Centrin-1

Overview
NameCentrin-1
Smed IDSMED30015945
Length (bp)599
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Centrin-1 (SMED30015945) t-SNE clustered cells

Violin plots show distribution of expression levels for Centrin-1 (SMED30015945) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Centrin-1 (SMED30015945) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Centrin-1 (SMED30015945) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30015945

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30015945h1SMcG0004755 Contig42390uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015945h1SMcG0004755 Contig42390newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30015945h1SMcG0004755 dd_Smed_v4_3644_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30015945h1SMcG0004755 dd_Smed_v4_3644_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30015945h1SMcG0004755 dd_Smed_v4_3644_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30015945h1SMcG0004755 dd_Smed_v4_3644_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30015945h1SMcG0004755 dd_Smed_v4_3644_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30015945h1SMcG0004755 dd_Smed_v6_3644_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30015945h1SMcG0004755 dd_Smed_v4_3644_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Centrin-1 vs. Ensembl Human
Match: CETN2 (centrin 2 [Source:HGNC Symbol;Acc:HGNC:1867])

HSP 1 Score: 263.848 bits (673), Expect = 1.862e-90
Identity = 132/172 (76.74%), Postives = 154/172 (89.53%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +    +Q+K+     +PELTEEQKQE+REAFDLFDADG+GTID+KELKVAMRALGFEPKKEE++K+I++ D EG G + F DFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE++EQEFLRIMKKT+LY
Sbjct:    3 SNFKKANMASSSQRKRMSP--KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. Ensembl Human
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 262.307 bits (669), Expect = 8.443e-90
Identity = 133/172 (77.33%), Postives = 151/172 (87.79%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +  KK SA    QK+K     +PELTE+QKQEVREAFDLFD DGSGTID KELKVAMRALGFEP+KEE++K+I++ D EG G I F+DFL++MTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGENLTDEELQEMIDEADRD DGE+NE+EFLRIMKKT+LY
Sbjct:    3 SGFKKPSAASTGQKRK--VAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. Ensembl Human
Match: CETN3 (centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868])

HSP 1 Score: 176.407 bits (446), Expect = 5.451e-56
Identity = 89/145 (61.38%), Postives = 115/145 (79.31%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R EL+EEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + E+D  EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN++DEEL+ MI+E D+D DGEIN++EF+ IM
Sbjct:   19 RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIM 163          
BLAST of Centrin-1 vs. Ensembl Human
Match: CETN3 (centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868])

HSP 1 Score: 164.466 bits (415), Expect = 4.469e-51
Identity = 84/136 (61.76%), Postives = 107/136 (78.68%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEI 491
            R EL+EEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + E+D  EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN++DEEL+ MI+E D+D DGEI
Sbjct:   19 RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEI 154          
BLAST of Centrin-1 vs. Ensembl Human
Match: CETN3 (centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868])

HSP 1 Score: 162.925 bits (411), Expect = 7.518e-51
Identity = 83/135 (61.48%), Postives = 106/135 (78.52%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGE 488
            R EL+EEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + E+D  EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN++DEEL+ MI+E D+D DGE
Sbjct:   19 RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGE 153          
BLAST of Centrin-1 vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 140.584 bits (353), Expect = 1.085e-42
Identity = 73/143 (51.05%), Postives = 99/143 (69.23%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+ +M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          

HSP 2 Score: 58.5362 bits (140), Expect = 5.126e-11
Identity = 36/97 (37.11%), Postives = 55/97 (56.70%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F++MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTTK 149          

HSP 3 Score: 58.5362 bits (140), Expect = 5.508e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          
BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 119.783 bits (299), Expect = 2.581e-34
Identity = 64/145 (44.14%), Postives = 95/145 (65.52%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            +LT E+  E REAF +FD DG+GTI  KEL +AMR+LG  P ++E+ ++I + DI+G G IEF +F  MM + M E D+ E I +AF++FD D  G I+ +  +     +G   ++EE+ EMI E D D DGEI+ +EF+++M  
Sbjct:   17 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMKETDS-EMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSN 160          

HSP 2 Score: 53.9138 bits (128), Expect = 3.339e-9
Identity = 25/72 (34.72%), Postives = 46/72 (63.89%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            + E   + +REAF +FD DG+G I  +E +  M  +G +  +EEV ++I + D++G G I++ +F+ MM+ +
Sbjct:   90 MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 161          
BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 119.398 bits (298), Expect = 5.052e-34
Identity = 64/145 (44.14%), Postives = 95/145 (65.52%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            +LT E+  E REAF +FD DG+GTI  KEL +AMR+LG  P ++E+ ++I + DI+G G IEF +F  MM + M E D+ E I +AF++FD D  G I+ +  +     +G   ++EE+ EMI E D D DGEI+ +EF+++M  
Sbjct:   36 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMKETDS-EMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSN 179          

HSP 2 Score: 53.9138 bits (128), Expect = 5.196e-9
Identity = 25/72 (34.72%), Postives = 46/72 (63.89%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            + E   + +REAF +FD DG+G I  +E +  M  +G +  +EEV ++I + D++G G I++ +F+ MM+ +
Sbjct:  109 MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 180          
BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-4 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:G5EDZ8])

HSP 1 Score: 111.694 bits (278), Expect = 5.498e-31
Identity = 64/158 (40.51%), Postives = 97/158 (61.39%), Query Frame = 3
Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILK-AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            G NQ       D  E T E+ QE  +AF LFD DG+ T++IKEL  AMR LG  P +EE+  ++ +YD++G G I+F +F  MM  K   K+T +E+++ AFK+FD D  G I+ +  K     +GE  ++EE+ E+I E D+D D +I+  EF+ ++
Sbjct:    5 GTNQSV---CSDADEFTPEELQEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMM--KEMNKETDQELIRLAFKVFDKDGNGYITAQEFKHFMTTMGERFSEEEVDEIIREVDKDGDEQIDLDEFVNMV 157          

HSP 2 Score: 51.6026 bits (122), Expect = 2.824e-8
Identity = 28/67 (41.79%), Postives = 42/67 (62.69%), Query Frame = 3
Query:  330 EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTN 530
            +E  +AFKLFD D    ++ K L    + LG N T+EEL  M++E D D +G+I+  EF ++MK+ N
Sbjct:   23 QEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMMKEMN 89          
BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-4 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:G5EDZ8])

