Deoxyribonuclease II family protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015950 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Deoxyribonuclease II family protein vs. Ensembl Human
Match: DNASE2B (deoxyribonuclease 2 beta [Source:HGNC Symbol;Acc:HGNC:28875]) HSP 1 Score: 79.337 bits (194), Expect = 3.456e-15 Identity = 55/179 (30.73%), Postives = 84/179 (46.93%), Query Frame = 1 Query: 1198 GYWLTHSVPNFPM--ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILH-FKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKIHN*IYVFPYHFYAQYSLMQ 1725 G+WL HS+P FP E Y + GQS +C++ K + I QLL+ +YS P +F ELI + P+L S + +L ++ LHFAKS + D+++ +A L L ETW+ R +L S C L Y V + K+ Y Y +A++ + Q Sbjct: 138 GFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATF--HQELIHM-PQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKR-QELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQ 312
BLAST of Deoxyribonuclease II family protein vs. Ensembl Human
Match: DNASE2 (deoxyribonuclease 2, lysosomal [Source:HGNC Symbol;Acc:HGNC:2960]) HSP 1 Score: 54.299 bits (129), Expect = 5.084e-7 Identity = 49/163 (30.06%), Postives = 70/163 (42.94%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELI--SLLPRLIKNIRSKNLVSNILHFK-TLNSMN---LLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +D G+WL HSVPNFP Y + + YGQ+ +CVS P Q M + Y+ YP + +E I P L ++ ++ + TL S FAK K+ DLYS +A L +L V+ W G L S C ++V Sbjct: 120 LDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSF------PFAQFSKMGKQLTYT--YPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVG-ILPSNCSDIWQV 273
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: nuc-1 (Deoxyribonuclease-2 [Source:UniProtKB/Swiss-Prot;Acc:Q17778]) HSP 1 Score: 100.138 bits (248), Expect = 2.108e-22 Identity = 55/154 (35.71%), Postives = 82/154 (53.25%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 1647 D ++G WL HSVP FP +Y + + YGQ+ +C++ K LK I QL + IYSS PT+ D L + + +++ +T+ + +FAKS +++ DLY L+APTL L VETWR RGS++ C+L Y N Sbjct: 153 DGTSGVWLVHSVPLFPNPTKYEYPVSGHDYGQTMLCMTFKYAQLKSIGTQLFFNRPNIYSSNLPTNMAADNA--DLAKAIAGQYQKGQPFQSVIELETMAGYSFTNFAKSKEFNADLYDTLVAPTLKTDLVVETWR--RGSEIPLDCKLTYHAN 302
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508]) HSP 1 Score: 90.8929 bits (224), Expect = 2.191e-19 Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629 D TG+W+ HS+P FP ++ + F YGQ +C+S L I QQL Y P SF N ++S L N +S L S + K+L + HFAK+ ++ +DLYS + PTL S+ VETW + G + L S C+ Sbjct: 122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508]) HSP 1 Score: 90.8929 bits (224), Expect = 2.191e-19 Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629 D TG+W+ HS+P FP ++ + F YGQ +C+S L I QQL Y P SF N ++S L N +S L S + K+L + HFAK+ ++ +DLYS + PTL S+ VETW + G + L S C+ Sbjct: 122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508]) HSP 1 Score: 90.8929 bits (224), Expect = 2.272e-19 Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629 D TG+W+ HS+P FP ++ + F YGQ +C+S L I QQL Y P SF N ++S L N +S L S + K+L + HFAK+ ++ +DLYS + PTL S+ VETW + G + L S C+ Sbjct: 122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Match: crn-6 (Cell death-related nuclease 6 [Source:UniProtKB/Swiss-Prot;Acc:P34508]) HSP 1 Score: 90.8929 bits (224), Expect = 2.272e-19 Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629 D TG+W+ HS+P FP ++ + F YGQ +C+S L I QQL Y P SF N ++S L N +S L S + K+L + HFAK+ ++ +DLYS + PTL S+ VETW + G + L S C+ Sbjct: 122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270
