Protein lethal(2) giant larvae
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015890 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Protein lethal(2) giant larvae vs. Ensembl Human
Match: LLGL2 (LLGL scribble cell polarity complex component 2 [Source:HGNC Symbol;Acc:HGNC:6629]) HSP 1 Score: 241.121 bits (614), Expect = 4.192e-65 Identity = 232/921 (25.19%), Postives = 396/921 (43.00%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLN-EVSYEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPS-VSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDR 2946
+PS + Y L +L I ++ G IK++G PGV + + + + I +PG VTL DN L LW + +EL + D L A SA IT + + + +G SG++ V+L + + I D ++ +LP +++R + + V + P +LIGY G +I+++Q V + + L + W +D + L SCH DGS W P +S+ + PY C I++ILW +Q +F GG+PR+ Y + I++++ + + D TS++I FT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + + N ED+ PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E+ + ++ DL ++WKG + G ++ FQ + + PP+ +T+L + + + ++A GT HG + + + CT+ P + LA EG R K +S R R R + R HP+ + + K R L E+ +R IE R + + G +R++ + +K + P +L+AG GG + F + P+ K+ Q HRAP++ +L S L E + DL P+ + H L+V++EEQ +++ P + K K+++TA +G R++ S+ F R
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASEL-QEDESFTLRGPPGAAPSA---------------TQITVVLPHSSCELLYLGTESGNVFVVQLPAFRA--------------------LEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWW------QRDGRL---------------LVSCHSDGSYCQW--PVSSEAQQPEPLRSLVPYGPF-PCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIH---------DGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNAHFSTMEWPIDGGTSLTPAPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGFGLFDHQQRRQ-----VFVKCTLHPSDQLAL------EGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCP-----SLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHS--VPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRR 855
BLAST of Protein lethal(2) giant larvae vs. Ensembl Human
Match: LLGL2 (LLGL scribble cell polarity complex component 2 [Source:HGNC Symbol;Acc:HGNC:6629]) HSP 1 Score: 241.121 bits (614), Expect = 4.578e-65 Identity = 231/921 (25.08%), Postives = 396/921 (43.00%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLN-EVSYEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPS-VSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDR 2946
+PS + Y L +L I ++ G IK++G PGV + + + + I +PG VTL DN L LW + +EL + D L A SA IT + + + +G SG++ V+L + + I D ++ +LP +++R + + V + P +LIGY G +I+++Q V + + L + W +D ++ SCH DGS W P +S+ + PY C I++ILW +Q +F GG+PR+ Y + I++++ + + D TS++I FT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + + N ED+ PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E+ + ++ DL ++WKG + G ++ FQ + + PP+ +T+L + + + ++A GT HG + + + CT+ P + LA EG R K +S R R R + R HP+ + + K R L E+ +R IE R + + G +R++ + +K + P +L+AG GG + F + P+ K+ Q HRAP++ +L S L E + DL P+ + H L+V++EEQ +++ P + K K+++TA +G R++ S+ F R
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASEL-QEDESFTLRGPPGAAPSA---------------TQITVVLPHSSCELLYLGTESGNVFVVQLPAFRA--------------------LEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWW------QRDGRLLV---------------SCHSDGSYCQW--PVSSEAQQPEPLRSLVPYGPF-PCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIH---------DGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNAHFSTMEWPIDGGTSLTPAPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGFGLFDHQQRRQ-----VFVKCTLHPSDQLAL------EGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCP-----SLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHS--VPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRR 855
BLAST of Protein lethal(2) giant larvae vs. Ensembl Human
Match: LLGL2 (LLGL scribble cell polarity complex component 2 [Source:HGNC Symbol;Acc:HGNC:6629]) HSP 1 Score: 241.121 bits (614), Expect = 4.922e-65 Identity = 232/921 (25.19%), Postives = 396/921 (43.00%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLN-EVSYEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPS-VSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDR 2946
+PS + Y L +L I ++ G IK++G PGV + + + + I +PG VTL DN L LW + +EL + D L A SA IT + + + +G SG++ V+L + + I D ++ +LP +++R + + V + P +LIGY G +I+++Q V + + L + W +D + L SCH DGS W P +S+ + PY C I++ILW +Q +F GG+PR+ Y + I++++ + + D TS++I FT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + + N ED+ PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E+ + ++ DL ++WKG + G ++ FQ + + PP+ +T+L + + + ++A GT HG + + + CT+ P + LA EG R K +S R R R + R HP+ + + K R L E+ +R IE R + + G +R++ + +K + P +L+AG GG + F + P+ K+ Q HRAP++ +L S L E + DL P+ + H L+V++EEQ +++ P + K K+++TA +G R++ S+ F R
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASEL-QEDESFTLRGPPGAAPSA---------------TQITVVLPHSSCELLYLGTESGNVFVVQLPAFRA--------------------LEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWW------QRDGRL---------------LVSCHSDGSYCQW--PVSSEAQQPEPLRSLVPYGPF-PCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIH---------DGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNAHFSTMEWPIDGGTSLTPAPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGFGLFDHQQRRQ-----VFVKCTLHPSDQLAL------EGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCP-----SLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHS--VPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRR 855
BLAST of Protein lethal(2) giant larvae vs. Ensembl Human
Match: LLGL1 (LLGL scribble cell polarity complex component 1 [Source:HGNC Symbol;Acc:HGNC:6628]) HSP 1 Score: 185.652 bits (470), Expect = 3.693e-47 Identity = 185/741 (24.97%), Postives = 327/741 (44.13%), Query Frame = 1
Query: 850 LLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQD-YLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFS-DWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVS--YEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXD-RPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENI----LKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+LIGY G +I+N VD + L +L W R+ S + S H DGS W++ ++ F L + + C I+KILW+ + + I+FSGG+PR+ Y + ++++ L + LD TS++IDF T+ +++ + L VL EEE ++DL WP + PYL LH+S IT ++ V + + ++ + +S + WPI G RN E Q LL+ GH DGT+ FW G ++ + + ++ LF+ D H + ++ EDD P R+ G FDP DD RL +Q L YT + +++ G GQ+++ + E+ + +DL F WKG + G + + FQ + + PP+ +TA+ + + + ++A GT HG + +++ + A CT+ P ++LA EG R K +S R + R + + + S L + N + + + + R D + G++R + + ++ +GP ++AG G + + + + + L K+ Q HRAP++ +L L E +A DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ + ++ + L C TN G
Sbjct: 211 ILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLCW---------------GRD------SSTVVSSHSDGSYAVWSV--DAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGHFIIFSGGMPRASYGDRHCVSVLRAETL---------VTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLEEELVVLDLQTPGWPAVP--APYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSSALSWPITGG----RNLAQEPSQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGLFQT-DCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQ-MVVAGTAGQVLVLELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAAVTAVTLHTE-----WSLVAFGTSHGFGLFDYQRKSPVLA-----RCTLHPNDSLAM------EGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDGAHHGP-----TMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRG--RPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFAS--VACEDYAETCLACLTNLG 885
BLAST of Protein lethal(2) giant larvae vs. Ensembl Human
Match: LLGL1 (LLGL scribble cell polarity complex component 1 [Source:HGNC Symbol;Acc:HGNC:6628]) HSP 1 Score: 185.652 bits (470), Expect = 3.693e-47 Identity = 185/741 (24.97%), Postives = 327/741 (44.13%), Query Frame = 1
Query: 850 LLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQD-YLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFS-DWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVS--YEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXD-RPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENI----LKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+LIGY G +I+N VD + L +L W R+ S + S H DGS W++ ++ F L + + C I+KILW+ + + I+FSGG+PR+ Y + ++++ L + LD TS++IDF T+ +++ + L VL EEE ++DL WP + PYL LH+S IT ++ V + + ++ + +S + WPI G RN E Q LL+ GH DGT+ FW G ++ + + ++ LF+ D H + ++ EDD P R+ G FDP DD RL +Q L YT + +++ G GQ+++ + E+ + +DL F WKG + G + + FQ + + PP+ +TA+ + + + ++A GT HG + +++ + A CT+ P ++LA EG R K +S R + R + + + S L + N + + + + R D + G++R + + ++ +GP ++AG G + + + + + L K+ Q HRAP++ +L L E +A DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ + ++ + L C TN G
Sbjct: 211 ILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLCW---------------GRD------SSTVVSSHSDGSYAVWSV--DAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGHFIIFSGGMPRASYGDRHCVSVLRAETL---------VTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLEEELVVLDLQTPGWPAVP--APYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSSALSWPITGG----RNLAQEPSQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGLFQT-DCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQ-MVVAGTAGQVLVLELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAAVTAVTLHTE-----WSLVAFGTSHGFGLFDYQRKSPVLA-----RCTLHPNDSLAM------EGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDGAHHGP-----TMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRG--RPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFAS--VACEDYAETCLACLTNLG 885
BLAST of Protein lethal(2) giant larvae vs. Ensembl Celegans
Match: tom-1 (TOMosyn synaptic protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWL6]) HSP 1 Score: 95.1301 bits (235), Expect = 1.977e-19 Identity = 90/390 (23.08%), Postives = 167/390 (42.82%), Query Frame = 1
Query: 793 RVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHL-NEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENK 1944
RV V ++ P LLI Y G + +N+ VD P DP P ++ ++ ++ + + DGSI +N ++++ Q +P+ C PI ++ WK + + +I+FSGG+P D + +TI+ K VL++ +I F ++ N S+ + VL + +F ++DL + P++ P+ +H SP+T + S+ D L + + + + S WP+ G R +L++ GH DG++ FW+ G ++ + +KSSS F+ +E+ ++VS+ I L C ++R LL+ G GQ+ L+ F + +
Sbjct: 181 RVHPGPVRQLAVSPAENTKLLIVYDKGIVVQWNLGTREVDRY-------------PLDP---------PIKSVNWHFDGRQILTGNVDGSISLYNHKKSTEAI-----QRTTPHGSG-PCRPIQQVEWKHMSETESIIMFSGGMPTDDGLPMPALTIL--------KGGKSATVLEMDWPIIQFIPLNQNIWNSIPQCPHSVAVLLKHDFMVLDLNQNGHPVIES--PHAMNIHESPVTCMAYYSDCPLDLIGALTLVGTKQRNKEFSARSWPVTGGLG--RECATGHQELVVTGHKDGSLKFWQ-ETGEHLQILYKLKSSSHFERLEEMETSDKVSHAVKYIEL---------CLESR-----------QLLVAGISGQVTLFRFTKQE 509
BLAST of Protein lethal(2) giant larvae vs. Ensembl Celegans
Match: tom-1 (TOMosyn synaptic protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWL6]) HSP 1 Score: 95.1301 bits (235), Expect = 2.058e-19 Identity = 90/390 (23.08%), Postives = 167/390 (42.82%), Query Frame = 1
Query: 793 RVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHL-NEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENK 1944
RV V ++ P LLI Y G + +N+ VD P DP P ++ ++ ++ + + DGSI +N ++++ Q +P+ C PI ++ WK + + +I+FSGG+P D + +TI+ K VL++ +I F ++ N S+ + VL + +F ++DL + P++ P+ +H SP+T + S+ D L + + + + S WP+ G R +L++ GH DG++ FW+ G ++ + +KSSS F+ +E+ ++VS+ I L C ++R LL+ G GQ+ L+ F + +
Sbjct: 181 RVHPGPVRQLAVSPAENTKLLIVYDKGIVVQWNLGTREVDRY-------------PLDP---------PIKSVNWHFDGRQILTGNVDGSISLYNHKKSTEAI-----QRTTPHGSG-PCRPIQQVEWKHMSETESIIMFSGGMPTDDGLPMPALTIL--------KGGKSATVLEMDWPIIQFIPLNQNIWNSIPQCPHSVAVLLKHDFMVLDLNQNGHPVIES--PHAMNIHESPVTCMAYYSDCPLDLIGALTLVGTKQRNKEFSARSWPVTGGLG--RECATGHQELVVTGHKDGSLKFWQ-ETGEHLQILYKLKSSSHFERLEEMETSDKVSHAVKYIEL---------CLESR-----------QLLVAGISGQVTLFRFTKQE 509
BLAST of Protein lethal(2) giant larvae vs. Ensembl Celegans
Match: tom-1 (TOMosyn synaptic protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWL6]) HSP 1 Score: 95.1301 bits (235), Expect = 2.089e-19 Identity = 90/390 (23.08%), Postives = 167/390 (42.82%), Query Frame = 1
Query: 793 RVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHL-NEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENK 1944
RV V ++ P LLI Y G + +N+ VD P DP P ++ ++ ++ + + DGSI +N ++++ Q +P+ C PI ++ WK + + +I+FSGG+P D + +TI+ K VL++ +I F ++ N S+ + VL + +F ++DL + P++ P+ +H SP+T + S+ D L + + + + S WP+ G R +L++ GH DG++ FW+ G ++ + +KSSS F+ +E+ ++VS+ I L C ++R LL+ G GQ+ L+ F + +
Sbjct: 181 RVHPGPVRQLAVSPAENTKLLIVYDKGIVVQWNLGTREVDRY-------------PLDP---------PIKSVNWHFDGRQILTGNVDGSISLYNHKKSTEAI-----QRTTPHGSG-PCRPIQQVEWKHMSETESIIMFSGGMPTDDGLPMPALTIL--------KGGKSATVLEMDWPIIQFIPLNQNIWNSIPQCPHSVAVLLKHDFMVLDLNQNGHPVIES--PHAMNIHESPVTCMAYYSDCPLDLIGALTLVGTKQRNKEFSARSWPVTGGLG--RECATGHQELVVTGHKDGSLKFWQ-ETGEHLQILYKLKSSSHFERLEEMETSDKVSHAVKYIEL---------CLESR-----------QLLVAGISGQVTLFRFTKQE 509
BLAST of Protein lethal(2) giant larvae vs. Ensembl Celegans
Match: tom-1 (TOMosyn synaptic protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWL6]) HSP 1 Score: 94.7449 bits (234), Expect = 2.569e-19 Identity = 90/390 (23.08%), Postives = 167/390 (42.82%), Query Frame = 1
Query: 793 RVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHL-NEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENK 1944
RV V ++ P LLI Y G + +N+ VD P DP P ++ ++ ++ + + DGSI +N ++++ Q +P+ C PI ++ WK + + +I+FSGG+P D + +TI+ K VL++ +I F ++ N S+ + VL + +F ++DL + P++ P+ +H SP+T + S+ D L + + + + S WP+ G R +L++ GH DG++ FW+ G ++ + +KSSS F+ +E+ ++VS+ I L C ++R LL+ G GQ+ L+ F + +
Sbjct: 181 RVHPGPVRQLAVSPAENTKLLIVYDKGIVVQWNLGTREVDRY-------------PLDP---------PIKSVNWHFDGRQILTGNVDGSISLYNHKKSTEAI-----QRTTPHGSG-PCRPIQQVEWKHMSETESIIMFSGGMPTDDGLPMPALTIL--------KGGKSATVLEMDWPIIQFIPLNQNIWNSIPQCPHSVAVLLKHDFMVLDLNQNGHPVIES--PHAMNIHESPVTCMAYYSDCPLDLIGALTLVGTKQRNKEFSARSWPVTGGLG--RECATGHQELVVTGHKDGSLKFWQ-ETGEHLQILYKLKSSSHFERLEEMETSDKVSHAVKYIEL---------CLESR-----------QLLVAGISGQVTLFRFTKQE 509
BLAST of Protein lethal(2) giant larvae vs. Ensembl Celegans
Match: tom-1 (TOMosyn synaptic protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWL6]) HSP 1 Score: 94.7449 bits (234), Expect = 2.662e-19 Identity = 90/390 (23.08%), Postives = 167/390 (42.82%), Query Frame = 1
Query: 793 RVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHL-NEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENK 1944
RV V ++ P LLI Y G + +N+ VD P DP P ++ ++ ++ + + DGSI +N ++++ Q +P+ C PI ++ WK + + +I+FSGG+P D + +TI+ K VL++ +I F ++ N S+ + VL + +F ++DL + P++ P+ +H SP+T + S+ D L + + + + S WP+ G R +L++ GH DG++ FW+ G ++ + +KSSS F+ +E+ ++VS+ I L C ++R LL+ G GQ+ L+ F + +
Sbjct: 181 RVHPGPVRQLAVSPAENTKLLIVYDKGIVVQWNLGTREVDRY-------------PLDP---------PIKSVNWHFDGRQILTGNVDGSISLYNHKKSTEAI-----QRTTPHGSG-PCRPIQQVEWKHMSETESIIMFSGGMPTDDGLPMPALTIL--------KGGKSATVLEMDWPIIQFIPLNQNIWNSIPQCPHSVAVLLKHDFMVLDLNQNGHPVIES--PHAMNIHESPVTCMAYYSDCPLDLIGALTLVGTKQRNKEFSARSWPVTGGLG--RECATGHQELVVTGHKDGSLKFWQ-ETGEHLQILYKLKSSSHFERLEEMETSDKVSHAVKYIEL---------CLESR-----------QLLVAGISGQVTLFRFTKQE 509
