Centrin-1

Overview


Name	Centrin-1
Smed ID	SMED30015945
Length (bp)	599

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Centrin-1 (SMED30015945) t-SNE clustered cells

Violin plots show distribution of expression levels for Centrin-1 (SMED30015945) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Centrin-1 (SMED30015945) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Centrin-1 (SMED30015945) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015945

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30015945	SMESG000052182.1 SMESG000015458.1	dd_Smed_v4_3644_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30015945	SMESG000052182.1 SMESG000015458.1	dd_Smed_v4_3644_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30015945	SMESG000052182.1 SMESG000015458.1	dd_Smed_v4_3644_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015945	SMESG000052182.1 SMESG000015458.1	dd_Smed_v4_3644_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30015945	SMESG000052182.1 SMESG000015458.1	dd_Smed_v4_3644_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015945	SMESG000052182.1 SMESG000015458.1	Contig42390	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015945	SMESG000052182.1 SMESG000015458.1	Contig42390	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
head region	SMED30015945	SMESG000052182.1 SMESG000015458.1	dd_Smed_v6_3644_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30015945	SMESG000052182.1 SMESG000015458.1	dd_Smed_v4_3644_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Centrin-1 vs. Ensembl Human
Match: CETN2 (centrin 2 [Source:HGNC Symbol;Acc:HGNC:1867])

HSP 1 Score: 263.848 bits (673), Expect = 1.862e-90
Identity = 132/172 (76.74%), Postives = 154/172 (89.53%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +    +Q+K+     +PELTEEQKQE+REAFDLFDADG+GTID+KELKVAMRALGFEPKKEE++K+I++ D EG G + F DFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE++EQEFLRIMKKT+LY
Sbjct:    3 SNFKKANMASSSQRKRMSP--KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Human
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 262.307 bits (669), Expect = 8.443e-90
Identity = 133/172 (77.33%), Postives = 151/172 (87.79%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +  KK SA    QK+K     +PELTE+QKQEVREAFDLFD DGSGTID KELKVAMRALGFEP+KEE++K+I++ D EG G I F+DFL++MTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGENLTDEELQEMIDEADRD DGE+NE+EFLRIMKKT+LY
Sbjct:    3 SGFKKPSAASTGQKRK--VAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Human
Match: CETN3 (centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868])

HSP 1 Score: 176.407 bits (446), Expect = 5.451e-56
Identity = 89/145 (61.38%), Postives = 115/145 (79.31%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R EL+EEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + E+D  EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN++DEEL+ MI+E D+D DGEIN++EF+ IM
Sbjct:   19 RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIM 163

[Close]

BLAST of Centrin-1 vs. Ensembl Human
Match: CETN3 (centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868])

HSP 1 Score: 164.466 bits (415), Expect = 4.469e-51
Identity = 84/136 (61.76%), Postives = 107/136 (78.68%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEI 491
            R EL+EEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + E+D  EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN++DEEL+ MI+E D+D DGEI
Sbjct:   19 RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEI 154

[Close]

BLAST of Centrin-1 vs. Ensembl Human
Match: CETN3 (centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868])

HSP 1 Score: 162.925 bits (411), Expect = 7.518e-51
Identity = 83/135 (61.48%), Postives = 106/135 (78.52%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGE 488
            R EL+EEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + E+D  EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN++DEEL+ MI+E D+D DGE
Sbjct:   19 RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGE 153

[Close]

BLAST of Centrin-1 vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 140.584 bits (353), Expect = 1.085e-42
Identity = 73/143 (51.05%), Postives = 99/143 (69.23%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+ +M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146

HSP 2 Score: 58.5362 bits (140), Expect = 5.126e-11
Identity = 36/97 (37.11%), Postives = 55/97 (56.70%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F++MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTTK 149

HSP 3 Score: 58.5362 bits (140), Expect = 5.508e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

[Close]

BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 119.783 bits (299), Expect = 2.581e-34
Identity = 64/145 (44.14%), Postives = 95/145 (65.52%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            +LT E+  E REAF +FD DG+GTI  KEL +AMR+LG  P ++E+ ++I + DI+G G IEF +F  MM + M E D+ E I +AF++FD D  G I+ +  +     +G   ++EE+ EMI E D D DGEI+ +EF+++M  
Sbjct:   17 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMKETDS-EMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSN 160

HSP 2 Score: 53.9138 bits (128), Expect = 3.339e-9
Identity = 25/72 (34.72%), Postives = 46/72 (63.89%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            + E   + +REAF +FD DG+G I  +E +  M  +G +  +EEV ++I + D++G G I++ +F+ MM+ +
Sbjct:   90 MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 161

[Close]

BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 119.398 bits (298), Expect = 5.052e-34
Identity = 64/145 (44.14%), Postives = 95/145 (65.52%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            +LT E+  E REAF +FD DG+GTI  KEL +AMR+LG  P ++E+ ++I + DI+G G IEF +F  MM + M E D+ E I +AF++FD D  G I+ +  +     +G   ++EE+ EMI E D D DGEI+ +EF+++M  
Sbjct:   36 QLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGNGQIEFPEFCVMMKRMMKETDS-EMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSN 179

HSP 2 Score: 53.9138 bits (128), Expect = 5.196e-9
Identity = 25/72 (34.72%), Postives = 46/72 (63.89%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            + E   + +REAF +FD DG+G I  +E +  M  +G +  +EEV ++I + D++G G I++ +F+ MM+ +
Sbjct:  109 MKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMMSNQ 180

[Close]

BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-4 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:G5EDZ8])

HSP 1 Score: 111.694 bits (278), Expect = 5.498e-31
Identity = 64/158 (40.51%), Postives = 97/158 (61.39%), Query Frame = 3

Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILK-AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            G NQ       D  E T E+ QE  +AF LFD DG+ T++IKEL  AMR LG  P +EE+  ++ +YD++G G I+F +F  MM  K   K+T +E+++ AFK+FD D  G I+ +  K     +GE  ++EE+ E+I E D+D D +I+  EF+ ++
Sbjct:    5 GTNQSV---CSDADEFTPEELQEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMM--KEMNKETDQELIRLAFKVFDKDGNGYITAQEFKHFMTTMGERFSEEEVDEIIREVDKDGDEQIDLDEFVNMV 157

HSP 2 Score: 51.6026 bits (122), Expect = 2.824e-8
Identity = 28/67 (41.79%), Postives = 42/67 (62.69%), Query Frame = 3

Query:  330 EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTN 530
            +E  +AFKLFD D    ++ K L    + LG N T+EEL  M++E D D +G+I+  EF ++MK+ N
Sbjct:   23 QEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMMKEMN 89

[Close]

BLAST of Centrin-1 vs. Ensembl Celegans
Match: cal-4 (CALmodulin related genes [Source:UniProtKB/TrEMBL;Acc:G5EDZ8])

HSP 1 Score: 112.464 bits (280), Expect = 5.969e-31
Identity = 64/158 (40.51%), Postives = 97/158 (61.39%), Query Frame = 3

Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILK-AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            G NQ       D  E T E+ QE  +AF LFD DG+ T++IKEL  AMR LG  P +EE+  ++ +YD++G G I+F +F  MM  K   K+T +E+++ AFK+FD D  G I+ +  K     +GE  ++EE+ E+I E D+D D +I+  EF+ ++
Sbjct:   31 GTNQSV---CSDADEFTPEELQEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMM--KEMNKETDQELIRLAFKVFDKDGNGYITAQEFKHFMTTMGERFSEEEVDEIIREVDKDGDEQIDLDEFVNMV 183

