IQ domain-containing protein D

Overview


Name	IQ domain-containing protein D
Smed ID	SMED30015703
Length (bp)	1658

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of IQ domain-containing protein D (SMED30015703) t-SNE clustered cells

Violin plots show distribution of expression levels for IQ domain-containing protein D (SMED30015703) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of IQ domain-containing protein D (SMED30015703) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for IQ domain-containing protein D (SMED30015703) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015703

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30015703	h1SMcG0005415	SmedASXL_011353	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015703	h1SMcG0005415	Contig39634	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015703	h1SMcG0005415	Contig39634	newmark_ests	PMID:29674431 Fincher et al., 2018
head region	SMED30015703	h1SMcG0005415	dd_Smed_v6_7079_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
ciliated epithelial cell	SMED30015703	h1SMcG0005415	dd_Smed_v4_7079_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of IQ domain-containing protein D vs. Ensembl Human
Match: IQCD (IQ motif containing D [Source:HGNC Symbol;Acc:HGNC:25168])

HSP 1 Score: 143.665 bits (361), Expect = 7.079e-37
Identity = 127/429 (29.60%), Postives = 216/429 (50.35%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTAL---TTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            D  K L  +R KLTT+E +RIMS+LD  I + E++T +  V +N EDM  +L        D  + ++   D+    L+ +R +++  +Q      +EQ  A E+ W   +    E             S SP                   L +++K +T+ +     +NP A   L   T G       RS     FI  L++L+  L  +L+T+P E  +   +L+ ++ +   NQ II+ LE EL    +++  ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q++ D + S++   K+QQEI Q ++++ N++ E R  E+ +R  K K E+ +E  +Q YDT M + Q E E +D  + EEK  L E+  R K +  E+ +I EE+ I  +KR  A +E   + +A   IQA W+ Y
Sbjct:   32 DPLKPLVLSRTKLTTIEAKRIMSILDEAIYKVELVTLLSYVASNREDMEGMLGE------DVMRAVREHEDLCQVLLENVRCLKEKERQ-----LQEQKEAEEEGWLRDRLLSIE---------LQKSSLSP-------------------LMQQIKDSTKNVLRLLLSNPQAARLLQMQTQG-------RSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDISRQNSNNQQIIDTLEKELAERMKNRNAEVEKENFVIQELKNHLHQVLKFSENSLVRTKQEAEKQQKADFRASQARVAKIQQEILQLQSQFYNLVMENREAEQALRKKKYKVETEIENWIQKYDTEMGEKQEELEDLDAVHREEKISLEELRRRHKVLVGEFAQIREEREINSKKRMEAEQEMVRMVRAATLIQALWKGY 414

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BLAST of IQ domain-containing protein D vs. Ensembl Human
Match: IQCD (IQ motif containing D [Source:HGNC Symbol;Acc:HGNC:25168])

HSP 1 Score: 107.071 bits (266), Expect = 2.248e-24
Identity = 94/344 (27.33%), Postives = 171/344 (49.71%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTAL---TTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESA 1236
            D  K L  +R KLTT+E +RIMS+LD  I + E++T +  V +N EDM  +L        D  + ++   D+    L+ +R +++  +Q      +EQ  A E+ W             R+    I    S                +   L +++K +T+ +     +NP A   L   T G       RS     FI  L++L+  L  +L+T+P E  +   +L+ ++ +   NQ II+ LE EL    +++  ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q++ D + S++   K+QQEI Q ++++ N++ E R  E+ +R  K+ +E+A
Sbjct:   32 DPLKPLVLSRTKLTTIEAKRIMSILDEAIYKVELVTLLSYVASNREDMEGMLGE------DVMRAVREHEDLCQVLLENVRCLKEKERQ-----LQEQKEAEEEGWL------------RDRLLSIELQKS----------------SLSPLMQQIKDSTKNVLRLLLSNPQAARLLQMQTQG-------RSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDISRQNSNNQQIIDTLEKELAERMKNRNAEVEKENFVIQELKNHLHQVLKFSENSLVRTKQEAEKQQKADFRASQARVAKIQQEILQLQSQFYNLVMENREAEQALR--KVPREAA 327

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BLAST of IQ domain-containing protein D vs. Ensembl Human
Match: IQCD (IQ motif containing D [Source:HGNC Symbol;Acc:HGNC:25168])

HSP 1 Score: 62.7734 bits (151), Expect = 5.212e-10
Identity = 74/286 (25.87%), Postives = 128/286 (44.76%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTAL---TTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKK 1062
            D  K L  +R KLTT+E +RIMS+LD  I + E++T +  V +N EDM  +L        D  + ++   D+    L+ +R +++  +Q      +EQ  A E+ W             R+    I    S                +   L +++K +T+ +     +NP A   L   T G       RS     FI  L++L+  L  +L+T+P E  +   +L+ ++ +   NQ II+ LE EL  A+  K     E+ + +      +H+ EK+S E +++
Sbjct:   32 DPLKPLVLSRTKLTTIEAKRIMSILDEAIYKVELVTLLSYVASNREDMEGMLGE------DVMRAVREHEDLCQVLLENVRCLKEKERQ-----LQEQKEAEEEGWL------------RDRLLSIELQKS----------------SLSPLMQQIKDSTKNVLRLLLSNPQAARLLQMQTQG-------RSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDISRQNSNNQQIIDTLEKEL--AERMKNRNAEEELEDLDA----VHREEKISLEELRR 265

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BLAST of IQ domain-containing protein D vs. Ensembl Zebrafish
Match: iqcd (IQ motif containing D [Source:ZFIN;Acc:ZDB-GENE-060526-200])

