Muscarinic acetylcholine receptor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015707 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Human
Match: CHRM3 (cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952]) HSP 1 Score: 252.677 bits (644), Expect = 3.404e-75 Identity = 193/516 (37.40%), Postives = 271/516 (52.52%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMH--GLPIKT--------------SYESSNGSRCSNNHKNHSR------ENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDA----ESLNHLVI-------------VNPN-AKEFPNQPSTSNAMVMLSHYSGSQKSE------------NKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
SF V +QL++++NYFLLSLA ADL+IG++SM L+T Y+++ W L CDLWL+IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ +T TA A+++PVTI++ILY+RIY+ET R K L + G +T SYE S +N + + R ++ ++++ SSS + NN +A S + NSA+ S + I E R+IYS + L+ ++ +++ LP S N+ +PEE +D + L++Q+ D +S + L I VN + K P + + ++ +S+ KAA+TLSAILLAF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 92 SFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLE------NSAS--SDEEDIGSE--------TRAIYSIV------LKLPGHSTILNSTKLP-----------------SSDNLQVPEE---ELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFC---DSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLC 561
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Human
Match: CHRM3 (cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952]) HSP 1 Score: 252.677 bits (644), Expect = 3.404e-75 Identity = 193/516 (37.40%), Postives = 271/516 (52.52%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMH--GLPIKT--------------SYESSNGSRCSNNHKNHSR------ENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDA----ESLNHLVI-------------VNPN-AKEFPNQPSTSNAMVMLSHYSGSQKSE------------NKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
SF V +QL++++NYFLLSLA ADL+IG++SM L+T Y+++ W L CDLWL+IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ +T TA A+++PVTI++ILY+RIY+ET R K L + G +T SYE S +N + + R ++ ++++ SSS + NN +A S + NSA+ S + I E R+IYS + L+ ++ +++ LP S N+ +PEE +D + L++Q+ D +S + L I VN + K P + + ++ +S+ KAA+TLSAILLAF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 92 SFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLE------NSAS--SDEEDIGSE--------TRAIYSIV------LKLPGHSTILNSTKLP-----------------SSDNLQVPEE---ELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFC---DSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLC 561
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Human
Match: CHRM2 (cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951]) HSP 1 Score: 213.386 bits (542), Expect = 1.057e-61 Identity = 169/480 (35.21%), Postives = 234/480 (48.75%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKK---MHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLA----FFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
S V R L++++NYFL SLA ADL+IG+ SM LYT Y V+G WPL +CDLWL++DY +SNASV NLLIIS DRY VT+PLTY +KRT+K + I AW++S +LW P I W I G R V+ ECYIQF + +T TA A+++PV I+++LY+ I R + R K KK + P+ S + +NN+ S + N I+ NGK P N G +E ESS S ASN R + I + N S S+G+ N + IR + + SC + V+ + Q + +V ++ +K K ++ +LA F ITW PYN+ +IN F I TV+ +GYWLCY+NST+NP YALCN TF+KTF +L C I +T+
Sbjct: 47 SIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS-NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQ----------NGKA-------PRDPVTENCVQG--------EEKESSN----DSTSVSAVASNMR---------------DDEITQDENTVST-----SLGHSK-------DENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC---APCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Human
Match: CHRM2 (cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951]) HSP 1 Score: 213.386 bits (542), Expect = 1.057e-61 Identity = 169/480 (35.21%), Postives = 234/480 (48.75%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKK---MHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLA----FFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
S V R L++++NYFL SLA ADL+IG+ SM LYT Y V+G WPL +CDLWL++DY +SNASV NLLIIS DRY VT+PLTY +KRT+K + I AW++S +LW P I W I G R V+ ECYIQF + +T TA A+++PV I+++LY+ I R + R K KK + P+ S + +NN+ S + N I+ NGK P N G +E ESS S ASN R + I + N S S+G+ N + IR + + SC + V+ + Q + +V ++ +K K ++ +LA F ITW PYN+ +IN F I TV+ +GYWLCY+NST+NP YALCN TF+KTF +L C I +T+
Sbjct: 47 SIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS-NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQ----------NGKA-------PRDPVTENCVQG--------EEKESSN----DSTSVSAVASNMR---------------DDEITQDENTVST-----SLGHSK-------DENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC---APCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Human
Match: CHRM2 (cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951]) HSP 1 Score: 213.386 bits (542), Expect = 1.057e-61 Identity = 169/480 (35.21%), Postives = 234/480 (48.75%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKK---MHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLA----FFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
S V R L++++NYFL SLA ADL+IG+ SM LYT Y V+G WPL +CDLWL++DY +SNASV NLLIIS DRY VT+PLTY +KRT+K + I AW++S +LW P I W I G R V+ ECYIQF + +T TA A+++PV I+++LY+ I R + R K KK + P+ S + +NN+ S + N I+ NGK P N G +E ESS S ASN R + I + N S S+G+ N + IR + + SC + V+ + Q + +V ++ +K K ++ +LA F ITW PYN+ +IN F I TV+ +GYWLCY+NST+NP YALCN TF+KTF +L C I +T+
Sbjct: 47 SIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS-NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQ----------NGKA-------PRDPVTENCVQG--------EEKESSN----DSTSVSAVASNMR---------------DDEITQDENTVST-----SLGHSK-------DENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC---APCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Celegans
Match: gar-3 (Muscarinic acetylcholine receptor gar-3 [Source:UniProtKB/Swiss-Prot;Acc:Q9U7D5]) HSP 1 Score: 179.104 bits (453), Expect = 1.365e-48 Identity = 94/180 (52.22%), Postives = 128/180 (71.11%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
SF +++QL++ISNYFL SLAVAD+ IG++S+P++T Y + +W L Y +C WL IDY MSNASV NLL+IS DRY SVTRPL+YR +RT+KK I +IIS +LW P I WP I+GK +P C +QF+Q++ +T+ TA A+++PVTI+ ILY R+Y ET RQK K+
Sbjct: 89 SFKIDKQLQTISNYFLFSLAVADIAIGVISIPMFTYYTAIQKWDLGYTMCQFWLCIDYLMSNASVLNLLLISFDRYFSVTRPLSYRPRRTTKKALTMIACTYIISLILWPPWIISWPYIEGKFTAEPGTCVVQFLQTNPYVTVGTAVAAFYLPVTIMCILYTRVYWETQKRQKEFGKLQA 268 HSP 2 Score: 93.5893 bits (231), Expect = 9.465e-20 Identity = 45/90 (50.00%), Postives = 57/90 (63.33%), Query Frame = 2
Query: 1409 QKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRST 1678
+K E+KAAKTLSAIL AF TWTPYN+ AF+ + ++ Y+LCY+NST+NPL YALCN FR T++ IL C R T
Sbjct: 490 RKQESKAAKTLSAILCAFIATWTPYNLIVCWEAFFP---NTVPNVLWTFSYFLCYINSTINPLCYALCNARFRHTYMRILRCKFKAERPT 576
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Celegans
Match: gar-3 (Muscarinic acetylcholine receptor gar-3 [Source:UniProtKB/Swiss-Prot;Acc:Q9U7D5]) HSP 1 Score: 179.104 bits (453), Expect = 1.365e-48 Identity = 94/180 (52.22%), Postives = 128/180 (71.11%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
SF +++QL++ISNYFL SLAVAD+ IG++S+P++T Y + +W L Y +C WL IDY MSNASV NLL+IS DRY SVTRPL+YR +RT+KK I +IIS +LW P I WP I+GK +P C +QF+Q++ +T+ TA A+++PVTI+ ILY R+Y ET RQK K+
Sbjct: 89 SFKIDKQLQTISNYFLFSLAVADIAIGVISIPMFTYYTAIQKWDLGYTMCQFWLCIDYLMSNASVLNLLLISFDRYFSVTRPLSYRPRRTTKKALTMIACTYIISLILWPPWIISWPYIEGKFTAEPGTCVVQFLQTNPYVTVGTAVAAFYLPVTIMCILYTRVYWETQKRQKEFGKLQA 268 HSP 2 Score: 93.5893 bits (231), Expect = 9.465e-20 Identity = 45/90 (50.00%), Postives = 57/90 (63.33%), Query Frame = 2
Query: 1409 QKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRST 1678
+K E+KAAKTLSAIL AF TWTPYN+ AF+ + ++ Y+LCY+NST+NPL YALCN FR T++ IL C R T
Sbjct: 490 RKQESKAAKTLSAILCAFIATWTPYNLIVCWEAFFP---NTVPNVLWTFSYFLCYINSTINPLCYALCNARFRHTYMRILRCKFKAERPT 576
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Celegans
Match: gar-3 (Muscarinic acetylcholine receptor gar-3 [Source:UniProtKB/Swiss-Prot;Acc:Q9U7D5]) HSP 1 Score: 179.104 bits (453), Expect = 1.931e-48 Identity = 94/180 (52.22%), Postives = 128/180 (71.11%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
SF +++QL++ISNYFL SLAVAD+ IG++S+P++T Y + +W L Y +C WL IDY MSNASV NLL+IS DRY SVTRPL+YR +RT+KK I +IIS +LW P I WP I+GK +P C +QF+Q++ +T+ TA A+++PVTI+ ILY R+Y ET RQK K+
Sbjct: 89 SFKIDKQLQTISNYFLFSLAVADIAIGVISIPMFTYYTAIQKWDLGYTMCQFWLCIDYLMSNASVLNLLLISFDRYFSVTRPLSYRPRRTTKKALTMIACTYIISLILWPPWIISWPYIEGKFTAEPGTCVVQFLQTNPYVTVGTAVAAFYLPVTIMCILYTRVYWETQKRQKEFGKLQA 268 HSP 2 Score: 93.5893 bits (231), Expect = 9.459e-20 Identity = 45/90 (50.00%), Postives = 57/90 (63.33%), Query Frame = 2
Query: 1409 QKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRST 1678
+K E+KAAKTLSAIL AF TWTPYN+ AF+ + ++ Y+LCY+NST+NPL YALCN FR T++ IL C R T
Sbjct: 516 RKQESKAAKTLSAILCAFIATWTPYNLIVCWEAFFP---NTVPNVLWTFSYFLCYINSTINPLCYALCNARFRHTYMRILRCKFKAERPT 602
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Celegans
Match: dop-4 (Dopamine receptor 4 [Source:UniProtKB/Swiss-Prot;Acc:Q18775]) HSP 1 Score: 100.908 bits (250), Expect = 2.671e-22 Identity = 115/465 (24.73%), Postives = 213/465 (45.81%), Query Frame = 2
Query: 275 ERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGE-WPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKT-SYESSNGSRCSNNHKN-HSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATG-LSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNP-NAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