HSP 1 Score: 112.464 bits (280), Expect = 5.969e-31
Identity = 64/158 (40.51%), Postives = 97/158 (61.39%), Query Frame = 3
Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILK-AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            G NQ       D  E T E+ QE  +AF LFD DG+ T++IKEL  AMR LG  P +EE+  ++ +YD++G G I+F +F  MM  K   K+T +E+++ AFK+FD D  G I+ +  K     +GE  ++EE+ E+I E D+D D +I+  EF+ ++
Sbjct:   31 GTNQSV---CSDADEFTPEELQEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMM--KEMNKETDQELIRLAFKVFDKDGNGYITAQEFKHFMTTMGERFSEEEVDEIIREVDKDGDEQIDLDEFVNMV 183          

HSP 2 Score: 52.373 bits (124), Expect = 2.283e-8
Identity = 28/67 (41.79%), Postives = 42/67 (62.69%), Query Frame = 3
Query:  330 EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTN 530
            +E  +AFKLFD D    ++ K L    + LG N T+EEL  M++E D D +G+I+  EF ++MK+ N
Sbjct:   49 QEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMMKEMN 115          
BLAST of Centrin-1 vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332630)

HSP 1 Score: 224.172 bits (570), Expect = 4.937e-75
Identity = 111/161 (68.94%), Postives = 140/161 (86.96%), Query Frame = 3
Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
             Q+ +  SG + EL+E QK +++EAFDLFD +G+G I++KELKVA+RALGFEPKKEE++++I+D D +  G I F+ FL +MT KMAEKDTKEEILKAF+LFDDD+TGKISF+NLKRVA+ELGE LTDEEL+EMIDEAD DNDGE+N++EFLRIMKKT+LY
Sbjct:   22 TQQGRKKSGPKFELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182          
BLAST of Centrin-1 vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332632)

HSP 1 Score: 224.172 bits (570), Expect = 4.937e-75
Identity = 111/161 (68.94%), Postives = 140/161 (86.96%), Query Frame = 3
Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
             Q+ +  SG + EL+E QK +++EAFDLFD +G+G I++KELKVA+RALGFEPKKEE++++I+D D +  G I F+ FL +MT KMAEKDTKEEILKAF+LFDDD+TGKISF+NLKRVA+ELGE LTDEEL+EMIDEAD DNDGE+N++EFLRIMKKT+LY
Sbjct:   22 TQQGRKKSGPKFELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182          
BLAST of Centrin-1 vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332631)

HSP 1 Score: 224.172 bits (570), Expect = 4.937e-75
Identity = 111/161 (68.94%), Postives = 140/161 (86.96%), Query Frame = 3
Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
             Q+ +  SG + EL+E QK +++EAFDLFD +G+G I++KELKVA+RALGFEPKKEE++++I+D D +  G I F+ FL +MT KMAEKDTKEEILKAF+LFDDD+TGKISF+NLKRVA+ELGE LTDEEL+EMIDEAD DNDGE+N++EFLRIMKKT+LY
Sbjct:   22 TQQGRKKSGPKFELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182          
BLAST of Centrin-1 vs. Ensembl Fly
Match: CG31802 (gene:FBgn0051802 transcript:FBtr0081058)

HSP 1 Score: 179.104 bits (453), Expect = 3.622e-57
Identity = 93/173 (53.76%), Postives = 128/173 (73.99%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRP--ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNL 533
             S+   SA   ++ KK      P  +L+  QK ++++AFDLFD   +G I+ KEL+VA+RALGFEPKKE++++++ + D +  G I F+DFL +M  KMAEKD+ ++++KAF  FDDD TG ISF NLKRVAKELGE LTDEELQEMIDEA+   DGE++++EFL ++KKTNL
Sbjct:   13 ASVMHSSASISSRAKKSKKPKLPTFDLSLSQKVDIKKAFDLFDTQCTGFIETKELRVAIRALGFEPKKEDIKRMMDEIDKDKTGRIAFNDFLYLMRLKMAEKDSNQDMMKAFSFFDDDRTGGISFLNLKRVAKELGEQLTDEELQEMIDEANVSGDGEVSKEEFLNLIKKTNL 185          
BLAST of Centrin-1 vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 140.584 bits (353), Expect = 1.552e-42
Identity = 73/143 (51.05%), Postives = 99/143 (69.23%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+ +M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146          

HSP 2 Score: 58.5362 bits (140), Expect = 6.243e-11
Identity = 36/97 (37.11%), Postives = 55/97 (56.70%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F++MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 149          

HSP 3 Score: 58.5362 bits (140), Expect = 7.062e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          
BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn4 (centrin 4 [Source:ZFIN;Acc:ZDB-GENE-030826-21])

HSP 1 Score: 277.33 bits (708), Expect = 5.666e-96
Identity = 141/173 (81.50%), Postives = 155/173 (89.60%), Query Frame = 3
Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S  + S+   NQ+KK G   +PELTEEQKQE++EAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G+I FSDFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    1 MASGFRKSSASANQRKKAGP--KPELTEEQKQEIKEAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGVIGFSDFLSMMTQKMSEKDSKEEILKAFRLFDDDCTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171          
BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn2 (centrin, EF-hand protein, 2 [Source:ZFIN;Acc:ZDB-GENE-091118-94])

HSP 1 Score: 261.536 bits (667), Expect = 9.288e-90
Identity = 131/172 (76.16%), Postives = 151/172 (87.79%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            TS K+ S G +  +KK     + ELTEEQKQE+REAF+LFD DGSG I++KELKVAMRALGFEPKKEE++K+IA+ D E  G I F+DFLS+MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N+QEFLRIMKKT+LY
Sbjct:    3 TSPKRPSLGAVAPRKKASP--KSELTEEQKQEIREAFELFDTDGSGYIEVKELKVAMRALGFEPKKEEIKKMIAEVDKEATGKISFTDFLSVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQQEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn3 (centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152])

HSP 1 Score: 178.718 bits (452), Expect = 3.286e-57
Identity = 93/145 (64.14%), Postives = 114/145 (78.62%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELT+EQK E++EAF+LFD D    ID  ELKVAMRALGFE KK +V K++ DYD EG G I F DF  ++T  + E+D KEEILKAFKLFDDDETGKIS +NL+RVA+ELGE+++DE+L+ MIDE D D DGEIN+ EF+ IM
Sbjct:   19 RRELTDEQKDEIKEAFELFDTDKDKEIDYHELKVAMRALGFEVKKVDVLKILKDYDREGTGKISFEDFREVVTDMILERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIM 163          

HSP 2 Score: 49.6766 bits (117), Expect = 2.392e-7
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+E+ +AF LFD D +G I ++ L+   R LG +   E++R +I ++D +G G I   +F+S+MT
Sbjct:   95 LERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIMT 164          
BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn3 (centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152])

