Glycine receptor subunit alpha-3
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015710 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 242.662 bits (618), Expect = 2.076e-73 Identity = 144/449 (32.07%), Postives = 228/449 (50.78%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQH 1524
LDK++ Y + RP+ + V I I + SV M Y +++LRQ W DSRL + + +S + PS+ D IW PDLFF N K H++TT N L+R+ NG+VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ +E ++ S + + G A P+P P + + K+ +R K ID SR FP FL++N FYW+ Y + IR+ H
Sbjct: 47 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRES-------RFNFSGYGMGHCLQVKDGTAVKATPANPLP-----------QPPKDGDAIKKKFVDRAK--------------------RIDTISRAAFPLAFLIFNIFYWITYKI-IRHEDVH 450
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 239.58 bits (610), Expect = 2.510e-73 Identity = 133/406 (32.76%), Postives = 211/406 (51.97%), Query Frame = 1
Query: 307 MQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQH 1524
M Y +++LRQ W DSRL + + +S + PS+ D IW PDLFF N K H++TT N L+R+ NG+VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ +E ++ S + + G A P+P P + + K+ +R K ID SR FP FL++N FYW+ Y + IR+ H
Sbjct: 1 MDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRES-------RFNFSGYGMGHCLQVKDGTAVKATPANPLP-----------QPPKDGDAIKKKFVDRAK--------------------RIDTISRAAFPLAFLIFNIFYWITYKI-IRHEDVH 361
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 241.891 bits (616), Expect = 3.269e-73 Identity = 143/449 (31.85%), Postives = 228/449 (50.78%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQH 1524
LDK++ Y + RP+ + V I I + S+ M Y +++LRQ W DSRL + + +S + PS+ D IW PDLFF N K H++TT N L+R+ NG+VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ +E ++ S + + G A P+P P + + K+ +R K ID SR FP FL++N FYW+ Y + IR+ H
Sbjct: 47 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRES-------RFNFSGYGMGHCLQVKDGTAVKATPANPLP-----------QPPKDGDAIKKKFVDRAK--------------------RIDTISRAAFPLAFLIFNIFYWITYKI-IRHEDVH 450
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRB (glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329]) HSP 1 Score: 241.121 bits (614), Expect = 2.128e-72 Identity = 150/474 (31.65%), Postives = 255/474 (53.80%), Query Frame = 1
Query: 148 DISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD-TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVL---------KRNTSKSWQSDVCSLIREEINL-------MHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSS------VDSTIDNYSRFLFPACFLLYNCFYWLYYI 1497
D++ ++ I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD + IE +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + ++++ LP+VSY+KA+DVWLIAC++F A+LVE+A+ +L K +K+ Q+D + N +H S + ++ SN I+G+ LP ++ S + K ++ N + + K NN K + ID Y+R LFP CFL +N YW Y+
Sbjct: 47 DLARVPANSTSNILNRLL--VSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLP--SDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGS---------LPRDFEL------SNYDCYGKPIEVNNGLGKSQAK--NNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRB (glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329]) HSP 1 Score: 241.121 bits (614), Expect = 2.128e-72 Identity = 150/474 (31.65%), Postives = 255/474 (53.80%), Query Frame = 1
Query: 148 DISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD-TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVL---------KRNTSKSWQSDVCSLIREEINL-------MHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSS------VDSTIDNYSRFLFPACFLLYNCFYWLYYI 1497
D++ ++ I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD + IE +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + ++++ LP+VSY+KA+DVWLIAC++F A+LVE+A+ +L K +K+ Q+D + N +H S + ++ SN I+G+ LP ++ S + K ++ N + + K NN K + ID Y+R LFP CFL +N YW Y+
Sbjct: 47 DLARVPANSTSNILNRLL--VSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLP--SDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGS---------LPRDFEL------SNYDCYGKPIEVNNGLGKSQAK--NNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-3 (Glutamate-gated ChLoride channel; Glutamate-gated chloride channel subunit [Source:UniProtKB/TrEMBL;Acc:G5EEZ3]) HSP 1 Score: 233.417 bits (594), Expect = 5.217e-70 Identity = 152/482 (31.54%), Postives = 253/482 (52.49%), Query Frame = 1
Query: 145 CDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL------VMIYIKIL--AIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELK--IPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIAT-----SVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGA-------TGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFT-------MKKPNNTKSKSSVDST---IDNYSRFLFPACFLLYNCFYWLYY 1494
CD SS I KLL K Y + RP N T+ V++Y+ +L +I +D M+YS + R+ W+D RL + + + + + +IW+PD FF+N K+ + H++ PN L+R+ +G +LYS +++MV SC M LQ +PMD Q C I++ SY YT ++++ W+ D + ++K L +P F+ ++ T+ CT S T+TG Y+CL+ ++ L RQ YL Y+PS ++++VSW++FW+ AVPAR+TLG+ +LL + A +++ LP VSY KAIDVW+ AC+ F+ AL+EFA T S KRN + S ++ + ++ + + +T + + +G+ A +G K + + I+ NN E+++ D ++K RF ++ +++ +VD D SR LFP F+ +N YW Y
Sbjct: 22 CDASS-----DTEIIKKLLGK-GYDWRVRPPGINLTIPGTHGAVIVYVNMLIRSISKIDDVNMEYSVQLTFREEWVDGRLAYGFPGD---STPDFLILTAGQQIWMPDSFFQNEKQAHKHDIDKPNVLIRIHRDGRILYSVRISMVLSCPMHLQYYPMDVQTCLIDLASYAYTENDIEYRWKKTDPVQLKKGLHSSLPSFELNNVDTTL-CT--SKTNTGTYSCLRTVLELRRQFSYYLLQLYIPSTMLVIVSWVSFWLDRGAVPARVTLGVTTLLTMTTQASGINAKLPPVSYTKAIDVWIGACLTFIFGALLEFAWVTYISSRSFYKRNKNCSSRNSLLIETKQALIIPNT-----------VVAQFPEHPEEVEMGLAQAPDVWIRQSGNGKTVSRVNGHIN---HNNDEAAELII--FDAKHKNRRFVWWTNFRNIRLIRWIRNRLNVDDNAKRADLISRVLFPTLFVCFNFVYWTKY 475
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-14 (pep chromosome:WBcel235:I:5967250:5973320:-1 gene:WBGene00000232.1 transcript:B0207.12b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-14) HSP 1 Score: 227.254 bits (578), Expect = 2.716e-68 Identity = 115/314 (36.62%), Postives = 182/314 (57.96%), Query Frame = 1
Query: 232 PDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSL----------KDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELK--IPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIAT-----SVLKRNTSKSWQSDVC 1122
PD LV + I + +I +D M+YS R+ W D RL +E EE V P + +IW+PD FF+N K+ H + PN L+R+ NG++LYS +L++V SC M L+ +P+D QNC I++ SY YT +++K+ W+ I + L+ +P F+ D++ T CT S T+TG Y+C + ++ L R+ YL Y+P I++++VSW++FW+ DAVPAR++LG+ +LL + A ++S LP VSYIKA+DVW+ C+ F+ AL+E+A+ L++ K + D C
Sbjct: 52 PDTGGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAYERYEE---SGDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLRQSLPSFELQDVV-TDYCT--SLTNTGEYSCARVVLRLRREYSYYLIQLYIPCIMLVVVSWVSFWLDKDAVPARVSLGVTTLLTMTTQASGINSKLPPVSYIKAVDVWIGVCLAFIFGALLEYAVVNYYGRKEFLRKEKKKKTRIDDC 359
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-14 (pep chromosome:WBcel235:I:5968009:5973320:-1 gene:WBGene00000232.1 transcript:B0207.12a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-14) HSP 1 Score: 225.328 bits (573), Expect = 8.633e-68 Identity = 111/302 (36.75%), Postives = 179/302 (59.27%), Query Frame = 1
Query: 232 PDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSL----------KDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELK--IPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSK 1101
PD LV + I + +I +D M+YS R+ W D RL +E EE V P + +IW+PD FF+N K+ H + PN L+R+ NG++LYS +L++V SC M L+ +P+D QNC I++ SY YT +++K+ W+ I + L+ +P F+ D++ T CT S T+TG Y+CL+ + L R+ YL Y+PS ++++VSW++FW+ D+VPAR+TLG+ +LL + + +++ LP VSY KAIDVW+ C+ F+ AL+EFA+ +++ ++
Sbjct: 52 PDTGGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAYERYEE---SGDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLRQSLPSFELQDVV-TDYCT--SLTNTGEYSCLRTRMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINAKLPPVSYTKAIDVWIGVCLAFIFGALLEFALVNYAARKDMTQ 347
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-14 (pep chromosome:WBcel235:I:5967250:5973320:-1 gene:WBGene00000232.1 transcript:B0207.12a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-14) HSP 1 Score: 225.328 bits (573), Expect = 8.633e-68 Identity = 111/302 (36.75%), Postives = 179/302 (59.27%), Query Frame = 1
Query: 232 PDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSL----------KDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELK--IPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSK 1101