++ LR+ + Y ++SLA+ADL++G++ MP+ + + + W +CD++ ++D S AS+ NL +IS+DRY + P+ YR K + +++ + I W++SA+L P I W + +C S + ++ ++++IP+ +I Y ++Y K ++ + IKT S + NG + + ++ S EN +LR GK S++S ++ F +T L Q S + + ++ L LR ++ DS S + F RN T + ++ ++ P+ + + N + +V+ +P + + N S M+ H E +AA+TLS ++ AF + WTP+ +FT + AF T++ W +LNS +NPL+Y+ + FR+ F ILTC
Sbjct: 70 KKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEIANHTWLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVLSAILSFPGIIWWRTSSPHLYEDQSQC---LFTDSKMYVSFSSLVSFYIPLFLILFAYGKVYIIATRHSKGMR----MGIKTVSIKKRNGKKSNTETESILSSENE--------PTLRIHFGRGKQ--SSSSLRNSRFHARESTRLLLKQVSCKSLNDRGEHNNNNTVRQPL------LRGTEGCHSDSISRSSQRNFRGRNVTIGSNCSSTLLQVDQPDRMSLSSN-----------------------SQMVMTSPLSTRRKLNVREKSRQMMRYVH-------EQRAARTLSIVVGAFILCWTPFFVFTPLTAFCE-SCFSNKETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQILTC 480
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Celegans
Match: gar-2 (Muscarinic acetylcholine receptor gar-2 [Source:UniProtKB/Swiss-Prot;Acc:Q09388]) HSP 1 Score: 96.2857 bits (238), Expect = 3.202e-22 Identity = 73/210 (34.76%), Postives = 119/210 (56.67%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTG-YLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGK-RHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRET-NLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENP 883
S+ +++ +R +NYF+ SLA++DL+IGL +P+YT YL EW +CDLWLSIDY + AS+ +L I++DRY SV +P TYR RT +V + I W++ ++L++ I+ + G R +K ECY+QF+ + L + Y+ + ++ LY+ IYR L K +K L + T S +++ N S ++P
Sbjct: 29 SYYLDKNIRQPTNYFIFSLAISDLLIGLEGIPVYTAFYLNNNEWIWGDVLCDLWLSIDYIVCLASIYTVLGITVDRYYSVKKPATYRNWRTPGRVVLIIIFIWLVPSILFSVSIFGYGTFTGTGRILKETECYVQFMT-NPYLNMGMYISYYWTTLFVMLYLYWGIYRAAKKLALKSDQKTKRLALLTEMRRPEVSVRTSDAGNSSSDSP 237
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Fly
Match: mAChR-A (gene:FBgn0000037 transcript:FBtr0072368) HSP 1 Score: 191.43 bits (485), Expect = 8.482e-52 Identity = 130/277 (46.93%), Postives = 169/277 (61.01%), Query Frame = 2
Query: 68 ALKEILMITEKLSNNDQYYFTSVNLTNRTGSAYAKG--LSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQN 892
AL E L T D Y N TN T KG SL +++ + I+ +TV GN++V+ SF +++QL++ISNYFL SLA+AD IG +SMPL+ ++G WPL +CD WL++DY SNASV NLLIIS DRY SVTRPLTYR KRT+ + ++ IG AW IS LLW P IY WP I+GKR V ECYIQFI+++ +T TA A++ PVTI+ LY+RI+RET RQK L + G + S+ N S EN N
Sbjct: 61 ALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQA-----------GKKDSSKRSNSSDENTVVN 326 HSP 2 Score: 100.908 bits (250), Expect = 7.237e-22 Identity = 48/85 (56.47%), Postives = 63/85 (74.12%), Query Frame = 2
Query: 1400 SGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
S ++ E+KAAKTLSAILL+F ITWTPYNI +I T + I T +++ Y LCY+NST+NP+ YALCN TFR+T++ ILTC
Sbjct: 706 SQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTC-SDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTC 789
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Fly
Match: mAChR-A (gene:FBgn0000037 transcript:FBtr0072367) HSP 1 Score: 191.43 bits (485), Expect = 9.005e-52 Identity = 130/277 (46.93%), Postives = 169/277 (61.01%), Query Frame = 2
Query: 68 ALKEILMITEKLSNNDQYYFTSVNLTNRTGSAYAKG--LSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQN 892
AL E L T D Y N TN T KG SL +++ + I+ +TV GN++V+ SF +++QL++ISNYFL SLA+AD IG +SMPL+ ++G WPL +CD WL++DY SNASV NLLIIS DRY SVTRPLTYR KRT+ + ++ IG AW IS LLW P IY WP I+GKR V ECYIQFI+++ +T TA A++ PVTI+ LY+RI+RET RQK L + G + S+ N S EN N
Sbjct: 61 ALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQA-----------GKKDSSKRSNSSDENTVVN 326 HSP 2 Score: 100.908 bits (250), Expect = 8.228e-22 Identity = 48/85 (56.47%), Postives = 63/85 (74.12%), Query Frame = 2
Query: 1400 SGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
S ++ E+KAAKTLSAILL+F ITWTPYNI +I T + I T +++ Y LCY+NST+NP+ YALCN TFR+T++ ILTC
Sbjct: 689 SQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTC-SDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTC 772
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Fly
Match: mAChR-B (gene:FBgn0037546 transcript:FBtr0344726) HSP 1 Score: 116.701 bits (291), Expect = 6.471e-27 Identity = 65/136 (47.79%), Postives = 88/136 (64.71%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQ 670
+FIV+R +R SNYF+ SLA D++IG VSMP YT Y++ G W L +CDLWLS+DYT+ S +L+I+IDRYCSV YR RT +V + I WII ALL+ I+ W GKR + P +C +QF++
Sbjct: 157 AFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTGKRDLLPGQCAVQFLK 292 HSP 2 Score: 65.855 bits (159), Expect = 7.177e-11 Identity = 40/100 (40.00%), Postives = 54/100 (54.00%), Query Frame = 2
Query: 1367 TSNAMVMLSHYSGSQKS--ENKAAK---TLSAILLAFFITWTPYNIFTVINAFYTVETQP-IGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAIL 1648
+ A+ ++ G QKS EN+A K T+S IL F WTPY++ ++ F P I +Y Y+LCY NS +NP YAL N F+KTF IL
Sbjct: 651 SKKALPLILGVGGRQKSKSENRARKAFRTISFILGCFVACWTPYHVLALVEGF--CRHPPCINEHLYMFSYFLCYANSPMNPFCYALANQQFKKTFTRIL 748
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Fly
Match: mAChR-B (gene:FBgn0037546 transcript:FBtr0081789) HSP 1 Score: 117.087 bits (292), Expect = 7.805e-27 Identity = 65/136 (47.79%), Postives = 88/136 (64.71%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQ 670
+FIV+R +R SNYF+ SLA D++IG VSMP YT Y++ G W L +CDLWLS+DYT+ S +L+I+IDRYCSV YR RT +V + I WII ALL+ I+ W GKR + P +C +QF++
Sbjct: 157 AFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTGKRDLLPGQCAVQFLK 292 HSP 2 Score: 66.6254 bits (161), Expect = 4.619e-11 Identity = 40/100 (40.00%), Postives = 54/100 (54.00%), Query Frame = 2
Query: 1367 TSNAMVMLSHYSGSQKS--ENKAAK---TLSAILLAFFITWTPYNIFTVINAFYTVETQP-IGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAIL 1648
+ A+ ++ G QKS EN+A K T+S IL F WTPY++ ++ F P I +Y Y+LCY NS +NP YAL N F+KTF IL
Sbjct: 915 SKKALPLILGVGGRQKSKSENRARKAFRTISFILGCFVACWTPYHVLALVEGF--CRHPPCINEHLYMFSYFLCYANSPMNPFCYALANQQFKKTFTRIL 1012
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Fly
Match: TyrR (gene:FBgn0038542 transcript:FBtr0344474) HSP 1 Score: 99.3673 bits (246), Expect = 2.113e-21 Identity = 43/94 (45.74%), Postives = 67/94 (71.28%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKV 544
+ + R+LR+I+N F++SLAVADL++G+ MP ++G W L + +CD+W+S+D + AS+ +L IS+DRY +VTRPLTY KR SK++
Sbjct: 140 AILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAVHLIGSWQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRL 233 HSP 2 Score: 49.6766 bits (117), Expect = 7.883e-6 Identity = 34/89 (38.20%), Postives = 44/89 (49.44%), Query Frame = 2
Query: 1388 LSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
LS+ S K ENK +TLS ++ F W P+ I +I F E Q L WL + NS +NP +YA +V FR F LTC
Sbjct: 525 LSNRITSLKKENKTTQTLSIVVGGFIACWLPFFINYLITPFLA-EHQASQMLAKAL-TWLGWFNSAINPFIYAFYSVDFRAAFWR-LTC 610
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Zebrafish
Match: chrm5a (cholinergic receptor, muscarinic 5a [Source:ZFIN;Acc:ZDB-GENE-080723-32]) HSP 1 Score: 248.44 bits (633), Expect = 6.898e-75 Identity = 180/479 (37.58%), Postives = 257/479 (53.65%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKS---CDAESLN---HLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ I IG+AW++S +LW P I W GKR V ++C IQF + + YF PV++++ILY RIY+ET R K L ++ G+ N+ N S + Q + S G ++S S N+A L Q + + SS+ E + E + R + +KS+S + + P P+ + T K V K +P + SP+++ + ++ + AES+N P Q + MV++ E KAA+TLSAILLAF +TWTPYNI +I+ F + I ++++LGYWLCY+NSTVNP+ YALCN TF+KTF +L C K R+ +
Sbjct: 49 SFKVNSQLKTVNNYYLLSLAFADLIIGVFSMNLYTSYILMGYWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPPILCWQYFVGKRTVPERQCQIQFFSEPVITFGTAIAAFYF-PVSVMTILYCRIYKETERRTKDLAELQGI---------------NSSTNSSGDAQPQKI---------RSCFGCKHVSNTSRTQALSHTNAAKTLDDQLTNFNSYASSEEEDRSGNFQE----SCRHQENKSESYEEENFFPTPVKASPTKTKKCV------------SYKFKPKDV-SPLKNTNGDAKPGASSFSSAESVNAPSSSSSSKPIDGTLKCQITKRKRMVLI--------KEKKAAQTLSAILLAFILTWTPYNIMVLISTFC---SDCIPLSLWHLGYWLCYVNSTVNPMCYALCNKTFQKTFRMLLLCQWRKQRAEE 474
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Zebrafish
Match: chrm5b (cholinergic receptor, muscarinic 5b [Source:ZFIN;Acc:ZDB-GENE-041001-169]) HSP 1 Score: 246.514 bits (628), Expect = 1.850e-74 Identity = 185/484 (38.22%), Postives = 265/484 (54.75%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPF--RPNSATGLSTQTSIYQEG----ESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNH-----LVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ I IG+AW+IS +LW P I W G+R V +C IQF S ++T TA A+++PV+I++ILY +IY+ET R K L ++ G P S +S +G + K R F+N K+ + S SS+ ++ ++ + +S + T L++ TS + ES+ E ++ +S + + Y S+ L + KCS N K +P D + + +S+R + D S P Q + MV++ E KAA+TLSAILLAF +TWTPYNI +I+ F + I T+++ LGYWLCY+NSTVNP+ YALCN TF+KTF ++ C K R +
Sbjct: 3 SFKVNSQLKTVNNYYLLSLAFADLIIGVFSMNLYTCYILMGYWSLGNTACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGMAWLISFILWAPPILCWQYFVGERKVPLDQCQIQFF-SEPIITFGTAIAAFYVPVSIMTILYCKIYKETEKRTKNLAELQGYP---SLDSQDGPKV---RKPILRCFSFKN--KRDGTQASWSSSNQSYVTRTTLQSDDLWTKSEQVTTLNSYTSSEDDDRSVSESTPRESFKNQEPPVSKNGQLVCYEDSKYLS------------------DLAKCSQTNNKKCLSYKFKPIISDITVLQGNSESERANPDQSSDQQAPSSTSSSTKPEDPNLKIQMTKRKRMVLI--------KEKKAAQTLSAILLAFLLTWTPYNIMVLISTFC---SNCIPTSLWQLGYWLCYVNSTVNPMCYALCNKTFQKTFWMLILCKWKKNRGEE 448
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Zebrafish