BLAST of Deoxyribonuclease II family protein vs. Ensembl Fly
Match: DNaseII (gene:FBgn0000477 transcript:FBtr0083538) HSP 1 Score: 90.1225 bits (222), Expect = 5.499e-19 Identity = 53/163 (32.52%), Postives = 86/163 (52.76%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKIHN 1674 D T W+ HSVP FP +Y + + Y QS +CV++K L+ + Q L+ + Y P + +D SL L R+++ L ++L+ F KS + + +LY+ ++APTL+ SLFVE WR+G G+ L ++C+ KV L ++ I N Sbjct: 126 DGETAIWIVHSVPKFPTIPDYSYPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRNPLATRSDELFPSLERALHGQWRTESPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDVSLFVEAWRDGAGN-LPNSCDKSDKV--LNVESISN 285
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2b (deoxyribonuclease II beta [Source:ZFIN;Acc:ZDB-GENE-090824-2]) HSP 1 Score: 76.6406 bits (187), Expect = 1.431e-14 Identity = 45/156 (28.85%), Postives = 75/156 (48.08%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDM-ELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 D G+WLTHSVP+FP E Y + YGQ+ +C++ T I QL + +Y+ P +F D+ E+ + I+++ + + +++ FAKS Y D+Y+ +A L L VE+W + + +L S C L + V Sbjct: 112 DQDQGFWLTHSVPHFPPFPERNYSYPLTGKYYGQTLLCITFNYTQFPRISWQLAYLNPRVYNCSVPVAFRPDIGEMAQICDGKTPAIKNRRSLQKL---QSVQGQTFFSFAKSQNYVDDIYTGWVAQALGTDLLVESWLH-QAHQLPSNCSLPWHV 263
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2b (deoxyribonuclease II beta [Source:ZFIN;Acc:ZDB-GENE-090824-2]) HSP 1 Score: 76.6406 bits (187), Expect = 1.761e-14 Identity = 45/156 (28.85%), Postives = 75/156 (48.08%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDM-ELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 D G+WLTHSVP+FP E Y + YGQ+ +C++ T I QL + +Y+ P +F D+ E+ + I+++ + + +++ FAKS Y D+Y+ +A L L VE+W + + +L S C L + V Sbjct: 123 DQDQGFWLTHSVPHFPPFPERNYSYPLTGKYYGQTLLCITFNYTQFPRISWQLAYLNPRVYNCSVPVAFRPDIGEMAQICDGKTPAIKNRRSLQKL---QSVQGQTFFSFAKSQNYVDDIYTGWVAQALGTDLLVESWLH-QAHQLPSNCSLPWHV 274
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:ZDB-GENE-010724-16]) HSP 1 Score: 65.855 bits (159), Expect = 6.435e-11 Identity = 49/167 (29.34%), Postives = 76/167 (45.51%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSM---NLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKI 1668 D G+WL HS P+FP E ++ + + GQ+F+CV+ + I +QL + Q I+ P S + ++ L + + S +L S+ + FAK + DLY +APTL +L V+ WR G L S C ++V L ID I Sbjct: 120 DKEQGFWLVHSTPHFPPPKSEGQFSYPTSGISNGQNFICVTYPFERFQTIGEQLKINQPHIFDCSIPGSLATAVPAMAQLCKHTLDRWDNTSSSPSNRSISLLSLAKTEFISFAKGASFANDLYHSWVAPTLQSNLLVQFWRRSTGI-LPSDCSPNWEV--LNIDLI 283
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:ZDB-GENE-010724-16]) HSP 1 Score: 65.855 bits (159), Expect = 6.435e-11 Identity = 49/167 (29.34%), Postives = 76/167 (45.51%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSM---NLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKI 1668 D G+WL HS P+FP E ++ + + GQ+F+CV+ + I +QL + Q I+ P S + ++ L + + S +L S+ + FAK + DLY +APTL +L V+ WR G L S C ++V L ID I Sbjct: 120 DKEQGFWLVHSTPHFPPPKSEGQFSYPTSGISNGQNFICVTYPFERFQTIGEQLKINQPHIFDCSIPGSLATAVPAMAQLCKHTLDRWDNTSSSPSNRSISLLSLAKTEFISFAKGASFANDLYHSWVAPTLQSNLLVQFWRRSTGI-LPSDCSPNWEV--LNIDLI 283
BLAST of Deoxyribonuclease II family protein vs. Ensembl Xenopus