HSP 1 Score: 115.931 bits (289), Expect = 1.436e-27
Identity = 119/433 (27.48%), Postives = 215/433 (49.65%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKL-KFATRCLFIGFKANPAALTAL------TTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            D  K + P+RK L+  E + I+ VLD CI             + +E  S++ T     LL + + + L L+      + ++ +++++K E E+YQ   S+A +                                    N + N ++  +  S KL + + R +    +A P     L      TTGE         G     + L +L++++  RL+TTP E+ E+   + +++++  ANQ +I  LE E+  A ++K  +IS  N+ + + +  +HQ+ K  +E + +T+ + E+Q   D K S+    +LQQE  Q +T+ NN +   R  E+++R  K K+E+ +E  +Q YD  + + QTE E +   + E++ +L E+E+RF T++ EY +IMEE++ A+E R    RE +I ++A   IQA+WR +
Sbjct:   16 DSPKTINPSRKVLSCREAKLILGVLDECI-------------HQMETASLLPT-----LLKSSEALSLSLEE-----EVVKALKEHQKLE-EKYQ---SIALDG-----------------------------------NHDQNELQVEKAKSAKLVQDSFRKIIRLLRATPTTKVVLKRIEPNTTGEM--------GSQKIRNGLCELREVVLERLLTTPAEEKESRKMMLEVSQRHSANQKLIEALEKEVAEANKNKDAEISTLNNKVLQLRRTLHQMGKGLEEFVMRTQQDAEKQSHSDRKTSDGKRARLQQEASQLRTQLNNAIKASRGREQDLRKEKYKEETEIENLIQKYDAEIGEKQTELEEMTRMHEEDQMELTELEKRFDTLDLEYSQIMEERQEAQELREQQERERQIQSQAATVIQAYWRGF 378

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BLAST of IQ domain-containing protein D vs. Ensembl Xenopus
Match: iqcd (IQ motif containing D [Source:NCBI gene;Acc:100216273])

HSP 1 Score: 140.584 bits (353), Expect = 7.452e-36
Identity = 129/423 (30.50%), Postives = 218/423 (51.54%), Query Frame = 1

Query:  223 KALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            K LE  RKKLT++ETQR++SVLD  IK+ E+++     ++N+E   IVL  +L+  L  ++ ++  +++ +++L +  G         EEY        ED     K+T+                           ++S++I  +  + + ++ + R     F +NP A  AL   E      R P     I  + +++  L   L+T+P EQ E   YL  +  + K N+ ++  LE ELK     +  +IS+KN+ I+  +  +HQ+EKLS+  +K+   E E Q++ D + SE  C K+  E+ Q +++ ++ +SE R  E  MR  K K E+ +E  +Q YDT M + Q E E ++ +Y  EK QL E++E+   +EEEY++IMEE+R+A+ +     RE     +A   IQA W+ Y
Sbjct:   39 KMLEQGRKKLTSIETQRVISVLDETIKKLELVSMFQHAVDNLEQYKIVLGSELVGALREHQRLQDNMNLQLTRLHSKEGE--------EEYS-----IVED-----KNTK---------------------------EQSDVI--FARIRQGIQSSIRNTLRLFVSNPPASKALR-AEGHL---RDPAYQELIQTMSEMRGFLFEFLLTSPLEQTEKMRYLHDITIRNKKNRELLLTLEEELKTVVLDRDTEISKKNEIIRHLKVNLHQLEKLSESQVKRIMQEAETQQKSDCRTSEGKCSKIHHELQQLRSQLSSTISENREIELTMRKKKYKIETEIENWIQKYDTDMGEKQDELEELEAEYNLEKAQLAEVQEKLAVMEEEYIQIMEERRLAKLRMEEEERELANKNRAATVIQAHWKGY 410

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BLAST of IQ domain-containing protein D vs. Ensembl Mouse
Match: Iqcd (IQ motif containing D [Source:MGI Symbol;Acc:MGI:1922982])

HSP 1 Score: 124.79 bits (312), Expect = 2.455e-30
Identity = 80/239 (33.47%), Postives = 142/239 (59.41%), Query Frame = 1

Query:  775 RSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            RSPG    +  L++L+  L  +L+T+P E  E + +++ ++ + + NQ +I+DL+ EL    ++K+ ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q+++D + S+    K QQ+I   + +Y+N++ E R  E+ +R  K K E+ +E  +Q YD  M + Q EYE ++  + EEK QL E+ ER   + EE+ +I  E  I  +KR  A RE   + +A   IQA W+ Y
Sbjct:  173 RSPGAQCLLDGLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSERNQEVIDDLQAELANVLKNKESEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDFRASQVRLAKTQQDILALRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMGEKQDEYEDLESIHKEEKLQLEELRERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAVWKGY 411

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BLAST of IQ domain-containing protein D vs. Ensembl Mouse
Match: Iqcd (IQ motif containing D [Source:MGI Symbol;Acc:MGI:1922982])

HSP 1 Score: 89.3521 bits (220), Expect = 1.204e-18
Identity = 70/239 (29.29%), Postives = 124/239 (51.88%), Query Frame = 1

Query:  775 RSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            RSPG    +  L++L+  L  +L+T+P E  E + +++ ++ + + NQ +I+DL+ EL    ++K+ ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q+++D + S+                                  K K E+ +E  +Q YD  M + Q EYE ++  + EEK QL E+ ER   + EE+ +I  E  I  +KR  A RE   + +A   IQA W+ Y
Sbjct:  173 RSPGAQCLLDGLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSERNQEVIDDLQAELANVLKNKESEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDFRASQ---------------------------------KKYKVETEIENWIQKYDMEMGEKQDEYEDLESIHKEEKLQLEELRERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAVWKGY 378

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BLAST of IQ domain-containing protein D vs. UniProt/SwissProt
Match: sp|Q96DY2|DRC10_HUMAN (Dynein regulatory complex protein 10 OS=Homo sapiens OX=9606 GN=IQCD PE=1 SV=2)