Match: chrm5b (cholinergic receptor, muscarinic 5b [Source:ZFIN;Acc:ZDB-GENE-041001-169]) HSP 1 Score: 246.899 bits (629), Expect = 3.988e-74 Identity = 183/480 (38.12%), Postives = 266/480 (55.42%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPF--RPNSATGLSTQTSIYQEG----ESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQK-SENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ I IG+AW+IS +LW P I W G+R V +C IQF ++T TA A+++PV+I++ILY +IY+ET R K L ++ G P S +S +G + K R F+N K+ + S SS+ ++ ++ + +S + T L++ TS + ES+ E ++ +S + + Y S+ L + KCS N K +P D + + +S+R + D S P++ +P N + ++ E KAA+TLSAILLAF +TWTPYNI +I+ F + I T+++ LGYWLCY+NSTVNP+ YALCN TF+KTF ++ C K R +
Sbjct: 51 SFKVNSQLKTVNNYYLLSLAFADLIIGVFSMNLYTCYILMGYWSLGNTACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGMAWLISFILWAPPILCWQYFVGERKVPLDQCQIQFFS-EPIITFGTAIAAFYVPVSIMTILYCKIYKETEKRTKNLAELQGYP---SLDSQDGPKV---RKPILRCFSFKN--KRDGTQASWSSSNQSYVTRTTLQSDDLWTKSEQVTTLNSYTSSEDDDRSVSESTPRESFKNQEPPVSKNGQLVCYEDSKYL------------------SDLAKCSQTNNKKCLSYKFKPIISDITVLQGNSESERANPDQSSDQQ----APSSTSSSTKPEDPNLKIQMTKRKRMVLIKEKKAAQTLSAILLAFLLTWTPYNIMVLISTFC---SNCIPTSLWQLGYWLCYVNSTVNPMCYALCNKTFQKTFWMLILCKWKKNRGEE 496
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Zebrafish
Match: chrm2a (cholinergic receptor, muscarinic 2a [Source:ZFIN;Acc:ZDB-GENE-030314-1]) HSP 1 Score: 238.424 bits (607), Expect = 4.920e-71 Identity = 171/477 (35.85%), Postives = 250/477 (52.41%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDT-SKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPS---TSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
S V R L++++NYFL SLA ADL+IGL SM LYT Y+V+G WPL +CDLWL++DY +SNASV NLLIIS DRY VT+PL+Y +KRT+K + I AW++S +LW P I W I G R V KECYIQF + +T TA A+++PV I+ +LY+++ R + R +KK + P + + ++ SN + +S P N N + G+ ++ ++ H + + ST + GE+ + I +E S++ + P ND+ + T ++ G + + I+ ++ KS + C A S N V + P A E N + E K +T+ AIL+AF TWTPYN+ +IN F + I TV+ +GYWLCY+NST+NP YALCN+TF+KTF +L C IRST+
Sbjct: 55 SIKVNRSLQTVNNYFLFSLACADLIIGLCSMNLYTVYIVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLSYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEKECYIQFFS-NAAVTFGTAIAAFYLPVIIMMVLYWQVSRASKSR---VKKDNRKPSGGNLDVAS----SNQIRENSANKPTNN-----NLTAEETDRGQTQLTDDTINQHDAKLQNGKAPSTAS-----GEAEEAGQANCIPAEEKESSNDSTSGSGAVTNQKEEAAPPSSAAANDSQTSTRHRAKAGGSKL------------TCIKIIT-KSPKGDCYAPS-NATVEIVP-AVERQNHVARKIVKMTKQPPKKKKAPSSREKKVTRTIMAILVAFVATWTPYNVMVLINTFC---SSCIPNTVWTIGYWLCYINSTINPACYALCNITFKKTFKQLLLCQYKNIRSTR 495
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Zebrafish
Match: chrm2a (cholinergic receptor, muscarinic 2a [Source:ZFIN;Acc:ZDB-GENE-030314-1]) HSP 1 Score: 238.424 bits (607), Expect = 4.920e-71 Identity = 171/477 (35.85%), Postives = 250/477 (52.41%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDT-SKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPS---TSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
S V R L++++NYFL SLA ADL+IGL SM LYT Y+V+G WPL +CDLWL++DY +SNASV NLLIIS DRY VT+PL+Y +KRT+K + I AW++S +LW P I W I G R V KECYIQF + +T TA A+++PV I+ +LY+++ R + R +KK + P + + ++ SN + +S P N N + G+ ++ ++ H + + ST + GE+ + I +E S++ + P ND+ + T ++ G + + I+ ++ KS + C A S N V + P A E N + E K +T+ AIL+AF TWTPYN+ +IN F + I TV+ +GYWLCY+NST+NP YALCN+TF+KTF +L C IRST+
Sbjct: 55 SIKVNRSLQTVNNYFLFSLACADLIIGLCSMNLYTVYIVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLSYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEKECYIQFFS-NAAVTFGTAIAAFYLPVIIMMVLYWQVSRASKSR---VKKDNRKPSGGNLDVAS----SNQIRENSANKPTNN-----NLTAEETDRGQTQLTDDTINQHDAKLQNGKAPSTAS-----GEAEEAGQANCIPAEEKESSNDSTSGSGAVTNQKEEAAPPSSAAANDSQTSTRHRAKAGGSKL------------TCIKIIT-KSPKGDCYAPS-NATVEIVP-AVERQNHVARKIVKMTKQPPKKKKAPSSREKKVTRTIMAILVAFVATWTPYNVMVLINTFC---SSCIPNTVWTIGYWLCYINSTINPACYALCNITFKKTFKQLLLCQYKNIRSTR 495
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Xenopus
Match: ENSXETT00000048394.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:5:59937956:59939943:1 gene:ENSXETG00000020181.1 transcript:ENSXETT00000048394.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 246.899 bits (629), Expect = 1.915e-73 Identity = 192/495 (38.79%), Postives = 263/495 (53.13%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSS----------SSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYS---ELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCS-------IGNINIPEEVKIRPNRID---SPIRHLSLKSQRKSCDAE--SLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIR 1672
+F V +QL++++NYFLLSLA ADL+IG++SM L+T Y+++ W + CDLWL IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ I IG+AWIIS +LW P I W GKR V EC+IQF + ++T TA A+++PV+I++ILY+RIY+ET R K L + K E S + N K +S Q IK + R S + K I + S + N A + E ++ E R+IYS +L N L +KSQS +N+ +TSK + K N+N ++ + I SP S+ + K+ S + + A + NQ + M ++ E KAA+TLSAILLAF ITW PYNI ++N F I +NLGYWLCY+NST+NP+ YALCN TFR TF +L C KI+
Sbjct: 73 AFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMDHWIMGSLACDLWLMIDYVASNASVMNLLVISFDRYFSITRPLTYRTKRTTKRAGIMIGLAWIISFILWAPAILFWQYFVGKRTVPSDECFIQFF-TEPIITFGTAIAAFYLPVSIMTILYWRIYKETEKRTKELAGLQASGGK--LEVPGLSHRTGNAKGNSNYK-IQRNIKFSSRTRYSWCTFRFKPKMCKSDKKQIEQDQSSSESWNHNDANASLDNSGTSDEEDAP--ENPRAIYSIVLKLPGHNSVLSKTKSQS------------SNQGNTSKGMQKSGPQPKELRFKNLNSQRNLQNKDESISVSLSPQTDHSMNTSSKTTAPLPISFKEIALAKRFAAKTRNQITKRKRMSLI--------KEKKAAQTLSAILLAFIITWAPYNIMVLVNTFC---ESCIPRIYWNLGYWLCYINSTINPICYALCNKTFRTTFKILLLCQCDKIK 538
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Xenopus
Match: slitrk3 (SLIT and NTRK like family member 3 [Source:Xenbase;Acc:XB-GENE-964617]) HSP 1 Score: 175.637 bits (444), Expect = 1.952e-47 Identity = 114/224 (50.89%), Postives = 155/224 (69.20%), Query Frame = 2
Query: 131 SVNLTNRTGSAYAKGLSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
S +L N G+ K SL E+I + + IV +IT+VGN+LV+ SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ + IG+AW IS +LW P I W G R V P+EC IQF+ ++T TA A+++PV++++ILY RIY+ET R K L ++ G
Sbjct: 5 STSLNNSNGTVPLKAHSLWEVITIATVSAIVSLITIVGNILVMVSFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTSYILIGHWSLGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGLMIGLAWFISFILWAPAILCWQYFVGGRTVPPEECQIQFL-YEPIITFGTAIAAFYLPVSVMTILYCRIYKETEKRTKDLAELQG 227 HSP 2 Score: 104.76 bits (260), Expect = 4.526e-23 Identity = 50/83 (60.24%), Postives = 63/83 (75.90%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
E KAA+TLSAILLAF ITWTPYNI +++ F + I +++++LGYWLCY+NSTVNP+ YALCN TFRKTF +L C K
Sbjct: 425 ERKAAQTLSAILLAFIITWTPYNIMVLVSTFCS---DCIPSSLWHLGYWLCYVNSTVNPICYALCNKTFRKTFKMLLLCRWRK 504
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Xenopus
Match: CHRM1 (cholinergic receptor, muscarinic 1 [Source:NCBI gene;Acc:100490434]) HSP 1 Score: 169.474 bits (428), Expect = 3.722e-45 Identity = 98/180 (54.44%), Postives = 128/180 (71.11%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
+F V L++++NYFLLSLA AD++IG +SM LYT Y+V+G W L CDLWL++DY SNASV NLLIIS DRY S+TRPLTYR KRT ++ +I IG+AW IS +LW P I W I G+R V+ +CYIQF ++T TA A+++PVTI+ ILY+R+YRET R K L + G
Sbjct: 71 AFKVNSDLKTVNNYFLLSLACADIIIGALSMNLYTTYIVMGRWALGPVSCDLWLALDYVASNASVMNLLIISFDRYFSITRPLTYRAKRTPRRAAIMIGMAWFISFVLWAPAIIFWQYIVGERTVEATDCYIQFFS-QPIITFGTAIAAFYLPVTIMIILYWRVYRETENRSKELAGLQG 249 HSP 2 Score: 100.523 bits (249), Expect = 9.133e-22 Identity = 50/96 (52.08%), Postives = 65/96 (67.71%), Query Frame = 2
Query: 1394 HYSGSQKS-----ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
++ G +KS E KAAKTLSAILLAF +TWTPYNI +++ F + ++ LGYWLCY+NSTVNP+ YALCN +FR+TF +L C K
Sbjct: 411 NHHGKRKSNSLIKEKKAAKTLSAILLAFILTWTPYNIMVLVSTFCP---DCVPKKLWELGYWLCYVNSTVNPMCYALCNRSFRRTFKMLLLCRWDK 503
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Xenopus
Match: CHRM2 (cholinergic receptor, muscarinic 2 [Source:NCBI gene;Acc:100485603]) HSP 1 Score: 159.458 bits (402), Expect = 5.640e-42 Identity = 90/177 (50.85%), Postives = 121/177 (68.36%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKK 793
S V R L++++NYFL SLA ADL+IG+ SM LYT Y V+G WP+ +CDLWL++DY +SNASV NLLIIS DRY VT+PLTY ++RT+K + I AW++S +LW P I W I G R V ECYIQF + +T TA A+++PV I+++LY++I R + R K KK
Sbjct: 50 SIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPIGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVRRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEGECYIQFFS-NAAVTFGTAIAAFYLPVIIMTVLYWQISRASKSRIKKGKK 225 HSP 2 Score: 99.7525 bits (247), Expect = 1.365e-21 Identity = 47/88 (53.41%), Postives = 59/88 (67.05%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
E K +T+ AILLAF ITWTPYN+ +IN F V + TV+ +GYWLCY+NST+NP YALCN TF+KTF +L C I S +
Sbjct: 386 EKKVTRTILAILLAFIITWTPYNVMVLINTFCAV---CVPNTVWTIGYWLCYINSTINPACYALCNTTFKKTFKHLLMCQYKNIGSAR 470
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Xenopus
Match: ENSXETT00000024537.1 (muscarinic acetylcholine receptor M3-like [Source:NCBI gene;Acc:101730815]) HSP 1 Score: 119.013 bits (297), Expect = 1.431e-28 Identity = 73/131 (55.73%), Postives = 92/131 (70.23%), Query Frame = 2
Query: 410 CDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
CDLWL IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ I IG+AWIIS +LW P I W GKR V EC+IQF + ++T TA A+++PV+I++ILY+RIY+ET R K L +
Sbjct: 110 CDLWLMIDYVASNASVMNLLVISSDRYFSITRPLTYRTKRTTKRAGIMIGLAWIISFILWAPAILFWQYFVGKRTVPSDECFIQFF-TEPIITFGTAIAAFYLPVSIMTILYWRIYKETEKRTKELAGLQA 239
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Mouse
Match: Chrm3 (cholinergic receptor, muscarinic 3, cardiac [Source:MGI Symbol;Acc:MGI:88398]) HSP 1 Score: 179.104 bits (453), Expect = 2.997e-48 Identity = 98/180 (54.44%), Postives = 130/180 (72.22%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