HSP 1 Score: 178.333 bits (451), Expect = 3.972e-57
Identity = 93/145 (64.14%), Postives = 114/145 (78.62%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELT+EQK E++EAF+LFD D    ID  ELKVAMRALGFE KK +V K++ DYD EG G I F DF  ++T  + E+D KEEILKAFKLFDDDETGKIS +NL+RVA+ELGE+++DE+L+ MIDE D D DGEIN+ EF+ IM
Sbjct:   15 RRELTDEQKDEIKEAFELFDTDKDKEIDYHELKVAMRALGFEVKKVDVLKILKDYDREGTGKISFEDFREVVTDMILERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIM 159          

HSP 2 Score: 49.6766 bits (117), Expect = 2.175e-7
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+E+ +AF LFD D +G I ++ L+   R LG +   E++R +I ++D +G G I   +F+S+MT
Sbjct:   91 LERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIMT 160          
BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: calm3a (calmodulin 3a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-5590])

HSP 1 Score: 142.124 bits (357), Expect = 4.647e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          

HSP 2 Score: 58.5362 bits (140), Expect = 8.375e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          

HSP 3 Score: 58.151 bits (139), Expect = 1.385e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149          
BLAST of Centrin-1 vs. Ensembl Xenopus
Match: cetn1 (centrin 1 [Source:NCBI gene;Acc:549903])

HSP 1 Score: 267.7 bits (683), Expect = 5.594e-92
Identity = 136/172 (79.07%), Postives = 152/172 (88.37%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK S G   Q+KK     +PELTEEQKQE+REAFDLFD DG+GTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F DF+S MTQKMAEKD+KEEI+KAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNYKKPSLGVTTQRKKPVP--KPELTEEQKQEIREAFDLFDTDGAGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGTGKISFGDFMSAMTQKMAEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. Ensembl Xenopus
Match: dtl (denticleless E3 ubiquitin protein ligase homolog [Source:Xenbase;Acc:XB-GENE-985623])

HSP 1 Score: 263.077 bits (671), Expect = 2.916e-90
Identity = 132/173 (76.30%), Postives = 154/173 (89.02%), Query Frame = 3
Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S+ +    G  Q+++ G+  +PELTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+I+D D +G GII+F DFLS+MTQKM+EKD+KEEI+KAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIM+KT+L 
Sbjct:    1 MASVLRKPGLGATQRRRIGA--KPELTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEMKKIISDTDKDGSGIIDFEDFLSLMTQKMSEKDSKEEIMKAFRLFDDDNTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMRKTSLC 171          
BLAST of Centrin-1 vs. Ensembl Xenopus
Match: cetn1 (centrin 1 [Source:NCBI gene;Acc:549903])

HSP 1 Score: 261.151 bits (666), Expect = 1.302e-89
Identity = 129/151 (85.43%), Postives = 142/151 (94.04%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +PELTEEQKQE+REAFDLFD DG+GTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F DF+S MTQKMAEKD+KEEI+KAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    7 KPELTEEQKQEIREAFDLFDTDGAGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGTGKISFGDFMSAMTQKMAEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 157          
BLAST of Centrin-1 vs. Ensembl Xenopus
Match: dtl (denticleless E3 ubiquitin protein ligase homolog [Source:Xenbase;Acc:XB-GENE-985623])

HSP 1 Score: 260.766 bits (665), Expect = 3.076e-89
Identity = 130/163 (79.75%), Postives = 150/163 (92.02%), Query Frame = 3
Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            G  Q+++ G+  +PELTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+I+D D +G GII+F DFLS+MTQKM+EKD+KEEI+KAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIM+KT+L 
Sbjct:   12 GATQRRRIGA--KPELTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEMKKIISDTDKDGSGIIDFEDFLSLMTQKMSEKDSKEEIMKAFRLFDDDNTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMRKTSLC 172          
BLAST of Centrin-1 vs. Ensembl Xenopus
Match: rab38 (RAB38, member RAS oncogene family [Source:Xenbase;Acc:XB-GENE-480756])

HSP 1 Score: 177.563 bits (449), Expect = 1.538e-56
Identity = 91/145 (62.76%), Postives = 116/145 (80.00%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELTEEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + ++D +EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN+TDEEL+ MI+E D+D DGEIN++EFL IM
Sbjct:   19 RRELTEEQKQEIKDAFELFDTDKDKAIDYHELKVAMRALGFDVKKADVLKILKDYDGETTGKITFDDFNEVVTDLILDRDPQEEILKAFKLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIEEFDKDGDGEINQEEFLSIM 163          
BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 265.774 bits (678), Expect = 2.030e-91
Identity = 134/172 (77.91%), Postives = 154/172 (89.53%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +     Q+K+     +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNFKKTTMASSAQRKRMSP--KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 262.692 bits (670), Expect = 2.165e-90
Identity = 130/151 (86.09%), Postives = 145/151 (96.03%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:   13 KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 163          
BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 262.692 bits (670), Expect = 2.165e-90
Identity = 130/151 (86.09%), Postives = 145/151 (96.03%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:   13 KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 163          
BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn1 (centrin 1 [Source:MGI Symbol;Acc:MGI:1347086])

HSP 1 Score: 259.996 bits (663), Expect = 3.814e-89
Identity = 129/172 (75.00%), Postives = 153/172 (88.95%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ +K +    + K+K G   +PELTE+QKQEVREAFDLFD+DGSGTID+KELKVAMRALGFEP+KEE++K+I++ D E  G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEMIDEADRD DGE+NE+EFL+IMKKTNLY
Sbjct:    3 STFRKSNVASTSYKRKVGP--KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172          
BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn1 (centrin 1 [Source:MGI Symbol;Acc:MGI:1347086])

HSP 1 Score: 259.996 bits (663), Expect = 3.814e-89
Identity = 129/172 (75.00%), Postives = 153/172 (88.95%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ +K +    + K+K G   +PELTE+QKQEVREAFDLFD+DGSGTID+KELKVAMRALGFEP+KEE++K+I++ D E  G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEMIDEADRD DGE+NE+EFL+IMKKTNLY
Sbjct:    3 STFRKSNVASTSYKRKVGP--KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172          
BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q32LE3|CETN1_BOVIN (Centrin-1 OS=Bos taurus OX=9913 GN=CETN1 PE=2 SV=1)