PD LV + I + +I +D M+YS R+ W D RL +E EE V P + +IW+PD FF+N K+ H + PN L+R+ NG++LYS +L++V SC M L+ +P+D QNC I++ SY YT +++K+ W+ I + L+ +P F+ D++ T CT S T+TG Y+CL+ + L R+ YL Y+PS ++++VSW++FW+ D+VPAR+TLG+ +LL + + +++ LP VSY KAIDVW+ C+ F+ AL+EFA+ +++ ++
Sbjct: 52 PDTGGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAYERYEE---SGDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLRQSLPSFELQDVV-TDYCT--SLTNTGEYSCLRTRMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINAKLPPVSYTKAIDVWIGVCLAFIFGALLEFALVNYAARKDMTQ 347
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-1 (Glutamate-gated chloride channel alpha [Source:UniProtKB/Swiss-Prot;Acc:G5EBR3]) HSP 1 Score: 223.787 bits (569), Expect = 1.065e-66 Identity = 112/297 (37.71%), Postives = 180/297 (60.61%), Query Frame = 1
Query: 214 YKKQERPDENNTTLVMIYIKIL--AIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELK--IPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRN 1092
Y + RP +N V++ + +L I +DV M+YS + LR++WID RL + + + + V ++ +IW+PD FF N K+ Y H + PN L+R+ +G VLYS ++++V SC M LQ +PMD Q C I++ SY YT +++++ W+ + ++ L +P F + T CT S T+TG Y+CL+ I L R+ YL Y+PS ++++VSW++FW A+PAR+TLG+ +LL + + ++S LP VSYIKAIDVW+ AC+ F+ AL+EFA+ + +
Sbjct: 75 YDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQ---PDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNT-STTYCT--SVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANKQ 365
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0343788) HSP 1 Score: 233.417 bits (594), Expect = 3.231e-70 Identity = 138/449 (30.73%), Postives = 230/449 (51.22%), Query Frame = 1
Query: 163 YLSTQERIRNKLLDKIVYKKQERPDENNTT----LVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYI 1497
+ ++++ +++L Y + RP N T +V + I + +I +D M+YS + R+ W D RL+++ ++ Y ++ + + +W+PDLFF N K+G+ HN+ PN +R+ PNG VLYS ++++ +C M L+ +P+D Q C + + SYG+T +L F W+ D + V K L +P F T + T C +S T+TG Y+CLK + R+ YL Y+P ++++VSW++FW+ AVPAR++LG+ +LL + ++++LP VSY KAIDVW C+ FV AL+EFA+ + ++K+ ++ ++ +L S + + G G KP+ P D L Q EV ++ N + K P +K ID SR FP F L+N YW Y+
Sbjct: 29 FREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKA-NMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARG----GGQQKPLVRHPG--DPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKR-------IDVISRITFPLVFALFNLVYWSTYL 456
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: HisCl1 (gene:FBgn0037950 transcript:FBtr0082470) HSP 1 Score: 231.491 bits (589), Expect = 7.145e-70 Identity = 117/298 (39.26%), Postives = 179/298 (60.07%), Query Frame = 1
Query: 214 YKKQERPDE-NNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKS 1104
Y K P T+V ++ +L++DS++ M Y TD++L Q+W D RLR L E I+ IW PD FF+N KK H M+ PN+ + L + +LY KLT+V SC M+ +++P DTQ C + I S +T+E+L F W D + V E+++P+ D + T DCT + STGN+TCL + L R+LG +L TY+PS LI+++SW++FW+ +A+PAR+TLG+ SLL + +LP VSY+KAIDVW+ +C +FV +L+EFA+ + + +K+
Sbjct: 67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLR---LPENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQLDISNNYTT-DCTIE--YSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKA 358
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0343789) HSP 1 Score: 232.261 bits (591), Expect = 8.286e-70 Identity = 138/449 (30.73%), Postives = 229/449 (51.00%), Query Frame = 1
Query: 163 YLSTQERIRNKLLDKIVYKKQERPDENNTT----LVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYI 1497
+ ++++ +++L Y + RP N T +V + I + +I +D M+YS + R+ W D RL+++ ++ Y ++ + + +W+PDLFF N K+G+ HN+ PN +R+ PNG VLYS ++++ +C M L+ +P+D Q C + + SYG+T +L F W+ D + V K L +P F T + T C +S T+TG Y+CLK + R+ YL Y+P ++++VSW++FW+ AVPAR++LG+ +LL + ++++LP VSY KAIDVW C+ FV AL+EFA+ + + + + ++ ++ +L S + AT KP+ P D L Q EV ++ N + K P S+S ID SR FP F L+N YW Y+
Sbjct: 29 FREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDRAADMHKE--NMKKKRRDLEQASLDAASDLLDTDS---------------NATFAMKPLVRHPG--DPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRS---KRIDVISRITFPLVFALFNLVYWSTYL 448
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335418) HSP 1 Score: 232.261 bits (591), Expect = 8.815e-70 Identity = 138/450 (30.67%), Postives = 231/450 (51.33%), Query Frame = 1
Query: 163 YLSTQERIRNKLLDKIVYKKQERPD-----ENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYI 1497
+ ++++ +++L Y + RP +N T V + + + +I +D +M+YS + R+ W D RL+++ ++ Y ++ + + +W+PDLFF N K+G+ HN+ PN +R+ PNG VLYS ++++ +C M L+ +P+D Q C + + SYG+T +L F W+ D + V K L +P F T + T C +S T+TG Y+CLK + R+ YL Y+P ++++VSW++FW+ AVPAR++LG+ +LL + ++++LP VSY KAIDVW C+ FV AL+EFA+ + ++K+ ++ ++ +L S + AT KP+ P D L Q EV ++ N + K P S+S ID SR FP F L+N YW Y+
Sbjct: 29 FREKEKKVLDQILGAGKYDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYC--NSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKA-NMHKENMKKKRRDLEQASLDAASDLLDTDS---------------NATFAMKPLVRHPG--DPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRS---KRIDVISRITFPLVFALFNLVYWSTYL 450
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: HisCl1 (gene:FBgn0037950 transcript:FBtr0082471) HSP 1 Score: 231.106 bits (588), Expect = 9.189e-70 Identity = 117/298 (39.26%), Postives = 179/298 (60.07%), Query Frame = 1
Query: 214 YKKQERPDE-NNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKS 1104
Y K P T+V ++ +L++DS++ M Y TD++L Q+W D RLR L E I+ IW PD FF+N KK H M+ PN+ + L + +LY KLT+V SC M+ +++P DTQ C + I S +T+E+L F W D + V E+++P+ D + T DCT + STGN+TCL + L R+LG +L TY+PS LI+++SW++FW+ +A+PAR+TLG+ SLL + +LP VSY+KAIDVW+ +C +FV +L+EFA+ + + +K+
Sbjct: 67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLR---LPENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQLDISNNYTT-DCTIE--YSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKA 358
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3]) HSP 1 Score: 239.195 bits (609), Expect = 2.923e-72 Identity = 154/485 (31.75%), Postives = 243/485 (50.10%), Query Frame = 1
Query: 76 IEIRFWKIFLEFFTVFILVNSTTCDISSKYLSTQERIR-NKLLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTS--KSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
I I + F F FI + S +I S Q+ + + LDK++ Y + RP+ + V I I + S+ M Y +V+LRQ W D RL + + S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + + V +L +P+F + + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ + + I EE+ F + K G + PP + +L+ E + K +R K ID SR +FP FL++N FYW+ Y VL
Sbjct: 6 IRILYVLSFFFFQGGFIRLGSCKEEIKSSSRPAQKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYSEYPD----ASLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRRQRIEEELVRESRGFYFRGYGLGHCLQTKD-----------GTAVEGSSVFAPPPPVQVLY-----DGEAVRKRFVDRAK--------------------RIDTISRAVFPLSFLIFNVFYWITYKVL 448
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3]) HSP 1 Score: 238.81 bits (608), Expect = 4.363e-72 Identity = 154/483 (31.88%), Postives = 245/483 (50.72%), Query Frame = 1
Query: 76 IEIRFWKIFLEFFTVFILVNSTTCDISSKYLSTQERIR-NKLLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
I I + F F FI + S +I S Q+ + + LDK++ Y + RP+ + V I I + S+ M Y +V+LRQ W D RL + + S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + + V +L +P+F + + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ R E +L+ S + + + G++ A PP + +L+ E + K +R K ID SR +FP FL++N FYW+ Y VL
Sbjct: 6 IRILYVLSFFFFQGGFIRLGSCKEEIKSSSRPAQKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYSEYPD----ASLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRRQRIEEDLVRES----RGFYFRGYGLGHCLQTKDGTAVEGSSVFAP-----PPPVQVLY-----DGEAVRKRFVDRAK--------------------RIDTISRAVFPLSFLIFNVFYWITYKVL 448
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4b (glycine receptor, alpha 4b [Source:ZFIN;Acc:ZDB-GENE-020402-2]) HSP 1 Score: 240.35 bits (612), Expect = 6.557e-72 Identity = 156/499 (31.26%), Postives = 250/499 (50.10%), Query Frame = 1
Query: 91 WKIFLEFFTVFILVNSTTCDISSKYLSTQERIRNK------LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLK----------------RNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
W+I LE V + + SK L + +R K LDK++ Y + RP+ + V I I + S+ M Y +V+LRQ W D RL ++ + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT++ SC M+L+ FPMDTQ C + + S+GYT+ +L F W + V +L +P+F + + CT+ +TG +TC++ L RQ+G YL Y+PS+L +++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V + RN + S Q+ + N+ + S+ + + R + + P GID S + +E + F +++ ++K ID SR +FP FL++N FYW+ Y VL