+F V +QL++++NYFLLSLA ADL+IG++SM L+T Y+++ W L CDLWLSIDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ +T TA A+++PVTI++ILY+RIY+ET R K L +
Sbjct: 91 AFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQA 269 HSP 2 Score: 105.145 bits (261), Expect = 3.128e-23 Identity = 51/79 (64.56%), Postives = 58/79 (73.42%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
E KAA+TLSAILLAF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 485 EKKAAQTLSAILLAFIITWTPYNIMVLVNTFCD---SCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLC 560
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Mouse
Match: Chrm3 (cholinergic receptor, muscarinic 3, cardiac [Source:MGI Symbol;Acc:MGI:88398]) HSP 1 Score: 179.104 bits (453), Expect = 2.997e-48 Identity = 98/180 (54.44%), Postives = 130/180 (72.22%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
+F V +QL++++NYFLLSLA ADL+IG++SM L+T Y+++ W L CDLWLSIDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ +T TA A+++PVTI++ILY+RIY+ET R K L +
Sbjct: 91 AFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQA 269 HSP 2 Score: 105.145 bits (261), Expect = 3.128e-23 Identity = 51/79 (64.56%), Postives = 58/79 (73.42%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
E KAA+TLSAILLAF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 485 EKKAAQTLSAILLAFIITWTPYNIMVLVNTFCD---SCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLC 560
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Mouse
Match: Chrm5 (cholinergic receptor, muscarinic 5 [Source:MGI Symbol;Acc:MGI:109248]) HSP 1 Score: 174.096 bits (440), Expect = 7.869e-47 Identity = 99/180 (55.00%), Postives = 128/180 (71.11%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ I IG+AW++S +LW P I W + GKR V P EC IQF+ +T TA A++IPV++++ILY RIYRET R K L + G
Sbjct: 54 SFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWVLGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPAILCWQYLVGKRTVPPDECQIQFLS-EPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQG 232 HSP 2 Score: 107.842 bits (268), Expect = 3.220e-24 Identity = 58/113 (51.33%), Postives = 72/113 (63.72%), Query Frame = 2
Query: 1349 FP--NQPSTSNAMVMLSHYSGSQK-----SENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
FP PST LSH +K E KAA+TLSAILLAF ITWTPYNI +++ F + + T+++LGYWLCY+NST+NP+ YALCN TFRKTF +L C K
Sbjct: 407 FPVSKDPSTKGLDPHLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCD---KCVPVTLWHLGYWLCYVNSTINPICYALCNRTFRKTFKLLLLCRWKK 516
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Mouse
Match: Chrm1 (cholinergic receptor, muscarinic 1, CNS [Source:MGI Symbol;Acc:MGI:88396]) HSP 1 Score: 166.392 bits (420), Expect = 1.026e-44 Identity = 94/180 (52.22%), Postives = 128/180 (71.11%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
SF V +L++++NYFLLSLA ADL+IG SM LYT YL++G W L CDLWL++DY SNASV NLL+IS DRY SVTRPL+YR KRT ++ ++ IG+AW++S +LW P I W + G+R V +CYIQF+ ++T TA A+++PVT++ LY+RIYRET R + L + G
Sbjct: 49 SFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLS-QPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQG 227 HSP 2 Score: 100.908 bits (250), Expect = 4.012e-22 Identity = 48/85 (56.47%), Postives = 59/85 (69.41%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIR 1672
E KAA+TLSAILLAF +TWTPYNI +++ F + T++ LGYWLCY+NSTVNP+ YALCN FR TF +L C K R
Sbjct: 360 EKKAARTLSAILLAFILTWTPYNIMVLVSTFCK---DCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRR 441
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Mouse
Match: Chrm1 (cholinergic receptor, muscarinic 1, CNS [Source:MGI Symbol;Acc:MGI:88396]) HSP 1 Score: 166.392 bits (420), Expect = 1.026e-44 Identity = 94/180 (52.22%), Postives = 128/180 (71.11%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
SF V +L++++NYFLLSLA ADL+IG SM LYT YL++G W L CDLWL++DY SNASV NLL+IS DRY SVTRPL+YR KRT ++ ++ IG+AW++S +LW P I W + G+R V +CYIQF+ ++T TA A+++PVT++ LY+RIYRET R + L + G
Sbjct: 49 SFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLS-QPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQG 227 HSP 2 Score: 100.908 bits (250), Expect = 4.012e-22 Identity = 48/85 (56.47%), Postives = 59/85 (69.41%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIR 1672
E KAA+TLSAILLAF +TWTPYNI +++ F + T++ LGYWLCY+NSTVNP+ YALCN FR TF +L C K R
Sbjct: 360 EKKAARTLSAILLAFILTWTPYNIMVLVSTFCK---DCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRR 441
BLAST of Muscarinic acetylcholine receptor vs. UniProt/SwissProt
Match: sp|Q5IS98|ACM5_SAIBB (Muscarinic acetylcholine receptor M5 OS=Saimiri boliviensis boliviensis OX=39432 GN=CHRM5 PE=2 SV=1) HSP 1 Score: 256.529 bits (654), Expect = 1.275e-76 Identity = 185/486 (38.07%), Postives = 257/486 (52.88%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSR---ENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIF----------TNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQK-----SENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ I IG+AW+IS +LW P I W + GKR V P EC IQF+ +T TA A++IPV++++ILY RIYRET R K L + G S + + H+ R P L+++ N + S++ S +P+ ATG ST + +E + Y S + A++ L+ + T++ND Y S + P+ + + ++ + C H V + P + +PST LSH +K E KAA+TLSAILLAF ITWTPYNI +++ F + + +++LGYWLCY+NSTVNP+ YALCN TFRKTF +L C K
Sbjct: 54 SFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPPDECQIQFLS-EPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQG-----SVSVTKAEKRKPAHRALFRSCFRCPRPTLVQR-------ERNQASRSSSHRSTSITGKPSQATGPSTNWAKAEELTTCS-SYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEEAEETFVKGQTDKNDCDSPDYFLSPAAAHRPKSQQCVAYKFQLVVKADGTQETNNGC------HKVKIMPCSFPVAKEPSTKGLSPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFC---DKCVPVALWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCQWKK 516
BLAST of Muscarinic acetylcholine receptor vs. UniProt/SwissProt
Match: sp|Q5IS53|ACM5_PANTR (Muscarinic acetylcholine receptor M5 OS=Pan troglodytes OX=9598 GN=CHRM5 PE=2 SV=1) HSP 1 Score: 256.529 bits (654), Expect = 1.275e-76 Identity = 185/486 (38.07%), Postives = 257/486 (52.88%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSR---ENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIF----------TNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQK-----SENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ I IG+AW+IS +LW P I W + GKR V P EC IQF+ +T TA A++IPV++++ILY RIYRET R K L + G S + + H+ R P L+++ N + S++ S +P+ ATG ST + +E + Y S + A++ L+ + T++ND Y S + P+ + + ++ + C H V + P + +PST LSH +K E KAA+TLSAILLAF ITWTPYNI +++ F + + +++LGYWLCY+NSTVNP+ YALCN TFRKTF +L C K
Sbjct: 54 SFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPPDECQIQFLS-EPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQG-----SVSVTKAEKRKPAHRALFRSCFRCPRPTLVQR-------ERNQASRSSSHRSTSITGKPSQATGPSTNWAKAEELTTCS-SYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEEAEETFVKGQTDKNDCDSPDYFLSPAAAHRPKSQQCVAYKFQLVVKADGTQETNNGC------HKVKIMPCSFPVAKEPSTKGLSPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFC---DKCVPVALWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCQWKK 516
BLAST of Muscarinic acetylcholine receptor vs. UniProt/SwissProt
Match: sp|Q9N2A4|ACM3_PANTR (Muscarinic acetylcholine receptor M3 OS=Pan troglodytes OX=9598 GN=CHRM3 PE=3 SV=1) HSP 1 Score: 253.062 bits (645), Expect = 1.055e-74 Identity = 193/516 (37.40%), Postives = 271/516 (52.52%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMH--GLPIKT--------------SYESSNGSRCSNNHKNHSR------ENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDA----ESLNHLVI-------------VNPN-AKEFPNQPSTSNAMVMLSHYSGSQKSE------------NKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
SF V +QL++++NYFLLSLA ADL+IG++SM L+T Y+++ W L CDLWL+IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ +T TA A+++PVTI++ILY+RIY+ET R K L + G +T SYE S +N + + R ++ ++++ SSS + NN +A S + NSA+ S + I E R+IYS + L+ ++ +++ LP S N+ +PEE +D + L++Q+ D +S + L I VN + K P + + ++ +S+ KAA+TLSAILLAF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 92 SFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLE------NSAS--SDEEDIGSE--------TRAIYSIV------LKLPGHSTILNSTKLP-----------------SSDNLQVPEE---ELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFC---DSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLC 561
BLAST of Muscarinic acetylcholine receptor vs. UniProt/SwissProt
Match: sp|P56490|ACM5_MACMU (Muscarinic acetylcholine receptor M5 OS=Macaca mulatta OX=9544 GN=CHRM5 PE=2 SV=1) HSP 1 Score: 251.136 bits (640), Expect = 1.519e-74 Identity = 183/493 (37.12%), Postives = 252/493 (51.12%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGS---------RC-----SNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNS------ATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQK-----SENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ + IG+AW+IS +LW P I W + GKR V EC IQF+ +T TA A++IPV++++ILY RIYRET R K L + G T E + RC + +N + + + ++ N A + P+S AT Q G+ S E E S+ + + K+Q T ++D+ Y S + P+ K + ++ + C H V + P + +PST SH +K E KAA+TLSAILLAF ITWTPYNI +++ F + + T+++LGYWLCY+NSTVNP+ YALCN TFRKTF +L C K