HSP 1 Score: 273.863 bits (699), Expect = 8.718e-94
Identity = 138/172 (80.23%), Postives = 155/172 (90.12%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K +    +QK+K G   +PELTEEQKQEVREAFDLFDADGSGTID+KELKVAMRALGFEP+KEE++++IAD D EG G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NE EFLRIMKKTNLY
Sbjct:    3 SSYRKPTVASTSQKRKVGP--KPELTEEQKQEVREAFDLFDADGSGTIDVKELKVAMRALGFEPRKEEMKRMIADVDKEGTGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEDEFLRIMKKTNLY 172          
BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q2TBN3|CETN2_BOVIN (Centrin-2 OS=Bos taurus OX=9913 GN=CETN2 PE=2 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 3.940e-91
Identity = 133/172 (77.33%), Postives = 154/172 (89.53%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +     Q+K+     +PELTEEQKQE+REAFDLFDADG+GTID+KELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENL+DEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNFKKANMASTTQRKRMSP--KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLSDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q9R1K9|CETN2_MOUSE (Centrin-2 OS=Mus musculus OX=10090 GN=Cetn2 PE=1 SV=1)

HSP 1 Score: 265.774 bits (678), Expect = 1.420e-90
Identity = 134/172 (77.91%), Postives = 154/172 (89.53%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +     Q+K+     +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNFKKTTMASSAQRKRMSP--KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|P41208|CETN2_HUMAN (Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1)

HSP 1 Score: 263.848 bits (673), Expect = 8.942e-90
Identity = 132/172 (76.74%), Postives = 154/172 (89.53%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +    +Q+K+     +PELTEEQKQE+REAFDLFDADG+GTID+KELKVAMRALGFEPKKEE++K+I++ D EG G + F DFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE++EQEFLRIMKKT+LY
Sbjct:    3 SNFKKANMASSSQRKRMSP--KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q12798|CETN1_HUMAN (Centrin-1 OS=Homo sapiens OX=9606 GN=CETN1 PE=1 SV=1)

HSP 1 Score: 262.307 bits (669), Expect = 4.055e-89
Identity = 133/172 (77.33%), Postives = 151/172 (87.79%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +  KK SA    QK+K     +PELTE+QKQEVREAFDLFD DGSGTID KELKVAMRALGFEP+KEE++K+I++ D EG G I F+DFL++MTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGENLTDEELQEMIDEADRD DGE+NE+EFLRIMKKT+LY
Sbjct:    3 SGFKKPSAASTGQKRK--VAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY 172          
BLAST of Centrin-1 vs. TrEMBL
Match: A0A444U7H9 (Centrin-1 OS=Acipenser ruthenus OX=7906 GN=EOD39_1794 PE=4 SV=1)

HSP 1 Score: 281.567 bits (719), Expect = 3.519e-94
Identity = 142/172 (82.56%), Postives = 158/172 (91.86%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            TS +K  A G NQ++K G+G++PEL EEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I+F+DFLSMMTQKM+EKDTKEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKT+LY
Sbjct:   16 TSYRK-PAFGPNQRRKPGTGNKPELAEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADVDKEGSGTIDFNDFLSMMTQKMSEKDTKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTSLY 186          
BLAST of Centrin-1 vs. TrEMBL
Match: F1R789 (Centrin 4 OS=Danio rerio OX=7955 GN=cetn4 PE=4 SV=1)

HSP 1 Score: 277.33 bits (708), Expect = 1.268e-92
Identity = 141/173 (81.50%), Postives = 155/173 (89.60%), Query Frame = 3
Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S  + S+   NQ+KK G   +PELTEEQKQE++EAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G+I FSDFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    1 MASGFRKSSASANQRKKAGP--KPELTEEQKQEIKEAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGVIGFSDFLSMMTQKMSEKDSKEEILKAFRLFDDDCTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171          
BLAST of Centrin-1 vs. TrEMBL
Match: B1P0R9 (Centrin2 (Fragment) OS=Danio rerio OX=7955 GN=cetn4 PE=2 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 1.580e-92
Identity = 141/173 (81.50%), Postives = 155/173 (89.60%), Query Frame = 3
Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S  + S+   NQ+KK G   +PELTEEQKQE++EAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G+I FSDFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    1 MASGFRKSSASANQRKKAGP--KPELTEEQKQEIKEAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGVIGFSDFLSMMTQKMSEKDSKEEILKAFRLFDDDCTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171          
BLAST of Centrin-1 vs. TrEMBL
Match: A0A4W4F0V6 (Uncharacterized protein OS=Electrophorus electricus OX=8005 GN=LOC113577166 PE=4 SV=1)

HSP 1 Score: 276.174 bits (705), Expect = 3.366e-92
Identity = 141/172 (81.98%), Postives = 157/172 (91.28%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K SA  +NQ+KK G   +P+LTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I+F+DFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    4 SSFRKPSAT-LNQRKKAGP--KPDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTIDFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 172          
BLAST of Centrin-1 vs. TrEMBL
Match: W5P165 (Centrin 1 OS=Ovis aries OX=9940 GN=CETN1 PE=4 SV=1)

HSP 1 Score: 275.789 bits (704), Expect = 4.833e-92
Identity = 139/172 (80.81%), Postives = 155/172 (90.12%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S KK +    +QK+K G   +PELTEEQKQEVREAFDLFDADGSGTID+KELKVAMRALGFEP+KEE++++IAD D EG G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NE EFLRIMKKTNLY
Sbjct:    3 SSFKKSTVASTSQKRKVGP--KPELTEEQKQEVREAFDLFDADGSGTIDVKELKVAMRALGFEPRKEEMKRMIADVDKEGTGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEDEFLRIMKKTNLY 172          
BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn4 (caltractin [Source:NCBI gene;Acc:103037928])

HSP 1 Score: 272.707 bits (696), Expect = 2.682e-94
Identity = 141/172 (81.98%), Postives = 155/172 (90.12%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K SA   NQ+KKGG   + +LTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F+DFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    4 SSFRKPSATA-NQRKKGGP--KVDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTINFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 172          
BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn4 (caltractin [Source:NCBI gene;Acc:103037928])

HSP 1 Score: 272.707 bits (696), Expect = 2.956e-94
Identity = 141/172 (81.98%), Postives = 155/172 (90.12%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K SA   NQ+KKGG   + +LTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F+DFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    3 SSFRKPSATA-NQRKKGGP--KVDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTINFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171          
BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn2 (centrin-1 [Source:NCBI gene;Acc:103028142])

HSP 1 Score: 260.766 bits (665), Expect = 1.570e-89
Identity = 131/172 (76.16%), Postives = 151/172 (87.79%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            TS K+ S G    +KK  +  +PELTEE KQE+REAF+LFD DGSG I++KELKVAMRALGFEPKKEE++K+IAD D +G G I F+DFL++MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N+QEFLRIMKKT LY
Sbjct:    3 TSAKRPSLGAAAPRKK--TSPKPELTEEMKQEIREAFELFDTDGSGHIEVKELKVAMRALGFEPKKEEIKKMIADVDKDGTGKISFNDFLTIMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQQEFLRIMKKTCLY 172          
BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn3 (centrin 3 [Source:NCBI gene;Acc:103024517])