Sbjct: 51 WRILLELLLVCWMFEGVIRCVFSKELKSPS-VRTKPMSPSDFLDKLMGKTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQYKEFFRLRRKLRQEQRNRAASGQAGAAETKNKSNNVTGGT---------PSRNAQRQCSACAREEQLASQNQDLYFPGF--GIDTSLSGDGPLSEAAAMFAGLPPGHALFDIRRRFVEQAKR-----IDTISRAVFPLSFLVFNVFYWVTYKVL 526
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 236.113 bits (601), Expect = 3.026e-71 Identity = 142/443 (32.05%), Postives = 231/443 (52.14%), Query Frame = 1
Query: 190 NKLLDKIV-YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTS-KSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNN--PSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
+KL+ K+ Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS ++T+V +C M+L+ FPMD Q C + + S+GYT+ +L F W + V L +P+F + + CT+ +TG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A + +++ +Q L +E SF A G G+ + +NN P+ K ++E M+K +++K ID SR FP FL++N FYW+ Y ++
Sbjct: 39 DKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFQRRRRHLKEDEAGDGRFSF--------------------------AAYGMGPACLQAKDGMAIKGNNNNAPTSTNPPEKTVEE--------MRKLFISRAKR-----IDTVSRVAFPLVFLIFNIFYWITYKII 436
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3]) HSP 1 Score: 235.728 bits (600), Expect = 5.643e-71 Identity = 150/471 (31.85%), Postives = 243/471 (51.59%), Query Frame = 1
Query: 100 FLEFFTVFI-LVNSTTCDISSKYLSTQERIRNKLLDKIV-YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
F FF++ + L C + K +S + + +KL+ + Y + RP+ + V I I + S+ M Y +V+LRQ W D RL + + S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + + V +L +P+F + + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ R E +L+ S + + + G++ A PP + +L+ E + K +R K ID SR +FP FL++N FYW+ Y VL
Sbjct: 21 FFGFFSISLPLCFLYLCRPAQKPMSPSDFL-DKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYSEYPD----ASLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRRQRIEEDLVRES----RGFYFRGYGLGHCLQTKDGTAVEGSSVFAP-----PPPVQVLY-----DGEAVRKRFVDRAK--------------------RIDTISRAVFPLSFLIFNVFYWITYKVL 450
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: glrb (glycine receptor beta [Source:NCBI gene;Acc:779708]) HSP 1 Score: 248.054 bits (632), Expect = 2.122e-75 Identity = 156/487 (32.03%), Postives = 261/487 (53.59%), Query Frame = 1
Query: 124 ILVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD--TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDM----------LFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDST----------------IDNYSRFLFPACFLLYNCFYWLYYI 1497
+L+ + D++ ++ I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ + +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD T DI E +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + +++ LP+VSY+KAIDVWLIAC++F A+LVE+A+ +L N+ K +++ + + E + + N+ + + TGT I L G + L SN+ S L ++ + N + NN KS + ID YSR LFP CFL +N YWL Y+
Sbjct: 3 VLIQLSAEDLARVPANSTSNILNRLL--VSYDPRVRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLKLPN--DFRGSDALTVDPTMFKCLWKPDLFFANEKNANFHDVTQENILLFIFRDGDVLLSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQMEK-IALPQFDIKTEDI-EYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAQELPKVSYVKAIDVWLIACLLFGFASLVEYAVVQVLL--NSPKRIEAEKAKIAKAE-------------------QAEGKGANAAKKNTVNGTGTPIHISTLQVGENRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPSEAKRIDLYSRALFPFCFLFFNVIYWLVYL 461
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: glrb (glycine receptor beta [Source:NCBI gene;Acc:779708]) HSP 1 Score: 247.284 bits (630), Expect = 4.329e-75 Identity = 158/492 (32.11%), Postives = 264/492 (53.66%), Query Frame = 1
Query: 112 FTVFI-LVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD--TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDM----------LFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDST----------------IDNYSRFLFPACFLLYNCFYWLYYI 1497
F +F+ L+ + D++ ++ I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ + +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD T DI E +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + +++ LP+VSY+KAIDVWLIAC++F A+LVE+A+ +L N+ K +++ + + E + + N+ + + TGT I L G + L SN+ S L ++ + N + NN KS + ID YSR LFP CFL +N YWL Y+
Sbjct: 9 FQIFMDLIQLSAEDLARVPANSTSNILNRLL--VSYDPRVRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLKLPN--DFRGSDALTVDPTMFKCLWKPDLFFANEKNANFHDVTQENILLFIFRDGDVLLSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQMEK-IALPQFDIKTEDI-EYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAQELPKVSYVKAIDVWLIACLLFGFASLVEYAVVQVLL--NSPKRIEAEKAKIAKAE-------------------QAEGKGANAAKKNTVNGTGTPIHISTLQVGENRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPSEAKRIDLYSRALFPFCFLFFNVIYWLVYL 472
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: glrb (glycine receptor beta [Source:NCBI gene;Acc:779708]) HSP 1 Score: 246.128 bits (627), Expect = 2.742e-74 Identity = 155/479 (32.36%), Postives = 257/479 (53.65%), Query Frame = 1
Query: 148 DISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD--TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDM----------LFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDST----------------IDNYSRFLFPACFLLYNCFYWLYYI 1497
D++ ++ I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ + +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD T DI E +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + +++ LP+VSY+KAIDVWLIAC++F A+LVE+A+ +L N+ K +++ + + E + + N+ + + TGT I L G + L SN+ S L ++ + N + NN KS + ID YSR LFP CFL +N YWL Y+
Sbjct: 47 DLARVPANSTSNILNRLL--VSYDPRVRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLKLPN--DFRGSDALTVDPTMFKCLWKPDLFFANEKNANFHDVTQENILLFIFRDGDVLLSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQMEK-IALPQFDIKTEDI-EYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAQELPKVSYVKAIDVWLIACLLFGFASLVEYAVVQVLL--NSPKRIEAEKAKIAKAE-------------------QAEGKGANAAKKNTVNGTGTPIHISTLQVGENRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPSEAKRIDLYSRALFPFCFLFFNVIYWLVYL 497
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:100498379]) HSP 1 Score: 240.35 bits (612), Expect = 1.334e-72 Identity = 148/468 (31.62%), Postives = 234/468 (50.00%), Query Frame = 1
Query: 136 STTCDISSKYLSTQERIRNKL------LDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
TTC +SK + R KL LDK++ Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT+ +C M+L+ FPMD Q C + + S+GYT+ +L F W + V + L +P+F + + CT+ STG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A A + + R + + +E FS + + + + +A+P+ P DE K+ KK ID SR FP FL++N FYW+ Y ++
Sbjct: 15 GTTCLAASKEVGASARSSAKLMSPSDFLDKLMGKISGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTKH--YSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYA-AVNFVSRQHKELLRFRRRRRHHKEDENAEGRFSFAAYGMGPACLQAKDGISMKGNNNNNPASSAQPVSKSP---------------------DEMRKLFISRAKK-------------IDKVSRIGFPLVFLIFNTFYWIIYKIV 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:100498379]) HSP 1 Score: 238.424 bits (607), Expect = 5.904e-72 Identity = 146/460 (31.74%), Postives = 236/460 (51.30%), Query Frame = 1
Query: 154 SSKYLSTQERIRNKLLDKIV-YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTS--------KSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
SS L + +KL+ KI Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT+ +C M+L+ FPMD Q C + + S+GYT+ +L F W + V + L +P+F + + CT+ STG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A V +++ + +S + +L++E+ N FS + + + + +A+P+ P DE K+ KK ID SR FP FL++N FYW+ Y ++
Sbjct: 25 SSAKLMSPSDFLDKLMGKISGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTKH--YSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRRHHKSPMLNLLQEDEN-AEGRFSFAAYGMGPACLQAKDGISMKGNNNNNPASSAQPVSKSP---------------------DEMRKLFISRAKK-------------IDKVSRIGFPLVFLIFNTFYWIIYKIV 443
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra2 (glycine receptor, alpha 2 subunit [Source:MGI Symbol;Acc:MGI:95748]) HSP 1 Score: 242.662 bits (618), Expect = 1.204e-73 Identity = 145/449 (32.29%), Postives = 228/449 (50.78%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQH 1524
