DNA cross-link repair 1C

Overview


Name	DNA cross-link repair 1C
Smed ID	SMED30015874
Length (bp)	1109

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of DNA cross-link repair 1C (SMED30015874) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA cross-link repair 1C (SMED30015874) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA cross-link repair 1C (SMED30015874) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DNA cross-link repair 1C (SMED30015874) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015874

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30015874	SMESG000028344.1	dd_Smed_v6_12096_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
photoreceptor neuron	SMED30015874	SMESG000028344.1	SMED30015874	smed_20140614	PMID:22884275 Lapan et al., 2012
pigment cell	SMED30015874	SMESG000028344.1	SMED30015874	smed_20140614	PMID:22884275 Lapan et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of DNA cross-link repair 1C vs. Ensembl Human
Match: DCLRE1C (DNA cross-link repair 1C [Source:HGNC Symbol;Acc:HGNC:17642])

HSP 1 Score: 139.043 bits (349), Expect = 1.342e-36
Identity = 105/344 (30.52%), Postives = 173/344 (50.29%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFS-KDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAK------NKNK----LFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   +     E      +Y S  T +L+L  + +++    + K   +        + S  D+    K+ I VTL+ +GHC GSVM   +G NG VLYTGDFRL    + ++   +  G    ++  +  +YLDTTF +     IPSRE+    ++ L+   +  S   +++++ K  Y  E L+  +  +  ++VHV+    ++  P  E +       + N++IHAC       + F+ +K      ++N+    + +I P+T+W+ ER+  +N  V    + S R CFS HSS+SEI DF+
Sbjct:    1 MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLT-SPKYR----FWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMP--EILHHLTT--DRNTQIHAC-RHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVR-TGESSYRACFSFHSSYSEIKDFL 329

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BLAST of DNA cross-link repair 1C vs. Ensembl Human
Match: DCLRE1C (DNA cross-link repair 1C [Source:HGNC Symbol;Acc:HGNC:17642])

HSP 1 Score: 137.887 bits (346), Expect = 3.248e-35
Identity = 105/344 (30.52%), Postives = 173/344 (50.29%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFS-KDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAK------NKNK----LFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   +     E      +Y S  T +L+L  + +++    + K   +        + S  D+    K+ I VTL+ +GHC GSVM   +G NG VLYTGDFRL    + ++   +  G    ++  +  +YLDTTF +     IPSRE+    ++ L+   +  S   +++++ K  Y  E L+  +  +  ++VHV+    ++  P  E +       + N++IHAC       + F+ +K      ++N+    + +I P+T+W+ ER+  +N  V    + S R CFS HSS+SEI DF+
Sbjct:    1 MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLT-SPKYR----FWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMP--EILHHLT--TDRNTQIHAC-RHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVR-TGESSYRACFSFHSSYSEIKDFL 329

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BLAST of DNA cross-link repair 1C vs. Ensembl Human
Match: DCLRE1C (DNA cross-link repair 1C [Source:HGNC Symbol;Acc:HGNC:17642])

HSP 1 Score: 93.2041 bits (230), Expect = 5.177e-20
Identity = 65/219 (29.68%), Postives = 113/219 (51.60%), Query Frame = 3

Query:  387 MLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAK------NKNK----LFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            M   +G NG VLYTGDFRL    + ++   +  G    ++  +  +YLDTTF +     IPSRE+    ++ L+   +  S   +++++ K  Y  E L+  +  +  ++VHV+    ++  P  E +       + N++IHAC       + F+ +K      ++N+    + +I P+T+W+ ER+  +N  V    + S R CFS HSS+SEI DF+
Sbjct:    1 MFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMP--EILHHLT--TDRNTQIHACRH-PKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVR-TGESSYRACFSFHSSYSEIKDFL 209

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Query:  387 MLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAK------NKNK----LFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            M   +G NG VLYTGDFRL    + ++   +  G    ++  +  +YLDTTF +     IPSRE+    ++ L+   +  S   +++++ K  Y  E L+  +  +  ++VHV+    ++  P  E +       + N++IHAC       + F+ +K      ++N+    + +I P+T+W+ ER+  +N  V    + S R CFS HSS+SEI DF+
Sbjct:    1 MFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMP--EILHHLT--TDRNTQIHACRH-PKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVR-TGESSYRACFSFHSSYSEIKDFL 209

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Query:  387 MLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAK------NKNK----LFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            M   +G NG VLYTGDFRL    + ++   +  G    ++  +  +YLDTTF +     IPSRE+    ++ L+   +  S   +++++ K  Y  E L+  +  +  ++VHV+    ++  P  E +       + N++IHAC       + F+ +K      ++N+    + +I P+T+W+ ER+  +N  V    + S R CFS HSS+SEI DF+
Sbjct:    1 MFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMP--EILHHLT--TDRNTQIHACRH-PKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVR-TGESSYRACFSFHSSYSEIKDFL 209

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BLAST of DNA cross-link repair 1C vs. Ensembl Celegans
Match: mrt-1 (MoRTal germline [Source:UniProtKB/TrEMBL;Acc:Q8T3E0])

HSP 1 Score: 64.6994 bits (156), Expect = 4.284e-11
Identity = 88/334 (26.35%), Postives = 137/334 (41.02%), Query Frame = 3

Query:  120 FISHLHLDHLCGIENFSASHLTEIYTSDSTAKL---ILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEG------KNGRVLYTGDFRLN------LENSNQLS--SDYKYGIKIMKINYLDGLY--LDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKV---RYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQ 1055
            F++H H DH  G++         +Y S  TAKL   I+G  ++       + PL      ++  K+         D   VTL+++ HC G+VM   EG        G VL TGDFR +      L+  NQL   ++ K+GI      YLD  Y  LD  F  +C A                EKILL++++     +  +   R   E L   I    N  + V    Y + K + + + F       N  +   Y D    K     +       I  + L+++  N V++      D+  +R+ +S HSS SEI+ F+   H K+I  C  +
Sbjct:  238 FLTHAHSDHYRGLDK---KWTRSVYCSPETAKLLPHIMGYTADSPPPAGLINPL----EENVPHKF---------DSFQVTLVNANHCPGAVMFVFEGSKIEEIAGGAVLCTGDFRADKMFLESLKPGNQLHWMTEIKFGII-----YLDNTYFSLDMPFPERCEA----------------EKILLKAIEAHPHENIVIPLHRLGREELIQAISRILNEPIMV----YDERKVISDLLDFSS-----NCGVLKQYRDIKVIKKGSYCEISQNSVIIDISMLYYTFGNGVND------DEGIIRIPYSDHSSRSEILKFLSHFHFKTITPCTKK 519

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Query:  120 FISHLHLDHLCGIENFSASHLTEIYTSDSTAKL---ILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEG------KNGRVLYTGDFRLN------LENSNQLS--SDYKYGIKIMKINYLDGLY--LDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKV---RYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQ 1055
            F++H H DH  G++         +Y S  TAKL   I+G  ++       + PL      ++  K+         D   VTL+++ HC G+VM   EG        G VL TGDFR +      L+  NQL   ++ K+GI      YLD  Y  LD  F  +C A                EKILL++++     +  +   R   E L   I    N  + V    Y + K + + + F       N  +   Y D    K     +       I  + L+++  N V++      D+  +R+ +S HSS SEI+ F+   H K+I  C  +
Sbjct:  238 FLTHAHSDHYRGLDK---KWTRSVYCSPETAKLLPHIMGYTADSPPPAGLINPL----EENVPHKF---------DSFQVTLVNANHCPGAVMFVFEGSKIEEIAGGAVLCTGDFRADKMFLESLKPGNQLHWMTEIKFGII-----YLDNTYFSLDMPFPERCEA----------------EKILLKAIEAHPHENIVIPLHRLGREELIQAISRILNEPIMV----YDERKVISDLLDFSS-----NCGVLKQYRDIKVIKKGSYCEISQNSVIIDISMLYYTFGNGVND------DEGIIRIPYSDHSSRSEILKFLSHFHFKTITPCTKK 519

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BLAST of DNA cross-link repair 1C vs. Ensembl Fly
Match: Snm1 (gene:FBgn0037338 transcript:FBtr0078688)

HSP 1 Score: 55.4546 bits (132), Expect = 4.330e-8
Identity = 45/149 (30.20%), Postives = 74/149 (49.66%), Query Frame = 3

Query:  108 VSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGR-VLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNK 551
            V+ YF++H H DH  G+   +      +Y S  +A+L+            ++K   L +++  +I   D DQ    D + VT + + HC G++M F +  +G  +L+TGDFR         S+D +        + +D LYLDTT+MNK
Sbjct:  288 VTHYFLTHFHADHYIGL---TKKFCHPLYVSPISARLVRT----------FIK---LDETHIHEI---DVDQTLDVDGVQVTALEANHCPGALMFFFKLSSGECILHTGDFR--------ASADMESLPIFWNHSNIDLLYLDTTYMNK 409

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BLAST of DNA cross-link repair 1C vs. Ensembl Zebrafish
Match: dclre1c (DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) [Source:NCBI gene;Acc:566285])

HSP 1 Score: 140.198 bits (352), Expect = 2.750e-36
Identity = 110/356 (30.90%), Postives = 177/356 (49.72%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIEN------FSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKL--------------FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F+G + EYP I++D F   N     YF+SH H DH+ G++          S   ++Y S  T +L+L  N  +     ++ PL L    SI +   D     ++D++ VTL+S+GHC GSVM   EG  G VLYTGDFRL + ++ ++    +Y     ++  +  +Y+DTTF +     IPSRE     I  L++  + +S   +++++ K  Y  E L+  +  +FN ++HV+    ++  P       C    N  ++IHAC    H +   EE    N+L               +I P+T+W+ ER   ++  V  +   S R CFS HSS+ E+ DF+  +   +IY
Sbjct:    1 MSSFAGRMKEYPSISLDRFDRENLHARAYFLSHCHKDHMKGLKGPLLKRKLKFSLTVKLYCSYVTKELLLS-NPRYAFWEDHIVPLELDSPTSISL--IDESTGETEDVV-VTLLSAGHCPGSVMFLFEGAKGTVLYTGDFRLAVGDAARM----EYLHSGDRVKDIQSVYIDTTFFDPKYYQIPSREACLAGIQQLVQDWICQSPYHVVWLNCKAAYGYEYLFTNLGQEFNSQIHVNSLDMFKKMPE----ILCHVTTNRATQIHAC---RHPKD--EEFFRANRLPCGSTAPDGIPLNIISIKPSTIWFGERTRKTSVVVK-MGSSSYRACFSFHSSYLEVKDFLSYICPVNIY 338