HSP 2 Score: 52.373 bits (124), Expect = 2.283e-8
Identity = 28/67 (41.79%), Postives = 42/67 (62.69%), Query Frame = 3

Query:  330 EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTN 530
            +E  +AFKLFD D    ++ K L    + LG N T+EEL  M++E D D +G+I+  EF ++MK+ N
Sbjct:   49 QEFAQAFKLFDKDGNNTMNIKELGEAMRMLGLNPTEEELLNMVNEYDVDGNGKIDFGEFCKMMKEMN 115

[Close]

BLAST of Centrin-1 vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332630)

HSP 1 Score: 224.172 bits (570), Expect = 4.937e-75
Identity = 111/161 (68.94%), Postives = 140/161 (86.96%), Query Frame = 3

Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
             Q+ +  SG + EL+E QK +++EAFDLFD +G+G I++KELKVA+RALGFEPKKEE++++I+D D +  G I F+ FL +MT KMAEKDTKEEILKAF+LFDDD+TGKISF+NLKRVA+ELGE LTDEEL+EMIDEAD DNDGE+N++EFLRIMKKT+LY
Sbjct:   22 TQQGRKKSGPKFELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182

[Close]

BLAST of Centrin-1 vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332632)

HSP 1 Score: 224.172 bits (570), Expect = 4.937e-75
Identity = 111/161 (68.94%), Postives = 140/161 (86.96%), Query Frame = 3

Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
             Q+ +  SG + EL+E QK +++EAFDLFD +G+G I++KELKVA+RALGFEPKKEE++++I+D D +  G I F+ FL +MT KMAEKDTKEEILKAF+LFDDD+TGKISF+NLKRVA+ELGE LTDEEL+EMIDEAD DNDGE+N++EFLRIMKKT+LY
Sbjct:   22 TQQGRKKSGPKFELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182

[Close]

BLAST of Centrin-1 vs. Ensembl Fly
Match: CG17493 (gene:FBgn0040010 transcript:FBtr0332631)

HSP 1 Score: 224.172 bits (570), Expect = 4.937e-75
Identity = 111/161 (68.94%), Postives = 140/161 (86.96%), Query Frame = 3

Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
             Q+ +  SG + EL+E QK +++EAFDLFD +G+G I++KELKVA+RALGFEPKKEE++++I+D D +  G I F+ FL +MT KMAEKDTKEEILKAF+LFDDD+TGKISF+NLKRVA+ELGE LTDEEL+EMIDEAD DNDGE+N++EFLRIMKKT+LY
Sbjct:   22 TQQGRKKSGPKFELSEAQKCDIKEAFDLFDNEGTGYIEVKELKVAIRALGFEPKKEEIKRMISDIDKDCSGRIAFNVFLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTDEELREMIDEADLDNDGEVNQEEFLRIMKKTSLY 182

[Close]

BLAST of Centrin-1 vs. Ensembl Fly
Match: CG31802 (gene:FBgn0051802 transcript:FBtr0081058)

HSP 1 Score: 179.104 bits (453), Expect = 3.622e-57
Identity = 93/173 (53.76%), Postives = 128/173 (73.99%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRP--ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNL 533
             S+   SA   ++ KK      P  +L+  QK ++++AFDLFD   +G I+ KEL+VA+RALGFEPKKE++++++ + D +  G I F+DFL +M  KMAEKD+ ++++KAF  FDDD TG ISF NLKRVAKELGE LTDEELQEMIDEA+   DGE++++EFL ++KKTNL
Sbjct:   13 ASVMHSSASISSRAKKSKKPKLPTFDLSLSQKVDIKKAFDLFDTQCTGFIETKELRVAIRALGFEPKKEDIKRMMDEIDKDKTGRIAFNDFLYLMRLKMAEKDSNQDMMKAFSFFDDDRTGGISFLNLKRVAKELGEQLTDEELQEMIDEANVSGDGEVSKEEFLNLIKKTNL 185

[Close]

BLAST of Centrin-1 vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 140.584 bits (353), Expect = 1.552e-42
Identity = 73/143 (51.05%), Postives = 99/143 (69.23%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+ +M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146

HSP 2 Score: 58.5362 bits (140), Expect = 6.243e-11
Identity = 36/97 (37.11%), Postives = 55/97 (56.70%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F++MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 149

HSP 3 Score: 58.5362 bits (140), Expect = 7.062e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

[Close]

BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn4 (centrin 4 [Source:ZFIN;Acc:ZDB-GENE-030826-21])

HSP 1 Score: 277.33 bits (708), Expect = 5.666e-96
Identity = 141/173 (81.50%), Postives = 155/173 (89.60%), Query Frame = 3

Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S  + S+   NQ+KK G   +PELTEEQKQE++EAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G+I FSDFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    1 MASGFRKSSASANQRKKAGP--KPELTEEQKQEIKEAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGVIGFSDFLSMMTQKMSEKDSKEEILKAFRLFDDDCTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171

[Close]

BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn2 (centrin, EF-hand protein, 2 [Source:ZFIN;Acc:ZDB-GENE-091118-94])

HSP 1 Score: 261.536 bits (667), Expect = 9.288e-90
Identity = 131/172 (76.16%), Postives = 151/172 (87.79%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            TS K+ S G +  +KK     + ELTEEQKQE+REAF+LFD DGSG I++KELKVAMRALGFEPKKEE++K+IA+ D E  G I F+DFLS+MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N+QEFLRIMKKT+LY
Sbjct:    3 TSPKRPSLGAVAPRKKASP--KSELTEEQKQEIREAFELFDTDGSGYIEVKELKVAMRALGFEPKKEEIKKMIAEVDKEATGKISFTDFLSVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQQEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn3 (centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152])

HSP 1 Score: 178.718 bits (452), Expect = 3.286e-57
Identity = 93/145 (64.14%), Postives = 114/145 (78.62%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELT+EQK E++EAF+LFD D    ID  ELKVAMRALGFE KK +V K++ DYD EG G I F DF  ++T  + E+D KEEILKAFKLFDDDETGKIS +NL+RVA+ELGE+++DE+L+ MIDE D D DGEIN+ EF+ IM
Sbjct:   19 RRELTDEQKDEIKEAFELFDTDKDKEIDYHELKVAMRALGFEVKKVDVLKILKDYDREGTGKISFEDFREVVTDMILERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIM 163

HSP 2 Score: 49.6766 bits (117), Expect = 2.392e-7
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+E+ +AF LFD D +G I ++ L+   R LG +   E++R +I ++D +G G I   +F+S+MT
Sbjct:   95 LERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIMT 164

[Close]

BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: cetn3 (centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152])

HSP 1 Score: 178.333 bits (451), Expect = 3.972e-57
Identity = 93/145 (64.14%), Postives = 114/145 (78.62%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELT+EQK E++EAF+LFD D    ID  ELKVAMRALGFE KK +V K++ DYD EG G I F DF  ++T  + E+D KEEILKAFKLFDDDETGKIS +NL+RVA+ELGE+++DE+L+ MIDE D D DGEIN+ EF+ IM
Sbjct:   15 RRELTDEQKDEIKEAFELFDTDKDKEIDYHELKVAMRALGFEVKKVDVLKILKDYDREGTGKISFEDFREVVTDMILERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIM 159