HSP 1 Score: 181.8 bits (460), Expect = 2.120e-58
Identity = 94/145 (64.83%), Postives = 116/145 (80.00%), Query Frame = 3
Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELTEEQK E++EAF+LFD D    ID  ELKVAMRALGFE KK +V K++ DYD EG G I F DF  ++T ++ E+D KEEILKAFKLFDDDE+GKIS +NL+RVA+ELGE+++DEEL+ MIDE D D DGEIN++EF+ IM
Sbjct:   19 RRELTEEQKDEIKEAFELFDTDKDKEIDYHELKVAMRALGFEVKKVDVLKILKDYDREGTGKITFEDFREVVTDRILERDPKEEILKAFKLFDDDESGKISLRNLRRVARELGEDMSDEELRAMIDEFDTDGDGEINQEEFVSIM 163          

HSP 2 Score: 51.6026 bits (122), Expect = 3.945e-8
Identity = 28/70 (40.00%), Postives = 44/70 (62.86%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+E+ +AF LFD D SG I ++ L+   R LG +   EE+R +I ++D +G G I   +F+S+MT
Sbjct:   95 LERDPKEEILKAFKLFDDDESGKISLRNLRRVARELGEDMSDEELRAMIDEFDTDGDGEINQEEFVSIMT 164          
BLAST of Centrin-1 vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 142.124 bits (357), Expect = 3.938e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          

HSP 2 Score: 58.5362 bits (140), Expect = 7.098e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          

HSP 3 Score: 58.151 bits (139), Expect = 1.174e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149          
BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 271.552 bits (693), Expect = 2.170e-94
Identity = 138/179 (77.09%), Postives = 159/179 (88.83%), Query Frame = 3
Query:    3 LYKSYMTSLKK-GSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            L  S  T  +K G AGG  +KK   SG +PEL+EEQKQE++EAFDLFDADGSGTID+KELKVAMRALGFEPKKEE++K+IAD+D +G G I F+DFL+MMTQKM+EKD++EEILKAF+LFDDDETGKISFKNLKRVAKELGE LTDEELQEMIDEADRD DGEINE+EFLR+MKKT+LY
Sbjct:    8 LLSSQATGFRKLGGAGGAQRKK---SGPKPELSEEQKQEIKEAFDLFDADGSGTIDVKELKVAMRALGFEPKKEEIKKMIADFDKDGSGKINFNDFLAMMTQKMSEKDSREEILKAFRLFDDDETGKISFKNLKRVAKELGETLTDEELQEMIDEADRDGDGEINEEEFLRVMKKTSLY 183          
BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: cetn3 (centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152])

HSP 1 Score: 166.777 bits (421), Expect = 3.172e-53
Identity = 85/151 (56.29%), Postives = 115/151 (76.16%), Query Frame = 3
Query:   66 KGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            KG    R E+TEEQKQE++EAF+LFD D  G ID  ELKVA+RALGFE  K +V K++ DYD E  G I + DF  +MT+++ E+D  +E+LKAF+LFD+ E+G+I  ++L+RVA+ELGE ++DEEL+ MIDE D D DGEIN++EF+ IM
Sbjct:   14 KGKRRRRREMTEEQKQEIQEAFELFDTDKDGAIDYHELKVAIRALGFEVSKADVIKIMKDYDREDTGKISYDDFCEVMTERVLERDPLDEVLKAFRLFDEGESGRIGVRDLRRVARELGETVSDEELRAMIDEFDTDGDGEINQEEFIAIM 164          
BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006008.1 (pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-1 gene:ENSPMAG00000005430.1 transcript:ENSPMAT00000006008.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 143.28 bits (360), Expect = 2.663e-44
Identity = 73/143 (51.05%), Postives = 101/143 (70.63%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI +KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          

HSP 2 Score: 59.3066 bits (142), Expect = 8.879e-12
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          

HSP 3 Score: 57.7658 bits (138), Expect = 2.694e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149          
BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 142.124 bits (357), Expect = 7.989e-44
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          

HSP 2 Score: 58.5362 bits (140), Expect = 1.440e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          

HSP 3 Score: 58.151 bits (139), Expect = 2.382e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149          
BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 142.124 bits (357), Expect = 1.004e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          

HSP 2 Score: 57.7658 bits (138), Expect = 2.778e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149          

HSP 3 Score: 56.225 bits (134), Expect = 1.052e-10
Identity = 33/74 (44.59%), Postives = 48/74 (64.86%), Query Frame = 3
Query:  312 AEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            A++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    2 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          
BLAST of Centrin-1 vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 164.466 bits (415), Expect = 1.539e-52
Identity = 85/143 (59.44%), Postives = 108/143 (75.52%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            EL EEQKQE+ EAF LFD +  G +D  ELKVAM+ALGFE  K E+  LI +YD EG+ ++++ DF  +M +K+ ++D  +EI +AF+LFDDD TGKIS KNL+RVAKELGE LTDEEL+ MI+E D D DGEINE EF+ I 
Sbjct:   16 ELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAIC 158          
BLAST of Centrin-1 vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 122.865 bits (307), Expect = 1.646e-36
Identity = 64/144 (44.44%), Postives = 94/144 (65.28%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            LTEEQ  E +EAF LFD D +G+I   EL   MR+LG  P + EV  L+ + D++G   IEFS+FL++M++++   D+++E+L+AFK+FD +  G IS   LK V   +GE LTD E+ +M+ E   D  GEIN Q+F  ++ K
Sbjct:    5 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 147          
BLAST of Centrin-1 vs. Ensembl Yeast
Match: MLC1 (Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074])

HSP 1 Score: 67.0106 bits (162), Expect = 7.298e-15
Identity = 43/136 (31.62%), Postives = 76/136 (55.88%), Query Frame = 3
Query:  120 REAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLI-ADYDIEGKGIIEFSDFLSMM--TQKMAEKDTK---EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFL 509
            ++ F LFD  G G I    L   +RA+G+ P  + V+ +I AD  +     +       ++   +K  +  TK   E+ +KAF++FD + TGK+S  +L+ +   LGE LTD E+ E++   + D++GEI+ ++F+
Sbjct:    8 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFI 143          
BLAST of Centrin-1 vs. Ensembl Yeast
Match: CNB1 (Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673])

