q  IYS F P  F    ELI +     K+  SK     +   ++   +N LHFAKS  Y  D+++  IA  L   L VE+W+  +  +L S C L Y V
Sbjct:  133 GFWLIHSIPKFPPVPEKGYEYPSSGRQYAQSGLCITLKYSQYETIDSQLLVFQPNIYSCFIPNIFR--WELIHMPQMCAKSSASKIPSRRLTVLQSAQGLNFLHFAKSTFYTDDIFAAWIAQKLKVHLLVESWQR-KNHELPSNCSLPYHV 280          
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|P34387|TG198_CAEEL (Cell-death-related nuclease 7 OS=Caenorhabditis elegans OX=6239 GN=crn-7 PE=2 SV=2)

HSP 1 Score: 84.3445 bits (207), Expect = 4.391e-16
Identity = 50/154 (32.47%), Postives = 79/154 (51.30%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSK-NLVSNILHF------KTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSAC 1626
            D +TG+WL HSVPNFP    + +      YGQSF C S++  +L  + +    +QAT Y    P  +       +  P L KN+ +K +L  +   F      KT+  + L+ +AK  K+D D+++ LI+     +L VE+W NG G  + + C
Sbjct:  117 DSTTGFWLIHSVPNFPPIKSFSYPNTAEKYGQSFFCASMEVQHLTELAEHWKYIQATPYIINIPEKYA------TRFPTL-KNVEAKQSLPRSATQFWISKPIKTVQGVTLMAYAKHKKFDGDIWNDLISRQNKVTLAVESWLNGSGDDIHTTC 263          
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A1S0TKK1 (Deoxyribonuclease II family protein OS=Loa loa OX=7209 GN=LOAG_13388 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 3.181e-25
Identity = 63/153 (41.18%), Postives = 89/153 (58.17%), Query Frame = 1
Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRL-IKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            D++G+WL HSVP FP    YF+ +   IYGQSFMCV++K T ++   + +  +   +Y    P +F      ++ L +L  KNI + +L+ N   FK+ + M   +FAKS KY +DLYS +IA  +  SLF ETW NG    LDS C   YKV
Sbjct:  110 DTSGFWLIHSVPKFPSLKHYFYAQNGEIYGQSFMCVTLKTTSIEIFAEAMKYIYPAVYGMNVPKTFLARFPFLNDLKQLKKKNIANTSLMKN---FKSNDGMIFYNFAKSDKYKKDLYSDMIARQMKVSLFTETWMNGGAKDLDSDCSTAYKV 259          
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A1I7VP13 (Deoxyribonuclease II family protein OS=Loa loa OX=7209 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 5.859e-25
Identity = 63/153 (41.18%), Postives = 89/153 (58.17%), Query Frame = 1
Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRL-IKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            D++G+WL HSVP FP    YF+ +   IYGQSFMCV++K T ++   + +  +   +Y    P +F      ++ L +L  KNI + +L+ N   FK+ + M   +FAKS KY +DLYS +IA  +  SLF ETW NG    LDS C   YKV
Sbjct:  122 DTSGFWLIHSVPKFPSLKHYFYAQNGEIYGQSFMCVTLKTTSIEIFAEAMKYIYPAVYGMNVPKTFLARFPFLNDLKQLKKKNIANTSLMKN---FKSNDGMIFYNFAKSDKYKKDLYSDMIARQMKVSLFTETWMNGGAKDLDSDCSTAYKV 271          
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A3P7EJU9 (Uncharacterized protein OS=Wuchereria bancrofti OX=6293 GN=WBA_LOCUS11946 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.761e-24
Identity = 61/152 (40.13%), Postives = 86/152 (56.58%), Query Frame = 1
Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +++G+WL HSVP FP    Y + +    YGQSF+CV++K T +K  V  +  +   +Y    P +F N    +  L  L K  R  N+ S +  FK+  SM+   F+K+ KY++DLY  LIA  +N SLF ETW NG    L+S C  KYKV
Sbjct:  125 NTSGFWLVHSVPKFPSLKRYSYTENGQTYGQSFLCVTLKMTSIKVFVNAMRYIYPEVYGINVPRNFLNTFPFLEDLKELKKK-RISNMSSLVQSFKSNGSMDFFDFSKTGKYNKDLYLDLIAKEMNVSLFAETWMNGAAKDLNSECTTKYKV 275          
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A4E9F0C8 (Uncharacterized protein OS=Brugia malayi OX=6279 GN=Bma-crn-7.2 PE=4 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 4.092e-24
Identity = 59/152 (38.82%), Postives = 87/152 (57.24%), Query Frame = 1
Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +++G+WL HSVP FP    Y + +    YGQSF+CV++K T +K     +  +   +Y    P +F N   L+  L  L K  R  N+ S + +FK+  +++   F+K+ KY++DLY  LIA  +N SLF ETW NG    L+S C  KYKV
Sbjct:   67 NTSGFWLVHSVPKFPSLKRYSYAENGQTYGQSFLCVTLKTTSIKVFANAMRYIYPEVYGITVPRNFLNRFPLLEDLKELKKK-RISNMSSLLQNFKSNGNVDFFAFSKTGKYNKDLYLDLIAKEMNVSLFAETWMNGAAKDLNSECTTKYKV 217          
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A4E9EVB0 (Uncharacterized protein OS=Brugia malayi OX=6279 GN=Bma-crn-7.3 PE=4 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.291e-23
Identity = 59/152 (38.82%), Postives = 87/152 (57.24%), Query Frame = 1
Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +++G+WL HSVP FP    Y + +    YGQSF+CV++K T +K     +  +   +Y    P +F N   L+  L  L K  R  N+ S + +FK+  +++   F+K+ KY++DLY  LIA  +N SLF ETW NG    L+S C  KYKV
Sbjct:  110 NTSGFWLVHSVPKFPSLKRYSYAENGQTYGQSFLCVTLKTTSIKVFANAMRYIYPEVYGITVPRNFLNRFPLLEDLKELKKK-RISNMSSLLQNFKSNGNVDFFAFSKTGKYNKDLYLDLIAKEMNVSLFAETWMNGAAKDLNSECTTKYKV 260          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Cavefish
Match: dnase2 (deoxyribonuclease-2-alpha-like [Source:NCBI gene;Acc:103028211])