BLAST of Protein lethal(2) giant larvae vs. Ensembl Fly
Match: l(2)gl (gene:FBgn0002121 transcript:FBtr0330655) HSP 1 Score: 142.124 bits (357), Expect = 8.378e-34 Identity = 146/566 (25.80%), Postives = 246/566 (43.46%), Query Frame = 1
Query: 706 GNTIWQM-----PTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL-----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKG------YAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELH------LNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGK--HLLIGGYGGQIVLWGFQE--NKYEKHLLDVDLTTHLSNFKWKGCQPFQ------HIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTH-CTVPRNTLASQEASLGEGWARRRT 2304
G I+Q+ K VI D ++ ++P ++ A+ I P S LL+ Y G ++++ + SV ++ P V +E +Y H DGS TW++ P N + + PY D C I+++ + + + +IVFSGG+PRS Y +++C+ ++ + LD TS++IDF +N+ E L+VL EEE DLT + I + PYL+ +H S +T SEV ++ + + +++D + S WPI G + V D ++L+ GH DG++ FW G +K I K+SS+F + ++ ++ E P R++G FDP DD RLA++ I + K L++GG GQIV+ F + K + ++L + F WKG E T + + + PP+ IT + + + +++ GT HGLV+ + + V H CT+ N L GE +RR++
Sbjct: 149 GGNIYQLDLHTFTIKEPVIYHDVVLEQVP--PAYKLNPGAIESIRQLPNSPSKLLVAYNRGLCVLWDFESASVQ-----------RAYIAPGHGQSVGLTVNFEGSEFTWY--------HADGSYATWSIDNPEPPSNVN---------YVPYGPD-PCKSINRLYKGKRRSNDVIVFSGGMPRSAYG--------DHNCVSVHASDGHKVCLDFTSKVIDFFVTFENNRDVAEVLVVLLEEELCAYDLTDPN--ICAIKAPYLHSVHASAVTCNYLASEVVQSVYESILR-AGDEQDIDYSNISWPITGGTLPDNLEESVEEDATKLYEILLTGHEDGSVKFWDC-TGVLLKPIYNFKTSSIFGSESDFRDDAAADMSAEQVDEGEPPFRKSGLFDPYSDDPRLAVKKIAFCPKTGQLIVGGTAGQIVIADFIDLPEKVSLKYISMNLVSDRDGFVWKGHDQLNVRSNLLDGEAIPTTERGVNISGVLQVLPPASITCMALEAS-----WGLVSGGTAHGLVLF------DFKNFVPVFHRCTLNPNDLTGA----GEQLSRRKS 656
BLAST of Protein lethal(2) giant larvae vs. Ensembl Fly
Match: l(2)gl (gene:FBgn0002121 transcript:FBtr0306592) HSP 1 Score: 142.124 bits (357), Expect = 8.947e-34 Identity = 146/566 (25.80%), Postives = 246/566 (43.46%), Query Frame = 1
Query: 706 GNTIWQM-----PTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL-----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKG------YAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELH------LNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGK--HLLIGGYGGQIVLWGFQE--NKYEKHLLDVDLTTHLSNFKWKGCQPFQ------HIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTH-CTVPRNTLASQEASLGEGWARRRT 2304
G I+Q+ K VI D ++ ++P ++ A+ I P S LL+ Y G ++++ + SV ++ P V +E +Y H DGS TW++ P N + + PY D C I+++ + + + +IVFSGG+PRS Y +++C+ ++ + LD TS++IDF +N+ E L+VL EEE DLT + I + PYL+ +H S +T SEV ++ + + +++D + S WPI G + V D ++L+ GH DG++ FW G +K I K+SS+F + ++ ++ E P R++G FDP DD RLA++ I + K L++GG GQIV+ F + K + ++L + F WKG E T + + + PP+ IT + + + +++ GT HGLV+ + + V H CT+ N L GE +RR++
Sbjct: 149 GGNIYQLDLHTFTIKEPVIYHDVVLEQVP--PAYKLNPGAIESIRQLPNSPSKLLVAYNRGLCVLWDFESASVQ-----------RAYIAPGHGQSVGLTVNFEGSEFTWY--------HADGSYATWSIDNPEPPSNVN---------YVPYGPD-PCKSINRLYKGKRRSNDVIVFSGGMPRSAYG--------DHNCVSVHASDGHKVCLDFTSKVIDFFVTFENNRDVAEVLVVLLEEELCAYDLTDPN--ICAIKAPYLHSVHASAVTCNYLASEVVQSVYESILR-AGDEQDIDYSNISWPITGGTLPDNLEESVEEDATKLYEILLTGHEDGSVKFWDC-TGVLLKPIYNFKTSSIFGSESDFRDDAAADMSAEQVDEGEPPFRKSGLFDPYSDDPRLAVKKIAFCPKTGQLIVGGTAGQIVIADFIDLPEKVSLKYISMNLVSDRDGFVWKGHDQLNVRSNLLDGEAIPTTERGVNISGVLQVLPPASITCMALEAS-----WGLVSGGTAHGLVLF------DFKNFVPVFHRCTLNPNDLTGA----GEQLSRRKS 656
BLAST of Protein lethal(2) giant larvae vs. Ensembl Fly
Match: l(2)gl (gene:FBgn0002121 transcript:FBtr0306590) HSP 1 Score: 142.124 bits (357), Expect = 8.947e-34 Identity = 146/566 (25.80%), Postives = 246/566 (43.46%), Query Frame = 1
Query: 706 GNTIWQM-----PTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL-----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKG------YAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELH------LNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGK--HLLIGGYGGQIVLWGFQE--NKYEKHLLDVDLTTHLSNFKWKGCQPFQ------HIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTH-CTVPRNTLASQEASLGEGWARRRT 2304
G I+Q+ K VI D ++ ++P ++ A+ I P S LL+ Y G ++++ + SV ++ P V +E +Y H DGS TW++ P N + + PY D C I+++ + + + +IVFSGG+PRS Y +++C+ ++ + LD TS++IDF +N+ E L+VL EEE DLT + I + PYL+ +H S +T SEV ++ + + +++D + S WPI G + V D ++L+ GH DG++ FW G +K I K+SS+F + ++ ++ E P R++G FDP DD RLA++ I + K L++GG GQIV+ F + K + ++L + F WKG E T + + + PP+ IT + + + +++ GT HGLV+ + + V H CT+ N L GE +RR++
Sbjct: 149 GGNIYQLDLHTFTIKEPVIYHDVVLEQVP--PAYKLNPGAIESIRQLPNSPSKLLVAYNRGLCVLWDFESASVQ-----------RAYIAPGHGQSVGLTVNFEGSEFTWY--------HADGSYATWSIDNPEPPSNVN---------YVPYGPD-PCKSINRLYKGKRRSNDVIVFSGGMPRSAYG--------DHNCVSVHASDGHKVCLDFTSKVIDFFVTFENNRDVAEVLVVLLEEELCAYDLTDPN--ICAIKAPYLHSVHASAVTCNYLASEVVQSVYESILR-AGDEQDIDYSNISWPITGGTLPDNLEESVEEDATKLYEILLTGHEDGSVKFWDC-TGVLLKPIYNFKTSSIFGSESDFRDDAAADMSAEQVDEGEPPFRKSGLFDPYSDDPRLAVKKIAFCPKTGQLIVGGTAGQIVIADFIDLPEKVSLKYISMNLVSDRDGFVWKGHDQLNVRSNLLDGEAIPTTERGVNISGVLQVLPPASITCMALEAS-----WGLVSGGTAHGLVLF------DFKNFVPVFHRCTLNPNDLTGA----GEQLSRRKS 656
BLAST of Protein lethal(2) giant larvae vs. Ensembl Fly
Match: l(2)gl (gene:FBgn0002121 transcript:FBtr0306589) HSP 1 Score: 142.124 bits (357), Expect = 8.947e-34 Identity = 146/566 (25.80%), Postives = 246/566 (43.46%), Query Frame = 1
Query: 706 GNTIWQM-----PTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL-----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKG------YAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELH------LNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGK--HLLIGGYGGQIVLWGFQE--NKYEKHLLDVDLTTHLSNFKWKGCQPFQ------HIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTH-CTVPRNTLASQEASLGEGWARRRT 2304
G I+Q+ K VI D ++ ++P ++ A+ I P S LL+ Y G ++++ + SV ++ P V +E +Y H DGS TW++ P N + + PY D C I+++ + + + +IVFSGG+PRS Y +++C+ ++ + LD TS++IDF +N+ E L+VL EEE DLT + I + PYL+ +H S +T SEV ++ + + +++D + S WPI G + V D ++L+ GH DG++ FW G +K I K+SS+F + ++ ++ E P R++G FDP DD RLA++ I + K L++GG GQIV+ F + K + ++L + F WKG E T + + + PP+ IT + + + +++ GT HGLV+ + + V H CT+ N L GE +RR++
Sbjct: 149 GGNIYQLDLHTFTIKEPVIYHDVVLEQVP--PAYKLNPGAIESIRQLPNSPSKLLVAYNRGLCVLWDFESASVQ-----------RAYIAPGHGQSVGLTVNFEGSEFTWY--------HADGSYATWSIDNPEPPSNVN---------YVPYGPD-PCKSINRLYKGKRRSNDVIVFSGGMPRSAYG--------DHNCVSVHASDGHKVCLDFTSKVIDFFVTFENNRDVAEVLVVLLEEELCAYDLTDPN--ICAIKAPYLHSVHASAVTCNYLASEVVQSVYESILR-AGDEQDIDYSNISWPITGGTLPDNLEESVEEDATKLYEILLTGHEDGSVKFWDC-TGVLLKPIYNFKTSSIFGSESDFRDDAAADMSAEQVDEGEPPFRKSGLFDPYSDDPRLAVKKIAFCPKTGQLIVGGTAGQIVIADFIDLPEKVSLKYISMNLVSDRDGFVWKGHDQLNVRSNLLDGEAIPTTERGVNISGVLQVLPPASITCMALEAS-----WGLVSGGTAHGLVLF------DFKNFVPVFHRCTLNPNDLTGA----GEQLSRRKS 656
BLAST of Protein lethal(2) giant larvae vs. Ensembl Fly
Match: l(2)gl (gene:FBgn0002121 transcript:FBtr0306591) HSP 1 Score: 142.124 bits (357), Expect = 8.947e-34 Identity = 146/566 (25.80%), Postives = 246/566 (43.46%), Query Frame = 1
Query: 706 GNTIWQM-----PTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL-----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKG------YAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELH------LNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGK--HLLIGGYGGQIVLWGFQE--NKYEKHLLDVDLTTHLSNFKWKGCQPFQ------HIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTH-CTVPRNTLASQEASLGEGWARRRT 2304
G I+Q+ K VI D ++ ++P ++ A+ I P S LL+ Y G ++++ + SV ++ P V +E +Y H DGS TW++ P N + + PY D C I+++ + + + +IVFSGG+PRS Y +++C+ ++ + LD TS++IDF +N+ E L+VL EEE DLT + I + PYL+ +H S +T SEV ++ + + +++D + S WPI G + V D ++L+ GH DG++ FW G +K I K+SS+F + ++ ++ E P R++G FDP DD RLA++ I + K L++GG GQIV+ F + K + ++L + F WKG E T + + + PP+ IT + + + +++ GT HGLV+ + + V H CT+ N L GE +RR++
Sbjct: 149 GGNIYQLDLHTFTIKEPVIYHDVVLEQVP--PAYKLNPGAIESIRQLPNSPSKLLVAYNRGLCVLWDFESASVQ-----------RAYIAPGHGQSVGLTVNFEGSEFTWY--------HADGSYATWSIDNPEPPSNVN---------YVPYGPD-PCKSINRLYKGKRRSNDVIVFSGGMPRSAYG--------DHNCVSVHASDGHKVCLDFTSKVIDFFVTFENNRDVAEVLVVLLEEELCAYDLTDPN--ICAIKAPYLHSVHASAVTCNYLASEVVQSVYESILR-AGDEQDIDYSNISWPITGGTLPDNLEESVEEDATKLYEILLTGHEDGSVKFWDC-TGVLLKPIYNFKTSSIFGSESDFRDDAAADMSAEQVDEGEPPFRKSGLFDPYSDDPRLAVKKIAFCPKTGQLIVGGTAGQIVIADFIDLPEKVSLKYISMNLVSDRDGFVWKGHDQLNVRSNLLDGEAIPTTERGVNISGVLQVLPPASITCMALEAS-----WGLVSGGTAHGLVLF------DFKNFVPVFHRCTLNPNDLTGA----GEQLSRRKS 656
BLAST of Protein lethal(2) giant larvae vs. Ensembl Zebrafish
Match: llgl1 (LLGL scribble cell polarity complex component 1 [Source:ZFIN;Acc:ZDB-GENE-060825-69]) HSP 1 Score: 236.884 bits (603), Expect = 7.451e-64 Identity = 244/955 (25.55%), Postives = 421/955 (44.08%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKS---DVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTID----DNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNI-SFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDV---DLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLA---------SQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + YD KL L+ I +K G IKI+G PGV + + + I F+ G ++L DN + LW I N ++V S N+ IE T +M L+ + +LL + + G ++PT + + +D I+ +P + + V + P +LIGY G +++++ VD L K L +L W R+ + SS H DG + W + P D V + P+ C ++KILW+ + L++FSGG+PR+ Y + +TI+ +S H+ LD TS++IDF TI + D L+VL EEE ++DL WP + PYL LH+S IT +S V ++++ +S+ ++ C + ++ +WPI G + + Q +LL+ GH DGT+ FW G +K + + ++S+F+ D H + ++ +E P R+ G FDP DD RL IQ L Y+GK L++ G GQ+++ + K + H++DV DL F WKG GS+ FQ ++ + PP+ +TA+ + + N +IA GT HG + + + + A CT+ P ++LA S + SL + + R R + R + + HL+D++ + +R IE R D + G++R + + ++ +GP ++AG G + + D + + L K+ Q HRAP++ +L + L E + DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ +++++ ++ L+C TN G
Sbjct: 9 QPSALAYDPKLQLMAIGTKSGAIKIYGAPGVEMTGLHKDTAAVTQIHFLCGQGRILSLLDDNTIHLWEIVQRENRSHLLEVHS-FNLPGRP-----------------------GIESTSATRVTVM------LLNLSCNLLALGTEGG-------GVHFLELPTLTLLNKSLFQDEIMQSVPEEYKCGKSLGPVESLQEHPKDSDKILIGYSRGLVVLWDLSSRHVDNLFLGKQQLESLVW---------------ERSGNSFVSS------HSDGGYMVWAVSSSNPCTHDP--VSSTIPYGPFP----CKAVNKILWRTTESGAPLVLFSGGMPRASYGDRHCLTILQDS---------SHVTLDFTSRVIDFFTIHCTDTEKDFDEPSALVVLLEEELVVIDLQMPGWPTV--PAPYLAPLHSSAITCSCHISNVPPKLWERV--ISAGQQQCPLQNYENWPICGGKNLAPDPK--QKELLLTGHEDGTVRFWD-ASGVSLKPLYKLSTASIFQ-TDCEHNDSLTQAGEEEWPPFRKVGCFDPYSDDPRLGIQKISLCKYSGK-LVVAGTAGQVIVMVLGDEKSD-HMIDVATVDLLQDREGFTWKGHDRLPPKSGSVVFAPGFQPVVLVQCLPPAAVTAVTLHAEWN-----LIAFGTSHGFGLFDYHRRSPVLA-----RCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRVVVNSPTSKVQ------EANAHLADHDAEV----------TPVQRRIEPRSADDSLSGVVRCLCFADTFLRDGTHHGP-----TMWAGTNSGSVYAYALDVPSQEKFSEQSVEALLGKEIQLMHRAPVVSIAVLDGRG--NPLPEPYEVSRDLAKAPDMQGSHSVLIASEEQFKVFMLPKVSAKTKFKLTAHEGCRVRKVALANFTS--VSSEDYSENALVCLTNMG 845
BLAST of Protein lethal(2) giant larvae vs. Ensembl Zebrafish
Match: llgl1 (LLGL scribble cell polarity complex component 1 [Source:ZFIN;Acc:ZDB-GENE-060825-69]) HSP 1 Score: 237.269 bits (604), Expect = 7.913e-64 Identity = 244/955 (25.55%), Postives = 421/955 (44.08%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKS---DVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTID----DNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNI-SFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDV---DLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLA---------SQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + YD KL L+ I +K G IKI+G PGV + + + I F+ G ++L DN + LW I N ++V S N+ IE T +M L+ + +LL + + G ++PT + + +D I+ +P + + V + P +LIGY G +++++ VD L K L +L W R+ + SS H DG + W + P D V + P+ C ++KILW+ + L++FSGG+PR+ Y + +TI+ +S H+ LD TS++IDF TI + D L+VL EEE ++DL WP + PYL LH+S IT +S V ++++ +S+ ++ C + ++ +WPI G + + Q +LL+ GH DGT+ FW G +K + + ++S+F+ D H + ++ +E P R+ G FDP DD RL IQ L Y+GK L++ G GQ+++ + K + H++DV DL F WKG GS+ FQ ++ + PP+ +TA+ + + N +IA GT HG + + + + A CT+ P ++LA S + SL + + R R + R + + HL+D++ + +R IE R D + G++R + + ++ +GP ++AG G + + D + + L K+ Q HRAP++ +L + L E + DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ +++++ ++ L+C TN G
Sbjct: 36 QPSALAYDPKLQLMAIGTKSGAIKIYGAPGVEMTGLHKDTAAVTQIHFLCGQGRILSLLDDNTIHLWEIVQRENRSHLLEVHS-FNLPGRP-----------------------GIESTSATRVTVM------LLNLSCNLLALGTEGG-------GVHFLELPTLTLLNKSLFQDEIMQSVPEEYKCGKSLGPVESLQEHPKDSDKILIGYSRGLVVLWDLSSRHVDNLFLGKQQLESLVW---------------ERSGNSFVSS------HSDGGYMVWAVSSSNPCTHDP--VSSTIPYGPFP----CKAVNKILWRTTESGAPLVLFSGGMPRASYGDRHCLTILQDS---------SHVTLDFTSRVIDFFTIHCTDTEKDFDEPSALVVLLEEELVVIDLQMPGWPTV--PAPYLAPLHSSAITCSCHISNVPPKLWERV--ISAGQQQCPLQNYENWPICGGKNLAPDPK--QKELLLTGHEDGTVRFWD-ASGVSLKPLYKLSTASIFQ-TDCEHNDSLTQAGEEEWPPFRKVGCFDPYSDDPRLGIQKISLCKYSGK-LVVAGTAGQVIVMVLGDEKSD-HMIDVATVDLLQDREGFTWKGHDRLPPKSGSVVFAPGFQPVVLVQCLPPAAVTAVTLHAEWN-----LIAFGTSHGFGLFDYHRRSPVLA-----RCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRVVVNSPTSKVQ------EANAHLADHDAEV----------TPVQRRIEPRSADDSLSGVVRCLCFADTFLRDGTHHGP-----TMWAGTNSGSVYAYALDVPSQEKFSEQSVEALLGKEIQLMHRAPVVSIAVLDGRG--NPLPEPYEVSRDLAKAPDMQGSHSVLIASEEQFKVFMLPKVSAKTKFKLTAHEGCRVRKVALANFTS--VSSEDYSENALVCLTNMG 872
BLAST of Protein lethal(2) giant larvae vs. Ensembl Zebrafish
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:795670]) HSP 1 Score: 211.46 bits (537), Expect = 1.328e-55 Identity = 237/957 (24.76%), Postives = 406/957 (42.42%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTN--ELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI--DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+ Y+ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W + + EL ++ + L+ A S +TA+ + +++G G + V++ + ++ N I + + +++P R +++V + P + + +LIGY G +++++ + L ++ W ++D + S H DGS W + PQ E + F C ISKI+ KQ ++FSGG+PR+ Y + I+++++ H LD TS++IDF I +N G L+VL EEE +VDL E WP++ + PYL LH S IT +S + ++++ ++ ++ + S WPI G + + D Q DLL+ GH DGT+ FW G C+ + + ++ +F AD E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + E+ + VDL F+WKG E + FQ + PP+ +TA+ + + + ++ GT HG + + N + CT+ P + +A EG R K +S R R R + R H + + L + N + L E E+ +R IE R D + GL+R++ + + + P +L+AG GG + + + P+ K+ Q HRAP++ +L + + L E + DL R P+ HL+V++EEQ +L+ P + K K+++TA DG R++ + F T + L+ TN G
Sbjct: 19 DLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFT-LSGPPGAIPSV---------------TRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENN--------------------ISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWW------MEDGESIL---------------SSHSDGSYCQWTVTGEDPQTEPEKQETPYGAFP-------CKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSKT---------HEALDFTSRIIDFFVIREGENHKGEPSALVVLVEEELVVVDLQTEGWPVI--QTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAH-QNTHYSRKPWPING-GKNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLYPMYKLSTAGVFHTDADPNDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVLFPPGFQPFALVQCQPPAVVTAIALHSE-----WKLVGFGTSHGFGLYDYNQRNN-----IMVKCTLNPSDQMAM------EGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNNAAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTP-----SLWAGTNGGAVFAYVLRVPPQERRAEDPVTAHAAKEIQLMHRAPVVGLVVLDGKG--APLPEPLEVAHDL--ARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGS---RTDEQLESCLVVLTNQG 867