Sbjct: 54 SFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGVMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLS-EPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTEAEKRKPAHRALFRSCLRCPRPTLAQRERNQTSWSSSRRSASTSGKPSQATDPSTNQAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKSRGKESPGE-------EFSSEDAEETFVKAQ-------------TEKHDSDTPNYFLSPAAAHRPKSQKCVAYKFRLVVKADGTQENNNGC------HKVKIMPCSFPVAKEPSTKGLNPNPSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFC---DKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKK 516
BLAST of Muscarinic acetylcholine receptor vs. UniProt/SwissProt
Match: sp|P20309|ACM3_HUMAN (Muscarinic acetylcholine receptor M3 OS=Homo sapiens OX=9606 GN=CHRM3 PE=1 SV=1) HSP 1 Score: 252.677 bits (644), Expect = 1.635e-74 Identity = 193/516 (37.40%), Postives = 271/516 (52.52%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMH--GLPIKT--------------SYESSNGSRCSNNHKNHSR------ENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDA----ESLNHLVI-------------VNPN-AKEFPNQPSTSNAMVMLSHYSGSQKSE------------NKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
SF V +QL++++NYFLLSLA ADL+IG++SM L+T Y+++ W L CDLWL+IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ +T TA A+++PVTI++ILY+RIY+ET R K L + G +T SYE S +N + + R ++ ++++ SSS + NN +A S + NSA+ S + I E R+IYS + L+ ++ +++ LP S N+ +PEE +D + L++Q+ D +S + L I VN + K P + + ++ +S+ KAA+TLSAILLAF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 92 SFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLE------NSAS--SDEEDIGSE--------TRAIYSIV------LKLPGHSTILNSTKLP-----------------SSDNLQVPEE---ELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFC---DSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLC 561
BLAST of Muscarinic acetylcholine receptor vs. TrEMBL
Match: A0A193KU65 (GCR015 OS=Schmidtea mediterranea OX=79327 GN=gcr015 PE=2 SV=1) HSP 1 Score: 947.192 bits (2447), Expect = 0.000e+0 Identity = 531/533 (99.62%), Postives = 532/533 (99.81%), Query Frame = 2
Query: 86 MITEKLSNNDQYYFTSVNLTNRTGSAYAKGLSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQA 1684
MITEKLSNNDQYYFTSVNLTNRTGSAY KGLSLPEIIIYSILGGIVVIITVVGNLLVLTSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVSIWIGIAWIISALLWTPLIYLWPIIDGKRHVKPKECYIQFIQSSYLLTLLTASLAYFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSY+SSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYSKSQSLDSNSSLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQA
Sbjct: 1 MITEKLSNNDQYYFTSVNLTNRTGSAYTKGLSLPEIIIYSILGGIVVIITVVGNLLVLTSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVSIWIGIAWIISALLWTPLIYLWPIIDGKRHVKPKECYIQFIQSSYLLTLLTASLAYFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYQSSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYSKSQSLDSNSSLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQA 533
BLAST of Muscarinic acetylcholine receptor vs. TrEMBL
Match: A0A3Q1H276 (Muscarinic acetylcholine receptor OS=Acanthochromis polyacanthus OX=80966 PE=3 SV=1) HSP 1 Score: 272.322 bits (695), Expect = 1.069e-79 Identity = 193/474 (40.72%), Postives = 259/474 (54.64%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGS--RCSNNH--KNHSRENPFQNLIKK------INSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
SF V RQL++++NYFLLSLAVADL+IG++SM LYT YLV+G W + + CDLWL+IDY SNASV NLL+IS DRY SVTRPLTYR KRT+K+ I IG+AW +S +LW P I LW I G+R V ECYIQF+ ++T TA A+++PVTI+ +LY+RIY+ET R K L + G + S+ GS CS+ + R++ Q L+ + I S R S+ + + + S + N A S+ Q G S + G E+ + +H + +++ + + + + + G N E N SP LS K AK F + T + S E KAA+TLSAILLAF ITWTPYNI +INAF + I T++ +GYWLCY+NSTVNP+ YALCN TFR TF IL C
Sbjct: 110 SFKVNRQLKTVNNYFLLSLAVADLIIGVISMNLYTAYLVMGYWAMGTWACDLWLAIDYVASNASVMNLLVISFDRYFSVTRPLTYRAKRTTKRAGIMIGLAWFVSLVLWAPAILLWKYIKGERTVPSDECYIQFLS-EPIITFCTAMAAFYLPVTIMCVLYWRIYKETQNRSKELAGLQGSGERASFVRQTGSSRSCSSYELTRLSKRKSTCQELVGRFHCWPGIRSWRPGSTR-QGDGDPDQSSSDSWNNNDAA-----ISLDQSGSSEDEDCGG---REMISQSHAIFSIVLSLPGIKAAVNSQLTSCEDLDAASEEDPLRGGANNSE------NTTKSPSVPLSFKEAAM----------------AKRFAARARTQ----ITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLINAF--CKNPCIPGTLWAVGYWLCYVNSTVNPMCYALCNKTFRTTFKMILLC 545
BLAST of Muscarinic acetylcholine receptor vs. TrEMBL
Match: A0A1U7R2Y0 (Muscarinic acetylcholine receptor OS=Alligator sinensis OX=38654 GN=CHRM3 PE=3 SV=1) HSP 1 Score: 266.929 bits (681), Expect = 2.879e-77 Identity = 203/539 (37.66%), Postives = 303/539 (56.22%), Query Frame = 2
Query: 110 NDQYYFTSVNLTN----RTGSAYAKGLSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMH-----GLPIKTSYESSNGSRCSN-----NHKNHSRENPFQ--NLIKKINSLRSSSSNG-KNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQK-------SENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
N+ + FTSV TN TG G ++ ++++ + L GI+ ++T++GN+LV+ +F V +QL++++NYFLLSLA ADL+IG++SM L T Y+++G+W L CDLWLSIDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ ++T TA A+++PVTI+SILY+RIY+ET R K L + ++ +++ + CS+ HS F+ + S + S+ G + + S++S+ ++ ++A L S +E +S+ SI +L + L +K S + + + + ++ + +K ++ +E + + P++ S+ K+ D S V P A + +T L S K E KAA+TLSAIL AF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 46 NESFPFTSVEATNASLNETGKDPLGGHTVWQVVLIAFLTGILALVTIIGNILVIAAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLSTTYIIMGQWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFILWAPAILFWQYFVGKRTVPPNECFIQFLS-VPIITFGTAIAAFYLPVTIMSILYWRIYKETEKRTKELAGLQASGTEAEAVQFVHQTGSSRSCSSYELQQQSLKHSNRRKFRRCHFWLTAKSWKPSADPGDQEHSSSDSWNNN----DAAASLENSASSDEEDIASETRAIYSIVLKLPGHSAILNSTKLPSSEDLHVSGDELQKSDTESKERKHKKLHAQKSVEDEGIFQKSFSKLPVQPGSVAETNKTADGIS---SVATTPAALPLSFKEATLAKKFALKTRSQITKRKRMSLIKEKKAAQTLSAILFAFIITWTPYNIMVLVNTFC---EDCIPKTFWNLGYWLCYINSTVNPMCYALCNKTFRTTFKMLLLC 573
BLAST of Muscarinic acetylcholine receptor vs. TrEMBL
Match: A0A151MH01 (Muscarinic acetylcholine receptor OS=Alligator mississippiensis OX=8496 GN=CHRM5 PE=3 SV=1) HSP 1 Score: 266.544 bits (680), Expect = 4.154e-77 Identity = 203/539 (37.66%), Postives = 302/539 (56.03%), Query Frame = 2
Query: 110 NDQYYFTSVNLTN----RTGSAYAKGLSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMH-----GLPIKTSYESSNGSRCSN-----NHKNHSRENPFQ--NLIKKINSLRSSSSNG-KNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQK-------SENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
N+ + FTSV TN TG G ++ ++++ + L GI+ ++T++GN+LV+ +F V +QL++++NYFLLSLA ADL+IG++SM L T Y+++G+W L CDLWLSIDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW+IS +LW P I W GKR V P EC+IQF+ ++T TA A+++PVTI+SILY+RIY+ET R K L + ++ +++ + CS+ HS F+ + S + S+ G + + S++S+ ++ ++A L S +E +S+ SI +L + L +K S + + + + ++ + +K ++ +E + + P++ S K+ D S V P A + +T L S K E KAA+TLSAIL AF ITWTPYNI ++N F I T +NLGYWLCY+NSTVNP+ YALCN TFR TF +L C
Sbjct: 46 NESFPFTSVEATNASLNETGKDPLGGHTVWQVVLIAFLTGILALVTIIGNILVIAAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLSTTYIIMGQWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFILWAPAILFWQYFVGKRTVPPNECFIQFLS-VPIITFGTAIAAFYLPVTIMSILYWRIYKETEKRTKELAGLQASGTEAEAVQFVHQTGSSRSCSSYELQQQSLKHSNRRKFRRCHFWLTAKSWKPSADPGDQEHSSSDSWNNN----DAAASLENSASSDEEDIASETRAIYSIVLKLPGHSAILNSTKLPSSEDLHVSGDELQKSDTESKERKHKKLHAQKSVDDEGIFQKSFSKLPVQPGSAAETNKTADGIS---SVTTTPAALPLSFKEATLAKKFALKTRSQITKRKRMSLIKEKKAAQTLSAILFAFIITWTPYNIMVLVNTFC---EDCIPKTFWNLGYWLCYINSTVNPMCYALCNKTFRTTFKMLLLC 573
BLAST of Muscarinic acetylcholine receptor vs. TrEMBL
Match: A0A2D0RPZ6 (Muscarinic acetylcholine receptor OS=Ictalurus punctatus OX=7998 GN=LOC108270417 PE=3 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 4.368e-77 Identity = 186/508 (36.61%), Postives = 271/508 (53.35%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLR-SSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQE--------------GESSKFEYG----RSIYS-ELSASNHRLRYXXXXXXXXXXXLPE--PI-----FTNRNDT-------SKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQA 1684
SF V RQL++++NYFLLSLA ADL+IG++SM LYT Y+V+G+W + + CD WL+IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ + IG+AW++S ++W P I W G+R V P +CYIQF+ ++T TA A+++PVTI+S+LY+RIY+ET R + L + G +G R + H R + + + S S S+ + ++ S +R A G+ ++T + Q G S + + G R+I+S LS R + + + E P+ ++ND+ K + +I N+ ++ DS + + + + S + AK F ++ T + S E KAA+TLSAIL AF ITWTPYNI +IN F I +++ LGYWLCY+NSTVNP+ YALCN TFR TF IL C ++ +S Q
Sbjct: 98 SFKVNRQLKTVNNYFLLSLAFADLIIGVISMNLYTTYIVMGQWAMGNWACDFWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAVLMIGLAWLVSFVIWAPAILFWQYFVGERTVPPDKCYIQFLS-EPIITFCTAMAAFYLPVTIMSVLYWRIYKETENRSRELAGLQG----------SGGRLGGAERPHFRISATRASSRSCRSFELSRSAQRQKSLLGLSGHCWKWRSGGAAGIHSRTEVDQRSCDSWNNNDTADHSGSSDEEDSGPSTTRAIFSIVLSLPGMRAAVNSQIKSSEDLGISEEDPLQGTAESVSKNDSLSCSVSNGKKCFASNIANVQSISAIQATATSTDST----NAATNKSASTPISFKEAAL----AKRFVSRARTQ----ITKRKRMSLVKEKKAAQTLSAILFAFIITWTPYNIMVLINTFC---NGCIPESLWALGYWLCYVNSTVNPMCYALCNKTFRNTFKMILLCRWNEKKSKQG 579
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Cavefish
Match: chrm5b (cholinergic receptor, muscarinic 5b [Source:ZFIN;Acc:ZDB-GENE-041001-169]) HSP 1 Score: 253.832 bits (647), Expect = 7.154e-77 Identity = 184/484 (38.02%), Postives = 261/484 (53.93%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPF--RPNSATGLSTQTSIYQEGESSKFEYGRSIY-------SELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDA-ESLNHLVIVNPNAKEFPNQPSTSNA------MVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+V+G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ I IG+AW++S +LW P I W G+R V P +C IQF ++T TA A++IPV++++ILY RIY+ET R K L ++ GL YE N K + + F + S SS+ ++N++ + +S + A L++ TS E + + Y +EL A Y FTN ++ CS N K +P + + +S+RK+ A S L + + ++ P P+ + MV++ E KAA+TLSAILLAF +TWTPYNI +I+ F + I ++++LGYWLCY+NST+NP+ YALCN TF+KTF +L C K