HSP 1 Score: 79.7221 bits (195), Expect = 1.393e-15
Identity = 48/164 (29.27%), Postives = 79/164 (48.17%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIR--------SKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            DD  G+WL HS P+FP    E ++ + ++ +  GQ+F+CV+      + I +QL + Q  +Y    P S  + +  +  L +  ++ R        S +  +  +   +L     + FAK   +D DLY   +AP L   L V+ WR   G  L+S C+  YKV
Sbjct:  121 DDKQGFWLVHSTPHFPPLKTEGKFSYPESGTQNGQNFICVTYPLDRFETIGEQLKINQPHVYDCHIPESLASSVPSMVNLCKENQHRRNSSNAPPPSYSSANRSVSLLSLGGKEFISFAKGAAFDNDLYHSWVAPALQADLLVQFWRRSTGI-LESDCDPSYKV 283          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Cavefish
Match: dnase2b (deoxyribonuclease 2 beta [Source:NCBI gene;Acc:103030372])

HSP 1 Score: 78.9518 bits (193), Expect = 2.492e-15
Identity = 50/169 (29.59%), Postives = 82/169 (48.52%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLL-----PRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKIH 1671
            D S G+W+THS+P+FP  +E  + +     +YGQ+  C +      K I QQL  +   +Y+   P  +  DM  ++ L     P +    + + L S +           L F+KS +Y  D+Y+  +A TL   L VE+W+     +L S C L Y  ++L I ++H
Sbjct:  140 DRSQGFWITHSIPHFPPFLEMGFGYPSTGKLYGQTVHCTTYSYEQFKKISQQLAYINPRVYNCSVPVPYHTDMAAMAQLCGGKRPTVAPRRKLEKLKSAL-------GETFLSFSKSHQYVDDIYAGWVAQTLRTDLLVESWQRDN-HQLPSNCSLPY--HVLNIKRVH 298          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Sea Lamprey
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:ZDB-GENE-010724-16])