HSP 2 Score: 49.6766 bits (117), Expect = 2.175e-7
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+E+ +AF LFD D +G I ++ L+   R LG +   E++R +I ++D +G G I   +F+S+MT
Sbjct:   91 LERDPKEEILKAFKLFDDDETGKISLRNLRRVARELGEDMSDEDLRAMIDEFDTDGDGEINQDEFISIMT 160

[Close]

BLAST of Centrin-1 vs. Ensembl Zebrafish
Match: calm3a (calmodulin 3a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-5590])

HSP 1 Score: 142.124 bits (357), Expect = 4.647e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 58.5362 bits (140), Expect = 8.375e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 58.151 bits (139), Expect = 1.385e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149

[Close]

BLAST of Centrin-1 vs. Ensembl Xenopus
Match: cetn1 (centrin 1 [Source:NCBI gene;Acc:549903])

HSP 1 Score: 267.7 bits (683), Expect = 5.594e-92
Identity = 136/172 (79.07%), Postives = 152/172 (88.37%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK S G   Q+KK     +PELTEEQKQE+REAFDLFD DG+GTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F DF+S MTQKMAEKD+KEEI+KAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNYKKPSLGVTTQRKKPVP--KPELTEEQKQEIREAFDLFDTDGAGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGTGKISFGDFMSAMTQKMAEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Xenopus
Match: dtl (denticleless E3 ubiquitin protein ligase homolog [Source:Xenbase;Acc:XB-GENE-985623])

HSP 1 Score: 263.077 bits (671), Expect = 2.916e-90
Identity = 132/173 (76.30%), Postives = 154/173 (89.02%), Query Frame = 3

Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S+ +    G  Q+++ G+  +PELTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+I+D D +G GII+F DFLS+MTQKM+EKD+KEEI+KAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIM+KT+L 
Sbjct:    1 MASVLRKPGLGATQRRRIGA--KPELTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEMKKIISDTDKDGSGIIDFEDFLSLMTQKMSEKDSKEEIMKAFRLFDDDNTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMRKTSLC 171

[Close]

BLAST of Centrin-1 vs. Ensembl Xenopus
Match: cetn1 (centrin 1 [Source:NCBI gene;Acc:549903])

HSP 1 Score: 261.151 bits (666), Expect = 1.302e-89
Identity = 129/151 (85.43%), Postives = 142/151 (94.04%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +PELTEEQKQE+REAFDLFD DG+GTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F DF+S MTQKMAEKD+KEEI+KAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    7 KPELTEEQKQEIREAFDLFDTDGAGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGTGKISFGDFMSAMTQKMAEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 157

[Close]

BLAST of Centrin-1 vs. Ensembl Xenopus
Match: dtl (denticleless E3 ubiquitin protein ligase homolog [Source:Xenbase;Acc:XB-GENE-985623])

HSP 1 Score: 260.766 bits (665), Expect = 3.076e-89
Identity = 130/163 (79.75%), Postives = 150/163 (92.02%), Query Frame = 3

Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            G  Q+++ G+  +PELTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+I+D D +G GII+F DFLS+MTQKM+EKD+KEEI+KAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIM+KT+L 
Sbjct:   12 GATQRRRIGA--KPELTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEMKKIISDTDKDGSGIIDFEDFLSLMTQKMSEKDSKEEIMKAFRLFDDDNTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMRKTSLC 172

[Close]

BLAST of Centrin-1 vs. Ensembl Xenopus
Match: rab38 (RAB38, member RAS oncogene family [Source:Xenbase;Acc:XB-GENE-480756])

HSP 1 Score: 177.563 bits (449), Expect = 1.538e-56
Identity = 91/145 (62.76%), Postives = 116/145 (80.00%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELTEEQKQE+++AF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  ++T  + ++D +EEILKAFKLFDDD++GKIS +NL+RVA+ELGEN+TDEEL+ MI+E D+D DGEIN++EFL IM
Sbjct:   19 RRELTEEQKQEIKDAFELFDTDKDKAIDYHELKVAMRALGFDVKKADVLKILKDYDGETTGKITFDDFNEVVTDLILDRDPQEEILKAFKLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIEEFDKDGDGEINQEEFLSIM 163

[Close]

BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 265.774 bits (678), Expect = 2.030e-91
Identity = 134/172 (77.91%), Postives = 154/172 (89.53%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +     Q+K+     +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNFKKTTMASSAQRKRMSP--KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn2 (centrin 2 [Source:MGI Symbol;Acc:MGI:1347085])

HSP 1 Score: 262.692 bits (670), Expect = 2.165e-90
Identity = 130/151 (86.09%), Postives = 145/151 (96.03%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:   13 KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 163

[Close]

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:   13 KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 163

[Close]

BLAST of Centrin-1 vs. Ensembl Mouse
Match: Cetn1 (centrin 1 [Source:MGI Symbol;Acc:MGI:1347086])

HSP 1 Score: 259.996 bits (663), Expect = 3.814e-89
Identity = 129/172 (75.00%), Postives = 153/172 (88.95%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ +K +    + K+K G   +PELTE+QKQEVREAFDLFD+DGSGTID+KELKVAMRALGFEP+KEE++K+I++ D E  G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEMIDEADRD DGE+NE+EFL+IMKKTNLY
Sbjct:    3 STFRKSNVASTSYKRKVGP--KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172

[Close]

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ +K +    + K+K G   +PELTE+QKQEVREAFDLFD+DGSGTID+KELKVAMRALGFEP+KEE++K+I++ D E  G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEMIDEADRD DGE+NE+EFL+IMKKTNLY
Sbjct:    3 STFRKSNVASTSYKRKVGP--KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172

[Close]

BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q32LE3|CETN1_BOVIN (Centrin-1 OS=Bos taurus OX=9913 GN=CETN1 PE=2 SV=1)

HSP 1 Score: 273.863 bits (699), Expect = 8.718e-94
Identity = 138/172 (80.23%), Postives = 155/172 (90.12%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K +    +QK+K G   +PELTEEQKQEVREAFDLFDADGSGTID+KELKVAMRALGFEP+KEE++++IAD D EG G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NE EFLRIMKKTNLY
Sbjct:    3 SSYRKPTVASTSQKRKVGP--KPELTEEQKQEVREAFDLFDADGSGTIDVKELKVAMRALGFEPRKEEMKRMIADVDKEGTGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEDEFLRIMKKTNLY 172

[Close]

BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q2TBN3|CETN2_BOVIN (Centrin-2 OS=Bos taurus OX=9913 GN=CETN2 PE=2 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 3.940e-91
Identity = 133/172 (77.33%), Postives = 154/172 (89.53%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +     Q+K+     +PELTEEQKQE+REAFDLFDADG+GTID+KELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENL+DEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNFKKANMASTTQRKRMSP--KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLSDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q9R1K9|CETN2_MOUSE (Centrin-2 OS=Mus musculus OX=10090 GN=Cetn2 PE=1 SV=1)

HSP 1 Score: 265.774 bits (678), Expect = 1.420e-90
Identity = 134/172 (77.91%), Postives = 154/172 (89.53%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +     Q+K+     +PELTE+QKQE+REAFDLFDADG+GTIDIKELKVAMRALGFEPKKEE++K+I++ D EG G + FSDFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NEQEFLRIMKKT+LY
Sbjct:    3 SNFKKTTMASSAQRKRMSP--KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|P41208|CETN2_HUMAN (Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1)