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Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIEN------FSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKL--------------FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F+G + EYP I++D F   N     YF+SH H DH+ G++          S   ++Y S  T +L+L  N  +     ++ PL L    SI +   D     ++D++ VTL+S+GHC GSVM   EG  G VLYTGDFRL + ++ ++    +Y     ++  +  +Y+DTTF +     IPSRE     I  L++  + +S   +++++ K  Y  E L+  +  +FN ++HV+    ++  P       C    N  ++IHAC    H +   EE    N+L               +I P+T+W+ ER   ++  V  +   S R CFS HSS+ E+ DF+  +   +IY
Sbjct:    1 MSSFAGRMKEYPSISLDRFDRENLHARAYFLSHCHKDHMKGLKGPLLKRKLKFSLTVKLYCSYVTKELLLS-NPRYAFWEDHIVPLELDSPTSISL--IDESTGETEDVV-VTLLSAGHCPGSVMFLFEGAKGTVLYTGDFRLAVGDAARM----EYLHSGDRVKDIQSVYIDTTFFDPKYYQIPSREACLAGIQQLVQDWICQSPYHVVWLNCKAAYGYEYLFTNLGQEFNSQIHVNSLDMFKKMPE----ILCHVTTNRATQIHAC---RHPKD--EEFFRANRLPCGSTAPDGIPLNIISIKPSTIWFGERTRKTSVVVK-MGSSSYRACFSFHSSYLEVKDFLSYICPVNIY 338

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BLAST of DNA cross-link repair 1C vs. Ensembl Zebrafish
Match: dclre1c (DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) [Source:NCBI gene;Acc:566285])

HSP 1 Score: 117.087 bits (292), Expect = 3.104e-28
Identity = 101/356 (28.37%), Postives = 166/356 (46.63%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIEN------FSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKL--------------FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F+G + EYP I++D F   N     YF+SH H DH+ G++          S   ++Y S  T +L+L  N  +     ++ PL L    +I +   D     ++D++ VTL+S+GHC GSVM   EG  G VLYTGDFRL + ++ +                ++ L+    F +K    +P  E     I  L++  + +S   +++++ K  Y  E L+  +  +F+ ++HV+    ++  P       C    N  ++IHAC          EE    N+L               +I P+T+W+ ER   ++  V  +   S R CFS HSS+ E+ DF+  +   +IY
Sbjct:    1 MSSFAGRMKEYPSISLDRFDRENLHARAYFLSHCHKDHMKGLKGPLLKRKLKFSLTVKLYCSYVTKELLLS-NPRYAFWEDHIVPLELDSPTNISL--IDESTGETEDVV-VTLLSAGHCPGSVMFLFEGAKGTVLYTGDFRLAVGDAAR----------------MEYLHSGDRFSDKDFFKMPHLEACLAGIQQLVQDWICQSPYHVVWLNCKAAYGYEYLFTNLGQEFSSQIHVNSLDMFKKMPE----ILCHVTTNRATQIHACR-----HPKDEEFFRANRLPCGSTAPDGIPLNIISIKPSTIWFGERTRKTSVVVK-MGSSSYRACFSFHSSYLEVKDFLSYICPVNIY 326

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BLAST of DNA cross-link repair 1C vs. Ensembl Zebrafish
Match: dclre1b (DNA cross-link repair 1B [Source:NCBI gene;Acc:768137])

HSP 1 Score: 77.0258 bits (188), Expect = 5.708e-15
Identity = 84/310 (27.10%), Postives = 135/310 (43.55%), Query Frame = 3

Query:  108 VSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYL------DGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTL--EALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            V  +F+SH+H DH CG+ + + SH   IY S  TAKL+     + +    +++PL +G+ + + +          K+ + V LI + HC G+VM   +G  G  LYTGDFR              Y   ++++  L      D LYLD T  +   A +PSR+ +       I++I+ +     + I     Y+L  E+L   + ++F   V VD +    L+ L     F  D  +   RI           N            I+PT+     R +VS     Y+      V +S HSS+ E+ DF+
Sbjct:   24 VRLFFLSHMHSDHTCGLSS-TWSH-RPIYCSPLTAKLL---RLKLQIKQKWIRPLEIGQDHMLML------DDLGKERLTVNLIDANHCPGAVMFLFQGYFGTRLYTGDFR--------------YTPSMLRVPCLQNHINIDVLYLDNTNCDPTRA-LPSRQQA----TQQIKQIIRDHPGYAVVIGL---YSLGKESLLVDLAMEFKTWVEVDRERLETLRVLQLPDVFTTD--SGAGRIRVVNQSMISASNLMAWNKLQSTIAILPTS-----RPMVSCHPNVYV------VPYSDHSSYQELEDFV 287

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Query:  108 VSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYL------DGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTL--EALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            V  +F+SH+H DH CG+ + + SH   IY S  TAKL+     + +    +++PL +G+ + + +          K+ + V LI + HC G+VM   +G  G  LYTGDFR              Y   ++++  L      D LYLD T  +   A +PSR+ +       I++I+ +     + I     Y+L  E+L   + ++F   V VD +    L+ L     F  D  +   RI           N            I+PT+     R +VS     Y+      V +S HSS+ E+ DF+
Sbjct:   24 VRLFFLSHMHSDHTCGLSS-TWSH-RPIYCSPLTAKLL---RLKLQIKQKWIRPLEIGQDHMLML------DDLGKERLTVNLIDANHCPGAVMFLFQGYFGTRLYTGDFR--------------YTPSMLRVPCLQNHINIDVLYLDNTNCDPTRA-LPSRQQA----TQQIKQIIRDHPGYAVVIGL---YSLGKESLLVDLAMEFKTWVEVDRERLETLRVLQLPDVFTTD--SGAGRIRVVNQSMISASNLMAWNKLQSTIAILPTS-----RPMVSCHPNVYV------VPYSDHSSYQELEDFV 287

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Xenopus
Match: DCLRE1C (DNA cross-link repair 1C [Source:NCBI gene;Acc:100493603])

HSP 1 Score: 133.265 bits (334), Expect = 3.294e-34
Identity = 107/354 (30.23%), Postives = 170/354 (48.02%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIE------NFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM---DSHCRKN------FEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCV 1049
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+           S    +Y S  T +L+L   +  K      + + +      +I   D    + +D++ VTL+ +GHC GSVM   +G +G VLYTGDFRL      ++   +       ++  ++ +YLDTTF +     IPSRE+    I+ L+   +  S   +++++ K  Y  E L+  +  +F  KVHV+    ++  P  E +S      +  ++IHAC     +   R N      F +      + +I P+T+W+ ER   +N  V    + S R CFS HSS+SEI DF+  +   ++Y  V
Sbjct:    1 MSSFMGRMKEYPAISIDRFDRENLSARAYFLSHCHKDHMKGLRAPFLKRRLQNSLKVHLYCSPVTKELLL---TNPKYAFWENRMISIEIDTPTQISLVDEATGYKEDVV-VTLLPAGHCPGSVMFLFQGNSGTVLYTGDFRLAKGEVARMELLHSGN----RLKDIESVYLDTTFCDPKYYQIPSREECLSGILELVRSWITLSPFHVVWLNCKAAYGYEYLFTNLSEEFGAKVHVNKLDMFKNMP--EILSHIT--TDRRTQIHACRHPVNEEFTRANRMPCGMFSDDGIPLHVISIKPSTIWFGERTRRTNVIVR-TGESSYRACFSFHSSYSEIKDFLGYIKPMNVYANV 341

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Xenopus
Match: DCLRE1C (DNA cross-link repair 1C [Source:NCBI gene;Acc:100493603])

HSP 1 Score: 132.88 bits (333), Expect = 1.455e-33
Identity = 107/354 (30.23%), Postives = 170/354 (48.02%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIE------NFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM---DSHCRKN------FEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCV 1049
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+           S    +Y S  T +L+L   +  K      + + +      +I   D    + +D++ VTL+ +GHC GSVM   +G +G VLYTGDFRL      ++   +       ++  ++ +YLDTTF +     IPSRE+    I+ L+   +  S   +++++ K  Y  E L+  +  +F  KVHV+    ++  P  E +S      +  ++IHAC     +   R N      F +      + +I P+T+W+ ER   +N  V    + S R CFS HSS+SEI DF+  +   ++Y  V
Sbjct:    1 MSSFMGRMKEYPAISIDRFDRENLSARAYFLSHCHKDHMKGLRAPFLKRRLQNSLKVHLYCSPVTKELLL---TNPKYAFWENRMISIEIDTPTQISLVDEATGYKEDVV-VTLLPAGHCPGSVMFLFQGNSGTVLYTGDFRLAKGEVARMELLHSGN----RLKDIESVYLDTTFCDPKYYQIPSREECLSGILELVRSWITLSPFHVVWLNCKAAYGYEYLFTNLSEEFGAKVHVNKLDMFKNMP--EILSHIT--TDRRTQIHACRHPVNEEFTRANRMPCGMFSDDGIPLHVISIKPSTIWFGERTRRTNVIVR-TGESSYRACFSFHSSYSEIKDFLGYIKPMNVYANV 341

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Xenopus
Match: DCLRE1C (DNA cross-link repair 1C [Source:NCBI gene;Acc:100493603])

HSP 1 Score: 132.88 bits (333), Expect = 1.752e-33
Identity = 107/356 (30.06%), Postives = 173/356 (48.60%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIE------NFSASHLTEIYTSDSTAKLIL--GRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM---DSHCRKN------FEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCV 1049
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+           S    +Y S  T +L+L   + + ++N +     + +      +I   D    + +D++ VTL+ +GHC GSVM   +G +G VLYTGDFRL      ++   +       ++  ++ +YLDTTF +     IPSRE+    I+ L+   +  S   +++++ K  Y  E L+  +  +F  KVHV+    ++  P  E +S      +  ++IHAC     +   R N      F +      + +I P+T+W+ ER   +N  V    + S R CFS HSS+SEI DF+  +   ++Y  V
Sbjct:    1 MSSFMGRMKEYPAISIDRFDRENLSARAYFLSHCHKDHMKGLRAPFLKRRLQNSLKVHLYCSPVTKELLLTNPKYAFWENRM-----ISIEIDTPTQISLVDEATGYKEDVV-VTLLPAGHCPGSVMFLFQGNSGTVLYTGDFRLAKGEVARMELLHSGN----RLKDIESVYLDTTFCDPKYYQIPSREECLSGILELVRSWITLSPFHVVWLNCKAAYGYEYLFTNLSEEFGAKVHVNKLDMFKNMP--EILSHIT--TDRRTQIHACRHPVNEEFTRANRMPCGMFSDDGIPLHVISIKPSTIWFGERTRRTNVIVR-TGESSYRACFSFHSSYSEIKDFLGYIKPMNVYANV 341