HSP 1 Score: 68.5514 bits (166), Expect = 1.096e-12
Identity = 46/160 (28.75%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDM-ELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQ---DLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +D + G+WL HS P+FP  +   + +      YGQSF+CVS        I  QL   +   YS        + + +L +L  +    + S    + ++   +        FAK+ ++D    DLY  L+AP L  SL++E+W +G G   DS C  ++ V
Sbjct:   95 LDGTGGFWLVHSTPHFPPSVPGPFAWPHTALRYGQSFLCVSYGFDQFGDIALQLRYNEPDHYSCQVGAQLKDKLPDLQALCAKTKLQVES---ATRVVELTSSAGKTFRSFAKTHRFDDGASDLYVHLVAPNLKSSLYLESWVHGVGV-FDSNCSGEFCV 250          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Match: dnase2 (deoxyribonuclease 2, lysosomal [Source:NCBI gene;Acc:101162954])

HSP 1 Score: 86.6557 bits (213), Expect = 9.300e-18
Identity = 49/160 (30.63%), Postives = 80/160 (50.00%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPME---NEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLL---PRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            +D + G+WL HS P+FP E    EY++  +    GQ+F+CV+      + I +QL + Q  +Y    P S  + +  ++ L    RL   + S+ + +  +   +++  N + FAK   +D DLY   +AP L   L V+ W    G  L S C L +KV
Sbjct:  124 LDQNQGFWLVHSTPHFPPERQAGEYYYPSSGVNNGQNFLCVTYPLKSFQTIGEQLQINQPHVYDCDIPESMVSLVPALAALCKKARLSDEVSSRPMSNRSMTLTSMDGTNFISFAKGASFDDDLYHGWVAPALQSDLLVQFWIRSTG-ILPSDCSLGWKV 282          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Match: dnase2b (deoxyribonuclease-2-beta [Source:NCBI gene;Acc:101174093])

HSP 1 Score: 70.4774 bits (171), Expect = 1.479e-12
Identity = 45/163 (27.61%), Postives = 79/163 (48.47%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPM--ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLL-----PRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACEL-KYKVNI 1650
            D + G+WL+HS+P+FP   E  Y +  +  + GQ+ +C++ +      I QQL  +    Y+   P + + D+  ++ L     P L  +   + L SN            + F KS  +  D+Y+  +A  L+  L VE+W+  +G  L S C L ++ +NI
Sbjct:  127 DHAKGFWLSHSIPHFPSFPERGYLYPSSGKLNGQTLLCMTYQYAQFLKIAQQLEYLYPRFYNCSVPAALSADLPQLAKLCAGSKPALASDKSMQPLFSN-------RGEKFISFVKSDHFVDDIYTGWVAQVLDTDLLVESWQT-QGRVLPSNCSLPRHAMNI 281          
BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Match: ENSORLT00000036979.1 (deoxyribonuclease-2-alpha [Source:NCBI gene;Acc:101173852])

HSP 1 Score: 69.707 bits (169), Expect = 2.670e-12
Identity = 42/140 (30.00%), Postives = 71/140 (50.71%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPM-ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELI---SLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETW 1590
            +D  TG WL+HS P FP   ++ F+ ++ +   Q+FMC++      + I  QL  + A  + S  P  F  +++ +   S  P+     +  NL       K++   + L FAK  ++  DLYS LI  TL  +L+V++W
Sbjct:  122 LDRQTGVWLSHSTPRFPTYRSQNFWPESGNANAQAFMCITFPYAQFEAIGLQLKYIHAYSFDSHVPQVFHMELQCVAQRSCYPKKEPWFKVANL-------KSMGGHSFLSFAKYTRFKDDLYSGLITNTLPSNLYVKSW 254          
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000062594.1 (SMESG000062594.1)

HSP 1 Score: 323.168 bits (827), Expect = 1.431e-104
Identity = 155/156 (99.36%), Postives = 156/156 (100.00%), Query Frame = 1
Query: 1180 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 1647
            NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQAT+YSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN
Sbjct:  115 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATVYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 270          