HSP 1 Score: 263.848 bits (673), Expect = 8.942e-90
Identity = 132/172 (76.74%), Postives = 154/172 (89.53%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            ++ KK +    +Q+K+     +PELTEEQKQE+REAFDLFDADG+GTID+KELKVAMRALGFEPKKEE++K+I++ D EG G + F DFL++MTQKM+EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE++EQEFLRIMKKT+LY
Sbjct:    3 SNFKKANMASSSQRKRMSP--KPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172

[Close]

BLAST of Centrin-1 vs. UniProt/SwissProt
Match: sp|Q12798|CETN1_HUMAN (Centrin-1 OS=Homo sapiens OX=9606 GN=CETN1 PE=1 SV=1)

HSP 1 Score: 262.307 bits (669), Expect = 4.055e-89
Identity = 133/172 (77.33%), Postives = 151/172 (87.79%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +  KK SA    QK+K     +PELTE+QKQEVREAFDLFD DGSGTID KELKVAMRALGFEP+KEE++K+I++ D EG G I F+DFL++MTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGENLTDEELQEMIDEADRD DGE+NE+EFLRIMKKT+LY
Sbjct:    3 SGFKKPSAASTGQKRK--VAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY 172

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BLAST of Centrin-1 vs. TrEMBL
Match: A0A444U7H9 (Centrin-1 OS=Acipenser ruthenus OX=7906 GN=EOD39_1794 PE=4 SV=1)

HSP 1 Score: 281.567 bits (719), Expect = 3.519e-94
Identity = 142/172 (82.56%), Postives = 158/172 (91.86%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            TS +K  A G NQ++K G+G++PEL EEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I+F+DFLSMMTQKM+EKDTKEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKT+LY
Sbjct:   16 TSYRK-PAFGPNQRRKPGTGNKPELAEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADVDKEGSGTIDFNDFLSMMTQKMSEKDTKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTSLY 186

[Close]

BLAST of Centrin-1 vs. TrEMBL
Match: F1R789 (Centrin 4 OS=Danio rerio OX=7955 GN=cetn4 PE=4 SV=1)

HSP 1 Score: 277.33 bits (708), Expect = 1.268e-92
Identity = 141/173 (81.50%), Postives = 155/173 (89.60%), Query Frame = 3

Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S  + S+   NQ+KK G   +PELTEEQKQE++EAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G+I FSDFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    1 MASGFRKSSASANQRKKAGP--KPELTEEQKQEIKEAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGVIGFSDFLSMMTQKMSEKDSKEEILKAFRLFDDDCTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171

[Close]

BLAST of Centrin-1 vs. TrEMBL
Match: B1P0R9 (Centrin2 (Fragment) OS=Danio rerio OX=7955 GN=cetn4 PE=2 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 1.580e-92
Identity = 141/173 (81.50%), Postives = 155/173 (89.60%), Query Frame = 3

Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            M S  + S+   NQ+KK G   +PELTEEQKQE++EAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G+I FSDFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    1 MASGFRKSSASANQRKKAGP--KPELTEEQKQEIKEAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGVIGFSDFLSMMTQKMSEKDSKEEILKAFRLFDDDCTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171

[Close]

BLAST of Centrin-1 vs. TrEMBL
Match: A0A4W4F0V6 (Uncharacterized protein OS=Electrophorus electricus OX=8005 GN=LOC113577166 PE=4 SV=1)

HSP 1 Score: 276.174 bits (705), Expect = 3.366e-92
Identity = 141/172 (81.98%), Postives = 157/172 (91.28%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K SA  +NQ+KK G   +P+LTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I+F+DFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    4 SSFRKPSAT-LNQRKKAGP--KPDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTIDFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 172

[Close]

BLAST of Centrin-1 vs. TrEMBL
Match: W5P165 (Centrin 1 OS=Ovis aries OX=9940 GN=CETN1 PE=4 SV=1)

HSP 1 Score: 275.789 bits (704), Expect = 4.833e-92
Identity = 139/172 (80.81%), Postives = 155/172 (90.12%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S KK +    +QK+K G   +PELTEEQKQEVREAFDLFDADGSGTID+KELKVAMRALGFEP+KEE++++IAD D EG G I F+DFL++MTQKMAEKDTKEEILKAF+LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGE+NE EFLRIMKKTNLY
Sbjct:    3 SSFKKSTVASTSQKRKVGP--KPELTEEQKQEVREAFDLFDADGSGTIDVKELKVAMRALGFEPRKEEMKRMIADVDKEGTGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEDEFLRIMKKTNLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn4 (caltractin [Source:NCBI gene;Acc:103037928])

HSP 1 Score: 272.707 bits (696), Expect = 2.682e-94
Identity = 141/172 (81.98%), Postives = 155/172 (90.12%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K SA   NQ+KKGG   + +LTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F+DFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    4 SSFRKPSATA-NQRKKGGP--KVDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTINFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn4 (caltractin [Source:NCBI gene;Acc:103037928])

HSP 1 Score: 272.707 bits (696), Expect = 2.956e-94
Identity = 141/172 (81.98%), Postives = 155/172 (90.12%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            +S +K SA   NQ+KKGG   + +LTEEQKQE+REAFDLFD DGSGTID+KELKVAMRALGFEPKKEE++K+IAD D EG G I F+DFLSMMTQKM+EKD+KEEILKAF+LFDDD TGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINEQEFLRIMKKTNLY
Sbjct:    3 SSFRKPSATA-NQRKKGGP--KVDLTEEQKQEIREAFDLFDTDGSGTIDVKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTINFNDFLSMMTQKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEQEFLRIMKKTNLY 171

[Close]

BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn2 (centrin-1 [Source:NCBI gene;Acc:103028142])

HSP 1 Score: 260.766 bits (665), Expect = 1.570e-89
Identity = 131/172 (76.16%), Postives = 151/172 (87.79%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            TS K+ S G    +KK  +  +PELTEE KQE+REAF+LFD DGSG I++KELKVAMRALGFEPKKEE++K+IAD D +G G I F+DFL++MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N+QEFLRIMKKT LY
Sbjct:    3 TSAKRPSLGAAAPRKK--TSPKPELTEEMKQEIREAFELFDTDGSGHIEVKELKVAMRALGFEPKKEEIKKMIADVDKDGTGKISFNDFLTIMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQQEFLRIMKKTCLY 172

[Close]

BLAST of Centrin-1 vs. Ensembl Cavefish
Match: cetn3 (centrin 3 [Source:NCBI gene;Acc:103024517])

HSP 1 Score: 181.8 bits (460), Expect = 2.120e-58
Identity = 94/145 (64.83%), Postives = 116/145 (80.00%), Query Frame = 3

Query:   84 RPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            R ELTEEQK E++EAF+LFD D    ID  ELKVAMRALGFE KK +V K++ DYD EG G I F DF  ++T ++ E+D KEEILKAFKLFDDDE+GKIS +NL+RVA+ELGE+++DEEL+ MIDE D D DGEIN++EF+ IM
Sbjct:   19 RRELTEEQKDEIKEAFELFDTDKDKEIDYHELKVAMRALGFEVKKVDVLKILKDYDREGTGKITFEDFREVVTDRILERDPKEEILKAFKLFDDDESGKISLRNLRRVARELGEDMSDEELRAMIDEFDTDGDGEINQEEFVSIM 163

HSP 2 Score: 51.6026 bits (122), Expect = 3.945e-8
Identity = 28/70 (40.00%), Postives = 44/70 (62.86%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+E+ +AF LFD D SG I ++ L+   R LG +   EE+R +I ++D +G G I   +F+S+MT
Sbjct:   95 LERDPKEEILKAFKLFDDDESGKISLRNLRRVARELGEDMSDEELRAMIDEFDTDGDGEINQEEFVSIMT 164