LDK++ Y + RP+ + V I I + SV M Y +++LRQ W DSRL + + +S + PS+ D IW PDLFF N K H++TT N L+R+ NG+VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ +E ++ S + + G A P+P P D + K+ +R K ID SR FP FL++N FYW+ Y + IR+ H
Sbjct: 47 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRES-------RFNFSGYGMGHCLQMKDGTAVKATPANPLPQPPKDAD-----------AIKKKFVDRAK--------------------RIDTISRAAFPLAFLIFNIFYWITYKI-IRHEDVH 450
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra4 (glycine receptor, alpha 4 subunit [Source:MGI Symbol;Acc:MGI:95750]) HSP 1 Score: 239.965 bits (611), Expect = 1.364e-72 Identity = 155/460 (33.70%), Postives = 237/460 (51.52%), Query Frame = 1
Query: 148 DISSKYLSTQERIRNKLLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQ--KELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
D+ S +Q + LDK++ Y + RP+ + V I I + SV M Y +V+LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W D AVQ + L +P+F D + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ R E +++ S + + G M + P P P LLKE + TM+K ++K ID SR +FP FL++N FYW+ Y VL
Sbjct: 30 DVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLE-DAPAVQVAEGLTLPQFILRDEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRES------RFYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTP----------------LLKEGE--------TMRKLYVDRAKR-----IDTISRAVFPFTFLVFNIFYWVVYKVL 447
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra3 (glycine receptor, alpha 3 subunit [Source:MGI Symbol;Acc:MGI:95749]) HSP 1 Score: 234.187 bits (596), Expect = 4.118e-70 Identity = 145/443 (32.73%), Postives = 231/443 (52.14%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQN-EVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
LDK++ Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W+ + V + L +P+F + + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A V +++ ++ R+ N S + ++ + S MG AK D + P+ +V+ K DE K+ KK ID SR FP FL++N FYW+ Y +L
Sbjct: 62 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQH------KELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRFSFTAYGMGPCLQAK---------DGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKK-------------IDTISRACFPLAFLIFNIFYWVIYKIL 470
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glrb (glycine receptor, beta subunit [Source:MGI Symbol;Acc:MGI:95751]) HSP 1 Score: 232.646 bits (592), Expect = 2.391e-69 Identity = 118/321 (36.76%), Postives = 203/321 (63.24%), Query Frame = 1
Query: 184 IRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD-TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREE 1140
I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD + IE +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + ++++ LP+VSY+KA+DVWLIAC++F A+LVE+A+ +L N K +++ + + E
Sbjct: 59 ILNRLL--VSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLP--SDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVML--NNPKRVEAEKARIAKAE 371
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 225.713 bits (574), Expect = 3.739e-68 Identity = 103/262 (39.31%), Postives = 168/262 (64.12%), Query Frame = 1
Query: 307 MQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRN 1092
M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K + H +TT N L+R+ NG VLYS ++T+ +C M+L+ FPMD Q C + + S+GYT+ +L F W+ + V L +P+F + + CT+ +TG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A V +++
Sbjct: 1 MDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQH 256
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q7TNC8|GLRA2_MOUSE (Glycine receptor subunit alpha-2 OS=Mus musculus OX=10090 GN=Glra2 PE=1 SV=1) HSP 1 Score: 242.662 bits (618), Expect = 8.419e-73 Identity = 145/449 (32.29%), Postives = 228/449 (50.78%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQH 1524
LDK++ Y + RP+ + V I I + SV M Y +++LRQ W DSRL + + +S + PS+ D IW PDLFF N K H++TT N L+R+ NG+VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ +E ++ S + + G A P+P P D + K+ +R K ID SR FP FL++N FYW+ Y + IR+ H
Sbjct: 47 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRES-------RFNFSGYGMGHCLQMKDGTAVKATPANPLPQPPKDAD-----------AIKKKFVDRAK--------------------RIDTISRAAFPLAFLIFNIFYWITYKI-IRHEDVH 450
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P23416|GLRA2_HUMAN (Glycine receptor subunit alpha-2 OS=Homo sapiens OX=9606 GN=GLRA2 PE=1 SV=1) HSP 1 Score: 242.662 bits (618), Expect = 9.969e-73 Identity = 144/449 (32.07%), Postives = 228/449 (50.78%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQH 1524
LDK++ Y + RP+ + V I I + SV M Y +++LRQ W DSRL + + +S + PS+ D IW PDLFF N K H++TT N L+R+ NG+VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ +E ++ S + + G A P+P P + + K+ +R K ID SR FP FL++N FYW+ Y + IR+ H
Sbjct: 47 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRES-------RFNFSGYGMGHCLQVKDGTAVKATPANPLP-----------QPPKDGDAIKKKFVDRAK--------------------RIDTISRAAFPLAFLIFNIFYWITYKI-IRHEDVH 450
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q9GJS9|GLRB_BOVIN (Glycine receptor subunit beta OS=Bos taurus OX=9913 GN=GLRB PE=2 SV=1) HSP 1 Score: 241.506 bits (615), Expect = 8.819e-72 Identity = 145/465 (31.18%), Postives = 253/465 (54.41%), Query Frame = 1
Query: 148 DISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD-TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKP---------IPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTM---KKPNNTKSK-SSVDSTIDNYSRFLFPACFLLYNCFYWLYYI 1497
D++ ++ I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD + IE +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + ++++ LP+VSY+KA+DVWLIAC++F A+LVE+A+ +L N K +++ + + E + K+ + + + T+K + +LP ++ S + K ++ N + + KKP K + ID Y+R LFP CFL +N YW Y+
Sbjct: 47 DLARVPANSTSNILNRLL--VSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLP--SDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVML--NNPKRVEAEKARIAKAEQAVGKGGNVAKKNTVNGASTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFEL------SNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q61603|GLRA4_MOUSE (Glycine receptor subunit alpha-4 OS=Mus musculus OX=10090 GN=Glra4 PE=1 SV=3) HSP 1 Score: 239.965 bits (611), Expect = 9.541e-72 Identity = 155/460 (33.70%), Postives = 237/460 (51.52%), Query Frame = 1
Query: 148 DISSKYLSTQERIRNKLLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQ--KELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
D+ S +Q + LDK++ Y + RP+ + V I I + SV M Y +V+LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W D AVQ + L +P+F D + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ R E +++ S + + G M + P P P LLKE + TM+K ++K ID SR +FP FL++N FYW+ Y VL
Sbjct: 30 DVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLE-DAPAVQVAEGLTLPQFILRDEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRES------RFYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTP----------------LLKEGE--------TMRKLYVDRAKR-----IDTISRAVFPFTFLVFNIFYWVVYKVL 447
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P48167|GLRB_HUMAN (Glycine receptor subunit beta OS=Homo sapiens OX=9606 GN=GLRB PE=1 SV=1) HSP 1 Score: 241.121 bits (614), Expect = 1.022e-71 Identity = 150/474 (31.65%), Postives = 255/474 (53.80%), Query Frame = 1
Query: 148 DISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFD-TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVL---------KRNTSKSWQSDVCSLIREEINL-------MHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSS------VDSTIDNYSRFLFPACFLLYNCFYWLYYI 1497
D++ ++ I N+LL + Y + RP+ + V++ I I + S+ M Y +++LRQ W D RL+ +F+ ++ V P++ +W PDLFF N K H++T N L+ + +G+VL S +L++ SC ++L FPMDTQ C++ + S+GYT ++L+F W++ D + ++K + +P+FD + IE +CT+ TG YTC++ I TL RQ+G Y+ Y P++LI+++SW++FW++ DA AR+ LG+ S+L + + ++++ LP+VSY+KA+DVWLIAC++F A+LVE+A+ +L K +K+ Q+D + N +H S + ++ SN I+G+ LP ++ S + K ++ N + + K NN K + ID Y+R LFP CFL +N YW Y+
Sbjct: 47 DLARVPANSTSNILNRLL--VSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLP--SDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTK-YYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGS---------LPRDFEL------SNYDCYGKPIEVNNGLGKSQAK--NNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL 497