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Xenopus
Match: DCLRE1C (DNA cross-link repair 1C [Source:NCBI gene;Acc:100493603])

HSP 1 Score: 132.88 bits (333), Expect = 1.840e-33
Identity = 107/354 (30.23%), Postives = 170/354 (48.02%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIE------NFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM---DSHCRKN------FEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCV 1049
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+           S    +Y S  T +L+L   +  K      + + +      +I   D    + +D++ VTL+ +GHC GSVM   +G +G VLYTGDFRL      ++   +       ++  ++ +YLDTTF +     IPSRE+    I+ L+   +  S   +++++ K  Y  E L+  +  +F  KVHV+    ++  P  E +S      +  ++IHAC     +   R N      F +      + +I P+T+W+ ER   +N  V    + S R CFS HSS+SEI DF+  +   ++Y  V
Sbjct:    1 MSSFMGRMKEYPAISIDRFDRENLSARAYFLSHCHKDHMKGLRAPFLKRRLQNSLKVHLYCSPVTKELLL---TNPKYAFWENRMISIEIDTPTQISLVDEATGYKEDVV-VTLLPAGHCPGSVMFLFQGNSGTVLYTGDFRLAKGEVARMELLHSGN----RVKDIESVYLDTTFCDPKYYQIPSREECLSGILELVRSWITLSPFHVVWLNCKAAYGYEYLFTNLSEEFGAKVHVNKLDMFKNMP--EILSHIT--TDRRTQIHACRHPVNEEFTRANRMPCGMFSDDGIPLHVISIKPSTIWFGERTRRTNVIVR-TGESSYRACFSFHSSYSEIKDFLGYIKPMNVYANV 341

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Xenopus
Match: DCLRE1C (DNA cross-link repair 1C [Source:NCBI gene;Acc:100493603])

HSP 1 Score: 129.028 bits (323), Expect = 3.349e-32
Identity = 109/364 (29.95%), Postives = 176/364 (48.35%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIE------NFSASHLTEIYTSDSTAKLIL--GRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM---DSHCRKN------FEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSE-IIDFILKVHSKSIYYCVSQTCNTL 1070
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+           S    +Y S  T +L+L   + + ++N     + + +      +I   D    + +D++ VTL+ +GHC GSVM   +G +G VLYTGDFRL      ++   +       ++  ++ +YLDTTF +     IPSRE+    I+ L+   +  S   +++++ K  Y  E L+  +  +F  KVHV+    ++  P  E +S      +  ++IHAC     +   R N      F +      + +I P+T+W+ ER   +N  V    + S R CFS HSS+SE I++  L  +++     V QTC T 
Sbjct:    1 MSSFMGRMKEYPAISIDRFDRENLSARAYFLSHCHKDHMKGLRAPFLKRRLQNSLKVHLYCSPVTKELLLTNPKYAFWEN-----RMISIEIDTPTQISLVDEATGYKEDVV-VTLLPAGHCPGSVMFLFQGNSGTVLYTGDFRLAKGEVARMELLHSGN----RVKDIESVYLDTTFCDPKYYQIPSREECLSGILELVRSWITLSPFHVVWLNCKAAYGYEYLFTNLSEEFGAKVHVNKLDMFKNMP--EILSHIT--TDRRTQIHACRHPVNEEFTRANRMPCGMFSDDGIPLHVISIKPSTIWFGERTRRTNVIVR-TGESSYRACFSFHSSYSELIVNDRLLCYAEVYINPVFQTCKTF 349

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Mouse
Match: Dclre1c (DNA cross-link repair 1C [Source:MGI Symbol;Acc:MGI:2441769])

HSP 1 Score: 144.05 bits (362), Expect = 3.071e-38
Identity = 110/345 (31.88%), Postives = 169/345 (48.99%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLIL--GRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFE--------EAKNKNKLFTII--PTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   S     E      +Y S  T +L+L   +   ++N +     + +      +I   D      ++++ VTL+ +GHC GSVM   +G NG VLYTGDFRL    ++++   +  G    ++  +  +YLDTTF +     IPSRE     I+ L+   +  S   +++++ K  Y  E L+  +  +  ++VHVD    ++  P D       D    N++IHAC       + F+         ++NK  L TI   P+T+W+ ER   +N  V    + S R CFS HSSFSEI DF+
Sbjct:    1 MSSFQGQMAEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELLLTSPKYRFWENRI-----ITIEIETPTQISLVDEASGEKEEVV-VTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEASRMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREQCLRGILELVRSWVTRSPHHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMP-DILHHLTTDR---NTQIHAC-RHPKAEECFQWNKLPCGITSQNKTALHTISIKPSTMWFGERTRKTNVIVR-TGESSYRACFSFHSSFSEIKDFL 329

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Mouse
Match: Dclre1c (DNA cross-link repair 1C [Source:MGI Symbol;Acc:MGI:2441769])

HSP 1 Score: 143.665 bits (361), Expect = 1.180e-37
Identity = 110/345 (31.88%), Postives = 169/345 (48.99%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLIL--GRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFE--------EAKNKNKLFTII--PTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   S     E      +Y S  T +L+L   +   ++N +     + +      +I   D      ++++ VTL+ +GHC GSVM   +G NG VLYTGDFRL    ++++   +  G    ++  +  +YLDTTF +     IPSRE     I+ L+   +  S   +++++ K  Y  E L+  +  +  ++VHVD    ++  P D       D    N++IHAC       + F+         ++NK  L TI   P+T+W+ ER   +N  V    + S R CFS HSSFSEI DF+
Sbjct:    1 MSSFQGQMAEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELLLTSPKYRFWENRI-----ITIEIETPTQISLVDEASGEKEEVV-VTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEASRMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREQCLRGILELVRSWVTRSPHHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMP-DILHHLTTD---RNTQIHAC-RHPKAEECFQWNKLPCGITSQNKTALHTISIKPSTMWFGERTRKTNVIVR-TGESSYRACFSFHSSFSEIKDFL 329

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Mouse
Match: Dclre1c (DNA cross-link repair 1C [Source:MGI Symbol;Acc:MGI:2441769])

HSP 1 Score: 142.895 bits (359), Expect = 4.854e-37
Identity = 110/345 (31.88%), Postives = 168/345 (48.70%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLILGRNSE--FKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFE--------EAKNKNKLFTII--PTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   S     E      +Y S  T +L+L       ++N +     + +      +I   D      ++++ VTL+ +GHC GSVM   +G NG VLYTGDFRL    ++++   +  G    ++  +  +YLDTTF +     IPSRE     I+ L+   +  S   +++++ K  Y  E L+  +  +  ++VHVD    ++  P D       D    N++IHAC       + F+         ++NK  L TI   P+T+W+ ER   +N  V    + S R CFS HSSFSEI DF+
Sbjct:    1 MSSFQGQMAEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELLLTSPKYRFWENRI-----ITIEIETPTQISLVDEASGEKEEVV-VTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEASRMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREQCLRGILELVRSWVTRSPHHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMP-DILHHLTTD---RNTQIHACRH-PKAEECFQWNKLPCGITSQNKTALHTISIKPSTMWFGERTRKTNVIVR-TGESSYRACFSFHSSFSEIKDFL 329

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Mouse
Match: Dclre1b (DNA cross-link repair 1B [Source:MGI Symbol;Acc:MGI:2156057])

HSP 1 Score: 79.7221 bits (195), Expect = 7.911e-16
Identity = 86/339 (25.37%), Postives = 146/339 (43.07%), Query Frame = 3

Query:   51 FSGIIYEYPQIAIDNFN----PLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQ 1055
             +G++     IA+D ++         +F++H+H DH  G+   S++    +Y S  TA L+  R    K+   +++ L +G+S+ + +          ++ + VTLI + HC GSVM   EG  G +LYTGDFR          S  K    I+    +  LYLD T  N     +PSR+++   I+ LI +    ++   ++   K     E+L   + L+F   V +  +    ++ L  +  F V+      RIHA      C     +    +    I PT+     R + S     Y       V +S HSS+SE+  F+  +    +   V Q
Sbjct:    1 MNGVVIPQTPIAVDFWSLRRAGSARLFFLTHMHCDHTVGL---SSTWARPLYCSPITACLLHRRLQVSKH---WIRALEVGESHVLPLDE------IGQETMTVTLIDANHCPGSVMFLFEGYFGTILYTGDFRYT-------PSMLKEPALILG-KQIHTLYLDNTNCNPALV-LPSRQEATQQIVQLIRQFPQHNIKIGLYSLGK-----ESLLEQLALEFRTWVVLSPQRLELVQLLGLADVFTVE--EEAGRIHAVDHTEICHSAMLQWNQSHPTIAIFPTS-----RKVRSPHPSIYT------VPYSDHSSYSELRAFVAALRPCQVVPIVHQ 300

[Close]

Query:   51 FSGIIYEYPQIAIDNFN----PLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQ 1055
             +G++     IA+D ++         +F++H+H DH  G+   S++    +Y S  TA L+  R    K+   +++ L +G+S+ + +          ++ + VTLI + HC GSVM   EG  G +LYTGDFR          S  K    I+    +  LYLD T  N     +PSR+++   I+ LI +    ++   ++   K     E+L   + L+F   V +  +    ++ L  +  F V+      RIHA      C     +    +    I PT+     R + S     Y       V +S HSS+SE+  F+  +    +   V Q
Sbjct:    1 MNGVVIPQTPIAVDFWSLRRAGSARLFFLTHMHCDHTVGL---SSTWARPLYCSPITACLLHRRLQVSKH---WIRALEVGESHVLPLDE------IGQETMTVTLIDANHCPGSVMFLFEGYFGTILYTGDFRYT-------PSMLKEPALILG-KQIHTLYLDNTNCNPALV-LPSRQEATQQIVQLIRQFPQHNIKIGLYSLGK-----ESLLEQLALEFRTWVVLSPQRLELVQLLGLADVFTVE--EEAGRIHAVDHTEICHSAMLQWNQSHPTIAIFPTS-----RKVRSPHPSIYT------VPYSDHSSYSELRAFVAALRPCQVVPIVHQ 300