[Close]

BLAST of Centrin-1 vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 142.124 bits (357), Expect = 3.938e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 58.5362 bits (140), Expect = 7.098e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 58.151 bits (139), Expect = 1.174e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149

[Close]

BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: CETN1 (centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866])

HSP 1 Score: 271.552 bits (693), Expect = 2.170e-94
Identity = 138/179 (77.09%), Postives = 159/179 (88.83%), Query Frame = 3

Query:    3 LYKSYMTSLKK-GSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            L  S  T  +K G AGG  +KK   SG +PEL+EEQKQE++EAFDLFDADGSGTID+KELKVAMRALGFEPKKEE++K+IAD+D +G G I F+DFL+MMTQKM+EKD++EEILKAF+LFDDDETGKISFKNLKRVAKELGE LTDEELQEMIDEADRD DGEINE+EFLR+MKKT+LY
Sbjct:    8 LLSSQATGFRKLGGAGGAQRKK---SGPKPELSEEQKQEIKEAFDLFDADGSGTIDVKELKVAMRALGFEPKKEEIKKMIADFDKDGSGKINFNDFLAMMTQKMSEKDSREEILKAFRLFDDDETGKISFKNLKRVAKELGETLTDEELQEMIDEADRDGDGEINEEEFLRVMKKTSLY 183

[Close]

BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: cetn3 (centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152])

HSP 1 Score: 166.777 bits (421), Expect = 3.172e-53
Identity = 85/151 (56.29%), Postives = 115/151 (76.16%), Query Frame = 3

Query:   66 KGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            KG    R E+TEEQKQE++EAF+LFD D  G ID  ELKVA+RALGFE  K +V K++ DYD E  G I + DF  +MT+++ E+D  +E+LKAF+LFD+ E+G+I  ++L+RVA+ELGE ++DEEL+ MIDE D D DGEIN++EF+ IM
Sbjct:   14 KGKRRRRREMTEEQKQEIQEAFELFDTDKDGAIDYHELKVAIRALGFEVSKADVIKIMKDYDREDTGKISYDDFCEVMTERVLERDPLDEVLKAFRLFDEGESGRIGVRDLRRVARELGETVSDEELRAMIDEFDTDGDGEINQEEFIAIM 164

[Close]

BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006008.1 (pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-1 gene:ENSPMAG00000005430.1 transcript:ENSPMAT00000006008.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 143.28 bits (360), Expect = 2.663e-44
Identity = 73/143 (51.05%), Postives = 101/143 (70.63%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI +KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 59.3066 bits (142), Expect = 8.879e-12
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 57.7658 bits (138), Expect = 2.694e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149

[Close]

BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 142.124 bits (357), Expect = 7.989e-44
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 58.5362 bits (140), Expect = 1.440e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 58.151 bits (139), Expect = 2.382e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149

[Close]

BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 142.124 bits (357), Expect = 1.004e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 57.7658 bits (138), Expect = 2.778e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149

HSP 3 Score: 56.225 bits (134), Expect = 1.052e-10
Identity = 33/74 (44.59%), Postives = 48/74 (64.86%), Query Frame = 3

Query:  312 AEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            A++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    2 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

[Close]

BLAST of Centrin-1 vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 164.466 bits (415), Expect = 1.539e-52
Identity = 85/143 (59.44%), Postives = 108/143 (75.52%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            EL EEQKQE+ EAF LFD +  G +D  ELKVAM+ALGFE  K E+  LI +YD EG+ ++++ DF  +M +K+ ++D  +EI +AF+LFDDD TGKIS KNL+RVAKELGE LTDEEL+ MI+E D D DGEINE EF+ I 
Sbjct:   16 ELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAIC 158

[Close]

BLAST of Centrin-1 vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 122.865 bits (307), Expect = 1.646e-36
Identity = 64/144 (44.44%), Postives = 94/144 (65.28%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            LTEEQ  E +EAF LFD D +G+I   EL   MR+LG  P + EV  L+ + D++G   IEFS+FL++M++++   D+++E+L+AFK+FD +  G IS   LK V   +GE LTD E+ +M+ E   D  GEIN Q+F  ++ K
Sbjct:    5 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 147

[Close]

BLAST of Centrin-1 vs. Ensembl Yeast
Match: MLC1 (Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074])

HSP 1 Score: 67.0106 bits (162), Expect = 7.298e-15
Identity = 43/136 (31.62%), Postives = 76/136 (55.88%), Query Frame = 3

Query:  120 REAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLI-ADYDIEGKGIIEFSDFLSMM--TQKMAEKDTK---EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFL 509
            ++ F LFD  G G I    L   +RA+G+ P  + V+ +I AD  +     +       ++   +K  +  TK   E+ +KAF++FD + TGK+S  +L+ +   LGE LTD E+ E++   + D++GEI+ ++F+
Sbjct:    8 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFI 143

[Close]

BLAST of Centrin-1 vs. Ensembl Yeast
Match: CNB1 (Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673])

HSP 1 Score: 52.373 bits (124), Expect = 3.168e-9
Identity = 42/144 (29.17%), Postives = 77/144 (53.47%), Query Frame = 3

Query:  111 QEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAK-ELGENLTDEELQEMID----EADRDNDGEINEQEFLRIMKKT 527
            + +R+ F   D D SG+ID  E  +++  +   P    + ++   +D +  G ++F +F++ ++         E++  AFK++D D+ G IS   L  V K  +G NL DE+LQ+++D    E D D DG ++ +EF   ++ T
Sbjct:   24 ERLRKRFMKLDRDSSGSIDKNEF-MSIPGVSSNPLAGRIMEV---FDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAIETT 163

[Close]

BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO40775 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S690])

HSP 1 Score: 259.61 bits (662), Expect = 1.156e-89
Identity = 133/163 (81.60%), Postives = 148/163 (90.80%), Query Frame = 3

Query:   48 GINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            G  Q+KK  +G +PELTEEQKQE+REAFDLFD DGSGTID KELKVAMRALGFEPKKEE++K+I+D D +G G I+F++FL MMT KM+EKD+KEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD DGEINE EFLRIMKKT+LY
Sbjct:    2 GGGQRKK--TGPKPELTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISDIDKDGSGTIDFNEFLQMMTAKMSEKDSKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEINEAEFLRIMKKTSLY 162

[Close]

BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO44944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU39])

HSP 1 Score: 182.57 bits (462), Expect = 3.889e-59
Identity = 93/153 (60.78%), Postives = 116/153 (75.82%), Query Frame = 3

Query:   60 KKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            K +G    R EL EEQ+QE++EAF+LFD D    ID  ELKVAMRALGF+ KK +V K++ DYD E  G I F DF  +MT  M ++D +EE+ KAF+LFDDD++GKIS +NL+RVA+ELGEN+TDEEL+ MIDE D+D DGEINE EFL IM
Sbjct:   12 KNRGSKPKRRELGEEQRQEIKEAFNLFDTDKDQAIDYHELKVAMRALGFDVKKADVLKIMKDYDRESTGKISFDDFNEVMTDWMLDRDPQEEVFKAFRLFDDDDSGKISLRNLRRVARELGENMTDEELRAMIDEFDKDGDGEINEDEFLAIM 164

[Close]

BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 141.354 bits (355), Expect = 3.250e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 146