Sbjct: 42 SFKVNSQLKTVNNYYLLSLAFADLIIGVFSMNLYTSYIVMGYWALGNLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGMAWLVSFVLWAPPIICWQYFVGERTVPPDQCQIQFFS-EPVITFGTAIAAFYIPVSVMTILYCRIYKETEKRTKDLAELQGLTSVDKYE---------NSKAQKQRSCFGFNTDGHTTQASWSSSNQSNVTKTTTQSDDMWVKSEQANTLNSYTSSEDEERPASEATSQGSYRNQEPEPNELLACYEESHY----------------FTN------SIKYCSQKNHKKCISYKFKPALTNINPHKTNTESERKTSHACSSSEQLALSSTSSSNKPMDPNLKSQITKRKRMVLI--------KEKKAAQTLSAILLAFILTWTPYNIMVLISTFC---SDCIPLSLWHLGYWLCYVNSTINPMCYALCNKTFQKTFRMLLLCKWKK 482
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Cavefish
Match: chrm3a (cholinergic receptor, muscarinic 3a [Source:ZFIN;Acc:ZDB-GENE-090410-4]) HSP 1 Score: 250.366 bits (638), Expect = 7.432e-75 Identity = 179/508 (35.24%), Postives = 263/508 (51.77%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLR-SSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFT-------NRNDTSKTVYKCSIGNINIPEEVKIRPNR----IDSPIRHLSLKSQRKSCDAESLNHLVIVNPN----------AKEFPNQPSTSNAMVMLSHYSGSQKS------------ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQA 1684
SF V RQL++++NYFLLSLA ADL+IG++SM LYT Y+V+G+W + + CDLWL+IDY SNASV NLL+IS DRY S+TRPLTYR KRT+K+ IG+AW++S +LW P I W G+R C TA A+++PVTI+S+LY+RIY+ET R + L + G +G R + H + + + +S S+ ++++ F+ +RP A + T + +GE S + N+ D+ SLP IF+ R + V C + EE +R +R DS R +S ++R + + + + + + A + P+ P T + ++ ++ E KAA+TLSAIL AF ITWTPYNI ++N F I +++ LGYWLCY+NSTVNP+ YALCN TFR+TF IL C ++ +S Q+
Sbjct: 83 SFKVNRQLKTVNNYFLLSLAFADLIIGVISMNLYTAYIVMGQWAMGNWACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGAMIGLAWLVSLILWAPAILFWQYFVGERTPIITFC--------------TAMAAFYLPVTIMSVLYWRIYKETENRSRELAGLQG----------SGGRLGVPERPHFHLHATRGSSRSCSSFELGRSAQRRSSLLTGRFRCWKWRPGGAGAVGT----HSKGEDQ---------SSCDSWNNN---------DAGLSLPRAIFSIVLNLPGMRAAVTSQVTSCEDLDA-ASEEDPLRGSREDDKSDSLSRSVSNGNKRFATNIAKVQSMPAIEASTTSIDPAAATAMKSPSAPITFKEAALAKRFAARARTQITKRKRMSLIKEKKAAQTLSAILFAFIITWTPYNIMVLVNTFC---NGCIPESLWALGYWLCYVNSTVNPMCYALCNKTFRRTFKMILLCRWNEQKSKQS 540
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Cavefish
Match: ENSAMXT00000026803.2 (pep primary_assembly:Astyanax_mexicanus-2.0:3:12526447:12529953:-1 gene:ENSAMXG00000026077.2 transcript:ENSAMXT00000026803.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 241.891 bits (616), Expect = 3.213e-72 Identity = 176/470 (37.45%), Postives = 248/470 (52.77%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKR----HVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNH--LVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
SF V QLR+ISNY+LLSLAVADL++G VSM LYT Y++ G+W L + CDLWL++DY SNASV NLL+IS DRY SVTRPLTYR KRT K+ ++ I +AW++S LW P I LWP +DGK+ + K+C I F+ + LT TA A+++PV+I+ ILY+RIY E R K L K G S SS G+ + K S +N Q+ + +S+ S + S P R ++ S+ +Y + S L + P ++ + + K + + P +K++ + S + + + ++ +H L P QP T + M+ E KAA+TLSAILLAF +TWTPYNI + + Y V + ++ LGYWLCY+NSTVNP+ YALCN +FR TF +L C
Sbjct: 58 SFRVNSQLRTISNYYLLSLAVADLILGTVSMNLYTAYIIKGQWMLGHLACDLWLALDYVASNASVMNLLVISFDRYFSVTRPLTYRAKRTPKRAAVLITLAWVVSFALWAPAILLWPHVDGKQPGEEDEEVKDCSIPFL-AVPPLTFGTAIAAFYLPVSIMIILYWRIYWEIENRAKGLAKFVG-----SVSSSAGNSIKED-KRPSHQNSAQSSLN--SSMERHSEKHQGVTRKTSVGCFPGRQKQLPLVTADASMLP--PPGGVDYKETCSSSLWNIDDE-------------DDDGPTSSSTEEEHEQDLKGMASSASNPAVIKLKDRQGRSEDQQ-----EIPALAGQAFSHPPLRKARPLDLSLSKQPKTKRRINMIIR-------EKKAARTLSAILLAFILTWTPYNIMVLASLSYCVPEK-----LWQLGYWLCYVNSTVNPMCYALCNESFRATFKTLLLC 486
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Cavefish
Match: chrm5a (muscarinic acetylcholine receptor M5 [Source:NCBI gene;Acc:103025843]) HSP 1 Score: 241.891 bits (616), Expect = 3.628e-72 Identity = 181/503 (35.98%), Postives = 260/503 (51.69%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGS-------RCSNNHKNHSRENPFQNLIKKINSLRSSSSNGK-----------NNISANSFKSHPFRP-------NSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTV-YK----CSIGN---INIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIR 1672
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT ++ I IG+AW++S +LW P I W GKR V ++C IQF ++T TA A++IPV++++ILY RIY+ET R K L ++ G+ T + + R + + ++ +L + S++SS+++ N+ +++ + P P N A G +T + +GE S H ++ P P+ +N + K V YK GN N E+ K + S S K DA +Q + MV++ E KAA+TLSAILLAF +TWTPYNI +I+ F + I ++++LGYWLCY+NSTVNP+ YALCN F+KTF +L C K R
Sbjct: 52 SFKVNSQLKTVNNYYLLSLAFADLIIGVFSMNLYTSYILMGYWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPRRAGIMIGLAWLVSFVLWAPPILCWQYFVGKRTVPERQCQIQFFS-EPVITFGTAIAAFYIPVSVMTILYCRIYKETERRTKDLAELQGVNHSTDSTTDTKAQPQRAIIRSCFSSTSRDKKRSSWSLSSRCKSVKSSAASNDEWSKADQLATFNSYASSDDEDRPISPGVLPAYRNHACG-ENKTGLSNDGE--------------QLSTHE----------DDNFFPSPVKSNSQKSKKCVSYKFKTAAKEGNSLQTNSQEDTKAASFSSAESMSAPSTASSSKPIDA--------------TLKSQITKRKRMVLI--------KERKAAQTLSAILLAFILTWTPYNIMVLISTFC---SDCIPLSLWHLGYWLCYVNSTVNPMCYALCNKNFQKTFRMLLLCQWKKKR 503
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Cavefish
Match: chrm2a (cholinergic receptor muscarinic 2 [Source:NCBI gene;Acc:103039136]) HSP 1 Score: 233.802 bits (595), Expect = 2.800e-69 Identity = 170/491 (34.62%), Postives = 242/491 (49.29%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRH-------------LSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKS-----ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
S V R L++++NYFL SLA ADL+IGL SM LYT Y+V+G WPL +CDLWL++DY +SNASV NLLIIS DRY VT+PL+Y +KRT+K + I AW++S +LW P I W I G R V +ECYIQF + +T TA A+++PV I+ +LY++I R + R +K +G+ + +R S+ +S + N + + P R G + T SK + G++ + R R + P+ + T + N E V R N + RH + KS + C A S + IV K Q + + +V ++ +K E K +T+ AIL+AF TWTPYN+ +IN F + I TV+ +GYWLCY+NST+NP YALCN TF+KTF +L C IRS +
Sbjct: 57 SIKVNRSLQTVNNYFLFSLACADLIIGLCSMNLYTVYIVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLSYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEQECYIQFFS-NAAVTFGTAIAAFYLPVIIMMVLYWQISRASKSR-----------VKKDNRKPSGANVGPASPSQTR------------SIMASKPDNNNMVVED-----PDR-----GQTQTTDDVTNQHDSKLQNGKAPSTAAGEEEDRTRNNCI-----------PVEEKESSNDSTSGSGAAANQKEEETVPSRANDGQATARHHTKAGGSKLTCIKIVTKSPKGDCYAPSNTTVEIVPATEK----QNNVTRKIVKMTKQPPKKKKAAPSREKKVTRTIMAILVAFVATWTPYNVMVLINTFC---SSCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLLCQYKNIRSAR 495
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Sea Lamprey
Match: CHRM3 (cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952]) HSP 1 Score: 244.973 bits (624), Expect = 8.782e-74 Identity = 171/483 (35.40%), Postives = 251/483 (51.97%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG---------LPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSI-------GNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVN-PNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSI 1660
SF V +QL +++NY+LLSLAVADL+IG+ SM L+T Y+++G W L CDLWL++DY SNASV NLL+IS DR+ S+TRPLTYR KRT + ++ IG+AW++S +LW P I W I G+R V P EC IQF+ ++T TA A+++PVTI++ +Y+RI++E R + L + G + E + + + P + ++ SS NG + S++ + P + + + G S + + L+A N R P P R ++ Y CS + ++ + R H S R+ C A S + + + AK F + N + + S E KAA+TLSAILLAF ITWTPYNI +++ F P+ ++N+GYWLCY+NSTVNP+ YALCN FRKTF +L C +
Sbjct: 84 SFKVNKQLHTVNNYYLLSLAVADLIIGIFSMNLFTCYMIMGHWALGSLACDLWLALDYVASNASVMNLLVISFDRFFSITRPLTYRAKRTPHRAALLIGLAWVVSFVLWAPAILFWQYIVGERTVPPDECRIQFLS-EPIITFCTAIAAFYLPVTIMATIYWRIFKEIQNRARDLAMLQGSVSEGREELEQEEDMVELGDEKEEEEEESTQAVDTPQASGERRRVGNNSSKDNGATSASSH-YSEKDDAPKKHRAIYSMVMVLPSGRCSAM-HASKVTGRLTAQNVDTRD------------PMPSHETRIRAVRS-YNCSDRSGQTDGASPSLRQTASERSPAESDASDHSSTSDTREVCAASSSTRISMRDLSTAKRFTSAALKVN---VTARKRMSLIKEKKAARTLSAILLAFIITWTPYNIMVLMSTFCPECVPPV---LWNIGYWLCYVNSTVNPVCYALCNRIFRKTFRQLLLCQL 544
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Sea Lamprey
Match: CHRM3 (cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952]) HSP 1 Score: 179.104 bits (453), Expect = 1.459e-49 Identity = 100/191 (52.36%), Postives = 137/191 (71.73%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSN 835
+F V RQL++++NYFLLSLAVADL+IG+VSM LYT Y+++ W L CDLWL +DY SNASV NLL+IS DRY S+TRPL Y+ KRT+K+V++ IG+AW++S +LW P I W +DGKR V EC+IQF+ +T TA A+++PVTI+ +LY+RIY ET R + L + G + +ESS+
Sbjct: 36 AFKVNRQLKTVNNYFLLSLAVADLIIGVVSMNLYTTYIIMSRWALGQAACDLWLVVDYVASNASVMNLLVISFDRYLSITRPLKYKAKRTTKRVALMIGLAWVVSLVLWGPAILFWQYVDGKRTVPDNECFIQFLS-VPAITFGTAIAAFYLPVTIMMVLYWRIYLETQKRTRELAGLQG----SQFESSS 221 HSP 2 Score: 65.0846 bits (157), Expect = 2.071e-11 Identity = 27/43 (62.79%), Postives = 33/43 (76.74%), Query Frame = 2
Query: 1547 YNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRS 1675
+ LGYWLCY+NSTVNP+ YALCN TFRKTF IL C + ++
Sbjct: 454 WRLGYWLCYVNSTVNPMCYALCNKTFRKTFKWILLCQWERWKT 496
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Sea Lamprey
Match: chrm5b (cholinergic receptor, muscarinic 5b [Source:ZFIN;Acc:ZDB-GENE-041001-169]) HSP 1 Score: 175.637 bits (444), Expect = 2.434e-48 Identity = 98/194 (50.52%), Postives = 132/194 (68.04%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSR 844
SF V RQL+++SNYFLLSLA ADL++GL SM LYT Y++ G W + +CDLWL++DY SNASV NLL IS DRY S+TRPL Y+ KRT ++ SI IG+AW +S +LW P I W + GKR V +CYIQF+ ++T TA A+++P+TI+ +LY+RIYRET R + + G K+ G+R
Sbjct: 54 SFRVSRQLKTVSNYFLLSLAAADLIVGLFSMNLYTAYILTGRWAMGAVMCDLWLTLDYVASNASVMNLLAISFDRYFSITRPLKYKAKRTKRRASIMIGLAWAVSLVLWAPAILFWQHMVGKRTVPQDQCYIQFLS-EPIITFGTAIAAFYLPITIMMVLYWRIYRETRRRSRQFATLQGSESKSRSHVPTGTR 246 HSP 2 Score: 99.7525 bits (247), Expect = 2.127e-22 Identity = 44/79 (55.70%), Postives = 58/79 (73.42%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
+NKA + L AILLAF +TWTPYNI +++ F + +++LGYWLCY+NSTVNP+ YALCN+ FRKTF IL+C