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A183KT92 (Uncharacterized protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS18282 PE=3 SV=1) HSP 1 Score: 446.047 bits (1146), Expect = 8.348e-149 Identity = 225/480 (46.88%), Postives = 310/480 (64.58%), Query Frame = 1
Query: 184 IRNKLLDKIV--YKKQERPDE--NNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTS--FXXXXXXXXXXXXXXXXXXXXXRVG--IMGATGTAKPIPNLP----PGIDM--------------LFSNNPSQ-----------NEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRY 1512
IR+++++ + Y+ RP E NTT+V +YI + AI SVDVR M+Y+ D+ LRQAW D RL W+ +E+FKHY NIVSP K++IWLPDLFFRNGK+G +H MT N L+R+QPNGE+LYSQK+TM +CQMEL+ FPMDTQ C++NIGSYGYTLE++ F WR + + + L+I EFD P+++ DCT +TSTG YTCL A TL RQLG +LASTY+P+ILI++VSW+NFWVS++A+PAR+ L LL+LLG++ + S +S+LPRVSYIKAID+W IACI F L+EFAIA+ + +R WQ +V L+R E+ ++ + S +++ ++ +VG I A I N P P M + S P + N+ L LD K + +P K +S+ S ID+YSRF+FPACFLLYNCFYWLYY+V++++
Sbjct: 8 IRDEIVETLFANYQSHVRPGELIRNTTVVTVYISVSAITSVDVRNMEYTIDMLLRQAWYDPRLAWDQIEKFKHYTKNIVSPVFKEKIWLPDLFFRNGKEGRLHKMTCENLLIRIQPNGEILYSQKITMRMACQMELRTFPMDTQECDMNIGSYGYTLEQVSFVWRNISPVTLPENLQISEFDPPEVVRAYDCTSGYSTSTGQYTCLNATFTLQRQLGYWLASTYIPNILIMVVSWLNFWVSLEAIPARVNLSLLTLLGVITQSTSYASSLPRVSYIKAIDIWTIACITFNSGVLLEFAIASHLARRQKVSEWQVEVRKLVRRELARWCSACQLQYAQRGPSALSAYSASSRSNEKVGEYINSVAAAAFAIQNSPVLERPSPQMSVRLTKSGLMSMANIKSGKPDKVSKGVFYELVTNDSALTALDTTQKDALLPTNEPQRVKKPASM-SKIDSYSRFVFPACFLLYNCFYWLYYLVIVKH 486
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A430QCT3 (Uncharacterized protein OS=Schistosoma bovis OX=6184 GN=DC041_0010377 PE=3 SV=1) HSP 1 Score: 444.891 bits (1143), Expect = 5.768e-148 Identity = 225/480 (46.88%), Postives = 310/480 (64.58%), Query Frame = 1
Query: 184 IRNKLLDKIV--YKKQERPDE--NNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTS--FXXXXXXXXXXXXXXXXXXXXXRVG--IMGATGTAKPIPNLP----PGIDM--------------LFSNNPSQ-----------NEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRY 1512
IR+++++ + Y+ RP E NTT+V +YI + AI SVDVR M+Y+ D+ LRQAW D RL W+ +E+FKHY NIVSP K++IWLPDLFFRNGK+G +H MT N L+R+QPNGE+LYSQK+TM +CQMEL+ FPMDTQ C++NIGSYGYTLE++ F WR + + + L+I EFD P+++ DCT +TSTG YTCL A TL RQLG +LASTY+P+ILI++VSW+NFWVS++A+PAR+ L LL+LLG++ + S +S+LPRVSYIKAID+W IACI F L+EFAIA+ + +R WQ +V L+R E+ ++ + S +++ ++ +VG I A I N P P M + S P + N+ L LD K + +P K +S+ S ID+YSRF+FPACFLLYNCFYWLYY+V++++
Sbjct: 32 IRDEIVETLFANYQSHVRPGELIRNTTVVTVYISVSAITSVDVRNMEYTIDMLLRQAWYDPRLAWDQIEKFKHYTKNIVSPVFKEKIWLPDLFFRNGKEGRLHKMTCENLLIRIQPNGEILYSQKITMRMACQMELRTFPMDTQECDMNIGSYGYTLEQVSFVWRNISPVTLPENLQISEFDPPEVVRAYDCTSGYSTSTGQYTCLNATFTLQRQLGYWLASTYIPNILIMVVSWLNFWVSLEAIPARVNLSLLTLLGVITQSTSYASSLPRVSYIKAIDIWTIACITFNSGVLLEFAIASHLARRQKVSEWQVEVRKLVRRELARWCSACQLQYAQRGPSALSAYSASSRSNEKVGEYINSVAAAAFAIQNSPVLERPSPQMSVRLTKSGLMSMANIKSGKPDKVSKGVFYELVTNDSALTALDTTQKDALLPTNEPQRVKKPASM-SKIDSYSRFVFPACFLLYNCFYWLYYLVIVKH 510
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A095A7B3 (Glycine receptor subunit alpha-3 (Fragment) OS=Schistosoma haematobium OX=6185 GN=MS3_10138 PE=3 SV=1) HSP 1 Score: 444.506 bits (1142), Expect = 7.323e-148 Identity = 225/480 (46.88%), Postives = 309/480 (64.38%), Query Frame = 1
Query: 184 IRNKLLDKIV--YKKQERPDE--NNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTS--FXXXXXXXXXXXXXXXXXXXXXRVG--IMGATGTAKPIPNLP----PGIDM--------------LFSNNPSQ-----------NEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRY 1512
IR+++++ + Y+ RP E NTT+V +YI + AI SVDVR M+Y+ D+ LRQAW D RL W+ +E+FKHY NIVSP K++IWLPDLFFRNGK+G +H MT N L+R+QPNGE+LYSQK+TM +CQMEL+ FPMDTQ C++NIGSYGYTLE++ F WR + + + L+I EFD P+++ DCT +TSTG YTCL A TL RQLG +LASTY+P+ILI++VSW+NFWVS++A+PAR+ L LL+LLG++ + S +S+LPRVSYIKAID+W IACI F L+EFAIA+ + +R WQ +V L+R E+ ++ + S +++ + +VG I A I N P P M + S P + N+ L LD K + +P K +S+ S ID+YSRF+FPACFLLYNCFYWLYY+V++++
Sbjct: 32 IRDEIVETLFANYQSHVRPGELIRNTTVVTVYISVSAITSVDVRNMEYTIDMLLRQAWYDPRLAWDQIEKFKHYTKNIVSPVFKEKIWLPDLFFRNGKEGRLHKMTCENLLIRIQPNGEILYSQKITMRMACQMELRTFPMDTQECDMNIGSYGYTLEQVSFVWRNISPVTLPENLQISEFDPPEVVRAYDCTSGYSTSTGQYTCLNATFTLQRQLGYWLASTYIPNILIMVVSWLNFWVSLEAIPARVNLSLLTLLGVITQSTSYASSLPRVSYIKAIDIWTIACITFNSGVLLEFAIASHLARRQKVSEWQVEVRKLVRRELARWCSACQLQYAQRGPSALSAYSASSRPNEKVGEYINSVAAAAFAIQNSPVLERPSPQMSVRLTKSGLMSMANIKSGKPDKVSKGVFYELVTNDSALTALDTTQKDALLPTNEPQRVKKPASM-SKIDSYSRFVFPACFLLYNCFYWLYYLVIVKH 510
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A068Y380 (Glycine receptor subunit beta OS=Echinococcus multilocularis OX=6211 PE=3 SV=1) HSP 1 Score: 440.269 bits (1131), Expect = 5.210e-146 Identity = 216/452 (47.79%), Postives = 301/452 (66.59%), Query Frame = 1
Query: 187 RNKLLDKIV--YKKQERPDE--NNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLL--KELDERNKMSRFTMKKPNNTKSKSSV-----DSTIDNYSRFLFPACFLLYNCFYWLYYIVLIR 1509
R+ +L+KI YK ERP E + +T+V + IKI +I S+DVR M Y D LRQAWID RL W+ + E K++ +VSP +K+++WLPDLFFRNGK+GY+H MT PNYL+R+ PNG+VLYSQK+TM F+CQM+LQ FPMD Q C+INIGSYGYTL ELKF W I + K++++ EF+TP T DCT ++TSTGNY+CL A ++ R+LGSYL +TY+P++LIIMVSW++FWVS+DA PAR+ LGL+SLLGI+ A S+ S LPRVSYIKAID+WLI IIFVI+ LVE+A+A + L++ W++D+C+++REE+ ++ + M A G + P ++ +Q E ++ + + E+ + R + N +K V +S ID YSRFLFP C+L+YN YWLYY+VL++
Sbjct: 98 RDDILEKIFLNYKTHERPTEQLDTSTIVQVNIKIQSIFSIDVRTMDYYVDALLRQAWIDPRLAWDKMLEHKNFTQPLVSPKMKNQLWLPDLFFRNGKEGYLHKMTLPNYLLRVYPNGQVLYSQKITMRFACQMDLQTFPMDVQVCDINIGSYGYTLSELKFVWSEKSPIELNKDMQLSEFNTPKAFATFDCTSQASTSTGNYSCLLAKFSIARRLGSYLVTTYIPNVLIIMVSWLSFWVSVDAAPARVPLGLMSLLGILTQASSLGSNLPRVSYIKAIDLWLIFSIIFVISVLVEYALAITYLRKTRKGQWKTDLCAIVREELARWCSA------------------CQQKELESMRAAGASVPKYQ---------ADYYTQMEAMIAFRGVAEQYRKRRLASARKNGVNTKIKVITGVTESVIDAYSRFLFPLCYLVYNACYWLYYLVLVK 522
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A183P0Y9 (Uncharacterized protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS8025 PE=3 SV=1) HSP 1 Score: 438.728 bits (1127), Expect = 1.267e-145 Identity = 221/484 (45.66%), Postives = 305/484 (63.02%), Query Frame = 1
Query: 184 IRNKLLDKIV--YKKQERPDE--NNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDV--------------CSL----------------------IREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPN-LPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRY 1512
IR+++++ + Y+ RP E NTT+V +YI + AI SVDVR M+Y+ D+ LRQAW D RL W+ +E+FKHY NIVSP K++IWLPDLFFRNGK+G +H MT N L+R+QPNGE+LYSQK+TM +CQMEL+ FPMDTQ C++NIGSYGYTLE++ F WR + + + L+I EFD P+++ DCT +TSTG YTCL A TL RQLG +LASTY+P+ILI++VSW+NFWVS++A+PAR+ L LL+LLG++ + S +S+LPRVSYIKAID+W IACI F L+EFAIA+ + +R WQ +V C L + E IN + + I++ + + + + G+M P+ + G+ N S L LD K + +P K +S+ S ID+YSRF+FPACFLLYNCFYWLYY+V++++
Sbjct: 32 IRDEIVETLFANYQSHVRPGELIRNTTVVTVYISVSAITSVDVRNMEYTIDMLLRQAWYDPRLAWDQIEKFKHYTKNIVSPVFKEKIWLPDLFFRNGKEGRLHKMTCENLLIRIQPNGEILYSQKITMRMACQMELRTFPMDTQECDMNIGSYGYTLEQVSFVWRNISPVTLPENLQISEFDPPEVVRAYDCTSGYSTSTGQYTCLNATFTLQRQLGYWLASTYIPNILIMVVSWLNFWVSLEAIPARVNLSLLTLLGVITQSTSYASSLPRVSYIKAIDIWTIACITFNSGVLLEFAIASHLARRQKVSEWQVEVRKLVRRELARWCSACQLQYAQRGPSALSAYSASSRSNEKVSEYINSVAAAAFAIQNSPVLERPSPQMSVRLTKSGLMSMANIKSGKPDKVSKGVFYELVTNDSA----LTALDTTQKDALLPTNEPQRVKKPASM-SKIDSYSRFVFPACFLLYNCFYWLYYLVIVKH 510
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 236.498 bits (602), Expect = 1.999e-71 Identity = 144/444 (32.43%), Postives = 228/444 (51.35%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTS--KSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
LDK++ Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K + H +TT N L+R+ NG VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W+ + V L +P+F D + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A V +++ + + S EE+ SF+ + + +N +T +P P +P K +E K+ KK ID SR FP FL +N FYW+ Y +L
Sbjct: 45 FLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSTKEEEVRESCLSFTANAGKDGTMTKPTNNA---------ASTPKGQPTPTVPQAG---------------KSTEEMRKIFIDRAKK-------------IDTVSRAGFPLAFLFFNIFYWVLYKIL 445
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra4b (glycine receptor, alpha 4b [Source:ZFIN;Acc:ZDB-GENE-020402-2]) HSP 1 Score: 236.498 bits (602), Expect = 2.319e-71 Identity = 144/442 (32.58%), Postives = 228/442 (51.58%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