Match: dnase2b (deoxyribonuclease II beta [Source:NCBI gene;Acc:496759]) HSP 1 Score: 70.4774 bits (171), Expect = 1.880e-12 Identity = 47/157 (29.94%), Postives = 77/157 (49.04%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELIS--LLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 D+S G+WL HSVP+FP E+ Y + +GQ+ +CV+ + K I QLL +Y+ P + +M ++ L I S L + L+FAKS + D+++ IA L ++ VE+W++ + +L S C L+Y V Sbjct: 109 DNSQGFWLIHSVPHFPPYPEDGYGYPSTGKRFGQTAICVTYQYNEFKEIATQLLYYNPNVYNCSVPDIYQKEMWMLHKICLGGHFPWIDSTRLT----QLNSARGEVFLNFAKSKYFIDDIFAAWIAQKLRTNMLVESWQSRQ--QLSSNCSLQYHV 259
BLAST of Deoxyribonuclease II family protein vs. Ensembl Xenopus
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:NCBI gene;Acc:733868]) HSP 1 Score: 70.8626 bits (172), Expect = 2.052e-12 Identity = 49/163 (30.06%), Postives = 73/163 (44.79%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIY--GQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV-NILFID 1662 +D G+WL HS P FP + ++ S + GQSF+CV+ I QQLL Y S P F+ D + K ++ + + ++ F+K + DLYS ++ L LFV+ W+N RG L S C L + NI+ ID Sbjct: 119 LDKKQGFWLVHSTPRFPPPADQSYDWPLSAHRNGQSFLCVTYPYKQFGDIGQQLLYNTILPYDSSIPEDFSVDFPELKTAAE--KGAVTQPPWNRQVVLTSVGGKQFTSFSKHAHFSDDLYSGWVSQVLKSHLFVQFWQNSRGV-LPSNCSLPFHTYNIMEID 278
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2b (deoxyribonuclease II beta [Source:MGI Symbol;Acc:MGI:1913283]) HSP 1 Score: 89.3521 bits (220), Expect = 9.885e-19 Identity = 52/154 (33.77%), Postives = 83/154 (53.90%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNL-VSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 + + G+WL HSVP FP + Y + + YGQ+ +C++ + + I QLL++Q IYS F P++F +LI +PR+ N S + V + + +N +HFAKS Y D+++ IA L L +TW+ + +L S C L Y V Sbjct: 129 NRTQGFWLIHSVPKFPPVHGYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTF--HWKLI-YMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQK-KKQELPSNCSLPYHV 278
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2b (deoxyribonuclease II beta [Source:MGI Symbol;Acc:MGI:1913283]) HSP 1 Score: 89.3521 bits (220), Expect = 9.885e-19 Identity = 52/154 (33.77%), Postives = 83/154 (53.90%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNL-VSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 + + G+WL HSVP FP + Y + + YGQ+ +C++ + + I QLL++Q IYS F P++F +LI +PR+ N S + V + + +N +HFAKS Y D+++ IA L L +TW+ + +L S C L Y V Sbjct: 129 NRTQGFWLIHSVPKFPPVHGYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTF--HWKLI-YMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQK-KKQELPSNCSLPYHV 278
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2a (deoxyribonuclease II alpha [Source:MGI Symbol;Acc:MGI:1329019]) HSP 1 Score: 62.3882 bits (150), Expect = 6.559e-10 Identity = 48/164 (29.27%), Postives = 75/164 (45.73%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDME--LISLLPRLIKNIRSKNLV-----SNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +D G+WL HSVP FP Y + +GQ+ +CVS+ T I +QL YP + + +E LP L I++++++ S+++ + FAK K+ DLYS +A L +L V+ W+N G L S C Y+V Sbjct: 101 LDQEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYT--------YPLVYDHKLEGFFAQKLPDLETVIKNQHVLHEPWNSSVI-LTSQAGATFQSFAKFGKFGDDLYSGWLAEALGTNLQVQFWQNSPG-ILPSNCSGAYQV 254
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Match: Dnase2a (deoxyribonuclease II alpha [Source:MGI Symbol;Acc:MGI:1329019]) HSP 1 Score: 62.3882 bits (150), Expect = 6.832e-10 Identity = 48/164 (29.27%), Postives = 75/164 (45.73%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDME--LISLLPRLIKNIRSKNLV-----SNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +D G+WL HSVP FP Y + +GQ+ +CVS+ T I +QL YP + + +E LP L I++++++ S+++ + FAK K+ DLYS +A L +L V+ W+N G L S C Y+V Sbjct: 122 LDQEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYT--------YPLVYDHKLEGFFAQKLPDLETVIKNQHVLHEPWNSSVI-LTSQAGATFQSFAKFGKFGDDLYSGWLAEALGTNLQVQFWQNSPG-ILPSNCSGAYQV 275