Sbjct: 443 DNKAVRILCAILLAFIVTWTPYNIMVLVSTFCD---DCVPKKLWHLGYWLCYVNSTVNPMCYALCNMHFRKTFKTILSC 518
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Sea Lamprey
Match: chrm4a (cholinergic receptor, muscarinic 4a [Source:ZFIN;Acc:ZDB-GENE-090410-6]) HSP 1 Score: 125.176 bits (313), Expect = 6.371e-31 Identity = 84/171 (49.12%), Postives = 112/171 (65.50%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLR 775
S V R+L+++++YF+ SLA ADL+IG SM +Y Y+ G WPL +CDLWLSIDY SNASV NLLIIS DR+ V+RP TY +RT++ +I I AW++S LLW P I LW ++G R V CYIQF + TL TA A+++PV ++ ILY I R + R
Sbjct: 58 SICVNRRLQTVNSYFIFSLACADLIIGAFSMNVYAVYVWRGAWPLGAALCDLWLSIDYVASNASVMNLLIISCDRFLCVSRPHTYPARRTARAAAIVIAAAWLLSLLLWAPAIVLWQFVEGVRTVPQDACYIQFFS-NPAATLGTAIAAFYLPVAVMCILYLYILRASRCR 227 HSP 2 Score: 86.6557 bits (213), Expect = 2.746e-18 Identity = 37/87 (42.53%), Postives = 57/87 (65.52%), Query Frame = 2
Query: 1397 YSGSQ-KSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
+ G++ + E K +T++A+LLAF +TWTPYN+ ++ F T + + LGYWLCY+NS VNP YALC F++TF+ ++ C
Sbjct: 378 FGGARARRERKLTRTVAAVLLAFIVTWTPYNVMVLLAVFCT---DCVPHAAWELGYWLCYVNSAVNPACYALCIREFKRTFLQLMRC 461
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006872.1 (pep scaffold:Pmarinus_7.0:GL476537:253210:263579:1 gene:ENSPMAG00000006208.1 transcript:ENSPMAT00000006872.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.5817 bits (218), Expect = 1.684e-19 Identity = 54/171 (31.58%), Postives = 93/171 (54.39%), Query Frame = 2
Query: 269 IVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKK--VXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLR 775
++E++LR+++ F++SLA ADL++ + MP Y V G W C +W+S D AS+ L IS+DRYCSV+ P Y + + KK V++ I S + + P++ W I G +EC ++ ++ ++LA++IP ++ +YF IYR + L+
Sbjct: 44 VLEKRLRTVTYMFIMSLATADLLVACLVMPFSIIYEVTGRWMFGRIFCKVWISFDVMFCTASIVTLCFISLDRYCSVSAPHRYTLPKEPKKICVAMTAAIWVYSSLISFLPVMRGWNEIPGLDFDSSRECV---FVTNRTFAVVASALAFYIPFLVMCTMYFFIYRASRLK 211 HSP 2 Score: 56.6102 bits (135), Expect = 6.398e-9 Identity = 29/81 (35.80%), Postives = 43/81 (53.09%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYT--VETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
E+KA +T+S I+ AF + W PY F V FY+ ++ + + + WL Y NS +NP+LYA N F+ I C
Sbjct: 237 EHKATRTMSIIISAFVLCWLPYFFFNVFIGFYSNNEDSAHVVQMAFKVITWLGYCNSAINPMLYAFLNRDFQHALRKIFIC 317
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Nematostella
Match: EDO35211 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM55]) HSP 1 Score: 84.7297 bits (208), Expect = 4.617e-18 Identity = 44/95 (46.32%), Postives = 64/95 (67.37%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPY--YICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKK 541
+F + R LR+++NYF++SLA+ADL++G VSMPL+ YLV +WP P I LWL D + AS+ NL +IS+DR+ ++T P Y K T K+
Sbjct: 25 AFYLFRDLRTVTNYFVVSLAIADLLVGFVSMPLWFTYLVF-QWP-PQNSEIYALWLCFDIATATASIMNLAVISVDRFYAITLPFQYSQKITKKR 117
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Nematostella
Match: EDO33023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STC6]) HSP 1 Score: 76.2554 bits (186), Expect = 6.611e-15 Identity = 42/92 (45.65%), Postives = 61/92 (66.30%), Query Frame = 2
Query: 272 VERQLRSI-SNYFLLSLAVADLMIGLVSMPLYTGYLVVGE-WPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKK 541
V +LRS +NYF+ SLAV+DL++ LVS+PL ++ W L C LW+ D S +SV NL IIS+DRY +++RPL YR++ TS++
Sbjct: 46 VNNRLRSSPANYFIASLAVSDLLVALVSLPLRIDQMLHNHNWCLSLEACALWIWSDMICSGSSVGNLAIISMDRYIALSRPLHYRMQVTSQR 137
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Nematostella
Match: EDO35278 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM06]) HSP 1 Score: 73.1738 bits (178), Expect = 2.395e-14 Identity = 37/94 (39.36%), Postives = 58/94 (61.70%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVG-EWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKK 541
+F R+LR+ +NYF++SLA+AD+++ L SMP++ YL+ G W + +W +D AS+ NL ISI+R +T PLTY TS++
Sbjct: 20 AFKTYRKLRTKTNYFVVSLAIADILVSLFSMPIWAAYLLTGPNWIFSETLQRIWTGVDILCGVASIINLAAISIERCICITHPLTYHTTMTSRR 113
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Nematostella
Match: EDO35293 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM07]) HSP 1 Score: 72.7886 bits (177), Expect = 2.451e-14 Identity = 37/94 (39.36%), Postives = 58/94 (61.70%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVG-EWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKK 541
+F R+LR+++N+F++SLA AD++I SMP++ YL+ G +W + +W +D AS+ NL ISI+RY +T PL+Y T KK
Sbjct: 18 AFRAVRKLRTVTNFFVVSLAAADILIASFSMPIWGAYLLTGPDWVFSLNLMKMWTCMDIMCGVASIINLSAISIERYLCITFPLSYHTTMTPKK 111 HSP 2 Score: 56.9954 bits (136), Expect = 5.575e-9 Identity = 31/79 (39.24%), Postives = 46/79 (58.23%), Query Frame = 2
Query: 1412 KSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAIL 1648
SE +AAKTL+ ++ AF ++W P F ++N Y + IG + W+ Y NS NP++YA N FR TF++IL
Sbjct: 189 ASEIRAAKTLAVVMGAFVVSWGP---FFILNLVYGFCPECIGLEAIVVTKWMHYCNSVCNPIVYACMNKDFRATFVSIL 264
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Nematostella
Match: EDO35450 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLG6]) HSP 1 Score: 71.2478 bits (173), Expect = 1.408e-13 Identity = 34/89 (38.20%), Postives = 60/89 (67.42%), Query Frame = 2
Query: 278 RQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGE-WPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKK 541
R+LR+++NYF++SLAV+DL++ +SMP + + W L +C+ W+ +D S+AS+ NL +IS+DR+ +++ PLTY T ++
Sbjct: 38 RRLRTVTNYFIISLAVSDLLVAGLSMPFRIHHTLHSMCWDLGISVCEFWIFVDLVCSSASICNLSMISVDRFLALSYPLTYPSIMTKRR 126
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Medaka
Match: chrm5a (muscarinic acetylcholine receptor M5 [Source:NCBI gene;Acc:101169892]) HSP 1 Score: 244.588 bits (623), Expect = 3.341e-73 Identity = 185/495 (37.37%), Postives = 260/495 (52.53%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGL----------PIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGK------NNISANSFKSHPFRPNSATGLSTQTSIY-QEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLS--LKSQRKSCDAESLNHLVIVNPNAKEFP------NQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIR 1672
SF V QL++++NY+LLSLA ADL+IG+ SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT ++ +I IG+AW++S +LW P I W GKR V ++C IQF ++T TA A++IPV++++ILY RIY+ET R K L ++ G+ P KT S C +H + + + +S++SN + NS+ S + QTS+ E E SK G S+ +LS T R TS+ KC K +P + + H S S+ S S + + + ++ P NQ + +V++ E KAA+TLSAILLAF +TWTPYNI +I+ F + I ++++LGYWLCY+NSTVNP+ YALCN TF+KTF +L C K R
Sbjct: 52 SFKVNSQLKTVNNYYLLSLAAADLIIGVFSMNLYTSYILMGYWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPRRAAIMIGLAWLVSLILWAPPILCWQYFVGKRTVPERQCQIQFFS-EPVITFGTAIAAFYIPVSVMTILYCRIYKETEKRTKDLAELQGVNYLADSGVTKPQKTIIRSCFS--CKLRSTSHEMNQASWSSCSRSTAAKSAASNSDEWSKVGQLTTFNSYASSEEDDRPVSPADFQTSLRNAECEDSKSGVG-SVSEQLSFFQ----------------------TPRRSTSQKSSKCV--------SYKFKPMAQEPHMEHHSNNRDSKMVSSVFSSAESMTVPSTSSASKPIDGTLKNQITKRKRLVLI--------KERKAAQTLSAILLAFILTWTPYNIMVLISTFC---SDCIPLSLWHLGYWLCYVNSTVNPMCYALCNKTFQKTFRMLLLCQWKKKR 501
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Medaka
Match: chrm2a (cholinergic receptor muscarinic 2 [Source:NCBI gene;Acc:101157989]) HSP 1 Score: 228.409 bits (581), Expect = 1.076e-67 Identity = 171/479 (35.70%), Postives = 247/479 (51.57%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSEN------KAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQ 1681
S V R L++++NYFL SLA ADL+IGL SM LYT Y+V+G WPL +CDLWL++DY +SNASV NLLIIS DRY VT+PL+Y +KRT+K + I AW++S +LW P I W I G R V KECYIQF + +T TA A+++PV I+ LY++I R + R +KK + P +N S + S P N + ++ S + +N +S +T + E ESS S+ ASN + EP + N ++T + IP + R S + + +K++ D + ++ + A E N + +V ++ ++K + K +T+ AIL+AF TWTPYN+ +IN F + I TV+ +GYWLCY+NST+NP YALCNVTF+KTF +L C IRS +
Sbjct: 42 SIKVNRNLQTVNNYFLFSLACADLIIGLCSMNLYTVYIVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLSYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEKECYIQFFS-NAAVTFGTAIAAFYLPVIIMIQLYWQISRASKSR---VKKDNRKP-----SGANPEPLSPVQRRSSTPKPNNNNVPGEDAGHSQNQKLQNGKGPSS--------------TTNCTPGDEKESSNDSTSVSVV----ASNQKDE--------------EPAPSTANSCAETSQQ-------IPRQ---RAKAGGSKLTCIKIKTKSPKGDYYTPSNATVEIVPATERQNH--VARKIVKMTKQPPNKKKKGAPSREKKVTRTIMAILVAFVATWTPYNVMVLINTFC---SSCIPNTVWTIGYWLCYINSTINPACYALCNVTFKKTFKHLLMCQYKNIRSAR 464
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Medaka
Match: chrm3a (muscarinic acetylcholine receptor M3 [Source:NCBI gene;Acc:101164585]) HSP 1 Score: 189.504 bits (480), Expect = 9.592e-52 Identity = 102/180 (56.67%), Postives = 133/180 (73.89%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHG 802
SF V RQL++++NYFLLSLAVADL+IG++SM LYT YL++G W + + CD+WL+IDY SNASV NLL+IS DRY S+TRPLTYR KRT+++ I IG+AW +S +LW P I LW G+R V P ECYIQF + T TA A+++PVTI+S+LY+RIY+ET R K L + G
Sbjct: 101 SFKVNRQLKTVNNYFLLSLAVADLIIGIISMNLYTSYLIMGYWAMGNWACDIWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTRRAGIMIGLAWFVSFVLWAPAILLWQYFVGERTVPPNECYIQFFS-EPITTFCTAMAAFYLPVTIMSVLYWRIYKETQNRSKELAGLQG 279 HSP 2 Score: 108.227 bits (269), Expect = 3.326e-24 Identity = 53/79 (67.09%), Postives = 60/79 (75.95%), Query Frame = 2
Query: 1418 ENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
E KAA+TLSAILLAF ITWTPYNI +INAF V I T++ +GYWLCY+NSTVNP+ YALCN TFR TF IL C
Sbjct: 535 EKKAAQTLSAILLAFIITWTPYNIMVLINAFCEV---CIPDTLWAVGYWLCYVNSTVNPMCYALCNKTFRTTFKMILLC 610
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Medaka