LDK++ Y + RP+ + V I I + SV M Y +V+LRQ W D RL ++ + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W + V +L +P+F + + CT+ +TG +TC++ L RQ+G YL Y+PS+L +++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A A + + R + ++ + ++ F +S G + TA +LPPG + E+ + +D + ID SR +FP FL++N FYWL Y VL
Sbjct: 48 FLDKLMGKTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRLNVFLRQQWNDPRLAYKEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFQWLDIGPVQVADDLMLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYA-AVNFVSRQHKEFFRLRRRLREEQRQRAVNVFFPGYGLETFLS-------------GDGPISETAAMFASLPPGHALF--------EIRRRFIDRAKR---------------------IDTISRAVFPLSFLIFNVFYWLTYKVL 440
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 236.113 bits (601), Expect = 2.445e-71 Identity = 138/440 (31.36%), Postives = 229/440 (52.05%), Query Frame = 1
Query: 190 NKLLDKIV-YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
+KL+ K+ Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS ++T+V +C M+L+ FPMD Q C + + S+GYT+ +L F W + V L +P+F + + CT+ +TG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A + +++ ++ R +L + + + + + I G A P ++PP K ++E K+ K+ ID SR FP FL++N FYW+ Y ++
Sbjct: 42 DKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQH------KELLRFQRRRRHLKEDEAGEGRFSFAAYGMGPACLQAKDGMAIKGNNNNA-PTSSIPPE----------------KTVEEMRKLFISRAKR-------------IDTVSRVAFPLVFLIFNIFYWIIYKII 439
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 234.958 bits (598), Expect = 4.878e-71 Identity = 141/442 (31.90%), Postives = 224/442 (50.68%), Query Frame = 1
Query: 214 YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDST--IDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQHGS 1530
Y + RP+ + V I I + SV M Y +++LRQ W D RL + + S + PS+ D IW PDLFF N K H++TT N L+R+ +G VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V ++ Q + L R + + R G +G +S P + + + N + + + + K VD ID SR FP FL++N FYW+ Y + I+HG+
Sbjct: 46 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQKWNDPRLAYSEYPD----PSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLDEGPVQVAEGLTLPQFIMREEKELGYCTKHY--NTGKFTCIEVKFKLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQ------QKEFLRLKRRQKRNLKEEL---------------------REGRFHFSG---------------YSMAPCMKDGTVVKSATANAIQQPSALRDAEHNRKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKI-----IRHGT 434
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 234.958 bits (598), Expect = 8.848e-71 Identity = 137/441 (31.07%), Postives = 223/441 (50.57%), Query Frame = 1
Query: 181 RIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
RIR D K + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS ++T+V +C M+L+ FPMD Q C + + S+GYT+ +L F W + V L +P+F + + CT+ +TG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A + +++ ++ R +L + + + + + I G A P ++PP K ++E K+ K+ ID SR FP FL++N FYW+ Y ++
Sbjct: 54 RIRPNFKDPQGSKSDGTHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQH------KELLRFQRRRRHLKEDEAGEGRFSFAAYGMGPACLQAKDGMAIKGNNNNA-PTSSIPPE----------------KTVEEMRKLFISRAKR-------------IDTVSRVAFPLVFLIFNIFYWIIYKII 452
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008467.1 (pep scaffold:Pmarinus_7.0:GL477211:8305:20106:1 gene:ENSPMAG00000007648.1 transcript:ENSPMAT00000008467.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 238.039 bits (606), Expect = 1.468e-72 Identity = 144/454 (31.72%), Postives = 236/454 (51.98%), Query Frame = 1
Query: 190 NKLLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLE-EFKHYN-SNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQHG 1527
+++LDK++ Y + RP+ + V + I + S+ Y VYLRQ W D RL + H H + SNI IW PDLFF N K + H +TT N ++R+ NG V Y+ +LT+ SC M+L FPMDTQ C + + S+GYT ++ F+W +++ + L +P+F + I T CT+ STG++TC+ A TL+R++G YL YVPSILI+++SW++FW++++A PAR+ LG+ ++L + + ++LP+VSYIKA+D+W+ C++FV AAL+E+A A +V R + + + ++ + F + + G++ + + KP+ + P LL + + KM K + TIDN SR FP FL++N YW + V+++ + G
Sbjct: 43 SEVLDKLLGPSSGYNHRVRPNFGGPAVNVSCGVFIRSFGSIQEATSDYRMTVYLRQRWTDPRLAYSHYPVPLLHLDQSNI------KHIWKPDLFFDNEKSAHFHEITTDNKMLRIANNGVVDYAMRLTLTLSCPMDLHNFPMDTQMCSMYLESFGYTTADIVFHWNGPTPVSLFEGLTLPQFVLSNKISTGSCTK--TYSTGSFTCIFAKFTLHREMGFYLIQLYVPSILIVILSWVSFWINMEAAPARVALGITTVLTLTTQSTGARASLPKVSYIKAMDIWMATCLLFVFAALLEYA-AVNVTSRQSQGFMKKGRGNQKPIDLLVHKKMFWKFLVAENDNDLLYFTITIFTLNGLLPVSDSKKPV---------IVCIKP-----LLSLQETKEKMR----------KKYVACAQTIDNISRLFFPISFLIFNVVYWFAFKVMLKRNVHVG 463
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 229.95 bits (585), Expect = 2.887e-70 Identity = 108/275 (39.27%), Postives = 173/275 (62.91%), Query Frame = 1
Query: 268 IKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRN 1092
I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ +G VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W+ + V + L +P+F D + + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++
Sbjct: 12 IFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWKQEGAVQVAEGLTLPQFVLKDEKDLVYCTKHY--NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQH 280
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 202.986 bits (515), Expect = 1.429e-61 Identity = 102/277 (36.82%), Postives = 166/277 (59.93%), Query Frame = 1
Query: 193 KLLDKIV-----YKKQERPDENNTTL---VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEE--FKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVS 993
+ LDK++ Y + RP+ T+ +YIK + S++ M Y ++LRQ WID RL + H E SNI IW PDLFF N K Y H +TT N ++R+ NG VL++ +LT+ SC M+L+ FPMDTQ C + + S+GYT+ +L F+W + + + KEL +P+F I+T C + ++ TG+++C+ A L+R++G YL YVPS LI+++SW++FW++++A PAR+ LG+ ++L + + ++LP+V+
Sbjct: 5 EFLDKLLGPTSGYDHRIRPNFGGPTVNVNCSVYIK--SFGSIEETTMDYQVTIFLRQKWIDPRLTYSHYPEPYLDLDQSNI------QYIWRPDLFFDNEKSAYFHEVTTDNKMLRIFKNGLVLFTVRLTLTLSCPMDLRNFPMDTQMCYMFLESFGYTMADLSFHWDEEEPVIISKELVLPQFVLSSKIDTDSCDKLYSSGTGHFSCISARFVLHREMGFYLIQLYVPSALIVIISWVSFWINMEAAPARVALGITTVLTMTTQSTGARASLPKVT 273
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002305.1 (pep scaffold:Pmarinus_7.0:GL478144:76380:93696:1 gene:ENSPMAG00000002075.1 transcript:ENSPMAT00000002305.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 204.142 bits (518), Expect = 4.696e-60 Identity = 102/304 (33.55%), Postives = 178/304 (58.55%), Query Frame = 1
Query: 190 NKLLDKIVYKKQERPD-ENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIV--SPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRN 1092
++L+ + Y + RP+ + LV + + + ++ M Y +YL+Q+WIDSR+ E + HY + + + + D +W PDLFF N K H + ++ N + +S L++ +C M L+ +P+DTQ C IN+ S+GYT ++L F W + + V L P+F + E DC+++ T G ++C+ A L+R +G YL Y PS L++++SW++FW+S+++ PAR++LG+ ++L + S ++ LP++SYIKA+DVW+ AC +FV AAL+E + SV K++
Sbjct: 36 DELIKESSYDGRLRPNMYGSPVLVNCSVLVKSFGPIEENTMDYMMLIYLQQSWIDSRI--ESIYSAGHYQKDFLDLANNYIDTVWTPDLFFENEKSAAFHEIHCRFSIIVHATNNKTCFSLVLSLTLACPMNLEYYPLDTQECRINLESFGYTTQDLIFQWDENEPLVVATNLYTPKFKLSNHTELGDCSKEYLT--GTHSCINATFYLHRDMGYYLIQVYFPSCLLVIISWLSFWLSVESTPARVSLGITTILTVTTQMTSANAALPKMSYIKAMDVWMAACQVFVFAALLE-STVVSVTKQH 334
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3]) HSP 1 Score: 194.897 bits (494), Expect = 2.123e-56 Identity = 129/463 (27.86%), Postives = 211/463 (45.57%), Query Frame = 1
Query: 157 SKYLSTQERIRNKLLDKIVYKKQERPDENNTTLVM-IYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFK--HYNSNIV--SPSLKDEIWLPDLFFRNGKKGYIHN---MTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLP---------PGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYY 1494
S +LS IR+ Y + RP+ + +V+ I + V+ M YS +++LRQ W D R+ L K YN++ + S D +W PDLFF N K +T Y+ +L++V +C M L+ +PMD Q C I + SYGYT +L F W + ++ + P+F + +CT++ + G ++C+KA L+R +G YL Y+PS L++++SW++FW++++A PAR+ LG+ ++L + S ++ LP+VSYIKAIDVW+ AC +FV +AL+EFA +R+ D + E+ + R + +P + P PG+ S N + DE + + ID SR +FP F+++N FYW+ Y
Sbjct: 42 SPFLSMDNVIRDT-----GYDSRMRPNVDGPPVVVNCSILVKGFGPVEEATMDYSINIFLRQTWNDPRI----LNVLKSIEYNTDFLDLGNSFVDSVWKPDLFFENEKSAAFQMYQLVTGFKYMYTFAMWITCFLCFRLSLVLACPMSLEVYPMDAQYCSIYLESYGYTTNDLIFQWNDTEPVSFGAGVSTPKFTLSNETFLGECTKE--YTYGTFSCVKATFFLDRDMGYYLIQVYIPSCLLVIISWLSFWLNVEAAPARVGLGITTILTVTTQMTSANAALPKVSYIKAIDVWMGACQVFVFSALLEFAAVNMATRRHGISPSHHDGDHGTKGELPI-----------------------EWKRHRHANVSSVRRPQRHRPERDCRSQGKPGVFHTNSRRDENNATRVHVSDEEWRYQSLLHAR------------RIDYISRVIFPTVFMIFNIFYWVIY 458