HSP 1 Score: 143.665 bits (361), Expect = 3.400e-36
Identity = 127/429 (29.60%), Postives = 216/429 (50.35%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTAL---TTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            D  K L  +R KLTT+E +RIMS+LD  I + E++T +  V +N EDM  +L        D  + ++   D+    L+ +R +++  +Q      +EQ  A E+ W   +    E             S SP                   L +++K +T+ +     +NP A   L   T G       RS     FI  L++L+  L  +L+T+P E  +   +L+ ++ +   NQ II+ LE EL    +++  ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q++ D + S++   K+QQEI Q ++++ N++ E R  E+ +R  K K E+ +E  +Q YDT M + Q E E +D  + EEK  L E+  R K +  E+ +I EE+ I  +KR  A +E   + +A   IQA W+ Y
Sbjct:   32 DPLKPLVLSRTKLTTIEAKRIMSILDEAIYKVELVTLLSYVASNREDMEGMLGE------DVMRAVREHEDLCQVLLENVRCLKEKERQ-----LQEQKEAEEEGWLRDRLLSIE---------LQKSSLSP-------------------LMQQIKDSTKNVLRLLLSNPQAARLLQMQTQG-------RSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDISRQNSNNQQIIDTLEKELAERMKNRNAEVEKENFVIQELKNHLHQVLKFSENSLVRTKQEAEKQQKADFRASQARVAKIQQEILQLQSQFYNLVMENREAEQALRKKKYKVETEIENWIQKYDTEMGEKQEELEDLDAVHREEKISLEELRRRHKVLVGEFAQIREEREINSKKRMEAEQEMVRMVRAATLIQALWKGY 414

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BLAST of IQ domain-containing protein D vs. UniProt/SwissProt
Match: sp|Q17QH9|DRC10_BOVIN (Dynein regulatory complex protein 10 OS=Bos taurus OX=9913 GN=IQCD PE=2 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 1.703e-32
Identity = 119/428 (27.80%), Postives = 214/428 (50.00%), Query Frame = 1

Query:  223 KALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRK--QEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAA---LTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            KAL P R KLTT+ET+RIMSVLD  I + E+++ +    +  +      T + +   D  K ++   D+  + LD +  +++  +  QE E+++ E                               ++  E +      +S L    +E+ E  K   R L     +NP A   L A T G       RS     FI  L++L+  L  +L+T+P E  +   +++ +  + + +Q II+ LE EL A   ++  ++ ++N  I++ +  +HQV + S+ ++ +TK E E+Q++ D + S++    +QQEI   ++++ N++ E R  E+ +R  K K E+ +E  +Q YD+ M + Q EYE +D  + EE+ QL E+++R   + EE+ +I  E+ I  +KR    +E   + +A   IQA W+ Y
Sbjct:   35 KALTPARSKLTTIETKRIMSVLDETIHKVELVSLLSHAASESK------TSEGMLGPDIAKAVREHEDLCQALLDRVSYLQEEERKLQEAEDFEDE-------------------------------AWFRERLFAMDLQKSQLPPLMQEIKESTKNVVRLLL----SNPQAASLLQAQTLG-------RSKEAQCFIDSLVELRGFLFEKLLTSPMEARDKIQFIQDITRRNRRHQEIIDTLENELAACVRNRNAEVEKENFVIQELKNHLHQVLRFSENSLLRTKQEAEKQQKADFRASQARVATVQQEILVLQSQFYNLVMENRDTEQALRKKKYKVETEIENWIQKYDSEMSEKQDEYEELDIIHKEEQLQLEELKKRHDVLVEEFSQIQAEREILTKKRLEDEQEMVRMVRAATLIQALWKGY 414

[Close]

BLAST of IQ domain-containing protein D vs. UniProt/SwissProt
Match: sp|Q5XIR6|DRC10_RAT (Dynein regulatory complex protein 10 OS=Rattus norvegicus OX=10116 GN=Iqcd PE=2 SV=2)

HSP 1 Score: 125.176 bits (313), Expect = 1.191e-29
Identity = 81/239 (33.89%), Postives = 144/239 (60.25%), Query Frame = 1

Query:  775 RSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            RSPG    ++ L++L+  L  +L+T+P E  E + +++ ++ + K NQ II+ L+ EL    ++K+ ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q+++D + S++   K QQ+I   + +Y+N++ E R  E+ +R  K K E+ +E  +Q YD  M + Q EYE ++  + EEK QL E++ER   + EE+ +I  E  I  +KR  A RE   + +A   IQA W+ Y
Sbjct:  173 RSPGAQCLLTSLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSKRNQEIIDALQAELAEVLKNKEAEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDYRASQARQAKTQQDILALRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMNEKQEEYEDLETIHKEEKLQLEELKERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAMWKGY 411

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BLAST of IQ domain-containing protein D vs. UniProt/SwissProt
Match: sp|Q9D3V1|DRC10_MOUSE (Dynein regulatory complex protein 10 OS=Mus musculus OX=10090 GN=Iqcd PE=2 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 1.717e-29
Identity = 80/239 (33.47%), Postives = 142/239 (59.41%), Query Frame = 1

Query:  775 RSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            RSPG    +  L++L+  L  +L+T+P E  E + +++ ++ + + NQ +I+DL+ EL    ++K+ ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q+++D + S+    K QQ+I   + +Y+N++ E R  E+ +R  K K E+ +E  +Q YD  M + Q EYE ++  + EEK QL E+ ER   + EE+ +I  E  I  +KR  A RE   + +A   IQA W+ Y
Sbjct:  173 RSPGAQCLLDGLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSERNQEVIDDLQAELANVLKNKESEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDFRASQVRLAKTQQDILALRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMGEKQDEYEDLESIHKEEKLQLEELRERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAVWKGY 411