HSP 2 Score: 160.999 bits (406), Expect = 1.381e-43
Identity = 75/77 (97.40%), Postives = 77/77 (100.00%), Query Frame = 2
Query:  197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKGV 427
            FVAIKHPKSYNFVYLSSANADSHWKESNYDL+SEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKG+
Sbjct:   37 FVAIKHPKSYNFVYLSSANADSHWKESNYDLKSEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKGI 113          
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000081036.1 (SMESG000081036.1)

HSP 1 Score: 156.377 bits (394), Expect = 3.394e-42
Identity = 77/155 (49.68%), Postives = 103/155 (66.45%), Query Frame = 1
Query: 1180 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            N D+ TGYWL HSVP+FP    Y +   Q I GQSF+CVSIK + L  +V+QLL+M A +YS ++P SFT +  L   L RL+ N+ S ++ SN++H  T++ + L+HF KS  +  DLYS LIAP L  SLFVE+W NG G +  S C+L YKV
Sbjct:   93 NFDEETGYWLIHSVPHFPPVRGYSYPDPQHINGQSFICVSIKTSDLNDVVKQLLLMYARVYSYYFPRSFTANTTLDYNLGRLVHNMHSPSIKSNVIHLNTISKVPLIHFGKSKLFANDLYSVLIAPQLKESLFVESWLNGNGGREPSNCQLTYKV 247          

HSP 2 Score: 75.8702 bits (185), Expect = 1.244e-14
Identity = 40/79 (50.63%), Postives = 52/79 (65.82%), Query Frame = 2
Query:  197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNT--KCFYIYYNDDRPLSNSSTKGGHLKGV 427
            ++AIK+P  YNF YLSS    + WK  NY L S+KNL+A+TL Q+Y   N   K FY +YNDD+  + S +  GHLKGV
Sbjct:   13 YIAIKYPGVYNFFYLSSETNGNTWKLPNYALNSDKNLVALTLSQAYSAENNKDKTFYAFYNDDKSKNVSGSNDGHLKGV 91          
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000081036.1 (SMESG000081036.1)

HSP 1 Score: 156.377 bits (394), Expect = 5.122e-42
Identity = 77/155 (49.68%), Postives = 103/155 (66.45%), Query Frame = 1
Query: 1180 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            N D+ TGYWL HSVP+FP    Y +   Q I GQSF+CVSIK + L  +V+QLL+M A +YS ++P SFT +  L   L RL+ N+ S ++ SN++H  T++ + L+HF KS  +  DLYS LIAP L  SLFVE+W NG G +  S C+L YKV
Sbjct:  115 NFDEETGYWLIHSVPHFPPVRGYSYPDPQHINGQSFICVSIKTSDLNDVVKQLLLMYARVYSYYFPRSFTANTTLDYNLGRLVHNMHSPSIKSNVIHLNTISKVPLIHFGKSKLFANDLYSVLIAPQLKESLFVESWLNGNGGREPSNCQLTYKV 269          

HSP 2 Score: 75.8702 bits (185), Expect = 1.491e-14
Identity = 40/79 (50.63%), Postives = 52/79 (65.82%), Query Frame = 2
Query:  197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNT--KCFYIYYNDDRPLSNSSTKGGHLKGV 427
            ++AIK+P  YNF YLSS    + WK  NY L S+KNL+A+TL Q+Y   N   K FY +YNDD+  + S +  GHLKGV
Sbjct:   35 YIAIKYPGVYNFFYLSSETNGNTWKLPNYALNSDKNLVALTLSQAYSAENNKDKTFYAFYNDDKSKNVSGSNDGHLKGV 113          
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000062993.1 (SMESG000062993.1)