[Close]

BLAST of DNA cross-link repair 1C vs. UniProt/SwissProt
Match: sp|Q8K4J0|DCR1C_MOUSE (Protein artemis OS=Mus musculus OX=10090 GN=Dclre1c PE=1 SV=2)

HSP 1 Score: 142.895 bits (359), Expect = 3.395e-36
Identity = 110/345 (31.88%), Postives = 168/345 (48.70%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLILGRNSE--FKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFE--------EAKNKNKLFTII--PTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   S     E      +Y S  T +L+L       ++N +     + +      +I   D      ++++ VTL+ +GHC GSVM   +G NG VLYTGDFRL    ++++   +  G    ++  +  +YLDTTF +     IPSRE     I+ L+   +  S   +++++ K  Y  E L+  +  +  ++VHVD    ++  P D       D    N++IHAC       + F+         ++NK  L TI   P+T+W+ ER   +N  V    + S R CFS HSSFSEI DF+
Sbjct:    1 MSSFQGQMAEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELLLTSPKYRFWENRI-----ITIEIETPTQISLVDEASGEKEEVV-VTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEASRMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREQCLRGILELVRSWVTRSPHHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMP-DILHHLTTD---RNTQIHACRH-PKAEECFQWNKLPCGITSQNKTALHTISIKPSTMWFGERTRKTNVIVR-TGESSYRACFSFHSSFSEIKDFL 329

[Close]

BLAST of DNA cross-link repair 1C vs. UniProt/SwissProt
Match: sp|Q5QJC2|DCR1C_CHICK (Protein artemis OS=Gallus gallus OX=9031 GN=DCLRE1C PE=2 SV=1)

HSP 1 Score: 141.354 bits (355), Expect = 1.269e-35
Identity = 112/351 (31.91%), Postives = 177/351 (50.43%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIE------NFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM---DSHCRKNFEE----AKNKNKL--FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F G + EYPQ++ID F   N     YF+SH H DH+ G+          +S   ++Y S  T +L+L  NS++     ++  L +     I +    ++    K+ I VTL+ +GHC GSVM   +G+NG VLYTGDFRL    + ++   +  G  +  I     +YLDTTF +    HIPSRE+    I+ L+      S   +++++ K  Y  E L+  +  +  IKVHV+    ++  P    I + +    + ++IHAC     D + R N        +N   L   +I P+T+W+ ER   +N  V    + + R CFS HSS+SEI+DF+  +   ++Y
Sbjct:    1 MSRFGGRLREYPQLSIDRFDYDNLRARAYFLSHCHKDHMKGLRAPALRRRLQSSLKVKLYCSPVTKELLL-TNSKYAFWENHIVALEVETPTQISLV---DETTGEKEDIEVTLLPAGHCPGSVMFLFQGENGTVLYTGDFRLAKGEAARMELLHS-GTSVKDIQ---SVYLDTTFCDPRFYHIPSREECLSGILELVRSWTTLSRYHVVWLNCKAAYGYEYLFINLSEELGIKVHVNKLDMFKNMP---EILYHITTDRY-TQIHACRHPKDDDYVRGNRLPCGITCQNGTPLHVISIKPSTMWFGERIKKTNVIVR-TGESTYRACFSFHSSYSEIMDFLSYIRPVNVY 338

[Close]

BLAST of DNA cross-link repair 1C vs. UniProt/SwissProt
Match: sp|Q5RGE5|DCR1C_DANRE (Protein artemis OS=Danio rerio OX=7955 GN=dclre1c PE=2 SV=1)

HSP 1 Score: 140.198 bits (352), Expect = 2.076e-35
Identity = 110/356 (30.90%), Postives = 177/356 (49.72%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIEN------FSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKL--------------FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F+G + EYP I++D F   N     YF+SH H DH+ G++          S   ++Y S  T +L+L  N  +     ++ PL L    SI +   D     ++D++ VTL+S+GHC GSVM   EG  G VLYTGDFRL + ++ ++    +Y     ++  +  +Y+DTTF +     IPSRE     I  L++  + +S   +++++ K  Y  E L+  +  +FN ++HV+    ++  P       C    N  ++IHAC    H +   EE    N+L               +I P+T+W+ ER   ++  V  +   S R CFS HSS+ E+ DF+  +   +IY
Sbjct:    1 MSSFAGRMKEYPSISLDRFDRENLHARAYFLSHCHKDHMKGLKGPLLKRKLKFSLTVKLYCSYVTKELLLS-NPRYAFWEDHIVPLELDSPTSISL--IDESTGETEDVV-VTLLSAGHCPGSVMFLFEGAKGTVLYTGDFRLAVGDAARM----EYLHSGDRVKDIQSVYIDTTFFDPKYYQIPSREACLAGIQQLVQDWICQSPYHVVWLNCKAAYGYEYLFTNLGQEFNSQIHVNSLDMFKKMPE----ILCHVTTNRATQIHAC---RHPKD--EEFFRANRLPCGSTAPDGIPLNIISIKPSTIWFGERTRKTSVVVK-MGSSSYRACFSFHSSYLEVKDFLSYICPVNIY 338

[Close]

BLAST of DNA cross-link repair 1C vs. UniProt/SwissProt
Match: sp|Q5XIX3|DCR1C_RAT (Protein artemis OS=Rattus norvegicus OX=10116 GN=Dclre1c PE=1 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 5.531e-35
Identity = 110/348 (31.61%), Postives = 167/348 (47.99%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSD-----NDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFE--------EAKNKNKLFTII--PTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   S     E      +Y S  T +L+L          P  K     +  +I+I+        ++    K+ + VTL+ +GHC GSVM   +G NG VLYTGDFRL     +++   +  G    ++  +  +YLDTTF +     IPSRE+    ++ L+   +  S   +++++ K  Y  E L+  +  +  ++VHVD    ++  P D       D    N++IHAC       + F+         +K K  L TI   P+T+W+ ER   +N  V    + S R CFS HSS+SEI DF+
Sbjct:    1 MSSFQGQMEEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSMKRRLECSLKVFLYCSPVTKELLL--------TSPKYK-FWENRIIAIEIETPTQVSLVDEASGEKEEVVVTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEVSRMELLHSGG----RVKDIQSVYLDTTFCDPRFYQIPSREECLRGVLELVRSWITRSPKHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMP-DILHHLTTD---RNTQIHACRH-PKAEEYFQWNKLPCGMASKTKTVLHTISIKPSTMWFGERTRKTNVIVR-TGESSYRACFSFHSSYSEIKDFL 329

[Close]

BLAST of DNA cross-link repair 1C vs. UniProt/SwissProt
Match: sp|Q5R6Z9|DCR1C_PONAB (Protein artemis OS=Pongo abelii OX=9601 GN=DCLRE1C PE=2 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 7.569e-35
Identity = 107/344 (31.10%), Postives = 173/344 (50.29%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE------IYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFS-KDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAK------NKNK----LFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFI 1013
            MS F G + EYP I+ID F   N     YF+SH H DH+ G+   +     E      +Y S  T +L+L  + +++    + K   +        + S  D+    K+ I VTL+ +GHC GSVM   +G NG VLYTGDFRL    + ++   +  G    +I  +  +YLDTTF +     IPSRE+    I+ L+   +  S   +++++ K  Y  E L+  +  +  ++VHV+    ++  P  E +       + N++IHAC       + F+ +K      ++N+    + +I P+T+W+ ER+  +N  V    + S R CFS HSS+SEI DF+
Sbjct:    1 MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLT-SPKYR----FWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGG----RIKDIQSVYLDTTFCDPRFYQIPSREECLSGILELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMP--EILHHLT--TDRNTQIHAC-RHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVR-TGESSYRACFSFHSSYSEIKDFL 329

[Close]

BLAST of DNA cross-link repair 1C vs. TrEMBL
Match: C3YPJ3 (DRMBL domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_215154 PE=4 SV=1)

HSP 1 Score: 164.851 bits (416), Expect = 1.573e-43
Identity = 115/364 (31.59%), Postives = 189/364 (51.92%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIEN------FSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKD-IINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSH-----CRKNFEEAKNKNKLFTIIPTTLWWS----ERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 1076
            MS F G + EY  ++ID F   N     +F+SH H DH+ G++N        AS  T +Y SD T  L+L    +FK + PY+  + +    S+ +     D+   K+  + VTL+ +GHC GSVM   EG  G VLYTGDFRL +  + Q    ++ G ++  I     LY+DTTF+     +IPSRED    +IN+++  + +    ++ ++ K +Y  E L+  +  +FN+KVHV+  S YQ  P    I  C+      ++IHAC          C K      ++ ++ ++ P+T+W++      +++     H+      RVCFS HSS++EI DF+  +  K+++  V+    TL++
Sbjct:    1 MSCFGGRMSEYRYLSIDRFDGENLESWAFFLSHAHRDHMVGLDNPGFLSRLKASLKTRLYCSDITKALLL-TEKQFKPLEPYIVSVQIDTPTSLTV----TDEVTGKEHSLLVTLLQAGHCPGSVMFLFEGLEGTVLYTGDFRLPVGGAAQFQHLHQ-GDRLKDIQ---SLYVDTTFLVPEAKYIPSREDCCTALINVVQSWISKGAHYVVRMNCKAKYGYEYLFIELCRRFNMKVHVNDPSVYQAIP---EIFQCLTSDPSETQIHACRYQKGRHPLPC-KYRPPPPHELEVMSVTPSTMWFTAYAGPGDVIRKGSRHHH-----RVCFSFHSSYTEIRDFVGYIRPKTVHANVAPVGTTLEE 346

[Close]

BLAST of DNA cross-link repair 1C vs. TrEMBL
Match: S4RFM2 (DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) OS=Petromyzon marinus OX=7757 PE=4 SV=1)