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BLAST of IQ domain-containing protein D vs. UniProt/SwissProt
Match: sp|Q4R8Y5|DRC10_MACFA (Dynein regulatory complex protein 10 OS=Macaca fascicularis OX=9541 GN=IQCD PE=2 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 1.052e-28
Identity = 88/275 (32.00%), Postives = 158/275 (57.45%), Query Frame = 1

Query:  667 LSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            L++++K +T+ +     +NP A   L    +     RS     FI  L++L+  L  +L+T+P E  +   +++ +N +   NQ II+ LE EL    + +  ++ ++N  I++ +  +HQV K S+ ++ +TK E E+Q++ D + S++   K+QQEI Q ++++ N++ E R  E+ +R  K K E+ +E  +Q YDT M + Q E E ++  + EEK  L E++ R K + EE+++I EE+ I  +KR  A +E   + +A   IQAFW+ Y
Sbjct:  121 LTQQIKDSTKNVLRLLLSNPQAARLLQMQTQS----RSAEAQNFIDSLIELRGFLFEKLVTSPMEARDKAQFIQDINRQNSNNQQIIDTLENELAERMKKRNAEVEKENFVIQELKNHLHQVLKFSENSLLRTKQEAEKQQKADFRASQARVAKIQQEILQLQSQFYNLVMENREAEQALRKKKYKVETEIENWIQKYDTEMGEKQEELEDLEAVHKEEKIALEELKRRHKVLVEEFVQIREEREINSKKRMEAEQEMVRMVRAATLIQAFWKGY 391

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BLAST of IQ domain-containing protein D vs. TrEMBL
Match: A0A267EP97 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027354g1 PE=4 SV=1)

HSP 1 Score: 251.906 bits (642), Expect = 9.853e-74
Identity = 174/422 (41.23%), Postives = 264/422 (62.56%), Query Frame = 1

Query:  229 LEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLA-SEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            LEP RKKLTTLETQRIM V+ +  K+ E++ A+P++L N++D  IVL R+L  LL  +  +  + D+V +KLD I     +RK     Y+  + +A +EDFW+  +   PE+    +E   ++ S   EE+   Q   + L      L  +L+F+ R L   F++NP A+TA+    +  K+K        + ++  L+DI+ +RLMTTP E+ +  +YL +M+E+ +    +I  LE EL AA   K+ ++ +KND I+K Q++IH VEK ++E+IK  + E E+Q++ D KNSE    KL QE  Q +T+ +N+++E R  E+++R+ K K E+ +E  +  YD+ M   Q EYE VD  YTEEK QL E+EERFKT+EEEYL+IMEE+R+AEE+R AA  E +++  A  TIQ+FWRSY
Sbjct:   52 LEPARKKLTTLETQRIMGVMIDGSKRVELLAALPALLRNLDDFQIVLGRELTALLVEHGNLSRQFDLVSAKLDVI----HDRK-----YEAPKPVALTEDFWS--QEAEPEA----DEAPVVTQSK--EELLPLQ---AELEAEAASLLPRLQFSARVLLRAFRSNPPAVTAVL---QSAKLKPQTETKEMLDRMEHLRDIMVVRLMTTPVEKQDKLTYLHEMSERERQQAEVIKKLEAELSAATADKEAEVKKKNDVIRKIQSDIHHVEKYAEESIKNIRSEAEKQQQTDSKNSEGKVHKLTQERNQLRTQLDNLIAEHRDSEQQLRSKKFKLETEIENIISKYDSEMGTRQEEYEDVDAAYTEEKKQLSELEERFKTLEEEYLQIMEERRVAEERRRAAEHEMQMMISAATTIQSFWRSY 450

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BLAST of IQ domain-containing protein D vs. TrEMBL
Match: A0A1I8HTE4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 1.009e-73
Identity = 174/422 (41.23%), Postives = 264/422 (62.56%), Query Frame = 1

Query:  229 LEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLA-SEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            LEP RKKLTTLETQRIM V+ +  K+ E++ A+P++L N++D  IVL R+L  LL  +  +  + D+V +KLD I     +RK     Y+  + +A +EDFW+  +   PE+    +E   ++ S   EE+   Q   + L      L  +L+F+ R L   F++NP A+TA+    +  K+K        + ++  L+DI+ +RLMTTP E+ +  +YL +M+E+ +    +I  LE EL AA   K+ ++ +KND I+K Q++IH VEK ++E+IK  + E E+Q++ D KNSE    KL QE  Q +T+ +N+++E R  E+++R+ K K E+ +E  +  YD+ M   Q EYE VD  YTEEK QL E+EERFKT+EEEYL+IMEE+R+AEE+R AA  E +++  A  TIQ+FWRSY
Sbjct:   41 LEPARKKLTTLETQRIMGVMIDGSKRVELLAALPALLRNLDDFQIVLGRELTALLVEHGNLSRQFDLVSAKLDVI----HDRK-----YEAPKPVALTEDFWS--QEAEPEA----DEAPVVTQSK--EELLPLQ---AELEAEAASLLPRLQFSARVLLRAFRSNPPAVTAVL---QSAKLKPQTETKEMLDRMEHLRDIMVVRLMTTPVEKQDKLTYLHEMSERERQQAEVIKKLEAELSAATADKEAEVKKKNDVIRKIQSDIHHVEKYAEESIKNIRSEAEKQQQTDSKNSEGKVHKLTQERNQLRTQLDNLIAEHRDSEQQLRSKKFKLETEIENIISKYDSEMGTRQEEYEDVDAAYTEEKKQLSELEERFKTLEEEYLQIMEERRVAEERRRAAEHEMQMMISAATTIQSFWRSY 439