HSP 2 Score: 58.151 bits (139), Expect = 3.420e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 57.3806 bits (137), Expect = 7.086e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMMTSK 149

[Close]

BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO46606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN8])

HSP 1 Score: 132.494 bits (332), Expect = 7.143e-40
Identity = 68/135 (50.37%), Postives = 92/135 (68.15%), Query Frame = 3

Query:  114 EVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM   D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N  EF+++M
Sbjct:    3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKNTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMM 137

HSP 2 Score: 58.151 bits (139), Expect = 3.119e-11
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPEL---------TEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   44 INEVDADGNGTIDFPEFLTMMARKMKNTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMMTSK 140

HSP 3 Score: 56.225 bits (134), Expect = 1.666e-10
Identity = 30/64 (46.88%), Postives = 41/64 (64.06%), Query Frame = 3

Query:  333 EILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            E  +AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 66

[Close]

BLAST of Centrin-1 vs. Ensembl Nematostella
Match: EDO30674 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T043])

HSP 1 Score: 133.265 bits (334), Expect = 1.069e-39
Identity = 67/147 (45.58%), Postives = 106/147 (72.11%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTN 530
            ELT EQ+ E++EAF LFD DGSGTI  +EL+V M++LG  P  EE++++I + D +G G ++F +FL+MM ++M  +D + E+ +AF++FD +  G IS   L+ V   LGE L+D+E++EM+ EAD D DG IN QEF++++++ +
Sbjct:   12 ELTAEQRNELQEAFSLFDKDGSGTISNEELEVVMKSLGQNPSDEELQQMIQEVDADGNGEVDFEEFLAMMKKQMQHRDAEAEMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMVREMD 158

[Close]

BLAST of Centrin-1 vs. Ensembl Medaka
Match: cetn2 (caltractin [Source:NCBI gene;Acc:101170769])

HSP 1 Score: 247.669 bits (631), Expect = 2.496e-84
Identity = 123/172 (71.51%), Postives = 147/172 (85.47%), Query Frame = 3

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            T+ K+ +  G     +  +  + ELTEEQKQE+REAF+LFD DGSG ID+K+LKVAMRALGFEPKKEE++K+I + D +  G I F+DFL++MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N++EFLRIMKKT LY
Sbjct:    4 TTAKRPALQGPVPPPRKKTTPKAELTEEQKQEIREAFELFDTDGSGFIDVKDLKVAMRALGFEPKKEEIKKMIGEVDKDATGKISFADFLTVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQEEFLRIMKKTCLY 175

[Close]

Query:   21 TSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            T+ K+ +  G     +  +  + ELTEEQKQE+REAF+LFD DGSG ID+K+LKVAMRALGFEPKKEE++K+I + D +  G I F+DFL++MTQKMAEKD+KEEILKAF+LFDDDETGKISF+NLKRVAKELGENLTDEELQEMIDEADRD DGE+N++EFLRIMKKT LY
Sbjct:    4 TTAKRPALQGPVPPPRKKTTPKAELTEEQKQEIREAFELFDTDGSGFIDVKDLKVAMRALGFEPKKEEIKKMIGEVDKDATGKISFADFLTVMTQKMAEKDSKEEILKAFRLFDDDETGKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNQEEFLRIMKKTCLY 175

[Close]

BLAST of Centrin-1 vs. Ensembl Medaka
Match: cetn3 (centrin 3 [Source:NCBI gene;Acc:101165824])

HSP 1 Score: 183.726 bits (465), Expect = 2.893e-59
Identity = 95/155 (61.29%), Postives = 117/155 (75.48%), Query Frame = 3

Query:   54 NQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +Q  K     R ELTEEQK EV+EAFDLFD D    ID  ELKVAMRALGFE KK +V K++ DYD +G   I F DF  ++T ++ E+D KEE+LKAFKLFDDDE+G+IS +NL+RVA+ELGE++ DEEL+ MIDE D D DGEIN++EFL IM
Sbjct:    8 DQADKNKPNKRRELTEEQKHEVKEAFDLFDTDKDRQIDYHELKVAMRALGFEVKKMDVLKILKDYDRDGNRKITFEDFSEVVTDRILERDPKEEVLKAFKLFDDDESGRISLRNLRRVARELGEDINDEELRSMIDEFDTDRDGEINQEEFLAIM 162

HSP 2 Score: 50.0618 bits (118), Expect = 1.244e-7
Identity = 28/70 (40.00%), Postives = 43/70 (61.43%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT 302
            L  + K+EV +AF LFD D SG I ++ L+   R LG +   EE+R +I ++D +  G I   +FL++MT
Sbjct:   94 LERDPKEEVLKAFKLFDDDESGRISLRNLRRVARELGEDINDEELRSMIDEFDTDRDGEINQEEFLAIMT 163

[Close]

BLAST of Centrin-1 vs. Ensembl Medaka
Match: calm2a (calmodulin 2 [Source:NCBI gene;Acc:100049420])

HSP 1 Score: 142.124 bits (357), Expect = 3.914e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 58.5362 bits (140), Expect = 7.054e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 58.151 bits (139), Expect = 1.167e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149

[Close]

BLAST of Centrin-1 vs. Ensembl Medaka
Match: ENSORLT00000008599.2 (calmodulin 3 [Source:NCBI gene;Acc:100049421])

HSP 1 Score: 142.124 bits (357), Expect = 3.914e-43
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ +I + D +G G I+F +FL+MM +KM + D++EEI +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD D DG++N +EF+++M
Sbjct:    4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146

HSP 2 Score: 58.5362 bits (140), Expect = 7.054e-11
Identity = 34/75 (45.33%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  309 MAEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKK 524
            MA++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D +G I+  EFL +M +
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

HSP 3 Score: 58.151 bits (139), Expect = 1.167e-10
Identity = 36/97 (37.11%), Postives = 54/97 (55.67%), Query Frame = 3

Query:   51 INQKKKGGSG--DRPELTE---------EQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQK 308
            IN+    G+G  D PE            + ++E+REAF +FD DG+G I   EL+  M  LG +   EEV ++I + DI+G G + + +F+ MMT K
Sbjct:   53 INEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149

[Close]

BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000015458.1 (SMESG000015458.1)

HSP 1 Score: 306.99 bits (785), Expect = 6.365e-108
Identity = 160/173 (92.49%), Postives = 162/173 (93.64%), Query Frame = 3

Query:   18 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDET K   K  K+  K +  NLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY
Sbjct:    1 MTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETEKFLLK-FKKSCKRIRRNLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 172

[Close]

BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000052182.1 (SMESG000052182.1)

HSP 1 Score: 228.024 bits (580), Expect = 1.509e-77
Identity = 116/116 (100.00%), Postives = 116/116 (100.00%), Query Frame = 3

Query:  189 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY
Sbjct:    1 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 116

[Close]

BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000015458.1 (SMESG000015458.1)

HSP 1 Score: 197.208 bits (500), Expect = 2.248e-65
Identity = 103/116 (88.79%), Postives = 105/116 (90.52%), Query Frame = 3

Query:  189 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 536
            MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDET K   K  K+  K +  NLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY
Sbjct:    1 MRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETEKFLLK-FKKSCKRIRRNLTDEELQEMIDEADRDNDGEINEQEFLRIMKKTNLY 115

[Close]

BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000040368.1 (SMESG000040368.1)

HSP 1 Score: 148.288 bits (373), Expect = 8.042e-46
Identity = 72/123 (58.54%), Postives = 102/123 (82.93%), Query Frame = 3