HSP 1 Score: 131.339 bits (329), Expect = 4.067e-33
Identity = 72/154 (46.75%), Postives = 98/154 (63.64%), Query Frame = 1
Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNI-LHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644
            D + G+WL HSVP FP    Y + KA+ IYGQSF+CVS+++  L+ IV QLL+MQ+T+YS   P +F  + +L +LL   I N   K   +N+ +  KTL S+ L+HF KS  + QDLYS L+AP L  S+ VE+W   RG K+DS C   Y V
Sbjct:  111 DINNGFWLIHSVPLFPTFGNYTYGKAEEIYGQSFICVSLESENLQNIVIQLLLMQSTVYSYNLPENFPVNDKLKTLLTNFINNKNMKIQQTNMTIIMKTLKSLPLVHFGKSYSFGQDLYSGLVAPGLQASIMVESWI--RGEKVDSTCGTDYHV 262          

HSP 2 Score: 68.5514 bits (166), Expect = 3.958e-12
Identity = 38/90 (42.22%), Postives = 54/90 (60.00%), Query Frame = 2
Query:  197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKGVKFIKN*NHFLSLH 466
            F+ +K PKSY FVY+SS +    W  S +DL S+ N+I  T++Q+Y    ++ FY YYND+ P    S++ GHLKGV      N F  +H
Sbjct:   34 FIGLKFPKSYKFVYISSQSET--WTTSKFDLSSKNNMIGWTIEQTYSSHQSQSFYAYYNDETPKFTYSSR-GHLKGVISFDINNGFWLIH 120          
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000081051.1 (SMESG000081051.1)