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BLAST of IQ domain-containing protein D vs. TrEMBL
Match: A0A1I8IRL0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 1.171e-73
Identity = 174/422 (41.23%), Postives = 264/422 (62.56%), Query Frame = 1

Query:  229 LEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLA-SEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            LEP RKKLTTLETQRIM V+ +  K+ E++ A+P++L N++D  IVL R+L  LL  +  +  + D+V +KLD I     +RK     Y+  + +A +EDFW+  +   PE+    +E   ++ S   EE+   Q   + L      L  +L+F+ R L   F++NP A+TA+    +  K+K        + ++  L+DI+ +RLMTTP E+ +  +YL +M+E+ +    +I  LE EL AA   K+ ++ +KND I+K Q++IH VEK ++E+IK  + E E+Q++ D KNSE    KL QE  Q +T+ +N+++E R  E+++R+ K K E+ +E  +  YD+ M   Q EYE VD  YTEEK QL E+EERFKT+EEEYL+IMEE+R+AEE+R AA  E +++  A  TIQ+FWRSY
Sbjct:   41 LEPARKKLTTLETQRIMGVMIDGSKRVELLAALPALLRNLDDFQIVLGRELTALLVEHGNLSRQFDLVSAKLDVI----HDRK-----YEAPKPVALTEDFWS--QEAEPEA----DEAPVVTQSK--EELLPLQ---AELEAEAASLLPRLQFSARVLLRAFRSNPPAVTAVL---QSAKLKPQTETKEMLDRMEHLRDIMVVRLMTTPVEKQDKLTYLHEMSERERQQAEVIKKLEAELSAATADKEAEVKKKNDVIRKIQSDIHHVEKYAEESIKNIRSEAEKQQQTDSKNSEGKVHKLTQERNQLRTQLDNLIAEHRDSEQQLRSKKFKLETEIENIISKYDSEMGTRQEEYEDVDAAYTEEKKQLSELEERFKTLEEEYLQIMEERRVAEERRRAAEHEMQMMISAATTIQSFWRSY 439

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BLAST of IQ domain-containing protein D vs. TrEMBL
Match: V4A4P4 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_83213 PE=4 SV=1)

HSP 1 Score: 230.72 bits (587), Expect = 1.869e-66
Identity = 151/426 (35.45%), Postives = 253/426 (59.39%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            D ++ALEP+RKK++T+E QR+MSV +  I++ EIIT +P ++ N++   I L   L  LL ++++I+   + + ++LD                             H+    P  + + N    +S     +  E        +I+    ++++L F+ + +   F+ NP+A  ++  GE  ++++    + M +S + +L+DIL  +L+TTP E+ E  +YL +++++ + N  II  LE E KA  E K+E+I +KN+ I++ QA++HQ+EK S+E+I++ K E E+Q+  D KNSE   QKLQQ+I   +T++ ++ +E R  E+E+R  K K E+ +E  +Q +D  M + Q EYE +DE YTEEK QL+E+EERFKT+E EY +I EE+R+A E+R  A +E   + +A  TIQAFWRS+
Sbjct:    1 DPSRALEPSRKKISTIEAQRVMSVFEETIRRVEIITLLPHIIENLDRFRISLGSDLADLLQHHQVIQESYNEIRAELD----------------------------KHLAKRTPTQSAKSN----VSRKTDAQLEE--------IIRNLSLVAQQLSFSCKNILRAFQINPSACNSVL-GE--FRVRNENCNEMVVS-MQELRDILMGKLLTTPEEEKERMAYLTEISQRERYNAGIIQKLEAEYKAGMEDKEEEIRKKNEVIRRLQADLHQIEKFSEEHIRRVKAEAEKQETSDVKNSEGKRQKLQQDINHLRTQFQSMTAEHRENEQELRRRKFKVETEVENWIQKFDQDMGERQDEYEEIDEIYTEEKKQLHELEERFKTLEAEYKQIQEERRLARERREKAEQEMARMVRASTTIQAFWRSF 382

[Close]

BLAST of IQ domain-containing protein D vs. TrEMBL
Match: A0A1I8HTQ3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 229.18 bits (583), Expect = 1.919e-65
Identity = 166/422 (39.34%), Postives = 253/422 (59.95%), Query Frame = 1

Query:  229 LEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLA-SEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            LEP RKKLTTLETQRIM V+ +  K+ E++ A+P++L N++D  IVL R+L  LL  +  +  + D+V +KLD I     +RK     Y+  + +A +EDFW+  +   PE+    +E   ++ S   EE+   Q   + L      L  +L+F+ R L   F++NP A+TA+    +  K+K        + ++  L+DI+ +RLMTTP E+ +  +YL +M+E+ +    +I  LE EL AA   K+ ++ +KND I+K Q++IH VEK ++E+IK  + E E+Q++ D KNSE    KL QE  Q +T+ +N+++E R  E+++R+                       + EYE VD  YTEEK QL E+EERFKT+EEEYL+IMEE+R+AEE+R AA  E +++  A  TIQ+FWRSY
Sbjct:   41 LEPARKKLTTLETQRIMGVMIDGSKRVELLAALPALLRNLDDFQIVLGRELTALLVEHGNLSRQFDLVSAKLDVI----HDRK-----YEAPKPVALTEDFWS--QEAEPEA----DEAPVVTQSK--EELLPLQ---AELEAEAASLLPRLQFSARVLLRAFRSNPPAVTAVL---QSAKLKPQTETKEMLDRMEHLRDIMVVRLMTTPVEKQDKLTYLHEMSERERQQAEVIKKLEAELSAATADKEAEVKKKNDVIRKIQSDIHHVEKYAEESIKNIRSEAEKQQQTDSKNSEGKVHKLTQERNQLRTQLDNLIAEHRDSEQQLRSK----------------------EEEYEDVDAAYTEEKKQLSELEERFKTLEEEYLQIMEERRVAEERRRAAEHEMQMMISAATTIQSFWRSY 417