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO34692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNK5]) HSP 1 Score: 205.297 bits (521), Expect = 5.287e-62 Identity = 106/290 (36.55%), Postives = 182/290 (62.76%), Query Frame = 1
Query: 313 YSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLK--DEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWR----TFDTIAVQKELKIPEFDTPDI-IETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAI----ATSVLKRNTSKSWQSDVCSLIREEINL 1149
++ D+YLRQ W D RL ++ + N+++++ + + DEIW+P +F N KK Y H++TT NYL+ ++PNG+V YS +LT+ +C++ LQ FP D Q CE+ + SYGY ++ + W T D + + ++L++P+F ++ +E + + + G ++ L A T +R+LG Y+ TY+PS+L + +SW +FW+S D+ PAR+ LG+ ++L ++ ++ S + LP+VSY KAID +L+ C+++V AL+E+AI A V +RN +K REEI +
Sbjct: 2 FTIDMYLRQYWRDPRLIFDPVPV----NTDVLTLNRQTIDEIWIPSTYFFNAKKAYFHDVTTENYLLMIKPNGDVFYSVRLTITMACKLTLQMFPHDVQVCEMMLESYGYQATDVYYRWNSRNSTGDVVYISEDLEMPQFKITNVKLEE----RTNIYNIGPHSALIAKFTFHRRLGYYMIQTYIPSMLTVTISWFSFWISPDSPPARVGLGITTVLTMITISNSARAPLPKVSYTKAIDWFLLMCLVYVFGALMEYAIVNFYACKVQQRNRNK----------REEIRV 273
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO30047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1W8]) HSP 1 Score: 197.593 bits (501), Expect = 6.680e-59 Identity = 108/303 (35.64%), Postives = 180/303 (59.41%), Query Frame = 1
Query: 181 RIRNKLLDKIVYKKQERPDEN-NTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIA---VQKELK-IPEFD-TPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIA 1071
RI + +L Y K+ RP+ +V + +L+ID+++V M Y+ D++LRQ+W+D RL H + SN V D+IWLPD +F N K+G H +T N ++ +QP+G+V Y+ ++T+ SC M L+ FPMDTQ+C + + SYGY+ + + F W D V + LK +P++ P+ + C GN++ +KA+ T R ++ Y P LI++VSW++F + + PARITLG+ S+L +V + +++++P+V+Y+K ID +LI C +FV A LVE+++
Sbjct: 3 RILDSILTAEKYDKRLRPNYGAGPVIVTVGFWVLSIDTINVVDMDYTLDIFLRQSWVDERL--SHDLNTTMFLSNTV----MDKIWLPDSYFVNAKQGSFHKVTKDNMMVMIQPDGQVQYNARVTIRASCPMNLRKFPMDTQHCPLTLESYGYSSDHIVFKWEIEDGDGLGFVPESLKMLPQYKLAPNEPRSELC----FVIPGNWSGIKALFTFERMYSYFVIHVYGPCALIVVVSWVSFLLPKEQAPARITLGVTSVLTVVTILNMLNNSMPKVNYVKTIDKYLIGCFLFVFATLVEYSLV 295
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO35410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK4]) HSP 1 Score: 194.126 bits (492), Expect = 2.292e-57 Identity = 101/319 (31.66%), Postives = 188/319 (58.93%), Query Frame = 1
Query: 136 STTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTLVMIYIKILA--IDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWR----TFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIAT 1074
ST + KY ++ ++N LL+ Y ++ RP +V +Y+ + I ++ M ++ D+YLRQ W D RL++E +S + +IW+P +F KK Y H++TT NYL++++P+G + YS +LT+ SC+++L+ FP DTQ+C +++ SYGY ++ + W I + +L++P+F+ ++ + + + GN++ L A + R++G +L TY+PS +I+++SW++FW+ + PAR+ LG+ ++L + + S + LP+VSY+KAID +L+ C+IFV +++E+ T
Sbjct: 10 STKSTPAGKYWNSTLVLKN-LLEG--YDRRIRPGSKGEPVV-VYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERLQFETQTPGAMLT---LSSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQVKPDGSLFYSIRLTITTSCRLDLRDFPHDTQSCSLSLESYGYQSTDVLYVWNERLDNTSAIYIHDDLELPQFE---VLGVSRSAKMNKYNIGNHSSLVANFRMKRRIGYFLIDTYIPSTIIVIISWISFWIDPETAPARVALGITTVLTMTTLISSARANLPKVSYVKAIDWYLLLCLIFVFGSILEYTCVT 318
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO37555 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFG6]) HSP 1 Score: 196.052 bits (497), Expect = 7.371e-57 Identity = 129/453 (28.48%), Postives = 234/453 (51.66%), Query Frame = 1
Query: 196 LLDKIV--YKKQERPD-ENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYW--RTFDTIAVQKELK-IPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPN-LPPGIDMLFSNNP---------SQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDS-TIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
LLD ++ Y + RPD + V + +L+ID+++V M Y D +LRQ W D RL+ + ++ +S ++ D+IW+PD +F N K H++TT N ++ + P+G V Y+ ++T+ SC M L+ FP D QNC I+I SYGY+ + +++ W R+ + IAV K+++ +P+++ DI + T A GN++ L A R+ G ++ Y P LI+++SW++F + ++ ARI LG+ S+L I + +++++P+VSY+KA+D +LI C +FV A L+E+ + ++ ++ D+ + E + H S A IPN P + FS + + ++V+LK ++ + +P K + +D+ ID ++R LFP F+ +N Y++ + +
Sbjct: 9 LLDNLIQGYDPRLRPDFGGDPVTVTVGFWVLSIDAINVIDMDYRMDFFLRQLWRDPRLK------HRFDDTLALSNTMLDKIWVPDTYFVNSKMSKFHSVTTINKMLSISPDGLVHYNSRVTVKASCAMNLRMFPKDVQNCNIDIESYGYSADNVQYQWENRSDNGIAVNKKIRDMPQYNLSDINVSRHFTMYVA---GNWSGLTATFRFRRRSGYFIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTITTILNMLNNSMPKVSYVKAVDWYLIGCFLFVFAVLLEYTFVLYIDNEEVTE-YKKDLVNYSSESVK--HRS---------------------------PAHAMNGSIPNGYSPAV---FSEHGKKCGHNCHHAHHDVVLKREKHKSSYEQLGGCRP-RLKFPAVIDTECIDEFARVLFPFIFIAFNVIYFIVFFFI 418
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO34654 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNP9]) HSP 1 Score: 194.126 bits (492), Expect = 1.090e-55 Identity = 136/483 (28.16%), Postives = 243/483 (50.31%), Query Frame = 1
Query: 70 MEIEIRFWKIFLEFFTVFILVNSTTCDIS-SKYLSTQERIRNKLLDKIVYKKQERPDENNT-TLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNI-VSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIA---VQKELKI-PEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTI---DNYSRFLFPACFLLYNCFYWL 1488
+ +E+ FW I L V + + D + SK T ++L + Y + RP N+ LV +L+IDS++V+ M + D++LRQ W+D+RL +H N + +S ++ IWLPD +F+N K+ H +T+ N ++ + P G+V Y+ ++T+ SC M+L+ +P D Q+C + + SYGY++E + + W + V +++K+ P+F+ + + ++++ GN++ + A T R Y+ Y PS LI+++SW++F + D PAR+TLG+ S+L V + ++ +P+V+Y+KA+D +LIAC +FV A+L+E+++ + R + Q + E + + + + S + A G A PN F+ N + + LL + R+ + R D TI D YSR LFP F +N +YW+
Sbjct: 16 ISLEMLFWNILL---AVVVGSEARVRDYNRSKLEITMTDTLDELFKRPRYDPRLRPQYNDGPVLVTTGFWVLSIDSINVQDMAFGMDIFLRQNWVDNRL--DH-----GLNQTLSLSNAVMSNIWLPDSYFKNAKQANFHEVTSKNLMITIGPKGKVHYNTRVTLKASCSMDLRLYPFDIQHCPLIMESYGYSVEHIMYKWEKGEGDGMSFVPRDVKLLPQFNLTKLELS---SRNTQYVIGNWSGVMATFTFERTYSFYVIHIYGPSALIVLISWISFLLPRDQSPARVTLGVTSVLTEVTILTMSNNAMPKVNYVKAVDKYLIACFLFVFASLMEYSLILVLANRTMRREKQKRAAKRLAMEKENCSEHDPENSKLLLSPNIRCACHRRSPSSSLRNANGNAHQ-PN--------FALNVTHRDSLLVSI--RDILYR---------------DETILAVDEYSRKLFPLAFFAFNVYYWV 459
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra4a (glycine receptor subunit alpha-4-like [Source:NCBI gene;Acc:101156095]) HSP 1 Score: 239.965 bits (611), Expect = 9.941e-73 Identity = 152/481 (31.60%), Postives = 241/481 (50.10%), Query Frame = 1
Query: 100 FLEFFTVFILVNSTTCDISSKYLSTQERIRNKLLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTS-------KSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
F F FI ++S +I + + + LDK++ Y + RP+ + V I I + S+ M Y +V+LRQ W D RL + + NS + PS+ D IW PDLFF N K H +TT N L+R+ +G VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + + V +L +P+F + + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A V +++ + Q L+RE + + + + GA + + PP + M EV K +R K ID SR +FP FL++N FYWL Y VL
Sbjct: 14 FCFFQGSFIRLSSCKEEIKPASRAGPQLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQNWNDPRLAYSEYPD----NSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQDGSVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRQQRIEEELVRESRGFYFRGYGLGHCLQTKD----------------GAPLEGATVFSPPPPMTMY------DGEVFSKRFVDRAK--------------------RIDTISRAVFPLSFLIFNIFYWLTYKVL 446
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: ENSORLT00000025211.2 (glycine receptor subunit alpha-3 [Source:NCBI gene;Acc:101174559]) HSP 1 Score: 235.343 bits (599), Expect = 4.694e-71 Identity = 142/442 (32.13%), Postives = 227/442 (51.36%), Query Frame = 1
Query: 196 LLDKIV-----YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
LDK++ Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K + H +TT N L+R+ NG VLYS +LT+ SC M+L+ FPMD Q C + + S+GYT+ +L F W+ + V + L +P+F D + CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A V +++ S +EE+ S ++ + + ++ S + A T + P G E + K +R K ID SR FP FL +N FYW+ Y +L
Sbjct: 38 FLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYAEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFQWQENGPVQVAEGLTLPQFILKDESDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRHKSKTKEEVG---ESKLTSTAVMTSTPSISKDSKASVNNAVAPAANTTQNAPAAGGG--------GRSTEEMRKLFIDRAK--------------------KIDTVSRAGFPLAFLFFNIFYWVLYKIL 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 233.802 bits (595), Expect = 1.362e-70 Identity = 137/441 (31.07%), Postives = 226/441 (51.25%), Query Frame = 1