HSP 1 Score: 101.679 bits (252), Expect = 5.592e-24
Identity = 49/116 (42.24%), Postives = 70/116 (60.34%), Query Frame = 1
Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQ 1530
             D S GYWL HSVP FP  NEY +   Q  +GQSF+CVS+K   L  +V QLL+M   +YS F P  F+ +  L+  +  L+ N   K+  SN+ +F T+ + NL+HF KS  +++
Sbjct:  115 FDKSEGYWLVHSVPKFPFPNEYKYGSGQLKFGQSFICVSLKFQNLNSLVDQLLIMTTNVYSYFVPEGFSQNSSLMDKINSLVNNSIKKSKDSNVFNFNTVKNFNLIHFGKSRLFNR 230          
The following BLAST results are available for this feature:
BLAST of Deoxyribonuclease II family protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
DNASE2B3.456e-1530.73deoxyribonuclease 2 beta [Source:HGNC Symbol;Acc:H... [more]
DNASE25.084e-730.06deoxyribonuclease 2, lysosomal [Source:HGNC Symbol... [more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nuc-12.108e-2235.71Deoxyribonuclease-2 [Source:UniProtKB/Swiss-Prot;... [more]
crn-62.191e-1935.10Cell death-related nuclease 6 [Source:UniProtKB/S... [more]
crn-62.191e-1935.10Cell death-related nuclease 6 [Source:UniProtKB/S... [more]
crn-62.272e-1935.10Cell death-related nuclease 6 [Source:UniProtKB/S... [more]
crn-62.272e-1935.10Cell death-related nuclease 6 [Source:UniProtKB/S... [more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
DNaseII5.499e-1932.52gene:FBgn0000477 transcript:FBtr0083538[more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dnase2b1.431e-1428.85deoxyribonuclease II beta [Source:ZFIN;Acc:ZDB-GEN... [more]
dnase2b1.761e-1428.85deoxyribonuclease II beta [Source:ZFIN;Acc:ZDB-GEN... [more]
dnase26.435e-1129.34deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:Z... [more]
dnase26.435e-1129.34deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:Z... [more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dnase2b1.880e-1229.94deoxyribonuclease II beta [Source:NCBI gene;Acc:49... [more]
dnase22.052e-1230.06deoxyribonuclease II, lysosomal [Source:NCBI gene;... [more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Dnase2b9.885e-1933.77deoxyribonuclease II beta [Source:MGI Symbol;Acc:M... [more]
Dnase2b9.885e-1933.77deoxyribonuclease II beta [Source:MGI Symbol;Acc:M... [more]
Dnase2a6.559e-1029.27deoxyribonuclease II alpha [Source:MGI Symbol;Acc:... [more]
Dnase2a6.832e-1029.27deoxyribonuclease II alpha [Source:MGI Symbol;Acc:... [more]
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BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q17778|NUC1_CAEEL2.682e-2135.71Deoxyribonuclease-2 OS=Caenorhabditis elegans OX=6... [more]
sp|P34508|CRN6_CAEEL2.787e-1835.10Cell death-related nuclease 6 OS=Caenorhabditis el... [more]
sp|Q9QY48|DNS2B_MOUSE6.915e-1833.77Deoxyribonuclease-2-beta OS=Mus musculus OX=10090 ... [more]
sp|Q9QZK9|DNS2B_RAT2.156e-1735.76Deoxyribonuclease-2-beta OS=Rattus norvegicus OX=1... [more]
sp|P34387|TG198_CAEEL4.391e-1632.47Cell-death-related nuclease 7 OS=Caenorhabditis el... [more]
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BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S0TKK13.181e-2541.18Deoxyribonuclease II family protein OS=Loa loa OX=... [more]
A0A1I7VP135.859e-2541.18Deoxyribonuclease II family protein OS=Loa loa OX=... [more]
A0A3P7EJU92.761e-2440.13Uncharacterized protein OS=Wuchereria bancrofti OX... [more]
A0A4E9F0C84.092e-2438.82Uncharacterized protein OS=Brugia malayi OX=6279 G... [more]
A0A4E9EVB01.291e-2338.82Uncharacterized protein OS=Brugia malayi OX=6279 G... [more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dnase21.393e-1529.27deoxyribonuclease-2-alpha-like [Source:NCBI gene;A... [more]
dnase2b2.492e-1529.59deoxyribonuclease 2 beta [Source:NCBI gene;Acc:103... [more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
dnase21.096e-1228.75deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:Z... [more]
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dnase29.300e-1830.63deoxyribonuclease 2, lysosomal [Source:NCBI gene;A... [more]