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|Q17778|NUC1_CAEEL (Deoxyribonuclease-2 OS=Caenorhabditis elegans OX=6239 GN=nuc-1 PE=3 SV=1) HSP 1 Score: 100.138 bits (248), Expect = 2.682e-21 Identity = 55/154 (35.71%), Postives = 82/154 (53.25%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 1647 D ++G WL HSVP FP +Y + + YGQ+ +C++ K LK I QL + IYSS PT+ D L + + +++ +T+ + +FAKS +++ DLY L+APTL L VETWR RGS++ C+L Y N Sbjct: 153 DGTSGVWLVHSVPLFPNPTKYEYPVSGHDYGQTMLCMTFKYAQLKSIGTQLFFNRPNIYSSNLPTNMAADNA--DLAKAIAGQYQKGQPFQSVIELETMAGYSFTNFAKSKEFNADLYDTLVAPTLKTDLVVETWR--RGSEIPLDCKLTYHAN 302
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|P34508|CRN6_CAEEL (Cell death-related nuclease 6 OS=Caenorhabditis elegans OX=6239 GN=crn-6 PE=2 SV=3) HSP 1 Score: 90.8929 bits (224), Expect = 2.787e-18 Identity = 53/151 (35.10%), Postives = 76/151 (50.33%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSK--LDSACE 1629 D TG+W+ HS+P FP ++ + F YGQ +C+S L I QQL Y P SF N ++S L N +S L S + K+L + HFAK+ ++ +DLYS + PTL S+ VETW + G + L S C+ Sbjct: 122 FDQYTGFWMIHSIPKFPSKDMFRFPSNAHYYGQMGICISYNTVSLATIAQQLFYYNTFTYQFNLPQSFANQFPVLSQLKNKEYN-KSPPLTSTKV-LKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCD 270
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|Q9QY48|DNS2B_MOUSE (Deoxyribonuclease-2-beta OS=Mus musculus OX=10090 GN=Dnase2b PE=2 SV=1) HSP 1 Score: 89.3521 bits (220), Expect = 6.915e-18 Identity = 52/154 (33.77%), Postives = 83/154 (53.90%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNL-VSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 + + G+WL HSVP FP + Y + + YGQ+ +C++ + + I QLL++Q IYS F P++F +LI +PR+ N S + V + + +N +HFAKS Y D+++ IA L L +TW+ + +L S C L Y V Sbjct: 129 NRTQGFWLIHSVPKFPPVHGYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTF--HWKLI-YMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQK-KKQELPSNCSLPYHV 278
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|Q9QZK9|DNS2B_RAT (Deoxyribonuclease-2-beta OS=Rattus norvegicus OX=10116 GN=Dnase2b PE=1 SV=1) HSP 1 Score: 88.1965 bits (217), Expect = 2.156e-17 Identity = 54/151 (35.76%), Postives = 78/151 (51.66%), Query Frame = 1 Query: 1198 GYWLTHSVPNFPM--ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 G+WL HS+P FP E Y + + Y QS +C+++K + + I QLL+ Q IYS F P F ELI + K+ SK + ++ +N LHFAKS Y D+++ IA L L VE+W+ + +L S C L Y V Sbjct: 133 GFWLIHSIPKFPPVPEKGYEYPSSGRQYAQSGLCITLKYSQYETIDSQLLVFQPNIYSCFIPNIFR--WELIHMPQMCAKSSASKIPSRRLTVLQSAQGLNFLHFAKSTFYTDDIFAAWIAQKLKVHLLVESWQR-KNHELPSNCSLPYHV 280
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Match: sp|P34387|TG198_CAEEL (Cell-death-related nuclease 7 OS=Caenorhabditis elegans OX=6239 GN=crn-7 PE=2 SV=2) HSP 1 Score: 84.3445 bits (207), Expect = 4.391e-16 Identity = 50/154 (32.47%), Postives = 79/154 (51.30%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSK-NLVSNILHF------KTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSAC 1626 D +TG+WL HSVPNFP + + YGQSF C S++ +L + + +QAT Y P + + P L KN+ +K +L + F KT+ + L+ +AK K+D D+++ LI+ +L VE+W NG G + + C Sbjct: 117 DSTTGFWLIHSVPNFPPIKSFSYPNTAEKYGQSFFCASMEVQHLTELAEHWKYIQATPYIINIPEKYA------TRFPTL-KNVEAKQSLPRSATQFWISKPIKTVQGVTLMAYAKHKKFDGDIWNDLISRQNKVTLAVESWLNGSGDDIHTTC 263