BLAST of Protein lethal(2) giant larvae vs. Ensembl Zebrafish
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:795670]) HSP 1 Score: 211.46 bits (537), Expect = 1.328e-55 Identity = 237/957 (24.76%), Postives = 406/957 (42.42%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTN--ELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI--DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+ Y+ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W + + EL ++ + L+ A S +TA+ + +++G G + V++ + ++ N I + + +++P R +++V + P + + +LIGY G +++++ + L ++ W ++D + S H DGS W + PQ E + F C ISKI+ KQ ++FSGG+PR+ Y + I+++++ H LD TS++IDF I +N G L+VL EEE +VDL E WP++ + PYL LH S IT +S + ++++ ++ ++ + S WPI G + + D Q DLL+ GH DGT+ FW G C+ + + ++ +F AD E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + E+ + VDL F+WKG E + FQ + PP+ +TA+ + + + ++ GT HG + + N + CT+ P + +A EG R K +S R R R + R H + + L + N + L E E+ +R IE R D + GL+R++ + + + P +L+AG GG + + + P+ K+ Q HRAP++ +L + + L E + DL R P+ HL+V++EEQ +L+ P + K K+++TA DG R++ + F T + L+ TN G
Sbjct: 19 DLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFT-LSGPPGAIPSV---------------TRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENN--------------------ISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWW------MEDGESIL---------------SSHSDGSYCQWTVTGEDPQTEPEKQETPYGAFP-------CKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSKT---------HEALDFTSRIIDFFVIREGENHKGEPSALVVLVEEELVVVDLQTEGWPVI--QTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAH-QNTHYSRKPWPING-GKNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLYPMYKLSTAGVFHTDADPNDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVLFPPGFQPFALVQCQPPAVVTAIALHSE-----WKLVGFGTSHGFGLYDYNQRNN-----IMVKCTLNPSDQMAM------EGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNNAAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTP-----SLWAGTNGGAVFAYVLRVPPQERRAEDPVTAHAAKEIQLMHRAPVVGLVVLDGKG--APLPEPLEVAHDL--ARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGS---RTDEQLESCLVVLTNQG 867
BLAST of Protein lethal(2) giant larvae vs. Ensembl Zebrafish
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:795670]) HSP 1 Score: 211.46 bits (537), Expect = 1.416e-55 Identity = 237/957 (24.76%), Postives = 406/957 (42.42%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTN--ELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI--DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+ Y+ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W + + EL ++ + L+ A S +TA+ + +++G G + V++ + ++ N I + + +++P R +++V + P + + +LIGY G +++++ + L ++ W ++D + S H DGS W + PQ E + F C ISKI+ KQ ++FSGG+PR+ Y + I+++++ H LD TS++IDF I +N G L+VL EEE +VDL E WP++ + PYL LH S IT +S + ++++ ++ ++ + S WPI G + + D Q DLL+ GH DGT+ FW G C+ + + ++ +F AD E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + E+ + VDL F+WKG E + FQ + PP+ +TA+ + + + ++ GT HG + + N + CT+ P + +A EG R K +S R R R + R H + + L + N + L E E+ +R IE R D + GL+R++ + + + P +L+AG GG + + + P+ K+ Q HRAP++ +L + + L E + DL R P+ HL+V++EEQ +L+ P + K K+++TA DG R++ + F T + L+ TN G
Sbjct: 19 DLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFT-LSGPPGAIPSV---------------TRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENN--------------------ISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWW------MEDGESIL---------------SSHSDGSYCQWTVTGEDPQTEPEKQETPYGAFP-------CKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSKT---------HEALDFTSRIIDFFVIREGENHKGEPSALVVLVEEELVVVDLQTEGWPVI--QTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAH-QNTHYSRKPWPING-GKNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLYPMYKLSTAGVFHTDADPNDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVLFPPGFQPFALVQCQPPAVVTAIALHSE-----WKLVGFGTSHGFGLYDYNQRNN-----IMVKCTLNPSDQMAM------EGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNNAAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTP-----SLWAGTNGGAVFAYVLRVPPQERRAEDPVTAHAAKEIQLMHRAPVVGLVVLDGKG--APLPEPLEVAHDL--ARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGS---RTDEQLESCLVVLTNQG 867
BLAST of Protein lethal(2) giant larvae vs. Ensembl Xenopus
Match: LLGL1 (LLGL1, scribble cell polarity complex component [Source:NCBI gene;Acc:100486472]) HSP 1 Score: 221.09 bits (562), Expect = 1.942e-58 Identity = 235/946 (24.84%), Postives = 400/946 (42.28%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVID----RDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEF--LVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFS--DWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + +D L ++ I +K G +KI+G PGV ++ + + + F+PG ++L DN + LW EL + D S+L S N S +V + L+ + T G Q+P+ + + +D I+ LP + + V + P R +LIGY G ++++ + V+ L L ++ W R + SS H DG + W +S V + P+ C I+KI W+ + I+FSGG+PR+ Y + +TI+ L + LD TS+++DF T+ ++DS + L+VL EEE ++DL WP + PYL LH+S IT +S V + ++++ S E N FS +WPI G RN +E Q LL+ GH DGT+ FW G ++ + + ++ +F+ D H + +DE P R+ G FDP DD RL IQ L Y+GK +L+ G GQ+++ + K E ++ VDL F WKG GS+ FQ + + PP+ +TA+ + + N ++A GT HG + + + + A CT+ N + E L + +++ R ++ P SR N + + ++ +R IE R D + G++R + + ++ +GP ++AG G + + + L + L K+ Q HRAP++ +L + L E + DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ T+ + ++ L C TN G
Sbjct: 36 QPSSLAFDPLLRIMAIGAKSGAVKIYGAPGVEFTGLHKDTATVTQMHFLPGQGRLLSLLDDNTMHLW-------ELQQKDGSSHLEETRSFLLPGK--------------------------PGFDCANSPPSFTRVTVILITASCEVAGLGTEGGGVYFIQIPSLKLLEEKTLLQDEIVKSLPEEYRCGKTLGPVESLQEHPCQRGKILIGYSRGLVVLWDQEGRKVEHLFLGNQQLESVFW---------------GRKGTSFISS------HSDGGYMVWEADSDSSTTSQPVTSKIPYGPFP----CKAINKIQWRSSSSGNPYIIFSGGMPRASYGDRHCVTILQGQNL---------VTLDFTSRVVDFFTVCPLKSEDDSDNPTALVVLVEEELVVIDLQTPGWPTVP--TPYLAPLHSSAITCAYHISNVTTKLWERI---ISAGEQQNPQFSSVNWPIDGG----RNLAEEPAQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGIFQ-TDCDHNESFNQSNDEEWPPFRKVGCFDPYSDDPRLGIQKIALCKYSGK-MLVAGTAGQVLVMDLNDEKVEHTINVATVDLLQEREGFTWKGHDRLTPRNGSLFFQPGFQTITLVQCMPPAAVTAVALHSEWN-----LVAFGTSHGFGLFDYHRRSPVLA-----RCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRPNTGSPP--SRLQEANAQLAEQAGPHDLDIAPVQRRIEPRSADDSLSGVVRCLYFADTFLRDAIHHGP-----TMWAGTNSGSVFAYALEVPSREKLSDRSAEAVLGKEIQLMHRAPVVSIAVLDGRG--NPLPEPFEVSQDLAKAPDMQGTHSVLISSEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFTS--ATSDDYSENCLACLTNLG 881
BLAST of Protein lethal(2) giant larvae vs. Ensembl Xenopus
Match: LLGL1 (LLGL1, scribble cell polarity complex component [Source:NCBI gene;Acc:100486472]) HSP 1 Score: 213.386 bits (542), Expect = 4.571e-56 Identity = 224/947 (23.65%), Postives = 395/947 (41.71%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGS---LIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVID----RDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWK-RYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI------DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + +D L ++ I +K G +KI+G PGV ++ + + + F+PG ++L DN + LW EL + D S+L + T S ++ GS +V + L+ + T G Q+P+ + + +D I+ LP + + V + P R +LIGY G ++++ + V+ L L ++ W R + SS H DG + W +S + S + K C+ I+ + ++ I+FSGG+PR+ Y + +TI+ L + LD TS+++DF T+ DDN + V + +DL WP + PYL LH+S IT +S V + ++++ + +++ S +WPI G RN +E Q LL+ GH DGT+ FW G ++ + + ++ +F+ D H + +DE P R+ G FDP DD RL IQ L Y+GK +L+ G GQ+++ + K E ++ VDL F WKG GS+ FQ + + PP+ +TA+ + + N ++A GT HG + + + + CT+ N + E L + +++ R ++ P SR N + + ++ +R IE R D + G++R + + ++ +GP ++AG G + + + L + L K+ Q HRAP++ +L + L E + DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ T+ + ++ L C TN G
Sbjct: 48 QPSSLAFDPLLRIMAIGAKSGAVKIYGAPGVEFTGLHKDTATVTQMHFLPGQGRLLSLLDDNTMHLW-------ELQQKDGSSHL----------------------------------EETRSFLLPGKPGSPPSFTRVTVILITASCEVAGLGTEGGGVYFIQIPSLKLLEEKTLLQDEIVKSLPEEYRCGKTLGPVESLQEHPCQRGKILIGYSRGLVVLWDQEGRKVEHLFLGNQQLESVFW---------------GRKGTSFISS------HSDGGYMVWEADSDSSTTSQPAL-VTSSFAKGVLCVAIAPDCSSVSFIRNPYIIFSGGMPRASYGDRHCVTILQGQNL---------VTLDFTSRVVDFFTVCPLKSEDDNPTALVVLVEEELVV----IDLQTPGWPTV--PTPYLAPLHSSAITCAYHISNVTTKLWERIIS-AGEQQNPQFSSVNWPIDGG----RNLAEEPAQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGIFQ-TDCDHNESFNQSNDEEWPPFRKVGCFDPYSDDPRLGIQKIALCKYSGK-MLVAGTAGQVLVMDLNDEKVEHTINVATVDLLQEREGFTWKGHDRLTPRNGSLFFQPGFQTITLVQCMPPAAVTAVALHSEWN-----LVAFGTSHGFGLFDYHRRSPV--------CTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRPNTGSPP--SRLQEANAQLAEQAGPHDLDIAPVQRRIEPRSADDSLSGVVRCLYFADTFLRDAIHHGP-----TMWAGTNSGSVFAYALEVPSREKLSDRSAEAVLGKEIQLMHRAPVVSIAVLDGRG--NPLPEPFEVSQDLAKAPDMQGTHSVLISSEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFTS--ATSDDYSENCLACLTNLG 884
BLAST of Protein lethal(2) giant larvae vs. Ensembl Xenopus
Match: llgl2 (LLGL2, scribble cell polarity complex component [Source:NCBI gene;Acc:548396]) HSP 1 Score: 211.846 bits (538), Expect = 1.604e-55 Identity = 234/950 (24.63%), Postives = 410/950 (43.16%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEV---NDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYN-VQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQI-FSPYKKDQKCLPISKILW---KRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEY-----LLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD---VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCT------VPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + Y LSL+ I ++ G +K++G PGV + + + + I FIP VT+ DN L LW D +S L + + ++T I+V + + +G GS+ ++L L++ ++ + + + LP +R ++V + P + LLIGY G + ++ V+ SV + L K L + WC ++ SCH DG W + + + ++ + P++ C ISKI W +R + Y +VF GG+P + Y + I++++ N+ D TS++ID I + D S EY LLVL EEE ++DL WP++ + PYL LH S IT +S + ++++ + K++ S WPI G Q DLL+ GH DGT+ FW G C++ + + + S+F+ + + N S E++E PLR+ G FDP DD RL IQ I+ Y+G +L + G GQ+++ + E H++D VDL ++WKG + E ++ FQ + PP+ +T+L + + + ++A GT HG + ++ + A T H + P + + S + SL + + R R ++ K P R + + N + + L E E+ +R IE R + + G +R++ + ++ + P +L+AG GG + F + K+ Q HRAP++ +L S L E +A DL P+ + H L+V +EEQ +++ P + K K+++TA DG R++ ++ + ++ +++ L TN G
Sbjct: 34 QPSALGYSDCLSLMAIGTRSGALKVYGSPGVEFMGLHDENNSVTKISFIPDQCQLVTVLDDNSLHLW-------SFPHHDGVSELQ----------EEKKFTLRGPPGSPPSVTQIKVLLPHSSGEKLYVGTEGGSVFILELPSLRVLEE--------------------KTVGHEAALQGLPDEYSSRRAFESVEALQENPRNPDQLLIGYSRGMMVTWDLVKGRSVQYFL-GKQQLENVFWC---------------------RDGKQIVSCHSDGGYNQWEVSNELVQVSPKESKVPYGPFR----CKAISKITWHTTRRSRSPY-VVFQGGMPMASYGDRHIISVVHG---------NQQTAFDFTSRIIDHVVIANPDP-SAEYDDPRALLVLVEEELVMIDLQSPGWPVI--QCPYLISLHCSAITCSHHISSIPLKLWERIIS-AGRKQNTQYSNMPWPIDGGVNLAPAPP--QRDLLLTGHEDGTVRFWD-ASGICLQLMYKMSTVSVFQTESDHNDNVNSNEEEEWPPLRKVGSFDPYSDDPRLGIQKIYMCKYSG-YLSVAGTAGQVLVMELNDEAAE-HVVDETLVDLLQEQEGYRWKGHERLHAREDPVRFPPGFQPFALVQCQPPAAVTSLALHSE-----WRLLAFGTSHGFGLYDFQQKRQVMAKC-TLHASDQMALEGPLSRVKSLKKSLRQSFRRIRRSQVNK-----------------RRPGPDR-VQEANARFEQEALQEMELAPVQRRIEARSAEDSFTGFVRTLYFADTYLRDSSRHTP-----SLWAGTNGGTVYAFSLRVPPTERRMEEAVAATQAKEIQLMHRAPVVGILVLDGHS--VPLPEPLEAAHDLSKSPDMQGSHQLLVTSEEQFKVFTLPKVSSKLKLKLTATDGCRVRKMTVCTYGS--CKSEEHSENHLTILTNLG 868
BLAST of Protein lethal(2) giant larvae vs. Ensembl Xenopus
Match: llgl2 (LLGL2, scribble cell polarity complex component [Source:NCBI gene;Acc:548396]) HSP 1 Score: 211.846 bits (538), Expect = 1.722e-55 Identity = 237/950 (24.95%), Postives = 412/950 (43.37%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEV---NDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYN-VQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQI-FSPYKKDQKCLPISKILW---KRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEY-----LLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD---VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCT------VPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + Y LSL+ I ++ G +K++G PGV + + + + I FIP VT+ DN L LW D +S L + + ++T I+V + + +G GS+ ++L L++ ++ KTV + + LP +R ++V + P + LLIGY G + ++ V+ SV + L K L + WC ++ SCH DG W + + + ++ + P++ C ISKI W +R + Y +VF GG+P + Y + I++++ N+ D TS++ID I + D S EY LLVL EEE ++DL WP++ + PYL LH S IT +S + ++++ + K++ S WPI G Q DLL+ GH DGT+ FW G C++ + + + S+F+ + + N S E++E PLR+ G FDP DD RL IQ I+ Y+G +L + G GQ+++ + E H++D VDL ++WKG + E ++ FQ + PP+ +T+L + + + ++A GT HG + ++ + A T H + P + + S + SL + + R R ++ K P R + + N + + L E E+ +R IE R + + G +R++ + ++ + P +L+AG GG + F + K+ Q HRAP++ +L S L E +A DL P+ + H L+V +EEQ +++ P + K K+++TA DG R++ ++ + ++ +++ L TN G
Sbjct: 34 QPSALGYSDCLSLMAIGTRSGALKVYGSPGVEFMGLHDENNSVTKISFIPDQCQLVTVLDDNSLHLW-------SFPHHDGVSELQ----------EEKKFTLRGPPGSPPSVTQIKVLLPHSSGEKLYVGTEGGSVFILELPSLRVLEE----KTV----------------GHEAALQGLPDEYSSRRAFESVEALQENPRNPDQLLIGYSRGMMVTWDLVKGRSVQYFL-GKQQLENVFWC---------------------RDGKQIVSCHSDGGYNQWEVSNELVQVSPKESKVPYGPFR----CKAISKITWHTTRRSRSPY-VVFQGGMPMASYGDRHIISVVHG---------NQQTAFDFTSRIIDHVVIANPDP-SAEYDDPRALLVLVEEELVMIDLQSPGWPVI--QCPYLISLHCSAITCSHHISSIPLKLWERIIS-AGRKQNTQYSNMPWPIDGGVNLAPAPP--QRDLLLTGHEDGTVRFWD-ASGICLQLMYKMSTVSVFQTESDHNDNVNSNEEEEWPPLRKVGSFDPYSDDPRLGIQKIYMCKYSG-YLSVAGTAGQVLVMELNDEAAE-HVVDETLVDLLQEQEGYRWKGHERLHAREDPVRFPPGFQPFALVQCQPPAAVTSLALHSE-----WRLLAFGTSHGFGLYDFQQKRQVMAKC-TLHASDQMALEGPLSRVKSLKKSLRQSFRRIRRSQVNK-----------------RRPGPDR-VQEANARFEQEALQEMELAPVQRRIEARSAEDSFTGFVRTLYFADTYLRDSSRHTP-----SLWAGTNGGTVYAFSLRVPPTERRMEEAVAATQAKEIQLMHRAPVVGILVLDGHS--VPLPEPLEAAHDLSKSPDMQGSHQLLVTSEEQFKVFTLPKVSSKLKLKLTATDGCRVRKMTVCTYGS--CKSEEHSENHLTILTNLG 868
BLAST of Protein lethal(2) giant larvae vs. Ensembl Xenopus
Match: LLGL1 (LLGL1, scribble cell polarity complex component [Source:NCBI gene;Acc:100486472]) HSP 1 Score: 208.379 bits (529), Expect = 1.674e-54 Identity = 229/949 (24.13%), Postives = 398/949 (41.94%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGS---LIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVID----RDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI---DDNDSGSV-----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + +D L ++ I +K G +KI+G PGV ++ + + + F+PG ++L DN + LW EL + D S+L + T S ++ GS +V + L+ + T G Q+P+ + + +D I+ LP + + V + P R +LIGY G ++++ + V+ L L ++ W R + SS H DG + W +S S + + L S R + I+FSGG+PR+ Y + +TI+ L + LD TS+++DF T+ D+G+ L+VL EEE ++DL WP + PYL LH+S IT +S V + ++++ + +++ S +WPI G RN +E Q LL+ GH DGT+ FW G ++ + + ++ +F+ D H + +DE P R+ G FDP DD RL IQ L Y+GK +L+ G GQ+++ + K E ++ VDL F WKG GS+ FQ + + PP+ +TA+ + + N ++A GT HG + + + + A CT+ N + E L + +++ R ++ P SR N + + ++ +R IE R D + G++R + + ++ +GP ++AG G + + + L + L K+ Q HRAP++ +L + L E + DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ T+ + ++ L C TN G
Sbjct: 30 QPSSLAFDPLLRIMAIGAKSGAVKIYGAPGVEFTGLHKDTATVTQMHFLPGQGRLLSLLDDNTMHLW-------ELQQKDGSSHL----------------------------------EETRSFLLPGKPGSPPSFTRVTVILITASCEVAGLGTEGGGVYFIQIPSLKLLEEKTLLQDEIVKSLPEEYRCGKTLGPVESLQEHPCQRGKILIGYSRGLVVLWDQEGRKVEHLFLGNQQLESVFW---------------GRKGTSFISS------HSDGGYMVWEADSDS-----------STTSQPPEALVTSSFAKAREGLLNPYIIFSGGMPRASYGDRHCVTILQGQNL---------VTLDFTSRVVDFFTVCPLKSEDAGACFINNPTALVVLVEEELVVIDLQTPGWPTVP--TPYLAPLHSSAITCAYHISNVTTKLWERIIS-AGEQQNPQFSSVNWPIDGG----RNLAEEPAQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGIFQ-TDCDHNESFNQSNDEEWPPFRKVGCFDPYSDDPRLGIQKIALCKYSGK-MLVAGTAGQVLVMDLNDEKVEHTINVATVDLLQEREGFTWKGHDRLTPRNGSLFFQPGFQTITLVQCMPPAAVTAVALHSEWN-----LVAFGTSHGFGLFDYHRRSPVLA-----RCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRPNTGSPP--SRLQEANAQLAEQAGPHDLDIAPVQRRIEPRSADDSLSGVVRCLYFADTFLRDAIHHGP-----TMWAGTNSGSVFAYALEVPSREKLSDRSAEAVLGKEIQLMHRAPVVSIAVLDGRG--NPLPEPFEVSQDLAKAPDMQGTHSVLISSEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFTS--ATSDDYSENCLACLTNLG 865