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BLAST of IQ domain-containing protein D vs. Ensembl Cavefish
Match: iqcd (IQ motif containing D [Source:NCBI gene;Acc:103032804])

HSP 1 Score: 82.0333 bits (201), Expect = 2.689e-16
Identity = 73/222 (32.88%), Postives = 124/222 (55.86%), Query Frame = 1

Query:  826 ILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            +L  RL  TP E+      +++   +  +NQ ++  LE E  AA + + ++IS  N  I+  ++ I + EK SD+ + + + E ER  E  +K SE    +LQ+E+ Q K +  N++ + R  E  +R    K E+ ++  ++ YD  M + QT+ E + + + EE  +L E++E +   E E+ KIMEE RI +E+R    RE E+ ++A I IQAFWR +
Sbjct:  162 VLLKRLFMTPMEERVRIQRMQEDTLRHNSNQKVLATLEKEAAAAVKDRDKEISWMNKVIQWLRSSILKTEKCSDDFVVRKQKEAERHDESVQKTSELKQTRLQEEVNQLKVQLKNLIIQHRDAELALRKKSYKVETEVQNWIEKYDAEMGEKQTKLEEITQIHEEEMAELSELQEYYAVRELEFSKIMEEHRIEQERRDEEEREREVQSRAAIIIQAFWRGW 383

[Close]

Query:  826 ILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            +L  RL  TP E+      +++   +  +NQ ++  LE E  AA + + ++IS  N  I+  ++ I + EK SD+ + + + E ER  E  +K SE    +LQ+E+ Q K +  N++ + R  E  +R    K E+ ++  ++ YD  M + QT+ E + + + EE  +L E++E +   E E+ KIMEE RI +E+R    RE E+ ++A I IQAFWR +
Sbjct:  162 VLLKRLFMTPMEERVRIQRMQEDTLRHNSNQKVLATLEKEAAAAVKDRDKEISWMNKVIQWLRSSILKTEKCSDDFVVRKQKEAERHDESVQKTSELKQTRLQEEVNQLKVQLKNLIIQHRDAELALRKKSYKVETEVQNWIEKYDAEMGEKQTKLEEITQIHEEEMAELSELQEYYAVRELEFSKIMEEHRIEQERRDEEEREREVQSRAAIIIQAFWRGW 383

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BLAST of IQ domain-containing protein D vs. Ensembl Cavefish
Match: ENSAMXT00000008878.2 (IQ domain-containing protein D-like [Source:NCBI gene;Acc:107196985])

HSP 1 Score: 55.8398 bits (133), Expect = 7.087e-8
Identity = 64/233 (27.47%), Postives = 119/233 (51.07%), Query Frame = 1

Query:  820 KDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEME-------ERFKTIEE-EYLXXXXXXXXXXXXXXXXXXXXXXLTK-AVITIQAFWRSY 1491
            +  L  +L  TP E+  +   +R+   ++++NQ  +  LE E+ A  E   ++IS  +  I   +  + ++EK +++ + + K   ER+ E  +K S+    ++ +EI Q + +  +++  G   E+E R    K    +E  +  YDT + Q QTE         EE TQLYEME       +++  + E EYL+++E +RI +E R    RE  +  + A + +Q+FW+ +
Sbjct:  159 RSFLLQQLYMTPREERLHLQQMREAPLRYESNQEALAALEREMAATIEAMDKEISWLSKVIDWLKRSMDRIEKRAEDFVAQKKNNAERRNESLQKTSQLKQAQILEEISQLELQLESLIKRGLEDEREQRKRCTKLRGMVEDWIDVYDTEIEQKQTEL--------EETTQLYEMEMAELSDLQKYHAVREVEYLQVVERRRIEKELREKEERERGLRIRAAAVILQSFWKGW 383

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BLAST of IQ domain-containing protein D vs. Ensembl Nematostella
Match: EDO44929 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUM4])

HSP 1 Score: 152.525 bits (384), Expect = 4.134e-41
Identity = 130/426 (30.52%), Postives = 220/426 (51.64%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            D  K L+P RKKL+++E+QR++SVLD+ I++ EI + +P +  N+E  S++L  +L  L+  +  ++      +SK                 ++ EQ  A        +S  P+++                                  LS  L+ + R L   F  NP A+TA+ T   +    RS   +  I +L  ++ +L  RL+TTP+E  +   YL  + E+ K +  + + L+ EL+ A + +  +I+++N+ I++ + +I  V+K ++E  K+   E  +Q   + KNS+    KLQQE+ + K +     +  R  E  +R  K K E+ +E  +Q +D  M + Q E++ +D  YTEEK QL E+EERFKT+E EY++I+EE+RIA+EK  AA RE  +  +A   IQA WR++
Sbjct:    6 DPLKVLDPARKKLSSVESQRVISVLDDTIRRIEIGSLLPFIAENLERYSVILGSELSLLISEHDKLQHAYQKAVSK-----------------FELEQKRA--------RSASPQTS----------------------------------LSMMLQQSLRTLLRQFSRNPTAMTAIRTERHE----RSFESNSMIDELSAIRAVLFERLLTTPSELKDRDKYLMAVAERQKRSSQMADKLQDELQNAIDDRDNEIAKRNEIIRRLKNDIFNVDKNAEEQNKRIVTEASKQDAAEMKNSDGKKAKLQQELIETKKKLEAQTAAHRESELALRKRKYKIETEVENWIQKFDNDMGERQDEFDALDVVYTEEKKQLQELEERFKTLEAEYVQIVEERRIAKEKAEAAERELNLKIRAARLIQAMWRAH 368