HSP 1 Score: 52.373 bits (124), Expect = 3.168e-9
Identity = 42/144 (29.17%), Postives = 77/144 (53.47%), Query Frame = 3
Query:  111 QEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAK-ELGENLTDEELQEMID----EADRDNDGEINEQEFLRIMKKT 527
            + +R+ F   D D SG+ID  E  +++  +   P    + ++   +D +  G ++F +F++ ++         E++  AFK++D D+ G IS   L  V K  +G NL DE+LQ+++D    E D D DG ++ +EF   ++ T
Sbjct:   24 ERLRKRFMKLDRDSSGSIDKNEF-MSIPGVSSNPLAGRIMEV---FDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAIETT 163          
BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO40775 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S690])

HSP 1 Score: 259.61 bits (662), Expect = 1.156e-89
Identity = 133/163 (81.60%), Postives = 148/163 (90.80%), Query Frame = 3
Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            G  Q+KK  +G +PELTEEQKQE+REAFDLFD DGSGTID KELKVAMRALGFEPKKEE++K+I+D D +G G I+F++FL MMT KM+EKD+KEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINE EFLRIMKKT+LY
Sbjct:    2 GGGQRKK--TGPKPELTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISDIDKDGSGTIDFNEFLQMMTAKMSEKDSKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEAEFLRIMKKTSLY 162          
BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO44944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU39])

HSP 1 Score: 182.57 bits (462), Expect = 3.889e-59
Identity = 93/153 (60.78%), Postives = 116/153 (75.82%), Query Frame = 3
Query:   60 KKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            K +G    R EL EEQ+QE++EAF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  +MT  M ++D +EE+ KAF+LFDDD++GKIS +NL+RVA+ELGEN+TDEEL+ MIDE D+D DGEINE EFL IM
Sbjct:   12 KNRGSKPKRRELGEEQRQEIKEAFNLFDTDKDQAIDYHELKVAMRALGFDVKKADVLKIMKDYDRESTGKISFDDFNEVMTDWMLDRDPQEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDGDGEINEDEFLAIM 164          
BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 141.354 bits (355), Expect = 3.250e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 146          

HSP 2 Score: 58.151 bits (139), Expect = 3.420e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          

HSP 3 Score: 57.3806 bits (137), Expect = 7.086e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMMTSK 149          
BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO46606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN8])

HSP 1 Score: 132.494 bits (332), Expect = 7.143e-40
Identity = 68/135 (50.37%), Postives = 92/135 (68.15%), Query Frame = 3
Query:  114 EVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM   D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N  EF+++M
Sbjct:    3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKNTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMM 137          

HSP 2 Score: 58.151 bits (139), Expect = 3.119e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPEL---------TEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   44 INEVDADGNGTIDFPEFLTMMARKMKNTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMMTSK 140          

HSP 3 Score: 56.225 bits (134), Expect = 1.666e-10
Identity = 30/64 (46.88%), Postives = 41/64 (64.06%), Query Frame = 3
Query:  333 EILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            E  +AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 66          
BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO30674 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T043])

HSP 1 Score: 133.265 bits (334), Expect = 1.069e-39
Identity = 67/147 (45.58%), Postives = 106/147 (72.11%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTN 530
            ELT EQ+ E++EAF LFD DGSGTI  +EL+V M++LG  P  EE++++I + D +G G ++F +FL+MM ++M  +D + E+ +AF++FD +  G IS   L+ V   LGE L+D+E++EM+ EAD D DG IN QEF++++++ +
Sbjct:   12 ELTAEQRNELQEAFSLFDKDGSGTISNEELEVVMKSLGQNPSDEELQQMIQEVDADGNGEVDFEEFLAMMKKQMQHRDAEAEMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMVREMD 158          
BLAST of Centrin-1 vs. Ensembl Medaka
Match: cetn2 (caltractin [Source:NCBI gene;Acc:101170769])

HSP 1 Score: 247.669 bits (631), Expect = 2.496e-84
Identity = 123/172 (71.51%), Postives = 147/172 (85.47%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            T+ K+ +  G     +  +  + ELTEEQKQE+REAF+LFD DGSG ID+K+LKVAMRALGFEPKKEE++K+I + D +  G I F+DFL++MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N++EFLRIMKKT LY
Sbjct:    4 TTAKRPALQGPVPPPRKKTTPKAELTEEQKQEIREAFELFDTDGSGFIDVKDLKVAMRALGFEPKKEEIKKMIGEVDKDATGKISFADFLTVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQEEFLRIMKKTCLY 175          
BLAST of Centrin-1 vs. Ensembl Medaka
Match: cetn2 (caltractin [Source:NCBI gene;Acc:101170769])

HSP 1 Score: 247.669 bits (631), Expect = 2.496e-84
Identity = 123/172 (71.51%), Postives = 147/172 (85.47%), Query Frame = 3
Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            T+ K+ +  G     +  +  + ELTEEQKQE+REAF+LFD DGSG ID+K+LKVAMRALGFEPKKEE++K+I + D +  G I F+DFL++MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N++EFLRIMKKT LY
Sbjct:    4 TTAKRPALQGPVPPPRKKTTPKAELTEEQKQEIREAFELFDTDGSGFIDVKDLKVAMRALGFEPKKEEIKKMIGEVDKDATGKISFADFLTVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQEEFLRIMKKTCLY 175          
BLAST of Centrin-1 vs. Ensembl Medaka
Match: cetn3 (centrin 3 [Source:NCBI gene;Acc:101165824])

HSP 1 Score: 183.726 bits (465), Expect = 2.893e-59
Identity = 95/155 (61.29%), Postives = 117/155 (75.48%), Query Frame = 3
Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +Q  K     R ELTEEQK EV+EAFDLFD D    ID  ELKVAMRALGFE KK +V K++ DYD +G   I F DF  ++T ++ E+D KEE+LKAFKLFDDDE+G+IS +NL+RVA+ELGE++ DEEL+ MIDE D D DGEIN++EFL IM
Sbjct:    8 DQADKNKPNKRRELTEEQKHEVKEAFDLFDTDKDRQIDYHELKVAMRALGFEVKKMDVLKILKDYDRDGNRKITFEDFSEVVTDRILERDPKEEVLKAFKLFDDDESGRISLRNLRRVARELGEDINDEELRSMIDEFDTDRDGEINQEEFLAIM 162          

HSP 2 Score: 50.0618 bits (118), Expect = 1.244e-7
Identity = 28/70 (40.00%), Postives = 43/70 (61.43%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+EV +AF LFD D SG I ++ L+   R LG +   EE+R +I ++D +  G I   +FL++MT
Sbjct:   94 LERDPKEEVLKAFKLFDDDESGRISLRNLRRVARELGEDINDEELRSMIDEFDTDRDGEINQEEFLAIMT 163          
BLAST of Centrin-1 vs. Ensembl Medaka
Match: calm2a (calmodulin 2 [Source:NCBI gene;Acc:100049420])