BLAST of Protein lethal(2) giant larvae vs. Ensembl Mouse
Match: Llgl2 (LLGL2 scribble cell polarity complex component [Source:MGI Symbol;Acc:MGI:1918843]) HSP 1 Score: 233.802 bits (595), Expect = 9.809e-63 Identity = 223/925 (24.11%), Postives = 399/925 (43.14%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDR----DRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKD-SVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQI-FSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDR 2946
+PS + Y L +L I ++ G +K++G PGV + + + + I F+PG VTL DN L LW + +EL + + + +A +A +V + I+ + SG +LL + ++ N V Q+P + DR D ++ LP +++R + + V + P +LIGY G +I+++Q ++ LS++ NA SW +D ++ +CH DGS W + ++ L I + P+ C I+KI W +Q +F GG+PR+ Y + I++++N + D TS++IDFT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + N ++ +DE PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E + ++ DL ++WKG + G + + FQ + + PP+ +T+L + + + ++A GT HG + + + CT+ + + E L + +++ R + P+ N K R L E+ +R IE R + + G +R++ + ++ + P +L+AG GG + F + P+ K+ Q HRAP++ +L + L E + DL P+ + H L+V++EEQ +++ P + K K+++TA +G R++ + F R
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENNAVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAA---------------------PSATQVTE-----ILPHSSG-------ELLYLGTESGNVFVV-------QLPGFRTLHDRTICSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRALSHFLSSQQLENA-SW------QRDGCLIV---------------TCHSDGSHCQWPVSSDTQNPEPLRSSIPYGPFP----CKAITKIFWLTTRQGLPFTIFQGGMPRASYGDRHCISVVHN---------GQQTAFDFTSRVIDFTVLSEADPAAAFDDPYALVVLAEEELVVIDLQTPGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNSHFSTMEWPIDGGTSLAPPPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPSENLIAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVCFEAGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGFGLFDHQQRRQ-----VFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSHKRRPGG--PTGEAQAQAVNIKAERTGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLRDSSRHCP-----SLWAGTNGGTVYAFSLRVPPAERRTDEPVRAEQAKEIQLMHRAPVVGILVLDGHN--VPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVGVAHFGSCR 857
BLAST of Protein lethal(2) giant larvae vs. Ensembl Mouse
Match: Llgl2 (LLGL2 scribble cell polarity complex component [Source:MGI Symbol;Acc:MGI:1918843]) HSP 1 Score: 208.764 bits (530), Expect = 1.271e-54 Identity = 171/665 (25.71%), Postives = 297/665 (44.66%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDR----DRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKD-SVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQI-FSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGL 2175
+PS + Y L +L I ++ G +K++G PGV + + + + I F+PG VTL DN L LW + +EL + + + +A +A +V + I+ + SG +LL + ++ N V Q+P + DR D ++ LP +++R + + V + P +LIGY G +I+++Q ++ LS++ NA SW +D ++ +CH DGS W + ++ L I + P+ C I+KI W +Q +F GG+PR+ Y + I++++N + D TS++IDFT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + N ++ +DE PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E + ++ DL ++WKG + G + + FQ + + PP+ +T+L + + + ++A GT HG
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENNAVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAA---------------------PSATQVTE-----ILPHSSG-------ELLYLGTESGNVFVV-------QLPGFRTLHDRTICSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRALSHFLSSQQLENA-SW------QRDGCLIV---------------TCHSDGSHCQWPVSSDTQNPEPLRSSIPYGPFP----CKAITKIFWLTTRQGLPFTIFQGGMPRASYGDRHCISVVHN---------GQQTAFDFTSRVIDFTVLSEADPAAAFDDPYALVVLAEEELVVIDLQTPGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNSHFSTMEWPIDGGTSLAPPPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPSENLIAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVCFEAGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGF 611 HSP 2 Score: 51.9878 bits (123), Expect = 5.018e-6 Identity = 38/160 (23.75%), Postives = 74/160 (46.25%), Query Frame = 1
Query: 2476 RPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDR 2946
R + + G +R++ + ++ + P +L+AG GG + F + P+ K+ Q HRAP++ +L + L E + DL P+ + H L+V++EEQ +++ P + K K+++TA +G R++ + F R
Sbjct: 729 RSAEDSFTGFVRTLYFADTYLRDSSRHCP-----SLWAGTNGGTVYAFSLRVPPAERRTDEPVRAEQAKEIQLMHRAPVVGILVLDGHN--VPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVGVAHFGSCR 881
BLAST of Protein lethal(2) giant larvae vs. Ensembl Mouse
Match: Llgl1 (LLGL1 scribble cell polarity complex component [Source:MGI Symbol;Acc:MGI:102682]) HSP 1 Score: 192.586 bits (488), Expect = 1.881e-49 Identity = 195/741 (26.32%), Postives = 327/741 (44.13%), Query Frame = 1
Query: 850 LLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSD-WFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVS--YEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXD-RPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENI----LKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+LIGY G +I++ SVD + L +L W R+ SS H DGS W+ S L + +PY C I+KILW+ + D+ I+FSGG+PR+ Y + ++++ L + LD TS++IDF T+ +++ + + L VL EEE ++DL WP + PYL LH+S IT ++ V S W + ++ S WPI G RN E Q LL+ GH DGT+ FW G ++ + + ++ LF+ D H + ++ EDD P R+ G FDP DD RL IQ L YT + +++ G GQ+++ E E + +VDL F WKG + G + + FQ M + PP+ +TA+ + + + ++A GT HG + +++ + A CT+ P ++LA EG R K +S R + R + + P+ S L + N + + + + R D + G++R + + ++ +GP ++AG G + + + + L K+ Q HRAP++ +L L E +A DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ + +++ + L C TN G
Sbjct: 210 ILIGYSRGLLVIWSQATQSVDNVFLGNQQLESLCW---------------GRDGSSIISS------HSDGSYAIWSTDTGSPPTLQPTV-VTTPYGPF-PCKAINKILWRSCESGDHFIIFSGGMPRASYGDRHCVSVLRAETL---------VTLDFTSRVIDFFTVHSTQPEDECDNPQALAVLLEEELVVLDLQTPGWPAV--PAPYLAPLHSSAITCSAHVANVPSKLWARIVSAGEQQSPQPASSALSWPITGG----RNLAQEPSQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGLFQT-DCEHADSLAQAVEDDWPPFRKVGCFDPYSDDPRLGIQKVALCKYTAQ-MVVAGTAGQVLVLELSEVPAEHAVSVANVDLLQDREGFTWKGHERLNPHTGLLPWPAGFQPRMLIQCLPPAAVTAVTLHAE-----WSLVAFGTSHGFGLFDYQRKSPVLA-----RCTLHPNDSLAM------EGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRTPAASSKLQEANAQLAEQTCPHDLEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDATHHGP-----TMWAGTNSGSVFAYALEVPAATAGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRG--RPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFAS--VMSEDYAETCLACLTNLG 884
BLAST of Protein lethal(2) giant larvae vs. Ensembl Mouse
Match: Llgl1 (LLGL1 scribble cell polarity complex component [Source:MGI Symbol;Acc:MGI:102682]) HSP 1 Score: 192.2 bits (487), Expect = 2.403e-49 Identity = 195/741 (26.32%), Postives = 327/741 (44.13%), Query Frame = 1
Query: 850 LLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQ-DYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSD-WFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVS--YEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXD-RPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENI----LKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+LIGY G +I++ SVD + L +L W R+ SS H DGS W+ S L + +PY C I+KILW+ + D+ I+FSGG+PR+ Y + ++++ L + LD TS++IDF T+ +++ + + L VL EEE ++DL WP + PYL LH+S IT ++ V S W + ++ S WPI G RN E Q LL+ GH DGT+ FW G ++ + + ++ LF+ D H + ++ EDD P R+ G FDP DD RL IQ L YT + +++ G GQ+++ E E + +VDL F WKG + G + + FQ M + PP+ +TA+ + + + ++A GT HG + +++ + A CT+ P ++LA EG R K +S R + R + + P+ S L + N + + + + R D + G++R + + ++ +GP ++AG G + + + + L K+ Q HRAP++ +L L E +A DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ + +++ + L C TN G
Sbjct: 210 ILIGYSRGLLVIWSQATQSVDNVFLGNQQLESLCW---------------GRDGSSIISS------HSDGSYAIWSTDTGSPPTLQPTV-VTTPYGP-FPCKAINKILWRSCESGDHFIIFSGGMPRASYGDRHCVSVLRAETL---------VTLDFTSRVIDFFTVHSTQPEDECDNPQALAVLLEEELVVLDLQTPGWPAV--PAPYLAPLHSSAITCSAHVANVPSKLWARIVSAGEQQSPQPASSALSWPITGG----RNLAQEPSQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGLFQT-DCEHADSLAQAVEDDWPPFRKVGCFDPYSDDPRLGIQKVALCKYTAQ-MVVAGTAGQVLVLELSEVPAEHAVSVANVDLLQDREGFTWKGHERLNPHTGLLPWPAGFQPRMLIQCLPPAAVTAVTLHAE-----WSLVAFGTSHGFGLFDYQRKSPVLA-----RCTLHPNDSLAM------EGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRTPAASSKLQEANAQLAEQTCPHDLEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDATHHGP-----TMWAGTNSGSVFAYALEVPAATAGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRG--RPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFAS--VMSEDYAETCLACLTNLG 884
BLAST of Protein lethal(2) giant larvae vs. Ensembl Mouse
Match: Stxbp5l (syntaxin binding protein 5-like [Source:MGI Symbol;Acc:MGI:2443815]) HSP 1 Score: 108.612 bits (270), Expect = 2.627e-23 Identity = 84/405 (20.74%), Postives = 173/405 (42.72%), Query Frame = 1
Query: 811 VIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQK-------CLPISKILWKRYK-QDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDD----NDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDEIPLRRTGQFDPCC---DDNRLAIQLIHYT--GKHLLIGGYGGQIVLWGFQENKYEKHLLDVDL 1974
V+H+S P LLIGY +G + ++++ + + ++++ W ++ + H DGS+ WNL S FQ P+ K Q+ C PI K+ +K + + I+FSGGL + ++TIM+ + VL++ +++F T+ + N+ + VL E++ +VDLT+ ++PI + PY +H SP+T + ++ D L + + S +WP+ G A + +++I GH DGTI FW ++ + +K+S +F+ ++ G+ C +++ A+Q+I++ + + G ++++ F ++ ++ +++
Sbjct: 210 VVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDW---------------------HHEGKQFMCSHSDGSLTLWNLKSPSR-----PFQTTVPHGKSQREGRKSESCKPILKVEYKTCRNSEPFIIFSGGLSYDKACRRPSLTIMHGKAIT---------VLEMDHPIVEFLTLCETPYPNEFQEPYAVAVLLEKDLIVVDLTQTNFPIFEN--PYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSNKEWPVSGGAWNLGAQTY--PEIIITGHADGTIKFWD-ASAMTLQMLYKLKTSKVFEK------------------QKAGEGKQTCELVEEDPFAVQMIYWCPESRIFCVSGVSAYVIIYKFSRHEVTTEIVSLEV 556
BLAST of Protein lethal(2) giant larvae vs. UniProt/SwissProt
Match: sp|Q6P1M3|L2GL2_HUMAN (LLGL scribble cell polarity complex component 2 OS=Homo sapiens OX=9606 GN=LLGL2 PE=1 SV=2) HSP 1 Score: 241.891 bits (616), Expect = 1.551e-64 Identity = 232/921 (25.19%), Postives = 396/921 (43.00%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLN-EVSYEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPS-VSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDR 2946
+PS + Y L +L I ++ G IK++G PGV + + + + I +PG VTL DN L LW + +EL + D L A SA IT + + + +G SG++ V+L + + I D ++ +LP +++R + + V + P +LIGY G +I+++Q V + + L + W +D + L SCH DGS W P +S+ + PY C I++ILW +Q +F GG+PR+ Y + I++++ + + D TS++I FT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + + N ED+ PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E+ + ++ DL ++WKG + G ++ FQ + + PP+ +T+L + + + ++A GT HG + + + CT+ P + LA EG R K +S R R R + R HP+ + + K R L E+ +R IE R + + G +R++ + +K + P +L+AG GG + F + P+ K+ Q HRAP++ +L S L E + DL P+ + H L+V++EEQ +++ P + K K+++TA +G R++ S+ F R
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASEL-QEDESFTLRGPPGAAPSA---------------TQITVVLPHSSCELLYLGTESGNVFVVQLPAFRA--------------------LEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWW------QRDGRL---------------LVSCHSDGSYCQW--PVSSEAQQPEPLRSLVPYGPF-PCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIH---------DGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNAHFSTMEWPIDGGTSLTPAPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGFGLFDHQQRRQ-----VFVKCTLHPSDQLAL------EGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCP-----SLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHS--VPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRR 855
BLAST of Protein lethal(2) giant larvae vs. UniProt/SwissProt
Match: sp|Q3TJ91|L2GL2_MOUSE (LLGL scribble cell polarity complex component 2 OS=Mus musculus OX=10090 GN=Llgl2 PE=1 SV=2) HSP 1 Score: 212.231 bits (539), Expect = 5.992e-55 Identity = 202/845 (23.91%), Postives = 359/845 (42.49%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDR----DRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKD-SVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQI-FSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPIL 2715
+PS + Y L +L I ++ G +K++G PGV + + + + I F+PG VTL DN L LW + +EL + + + +A +A +V + I+ + SG +LL + ++ N V Q+P + DR D ++ LP +++R + + V + P +LIGY G +I+++Q ++ LS++ NA SW +D ++ +CH DGS W + ++ L I + P+ C I+KI W +Q +F GG+PR+ Y + I++++N + D TS++IDFT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + N ++ +DE PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E + ++ DL ++WKG + G + + FQ + + PP+ +T+L + + + ++A GT HG + + + CT+ + + E L + +++ R + P+ N K R L E+ +R IE R + + G +R++ + ++ + P +L+AG GG + F + P+ K+ Q HRAP++
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENNAVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAA---------------------PSATQVTE-----ILPHSSG-------ELLYLGTESGNVFVV-------QLPGFRTLHDRTICSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRALSHFLSSQQLENA-SW------QRDGCLIV---------------TCHSDGSHCQWPVSSDTQNPEPLRSSIPYGPFP----CKAITKIFWLTTRQGLPFTIFQGGMPRASYGDRHCISVVHN---------GQQTAFDFTSRVIDFTVLSEADPAAAFDDPYALVVLAEEELVVIDLQTPGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNSHFSTMEWPIDGGTSLAPPPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPSENLIAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVCFEAGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGFGLFDHQQRRQ-----VFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSHKRRPGG--PTGEAQAQAVNIKAERTGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLRDSSRHCP-----SLWAGTNGGTVYAFSLRVPPAERRTDEPVRAEQAKEIQLMHRAPVV 779
BLAST of Protein lethal(2) giant larvae vs. UniProt/SwissProt
Match: sp|Q7SZE3|L2GL2_DANRE (LLGL scribble cell polarity complex component 2 OS=Danio rerio OX=7955 GN=llgl2 PE=1 SV=1) HSP 1 Score: 211.075 bits (536), Expect = 1.537e-54 Identity = 237/957 (24.76%), Postives = 406/957 (42.42%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTN--ELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI--DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+ Y+ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W + + EL ++ + L+ A S +TA+ + +++G G + V++ + ++ N I + + +++P R +++V + P + + +LIGY G +++++ + L ++ W ++D + S H DGS W + PQ E + F C ISKI+ KQ ++FSGG+PR+ Y + I+++++ H LD TS++IDF I +N G L+VL EEE +VDL E WP++ + PYL LH S IT +S + ++++ ++ ++ + S WPI G + + D Q DLL+ GH DGT+ FW G C+ + + ++ +F AD E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + E+ + VDL F+WKG E + FQ + PP+ +TA+ + + + ++ GT HG + + N + CT+ P + +A EG R K +S R R R + R H + + L + N + L E E+ +R IE R D + GL+R++ + + + P +L+AG GG + + + P+ K+ Q HRAP++ +L + + L E + DL R P+ HL+V++EEQ +L+ P + K K+++TA DG R++ + F T + L+ TN G