[Close]

BLAST of IQ domain-containing protein D vs. Ensembl Nematostella
Match: EDO49121 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGV7])

HSP 1 Score: 63.5438 bits (153), Expect = 7.652e-11
Identity = 70/271 (25.83%), Postives = 127/271 (46.86%), Query Frame = 1

Query:  679 LKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            LKF+   +   FK NP A+  +       K K  P     +  + QL  ++  RL+TTPTE+ +   Y+  +  + +        L+   + A   K+ ++S++N  I + ++E+  +  ++ E  +KT  +  +Q   + K SE+    +++++  K+    +   E R  E  +R    K  + +   +Q YD  M   Q     + + Y EEK  L EME+ F+ +E +Y  I+EE+R+A E      +E      A + IQA WR +
Sbjct:  100 LKFSLMDILRHFKKNPKAVEVILGS----KHKTDPVHQELLQFMTQLSMVMKERLLTTPTEEFDRKGYIVDILTRERKTNAAKGRLQARCREAVRDKEHEVSKRNTIIAQLKSELSMINNVTHEAQRKTLSDAAKQCSTEIKTSENKKMTIREDMITKRKHVRDRRREHREEETVLRKRAFKIGTEVYNWIQKYDADMGAKQA----IAKLYEEEKQDLREMEQEFQNMEAKYNAILEERRLAAEAEKKRQQELVQRNYAAVRIQAVWRGF 362

HSP 2 Score: 48.9062 bits (115), Expect = 3.183e-6
Identity = 25/63 (39.68%), Postives = 38/63 (60.32%), Query Frame = 1

Query:  214 DCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNY 402
            D  + LEP +K L  LE+QRIM+VL++ I + E+ T +  V+   E   +VL   L+ LLD +
Sbjct:    1 DPCRILEPNKKNLHMLESQRIMAVLEDTILRLELATILGHVMRERERFGVVLGTDLVELLDYH 63

[Close]

BLAST of IQ domain-containing protein D vs. Planmine SMEST
Match: SMESG000017912.1 (SMESG000017912.1)

HSP 1 Score: 863.218 bits (2229), Expect = 0.000e+0
Identity = 451/457 (98.69%), Postives = 452/457 (98.91%), Query Frame = 1

Query:  121 RQTTISKKSDFNKDAELKSSVSYKNASNINIDCTKALEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            RQTTISKKSDFNKD ELK SVSYKNASNI IDCTKALEPTRKKLTTLETQRIM VLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIE+FQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDIL LRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLKIMEEKRIAEEKRAAAAREEEILTKAVITIQAFWRSY
Sbjct:   10 RQTTISKKSDFNKDTELKLSVSYKNASNIKIDCTKALEPTRKKLTTLETQRIMGVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVKSTRPESAGQRNEFGFISYSYSPEEIEKFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILTLRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLKIMEEKRIAEEKRAAAAREEEILTKAVITIQAFWRSY 466

[Close]

BLAST of IQ domain-containing protein D vs. Planmine SMEST
Match: SMESG000036536.1 (SMESG000036536.1)

HSP 1 Score: 147.902 bits (372), Expect = 1.317e-38
Identity = 127/429 (29.60%), Postives = 231/429 (53.85%), Query Frame = 1

Query:  229 LEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIE-EYQREQSLASEDFWT-----HVKSTRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKN--SESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            L+P  + L T+E++RI+ +LD+ IK   +I +  S++ ++ED + +L +QL  L  N+K   +    +  ++   +G  Q    ++E E Q++     EDFWT      +K    +SA   ++   ++       +E  +     L +  ++++  ++F  R + I F+ NP A+  +   ++ W+IK +      I  + QL+ +L  RL+TTP E++E   YL  + +K KA+Q++INDL+  L+  +  K++ I++ N  I   Q EI+++E      I   K+E + ++E+DE     E     L  ++   K +YN ++   R+ E E+R  K K E+  E  +  YD+ M + QT+++ +   Y  EK  L E+ + F+ +E+EYL+++EE+RIA+EKR A   E E L      IQ+FWR++
Sbjct:   29 LKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVN-------VEEIREKLPELEEKKKKMTPIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGKNEI--YKIEKKSEEELDEIRLAHEETKAMLTGQLNDLKVKYNELVERNRNNELEIRRRKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLEEQRIAKEKREAERAENEALVYWATVIQSFWRAW 448

[Close]

BLAST of IQ domain-containing protein D vs. Planmine SMEST
Match: SMESG000036536.1 (SMESG000036536.1)

HSP 1 Score: 117.857 bits (294), Expect = 4.600e-28
Identity = 129/452 (28.54%), Postives = 224/452 (49.56%), Query Frame = 1

Query:  229 LEPTRKKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIE-EYQREQSLASEDFWT-----HVKSTRPESAGQRNEFGFISYSYSPEEI-ERFQNDESNLIKTYEELSEKLKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLL----------------------QLKDILALRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKN--SESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLXXXXXXXXXXXXXXXXXXXXXXLTKAVITIQAFWRSY 1491
            L+P  + L T+E++RI+ +LD+ IK   +I +  S++ ++ED + +L +QL  L  N+K   +    +  ++   +G  Q    ++E E Q++     EDFWT      +K    +SA   ++   ++     EEI E+    E    K  ++  EK      C    F            G+ +  +K  P +S+  SK                        +L+ +L  RL+TTP E++E   YL  + +K KA+Q++INDL+  L+  +  K++ I++ N  I   Q EI+++E      I   K+E + ++E+DE     E     L  ++   K +YN ++   R+ E E+R  K K E+  E  +  YD+ M + QT+++ +   Y  EK  L E+ + F+ +E+EYL+++EE+RIA+EKR A   E E L      IQ+FWR++
Sbjct:   29 LKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVNV----EEIREKLPELEEKKKKVNQKQLEKPNAENLCYTGNFSIYDC------NGKFNLSVKDDPNNSILRSKYSYCIQKQSPCRKLCHETQRDMANKLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGKNEI--YKIEKKSEEELDEIRLAHEETKAMLTGQLNDLKVKYNELVERNRNNELEIRRRKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLEEQRIAKEKREAERAENEALVYWATVIQSFWRAW 468