HSP 1 Score: 142.124 bits (357), Expect = 3.914e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          

HSP 2 Score: 58.5362 bits (140), Expect = 7.054e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          

HSP 3 Score: 58.151 bits (139), Expect = 1.167e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149          
BLAST of Centrin-1 vs. Ensembl Medaka
Match: ENSORLT00000008599.2 (calmodulin 3 [Source:NCBI gene;Acc:100049421])

HSP 1 Score: 142.124 bits (357), Expect = 3.914e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146          

HSP 2 Score: 58.5362 bits (140), Expect = 7.054e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3
Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75          

HSP 3 Score: 58.151 bits (139), Expect = 1.167e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3
Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149          
BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000015458.1 (SMESG000015458.1)

HSP 1 Score: 306.99 bits (785), Expect = 6.365e-108
Identity = 160/173 (92.49%), Postives = 162/173 (93.64%), Query Frame = 3
Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDET K   K  K+  K +  NLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY
Sbjct:    1 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETEKFLLK-FKKSCKRIRRNLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 172          
BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000052182.1 (SMESG000052182.1)

HSP 1 Score: 228.024 bits (580), Expect = 1.509e-77
Identity = 116/116 (100.00%), Postives = 116/116 (100.00%), Query Frame = 3
Query:  189 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY
Sbjct:    1 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 116          
BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000015458.1 (SMESG000015458.1)

HSP 1 Score: 197.208 bits (500), Expect = 2.248e-65
Identity = 103/116 (88.79%), Postives = 105/116 (90.52%), Query Frame = 3
Query:  189 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDET K   K  K+  K +  NLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY
Sbjct:    1 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETEKFLLK-FKKSCKRIRRNLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 115          
BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000040368.1 (SMESG000040368.1)

HSP 1 Score: 148.288 bits (373), Expect = 8.042e-46
Identity = 72/123 (58.54%), Postives = 102/123 (82.93%), Query Frame = 3
Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMI 458
            EL+E+QK+++++AF+LFD DGSGTIDI+E+KVA+RAL FEP K+++RKLI++YD + KG I+F++FL +++ KM E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQ ++
Sbjct:   13 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQVVL 135          
BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000016538.1 (SMESG000016538.1)

HSP 1 Score: 147.517 bits (371), Expect = 3.867e-45
Identity = 73/143 (51.05%), Postives = 109/143 (76.22%), Query Frame = 3
Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGI-IEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            LT +Q+ E+ EAF+LFD+D  G +   E KV++RALGFE KK +V K+++D++I+     I+F DF  ++++ + E+D   E+++AFKLFDDDE+GKIS++NLK+VA+ELGE LTD E++ MI+E D+D DG IN +EF+ IM
Sbjct:   16 LTVDQRNEINEAFELFDSDKDGLLSQYEFKVSLRALGFEVKKHDVTKILSDFNIKDDAPKIKFDDFNEIVSEMILERDPTTEMIRAFKLFDDDESGKISYRNLKKVARELGETLTDHEIRAMIEEFDKDGDGSINMEEFMAIM 158          
The following BLAST results are available for this feature:
BLAST of Centrin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CETN21.862e-9076.74centrin 2 [Source:HGNC Symbol;Acc:HGNC:1867][more]
CETN18.443e-9077.33centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866][more]
CETN35.451e-5661.38centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868][more]
CETN34.469e-5161.76centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868][more]
CETN37.518e-5161.48centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868][more]
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BLAST of Centrin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cmd-11.085e-4251.05Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
cal-12.581e-3444.14Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cal-15.052e-3444.14Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cal-45.498e-3140.51CALmodulin related genes [Source:UniProtKB/TrEMBL... [more]
cal-45.969e-3140.51CALmodulin related genes [Source:UniProtKB/TrEMBL... [more]
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BLAST of Centrin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG174934.937e-7568.94gene:FBgn0040010 transcript:FBtr0332630[more]
CG174934.937e-7568.94gene:FBgn0040010 transcript:FBtr0332632[more]
CG174934.937e-7568.94gene:FBgn0040010 transcript:FBtr0332631[more]
CG318023.622e-5753.76gene:FBgn0051802 transcript:FBtr0081058[more]
Cam1.552e-4251.05gene:FBgn0000253 transcript:FBtr0304964[more]
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BLAST of Centrin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cetn45.666e-9681.50centrin 4 [Source:ZFIN;Acc:ZDB-GENE-030826-21][more]
cetn29.288e-9076.16centrin, EF-hand protein, 2 [Source:ZFIN;Acc:ZDB-G... [more]
cetn33.286e-5764.14centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152][more]
cetn33.972e-5764.14centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152][more]
calm3a4.647e-4351.05calmodulin 3a (phosphorylase kinase, delta) [Sourc... [more]
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BLAST of Centrin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cetn15.594e-9279.07centrin 1 [Source:NCBI gene;Acc:549903][more]
dtl2.916e-9076.30denticleless E3 ubiquitin protein ligase homolog [... [more]
cetn11.302e-8985.43centrin 1 [Source:NCBI gene;Acc:549903][more]
dtl3.076e-8979.75denticleless E3 ubiquitin protein ligase homolog [... [more]
rab381.538e-5662.76RAB38, member RAS oncogene family [Source:Xenbase;... [more]
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BLAST of Centrin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cetn22.030e-9177.91centrin 2 [Source:MGI Symbol;Acc:MGI:1347085][more]
Cetn22.165e-9086.09centrin 2 [Source:MGI Symbol;Acc:MGI:1347085][more]
Cetn22.165e-9086.09centrin 2 [Source:MGI Symbol;Acc:MGI:1347085][more]
Cetn13.814e-8975.00centrin 1 [Source:MGI Symbol;Acc:MGI:1347086][more]
Cetn13.814e-8975.00centrin 1 [Source:MGI Symbol;Acc:MGI:1347086][more]
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BLAST of Centrin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q32LE3|CETN1_BOVIN8.718e-9480.23Centrin-1 OS=Bos taurus OX=9913 GN=CETN1 PE=2 SV=1[more]
sp|Q2TBN3|CETN2_BOVIN3.940e-9177.33Centrin-2 OS=Bos taurus OX=9913 GN=CETN2 PE=2 SV=1[more]
sp|Q9R1K9|CETN2_MOUSE1.420e-9077.91Centrin-2 OS=Mus musculus OX=10090 GN=Cetn2 PE=1 S... [more]
sp|P41208|CETN2_HUMAN8.942e-9076.74Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV... [more]
sp|Q12798|CETN1_HUMAN4.055e-8977.33Centrin-1 OS=Homo sapiens OX=9606 GN=CETN1 PE=1 SV... [more]
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BLAST of Centrin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A444U7H93.519e-9482.56Centrin-1 OS=Acipenser ruthenus OX=7906 GN=EOD39_1... [more]
F1R7891.268e-9281.50Centrin 4 OS=Danio rerio OX=7955 GN=cetn4 PE=4 SV=... [more]
B1P0R91.580e-9281.50Centrin2 (Fragment) OS=Danio rerio OX=7955 GN=cetn... [more]
A0A4W4F0V63.366e-9281.98Uncharacterized protein OS=Electrophorus electricu... [more]
W5P1654.833e-9280.81Centrin 1 OS=Ovis aries OX=9940 GN=CETN1 PE=4 SV=1[more]
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BLAST of Centrin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cetn42.682e-9481.98caltractin [Source:NCBI gene;Acc:103037928][more]
cetn42.956e-9481.98caltractin [Source:NCBI gene;Acc:103037928][more]
cetn21.570e-8976.16centrin-1 [Source:NCBI gene;Acc:103028142][more]
cetn32.120e-5864.83centrin 3 [Source:NCBI gene;Acc:103024517][more]
calm3a3.938e-4351.05calmodulin [Source:NCBI gene;Acc:103037741][more]
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BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CETN12.170e-9477.09centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866][more]
cetn33.172e-5356.29centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152][more]
ENSPMAT00000006008.12.663e-4451.05pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-... [more]
CALM37.989e-4451.05calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
CALML31.004e-4351.05calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145... [more]
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BLAST of Centrin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
CDC311.539e-5259.44Calcium-binding component of the spindle pole body... [more]
CMD11.646e-3644.44Calmodulin; Ca2+ binding protein that regulates Ca... [more]
MLC17.298e-1531.62Essential light chain for Myo1p; light chain for M... [more]
CNB13.168e-929.17Calcineurin B; regulatory subunit of calcineurin, ... [more]
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BLAST of Centrin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO407751.156e-8981.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449443.889e-5960.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465183.250e-4351.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466067.143e-4050.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306741.069e-3945.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Centrin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cetn22.496e-8471.51caltractin [Source:NCBI gene;Acc:101170769][more]
cetn22.496e-8471.51caltractin [Source:NCBI gene;Acc:101170769][more]
cetn32.893e-5961.29centrin 3 [Source:NCBI gene;Acc:101165824][more]
calm2a3.914e-4351.05calmodulin 2 [Source:NCBI gene;Acc:100049420][more]
ENSORLT00000008599.23.914e-4351.05calmodulin 3 [Source:NCBI gene;Acc:100049421][more]
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BLAST of Centrin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000015458.16.365e-10892.49SMESG000015458.1[more]
SMESG000052182.11.509e-77100.00SMESG000052182.1[more]
SMESG000015458.12.248e-6588.79SMESG000015458.1[more]
SMESG000040368.18.042e-4658.54SMESG000040368.1[more]
SMESG000016538.13.867e-4551.05SMESG000016538.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015945 ID=SMED30015945|Name=Centrin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=599bp
ATCTATATAAATCTTATATGACTAGTCTAAAAAAAGGATCAGCAGGTGGA
ATCAACCAAAAGAAAAAAGGTGGTTCAGGTGATCGCCCAGAATTAACTGA
AGAACAGAAACAAGAAGTTCGAGAGGCTTTTGATTTATTTGATGCTGATG
GCTCAGGAACAATAGATATAAAAGAACTAAAAGTTGCCATGAGGGCTTTA
GGATTTGAACCCAAAAAAGAAGAAGTTCGGAAATTAATAGCTGATTATGA
TATCGAAGGAAAAGGCATCATTGAATTTAGTGATTTTCTTAGTATGATGA
CGCAAAAAATGGCAGAAAAAGATACGAAAGAAGAAATATTAAAAGCATTT
AAATTGTTCGATGATGATGAAACGGGAAAAATTTCTTTTAAAAATTTAAA
AAGAGTTGCAAAAGAATTAGGCGAAAATTTAACAGACGAAGAACTTCAAG
AAATGATTGATGAAGCTGATAGAGATAATGATGGAGAAATTAACGAGCAA
GAATTCTTAAGAATAATGAAGAAAACAAATTTATATTAGTGTTTTGTGTA
ATTATAAAATGAGCTTTGTAATATAATTGAAATTTTCCATTAAAAAAAA
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protein sequence of SMED30015945-orf-1