Sbjct: 19 DLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFT-LSGPPGAIPSV---------------TRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENN--------------------ISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWW------MEDGESIL---------------SSHSDGSYCQWTVTGEDPQTEPEKQETPYGAFP-------CKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSKT---------HEALDFTSRIIDFFVIREGENHKGEPSALVVLVEEELVVVDLQTEGWPVI--QTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAH-QNTHYSRKPWPING-GKNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLYPMYKLSTAGVFHTDADPNDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVLFPPGFQPFALVQCQPPAVVTAIALHSE-----WKLVGFGTSHGFGLYDYNQRNN-----IMVKCTLNPSDQMAM------EGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNNAAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTP-----SLWAGTNGGAVFAYVLRVPPQERRAEDPVTAHAAKEIQLMHRAPVVGLVVLDGKG--APLPEPLEVAHDL--ARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGS---RTDEQLESCLVVLTNQG 867
BLAST of Protein lethal(2) giant larvae vs. UniProt/SwissProt
Match: sp|Q5RCX2|L2GL2_PONAB (LLGL scribble cell polarity complex component 2 OS=Pongo abelii OX=9601 GN=LLGL2 PE=2 SV=1) HSP 1 Score: 210.69 bits (535), Expect = 2.105e-54 Identity = 168/659 (25.49%), Postives = 287/659 (43.55%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSV----EYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHL--LDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGL 2175
+PS + Y L +L I ++ G IK++G PGV + + + I +PG VTL DN L LW + +EL + D L A SA IT + + + +G SG++ V+L + + I D ++ +LP +++R + + V + P +LIGY G +I+++Q V + + L + W +D ++ SCH DGS W P +S+ + PY C I+KILW +Q +F GG+PR+ Y + ++++ + + D TS++IDFT + + D + L+VL EEE ++DL WP + + PYL LH S IT +S + ++++ S +++ + S +WPI G Q DLL+ GH DGT+ FW G C++ + + + +F + + N ++ +DE PLR+ G FDP DD RL IQ L Y+G +L + G GQ+++ + E+ + ++ DL ++WKG + G ++ FQ + + PP+ +T+L + + + ++A GT HG
Sbjct: 34 QPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHRENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASEL-QEDESFTLRGPPGAAPSA---------------TQITVVLPHSSCELLYLGTESGNVFVVQLPAFRA--------------------LEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWW------QRDGRLLV---------------SCHSDGSYCQW--PMSSEAQQPEPLRSLVPYGPF-PCKAITKILWLTTRQGLPFTIFQGGMPRASYGDRHCTSVIH---------DGQQTAFDFTSRVIDFTVLTEADPAAAFDDPYALVVLAEEELVVIDLQTAGWPPV--QLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGS-RQNAHFSTMEWPIDGGTSLTPAPP--QRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPNENLSAHGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSG-YLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAHSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSE-----WRLVAFGTSHGF 611
BLAST of Protein lethal(2) giant larvae vs. UniProt/SwissProt
Match: sp|Q15334|L2GL1_HUMAN (Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3) HSP 1 Score: 185.652 bits (470), Expect = 1.773e-46 Identity = 185/741 (24.97%), Postives = 327/741 (44.13%), Query Frame = 1
Query: 850 LLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQD-YLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFS-DWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVS--YEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEK--HLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXD-RPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENI----LKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+LIGY G +I+N VD + L +L W R+ S + S H DGS W++ ++ F L + + C I+KILW+ + + I+FSGG+PR+ Y + ++++ L + LD TS++IDF T+ +++ + L VL EEE ++DL WP + PYL LH+S IT ++ V + + ++ + +S + WPI G RN E Q LL+ GH DGT+ FW G ++ + + ++ LF+ D H + ++ EDD P R+ G FDP DD RL +Q L YT + +++ G GQ+++ + E+ + +DL F WKG + G + + FQ + + PP+ +TA+ + + + ++A GT HG + +++ + A CT+ P ++LA EG R K +S R + R + + + S L + N + + + + R D + G++R + + ++ +GP ++AG G + + + + + L K+ Q HRAP++ +L L E +A DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L F+ + ++ + L C TN G
Sbjct: 211 ILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLCW---------------GRD------SSTVVSSHSDGSYAVWSV--DAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGHFIIFSGGMPRASYGDRHCVSVLRAETL---------VTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLEEELVVLDLQTPGWPAVP--APYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSSALSWPITGG----RNLAQEPSQRGLLLTGHEDGTVRFWD-ASGVALRPLYKLSTAGLFQT-DCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQ-MVVAGTAGQVLVLELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAAVTAVTLHTE-----WSLVAFGTSHGFGLFDYQRKSPVLA-----RCTLHPNDSLAM------EGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDGAHHGP-----TMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGKEVQLMHRAPVVAIAVLDGRG--RPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFAS--VACEDYAETCLACLTNLG 885
BLAST of Protein lethal(2) giant larvae vs. TrEMBL
Match: A0A087VX44 (Lethal2 giant larvae protein 2 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000060600 PE=4 SV=1) HSP 1 Score: 322.013 bits (824), Expect = 2.215e-88 Identity = 233/837 (27.84%), Postives = 369/837 (44.09%), Query Frame = 1
Query: 106 MTQSIFNSVRKL--NFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLP------QNSDEFLVLDFQIFS----PYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNS-----------------------CLDSSKANN------------------------------EHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNI-------SFSDWPIKGYAQKVRNDE----IWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFK------MADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQPFQ------HIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGY---------------VIIACGTLHGLVIVS-CPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRT 2304
M Q IF S R+L + + K + E +G YK + G +PS + YD L + +A++ G++ +FG PGV Y +G EI + F G +TL+ D+ + LW I + + I L+ V+ A S H + D + + I TA+ V+ SSI++G G++ ++ + KQ + NT+W MP+K +I R + + + R+ +DAV+ + RP LLIGY SG ++Y++Q + V LL + L A +WC + + P P ++ + + +GS+ W +P + E Q+ PY C ISK+ W + + +F+GG+PRS Y ++T++I+ S C S+ EH+ LDL S ++D + G V LL+L EEE +DL WP+L PYLNCLH S +T Y ++V + + L + + + S WPI+G RN+ + NDLLI GH +GT+ FW+ GGC +KI ++ + SLF+ A + H + P RR G FDP DD R AI++IH L++GG GQ+ +W K LDV + + F+WKG P + + S F + +++C PPS +T L + E ++ + V++ GT HG ++ E + +L H T+P N A +EA++GEGWARRRT
Sbjct: 1 MAQRIFQSFRRLPSQLTSVRKKQ-DTVEVVGSHYKINVCSNVGFPAKPSSLAYDQSLDVFALATRDGILYVFGKPGVVYYGSHKGALEIIKVLFFTGMGKLLTLSVDDMIYLWEIVSPNGNQPGLQNIGQLSGVSDALESKHLEVDPIGDITSHI----TALIVSSSNSSILVGTDQGNVAPIRRN--THVKQGVDQDE----NTMWIMPSKDKIITPHRALQSISPEKRTRLRLDAVVVLLERPSYPSQLLIGYSSGICLLYDLQGERVLALLPCQYELEAATWCGGSGLPVRGTVTNPTATPPHL--GTRVLTAYGNGSLGVWQIPLFATGPGLATELGTQTLQMMESPSMPYGPF-PCKLISKVFWLPSYEGGITIFTGGMPRSIYGNRNTVSILRGSNLDQAAAANLAAALRADSEGDADCERSTAGQEFYDGGANADILLPSGLVPGAPVHVFDSDAPEHVCLDLPSLVVDVCPLGPA-GGPVTGLLILCEEELIAIDLLTPGWPLLE--LPYLNCLHASSLTTYGLFTQVNPAFLEGLEAIGGGADAVGLVPRATGLSTRTWPIQGGELGRRNEVSEPVVPSNDLLITGHENGTLQFWRLAAGGCARKIFSLFTGSLFEGDFGPDAAGDTHQTCEEESEPWPPFRRAGLFDPFMDDVRAAIKVIHLVDSTLVVGGAAGQVSVWQLAPTKPTMATLDVPIAPEVPGFRWKGYAPLTLRRNQLNQPKRLAGASLFPMAVALCQ-PPSPVTCLSVCELSDFSAMDKSLQPSPQSSPTIGVLVGMGTAHGFALMHISASEGGFASHLLLHHSTIPSNAEALEEAAVGEGWARRRT 819 HSP 2 Score: 102.449 bits (254), Expect = 3.927e-18 Identity = 77/274 (28.10%), Postives = 130/274 (47.45%), Query Frame = 1
Query: 2473 DRPKDTANDGLIRSIRINVSLIKR------------KGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNEN------PDAGFDLDPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTK----EPLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNTRTLCP-YGICYSGQGQVTLFEII---SKTKTIGT 3216
DRP TAN L+R + L R + + L + FA GG F +N+ + S + LR Q Q QHRAPI+ ++ ++ L + + P HL+V++EEQVRL++ PS +L+ K R+TA DGFR+K G+++ F +L+ + N E TNNGGQ ++L+ L+R+D + + D++ +N + A A+ P G+ + GQ+ +F+++ ++ +GT
Sbjct: 936 DRPATTANTALVRCMAFGPPLHHRLRPPAAGITASTSATIETSQLLGSFFAATAGGATFVFA--LYTDNVRRPSHLALRQATQMQLQHRAPIVALRLIDTKTHCPLLTSSVYLPQFSSPLVPPHHHPLPPHLMVISEEQVRLFSLPSISLRQKARITAKDGFRIKTGNIMAFG--QLSNERNMGIYGVEFNCVFTNNGGQAVVLSVPYLRRRDTIALLGGADVLEINSIVFATAASTRPKVIAAPSLGVYQTAPGQLAIFDMVLAGQRSSALGT 1205
BLAST of Protein lethal(2) giant larvae vs. TrEMBL
Match: A0A068WQJ7 (Lethal2 giant larvae protein 2 OS=Echinococcus granulosus OX=6210 GN=EgrG_000060600 PE=4 SV=1) HSP 1 Score: 316.235 bits (809), Expect = 2.736e-86 Identity = 233/841 (27.71%), Postives = 371/841 (44.11%), Query Frame = 1
Query: 106 MTQSIFNSVRKL--NFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLP------QNSDEFLVLDFQIFS----PYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNS-----------------------CLDSSKANN------------------------------EHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCN-------ISFSDWPIKGYAQKVRNDE----IWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM---ADELHLNEVSYEDDE---IPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQPF----------QHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGY---------------VIIACGTLHGLVIVS-CPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRT 2304
M Q IF S R+L + + K + E +G YK + G +PS + YD L + +A++ G++ +FG PGV Y +G EI + F G +TL+ D+ + +W I + + I L+ V+ A S H + D + + I TA+ V+ SSI++G G++ ++ + KQ + NT+W MP+K +I R + + + R+ +DAV+ + RP LLIGY SG ++Y++Q + V LL + L A +WC + + P P ++ + + +GS+ W +P + E Q+ PY C ISK+ W + + +F+GG+PRS Y ++T++I+ S C S+ EH+ LDL S ++D + G V LL+L EEE +DL WP+L PYLNCLH S +T Y ++V + + L + + +S WPI+G RN+ + +DLLI GH +GT+ FW+ GGC +KI + + SLF+ D + + E++ P RR G FDP DD R AI++IH L++GG GQ+ +W K LDV + + F+WKG P Q + G+ S F + +++C PPS +T L E ++ + V++ GT HG ++ E + +L H T+P N A +EA++GEGWARRRT
Sbjct: 1 MAQRIFQSFRRLPSQLTSVRKKQ-DTVEVVGSHYKINVCSNVGFPAKPSSLAYDQSLDIFALATRDGILYVFGKPGVVYYGSHKGALEIIKVLFFTGMGKLLTLSVDDIIYVWEIVSPNGNQPGLQNIGQLSGVSDALESKHLEVDPIGDITSHI----TALIVSSSNSSILVGTDQGNVAPIRRN--THVKQGVDQDE----NTMWIMPSKDKIITPHRALQSISPEKRTRLRLDAVVVLLERPSYPSQLLIGYSSGICLLYDLQGERVLALLPCQYELEAATWCGGSGLPVRGAVANPTATPPHL--GTRVLTAYGNGSLGVWQIPLFATGPGLATELGTQTLQMMESPSMPYGPF-PCKLISKVFWLPSHEGGITIFTGGMPRSIYGDRNTVSILRGSNLDQAAAANLAAALRADSEGDADCERSTAGQEFYDGGANADILLPSGLVPGAPVHVFDSDAPEHVCLDLPSLVVDVCPLGPA-GGPVTGLLILCEEELIAIDLLTPGWPLLE--LPYLNCLHASSLTTYGLFTQVNPAFLEGLEAIGGGADAVGPVPRATGLSTRTWPIQGGELGRRNEVSEPVVPSDDLLITGHENGTLQFWRLAAGGCARKIFCLFTGSLFEGDFGPDAVGDTHRACEEESEPWPPFRRVGLFDPFMDDVRAAIKVIHLVDSTLVVGGAAGQVSVWQLAPTKPTMATLDVPVAPEVPGFRWKGYAPLTLRRNQLDQPQRLAGA----SLFPMAVALCQ-PPSPVTCLSACELSDFSAMDKSLQPSPQPSPTIGVLVGMGTAHGFALMHISASEGGFASHLLLHHSTIPSNAEALEEAAVGEGWARRRT 819 HSP 2 Score: 105.531 bits (262), Expect = 5.237e-19 Identity = 81/274 (29.56%), Postives = 134/274 (48.91%), Query Frame = 1
Query: 2473 DRPKDTANDGLIRSIRINVSLIKR------------KGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNEN---PDAGFDL---DPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLI---CA-TNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNTRTLCP-YGICYSGQGQVTLFEII---SKTKTIGT 3216
DRP TAN L+R + L R + + L + FA GG F +N+ + S + LR Q Q QHRAPI+ ++ ++ L + P L + P HL+V++EEQVRL++ PS +L+ K R+TA DGFR+K G+++ F +L+ + N I C TNNGGQ ++L+ L+R+D + + D++ +N + A A+ T P G+ + GQ+ +F+++ ++ +GT
Sbjct: 936 DRPAATANTALVRCMAFGPPLHHRLRPPAAGITASTSATIETSQLLGSFFAATAGGATFVFA--LYTDNVRRPSHLALRQATQMQLQHRAPIVALRLIDTKTHCPLLTSSVYLPQFSSPLVPSHHHPLPPHLMVISEEQVRLFSLPSISLRQKARITAKDGFRIKTGNIMAFG--QLSNERNMGIYGIEFNCVFTNNGGQAVVLSVPYLRRRDTIALLGGADVLEINSIVFATAASTRPKVTAAPSLGVYQTAPGQLAIFDMVLAGQRSSALGT 1205
BLAST of Protein lethal(2) giant larvae vs. TrEMBL
Match: A0A0X3Q0S6 (LLGL domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR123718 PE=4 SV=1) HSP 1 Score: 311.612 bits (797), Expect = 1.341e-84 Identity = 225/846 (26.60%), Postives = 374/846 (44.21%), Query Frame = 1
Query: 106 MTQSIFNSVRKL-NFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSA--RTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLP-------QNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLD----------------------------LTSQLIDFTTIDDNDSGSVEYL------------------------LVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSS---------NKEDCNISFSDWPIKG---------------YAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLF--KMADELHLNEVSYEDDE----IPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQP--FQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILE--------------DNNCNGYVIIACGTLHGLVIVS-CPKETNLEA----LVLTTHCTVPRNTLASQEASLGEGWARRRT 2304
M Q IF S R+L + + + E +G YK + G +P+ + YDH L++ + +K GLI ++G PG+ Y + EI N+ F+ GT +TL+ + + +W + + V + +L+ V + + N + ++TA+ N +SI G +G + L + N + +P + +W +PT + I R++ +P ++R+ +DAV+ +S RPG LLIGY SG S+IY++ D V +L + L A +WC + N P PQ +L + H DGS+ W +P + L ++ PY C ISK+ W + + +F+GG+PRS Y +ST++++ S LD + A N + L S L+ + D+ + E++ L+L EEE VDL WP+L PYL+CLH S I+AY + V + + ++L+ ++ + + S WP++G + + + DLL+ GH +GT+ FW+ G GGC +K+ T+ + SLF + + + DDE P RR G FDP DD R A++ I L++GG GQ+ +W F + K +DV + + F+WKG P + + S G + + PP+QIT+L + E + G V++ GT HG +V P+ ++ A ++ T+P N+ A +EA++GEGWARRRT
Sbjct: 1 MAQRIFQSFRRLPGQLSAMRRKQDSIEVVGNHYKINMFSNVGFPAKPASLAYDHALNIFALVTKDGLIYVYGKPGIVYVGSHQNASEIINVMFLSGTGKLLTLSDRDDIYIWQLESEDGTQPCVKQVCHLSAVTQGLEQRRVVVDQNSTENTFADVASHVTALYANTNGTSIYFGTENGHVA------LIHKNAQNKHGNLPHCHEVWTLPTYDESISPQRVLQTIPSEKRSRLRLDAVVVLSERPGFVGQLLIGYNSGLSLIYDLHADCVLAILPWQYGLEAATWCGGSGLPLRNASSRPMMQSPQL--GTRLLTAHADGSLGVWRVPVFSRIMGDQPAQTLSMEEAPSMPYGPF-PCKLISKVFWVPSHRGGITIFAGGMPRSTYGDRSTVSLLRGSNLDQAAAANLAAAVRLAHADGDLEDEDEEEEEADFEDEDQQNLLASGLVPGAPVHVFDADAPEHVCLDLPSPLVDVCPLGPAGGPATGVLILCEEELVAVDLLTPGWPLL--TLPYLSCLHTSAISAYNLFTHVNAVFLERLDAVAGCGKGDALGLGRRETGYSKRPWPVQGGQCILPGSGSPSRGALSIDPAHSLVTSTDLLVTGHENGTVNFWRLGPGGCARKVFTLYTGSLFDGEFGPDAGGDARRNGDDENDPWPPFRRAGLFDPFMDDPRAAVKCIQLVENTLVVGGAAGQVTVWQFADEKPVLQTVDVPIVQEIPGFRWKGHAPLKLRALGPSRSPGMSLYPVGIALTQPPAQITSLAVCELPATTAATPVAASPEPAKPGVVLVGFGTPHGFGLVHWAPRSSDGGADSPPTLILAQSTIPLNSEALEEAAVGEGWARRRT 835 HSP 2 Score: 109.383 bits (272), Expect = 3.121e-20 Identity = 73/270 (27.04%), Postives = 129/270 (47.78%), Query Frame = 1
Query: 2473 DRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSP--INLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSD----------------DRLTTQNNTKEPL------------ICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNTRTLCPYGICYSGQGQVTLFEII 3192
DRP +TA+ ++R + +L + + G + + FA GG + Y++ N P + +R + HRAP++ ++ ++ + + + + N P HLVV++EEQVRL++ PS L+ K+R+TA DGFR+K S++ F D T+ + P+ + TNNGGQ ++L+ L+RKD + + DL+A+N ++ A NA + T G+ GQ+ LF+++
Sbjct: 942 DRPAETASTAVVRCVAFGPALHRIRAPAGTAVLVGSFFASTTGGA----TNVYALFADRANQPSQLAVRHASELVLHHRAPVIALRLIDTKTHIPFSPNSIGSSSLVSSNSPPPHLVVVSEEQVRLFSLPSLHLRQKVRITAKDGFRIKAASIVTFQQTAQFDGCFDKMAGSLGDGSTSHHQPSPPIGLVRGSLGPEFGLVFTNNGGQAVVLSIPYLRRKDTIALLGPLDLLAVNSVAFAANATSACTALAPSLGVYQLAHGQLALFDVV 1207
BLAST of Protein lethal(2) giant larvae vs. TrEMBL
Match: W6V053 (Lethal(2) giant larvae protein OS=Echinococcus granulosus OX=6210 GN=EGR_05828 PE=4 SV=1) HSP 1 Score: 309.301 bits (791), Expect = 5.265e-84 Identity = 233/841 (27.71%), Postives = 369/841 (43.88%), Query Frame = 1