dnase2b1.479e-1227.61deoxyribonuclease-2-beta [Source:NCBI gene;Acc:101... [more]
ENSORLT00000036979.12.670e-1230.00deoxyribonuclease-2-alpha [Source:NCBI gene;Acc:10... [more]
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BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000062594.11.431e-10499.36SMESG000062594.1[more]
SMESG000081036.13.394e-4249.68SMESG000081036.1[more]
SMESG000081036.15.122e-4249.68SMESG000081036.1[more]
SMESG000062993.14.067e-3346.75SMESG000062993.1[more]
SMESG000081051.15.592e-2442.24SMESG000081051.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015950 ID=SMED30015950|Name=Deoxyribonuclease II family protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2149bp
AAATTTTAAATCCAAGAACTTACAAAGACTCCGGATAATATTGTAATGCT
GTTTCGATATATTTATTTGTTTAGTAATAAATGTGTATACAAGTCATCAA
TATTTCGCGGGGTTTAATAATATCGACATTTTCTCCGCAAATGAAGTTTA
ATTAGGATCCATATTTCAATAAGGATGGATTATAAAAGTTATCAGGTTTG
TCGCGATTAAACATCCAAAATCATATAATTTCGTATATTTGTCGTCAGCG
AATGCAGATTCGCACTGGAAAGAATCTAATTACGACCTAAGAAGCGAGAA
AAATTTGATAGCCATCACTCTTCAGCAGAGCTATCTGCATTGCAATACGA
AATGTTTTTATATTTATTACAATGATGACAGGCCTCTTAGTAATTCTTCG
ACGAAAGGAGGGCATTTGAAAGGTGTAAAATTTATTAAAAACTAAAATCA
TTTTTTATCATTACATCACCATATTAAATAAAACTTATGGGTTGTTGAAT
TCAGATCCTAAAATAATTTCTTCTGTCAACACGAATCTTAAACAATGTTA
TTCAAAGAGCAAAACGTATCAGTTGCTGTTATACACAAAGACATTAGTCA
CAAACATCTACGCAAAAAACTAATTCTTTATTAACGGTTATCAAATCTAA
TGAAAAAATGAACCAGACAGCTTGATTTGGTGTTAATTTTTGATTTATTT
CCCATGGGGAGGGTGTAAAAGCTATTATCTCTTTGGTTTTTATATATTTA
TCAATTTCATATTTCTCTAAAATAAACTTAATCGAACCCTTCATGGATCT
CTGGAGTACTTTACGCGAATTTTCATAACTTTCCTTTAAATGAAACCTTT
ACGCTAGTCTCATCATCAACACTTTGATTTGCGCCGCTTAACAAGCTTTT
GGAACAATTAGCTGGTGTGATTGGGTTGCTAAAATTTTCTAGTATCATAT
CATCCCAATGGCGTTTTCACAGATAGCTACCTGCTACATGCTTCAATGGA
TCAAAATAATCAAAAAATGTTGAGAAAAAAGTTCCACACTAAATGAAATC
ATATAAACATTTTTCCGGTTTTCATATCGTACACAAGAAATTTAATTTAT
AAAGTTTTTTTCTGGAAATCTCGCAACAATTATTATTGCTGGTTTATATA
TTATTTTAATTTGTTATTAAGGTATACTAAATATGGATGACTCTACTGGT
TATTGGCTGACGCATTCTGTGCCGAATTTCCCAATGGAAAACGAGTATTT
TTTTAATAAAGCTCAATCTATTTACGGGCAAAGTTTTATGTGCGTTTCAA
TAAAAAATACCTACCTCAAACCAATTGTACAGCAATTATTGATGATGCAA
GCCACCATATACAGCAGCTTTTATCCAACTTCATTCACTAATGACATGGA
ATTAATTTCTCTTCTTCCACGTCTTATCAAGAACATTCGATCCAAGAATC
TTGTTTCAAATATTCTTCATTTCAAAACGCTTAATTCGATGAACTTGCTA
CACTTCGCAAAATCACCAAAATATGATCAAGATTTGTATTCGAAATTAAT
TGCACCAACTTTAAATGGCTCCCTTTTTGTCGAAACTTGGAGAAATGGAA
GAGGAAGTAAATTAGATTCTGCATGTGAATTAAAATACAAAGTAAATATA
TTATTTATAGACAAAATTCATAATTAAATATACGTTTTTCCTTATCATTT
TTACGCTCAGTACAGCCTTATGCAGATATGAGCTTGCTTATCCACCTTCA
CCTGGGATGGAGTATATGTCTTATGAATCTGTCTTACGATTTCTTGCTTG
CACCGAAAACTTTAGAATATTAATTTTTAAGTACAGAATTATGCATAATT
GTGCAAAAGCTGACTATAGTCAAAATTACTTTGAAAATTTCTTTTTGCAA
AATTATTCTACTTAATGAGACGAGTCATTTATTTGGCAACTACTTTAAAG
AATTTTTATCGGAAGATGTCAAAAGTATGAACAAGAATTTGTCTCACTTT
AGTGCAAAGAACTTGATGTTTTTCTAGATTTGCCTTTGGAAAATAACAGA
GTTTGCCAATATGGTTTTTTGCTGACGTAGACCTTTTAATATCCCTTTTA
GATAACAGTTAAAATGTATGATTGATTTAAATTAAAACTATTATGTGAT
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protein sequence of SMED30015950-orf-1

>SMED30015950-orf-1 ID=SMED30015950-orf-1|Name=SMED30015950-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=165bp
MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQ
QLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTL
NSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACEL
KYKVNILFIDKIHN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000420parapharyngeal region
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR004947DNase_II
Vocabulary: molecular function
TermDefinition
GO:0004531deoxyribonuclease II activity
Vocabulary: biological process
TermDefinition
GO:0006259DNA metabolic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004947Deoxyribonuclease IIPFAMPF03265DNase_IIcoord: 2..155
e-value: 2.4E-36
score: 125.7
IPR004947Deoxyribonuclease IIPANTHERPTHR10858DEOXYRIBONUCLEASE IIcoord: 2..155
NoneNo IPR availablePANTHERPTHR10858:SF23DEOXYRIBONUCLEASE IIcoord: 2..155