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A1S0TKK1 (Deoxyribonuclease II family protein OS=Loa loa OX=7209 GN=LOAG_13388 PE=4 SV=1) HSP 1 Score: 117.857 bits (294), Expect = 3.181e-25 Identity = 63/153 (41.18%), Postives = 89/153 (58.17%), Query Frame = 1 Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRL-IKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 D++G+WL HSVP FP YF+ + IYGQSFMCV++K T ++ + + + +Y P +F ++ L +L KNI + +L+ N FK+ + M +FAKS KY +DLYS +IA + SLF ETW NG LDS C YKV Sbjct: 110 DTSGFWLIHSVPKFPSLKHYFYAQNGEIYGQSFMCVTLKTTSIEIFAEAMKYIYPAVYGMNVPKTFLARFPFLNDLKQLKKKNIANTSLMKN---FKSNDGMIFYNFAKSDKYKKDLYSDMIARQMKVSLFTETWMNGGAKDLDSDCSTAYKV 259
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A1I7VP13 (Deoxyribonuclease II family protein OS=Loa loa OX=7209 PE=4 SV=1) HSP 1 Score: 117.857 bits (294), Expect = 5.859e-25 Identity = 63/153 (41.18%), Postives = 89/153 (58.17%), Query Frame = 1 Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRL-IKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 D++G+WL HSVP FP YF+ + IYGQSFMCV++K T ++ + + + +Y P +F ++ L +L KNI + +L+ N FK+ + M +FAKS KY +DLYS +IA + SLF ETW NG LDS C YKV Sbjct: 122 DTSGFWLIHSVPKFPSLKHYFYAQNGEIYGQSFMCVTLKTTSIEIFAEAMKYIYPAVYGMNVPKTFLARFPFLNDLKQLKKKNIANTSLMKN---FKSNDGMIFYNFAKSDKYKKDLYSDMIARQMKVSLFTETWMNGGAKDLDSDCSTAYKV 271
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A3P7EJU9 (Uncharacterized protein OS=Wuchereria bancrofti OX=6293 GN=WBA_LOCUS11946 PE=4 SV=1) HSP 1 Score: 115.931 bits (289), Expect = 2.761e-24 Identity = 61/152 (40.13%), Postives = 86/152 (56.58%), Query Frame = 1 Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +++G+WL HSVP FP Y + + YGQSF+CV++K T +K V + + +Y P +F N + L L K R N+ S + FK+ SM+ F+K+ KY++DLY LIA +N SLF ETW NG L+S C KYKV Sbjct: 125 NTSGFWLVHSVPKFPSLKRYSYTENGQTYGQSFLCVTLKMTSIKVFVNAMRYIYPEVYGINVPRNFLNTFPFLEDLKELKKK-RISNMSSLVQSFKSNGSMDFFDFSKTGKYNKDLYLDLIAKEMNVSLFAETWMNGAAKDLNSECTTKYKV 275
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A4E9F0C8 (Uncharacterized protein OS=Brugia malayi OX=6279 GN=Bma-crn-7.2 PE=4 SV=1) HSP 1 Score: 114.005 bits (284), Expect = 4.092e-24 Identity = 59/152 (38.82%), Postives = 87/152 (57.24%), Query Frame = 1 Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +++G+WL HSVP FP Y + + YGQSF+CV++K T +K + + +Y P +F N L+ L L K R N+ S + +FK+ +++ F+K+ KY++DLY LIA +N SLF ETW NG L+S C KYKV Sbjct: 67 NTSGFWLVHSVPKFPSLKRYSYAENGQTYGQSFLCVTLKTTSIKVFANAMRYIYPEVYGITVPRNFLNRFPLLEDLKELKKK-RISNMSSLLQNFKSNGNVDFFAFSKTGKYNKDLYLDLIAKEMNVSLFAETWMNGAAKDLNSECTTKYKV 217
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Match: A0A4E9EVB0 (Uncharacterized protein OS=Brugia malayi OX=6279 GN=Bma-crn-7.3 PE=4 SV=1) HSP 1 Score: 113.62 bits (283), Expect = 1.291e-23 Identity = 59/152 (38.82%), Postives = 87/152 (57.24%), Query Frame = 1 Query: 1189 DSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +++G+WL HSVP FP Y + + YGQSF+CV++K T +K + + +Y P +F N L+ L L K R N+ S + +FK+ +++ F+K+ KY++DLY LIA +N SLF ETW NG L+S C KYKV Sbjct: 110 NTSGFWLVHSVPKFPSLKRYSYAENGQTYGQSFLCVTLKTTSIKVFANAMRYIYPEVYGITVPRNFLNRFPLLEDLKELKKK-RISNMSSLLQNFKSNGNVDFFAFSKTGKYNKDLYLDLIAKEMNVSLFAETWMNGAAKDLNSECTTKYKV 260
BLAST of Deoxyribonuclease II family protein vs. Ensembl Cavefish