HSP 1 Score: 164.851 bits (416), Expect = 4.608e-43
Identity = 115/355 (32.39%), Postives = 183/355 (51.55%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGI------ENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKP--LDESISFCVDPCNWNSRIHACYMDSH----------CRKNFEEAKNKN-KLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F G   EYP ++ID F   N     +F+SH H DH+ G+      +    S    +Y S  T +L+L  N  ++ +  +   + +    + +I  +D+      D++ VTL+ +GHC GSVM   EG +G VLYTGDFRL     +++ + +  G    +I  +  +YLDTTF +  C +IPSRED    I+NL+   + +S   +I+++ K  Y  E L+  +  +F  KVH+     +Q  P  LD          + N++IHAC +             CR+  ++AK K+  + +I P+T+W+++RN    K +    + S R CFS HSSFSEI DFI  +   +I+
Sbjct:    1 MSSFLGKTAEYPSVSIDRFDRDNVDARAFFLSHCHQDHMVGLYSEALRKKLERSPGVHLYCSPVTRELLLS-NWRYRFLERFT--VAIEVDTATQISLTDDKTKQKTDLV-VTLLPAGHCPGSVMFLFEGDHGAVLYTGDFRLPRGGVSRMGALHSAG----RIKRIKSIYLDTTFCDPMCYYIPSREDCLKGILNLVRGWITQSPQHVIWLNCKAAYGYEYLFTHLSREFGQKVHLGYLEMFQNMPDILDHVTH------DSNTQIHACRIPKDAGICEGRRLPCRE--KDAKGKSLHMMSIKPSTMWFTQRN-KKTKIIVRTGESSYRACFSFHSSFSEIEDFISYIKPANIF 338

[Close]

BLAST of DNA cross-link repair 1C vs. TrEMBL
Match: V4A3J4 (DRMBL domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_209646 PE=4 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 2.753e-40
Identity = 115/347 (33.14%), Postives = 176/347 (50.72%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGI------ENFSASHLTEIYTSDSTAKLILGRNS-EFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDY-KYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHV-DIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSV--RVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F G + EY +I+ID F   N L S +F+SH H DH+ G+      +   A +   +Y SD +  L+LG N+  F ++ PY+K L + +  +I I    N       +++VTL+ +GHC GSVM   EG  G VLYTGDFR   + +  LS  + + GIK +K      LY+DTTF      H PSR     V + L+++ L  S    ++I   + Y  E L   I+   N  +H  D K     +  D +I++  DP   ++RIHAC                +KL  + P+T+W++   + S K      K S   RVC+S HSS+SEI +F+  ++ + ++
Sbjct:    1 MSTFCGRMREYSEISIDRFDGGNLLSSVFFLSHCHRDHMTGLNYRSFAKRLQAGNNIYLYMSDVSKVLLLGDNTYSFHHLEPYIKTLQIKRPSTITIPC--NTVSGKPKLVSVTLLPAGHCPGSVMFLFEGNEGTVLYTGDFRWEKDKAASLSHLHNELGIKPIK-----SLYIDTTFCVPNALHFPSRYQCVEVTVQLVKEWLSHSKSHFVYIASPMNYGHEHLQVEIFKHTNEPIHTSDWKYSIYTQIQDLAIAYTTDP---SARIHACV---------------SKLLVLRPSTMWFTMSTICSEKLKEEPTKSSDPHRVCYSLHSSYSEIKNFVSYLNPEEVF 322

[Close]

BLAST of DNA cross-link repair 1C vs. TrEMBL
Match: A0A2G8JWK7 (Lactamase_B domain-containing protein OS=Stichopus japonicus OX=307972 GN=BSL78_23048 PE=4 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 2.140e-39
Identity = 115/347 (33.14%), Postives = 184/347 (53.03%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNFNPL----VSTYFISHLHLDHLCGIENFS-ASHLT-----EIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDY-KYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVD---IKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS FSGI  EYP++AID F+         YF+SH+H DH  G+ + + A+HL      ++Y S+ T + +L  +S+ +++   +  L + +   + I    ND    K+ + VTL+ +GHC GSVM  +EG  G+VLYTGDFR  + ++  + + +   G+K +K      LY+DTTF +     IP+RE S   ++ +IE+ L      ++ I  + +Y  E L+  I   F +KVHV    +K Y ++  L E ++         +R+HA      CRK     K+   + TI P+T+W++  N   +  +  I     R+CFS HSS+SEI DFI  +   +IY
Sbjct:    1 MSTFSGITREYPEVAIDYFSGKQILKARAYFLSHVHTDHTVGLHSSTFANHLENHPTYKLYCSEVTREFLL-TSSKHRHLKKSLLALPVEQRCDVFIP---NDVTGEKEKLQVTLLPAGHCPGSVMFLLEGNAGKVLYTGDFRFKIGDAANMDALHDGEGVKALK-----SLYIDTTFFDPKIMFIPNREQSCEAMLRVIEEQLQRGPRHMVHIKCRAKYGYEYLFIEISRAFGMKVHVSGEIMKQYERVPSLAEHMTT----EGSATRVHA------CRKYACTLKDAVDVITITPSTMWFNS-NAQPDDVLKKISSHYYRLCFSFHSSYSEICDFIQYLKPTNIY 327

[Close]

BLAST of DNA cross-link repair 1C vs. TrEMBL
Match: A0A158NB18 (DRMBL domain-containing protein OS=Atta cephalotes OX=12957 GN=105617782 PE=4 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 1.076e-38
Identity = 118/358 (32.96%), Postives = 175/358 (48.88%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASHLTE----IYTSDSTAKLILGRNSE-FKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINY-------LDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVD---IKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHC--RKNFEEAKN--KNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCV 1049
            MS F G+I E P I++D F   N   S YF+SH H+DH+CG+ N    HL +    +Y S  T   +  +  E  +N+  YVK + + K   I I+Y  N      DI+ VT  S+GHC GSVM   E  N  +LYTGDFR+N         DY    KI  +NY        D +YLDTTF+     ++P+R +S  V+  +++K L ES   ++ ++    Y  E LY  +       +HV      SY ++  L   ++   +P   ++RIHAC   S C  R       N  +  + TI+P+   W  R+     E     + +  VC+S H+SF E+ +FI     K+I+ CV
Sbjct:    1 MSTFVGLIKEIPGISVDRFDRENMNSSVYFLSHCHIDHMCGLNNMFFDHLKQYNKYLYCSRITKVFLENKYYENLRNVETYVKDIEVDKK--ICIEYRSNYNSEETDILFVTFTSAGHCPGSVMFVFEKMNKLILYTGDFRIN-------PKDY---YKIKSLNYCNNFPKKFDNVYLDTTFLGHDFTYLPTRIESINVMCKVVKKWLDESPRKVVILECSALYGSEFLYMELSKSLKTLIHVKEYVYNSYIRIPELACHVT--NNP--LDARIHACMSKSTCMNRSGLRCRTNVLQQDILTIVPSVKKWKGRDTSVIGEWDKFSEKTFNVCYSTHASFDELKEFIQYFKPKNIHPCV 342

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Cavefish
Match: dclre1c (protein artemis [Source:NCBI gene;Acc:103039825])

HSP 1 Score: 129.028 bits (323), Expect = 2.419e-32
Identity = 112/356 (31.46%), Postives = 171/356 (48.03%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFSASH------LTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKL--------------FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F G + EY  I+ID F   N     YF+SH H DH+ G++              ++Y S  T +L+L  N ++     ++  L L     I +   D     S+D++ VTL+ +GHC GSVM   EG  G VLYTGDFRL + ++ ++   +  G ++  I     +YLD+TF +     IPSRE   + I  LI+  +  S   +++++ K  Y  E L+  +  +F+ +VHV+    Y+  P       C    N  ++IHAC    H +   EE    N+L               +I P+T+W+ ER     K +  +   S R CFS HSS+SEI DF+      +IY
Sbjct:    1 MSSFPGRMKEYSTISIDRFDKENLHARAYFLSHCHKDHMKGLKGPLLKRKLKFCLTVKLYCSFVTKELLLS-NRKYSFWEDHIVALELDSPTHISL--IDEVTGESEDVV-VTLLPAGHCPGSVMFLFEGAQGTVLYTGDFRLGIGDAARMEHLHS-GDRVKDIQ---SVYLDSTFYDPKFYQIPSREACLIGIRELIQDWISLSPYHVVWLNCKAAYGYEYLFTNLGEEFSSQVHVNSLDTYKKMPE----ILCHVTTNRATQIHACR---HPKD--EELFRTNRLPCGCTAPDGTPLRIVSIKPSTMWFGERTR-KTKVIVRMGGSSYRACFSFHSSYSEIKDFLSYTRPVNIY 338

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Cavefish
Match: dclre1b (DNA cross-link repair 1B [Source:NCBI gene;Acc:768137])

HSP 1 Score: 83.1889 bits (204), Expect = 4.793e-17
Identity = 86/317 (27.13%), Postives = 141/317 (44.48%), Query Frame = 3

Query:  108 VSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTL--EALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVS 1052
            V  +F+SH+H DH CG+ +  ++    IY S  TAKL+     + +    ++  L +G+++ + +    +D    K+ + VTLI + HC G+VM F EG  G +LYTGDFR       +          +     +D LYLD T  +   + +PSR+ +       I++I+    +  + I     Y L  E+L   + L+F   V VD +    L+ L+    F  +P     RI A         N      +     I+PT+     R +VS     Y+      V +S HSS+ E+ DF+  +   S+   V 
Sbjct:   24 VRLFFLSHMHTDHTCGLTSTWSNR--PIYCSPVTAKLL---QLKLQVKEKWIHALEVGEAHMLPL----DD--IGKEKLTVTLIDANHCPGAVMFFFEGYFGTILYTGDFRYTPSMLREPC--------LRNNTTIDVLYLDNTNCDPTRS-LPSRQRA----CQQIKEIIRSHPNYTVVIGL---YALGKESLLVQLALEFKTWVEVDTERLETLRVLELPDVFTTEP--GAGRIRAVSQSEITASNLLAWNKEQPTMAILPTS-----RPVVSCHPNVYV------VPYSDHSSYQELEDFVSALRPISLVPIVG 300

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Cavefish
Match: dclre1a (DNA cross-link repair 1A [Source:NCBI gene;Acc:103042754])

HSP 1 Score: 54.299 bits (129), Expect = 1.586e-7
Identity = 78/313 (24.92%), Postives = 133/313 (42.49%), Query Frame = 3