Query:   90 ELTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMI 458
            EL+E+QK+++++AF+LFD DGSGTIDI+E+KVA+RAL FEP K+++RKLI++YD + KG I+F++FL +++ KM E D+KE+I KAF LFD D   KIS  NLK +++ LGENLTDEELQ ++
Sbjct:   13 ELSEKQKEDIQKAFNLFDKDGSGTIDIQEVKVALRALDFEPLKDDIRKLISEYDKDNKGTIDFNNFLILISSKMTEPDSKEDITKAFNLFDKDGKEKISIHNLKSISEILGENLTDEELQVVL 135

[Close]

BLAST of Centrin-1 vs. Planmine SMEST
Match: SMESG000016538.1 (SMESG000016538.1)

HSP 1 Score: 147.517 bits (371), Expect = 3.867e-45
Identity = 73/143 (51.05%), Postives = 109/143 (76.22%), Query Frame = 3

Query:   93 LTEEQKQEVREAFDLFDADGSGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGI-IEFSDFLSMMTQKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDNDGEINEQEFLRIM 518
            LT +Q+ E+ EAF+LFD+D  G +   E KV++RALGFE KK +V K+++D++I+     I+F DF  ++++ + E+D   E+++AFKLFDDDE+GKIS++NLK+VA+ELGE LTD E++ MI+E D+D DG IN +EF+ IM
Sbjct:   16 LTVDQRNEINEAFELFDSDKDGLLSQYEFKVSLRALGFEVKKHDVTKILSDFNIKDDAPKIKFDDFNEIVSEMILERDPTTEMIRAFKLFDDDESGKISYRNLKKVARELGETLTDHEIRAMIEEFDKDGDGSINMEEFMAIM 158

The following BLAST results are available for this feature:

BLAST of Centrin-1 vs. Ensembl Human
BLAST of Centrin-1 vs. Ensembl Celegans
BLAST of Centrin-1 vs. Ensembl Fly
BLAST of Centrin-1 vs. Ensembl Zebrafish
BLAST of Centrin-1 vs. Ensembl Xenopus
BLAST of Centrin-1 vs. Ensembl Mouse
BLAST of Centrin-1 vs. UniProt/SwissProt
BLAST of Centrin-1 vs. TrEMBL
BLAST of Centrin-1 vs. Ensembl Cavefish
BLAST of Centrin-1 vs. Ensembl Sea Lamprey
BLAST of Centrin-1 vs. Ensembl Yeast
BLAST of Centrin-1 vs. Ensembl Nematostella
BLAST of Centrin-1 vs. Ensembl Medaka
BLAST of Centrin-1 vs. Planmine SMEST

BLAST of Centrin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CETN2	1.862e-90	76.74	centrin 2 [Source:HGNC Symbol;Acc:HGNC:1867]	[more]
CETN1	8.443e-90	77.33	centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866]	[more]
CETN3	5.451e-56	61.38	centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868]	[more]
CETN3	4.469e-51	61.76	centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868]	[more]
CETN3	7.518e-51	61.48	centrin 3 [Source:HGNC Symbol;Acc:HGNC:1868]	[more]

BLAST of Centrin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cmd-1	1.085e-42	51.05	Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630...	[more]
cal-1	2.581e-34	44.14	Calmodulin-like protein [Source:UniProtKB/Swiss-P...	[more]
cal-1	5.052e-34	44.14	Calmodulin-like protein [Source:UniProtKB/Swiss-P...	[more]
cal-4	5.498e-31	40.51	CALmodulin related genes [Source:UniProtKB/TrEMBL...	[more]
cal-4	5.969e-31	40.51	CALmodulin related genes [Source:UniProtKB/TrEMBL...	[more]

BLAST of Centrin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG17493	4.937e-75	68.94	gene:FBgn0040010 transcript:FBtr0332630	[more]
CG17493	4.937e-75	68.94	gene:FBgn0040010 transcript:FBtr0332632	[more]
CG17493	4.937e-75	68.94	gene:FBgn0040010 transcript:FBtr0332631	[more]
CG31802	3.622e-57	53.76	gene:FBgn0051802 transcript:FBtr0081058	[more]
Cam	1.552e-42	51.05	gene:FBgn0000253 transcript:FBtr0304964	[more]

BLAST of Centrin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cetn4	5.666e-96	81.50	centrin 4 [Source:ZFIN;Acc:ZDB-GENE-030826-21]	[more]
cetn2	9.288e-90	76.16	centrin, EF-hand protein, 2 [Source:ZFIN;Acc:ZDB-G...	[more]
cetn3	3.286e-57	64.14	centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152]	[more]
cetn3	3.972e-57	64.14	centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152]	[more]
calm3a	4.647e-43	51.05	calmodulin 3a (phosphorylase kinase, delta) [Sourc...	[more]

BLAST of Centrin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cetn1	5.594e-92	79.07	centrin 1 [Source:NCBI gene;Acc:549903]	[more]
dtl	2.916e-90	76.30	denticleless E3 ubiquitin protein ligase homolog [...	[more]
cetn1	1.302e-89	85.43	centrin 1 [Source:NCBI gene;Acc:549903]	[more]
dtl	3.076e-89	79.75	denticleless E3 ubiquitin protein ligase homolog [...	[more]
rab38	1.538e-56	62.76	RAB38, member RAS oncogene family [Source:Xenbase;...	[more]

BLAST of Centrin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cetn2	2.030e-91	77.91	centrin 2 [Source:MGI Symbol;Acc:MGI:1347085]	[more]
Cetn2	2.165e-90	86.09	centrin 2 [Source:MGI Symbol;Acc:MGI:1347085]	[more]
Cetn2	2.165e-90	86.09	centrin 2 [Source:MGI Symbol;Acc:MGI:1347085]	[more]
Cetn1	3.814e-89	75.00	centrin 1 [Source:MGI Symbol;Acc:MGI:1347086]	[more]
Cetn1	3.814e-89	75.00	centrin 1 [Source:MGI Symbol;Acc:MGI:1347086]	[more]

BLAST of Centrin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q32LE3\|CETN1_BOVIN	8.718e-94	80.23	Centrin-1 OS=Bos taurus OX=9913 GN=CETN1 PE=2 SV=1	[more]
sp\|Q2TBN3\|CETN2_BOVIN	3.940e-91	77.33	Centrin-2 OS=Bos taurus OX=9913 GN=CETN2 PE=2 SV=1	[more]
sp\|Q9R1K9\|CETN2_MOUSE	1.420e-90	77.91	Centrin-2 OS=Mus musculus OX=10090 GN=Cetn2 PE=1 S...	[more]
sp\|P41208\|CETN2_HUMAN	8.942e-90	76.74	Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV...	[more]
sp\|Q12798\|CETN1_HUMAN	4.055e-89	77.33	Centrin-1 OS=Homo sapiens OX=9606 GN=CETN1 PE=1 SV...	[more]

BLAST of Centrin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A444U7H9	3.519e-94	82.56	Centrin-1 OS=Acipenser ruthenus OX=7906 GN=EOD39_1...	[more]
F1R789	1.268e-92	81.50	Centrin 4 OS=Danio rerio OX=7955 GN=cetn4 PE=4 SV=...	[more]
B1P0R9	1.580e-92	81.50	Centrin2 (Fragment) OS=Danio rerio OX=7955 GN=cetn...	[more]
A0A4W4F0V6	3.366e-92	81.98	Uncharacterized protein OS=Electrophorus electricu...	[more]
W5P165	4.833e-92	80.81	Centrin 1 OS=Ovis aries OX=9940 GN=CETN1 PE=4 SV=1	[more]