>SMED30015945-orf-1 ID=SMED30015945-orf-1|Name=SMED30015945-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=179bp
LYKSYMTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADG
SGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT
QKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQE
MIDEADRDNDGEINEQEFLRIMKKTNLY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR037629Centrin_2
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
IPR000629RNA-helicase_DEAD-box_CS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0008017microtubule binding
GO:0031683G-protein beta/gamma-subunit complex binding
GO:0032795heterotrimeric G-protein binding
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0000922spindle pole
GO:0005737cytoplasm
GO:0005813centrosome
GO:0005814centriole
GO:0005815microtubule organizing center
GO:0005856cytoskeleton
GO:0032391photoreceptor connecting cilium
Vocabulary: biological process
TermDefinition
GO:0007049cell cycle
GO:0007067mitotic nuclear division
GO:0034605cellular response to heat
GO:0051301cell division
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002048EF-hand domainSMARTSM00054efh_1coord: 140..168
e-value: 2.0E-8
score: 44.0
coord: 68..96
e-value: 0.0086
score: 25.3
coord: 32..60
e-value: 1.5E-8
score: 44.4
IPR002048EF-hand domainPFAMPF13499EF-hand_7coord: 31..93
e-value: 2.1E-12
score: 47.3
IPR002048EF-hand domainPFAMPF00036EF-hand_1coord: 140..167
e-value: 6.3E-9
score: 34.8
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 136..171
score: 14.458
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 28..63
score: 17.331
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 64..99
score: 11.64
IPR002048EF-hand domainCDDcd00051EFhcoord: 105..166
e-value: 3.04348E-10
score: 51.3945
IPR002048EF-hand domainCDDcd00051EFhcoord: 32..94
e-value: 1.0723E-15
score: 65.6469
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 90..170
e-value: 3.2E-18
score: 67.7
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 23..89
e-value: 1.9E-23
score: 84.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..30
NoneNo IPR availablePANTHERPTHR23050CALCIUM BINDING PROTEINcoord: 17..171
IPR037629Centrin 2PANTHERPTHR23050:SF305CENTRIN-2coord: 17..171
IPR000629ATP-dependent RNA helicase DEAD-box, conserved sitePROSITEPS00039DEAD_ATP_HELICASEcoord: 144..152
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 149..161
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 41..53
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 23..167