Query:  108 VSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGR-VLYTGDFRLN--LENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLI-EKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLD-ESISFCVDPCNWNSRIHACYMDSHCRKNFEE-----AKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSV-RVCFSHHSSFSEIIDFI 1013
            ++ YF++H H DH  G+   S      IY +  T  L+    S+ K    YV  L +     +             D + VTL+ + HC G+ ML     +G+ VL+TGDFR +  +E   +L      G ++        LYLDTT+ +   A  P++++      N   E + L     ++   Y V    E ++  I      KV++    Y  +  L+ + I  C+      +R+H   M     KN E      +++ ++L    PT   ++    V+N +    +  S+  V +S HSSF E+  F+
Sbjct:  620 ITAYFLTHFHSDHYGGLTKRST---LPIYCNKITGNLV---KSKLKVDEQYVHILPMNTECVV-------------DGVKVTLLDANHCPGAAMLLFLLPDGQTVLHTGDFRADPSMERYPEL-----QGFRVQT------LYLDTTYCSPEYA-FPTQQEVITFAANTAFELVTLNPRTLVVCGTYAVGK--EKVFLAISDVLASKVYMSRDRYNTMCCLESKQICQCITTDPKAARVHVLPMMQLNFKNLEAHLHKHSQSYDQLVAFKPTGWTFTHSGDVTNIQPEVKNNISIYGVPYSEHSSFLELKRFV 899

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BLAST of DNA cross-link repair 1C vs. Ensembl Sea Lamprey
Match: dclre1c (DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) [Source:NCBI gene;Acc:566285])

HSP 1 Score: 164.851 bits (416), Expect = 3.540e-47
Identity = 115/355 (32.39%), Postives = 183/355 (51.55%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGI------ENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKP--LDESISFCVDPCNWNSRIHACYMDSH----------CRKNFEEAKNKN-KLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F G   EYP ++ID F   N     +F+SH H DH+ G+      +    S    +Y S  T +L+L  N  ++ +  +   + +    + +I  +D+      D++ VTL+ +GHC GSVM   EG +G VLYTGDFRL     +++ + +  G    +I  +  +YLDTTF +  C +IPSRED    I+NL+   + +S   +I+++ K  Y  E L+  +  +F  KVH+     +Q  P  LD          + N++IHAC +             CR+  ++AK K+  + +I P+T+W+++RN    K +    + S R CFS HSSFSEI DFI  +   +I+
Sbjct:    1 MSSFLGKTAEYPSVSIDRFDRDNVDARAFFLSHCHQDHMVGLYSEALRKKLERSPGVHLYCSPVTRELLLS-NWRYRFLERFT--VAIEVDTATQISLTDDKTKQKTDLV-VTLLPAGHCPGSVMFLFEGDHGAVLYTGDFRLPRGGVSRMGALHSAG----RIKRIKSIYLDTTFCDPMCYYIPSREDCLKGILNLVRGWITQSPQHVIWLNCKAAYGYEYLFTHLSREFGQKVHLGYLEMFQNMPDILDHVTH------DSNTQIHACRIPKDAGICEGRRLPCRE--KDAKGKSLHMMSIKPSTMWFTQRN-KKTKIIVRTGESSYRACFSFHSSFSEIEDFISYIKPANIF 338

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BLAST of DNA cross-link repair 1C vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006050.1 (pep scaffold:Pmarinus_7.0:GL476493:567169:571241:-1 gene:ENSPMAG00000005467.1 transcript:ENSPMAT00000006050.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.337 bits (194), Expect = 9.521e-17
Identity = 58/185 (31.35%), Postives = 92/185 (49.73%), Query Frame = 3

Query:   51 FSGIIYEYPQIAIDNFN----PLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKIN-YLDGLYLDTTFMNKCCA--HIPSREDS 584
             +G +  Y  +A+D +     P    +F+SH+H DH  G+   + +    IY S  TA L+     +F     +++PL LG+S+ + +          K+ + VTLI + HC G+VM   +G  G +LYTGDFR   E            + +++ N  +D LYLD T+   C +  H PSRED+
Sbjct:    1 MNGKLIPYTPLAVDFWRVAKFPEARIFFLSHMHADHTSGL---TPTWSRPIYCSPITAVLL---KRKFSIADKFIRPLELGESHCVPL------DGVGKETMTVTLIDANHCPGAVMFLFQGYFGNILYTGDFRFIPE---------MLKLPLLQTNIIIDVLYLDNTY---CPSKWHFPSREDA 161

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BLAST of DNA cross-link repair 1C vs. Ensembl Yeast
Match: PSO2 (Nuclease required for DNA single- and double-strand break repair; acts at a post-incision step in repair of breaks that result from interstrand cross-links produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004745])

HSP 1 Score: 51.6026 bits (122), Expect = 1.248e-7
Identity = 50/173 (28.90%), Postives = 83/173 (47.98%), Query Frame = 3

Query:   78 QIAIDNFN----PLVSTYFISHLHLDHLCGIE----NFSASHLTE-IYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGS-VMLFIE-------GKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFM 545
            +I +D FN      +S YF+SH H DH  G++    N   + + + +Y S  TA L+   N +FK  +  ++ L + K + I             D I+V  + + HC G+ +MLF E           ++L+TGDFR    N+  + +  K+  +      +D +YLDTT+M
Sbjct:  227 EIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSWNNPDENPIKKTLYCSKITAILV---NLKFKIPMDEIQILPMNKRFWI------------TDTISVVTLDANHCPGAIIMLFQEFLANSYDKPIRQILHTGDFR---SNAKMIETIQKWLAETAN-ETIDQVYLDTTYM 380

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BLAST of DNA cross-link repair 1C vs. Ensembl Nematostella
Match: EDO48182 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK35])

HSP 1 Score: 128.257 bits (321), Expect = 1.906e-34
Identity = 91/305 (29.84%), Postives = 159/305 (52.13%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIENFS-----ASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESIS-FCVDPCNWNSRIHACYM---DSHCRKNFEEAKN--KNKLFTIIPTTLWWSER 914
            MS F G + EYPQ++ID F   N     YF+SH H DH+ G+++ +      S    I+ S++T  L+L  ++ F ++  Y+  + L + + +     + ++   +++I VTL S+GHC+GSVM   EG  G VLYTGDFRL   ++ +++  +  G    ++  +  +Y+DTTF       IPSR+++   I  +I++   +  + ++ +  K +Y  E +   I + + IK+HV  +     + L + I  F  D     +RIHAC+    DS          N  + K+  I P+T W+++R
Sbjct:    1 MSCFRGKLLEYPQVSIDCFDNENLDSYAYFLSHCHRDHMQGLDSATFSDAIKSKKQRIFCSETTRNLLLC-DASFSHLEEYLTGIPLDQPFVVTPYDKETNK---EEVITVTLFSAGHCVGSVMFLFEGLKGNVLYTGDFRLATGDTKRITVLHCNG----RVKDIRSVYIDTTFCLPKMMSIPSRKETNDAIFKVIDRWFSQGAEHVVSLQCKSKYGYEYMLKSIAIYYKIKIHVSDERLEMYRYLSDMIQHFTTDAS--KTRIHACHWKNSDSSTLPCGLVLPNGLEPKVLRIRPSTFWFAQR 295

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BLAST of DNA cross-link repair 1C vs. Ensembl Nematostella
Match: EDO46457 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPX0])

HSP 1 Score: 83.5741 bits (205), Expect = 3.665e-18
Identity = 82/310 (26.45%), Postives = 139/310 (44.84%), Query Frame = 3

Query:  117 YFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGR---NSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSI 1037
            +F+SH H DH  G+ +    +  +IY S+ T ++++ +   N +    +P  +P+ L                  ++++ VTL+ + HC G+VM   EG  G +LYTGDFR         S         +K   +D LYLD T+ +  C + P++  +  +I ++I + L +  D II +    +   E L   I L+FN  + V  K    LK LD    F  +       +    ++S+    F +       F I+PT L+  E+   SN   H  +   V V +S HSSF E++ F+  +    +
Sbjct:   27 FFLSHAHADHTQGLTSSWTKY--KIYCSEITKRILMHKLNVNEDLLVALPLGEPVVLPLDEE------------GREMLTVTLLDANHCPGAVMFLFEGYFGTILYTGDFRFKPAMLLHES---------LKGKQIDKLYLDNTYCHPSC-NFPTKTKTMKLIFDIIRRRLGD--DIIIPLRTLGK---EDLLVKIALEFNCWIGVTPKKMELLKWLDLPDVFTSEWHKTQIIVAQHPVNSYTLSQFRDP------FVILPTALYEGEK---SNPYRHLPN--YVTVPYSDHSSFKELLRFVSGIAPAEV 296

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BLAST of DNA cross-link repair 1C vs. Ensembl Nematostella
Match: EDO43089 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZG8])

HSP 1 Score: 71.633 bits (174), Expect = 4.956e-14
Identity = 82/313 (26.20%), Postives = 128/313 (40.89%), Query Frame = 3

Query:  102 PLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGR-VLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTL--EALYHLIYLKFNIKVHVDIKSYYQLKPLDES-ISFCVDPCNWNSRIHACYMD----SHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSV-RVCFSHHSSFSEIIDFI 1013
            P +  YF+SH H DH  G++    SH   IY S  TA L+    S+ K    Y+K L +             D     D + VTL+ + HC G+V+L  E  NG+ +L+TGDFR + E  +  +         +    +D LYLDTT+ +      P +E++    +    + + E+  T+I       YT+  E ++  I  +   KV V       L  L+   I   +       RIH   M      H     ++ K K         T W  +   +S          S+  V +S HSS+ E+  F+
Sbjct:   24 PGIKVYFLSHFHYDHYGGLKK-GFSH--PIYCSKVTANLV---ESKIKVSQRYIKALPM-------------DTPVIVDKVQVTLLDANHCPGAVLLLFELPNGKTILHTGDFRASREMESYPA---------LANKTIDTLYLDTTYCDPQYT-FPKQEETINFAVTKAAQAVSENPKTLIVCG---TYTIGKEKVFLAIAKELGCKVTVQSDKKRILDSLESDFIQSVITTDKSEGRIHVLPMGKLNHQHLSSYMDQFKGKFTRVVAFKPTGWEHKSGPLSATRPVTKGPISIYGVPYSEHSSYEEMKRFV 304