BLAST of Centrin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cetn4	2.682e-94	81.98	caltractin [Source:NCBI gene;Acc:103037928]	[more]
cetn4	2.956e-94	81.98	caltractin [Source:NCBI gene;Acc:103037928]	[more]
cetn2	1.570e-89	76.16	centrin-1 [Source:NCBI gene;Acc:103028142]	[more]
cetn3	2.120e-58	64.83	centrin 3 [Source:NCBI gene;Acc:103024517]	[more]
calm3a	3.938e-43	51.05	calmodulin [Source:NCBI gene;Acc:103037741]	[more]

BLAST of Centrin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CETN1	2.170e-94	77.09	centrin 1 [Source:HGNC Symbol;Acc:HGNC:1866]	[more]
cetn3	3.172e-53	56.29	centrin 3 [Source:ZFIN;Acc:ZDB-GENE-050522-152]	[more]
ENSPMAT00000006008.1	2.663e-44	51.05	pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-...	[more]
CALM3	7.989e-44	51.05	calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449]	[more]
CALML3	1.004e-43	51.05	calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145...	[more]

BLAST of Centrin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
CDC31	1.539e-52	59.44	Calcium-binding component of the spindle pole body...	[more]
CMD1	1.646e-36	44.44	Calmodulin; Ca2+ binding protein that regulates Ca...	[more]
MLC1	7.298e-15	31.62	Essential light chain for Myo1p; light chain for M...	[more]
CNB1	3.168e-9	29.17	Calcineurin B; regulatory subunit of calcineurin, ...	[more]

BLAST of Centrin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40775	1.156e-89	81.60	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44944	3.889e-59	60.78	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46518	3.250e-43	51.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46606	7.143e-40	50.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30674	1.069e-39	45.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Centrin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cetn2	2.496e-84	71.51	caltractin [Source:NCBI gene;Acc:101170769]	[more]
cetn2	2.496e-84	71.51	caltractin [Source:NCBI gene;Acc:101170769]	[more]
cetn3	2.893e-59	61.29	centrin 3 [Source:NCBI gene;Acc:101165824]	[more]
calm2a	3.914e-43	51.05	calmodulin 2 [Source:NCBI gene;Acc:100049420]	[more]
ENSORLT00000008599.2	3.914e-43	51.05	calmodulin 3 [Source:NCBI gene;Acc:100049421]	[more]

BLAST of Centrin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000015458.1	6.365e-108	92.49	SMESG000015458.1	[more]
SMESG000052182.1	1.509e-77	100.00	SMESG000052182.1	[more]
SMESG000015458.1	2.248e-65	88.79	SMESG000015458.1	[more]
SMESG000040368.1	8.042e-46	58.54	SMESG000040368.1	[more]
SMESG000016538.1	3.867e-45	51.05	SMESG000016538.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30015945 ID=SMED30015945|Name=Centrin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=599bp
ATCTATATAAATCTTATATGACTAGTCTAAAAAAAGGATCAGCAGGTGGA
ATCAACCAAAAGAAAAAAGGTGGTTCAGGTGATCGCCCAGAATTAACTGA
AGAACAGAAACAAGAAGTTCGAGAGGCTTTTGATTTATTTGATGCTGATG
GCTCAGGAACAATAGATATAAAAGAACTAAAAGTTGCCATGAGGGCTTTA
GGATTTGAACCCAAAAAAGAAGAAGTTCGGAAATTAATAGCTGATTATGA
TATCGAAGGAAAAGGCATCATTGAATTTAGTGATTTTCTTAGTATGATGA
CGCAAAAAATGGCAGAAAAAGATACGAAAGAAGAAATATTAAAAGCATTT
AAATTGTTCGATGATGATGAAACGGGAAAAATTTCTTTTAAAAATTTAAA
AAGAGTTGCAAAAGAATTAGGCGAAAATTTAACAGACGAAGAACTTCAAG
AAATGATTGATGAAGCTGATAGAGATAATGATGGAGAAATTAACGAGCAA
GAATTCTTAAGAATAATGAAGAAAACAAATTTATATTAGTGTTTTGTGTA
ATTATAAAATGAGCTTTGTAATATAATTGAAATTTTCCATTAAAAAAAA

protein sequence of SMED30015945-orf-1

>SMED30015945-orf-1 ID=SMED30015945-orf-1|Name=SMED30015945-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=179bp
LYKSYMTSLKKGSAGGINQKKKGGSGDRPELTEEQKQEVREAFDLFDADG
SGTIDIKELKVAMRALGFEPKKEEVRKLIADYDIEGKGIIEFSDFLSMMT
QKMAEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQE
MIDEADRDNDGEINEQEFLRIMKKTNLY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR037629	Centrin_2
IPR002048	EF_hand_dom
IPR011992	EF-hand-dom_pair
IPR018247	EF_Hand_1_Ca_BS
IPR000629	RNA-helicase_DEAD-box_CS

Vocabulary: **molecular function**
Term	Definition
GO:0005509	calcium ion binding
GO:0008017	microtubule binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0032795	heterotrimeric G-protein binding
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0000922	spindle pole
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005814	centriole
GO:0005815	microtubule organizing center
GO:0005856	cytoskeleton
GO:0032391	photoreceptor connecting cilium

Vocabulary: **biological process**
Term	Definition
GO:0007049	cell cycle
GO:0007067	mitotic nuclear division
GO:0034605	cellular response to heat
GO:0051301	cell division

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002048	EF-hand domain	SMART	SM00054	efh_1	coord: 140..168 e-value: 2.0E-8 score: 44.0 coord: 68..96 e-value: 0.0086 score: 25.3 coord: 32..60 e-value: 1.5E-8 score: 44.4
IPR002048	EF-hand domain	PFAM	PF13499	EF-hand_7	coord: 31..93 e-value: 2.1E-12 score: 47.3
IPR002048	EF-hand domain	PFAM	PF00036	EF-hand_1	coord: 140..167 e-value: 6.3E-9 score: 34.8
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 136..171 score: 14.458
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 28..63 score: 17.331
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 64..99 score: 11.64
IPR002048	EF-hand domain	CDD	cd00051	EFh	coord: 105..166 e-value: 3.04348E-10 score: 51.3945
IPR002048	EF-hand domain	CDD	cd00051	EFh	coord: 32..94 e-value: 1.0723E-15 score: 65.6469
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 90..170 e-value: 3.2E-18 score: 67.7
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 23..89 e-value: 1.9E-23 score: 84.5
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..30
None	No IPR available	PANTHER	PTHR23050	CALCIUM BINDING PROTEIN	coord: 17..171
IPR037629	Centrin 2	PANTHER	PTHR23050:SF305	CENTRIN-2	coord: 17..171
IPR000629	ATP-dependent RNA helicase DEAD-box, conserved site	PROSITE	PS00039	DEAD_ATP_HELICASE	coord: 144..152
IPR018247	EF-Hand 1, calcium-binding site	PROSITE	PS00018	EF_HAND_1	coord: 149..161
IPR018247	EF-Hand 1, calcium-binding site	PROSITE	PS00018	EF_HAND_1	coord: 41..53
IPR011992	EF-hand domain pair	SUPERFAMILY	SSF47473	EF-hand	coord: 23..167