Query: 106 MTQSIFNSVRKL--NFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLP------QNSDEFLVLDFQIFS----PYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNS-----------------------CLDSSKANN------------------------------EHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCN-------ISFSDWPIKGYAQKVRNDE----IWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM---ADELHLNEVSYEDDE---IPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQPF----------QHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGY---------------VIIACGTLHGLVIVS-CPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRT 2304
M Q IF S R+L + + K + E +G YK + G +PS + YD L + +A++ G+ FG PGV Y +G EI + F G +TL+ D+ + +W I + + I L+ V+ A S H + D + + I TA+ V+ SSI++G G++ ++ + KQ + NT+W MP+K +I R + + + R+ +DAV+ + RP LLIGY SG ++Y++Q + V LL + L A +WC + + P P ++ + + +GS+ W +P + E Q+ PY C ISK+ W + + +F+GG+PRS Y ++T++I+ S C S+ EH+ LDL S ++D + G V LL+L EEE +DL WP+L PYLNCLH S +T Y ++V + + L + + +S WPI+G RN+ + +DLLI GH +GT+ FW+ GGC +KI + + SLF+ D + + E++ P RR G FDP DD R AI++IH L++GG GQ+ +W K LDV + + F+WKG P Q + G+ S F + +++C PPS +T L E ++ + V++ GT HG ++ E + +L H T+P N A +EA++GEGWARRRT
Sbjct: 1 MAQRIFQSFRRLPSQLTSVRKKQ-DTVEVVGSHYKINVCSNVGFPAKPSSLAYDQSLDIFALATRDGIF--FGKPGVVYYGSHKGALEIIKVLFFTGMGKLLTLSVDDIIYVWEIVSPNGNQPGLQNIGQLSGVSDALESKHLEVDPIGDITSHI----TALIVSSSNSSILVGTDQGNVAPIRRN--THVKQGVDQDE----NTMWIMPSKDKIITPHRALQSISPEKRTRLRLDAVVVLLERPSYPSQLLIGYSSGICLLYDLQGERVLALLPCQYELEAATWCGGSGLPVRGAVANPTATPPHL--GTRVLTAYGNGSLGVWQIPLFATGPGLATELGTQTLQMMESPSMPYGPF-PCKLISKVFWLPSHEGGITIFTGGMPRSIYGDRNTVSILRGSNLDQAAAANLAAALRADSEGDADCERSTAGQEFYDGGANADILLPSGLVPGAPVHVFDSDAPEHVCLDLPSLVVDVCPLGPA-GGPVTGLLILCEEELIAIDLLTPGWPLLE--LPYLNCLHASSLTTYGLFTQVNPAFLEGLEAIGGGADAVGPVPRATGLSTRTWPIQGGELGRRNEVSEPVVPSDDLLITGHENGTLQFWRLAAGGCARKIFCLFTGSLFEGDFGPDAVGDTHRACEEESEPWPPFRRVGLFDPFMDDVRAAIKVIHLVDSTLVVGGAAGQVSVWQLAPTKPTMATLDVPVAPEVPGFRWKGYAPLTLRRNQLDQPQRLAGA----SLFPMAVALCQ-PPSPVTCLSACELSDFSAMDKSLQPSPQPSPTIGVLVGMGTAHGFALMHISASEGGFASHLLLHHSTIPSNAEALEEAAVGEGWARRRT 817 HSP 2 Score: 105.145 bits (261), Expect = 6.046e-19 Identity = 80/274 (29.20%), Postives = 133/274 (48.54%), Query Frame = 1
Query: 2473 DRPKDTANDGLIRSIRINVSLIKR------------KGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNEN---PDAGFDL---DPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTK----EPLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNTRTLCP-YGICYSGQGQVTLFEII---SKTKTIGT 3216
DRP TAN L+R + L R + + L + FA GG F +N+ + S + LR Q Q QHRAPI+ ++ ++ L + P L + P HL+V++EEQVRL++ PS +L+ K R+TA DGFR+K G+++ F +L+ + N E TNNGGQ ++L+ L+R+D + + D++ +N + A A+ T P G+ + GQ+ +F+++ ++ +GT
Sbjct: 934 DRPAATANTALVRCMAFGPPLHHRLRPPAAGITASTSATIETSQLLGSFFAATAGGATFVFA--LYTDNVRRPSHLALRQATQMQLQHRAPIVALRLIDTKTHCPLLTSSVYLPQFSSPLVPSHHHPLPPHLMVISEEQVRLFSLPSISLRQKARITAKDGFRIKTGNIMAFG--QLSNERNMGIYGIEFNCVFTNNGGQAVVLSVPYLRRRDTIALLGGADVLEINSIVFATAASTRPKVTAAPSLGVYQTAPGQLAIFDMVLAGQRSSALGT 1203
BLAST of Protein lethal(2) giant larvae vs. TrEMBL
Match: A0A5K4F378 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 300.056 bits (767), Expect = 1.207e-80 Identity = 231/854 (27.05%), Postives = 375/854 (43.91%), Query Frame = 1
Query: 106 MTQSIFNSVRKL--NFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRN-----EPQYYSSMKLHSCHEDGSIITWNLPQNS----------DEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANN--------------------------------------EHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDW----------------FQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEI----------WQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADEL-HLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQPF-----------QHIEGSIKTGSNFQVMMSMCIFPPSQITALDILE-------------DNNCNG-----YVIIACGTLHGLVIVSCPK---------ETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRT 2304
M Q IF S R++ +F F+ K + G Y+ D+G +P+ + YD + +L + ++ G I I+G PG+ +S E + + F+ G+ VTLT + + LW +++++ ++ S L + S S + ++NN +D SI++G +G + V+L+ + W +P+ D I+ RI+ + + R+ DAV+ +S RPG LLIGY SG S++++++ D V LL + L A +WC PNR+ +PQ M+L + H DGS+ W+L + L ++ PY C ISK+ W + VF GG+PR+ Y + T++I+ S +D + AN EH+ LDL S L+D + D G V+ L++L EEE ++DL WP + R PYL CLH + +T Y +++V S F + ++ N S WPI+G + + + +DLL+ GH DG++ FW+ GGC+++I T+ ++ LF+ +L H N V + D P R+ G FDP DD+R+AIQ I+ L++GG GQ++++ F V + + F+WKG P + E + + Q + + PP++IT+L + E NN +G +++A GT HG +V PK + L L T+P N A QEA+ GEGWARRRT
Sbjct: 1 MAQKIFQSFRRIPGHFPAFRKKE-EPCDVQGSRYRVAVCSDYGFPSKPTSVAYDPVIDMLAVLTRDGNIYIYGKPGISFSAVHETNAQYIQVVFLTGSRKLVTLTDSDDMYLWELTSVSQTSSQLTQRSCLKRITSQLKSLPSGVPSSSNNNEETSHVTALCYASD-GRSILIGTDNGWVASVRLNTNTATDDFTKF---------WCLPSADDAINPSRILDGISPDRRQRLRADAVVVLSERPGFPGQLLIGYNSGLSLLFDLRSDRVMALLPWQHGLEAAAWC--------GGSGQPNRSNQTPHQPQL--GMRLLTAHSDGSLGVWSLREIGFGTTTISPIQPPLLQMEEAPSMPYGP-FPCKLISKVFWLPSALGGITVFVGGMPRATYGERHTVSILRGSNIDQA-ANASVVAARLAVAAEAEDDDEIPEESSLSAPPIHVFDSDAPEHVCLDLPSSLVDLVPVGSVD-GPVQILVLLCEEEMVVIDLITSGWPFM--RPPYLTCLHTTSLTTYNLITQVSSTLLSNLEAAGAYYGPEGRFGRGGAIADNPSGGGWSSLPWPIQGGHALINGSRLSTSSLGGNILYTDDLLLTGHEDGSVAFWRLSAGGCLRRIYTLYTAILFEDVSQLDHPNGVDDDGDAWPPFRQAGVFDPFMDDSRVAIQFIYLVDNTLVVGGAAGQVIVYQFLNFTPCIEPAIVTIKKSMPGFQWKGHAPLTLRKCFSDKFTANPEQTTPLPAQLQATGVIFVQPPARITSLLLSEFELTHLKEFSQNQTNNISGDGGGLQILLALGTPHGFGVVFVPKPLPNNDSNTKKPLPPQPLLAVSTIPDNIDALQEAAAGEGWARRRT 828 HSP 2 Score: 75.8702 bits (185), Expect = 6.314e-10 Identity = 72/279 (25.81%), Postives = 123/279 (44.09%), Query Frame = 1
Query: 2473 DRPKDTANDGLIRSIRINVSLIKRKGSNGPH--EKLLNLFAGCYGGLLLWFQ--SDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLS-KLNENPDAGFDLDPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLI---CA--------------------------TNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNTRTLC-----PYGICYSGQGQVTLFEII 3192
DR +DTAN +I L K SN + LF G G + + D + N + L ++ QHRAP+L ++ +S + L++ D + L V++EEQ+RL+ P+ LK K R+TA DG+R+K+ S++ F T+ + +KE + C TN GGQ +LL+ L+R D + +D D++A++ + ++ + +N C G+ GQ+TLF+++
Sbjct: 917 DRVQDTANVAIISCFAFGPPLFKSSPSNARPTLHPVATLFIGTKAGTVKLYSIFVDKTTLNSSVLPKLQLYYSRELILQHRAPVLSLRLIDAKSNMPYSLSDYKHYISDSGKSHNLPVLSVVSEEQIRLFNLPNLHLKFKARITAIDGYRIKSASVVGFRIHGKTSSSLSKESTVDSACGDLERSNTSGISVTSQTNQNCEYSFVFTNVGGQAVLLSMPQLRRMDTLHLLDSHDVVAVSSVVFSQPGS-TNVNNSCYVHGPALGLYQLAPGQLTLFDVV 1194
BLAST of Protein lethal(2) giant larvae vs. Ensembl Cavefish
Match: llgl1 (LLGL scribble cell polarity complex component 1 [Source:NCBI gene;Acc:103037820]) HSP 1 Score: 235.728 bits (600), Expect = 1.970e-63 Identity = 247/944 (26.17%), Postives = 435/944 (46.08%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDR----DRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNS--DEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGS----VEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNI-SFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLD---VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + YD KL L+ I +K G IK++G PGV ++ + + + F+ G ++L DN L LW E+ + + S+L V S T IE T ++ L ++ DLL + + G ++P+ + ++D+ D I+ +P + + V + P +LIGY G +++++Q VD L K L +L W R+ + SS H DG + W++ ++ V + P+ C ++KILW+ + L++FSGG+PR+ Y + +TI+ +S +H+ LD TS++IDF T+ D+ S L+VL EEE ++DL WP + PYL LH+S IT +S V + ++++ + + ++ ++ + ++WPI G + + Q +L++ GH DGT+ FW G ++ + + ++++F+ D H + ++ +E P R+ G FDP DD RL IQ L Y+GK L++ G GQ+++ + K + H++D VDL F WKG GS+ FQ ++ + PP+ +TA+ + + N +IA GT HG + + + + A CT+ N + E L R + LKKSLR SFRR+R+ + VS S + + + EV +R IE R D + G++R + + ++ +GP ++AG G + + D ++ + L K+ Q HRAP++ +L + L E + DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L+ FS + +++ ++ L+C TN G
Sbjct: 36 QPSALAYDPKLQLMAIGTKSGAIKVYGSPGVEFTGLHKDTATVTQMHFLHGQGRILSLLDDNTLHLW-------EIGQREQCSSLEEVCSFTIPCR-----------------TVIESTSATRVTVL------LPKLSCDLLAVGTEGG-------GVHFLELPSLT-LLDKSLFQDEIMQSVPDEYKCGKSLGPVESLQEHPQHPDKILIGYSRGLVVLWDLQTRHVDNLFLGKQQLESLVW---------------ERSGNSFVSS------HSDGGYMVWSVSSSTPCTNEPVSSTITYGPF----PCKAVNKILWRTAESGAPLVLFSGGMPRASYGDRHCLTILQDS---------QHVTLDFTSRVIDFFTVHCTDAHSEFDDPSALVVLLEEELVVIDLQTAGWPTI--PAPYLAPLHSSAITCSYHISNVPTKLWERV--VGAGQQQGSLQTHTNWPICGGKNLAPDPK--QQELMLTGHEDGTVRFWD-ASGVSLRPLYKLSTANIFQ-TDCDHNDSLTQAGEEEWPPFRKVGCFDPYSDDPRLGIQKICLCKYSGK-LVVAGTAGQVIVLYLSDEKSD-HMIDVATVDLLQDREGFTWKGHDRLPPKSGSVVFAPGFQPVVLVQCMPPAAVTAVTLHAEWN-----LIAFGTSHGFGLFDYHRRSPVLA-----RCTLHPNDSLAMEGPLS------RVKSLKKSLRQSFRRIRKSRVSGKKRVLVSSPSSKVQEANAHLAEQDAEVTPVQRRIEPRSADDSLSGVVRCLCFADTFLRDGTHHGP-----TMWAGTNSGSVYAYALDVPLQEKFSEQSVEALLGKEIQLMHRAPVVSIAVLDGRG--NPLPEPYEVSRDLAKAPDMQGSHSVLIASEEQFKVFMLPKVSAKTKFKLTAHEGCRVRKVALVNFSS--VASEDYSENGLVCLTNLG 872
BLAST of Protein lethal(2) giant larvae vs. Ensembl Cavefish
Match: llgl1 (LLGL scribble cell polarity complex component 1 [Source:NCBI gene;Acc:103037820]) HSP 1 Score: 234.958 bits (598), Expect = 3.048e-63 Identity = 247/944 (26.17%), Postives = 435/944 (46.08%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDR----DRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSD--EFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGS----VEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNI-SFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLD---VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
+PS + YD KL L+ I +K G IK++G PGV ++ + + + F+ G ++L DN L LW E+ + + S+L V S T IE T ++ L ++ DLL + + G ++P+ + ++D+ D I+ +P + + V + P +LIGY G +++++Q VD L K L +L W R+ + SS H DG + W++ ++ V + P+ C ++KILW+ + L++FSGG+PR+ Y + +TI+ +S +H+ LD TS++IDF T+ D+ S L+VL EEE ++DL WP + PYL LH+S IT +S V + ++++ + + ++ ++ + ++WPI G + + Q +L++ GH DGT+ FW G ++ + + ++++F+ D H + ++ +E P R+ G FDP DD RL IQ L Y+GK L++ G GQ+++ + K + H++D VDL F WKG GS+ FQ ++ + PP+ +TA+ + + N +IA GT HG + + + + A CT+ N + E L R + LKKSLR SFRR+R+ + VS S + + + EV +R IE R D + G++R + + ++ +GP ++AG G + + D ++ + L K+ Q HRAP++ +L + L E + DL P+ + H V++ +EEQ +++ P + K K ++TAH+G R++ +L+ FS + +++ ++ L+C TN G
Sbjct: 10 QPSALAYDPKLQLMAIGTKSGAIKVYGSPGVEFTGLHKDTATVTQMHFLHGQGRILSLLDDNTLHLW-------EIGQREQCSSLEEVCSFTIPCR-----------------TVIESTSATRVTVL------LPKLSCDLLAVGTEGG-------GVHFLELPSLT-LLDKSLFQDEIMQSVPDEYKCGKSLGPVESLQEHPQHPDKILIGYSRGLVVLWDLQTRHVDNLFLGKQQLESLVW---------------ERSGNSFVSS------HSDGGYMVWSVSSSTPCTNEPVSSTITYGPF----PCKAVNKILWRTAESGAPLVLFSGGMPRASYGDRHCLTILQDS---------QHVTLDFTSRVIDFFTVHCTDAHSEFDDPSALVVLLEEELVVIDLQTAGWPTI--PAPYLAPLHSSAITCSYHISNVPTKLWERV--VGAGQQQGSLQTHTNWPICGGKNLAPDPK--QQELMLTGHEDGTVRFWD-ASGVSLRPLYKLSTANIFQ-TDCDHNDSLTQAGEEEWPPFRKVGCFDPYSDDPRLGIQKICLCKYSGK-LVVAGTAGQVIVLYLSDEKSD-HMIDVATVDLLQDREGFTWKGHDRLPPKSGSVVFAPGFQPVVLVQCMPPAAVTAVTLHAEWN-----LIAFGTSHGFGLFDYHRRSPVLA-----RCTLHPNDSLAMEGPLS------RVKSLKKSLRQSFRRIRKSRVSGKKRVLVSSPSSKVQEANAHLAEQDAEVTPVQRRIEPRSADDSLSGVVRCLCFADTFLRDGTHHGP-----TMWAGTNSGSVYAYALDVPLQEKFSEQSVEALLGKEIQLMHRAPVVSIAVLDGRG--NPLPEPYEVSRDLAKAPDMQGSHSVLIASEEQFKVFMLPKVSAKTKFKLTAHEGCRVRKVALVNFSS--VASEDYSENGLVCLTNLG 846
BLAST of Protein lethal(2) giant larvae vs. Ensembl Cavefish
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:103026969]) HSP 1 Score: 197.978 bits (502), Expect = 2.664e-51 Identity = 231/923 (25.03%), Postives = 391/923 (42.36%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDS--GSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRL--------IKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCK 2877
E Y+ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W + +EL ++ + L A S +TA+ + +++G G + V++ + ++ N I + + S++P R ++ V + P + + +LIGY G +++++ + L ++ W ++D + S H DGS W + PQ E + F C ISKIL +Q ++FSGG+PR+ Y + I+++++ H+ LD TS++IDF I D + G L+VL EEE +VDL E WP++ + PYL LH S IT +S + ++++ + + ++ + S WPI G Q + D Q DLL+ GH DGT+ FW G C+ + + ++ +F AD E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + + E+ + VDL F+WKG E + FQ + PP+ +TA+ + + + ++A GT HG + ++ N + CT+ N + E L R K +S R R R + R +P+ + L + N + L E E+ +R IE R D + GL+R++ + + + P +L+AG GG + + +L+ P+ R+ K+ Q HRAP++ +L + L E + DL R PD L+V++EEQ++L+ P + K K
Sbjct: 19 ELYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPRQVELVTLLDDNSLHMWTLRAHKGVSELLEIGRFT-LTGPPGAIPSV---------------TRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENN--------------------ISVEDVQSRVPEEYVGRRNLECVEALQENPLNPRQVLIGYSRGLMVLWDLDRRCAIQHFLGTQQLESVWW------MEDGGNIL---------------SSHSDGSYCHWTVTGKDPQTEPEKQETPYGSFP-------CKAISKILQISTRQGPPFLIFSGGMPRASYGDRHCISVIHSKT---------HVALDFTSRIIDFFVIRDGERHRGDPSALVVLVEEELVVVDLQSEGWPVI--QTPYLVPLHCSAITCSHHVSSIPLKLWERV-QAAGKVQNTHYSKKPWPING-GQNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLYPMYKLSTAMVFHTDADPNDNMNQGTEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQILVLEINDEEAEQTVEATVVDLLQGQEGFRWKGQARLDLREEPVTFPPGFQPFALVQCQPPAVVTAIALHSE-----WKLVAFGTSHGFGVYDYQQKNN-----VMVKCTLNPNDQVALEGPLS-----RVKSIKKSLRQSFRRIRRSRVSMRKHNPTNAAKLHEINARLEAEALQEMELAPVQRKIEARSADDSFTGLVRTLYFADTFLSDSSQSTP-----SLWAGTNGGAVYAY--------MLRLPPVERRMDDQLTAYAAKEIQLMHRAPVVGLVVLDGRG--APLPEPLEVAHDL--ARSPDMQGSHQLLVISEEQLKLFNLPKVSSKAK 829
BLAST of Protein lethal(2) giant larvae vs. Ensembl Cavefish
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:103026969]) HSP 1 Score: 197.593 bits (501), Expect = 3.365e-51 Identity = 231/923 (25.03%), Postives = 391/923 (42.36%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTL--TNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNL----PQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDY-LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDS--GSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRL--------IKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCK 2877
E Y+ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W + +EL ++ + L A S +TA+ + +++G G + V++ + ++ N I + + S++P R ++ V + P + + +LIGY G +++++ + L ++ W ++D + S H DGS W + PQ E + F C ISKIL +Q ++FSGG+PR+ Y + I+++++ H+ LD TS++IDF I D + G L+VL EEE +VDL E WP++ + PYL LH S IT +S + ++++ + + ++ + S WPI G Q + D Q DLL+ GH DGT+ FW G C+ + + ++ +F AD E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + + E+ + VDL F+WKG E + FQ + PP+ +TA+ + + + ++A GT HG + ++ N + CT+ N + E L R K +S R R R + R +P+ + L + N + L E E+ +R IE R D + GL+R++ + + + P +L+AG GG + + +L+ P+ R+ K+ Q HRAP++ +L + L E + DL R PD L+V++EEQ++L+ P + K K
Sbjct: 19 ELYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPRQVELVTLLDDNSLHMWTLRAHKGVSELLEIGRFT-LTGPPGAIPSV---------------TRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENN--------------------ISVEDVQSRVPEEYVGRRNLECVEALQENPLNPRQVLIGYSRGLMVLWDLDRRCAIQHFLGTQQLESVWW------MEDGGNIL---------------SSHSDGSYCHWTVTGKDPQTEPEKQETPYGSFP-------CKAISKILQISTRQGPPFLIFSGGMPRASYGDRHCISVIHSKT---------HVALDFTSRIIDFFVIRDGERHRGDPSALVVLVEEELVVVDLQSEGWPVI--QTPYLVPLHCSAITCSHHVSSIPLKLWERV-QAAGKVQNTHYSKKPWPING-GQNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLYPMYKLSTAMVFHTDADPNDNMNQGTEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQILVLEINDEEAEQTVEATVVDLLQGQEGFRWKGQARLDLREEPVTFPPGFQPFALVQCQPPAVVTAIALHSE-----WKLVAFGTSHGFGVYDYQQKNN-----VMVKCTLNPNDQVALEGPLS-----RVKSIKKSLRQSFRRIRRSRVSMRKHNPTNAAKLHEINARLEAEALQEMELAPVQRKIEARSADDSFTGLVRTLYFADTFLSDSSQSTP-----SLWAGTNGGAVYAY--------MLRLPPVERRMDDQLTAYAAKEIQLMHRAPVVGLVVLDGRG--APLPEPLEVAHDL--ARSPDMQGSHQLLVISEEQLKLFNLPKVSSKAK 829