Query: 190 NKLLDKIV-YKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLL-KELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
+KL+ K+ Y + RP+ + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS ++T++ +C M+L+ FPMD Q C + + S+GYT+ +L F W + V L +P+F + + CT+ +TG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A + +++ ++E+ R G G G G+ + +NN + K ++E K+ K+ ID SR FP FL++N FYW+ Y ++
Sbjct: 32 DKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFRRRRRHMKED------------------------ETGDGRFGFPG-YGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKR-------------IDTVSRVAFPLVFLIFNIFYWITYKII 428
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 234.187 bits (596), Expect = 1.585e-70 Identity = 136/442 (30.77%), Postives = 221/442 (50.00%), Query Frame = 1
Query: 181 RIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLL-KELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVL 1503
RIR D K + + V I I + S+ M Y +++LRQ W D RL + + +S + PS+ D IW PDLFF N K H +TT N L+R+ NG VLYS ++T++ +C M+L+ FPMD Q C + + S+GYT+ +L F W + V L +P+F + + CT+ +TG +TC++A L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV +AL+E+A + +++ ++E+ R G G G G+ + +NN + K ++E K+ K+ ID SR FP FL++N FYW+ Y ++
Sbjct: 44 RIRPNFKDPKGSKNEATHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFRRRRRHMKED------------------------ETGDGRFGFPG-YGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKR-------------IDTVSRVAFPLVFLIFNIFYWITYKII 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra2 (glycine receptor alpha 2 [Source:NCBI gene;Acc:101169154]) HSP 1 Score: 233.802 bits (595), Expect = 2.060e-70 Identity = 122/334 (36.53%), Postives = 198/334 (59.28%), Query Frame = 1
Query: 88 FWKIFLEFFTVFI------LVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTL-VMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNI-VSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFA 1065
F K+ FT + LVN+ D S +S + + + + Y + RP+ + V I I + S+ M Y +++LRQ W D RL + K+ +S++ + PS+ D IW PDLFF N K H++TT N L+R+ +G VLYS +LT++ SC M+L+ FPMD Q C + + S+GYT+ +L F W + + V + L +P+F + E CT+ +TG +TC++ L RQ+G YL Y+PS+LI+++SW++FW+++DA PAR+ LG+ ++L + + ++LP+VSY+KAID+W+ C++FV AAL+E+A
Sbjct: 11 FVKVLAALFTYLMETRNCGLVNAKEHDSRSSNMSPSDFLDSLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYS-----KYPDSSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLVFEWLEYGAVQVSEGLTLPQFIMKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYA 337
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000008993.1 (SMESG000008993.1) HSP 1 Score: 962.6 bits (2487), Expect = 0.000e+0 Identity = 489/489 (100.00%), Postives = 489/489 (100.00%), Query Frame = 1
Query: 67 MMEIEIRFWKIFLEFFTVFILVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQHGSN 1533
MMEIEIRFWKIFLEFFTVFILVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFSMIKSMNSISKEKKSNNNNSNRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQHGSN
Sbjct: 1 MMEIEIRFWKIFLEFFTVFILVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFSMIKSMNSISKEKKSNNNNSNRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRYPIQHGSN 489
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000037124.1 (SMESG000037124.1) HSP 1 Score: 487.263 bits (1253), Expect = 7.960e-169 Identity = 251/456 (55.04%), Postives = 335/456 (73.46%), Query Frame = 1
Query: 169 STQERIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNE-------VLLKELDER--NKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIR 1509
S +E+I+N + YK ERP EN T+V +Y+K+LAI+SVDV +M+YSTDVYLRQ WID RL W+H+E+F+ YN+N+VSP K++IWLPDLFFRNGK GY+H+MTTPNYL+RLQPNGEVLYSQK+TM FSCQM+LQ FPMDTQ C ++IGSYGYTL++LKF WR+++ + + ++IPEF+ P ++TIDC++ S+TSTG+YTC+KA L RQLGSYLASTY+P++LI+MVSW+NFWVSIDAVPARITLGLL+LLGI+ A MS+ LPRVSYIKAIDVW+IACI+FVI AL+EFAIA+ + +++ S+ WQ DV +++ +E+ S KK + N ++ +MG P N + + S + S NE L +L E N+ R ++ KP ++ +DS ID YS+FLFPA F+LYNCFYWLYY++L+R
Sbjct: 12 SDREQIQNHIFKG--YKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARITLGLLTLLGILTQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQEL-----------FKWSKMALKKQQSINFLQMHLMGT-----PKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVR 449
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000077704.1 (SMESG000077704.1) HSP 1 Score: 465.692 bits (1197), Expect = 1.002e-160 Identity = 237/474 (50.00%), Postives = 323/474 (68.14%), Query Frame = 1
Query: 97 IFLEFFTVFILVNSTTCDISSKYLSTQER--IRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRY 1512
+ LE F + +V + + S +R IR ++ K Y K++RP E T V +Y+KILAI+SV V QM+YSTDVYLRQ W+DSRL W +L++FK YN+NIVSPSLK +WLPDLFFRNGK+GY+H MT PNYLMRL PNG +LYSQK+TM FSCQM+L+ FPMDTQ CE++IGSYGYTL+EL+F WR D+I++ ++I EF++P T DCT+ S+TSTG Y+CLKA L RQLGSY+ ST+VPSILI+MVSW+NFW+ +D+VPAR+ LGL++LLG++ AI +SSTLPRVSYIKAID+W+I CIIFVI AL+E+A+A SV+ RN S + +++V +++ E+ T+F + ++ M + D L + +N ++ K +D K+ + ++ P N S +D YSRFLFPA FL YNCFYW+Y++VL+ Y
Sbjct: 4 VCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSK--YLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARVMLGLVTLLGMLTQAIGISSTLPRVSYIKAIDIWVIWCIIFVICALLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAF------------------DRLQISHMQVHNSLDR--------DRLQFCHDLENLLIEKAIDSHKKVIK--VRPPEN--------SIVDVYSRFLFPALFLFYNCFYWVYFLVLVNY 439
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000032691.1 (SMESG000032691.1) HSP 1 Score: 451.055 bits (1159), Expect = 6.527e-155 Identity = 237/473 (50.11%), Postives = 322/473 (68.08%), Query Frame = 1
Query: 118 VFILVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEV-LLKELD--------ERNKMSRFTMKKPNNTKSKSSV-DSTIDNYSRFLFPACFLLYNCFYWLYYIVLI 1506
+F+L C+ S T+ERI +K+L Y ERP E+N T VM+++K+LAI+SV+V M+YSTD+YLRQ W+D+RLRW++L EFKH+NS++VSPSLKD +WLPDLFFRNGK+GY+H MT PNYLMRL PNGEVLYSQK+TM FSCQM+LQ +PMDTQ+CE+NIGSYGYTL++LKFYW + + + ++IPEF+ P +ET DCT S T TG Y+CLKA+ L RQLGSYL ST++P+ LI++VSW+NFWVS++AVPARITLGLL+LLGI+ A +S LPRVSYIKAIDVWLIACI+FVI AL+EFA+A++V ++ W+S+V ++R+E++ + + N M S ++NE+ +ELD N S+ + + K S + +S ID YSR+LFP+CF+ YN YW+YY++++
Sbjct: 12 IFLLAIHVGCNSCSVAGITRERIMDKILQN--YSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDARLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARITLGLLTLLGILTQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAI------------------------------------NRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 446
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000041886.1 (SMESG000041886.1) HSP 1 Score: 448.358 bits (1152), Expect = 6.957e-154 Identity = 220/433 (50.81%), Postives = 297/433 (68.59%), Query Frame = 1
Query: 214 YKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFXXXXXXXXXXXXXXXXXXXXXRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNEVLLKELDERNKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIRY 1512
Y + P +N T VM+Y+K+L+IDSV+V M YSTD+YLRQ W+D RLRW+ L++ H+NSNIV+P+LKD++WLPDLFFRNGK GY+H MT NYLMRL P GE+LYSQK+TM FSCQM+L+ FPMDTQ+CE++IGSYGYT++ELKF+WR D I + K ++IPEF++P ++T+DCT S T+TG+YTCLK + TL RQLGSYL ST++P+ LI++VSW+NFW+ +DA PAR+TLGLL+LLGI+ A ++ TLPRVSYIKAIDVW+IACI+FVI AL+E+ +A++ ++ +K W DV ++ EI M F + NL D F+N+ ++KE + + K N S DS +D YSRF+FPACF+LYN F+W YY+VL+ Y
Sbjct: 42 YTNTDLPLHSNQTRVMVYMKLLSIDSVNVSNMDYSTDLYLRQQWVDPRLRWDDLQDLNHFNSNIVTPALKDKVWLPDLFFRNGKFGYVHKMTRSNYLMRLNPKGEILYSQKITMGFSCQMDLKTFPMDTQHCEMDIGSYGYTIDELKFFWRASDPINIGKTVQIPEFNSPTKVDTLDCTSASKTTTGSYTCLKVVFTLKRQLGSYLVSTFIPNSLIVVVSWLNFWIRVDAAPARVTLGLLTLLGILTQASGITKTLPRVSYIKAIDVWMIACIMFVIGALIEYILASTAMQNRKTKQWNQDVNLVVHREIERMDRLFLKV---------------------------------NLSVVNDETFTNDFRS---MVKEKNVLKYRDKVRFMKKNRPFSVEITDSDVDRYSRFIFPACFILYNVFFWYYYLVLVNY 438 The following BLAST results are available for this feature:
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015710 ID=SMED30015710|Name=Glycine receptor subunit alpha-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1675bpback to top protein sequence of SMED30015710-orf-1 >SMED30015710-orf-1 ID=SMED30015710-orf-1|Name=SMED30015710-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=490bp MMEIEIRFWKIFLEFFTVFILVNSTTCDISSKYLSTQERIRNKLLDKIVYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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