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BLAST of DNA cross-link repair 1C vs. Ensembl Medaka
Match: dclre1c (DNA cross-link repair 1C [Source:NCBI gene;Acc:101169653])

HSP 1 Score: 137.117 bits (344), Expect = 2.345e-35
Identity = 109/356 (30.62%), Postives = 175/356 (49.16%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIEN------FSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKL--------------FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F+G + EYP +++D F   N     YF+SH H DH+ G++          S    +Y S  T +L+L  N ++     Y+ PL L     I +    ++    K+ + VTL+ +GHC GSVM   EG  G VLYTGDFRL + +  ++   +  G ++  I     +Y+D+TF +     IPSRE     I  L+   + +S   +++++ K  Y  E L+  +  +F  ++HV+  S    K + E +S+     + ++RIHAC    H +   EE    N+L               +I P+T+W+ ER   +N  +      S R CFS HSS+SE+ DF+  +   +IY
Sbjct:    1 MSSFAGRMKEYPTVSLDRFDRENLHARAYFLSHCHKDHMKGLKGPLLKRKLQFSRTVRLYCSFVTKELLL-NNQKYSFWEEYIVPLELESPTQISLV---DEASGEKEEVVVTLLPAGHCPGSVMFLFEGCRGNVLYTGDFRLAVGDVARMELLHS-GSRVKDIQ---SVYVDSTFYDPRFYQIPSREVCLKGISELVGNWISQSPYHVVWLNCKAAYGYEYLFTNLGEEFGTQIHVN--SLAMFKKMPEILSYVT--TDRSARIHACR---HPKD--EEFFQGNRLPCGCSAADGTPLRIISIKPSTMWFGERTKRTNVIIR-TGSSSYRACFSFHSSYSELKDFLAYLKPVNIY 338

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BLAST of DNA cross-link repair 1C vs. Ensembl Medaka
Match: dclre1c (DNA cross-link repair 1C [Source:NCBI gene;Acc:101169653])

HSP 1 Score: 124.02 bits (310), Expect = 8.268e-31
Identity = 104/356 (29.21%), Postives = 166/356 (46.63%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNF---NPLVSTYFISHLHLDHLCGIEN------FSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKL--------------FTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIY 1040
            MS F+G + EYP +++D F   N     YF+SH H DH+ G++          S    +Y S  T +L+L  N ++     Y+ PL L     I +    ++    K+ + VTL+ +GHC GSVM   EG  G VLYTGDFRL + +           +  M++ +     +D    N      P RE     I  L+   + +S   +++++ K  Y  E L+  +  +F  ++HV+  S    K + E +S+     + ++RIHAC    H +   EE    N+L               +I P+T+W+ ER   +N  +      S R CFS HSS+SE+ DF+  +   +IY
Sbjct:    1 MSSFAGRMKEYPTVSLDRFDRENLHARAYFLSHCHKDHMKGLKGPLLKRKLQFSRTVRLYCSFVTKELLL-NNQKYSFWEEYIVPLELESPTQISLV---DEASGEKEEVVVTLLPAGHCPGSVMFLFEGCRGNVLYTGDFRLAVGD-----------VARMELLHSGSRSVDALQQN------PDREVCLKGISELVGNWISQSPYHVVWLNCKAAYGYEYLFTNLGEEFGTQIHVN--SLAMFKKMPEILSYVT--TDRSARIHACR---HPKD--EEFFQGNRLPCGCSAADGTPLRIISIKPSTMWFGERTKRTNVIIR-TGSSSYRACFSFHSSYSELKDFLAYLKPVNIY 325

[Close]

BLAST of DNA cross-link repair 1C vs. Ensembl Medaka
Match: dclre1b (DNA cross-link repair 1B [Source:NCBI gene;Acc:101166551])

HSP 1 Score: 73.559 bits (179), Expect = 8.278e-14
Identity = 88/335 (26.27%), Postives = 144/335 (42.99%), Query Frame = 3

Query:   57 GIIYEYPQIAIDNFN----PLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKIN-YLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTL--EALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVS-NKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSI 1037
            G I  +  +A+D ++    P    +F+SH+H DH  G+ +  +     IY S  TAKL+  +    +    ++ PL +G+   + +          K+ + VTLI + HC G+VM   +G  G +LYTGDFR          S        +K N  +D LYLD T  +     +PSR+ +       I++I+    D  + I     YTL  E+L   +  +F   V V       LK L+    F  +      R            + ++  N+     I+PT+     R L+S +  VH        V +S HSS+ E++DF+  +   S+
Sbjct:    5 GKIIPHTPLAVDFWHVRKCPSARLFFLSHMHADHTVGLTSTWSGR--PIYCSPVTAKLLHLKLKVKEQ---WIHPLEIGEQNLLPL------DDIGKETLTVTLIDANHCPGAVMFLFQGYFGSILYTGDFRY---------SPSMLREPCLKNNITIDVLYLDDTNCDPNRT-LPSRQKA----TQQIKEIIRSHPDHNVVIGL---YTLGKESLLLELAKEFQTWVEVSYDRMETLKVLELPDVFTTE--QGTGRFRVVDHSEITSASLQDWNNEQPTLAILPTS-----RPLISYHPSVHV-------VPYSDHSSYQEVVDFVSTLKPMSL 297

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BLAST of DNA cross-link repair 1C vs. Planmine SMEST
Match: SMESG000028344.1 (SMESG000028344.1)

HSP 1 Score: 660.603 bits (1703), Expect = 0.000e+0
Identity = 329/345 (95.36%), Postives = 329/345 (95.36%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 1076
            MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASH TEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT               DYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK
Sbjct:    1 MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHQTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT---------------DYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 330

[Close]

BLAST of DNA cross-link repair 1C vs. Planmine SMEST
Match: SMESG000028344.1 (SMESG000028344.1)

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 327/343 (95.34%), Postives = 327/343 (95.34%), Query Frame = 3

Query:   48 MFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 1076
            MFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASH TEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT               DYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK
Sbjct:    1 MFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHQTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT---------------DYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 328

[Close]

BLAST of DNA cross-link repair 1C vs. Planmine SMEST
Match: SMESG000028344.1 (SMESG000028344.1)

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 322/345 (93.33%), Postives = 322/345 (93.33%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 1076
            MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASH TEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT               DYK       INYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK
Sbjct:    1 MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHQTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT---------------DYK-------INYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 323

[Close]

BLAST of DNA cross-link repair 1C vs. Planmine SMEST
Match: SMESG000028344.1 (SMESG000028344.1)

HSP 1 Score: 635.565 bits (1638), Expect = 0.000e+0
Identity = 320/343 (93.29%), Postives = 320/343 (93.29%), Query Frame = 3

Query:   48 MFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 1076
            MFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASH TEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT               DYK       INYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK
Sbjct:    1 MFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHQTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT---------------DYK-------INYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVHYIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK 321

[Close]

BLAST of DNA cross-link repair 1C vs. Planmine SMEST
Match: SMESG000028344.1 (SMESG000028344.1)

HSP 1 Score: 468.389 bits (1204), Expect = 7.998e-168
Identity = 238/261 (91.19%), Postives = 238/261 (91.19%), Query Frame = 3

Query:   42 MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHLTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGIKIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM 824
            MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASH TEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT               DY       KINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM
Sbjct:    1 MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHQTEIYTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDIINVTLISSGHCLGSVMLFIEGKNGRVLYT---------------DY-------KINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTIIFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPCNWNSRIHACYM 239

The following BLAST results are available for this feature:

BLAST of DNA cross-link repair 1C vs. Ensembl Human
BLAST of DNA cross-link repair 1C vs. Ensembl Celegans
BLAST of DNA cross-link repair 1C vs. Ensembl Fly
BLAST of DNA cross-link repair 1C vs. Ensembl Zebrafish
BLAST of DNA cross-link repair 1C vs. Ensembl Xenopus
BLAST of DNA cross-link repair 1C vs. Ensembl Mouse
BLAST of DNA cross-link repair 1C vs. UniProt/SwissProt
BLAST of DNA cross-link repair 1C vs. TrEMBL
BLAST of DNA cross-link repair 1C vs. Ensembl Cavefish
BLAST of DNA cross-link repair 1C vs. Ensembl Sea Lamprey
BLAST of DNA cross-link repair 1C vs. Ensembl Yeast
BLAST of DNA cross-link repair 1C vs. Ensembl Nematostella
BLAST of DNA cross-link repair 1C vs. Ensembl Medaka
BLAST of DNA cross-link repair 1C vs. Planmine SMEST

BLAST of DNA cross-link repair 1C vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DCLRE1C	1.342e-36	30.52	DNA cross-link repair 1C [Source:HGNC Symbol;Acc:H...	[more]
DCLRE1C	3.248e-35	30.52	DNA cross-link repair 1C [Source:HGNC Symbol;Acc:H...	[more]
DCLRE1C	5.177e-20	29.68	DNA cross-link repair 1C [Source:HGNC Symbol;Acc:H...	[more]
DCLRE1C	5.177e-20	29.68	DNA cross-link repair 1C [Source:HGNC Symbol;Acc:H...	[more]
DCLRE1C	5.177e-20	29.68	DNA cross-link repair 1C [Source:HGNC Symbol;Acc:H...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
mrt-1	4.284e-11	26.35	MoRTal germline [Source:UniProtKB/TrEMBL;Acc:Q8T3...	[more]
mrt-1	4.284e-11	26.35	MoRTal germline [Source:UniProtKB/TrEMBL;Acc:Q8T3...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Snm1	4.330e-8	30.20	gene:FBgn0037338 transcript:FBtr0078688	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dclre1c	2.750e-36	30.90	DNA cross-link repair 1C, PSO2 homolog (S. cerevis...	[more]
dclre1c	2.750e-36	30.90	DNA cross-link repair 1C, PSO2 homolog (S. cerevis...	[more]
dclre1c	3.104e-28	28.37	DNA cross-link repair 1C, PSO2 homolog (S. cerevis...	[more]
dclre1b	5.708e-15	27.10	DNA cross-link repair 1B [Source:NCBI gene;Acc:768...	[more]
dclre1b	5.708e-15	27.10	DNA cross-link repair 1B [Source:NCBI gene;Acc:768...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DCLRE1C	3.294e-34	30.23	DNA cross-link repair 1C [Source:NCBI gene;Acc:100...	[more]
DCLRE1C	1.455e-33	30.23	DNA cross-link repair 1C [Source:NCBI gene;Acc:100...	[more]
DCLRE1C	1.752e-33	30.06	DNA cross-link repair 1C [Source:NCBI gene;Acc:100...	[more]
DCLRE1C	1.840e-33	30.23	DNA cross-link repair 1C [Source:NCBI gene;Acc:100...	[more]
DCLRE1C	3.349e-32	29.95	DNA cross-link repair 1C [Source:NCBI gene;Acc:100...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dclre1c	3.071e-38	31.88	DNA cross-link repair 1C [Source:MGI Symbol;Acc:MG...	[more]
Dclre1c	1.180e-37	31.88	DNA cross-link repair 1C [Source:MGI Symbol;Acc:MG...	[more]
Dclre1c	4.854e-37	31.88	DNA cross-link repair 1C [Source:MGI Symbol;Acc:MG...	[more]
Dclre1b	7.911e-16	25.37	DNA cross-link repair 1B [Source:MGI Symbol;Acc:MG...	[more]
Dclre1b	7.911e-16	25.37	DNA cross-link repair 1B [Source:MGI Symbol;Acc:MG...	[more]