Match: dnase2 (deoxyribonuclease-2-alpha-like [Source:NCBI gene;Acc:103028211]) HSP 1 Score: 79.7221 bits (195), Expect = 1.393e-15 Identity = 48/164 (29.27%), Postives = 79/164 (48.17%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFP---MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIR--------SKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 DD G+WL HS P+FP E ++ + ++ + GQ+F+CV+ + I +QL + Q +Y P S + + + L + ++ R S + + + +L + FAK +D DLY +AP L L V+ WR G L+S C+ YKV Sbjct: 121 DDKQGFWLVHSTPHFPPLKTEGKFSYPESGTQNGQNFICVTYPLDRFETIGEQLKINQPHVYDCHIPESLASSVPSMVNLCKENQHRRNSSNAPPPSYSSANRSVSLLSLGGKEFISFAKGAAFDNDLYHSWVAPALQADLLVQFWRRSTGI-LESDCDPSYKV 283
BLAST of Deoxyribonuclease II family protein vs. Ensembl Cavefish
Match: dnase2b (deoxyribonuclease 2 beta [Source:NCBI gene;Acc:103030372]) HSP 1 Score: 78.9518 bits (193), Expect = 2.492e-15 Identity = 50/169 (29.59%), Postives = 82/169 (48.52%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLL-----PRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVNILFIDKIH 1671 D S G+W+THS+P+FP +E + + +YGQ+ C + K I QQL + +Y+ P + DM ++ L P + + + L S + L F+KS +Y D+Y+ +A TL L VE+W+ +L S C L Y ++L I ++H Sbjct: 140 DRSQGFWITHSIPHFPPFLEMGFGYPSTGKLYGQTVHCTTYSYEQFKKISQQLAYINPRVYNCSVPVPYHTDMAAMAQLCGGKRPTVAPRRKLEKLKSAL-------GETFLSFSKSHQYVDDIYAGWVAQTLRTDLLVESWQRDN-HQLPSNCSLPY--HVLNIKRVH 298
BLAST of Deoxyribonuclease II family protein vs. Ensembl Sea Lamprey
Match: dnase2 (deoxyribonuclease II, lysosomal [Source:ZFIN;Acc:ZDB-GENE-010724-16]) HSP 1 Score: 68.5514 bits (166), Expect = 1.096e-12 Identity = 46/160 (28.75%), Postives = 75/160 (46.88%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFP--MENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDM-ELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQ---DLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +D + G+WL HS P+FP + + + YGQSF+CVS I QL + YS + + +L +L + + S + ++ + FAK+ ++D DLY L+AP L SL++E+W +G G DS C ++ V Sbjct: 95 LDGTGGFWLVHSTPHFPPSVPGPFAWPHTALRYGQSFLCVSYGFDQFGDIALQLRYNEPDHYSCQVGAQLKDKLPDLQALCAKTKLQVES---ATRVVELTSSAGKTFRSFAKTHRFDDGASDLYVHLVAPNLKSSLYLESWVHGVGV-FDSNCSGEFCV 250
BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Match: dnase2 (deoxyribonuclease 2, lysosomal [Source:NCBI gene;Acc:101162954]) HSP 1 Score: 86.6557 bits (213), Expect = 9.300e-18 Identity = 49/160 (30.63%), Postives = 80/160 (50.00%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPME---NEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLL---PRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 +D + G+WL HS P+FP E EY++ + GQ+F+CV+ + I +QL + Q +Y P S + + ++ L RL + S+ + + + +++ N + FAK +D DLY +AP L L V+ W G L S C L +KV Sbjct: 124 LDQNQGFWLVHSTPHFPPERQAGEYYYPSSGVNNGQNFLCVTYPLKSFQTIGEQLQINQPHVYDCDIPESMVSLVPALAALCKKARLSDEVSSRPMSNRSMTLTSMDGTNFISFAKGASFDDDLYHGWVAPALQSDLLVQFWIRSTG-ILPSDCSLGWKV 282
BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Match: dnase2b (deoxyribonuclease-2-beta [Source:NCBI gene;Acc:101174093]) HSP 1 Score: 70.4774 bits (171), Expect = 1.479e-12 Identity = 45/163 (27.61%), Postives = 79/163 (48.47%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPM--ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLL-----PRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACEL-KYKVNI 1650 D + G+WL+HS+P+FP E Y + + + GQ+ +C++ + I QQL + Y+ P + + D+ ++ L P L + + L SN + F KS + D+Y+ +A L+ L VE+W+ +G L S C L ++ +NI Sbjct: 127 DHAKGFWLSHSIPHFPSFPERGYLYPSSGKLNGQTLLCMTYQYAQFLKIAQQLEYLYPRFYNCSVPAALSADLPQLAKLCAGSKPALASDKSMQPLFSN-------RGEKFISFVKSDHFVDDIYTGWVAQVLDTDLLVESWQT-QGRVLPSNCSLPRHAMNI 281
BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Match: ENSORLT00000036979.1 (deoxyribonuclease-2-alpha [Source:NCBI gene;Acc:101173852]) HSP 1 Score: 69.707 bits (169), Expect = 2.670e-12 Identity = 42/140 (30.00%), Postives = 71/140 (50.71%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPM-ENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELI---SLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETW 1590 +D TG WL+HS P FP ++ F+ ++ + Q+FMC++ + I QL + A + S P F +++ + S P+ + NL K++ + L FAK ++ DLYS LI TL +L+V++W Sbjct: 122 LDRQTGVWLSHSTPRFPTYRSQNFWPESGNANAQAFMCITFPYAQFEAIGLQLKYIHAYSFDSHVPQVFHMELQCVAQRSCYPKKEPWFKVANL-------KSMGGHSFLSFAKYTRFKDDLYSGLITNTLPSNLYVKSW 254
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000062594.1 (SMESG000062594.1) HSP 1 Score: 323.168 bits (827), Expect = 1.431e-104 Identity = 155/156 (99.36%), Postives = 156/156 (100.00%), Query Frame = 1 Query: 1180 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 1647 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQAT+YSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN Sbjct: 115 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATVYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKVN 270 HSP 2 Score: 160.999 bits (406), Expect = 1.381e-43 Identity = 75/77 (97.40%), Postives = 77/77 (100.00%), Query Frame = 2 Query: 197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKGV 427 FVAIKHPKSYNFVYLSSANADSHWKESNYDL+SEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKG+ Sbjct: 37 FVAIKHPKSYNFVYLSSANADSHWKESNYDLKSEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKGI 113
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000081036.1 (SMESG000081036.1) HSP 1 Score: 156.377 bits (394), Expect = 3.394e-42 Identity = 77/155 (49.68%), Postives = 103/155 (66.45%), Query Frame = 1 Query: 1180 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 N D+ TGYWL HSVP+FP Y + Q I GQSF+CVSIK + L +V+QLL+M A +YS ++P SFT + L L RL+ N+ S ++ SN++H T++ + L+HF KS + DLYS LIAP L SLFVE+W NG G + S C+L YKV Sbjct: 93 NFDEETGYWLIHSVPHFPPVRGYSYPDPQHINGQSFICVSIKTSDLNDVVKQLLLMYARVYSYYFPRSFTANTTLDYNLGRLVHNMHSPSIKSNVIHLNTISKVPLIHFGKSKLFANDLYSVLIAPQLKESLFVESWLNGNGGREPSNCQLTYKV 247 HSP 2 Score: 75.8702 bits (185), Expect = 1.244e-14 Identity = 40/79 (50.63%), Postives = 52/79 (65.82%), Query Frame = 2 Query: 197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNT--KCFYIYYNDDRPLSNSSTKGGHLKGV 427 ++AIK+P YNF YLSS + WK NY L S+KNL+A+TL Q+Y N K FY +YNDD+ + S + GHLKGV Sbjct: 13 YIAIKYPGVYNFFYLSSETNGNTWKLPNYALNSDKNLVALTLSQAYSAENNKDKTFYAFYNDDKSKNVSGSNDGHLKGV 91
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000081036.1 (SMESG000081036.1) HSP 1 Score: 156.377 bits (394), Expect = 5.122e-42 Identity = 77/155 (49.68%), Postives = 103/155 (66.45%), Query Frame = 1 Query: 1180 NMDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 N D+ TGYWL HSVP+FP Y + Q I GQSF+CVSIK + L +V+QLL+M A +YS ++P SFT + L L RL+ N+ S ++ SN++H T++ + L+HF KS + DLYS LIAP L SLFVE+W NG G + S C+L YKV Sbjct: 115 NFDEETGYWLIHSVPHFPPVRGYSYPDPQHINGQSFICVSIKTSDLNDVVKQLLLMYARVYSYYFPRSFTANTTLDYNLGRLVHNMHSPSIKSNVIHLNTISKVPLIHFGKSKLFANDLYSVLIAPQLKESLFVESWLNGNGGREPSNCQLTYKV 269 HSP 2 Score: 75.8702 bits (185), Expect = 1.491e-14 Identity = 40/79 (50.63%), Postives = 52/79 (65.82%), Query Frame = 2 Query: 197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNT--KCFYIYYNDDRPLSNSSTKGGHLKGV 427 ++AIK+P YNF YLSS + WK NY L S+KNL+A+TL Q+Y N K FY +YNDD+ + S + GHLKGV Sbjct: 35 YIAIKYPGVYNFFYLSSETNGNTWKLPNYALNSDKNLVALTLSQAYSAENNKDKTFYAFYNDDKSKNVSGSNDGHLKGV 113