BLAST of Protein lethal(2) giant larvae vs. Ensembl Cavefish
Match: stxbp5l (syntaxin binding protein 5-like [Source:NCBI gene;Acc:567605]) HSP 1 Score: 114.775 bits (286), Expect = 2.420e-25 Identity = 84/390 (21.54%), Postives = 170/390 (43.59%), Query Frame = 1
Query: 811 VIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQK------CLPISKILWKRYK-QDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDD----NDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYT--GKHLLIGGYGGQIVLWGFQEN 1941
V+H+S P LLIG+ SG ++++++ DF + ++++SW ++ + H DGS+ WNL + FQ+ P+ K Q+ C PI K+ +K + + ++FSGGL + T+TIM+ + VL++ +++F + + N+ ++VL E++F +VDLT+ ++PI + P +H SP+T + ++ D L + + + S +WP+ G V + +++I GH DG+I FW ++ + +K+S +F+ TG+ +++ A+Q++ + + + G ++L+ F ++
Sbjct: 204 VVHLSDSPKDEGKLLIGFESGTIVMWDLRAKRTDFRIYYDEAIHSVSW---------------------HHEGRQFMCSHSDGSLSMWNLRNTAKP-----FQVTFPHGKSQRDGRKESCKPILKVEYKTCRNSEPFVIFSGGLSYDKAGRRPTLTIMHGKAIT---------VLEMDHPIVEFIVLCETPYLNEVQEPYAVVVLLEKDFIVVDLTQSNFPIFENAYPMD--IHESPVTCTAYFADCPPDIIPVLYSIGAKHKKTGYSHKEWPVSGGTWTVGSQTY--PEIIITGHADGSIKFWD-ATAITLQMLYKLKTSKVFEKPKGAE---------------TGRSAELVEEDPYAVQMVSWCPQSRIFCVVGISAHVILYRFSKH 538
BLAST of Protein lethal(2) giant larvae vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003125.1 (pep scaffold:Pmarinus_7.0:GL479844:12808:29279:-1 gene:ENSPMAG00000002854.1 transcript:ENSPMAT00000003125.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.961 bits (341), Expect = 7.750e-33 Identity = 163/634 (25.71%), Postives = 275/634 (43.38%), Query Frame = 1
Query: 1198 LIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEE-------FFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKE----DCNISFSDWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVL---WGFQENKYEKHLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHP-SVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDR---PK--DTANDGLIRSIRINVSLIKRKGS---NGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
L+VF GG+PR+ + + +T+ + H D TS+++DF T+ + + ++DL + WP + PYL+ LH+S IT ++ V +++++ + S S WPI G RN E + +LL+ GH DGT+ FW G + + + ++ LF+ E DDE P + G FDP DD RL IQ L ++G+ LL+ G GQ+VL G + E ++ VDL F WKG + G + ++ + + + PP+ +TAL + + + ++A GT HG + K A V+ CT+ P TLA E L +R ++ + R R S K+ P S + + + N + + E + A R P+ D + GL+R + + + R G+ +GP L+ G G + + D + I+ L K+ Q HRAP++ +L L E +A DL + H L++ +EEQ ++++ P T K K ++TAH+G R++ +L + R + + + L+C TN G
Sbjct: 1 LLVFGGGMPRASFGDRHCVTV--------RRGGGRHAAFDFTSRVVDFFTVHGDATAGGAGSGGDATALVVLVEEELVVLDLATDGWPTVP--PPYLSPLHSSAITCSCHVAAVPLRLWERVSATGRAQRALAPSAVSSASSWPILGG----RNLLPEPSERNLLLTGHEDGTVRFWD-ASGAGLTPLYILSTAPLFQTDGEHSEGLGPASDDEWPPFVKVGCFDPYSDDPRLGIQKISLCKFSGR-LLVAGTAGQVVLIMELGDEAAVQEIAVVTVDLLKEREGFAWKGHERLVVRPGPRTLPAGYRPGLLLQVLPPAAVTALVLHAE-----WRLLAFGTSHGFGLFDYQK-----AHVVFARCTLHPSETLA-LEGPL----SRVKSLKKSLRQSFRRIRKSRVSGKKRADPGSPATKVQEANARLAEQQQEEAAARDADVAPVQRRVEPRSLDDSLSGLVRCLYFADTFL-RDGTLAHSGP-----TLWVGTNAGTVFAYSLDVPSPDRRSELAIHALLAKEIQLMHRAPVVSVWVLDGRG--RPLPEPLEASHDLARAAEMQGGHSLLIASEEQFKVFSLPKVTAKTKFKLTAHEGARVRKVALCDAAGQR--DEWHGRSLLLCLTNLG 593
BLAST of Protein lethal(2) giant larvae vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003126.1 (pep scaffold:Pmarinus_7.0:GL479844:18893:28646:-1 gene:ENSPMAG00000002854.1 transcript:ENSPMAT00000003126.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 121.709 bits (304), Expect = 7.204e-29 Identity = 147/589 (24.96%), Postives = 245/589 (41.60%), Query Frame = 1
Query: 1459 PYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRN--DEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE-IPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVL---WGFQENKYEKHLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLA---------SQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDR---PK--DTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDL--DPNRKPDH-LVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNTRTLCPY 3144
PYL+ LH+S IT ++ V +++++ + S S WPI G RN E + +LL+ GH DGT+ FW G + + + ++ LF+ E DDE P + G FDP DD RL IQ L ++G+ LL+ G GQ+VL G + E ++ VDL F WKG + G + ++ + + + PP+ +TAL + + + ++A GT HG + K A V+ CT+ P TLA S + SL + + R R + R V + + N + + E + A R P+ D + GL+R + + ++ P L+ G G + + D + I+ L K+ Q HRAP++ +L L E +A DL + H L++ +EEQ ++++ P T K K ++TAH+G R++ +L + R + + + L+C TN G ++ L+ V K D+ A++ A R P+
Sbjct: 6 PYLSPLHSSAITCSCHVAAVPLRLWERVSATGRAQRALAPSAS-WPILGG----RNLLPEPSERNLLLTGHEDGTVRFWD-ASGAGLTPLYILSTAPLFQTDGEHSEGLGPASDDEWPPFVKVGCFDPYSDDPRLGIQKISLCKFSGR-LLVAGTAGQVVLIMELGDEAAVQEIAVVTVDLLKEREGFAWKGHERLVVRPGPRTLPAGYRPGLLLQVLPPAAVTALVLHAE-----WRLLAFGTSHGFGLFDYQK-----AHVVFARCTLHPSETLALEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRDPPPPP-----------PVGAQVQEANARLAEQQQEEAAARDADVAPVQRRVEPRSLDDSLSGLVRCLYFADTFLRDGTRQCP-----TLWVGTNAGTVFAYSLDVPSPDRRSELAIHALLAKEIQLMHRAPVVSVWVLDGRG--RPLPEPLEASHDLARAAEMQGGHSLLIASEEQFKVFSLPKVTAKTKFKLTAHEGARVRKVALCDAAGQR--DEWHGRSLLLCLTNL-GDVHTVSVPGLRPLSRHACVRKEDISAVSSCLFTATAQGVGVRCPSPW 556
BLAST of Protein lethal(2) giant larvae vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003932.1 (pep scaffold:Pmarinus_7.0:GL482330:1953:13145:-1 gene:ENSPMAG00000003602.1 transcript:ENSPMAT00000003932.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 50.8322 bits (120), Expect = 4.251e-8 Identity = 32/89 (35.96%), Postives = 46/89 (51.69%), Query Frame = 1
Query: 208 QSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLI------STLT 456
Q++E G +PS + YD L L+ I +K G +KI+G PGV ++ + + F+PG V+L D L LW I STLT
Sbjct: 1 QTVEH-GFPHQPSALAYDPDLRLMAIGTKSGAVKIYGAPGVEFTGLHRDIAIVTQLHFLPGQARVVSLLDDGSLHLWEIVEKDGYSTLT 88
BLAST of Protein lethal(2) giant larvae vs. Ensembl Nematostella
Match: EDO48036 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKR7]) HSP 1 Score: 211.846 bits (538), Expect = 1.646e-56 Identity = 218/904 (24.12%), Postives = 381/904 (42.15%), Query Frame = 1
Query: 238 EPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTAD---NKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDS----GSVEYLLVLTEEEFFIVDL-TKE-SWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDE--IPLRRTGQFDPCCDDNRLAIQ--LIHYTGKHLLIGGYGGQIVLWGF--QENKYEKHLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPK-DTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDG 2901
+PS + D KL+LL I ++ G ++IFG PGV + + Q I + F+P +++ D N + LW E+ K D S L V + ++ + T+ +++G G++ + ++ ++++ VI +D ++ + S+ +V I P +LIGY+ G ++++N + SV L +LSW ++ K S H DGS+ + + +S E F P+ C I+KI W D + F+GG+PR+ Y K+ I+++ S +V D TS++IDF T+ + L VL E+E ++DL TKE +P +PYL CLH+SPIT S + ++ ++ S WPI G V + E D+LI GH DG++ FW M+ + T+ +S +F E H N ++E P ++ G FDP DD R A+Q L+ L I G GGQI+++ QE E + ++DL +WKG P EG++ T FQ + + P + I++L + C + +A GT HG ++ +TN + V+TT CTV L ++ GE +R+++ + R R+ T++ + P R + T + + + D ++R I + +K +G H G + +++ + EN K+ + + K+ + +H+API+ ++ + + D G D+ LV+ +EEQ ++++ P + K ++TA DG
Sbjct: 39 KPSALAQDPKLNLLAIGTEDGTLRIFGRPGVQLTACHDNQTRIQELHFLPEQGRVISVCDDGEQNSIHLW-------EVNKKDGKSVLEEVKTCTLEGRCEARICICCLSMK------------TNRLLLGTEGGNIYLLDINSFELQEY---------------------VIYQDVVMQSVQEDSKTNA--GSVEAIQEHPNDSNKILIGYKKGLTVLWNHESCSVQQTFPNSIDLESLSW---------------------HHGGDKFISAHADGSLTEYTIVSDS-ETTGETSTPFGPFP----CKAITKIEW----HDNSVFFAGGMPRASYGDKNCISLVQGS--------TTQVVFDFTSRVIDFITVIPLTTVGFLAEPACLAVLCEQELVVIDLKTKEQGYPTF--MKPYLTCLHSSPITTSYHCHGCPSQLWNQICAAGKDQIQSEYSHESWPITGGKTLVEDAET--KDILITGHEDGSVQFWDVSQVE-MQLMYTLSTSKMFISDHEGHDNGTQEVEEEGWPPFKKVGNFDPFSDDPRFAVQKILLSTENNMLTIAGNGGQILVYEINDQEKDIELQVTEIDLVEDKEKLQWKGHGPLAVKEGAVCTPRGFQPVQGVQFIPAAAISSLAV-----CPKWGALAAGTCHGFALL----DTNTKK-VVTTKCTVSSEEL----SATGEPISRKKSLKKSIRDSFRRLRRSRKGTRKGDTP---RKEGEAGAATPPQSPAAAPQSPPVQRLVHESRVDETVLSMVRCIYFVETFVK----DGVHHSPSMWVGTNAGHIYVYYITLPDEEN--KDHGLEAEVGKEIKLKHKAPIVAIFVVDKDGSPILADSENDKGVDMSGQHS---LVICSEEQFKVFSLPHLKARQKEKLTAIDG 831
BLAST of Protein lethal(2) giant larvae vs. Ensembl Nematostella
Match: EDO30312 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T154]) HSP 1 Score: 57.3806 bits (137), Expect = 3.177e-8 Identity = 32/109 (29.36%), Postives = 51/109 (46.79%), Query Frame = 1
Query: 1381 LLVLTEEEFFIVDLTK--ESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKE----DCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFW 1689
++ +T + D+ S P+ D PY +H SP+T Q+++E D + L E+ + S WPI G A R + ++L+I GH DGT+ FW
Sbjct: 155 IIAITPARLLVFDVASALSSKPVTFD-VPYAFEIHESPVTCTQYITECPPDLIRALREVGGRPKKKLLQREASRQPWPITGGAINDRETDDESSELIITGHADGTVRFW 262
BLAST of Protein lethal(2) giant larvae vs. Ensembl Medaka
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:101172480]) HSP 1 Score: 219.935 bits (559), Expect = 2.112e-58 Identity = 244/951 (25.66%), Postives = 412/951 (43.32%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKIL-WKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDD--NDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
E ++ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W TL +++ V + A ITA+ + +++G G + V++ + ++ N I +++ S++P R ++ V + P ++IGY G ++++++K S+ + L ++ W +D + S H DGS W + + D +PY C ISKI+ + ++FSGG+PR+ Y + IT+++ H+ LD TS++IDF I + + G L+VL EEE ++DL E WP++ + PYL LH+S IT +S + +++++ + + + S WPI+G Q + D Q DLL+ GH DGT+ FW G C+ + + ++++F AD S E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + E+ + VDL F+WKG E ++ FQ + PP+ +TAL + + + ++A GT HG + ++ N + CT+ P + LA EG R K +S R R R + R H + S L + N + + EL E E+ +R IE R D + GL+R + + + N P +L+AG GG + + I + K+ Q HRAP++ +L + L E + DL R PD HL+V++EEQ +++ P + K K+++TA DG R++ + F +R T++ + L+ TN G
Sbjct: 39 ELFQFSKTVEHGFPHQPSALGHSSSLQLLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPHQVELVTLLDDNSLHMW---TLKGHKGVSELLEIGRFVLTGPPGA-----------LPSVTRITAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEERN--------------------ISLEQVTSRVPDNYIGRRNLEHVEALQENPADANQVVIGYGRGVLVVWDLKKHSLLQCICPSQALESVWW------TEDGGCIL---------------SSHTDGSYCRWTVGETDGNEEKSD----TPYGTF-PCKAISKIMQLPTAEGPPFLLFSGGMPRASYGDRHCITVIHG---------KSHVALDFTSRIIDFFVIREGPHHKGDPSALVVLVEEELVVIDLQAEGWPVV--QTPYLVPLHSSAITCSHHVSAIPLKLWERISAAGA-LQSTHYSKKLWPIRG-GQNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLSPVYKLSTAAVFHTDADPNDNMNHSTEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQIMVLELNDEAAEQTVEAQVVDLLQGQEGFRWKGHTQLDVREDPVQFPPGFQPFTLVQCQPPAVVTALILHSE-----WKLVAFGTSHGFGLFDYQQKKN-----VLVKCTLNPSDQLAM------EGPLSRVKSIKKSLRQSFRRIRRSRVSLRKHHVNSSAKLQEANAR-LEAELAEMELAPVQRKIEARSSDDSFTGLVRVLYFADTFLTDSTHNTP-----SLWAGTNGGCVFAYILHLPTMEHRGEELITAQPAKEIQLMHRAPVVGVVVLDGHG--TPLPEPLEVAHDL--ARSPDMHGSHHLLVVSEEQFKVFTLPKVSAKTKLKLTAIDGSRVRKVGVAWFGSNR--TEDYGESGLLVLTNQG 885
BLAST of Protein lethal(2) giant larvae vs. Ensembl Medaka
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:101172480]) HSP 1 Score: 219.164 bits (557), Expect = 3.748e-58 Identity = 244/951 (25.66%), Postives = 412/951 (43.32%), Query Frame = 1
Query: 193 EFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKIL-WKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDD--NDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
E ++ + G +PS + + L LL I ++ G IK++G PGV + + + + F+P VTL DN L +W TL +++ V + A ITA+ + +++G G + V++ + ++ N I +++ S++P R ++ V + P ++IGY G ++++++K S+ + L ++ W +D + S H DGS W + + D +PY C ISKI+ + ++FSGG+PR+ Y + IT+++ H+ LD TS++IDF I + + G L+VL EEE ++DL E WP++ + PYL LH+S IT +S + +++++ + + + S WPI+G Q + D Q DLL+ GH DGT+ FW G C+ + + ++++F AD S E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + E+ + VDL F+WKG E ++ FQ + PP+ +TAL + + + ++A GT HG + ++ N + CT+ P + LA EG R K +S R R R + R H + S L + N + + EL E E+ +R IE R D + GL+R + + + N P +L+AG GG + + I + K+ Q HRAP++ +L + L E + DL R PD HL+V++EEQ +++ P + K K+++TA DG R++ + F +R T++ + L+ TN G
Sbjct: 39 ELFQFSKTVEHGFPHQPSALGHSSSLQLLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPHQVELVTLLDDNSLHMW---TLKGHKGVSELLEIGRFVLTGPPGA-----------LPSVTRITAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEERN--------------------ISLEQVTSRVPDNYIGRRNLEHVEALQENPADANQVVIGYGRGVLVVWDLKKHSLLQCICPSQALESVWW------TEDGGCIL---------------SSHTDGSYCRWTVGETDGNEEKSD----TPYGTF-PCKAISKIMQLPTAEGPPFLLFSGGMPRASYGDRHCITVIHG---------KSHVALDFTSRIIDFFVIREGPHHKGDPSALVVLVEEELVVIDLQAEGWPVV--QTPYLVPLHSSAITCSHHVSAIPLKLWERISAAGA-LQSTHYSKKLWPIRG-GQNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLSPVYKLSTAAVFHTDADPNDNMNHSTEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQIMVLELNDEAAEQTVEAQVVDLLQGQEGFRWKGHTQLDVREDPVQFPPGFQPFTLVQCQPPAVVTALILHSE-----WKLVAFGTSHGFGLFDYQQKKN-----VLVKCTLNPSDQLAM------EGPLSRVKSIKKSLRQSFRRIRRSRVSLRKHHVNSSAKLQEANAR-LEAELAEMELAPVQRKIEARSSDDSFTGLVRVLYFADTFLTDSTHNTP-----SLWAGTNGGCVFAYILHLPTMEHRGEELITAQPAKEIQLMHRAPVVGVVVLDGHG--TPLPEPLEVAHDL--ARSPDMHGSHHLLVVSEEQFKVFTLPKVSAKTKLKLTAIDGSRVRKVGVAWFGSNR--TEDYGESGLLVLTNQG 885
BLAST of Protein lethal(2) giant larvae vs. Ensembl Medaka
Match: LLGL1 (LLGL scribble cell polarity complex component 1 [Source:NCBI gene;Acc:101167542]) HSP 1 Score: 213.386 bits (542), Expect = 2.549e-56 Identity = 257/1034 (24.85%), Postives = 443/1034 (42.84%), Query Frame = 1
Query: 148 YNFKTKYIN-QNESIGE--FYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILW-LISTLTNEL--FKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFS---PYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDV---DLTTHLSNFKWKGCQPFQHIEGSIKTG---SNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWF-------------------QSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENP-DAGFDLD--PNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNAN 3114
+ F+ + + Q E I + F K+++E G +PS + +D KL L+ I +K G IKI+G PGV ++ + + I F+PG +++ DN + W L++ T E+ K + + +L V+S + ++ T + + + MG G + ++L L +++ T+ Q D + LP + + V + P +LIGY G +++++ D L K L +L W R+ + SS H DG W + + + + Q S PY C I+KILW R +I++SGG+PR+ Y + +TI + + EH+ LD TS++IDF T+ +D + L+VL EEE ++DL WP L PYL LH+S IT ++ V + +++L ++ + WPI G K Q +LL+ GH DGT+ FW G + + + ++++F + E E++ P R+ G FDP DD RL IQ L Y+ K L++ G GQ+++ G + + + HL+DV DL F WKG +E +K FQ ++ + PP+ +TA+ + + N ++A GT HG + + + A CT+ N + E L +R ++ + R R S K+ + + + + N + EV +R IE R D + G++R + ++ +GP L+AG G + + +S VE +L K+ Q HRAP++ +L G K +P +A DL P+ H V++ +EEQ+++++ P + K K ++TAH+G R++ +L++FS + ++ L+C TN G L N L+ + + K D+ + KN