BLAST of DNA cross-link repair 1C vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8K4J0\|DCR1C_MOUSE	3.395e-36	31.88	Protein artemis OS=Mus musculus OX=10090 GN=Dclre1...	[more]
sp\|Q5QJC2\|DCR1C_CHICK	1.269e-35	31.91	Protein artemis OS=Gallus gallus OX=9031 GN=DCLRE1...	[more]
sp\|Q5RGE5\|DCR1C_DANRE	2.076e-35	30.90	Protein artemis OS=Danio rerio OX=7955 GN=dclre1c ...	[more]
sp\|Q5XIX3\|DCR1C_RAT	5.531e-35	31.61	Protein artemis OS=Rattus norvegicus OX=10116 GN=D...	[more]
sp\|Q5R6Z9\|DCR1C_PONAB	7.569e-35	31.10	Protein artemis OS=Pongo abelii OX=9601 GN=DCLRE1C...	[more]

BLAST of DNA cross-link repair 1C vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
C3YPJ3	1.573e-43	31.59	DRMBL domain-containing protein OS=Branchiostoma f...	[more]
S4RFM2	4.608e-43	32.39	DNA cross-link repair 1C, PSO2 homolog (S. cerevis...	[more]
V4A3J4	2.753e-40	33.14	DRMBL domain-containing protein OS=Lottia gigantea...	[more]
A0A2G8JWK7	2.140e-39	33.14	Lactamase_B domain-containing protein OS=Stichopus...	[more]
A0A158NB18	1.076e-38	32.96	DRMBL domain-containing protein OS=Atta cephalotes...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
dclre1c	2.419e-32	31.46	protein artemis [Source:NCBI gene;Acc:103039825]	[more]
dclre1b	4.793e-17	27.13	DNA cross-link repair 1B [Source:NCBI gene;Acc:768...	[more]
dclre1a	1.586e-7	24.92	DNA cross-link repair 1A [Source:NCBI gene;Acc:103...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
dclre1c	3.540e-47	32.39	DNA cross-link repair 1C, PSO2 homolog (S. cerevis...	[more]
ENSPMAT00000006050.1	9.521e-17	31.35	pep scaffold:Pmarinus_7.0:GL476493:567169:571241:-...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
PSO2	1.248e-7	28.90	Nuclease required for DNA single- and double-stran...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO48182	1.906e-34	29.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46457	3.665e-18	26.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43089	4.956e-14	26.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of DNA cross-link repair 1C vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
dclre1c	2.345e-35	30.62	DNA cross-link repair 1C [Source:NCBI gene;Acc:101...	[more]
dclre1c	8.268e-31	29.21	DNA cross-link repair 1C [Source:NCBI gene;Acc:101...	[more]
dclre1b	8.278e-14	26.27	DNA cross-link repair 1B [Source:NCBI gene;Acc:101...	[more]

BLAST of DNA cross-link repair 1C vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000028344.1	0.000e+0	95.36	SMESG000028344.1	[more]
SMESG000028344.1	0.000e+0	95.34	SMESG000028344.1	[more]
SMESG000028344.1	0.000e+0	93.33	SMESG000028344.1	[more]
SMESG000028344.1	0.000e+0	93.29	SMESG000028344.1	[more]
SMESG000028344.1	7.998e-168	91.19	SMESG000028344.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30015874 ID=SMED30015874|Name=DNA cross-link repair 1C|organism=Schmidtea mediterranea sexual|type=transcript|length=1109bp
GGATTCACTTGTTTTTTTAATATTTTTTTAAACATGGAATAATGTCAATG
TTTTCTGGAATTATTTATGAATATCCACAAATTGCCATAGATAATTTTAA
TCCTTTAGTTTCGACTTATTTTATTTCACACTTGCATTTAGATCATTTAT
GTGGAATTGAAAATTTTTCGGCTTCTCATCTAACTGAAATTTATACTTCT
GATTCCACAGCCAAATTAATATTAGGACGTAATTCTGAATTTAAAAACAT
TGTTCCATATGTTAAACCTTTATGTTTGGGAAAATCATATTCTATTAAAA
TAAAATATTCGGATAATGATCAATACTTTTCTAAAGATATTATTAATGTC
ACGCTAATCTCTTCAGGACATTGTTTAGGTTCAGTGATGCTCTTCATTGA
AGGGAAAAATGGTCGAGTACTATATACCGGTGACTTTCGTTTAAATTTAG
AAAATTCGAATCAATTATCTTCAGATTACAAGTATGGTATAAAAATAATG
AAAATTAATTACTTGGATGGTTTATATTTGGATACAACTTTTATGAACAA
ATGTTGTGCACATATTCCTTCTCGAGAAGATAGTTTTGTGGTAATTATTA
ATCTAATTGAGAAAATTTTGCTGGAAAGTTTGGACACTATAATCTTTATT
GATTATAAAGTCAGATACACTTTAGAAGCTTTATATCACCTTATTTACTT
GAAGTTTAACATAAAGGTTCATGTTGATATCAAATCGTATTATCAACTCA
AGCCTTTGGATGAAAGTATTTCATTTTGTGTTGACCCATGTAATTGGAAT
TCTCGCATACATGCTTGCTATATGGATAGTCACTGCAGAAAAAATTTTGA
AGAAGCTAAAAATAAAAATAAGTTATTTACAATAATTCCTACTACATTAT
GGTGGTCAGAAAGAAATTTAGTTAGTAACAAGGAAGTCCATTATATTGAT
AAATTTTCTGTTCGAGTGTGTTTTTCACACCATAGTTCATTTTCGGAAAT
CATAGATTTTATTTTAAAAGTTCATTCGAAAAGTATTTACTACTGTGTTT
CACAAACTTGTAATACGCTAAAAAAGTAATTCTTAAAAAGTCTTAATTTT
TGTTTTAAT

protein sequence of SMED30015874-orf-1

>SMED30015874-orf-1 ID=SMED30015874-orf-1|Name=SMED30015874-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=346bp
MSMFSGIIYEYPQIAIDNFNPLVSTYFISHLHLDHLCGIENFSASHLTEI
YTSDSTAKLILGRNSEFKNIVPYVKPLCLGKSYSIKIKYSDNDQYFSKDI
INVTLISSGHCLGSVMLFIEGKNGRVLYTGDFRLNLENSNQLSSDYKYGI
KIMKINYLDGLYLDTTFMNKCCAHIPSREDSFVVIINLIEKILLESLDTI
IFIDYKVRYTLEALYHLIYLKFNIKVHVDIKSYYQLKPLDESISFCVDPC
NWNSRIHACYMDSHCRKNFEEAKNKNKLFTIIPTTLWWSERNLVSNKEVH
YIDKFSVRVCFSHHSSFSEIIDFILKVHSKSIYYCVSQTCNTLKK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0000014	single-stranded DNA endodeoxyribonuclease activity
GO:0008409	5'-3' exonuclease activity
GO:0003684	damaged DNA binding
GO:0004518	nuclease activity
GO:0004519	endonuclease activity
GO:0004527	exonuclease activity
GO:0016787	hydrolase activity
GO:0035312	5'-3' exodeoxyribonuclease activity

Vocabulary: **biological process**
Term	Definition
GO:0000723	telomere maintenance
GO:0006302	double-strand break repair
GO:0010212	response to ionizing radiation
GO:0030183	B cell differentiation
GO:0033151	V(D)J recombination
GO:0051276	chromosome organization
GO:0002250	adaptive immune response
GO:0002376	immune system process
GO:0006281	DNA repair
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0006310	DNA recombination
GO:0006974	cellular response to DNA damage stimulus
GO:0031848	protection from non-homologous end joining at telomere
GO:0036297	interstrand cross-link repair
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Vocabulary: **cellular component**
Term	Definition
GO:0005654	nucleoplasm
GO:0005794	Golgi apparatus
GO:0000784	nuclear chromosome, telomeric region
GO:0005634	nucleus
GO:0070419	nonhomologous end joining complex

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000017	photoreceptor neuron
PLANA:0000418	head
PLANA:0002075	pigment cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036866	RibonucZ/Hydroxyglut_hydro
IPR011084	DRMBL
IPR001279	Metallo-B-lactamas

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR011084	DNA repair metallo-beta-lactamase	PFAM	PF07522	DRMBL	coord: 254..336 e-value: 3.9E-8 score: 33.5
IPR001279	Metallo-beta-lactamase	PFAM	PF00753	Lactamase_B	coord: 27..137 e-value: 1.0E-4 score: 22.4
IPR036866	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like	GENE3D	G3DSA:3.60.15.10		coord: 11..336 e-value: 1.5E-53 score: 184.1
IPR036866	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like	SUPERFAMILY	SSF56281	Metallo-hydrolase/oxidoreductase	coord: 23..325
None	No IPR available	GENE3D	G3DSA:3.40.50.12650		coord: 174..314 e-value: 1.5E-53 score: 184.1
None	No IPR available	PANTHER	PTHR23240:SF8	PROTEIN ARTEMIS	coord: 2..336
None	No IPR available	PANTHER	PTHR23240	DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED	coord: 2..336