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000062993.1 (SMESG000062993.1) HSP 1 Score: 131.339 bits (329), Expect = 4.067e-33 Identity = 72/154 (46.75%), Postives = 98/154 (63.64%), Query Frame = 1 Query: 1186 DDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNI-LHFKTLNSMNLLHFAKSPKYDQDLYSKLIAPTLNGSLFVETWRNGRGSKLDSACELKYKV 1644 D + G+WL HSVP FP Y + KA+ IYGQSF+CVS+++ L+ IV QLL+MQ+T+YS P +F + +L +LL I N K +N+ + KTL S+ L+HF KS + QDLYS L+AP L S+ VE+W RG K+DS C Y V Sbjct: 111 DINNGFWLIHSVPLFPTFGNYTYGKAEEIYGQSFICVSLESENLQNIVIQLLLMQSTVYSYNLPENFPVNDKLKTLLTNFINNKNMKIQQTNMTIIMKTLKSLPLVHFGKSYSFGQDLYSGLVAPGLQASIMVESWI--RGEKVDSTCGTDYHV 262 HSP 2 Score: 68.5514 bits (166), Expect = 3.958e-12 Identity = 38/90 (42.22%), Postives = 54/90 (60.00%), Query Frame = 2 Query: 197 FVAIKHPKSYNFVYLSSANADSHWKESNYDLRSEKNLIAITLQQSYLHCNTKCFYIYYNDDRPLSNSSTKGGHLKGVKFIKN*NHFLSLH 466 F+ +K PKSY FVY+SS + W S +DL S+ N+I T++Q+Y ++ FY YYND+ P S++ GHLKGV N F +H Sbjct: 34 FIGLKFPKSYKFVYISSQSET--WTTSKFDLSSKNNMIGWTIEQTYSSHQSQSFYAYYNDETPKFTYSSR-GHLKGVISFDINNGFWLIH 120
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Match: SMESG000081051.1 (SMESG000081051.1) HSP 1 Score: 101.679 bits (252), Expect = 5.592e-24 Identity = 49/116 (42.24%), Postives = 70/116 (60.34%), Query Frame = 1 Query: 1183 MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQQLLMMQATIYSSFYPTSFTNDMELISLLPRLIKNIRSKNLVSNILHFKTLNSMNLLHFAKSPKYDQ 1530 D S GYWL HSVP FP NEY + Q +GQSF+CVS+K L +V QLL+M +YS F P F+ + L+ + L+ N K+ SN+ +F T+ + NL+HF KS +++ Sbjct: 115 FDKSEGYWLVHSVPKFPFPNEYKYGSGQLKFGQSFICVSLKFQNLNSLVDQLLIMTTNVYSYFVPEGFSQNSSLMDKINSLVNNSIKKSKDSNVFNFNTVKNFNLIHFGKSRLFNR 230 The following BLAST results are available for this feature:
BLAST of Deoxyribonuclease II family protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of Deoxyribonuclease II family protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Deoxyribonuclease II family protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Deoxyribonuclease II family protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of Deoxyribonuclease II family protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of Deoxyribonuclease II family protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of Deoxyribonuclease II family protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Deoxyribonuclease II family protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Deoxyribonuclease II family protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Deoxyribonuclease II family protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Deoxyribonuclease II family protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Deoxyribonuclease II family protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Deoxyribonuclease II family protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of Deoxyribonuclease II family protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015950 ID=SMED30015950|Name=Deoxyribonuclease II family protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2149bpback to top protein sequence of SMED30015950-orf-1 >SMED30015950-orf-1 ID=SMED30015950-orf-1|Name=SMED30015950-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=165bp MDDSTGYWLTHSVPNFPMENEYFFNKAQSIYGQSFMCVSIKNTYLKPIVQback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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