Match: ENSORLT00000022971.2 (muscarinic acetylcholine receptor M1-like [Source:NCBI gene;Acc:101171981]) HSP 1 Score: 177.178 bits (448), Expect = 1.049e-48 Identity = 112/274 (40.88%), Postives = 164/274 (59.85%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNG--KNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFE-YGRSIYSE 1075
SF + + L++++NY+LLSLA ADL+IG +SM LYT Y+++G W L +CDLWL+IDY SNASV NLLIIS DRY SVTRPLTYR KRT+K+ IG+AW IS +LW P I W + G+R V P+ECYIQF+ + + T TA A+++PVT+++ L+++IY+ET R K ++ + G C++ NL + ++ + G K+N S K H R +S+ L Q ++ S F+ + +S+ E
Sbjct: 38 SFKINKTLKTVNNYYLLSLAFADLIIGTLSMNLYTTYIIMGHWALGPVLCDLWLAIDYVASNASVMNLLIISFDRYFSVTRPLTYRAKRTTKRTMAMIGLAWSISFVLWAPAILFWQYVVGERTVPPEECYIQFL-TEPVTTFCTAIAAFYLPVTVMAFLFWKIYQETEKRAKDIQSLKG-------------SCAST-----------NLNQTVSEMSEGVGEGSIKSNQRNTSVKLHLVRTSSSRKLCHQDGPARDPRGSDFDKFEKSVEEE 286 HSP 2 Score: 94.3597 bits (233), Expect = 3.507e-20 Identity = 46/74 (62.16%), Postives = 53/74 (71.62%), Query Frame = 2
Query: 1433 KTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
+TLSAILLAF +TW PYNI +IN F I ++ LGYWLCY+NSTVNP+ YALCN TFR TF AIL C
Sbjct: 353 RTLSAILLAFMMTWLPYNIMVLINTFCQ---NCIPEALWALGYWLCYVNSTVNPMCYALCNKTFRTTFRAILMC 423
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Medaka
Match: chrm5b (cholinergic receptor, muscarinic 5b [Source:ZFIN;Acc:ZDB-GENE-041001-169]) HSP 1 Score: 176.792 bits (447), Expect = 2.021e-48 Identity = 112/243 (46.09%), Postives = 154/243 (63.37%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRS--SSSNGKNNISAN----SFKSH 973
SF V QL++++NY+LLSLA ADL+IG++SM LYT Y+++G W L CDLWL++DY SNASV NLL+IS DRY S+TRPLTYR KRT K+ +I IG+AW+IS +LW P I W G+R V +C IQF+ + + YF PV++++ILY RIY+ET R K L ++ G + S+ SSN SN + SR + + +I SL S SS +++IS + SFK
Sbjct: 46 SFKVNSQLKTVNNYYLLSLAFADLIIGVLSMNLYTTYILMGYWSLGNLACDLWLAVDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAAIMIGLAWLISFVLWAPPILCWQYFVGERKVPTDQCQIQFLTEPVITFGTAIAAFYF-PVSVMTILYCRIYKETQKRTKDLAELQGNQNQASWSSSNQ---SNATRTTSRSDDSWAKVDQITSLNSYTSSEEEEHHISKDTPQGSFKEQ 284 HSP 2 Score: 103.605 bits (257), Expect = 3.719e-23 Identity = 53/107 (49.53%), Postives = 69/107 (64.49%), Query Frame = 2
Query: 1334 PNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTC 1654
P NQ + MV++ E KAA+TLSAILLAF +TWTPYNI +I+ F I T++++LGYWLCY+NST+NP+ YALCN TF+KTF +L C
Sbjct: 352 PMDTALKNQITKRKRMVLVK--------EKKAAQTLSAILLAFILTWTPYNIMVLISTFCA---DCIPTSLWHLGYWLCYVNSTINPMCYALCNKTFQKTFRMLLLC 447
BLAST of Muscarinic acetylcholine receptor vs. Planmine SMEST
Match: SMESG000018810.1 (SMESG000018810.1) HSP 1 Score: 825.854 bits (2132), Expect = 0.000e+0 Identity = 445/450 (98.89%), Postives = 449/450 (99.78%), Query Frame = 2
Query: 335 MIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQA 1684
MIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVSIWIGIAWIISALLWTPLIYLWPIIDGKRHVKPKECYIQFIQSSYLLTLLTASLAYFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSY+SSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYSKSQSLDSNSSLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIR+ ++
Sbjct: 1 MIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVSIWIGIAWIISALLWTPLIYLWPIIDGKRHVKPKECYIQFIQSSYLLTLLTASLAYFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYQSSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYSKSQSLDSNSSLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRTYES 450
BLAST of Muscarinic acetylcholine receptor vs. Planmine SMEST
Match: SMESG000018810.1 (SMESG000018810.1) HSP 1 Score: 813.527 bits (2100), Expect = 0.000e+0 Identity = 439/444 (98.87%), Postives = 443/444 (99.77%), Query Frame = 2
Query: 353 MPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRSTQA 1684
MPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVSIWIGIAWIISALLWTPLIYLWPIIDGKRHVKPKECYIQFIQSSYLLTLLTASLAYFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSY+SSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYSKSQSLDSNSSLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIR+ ++
Sbjct: 1 MPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVSIWIGIAWIISALLWTPLIYLWPIIDGKRHVKPKECYIQFIQSSYLLTLLTASLAYFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYQSSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYSKSQSLDSNSSLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISKIRTYES 444
BLAST of Muscarinic acetylcholine receptor vs. Planmine SMEST
Match: SMESG000033753.1 (SMESG000033753.1) HSP 1 Score: 225.713 bits (574), Expect = 9.554e-67 Identity = 186/475 (39.16%), Postives = 264/475 (55.58%), Query Frame = 2
Query: 140 LTNRTGSAYAKGLSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKMHGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSSSNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDTSKTVYKCSIGNINIPEEVKIRPNRIDSPIRHLSLKSQRKSCDAESLN-HLVIVNPNAKEFPNQPSTSNAMVM--LSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQPIGTTVYNL 1555
L N T + + L++ EIIIYS L IV+ IT+ GN+LV+ F ++ LR +SNYFL+SLAV+DL IG++SMPLYT +L++ +WP IC++WL++DYT+SNASVANL IIS+DRY SV P++YRIKRT+KKV WI AW++SAL+W PLI + P++ + ECY+QF+ +LT+L +SL YFIP II++LY +IYR T R + +N SR SN E+ IK + S+ N + +HP + L+ S++Q +F R +S+ SNH LR + T N K K S+ IP+E ++ I+S SQ + D ++ H I P+ N+ + + +V+ H K + KAAK LSAILL F ITWTPYN+FT+INAFY +PIG T+YN+
Sbjct: 2 LNNSTIISSPQKLNVTEIIIYSFLSFIVIFITIAGNILVIVGFCYKKSLRFLSNYFLISLAVSDLFIGVISMPLYTTFLILDKWPFSNTICNIWLTVDYTVSNASVANLFIISLDRYLSVKSPISYRIKRTNKKVIKWIICAWVVSALIWVPLINVIPVMFKSHSIPFGECYVQFLFFLPILTVLVSSLVYFIPTIIIAVLYIQIYRTTQTRTLI--------------KTNFSRSSNIQLCEKSEH-----IKFWQRVTCPSTEDLNKM------NHPREYFRSISLA---SLFQRPSIIRFTNHR--FSK--DSNHFLRTNTKLMK-----------TISNSVEKISDKESVSITFIPDEKNLKSQMINS-------VSQSFASDINEIDCHRKIHKPSI--ISNRSDSYSVIVVNNCVHRKRIHKPDKKAAKILSAILLVFIITWTPYNVFTIINAFYPPMKKPIGKTLYNI 424
BLAST of Muscarinic acetylcholine receptor vs. Planmine SMEST
Match: SMESG000081829.1 (SMESG000081829.1) HSP 1 Score: 187.578 bits (475), Expect = 4.087e-53 Identity = 129/270 (47.78%), Postives = 179/270 (66.30%), Query Frame = 2
Query: 140 LTNRTGSAYAKGLSLPEIIIYSXXXXXXXXXXXXXXXXXXXSFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYRETNLRQKVLKKM-------HGLPIKTSYESSNGSRCSNNHKNHSRENPFQNLIKKINSLRSSS 928
+ N T L +I+IYS++ I+ + T GNLLVL SF +E QLR+ISNY+LLSLAV+D +IG++SMPLY+ +L++ WP CDLWLS+DYT+SNAS ANL++IS DRY ++T PLTYR KR+ +K I I + WII ALLWTPLIY+WPIIDGKR V +CY+QF++SS LLTLLT ++ Y IP+ II + +IYR T R K L+ + G +K ++ + + S+ S NP + IKK++ + +S
Sbjct: 1 MNNETNPDPFMALPFYQILIYSLIATILSLATACGNLLVLISFCIEGQLRTISNYYLLSLAVSDFLIGIISMPLYSTFLIMQFWPFNSTTCDLWLSLDYTVSNASSANLVLISYDRYKTLTCPLTYRCKRSPRKTIIIILLTWIICALLWTPLIYIWPIIDGKRTVPQGKCYVQFMESSTLLTLLTCAIGYLIPLFIIIVFAIQIYRVTRHRNKNLQTLGYATPVYGGAALKYNHRDNYKNMDSSTDTEISNRNPKEKCIKKVHKFQPNS 270 HSP 2 Score: 109.768 bits (273), Expect = 1.754e-25 Identity = 51/87 (58.62%), Postives = 68/87 (78.16%), Query Frame = 2
Query: 1409 QKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQP-IGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
+ S +KAAKTL+AI++AFF+TW PYN+FT+IN + ++ P IGT +Y GY+LCYLNST+NP+LYA CN+ FR+TF IL C SK
Sbjct: 309 KPSSSKAAKTLAAIIIAFFVTWFPYNLFTLINLYSRSKSNPTIGTLLYGFGYYLCYLNSTINPILYAYCNIMFRRTFWRILICGRSK 395
BLAST of Muscarinic acetylcholine receptor vs. Planmine SMEST
Match: SMESG000027386.1 (SMESG000027386.1) HSP 1 Score: 171.014 bits (432), Expect = 3.524e-46 Identity = 151/499 (30.26%), Postives = 245/499 (49.10%), Query Frame = 2
Query: 263 SFIVERQLRSISNYFLLSLAVADLMIGLVSMPLYTGYLVVGEWPLPYYICDLWLSIDYTMSNASVANLLIISIDRYCSVTRPLTYRIKRTSKKVXXXXXXXXXXXXXXWTPLIYLWPIIDGKRHVKPKECYIQFIQXXXXXXXXXXXXXXFIPVTIISILYFRIYR-------ETNLRQKVLKKMHGLPIKTSYESSNGSRCSN-----NHKNHSRENPFQNLIKKINSLRSSS---SNGKNNISANSFKSHPFRPNSATGLSTQTSIYQEGESSKFEYGRSIYSELSASNHRLRYXXXXXXXXXXXLPEPIFTNRNDT---SKTVYKCSIGNI-----NIPEEVKIRPNRIDSPI-----RHLSLKSQRKSCDAESLNHLVIVNPNAKEFPNQPSTSNAMVMLSHYSGSQKSENKAAKTLSAILLAFFITWTPYNIFTVINAFYTVETQP---IGTTVYNLGYWLCYLNSTVNPLLYALCNVTFRKTFIAILTCSISK 1666
+FI+E+++R SNYF+ SLA+ D++IGL SM L++ Y+V+G WPL Y +C++WLS DYT+ S +L+I++DRYCSV P YRI RT KKV + I +AWII A L+ +I +W V ++C+ +F + + ++I + I+ +LY IYR ++ ++K L + +T + G +N KN ++NPF + N L + + +NN S +S S P+ T +I+ + S +++++ LR+S + D +L E I D+ SKT Y+ +I N N+P + I + + R + KS + +L A F + + + ++S ++KS KT+S IL AF I WTPY++ +I F + P I +YN YWLCY+NS +NP YAL N F+KT + ++ S+
Sbjct: 44 AFIMEKKIRIPSNYFIASLAITDILIGLFSMNLFSIYVVLGYWPLGYILCNIWLSFDYTVCLTSQYTVLLITVDRYCSVKIPAKYRIWRTEKKVYLLIVLAWIIPACLFITIIIIWNCRSQSPSVDSQQCFAEF-TLYPIFNTVFTIAYFWITLIIMCVLYIGIYRVARRLHQNSDTKRKRLTSLMATAGQTMSKIGVGLSLANLDVNVQFKNFLKDNPFNETTTERNLLNDNCLYPDSSRNNYSISSRVS----PSEETNSLMINNIFPKSHS------ETLFTD------SLRFSPKSNKDKCLNLFEDIQYIDEDSSGDSKTNYEFNISNFYTNRYNLP-SINISQSEVHGKFHLENNREIKYKSWDNTVSKSAL--------KAMRFLKSVHNMSKRIDIRNHSKAKKS----LKTISFILGAFIICWTPYHVLILIKGF--CDNPPKSCINDVLYNASYWLCYINSPINPFCYALSNSQFKKTLLKLIKGDFSR 510 The following BLAST results are available for this feature:
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Muscarinic acetylcholine receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015707 ID=SMED30015707|Name=Muscarinic acetylcholine receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1843bpback to top protein sequence of SMED30015707-orf-1 >SMED30015707-orf-1 ID=SMED30015707-orf-1|Name=SMED30015707-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=536bp MITEKLSNNDQYYFTSVNLTNRTGSAYAKGLSLPEIIIYSILGGIVVIITback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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