Sbjct: 4 FRFRRQSTDPQREKIKQELFAFKKTVE-HGFPHQPSALAFDPKLQLMAIGTKSGAIKIYGAPGVEFTGLHKDTTAVTQILFLPGRGCLLSVLDDNTIHRWELVAESTREVGGVKKEGVVSLREVDSYSLPGRPGIESSSATRV------TVLLLLKSCDLLCMGTEGGGVYVLELPRLSLKEN----------QTLLQ----------DHVTQSLPDDYRCGKSLGPVESLQEHPQQAGKILIGYSRGLVVLWDLSSRHADQLFLGKQQLESLVW---------------ERSGNLFVSS------HNDGGYSVWAVTNGN----IYNHQPVSSTIPYGP-FPCKAITKILW-RTTHSPVILYSGGMPRASYGDRHCLTI---------QQDKEHVTLDFTSRVIDFFTVHNMDNDKEFDDPSALVVLLEEELVVIDLLTPGWPSL--PTPYLAPLHSSAITCSCHVTNVSTKLWERLINAGKAQQSRRHTHRKWPICG--GKNLAPPPRQQELLLTGHEDGTVRFWD-ASGVALTPLYKLSTANVFHTDEMQQQQEEEEEEEWPPFRKVGCFDPYSDDPRLGIQKISLCKYSNK-LVVAGTAGQVIVLGLNDERSD-HLVDVSVMDLLQDREGFTWKG---HDRLEPRLKPAPFLPGFQPLVLLQCLPPASVTAVALHTEWN-----LVAFGTSHGFGLFDYHRRNAVLA-----RCTLHPNDSLAMEGPL----SRVKSLKKSLRQSFRRIRKSRVSGKKRAVITTTSKVQEANAALAE----QEEVAPVQRRIEPRSADDSLSGVVRCFCFADTFLRDGTHHGP-----TLWAGTNSGSVYAYALEVPGVDSGRTCERGGASESSMCVEAVLG---------KEIQLMHRAPVVSICVL---DGRGKPLPDPYEASQDLSIAPDMTNAHSVLIASEEQLKVFSLPKVSAKTKFKLTAHEGCRVRKVALVLFSS--AVQEEYSEHTLVCLTNM-GDMHLFNMPGLRPQVRFDCIRKEDISGIASCVFTKNGQ 926
BLAST of Protein lethal(2) giant larvae vs. Ensembl Medaka
Match: llgl2 (LLGL scribble cell polarity complex component 2 [Source:NCBI gene;Acc:101172480]) HSP 1 Score: 189.504 bits (480), Expect = 1.240e-48 Identity = 211/777 (27.16%), Postives = 351/777 (45.17%), Query Frame = 1
Query: 745 IDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMK----------LHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKIL-WKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDD--NDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKM-ADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIH---YTGKHLLIGGYGGQIVLWGFQENKYEKHLLD--VDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTV-PRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPD-----HLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNG 3000
I +++ S++P R ++ V + P ++IGY G ++++++K S+ + S + FM + N Y+ +++ + S H DGS W + + D +PY C ISKI+ + ++FSGG+PR+ Y + IT+++ H+ LD TS++IDF I + + G L+VL EEE ++DL E WP++ + PYL LH+S IT +S + +++++ + + + S WPI+G Q + D Q DLL+ GH DGT+ FW G C+ + + ++++F AD S E + P R+ G FDP DD RL IQ IH Y+G +L + G GQI++ + E+ + VDL F+WKG E ++ FQ + PP+ +TAL + + + ++A GT HG + ++ N + CT+ P + LA EG R K +S R R R + R H + S L + N + + EL E E+ +R IE R D + GL+R + + + N P +L+AG GG + + I + K+ Q HRAP++ +L + L E + DL R PD HL+V++EEQ +++ P + K K+++TA DG R++ + F +R T++ + L+ TN G
Sbjct: 189 ISLEQVTSRVPDNYIGRRNLEHVEALQENPADANQVVIGYGRGVLVVWDLKKHSLLQCICPSQVRCPSSMGMILRMQLKGFMQS-NEAPLLYFQALESVWWTEDGGCILSSHTDGSYCRWTVGETDGNEEKSD----TPYGTF-PCKAISKIMQLPTAEGPPFLLFSGGMPRASYGDRHCITVIHG---------KSHVALDFTSRIIDFFVIREGPHHKGDPSALVVLVEEELVVIDLQAEGWPVV--QTPYLVPLHSSAITCSHHVSAIPLKLWERISAAGA-LQSTHYSKKLWPIRG-GQNLAPDPP-QRDLLLTGHEDGTVRFWD-ASGVCLSPVYKLSTAAVFHTDADPNDNMNHSTEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSG-YLTVAGTAGQIMVLELNDEAAEQTVEAQVVDLLQGQEGFRWKGHTQLDVREDPVQFPPGFQPFTLVQCQPPAVVTALILHSE-----WKLVAFGTSHGFGLFDYQQKKN-----VLVKCTLNPSDQLAM------EGPLSRVKSIKKSLRQSFRRIRRSRVSLRKHHVNSSAKLQEANAR-LEAELAEMELAPVQRKIEARSSDDSFTGLVRVLYFADTFLTDSTHNTP-----SLWAGTNGGCVFAYILHLPTMEHRGEELITAQPAKEIQLMHRAPVVGVVVLDGHG--TPLPEPLEVAHDL--ARSPDMHGSHHLLVVSEEQFKVFTLPKVSAKTKLKLTAIDGSRVRKVGVAWFGSNR--TEDYGESGLLVLTNQG 915
BLAST of Protein lethal(2) giant larvae vs. Ensembl Medaka
Match: LLGL1 (LLGL scribble cell polarity complex component 1 [Source:NCBI gene;Acc:101167542]) HSP 1 Score: 174.096 bits (440), Expect = 9.473e-44 Identity = 183/713 (25.67%), Postives = 309/713 (43.34%), Query Frame = 1
Query: 148 YNFKTKYIN-QNESIGE--FYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILW-LISTLTNEL--FKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFS---PYKKDQKCLPISKILWKRYK-QDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTI----DDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDEI--------------PLRRTGQFDPCCDDNRLAIQ---LIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDV---DLTTHLSNFKWKGCQPFQHIEGSIKTG---SNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGL 2175
+ F+ + + Q E I + F K+++E G +PS + +D KL L+ I +K G IKI+G PGV ++ + + I F+PG +++ DN + W L++ T E+ K + + +L V+S + ++ T + + + MG G + ++L L +++ T+ Q D + LP + + V + P +LIGY G +++++ D L K L +L W R+ + SS H DG W + + + + Q S PY C I+KILW+ + +I++SGG+PR+ Y + +TI + + EH+ LD TS++IDF T+ +D + L+VL EEE ++DL WP L PYL LH+S IT ++ V + +++L ++ + WPI G K Q +LL+ GH DGT+ FW G + + + ++++F + + DD P R+ G FDP DD RL IQ L Y+ K L++ G GQ+++ G + + + HL+DV DL F WKG +E +K FQ ++ + PP+ +TA+ + + N ++A GT HG
Sbjct: 4 FRFRRQSTDPQREKIKQELFAFKKTVE-HGFPHQPSALAFDPKLQLMAIGTKSGAIKIYGAPGVEFTGLHKDTTAVTQILFLPGRGCLLSVLDDNTIHRWELVAESTREVGGVKKEGVVSLREVDSYSLPGRPGIESSSATRV------TVLLLLKSCDLLCMGTEGGGVYVLELPRLSLKEN----------QTLLQ----------DHVTQSLPDDYRCGKSLGPVESLQEHPQQAGKILIGYSRGLVVLWDLSSRHADQLFLGKQQLESLVW---------------ERSGNLFVSS------HNDGGYSVWAVTNGN----IYNHQPVSSTIPYGP-FPCKAITKILWRTTQLSSPVILYSGGMPRASYGDRHCLTI---------QQDKEHVTLDFTSRVIDFFTVHNMDNDKEFDDPSALVVLLEEELVVIDLLTPGWPSL--PTPYLAPLHSSAITCSCHVTNVSTKLWERLINAGKAQQSRRHTHRKWPICG--GKNLAPPPRQQELLLTGHEDGTVRFWD-ASGVALTPLYKLSTANVFHTDGDPIDDPHDPCDDPEMQQQQEEEEEEEWPPFRKVGCFDPYSDDPRLGIQKISLCKYSNK-LVVAGTAGQVIVLGLNDERSD-HLVDVSVMDLLQDREGFTWKG---HDRLEPRLKPAPFLPGFQPLVLLQCLPPASVTAVALHTEWN-----LVAFGTSHGF 639 HSP 2 Score: 59.3066 bits (142), Expect = 2.560e-8 Identity = 43/151 (28.48%), Postives = 76/151 (50.33%), Query Frame = 1
Query: 2674 LIKQYQFQHRAPILHFNMLSPESGLSKLNENP-DAGFDLD--PNRKPDHLVVL-TEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNAN 3114
L K+ Q HRAP++ +L G K +P +A DL P+ H V++ +EEQ+++++ P + K K ++TAH+G R++ +L++FS + ++ L+C TN G L N L+ + + K D+ + KN
Sbjct: 798 LGKEIQLMHRAPVVSICVLD---GRGKPLPDPYEASQDLSIAPDMTNAHSVLIASEEQLKVFSLPKVSAKTKFKLTAHEGCRVRKVALVLFSS--AVQEEYSEHTLVCLTNM-GDMHLFNMPGLRPQVRFDCIRKEDISGIASCVFTKNGQ 942
BLAST of Protein lethal(2) giant larvae vs. Planmine SMEST
Match: SMESG000072512.1 (SMESG000072512.1) HSP 1 Score: 2023.05 bits (5240), Expect = 0.000e+0 Identity = 1038/1044 (99.43%), Postives = 1040/1044 (99.62%), Query Frame = 1
Query: 106 MTQSIFNSVRKLNFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHXXXXXXXXXXXXXXXXXTAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLPISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEYLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTXXXXXXXXXXXXXXXXXXXXXMEHPSVSRHLSDNNDKTMRXXXXXXXXXXXXXXXXDRPKDTANDGLIRSIRINVSLIKRKGSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDAGFDLDPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKEPLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNTRTLCPYGICYSGQGQVTLFEIISKTKTIGTHSSGYFW 3237
MTQSIFNSVRKLNFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHNQSDYNNNNENSIEQNITAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCL ISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVE+LLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTRELKKSLRSSFRRLRRRSTKRMEHPSVSRHLSDNNDKTMRVELVENEVEFEERAIEDRPKDTANDGLIRSIRINVSLIKRK SNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDA FDLDPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTK+PLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSN RTLCPYGICYSGQGQVTLFEIISKTKTIGTHSSGYFW
Sbjct: 1 MTQSIFNSVRKLNFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILWLISTLTNELFKVDVISNLNVVNSARTSAHNQSDYNNNNENSIEQNITAIEVNDLTSSIIMGNGSGSLIQVKLDLLKMRKQANNYKTVPPGNTIWQMPTKSDVIDRDRIISKLPIGSQNRVIIDAVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKCLLISKILWKRYKQDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEFLLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSSNKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWKFGMGGCMKKISTVKSSSLFKMADELHLNEVSYEDDEIPLRRTGQFDPCCDDNRLAIQLIHYTGKHLLIGGYGGQIVLWGFQENKYEKHLLDVDLTTHLSNFKWKGCQPFQHIEGSIKTGSNFQVMMSMCIFPPSQITALDILEDNNCNGYVIIACGTLHGLVIVSCPKETNLEALVLTTHCTVPRNTLASQEASLGEGWARRRTRELKKSLRSSFRRLRRRSTKRMEHPSVSRHLSDNNDKTMRVELVENEVEFEERAIEDRPKDTANDGLIRSIRINVSLIKRKCSNGPHEKLLNLFAGCYGGLLLWFQSDYSVENILKNSPINLRLIKQYQFQHRAPILHFNMLSPESGLSKLNENPDADFDLDPNRKPDHLVVLTEEQVRLYAFPSFTLKCKIRVTAHDGFRLKNGSLIVFSDDRLTTQNNTKQPLICATNNGGQFLLLNCVNLKRKDVVQFVDKTDLMALNFMSLAKNANLSNARTLCPYGICYSGQGQVTLFEIISKTKTIGTHSSGYFW 1044
BLAST of Protein lethal(2) giant larvae vs. Planmine SMEST
Match: SMESG000025197.1 (SMESG000025197.1) HSP 1 Score: 86.6557 bits (213), Expect = 6.118e-17 Identity = 74/309 (23.95%), Postives = 134/309 (43.37%), Query Frame = 1
Query: 808 AVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKC--LPISKILWKRYK-QDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEY----LLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSS-------NKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWK 1692
+++ ++ P LLIG+ +G ++N+++ S F L L W P NF+ +CH G ++TWN N V+ Q + DQK PI KI+ K ++ ++VFSGG P+ + + ++ + + +L + +IDF + D+ S + + +L + + ++DL ++P + PY LH SP+T ++S+ D+ L S NK ++S +WPI G + ++++I GH DG+I FW+
Sbjct: 191 SIVQMADNPADSNKLLIGFSTGFLSLWNLREKSAKFRFKYAEVLCGLCWYPDG----KNFI-----------------TCHHGGYLVTWNSRVNQGPLTVI--QPHNRDNMDQKIGFEPIRKIVLLTTKSEESIMVFSGGTPKVPNPNSDSTEVSSSFPSVTVMKDKRLTILQMDYPVIDFAQLCDSCSQNCFTDPIGIAILLQNDLMVIDLLSPNYPSFEN--PYPIDLHVSPVTCLHYISDCPGDFVASLYTAKSRIKRPVQNKSQGSMSVHEWPINGGQWGSLLNP--HSEMIITGHADGSIRFWE 472 HSP 2 Score: 51.6026 bits (122), Expect = 3.709e-6 Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 1
Query: 100 SKMTQSIFNSVRKLNFYNFKTKYINQNESI--GEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILW 438
SK Q + + +R N + + N+ E + +K +I +G EP+CI Y+ LL I +K G +IFG PGV + + + I I F+ F+TL D+ + W
Sbjct: 5 SKKIQKVIDGIRAWNLSSSSSSTKNEIEETLKSDHFKFGNIVQYGFPNEPTCIAYEPVQKLLVIGTKSGSGRIFGRPGVDHQFQQPSNNSILQIIFLINQGIFLTLCDDDTIHQW 119
BLAST of Protein lethal(2) giant larvae vs. Planmine SMEST
Match: SMESG000025197.1 (SMESG000025197.1) HSP 1 Score: 87.0409 bits (214), Expect = 7.055e-17 Identity = 74/309 (23.95%), Postives = 134/309 (43.37%), Query Frame = 1
Query: 808 AVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKC--LPISKILWKRYK-QDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEY----LLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSS-------NKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWK 1692
+++ ++ P LLIG+ +G ++N+++ S F L L W P NF+ +CH G ++TWN N V+ Q + DQK PI KI+ K ++ ++VFSGG P+ + + ++ + + +L + +IDF + D+ S + + +L + + ++DL ++P + PY LH SP+T ++S+ D+ L S NK ++S +WPI G + ++++I GH DG+I FW+
Sbjct: 191 SIVQMADNPADSNKLLIGFSTGFLSLWNLREKSAKFRFKYAEVLCGLCWYPDG----KNFI-----------------TCHHGGYLVTWNSRVNQGPLTVI--QPHNRDNMDQKIGFEPIRKIVLLTTKSEESIMVFSGGTPKVPNPNSDSTEVSSSFPSVTVMKDKRLTILQMDYPVIDFAQLCDSCSQNCFTDPIGIAILLQNDLMVIDLLSPNYPSFEN--PYPIDLHVSPVTCLHYISDCPGDFVASLYTAKSRIKRPVQNKSQGSMSVHEWPINGGQWGSLLNP--HSEMIITGHADGSIRFWE 472 HSP 2 Score: 51.6026 bits (122), Expect = 3.918e-6 Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 1
Query: 100 SKMTQSIFNSVRKLNFYNFKTKYINQNESI--GEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILW 438
SK Q + + +R N + + N+ E + +K +I +G EP+CI Y+ LL I +K G +IFG PGV + + + I I F+ F+TL D+ + W
Sbjct: 5 SKKIQKVIDGIRAWNLSSSSSSTKNEIEETLKSDHFKFGNIVQYGFPNEPTCIAYEPVQKLLVIGTKSGSGRIFGRPGVDHQFQQPSNNSILQIIFLINQGIFLTLCDDDTIHQW 119
BLAST of Protein lethal(2) giant larvae vs. Planmine SMEST
Match: SMESG000025197.1 (SMESG000025197.1) HSP 1 Score: 86.6557 bits (213), Expect = 7.895e-17 Identity = 74/309 (23.95%), Postives = 134/309 (43.37%), Query Frame = 1
Query: 808 AVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKC--LPISKILWKRYK-QDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEY----LLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSS-------NKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWK 1692
+++ ++ P LLIG+ +G ++N+++ S F L L W P NF+ +CH G ++TWN N V+ Q + DQK PI KI+ K ++ ++VFSGG P+ + + ++ + + +L + +IDF + D+ S + + +L + + ++DL ++P + PY LH SP+T ++S+ D+ L S NK ++S +WPI G + ++++I GH DG+I FW+
Sbjct: 191 SIVQMADNPADSNKLLIGFSTGFLSLWNLREKSAKFRFKYAEVLCGLCWYPDG----KNFI-----------------TCHHGGYLVTWNSRVNQGPLTVI--QPHNRDNMDQKIGFEPIRKIVLLTTKSEESIMVFSGGTPKVPNPNSDSTEVSSSFPSVTVMKDKRLTILQMDYPVIDFAQLCDSCSQNCFTDPIGIAILLQNDLMVIDLLSPNYPSFEN--PYPIDLHVSPVTCLHYISDCPGDFVASLYTAKSRIKRPVQNKSQGSMSVHEWPINGGQWGSLLNP--HSEMIITGHADGSIRFWE 472 HSP 2 Score: 51.9878 bits (123), Expect = 3.543e-6 Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 1
Query: 100 SKMTQSIFNSVRKLNFYNFKTKYINQNESI--GEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILW 438
SK Q + + +R N + + N+ E + +K +I +G EP+CI Y+ LL I +K G +IFG PGV + + + I I F+ F+TL D+ + W
Sbjct: 5 SKKIQKVIDGIRAWNLSSSSSSTKNEIEETLKSDHFKFGNIVQYGFPNEPTCIAYEPVQKLLVIGTKSGSGRIFGRPGVDHQFQQPSNNSILQIIFLINQGIFLTLCDDDTIHQW 119
BLAST of Protein lethal(2) giant larvae vs. Planmine SMEST
Match: SMESG000025197.1 (SMESG000025197.1) HSP 1 Score: 86.6557 bits (213), Expect = 8.499e-17 Identity = 74/309 (23.95%), Postives = 134/309 (43.37%), Query Frame = 1
Query: 808 AVIHISARPGSRKHLLIGYRSGNSIIYNVQKDSVDFLLSAKSTLNALSWCPPDPIVQDNFMVAPNRNEPQYYSSMKLHSCHEDGSIITWNLPQNSDEFLVLDFQIFSPYKKDQKC--LPISKILWKRYK-QDYLIVFSGGLPRSDYMTKSTITIMNNSCLDSSKANNEHLVLDLTSQLIDFTTIDDNDSGSVEY----LLVLTEEEFFIVDLTKESWPILHDRQPYLNCLHNSPITAYQFLSEVKSDWFQKLNEMSS-------NKEDCNISFSDWPIKGYAQKVRNDEIWQNDLLIIGHGDGTIVFWK 1692
+++ ++ P LLIG+ +G ++N+++ S F L L W P NF+ +CH G ++TWN N V+ Q + DQK PI KI+ K ++ ++VFSGG P+ + + ++ + + +L + +IDF + D+ S + + +L + + ++DL ++P + PY LH SP+T ++S+ D+ L S NK ++S +WPI G + ++++I GH DG+I FW+
Sbjct: 191 SIVQMADNPADSNKLLIGFSTGFLSLWNLREKSAKFRFKYAEVLCGLCWYPDG----KNFI-----------------TCHHGGYLVTWNSRVNQGPLTVI--QPHNRDNMDQKIGFEPIRKIVLLTTKSEESIMVFSGGTPKVPNPNSDSTEVSSSFPSVTVMKDKRLTILQMDYPVIDFAQLCDSCSQNCFTDPIGIAILLQNDLMVIDLLSPNYPSFEN--PYPIDLHVSPVTCLHYISDCPGDFVASLYTAKSRIKRPVQNKSQGSMSVHEWPINGGQWGSLLNP--HSEMIITGHADGSIRFWE 472 HSP 2 Score: 51.6026 bits (122), Expect = 3.899e-6 Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 1
Query: 100 SKMTQSIFNSVRKLNFYNFKTKYINQNESI--GEFYKKQSIEDFGSIPEPSCIDYDHKLSLLGIASKKGLIKIFGCPGVCYSTRLEGQDEIWNIKFIPGTNFFVTLTADNKLILW 438
SK Q + + +R N + + N+ E + +K +I +G EP+CI Y+ LL I +K G +IFG PGV + + + I I F+ F+TL D+ + W
Sbjct: 5 SKKIQKVIDGIRAWNLSSSSSSTKNEIEETLKSDHFKFGNIVQYGFPNEPTCIAYEPVQKLLVIGTKSGSGRIFGRPGVDHQFQQPSNNSILQIIFLINQGIFLTLCDDDTIHQW 119 The following BLAST results are available for this feature:
BLAST of Protein lethal(2) giant larvae vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Protein lethal(2) giant larvae vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protein lethal(2) giant larvae vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Protein lethal(2) giant larvae vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein lethal(2) giant larvae vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015890 ID=SMED30015890|Name=Protein lethal(2) giant larvae|organism=Schmidtea mediterranea sexual|type=transcript|length=3417bpback to top protein sequence of SMED30015890-orf-1 >SMED30015890-orf-1 ID=SMED30015890-orf-1|Name=SMED30015890-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1051bp MTQSIFNSVRKLNFYNFKTKYINQNESIGEFYKKQSIEDFGSIPEPSCIDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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