The following BLAST results are available for this feature:

BLAST of IQ domain-containing protein D vs. Ensembl Human
BLAST of IQ domain-containing protein D vs. Ensembl Celegans
BLAST of IQ domain-containing protein D vs. Ensembl Fly
BLAST of IQ domain-containing protein D vs. Ensembl Zebrafish
BLAST of IQ domain-containing protein D vs. Ensembl Xenopus
BLAST of IQ domain-containing protein D vs. Ensembl Mouse
BLAST of IQ domain-containing protein D vs. UniProt/SwissProt
BLAST of IQ domain-containing protein D vs. TrEMBL
BLAST of IQ domain-containing protein D vs. Ensembl Cavefish
BLAST of IQ domain-containing protein D vs. Ensembl Sea Lamprey
BLAST of IQ domain-containing protein D vs. Ensembl Yeast
BLAST of IQ domain-containing protein D vs. Ensembl Nematostella
BLAST of IQ domain-containing protein D vs. Ensembl Medaka
BLAST of IQ domain-containing protein D vs. Planmine SMEST

BLAST of IQ domain-containing protein D vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3


Match Name	E-value	Identity	Description
IQCD	7.079e-37	29.60	IQ motif containing D [Source:HGNC Symbol;Acc:HGNC...	[more]
IQCD	2.248e-24	27.33	IQ motif containing D [Source:HGNC Symbol;Acc:HGNC...	[more]
IQCD	5.212e-10	25.87	IQ motif containing D [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of IQ domain-containing protein D vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IQ domain-containing protein D vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IQ domain-containing protein D vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
iqcd	1.436e-27	27.48	IQ motif containing D [Source:ZFIN;Acc:ZDB-GENE-06...	[more]

BLAST of IQ domain-containing protein D vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
iqcd	7.452e-36	30.50	IQ motif containing D [Source:NCBI gene;Acc:100216...	[more]

BLAST of IQ domain-containing protein D vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Iqcd	2.455e-30	33.47	IQ motif containing D [Source:MGI Symbol;Acc:MGI:1...	[more]
Iqcd	1.204e-18	29.29	IQ motif containing D [Source:MGI Symbol;Acc:MGI:1...	[more]

BLAST of IQ domain-containing protein D vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q96DY2\|DRC10_HUMAN	3.400e-36	29.60	Dynein regulatory complex protein 10 OS=Homo sapie...	[more]
sp\|Q17QH9\|DRC10_BOVIN	1.703e-32	27.80	Dynein regulatory complex protein 10 OS=Bos taurus...	[more]
sp\|Q5XIR6\|DRC10_RAT	1.191e-29	33.89	Dynein regulatory complex protein 10 OS=Rattus nor...	[more]
sp\|Q9D3V1\|DRC10_MOUSE	1.717e-29	33.47	Dynein regulatory complex protein 10 OS=Mus muscul...	[more]
sp\|Q4R8Y5\|DRC10_MACFA	1.052e-28	32.00	Dynein regulatory complex protein 10 OS=Macaca fas...	[more]

BLAST of IQ domain-containing protein D vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267EP97	9.853e-74	41.23	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A1I8HTE4	1.009e-73	41.23	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8IRL0	1.171e-73	41.23	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
V4A4P4	1.869e-66	35.45	Uncharacterized protein (Fragment) OS=Lottia gigan...	[more]
A0A1I8HTQ3	1.919e-65	39.34	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of IQ domain-containing protein D vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
iqcd	2.689e-16	32.88	IQ motif containing D [Source:NCBI gene;Acc:103032...	[more]
iqcd	2.689e-16	32.88	IQ motif containing D [Source:NCBI gene;Acc:103032...	[more]
ENSAMXT00000008878.2	7.087e-8	27.47	IQ domain-containing protein D-like [Source:NCBI g...	[more]

BLAST of IQ domain-containing protein D vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IQ domain-containing protein D vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IQ domain-containing protein D vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO44929	4.134e-41	30.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49121	7.652e-11	25.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of IQ domain-containing protein D vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IQ domain-containing protein D vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000017912.1	0.000e+0	98.69	SMESG000017912.1	[more]
SMESG000036536.1	1.317e-38	29.60	SMESG000036536.1	[more]
SMESG000036536.1	4.600e-28	28.54	SMESG000036536.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30015703 ID=SMED30015703|Name=IQ domain-containing protein D|organism=Schmidtea mediterranea sexual|type=transcript|length=1658bp
TTTAAATATAAAATTTTATACATTTAATTTAAATACATTTATTACTTTAT
AATCTGCTGTATATTTTTATTTACTAATTACCTTTCTGATTTTATGTCTT
CTTTATCTGCTTCATTGTCTCGGCAAACGACGATAAGCAAAAAAAGTGAT
TTCAATAAAGATGCTGAGTTGAAGTCATCAGTAAGTTATAAAAATGCATC
GAATATAAACATCGACTGTACAAAAGCTCTTGAGCCCACCAGAAAAAAAT
TAACAACATTAGAAACCCAAAGAATTATGAGCGTGTTGGATAATTGTATA
AAACAAAGTGAAATAATAACCGCCATCCCGTCAGTTTTGAACAATATCGA
GGATATGTCAATCGTACTGACAAGGCAGCTGATATTCCTGTTGGACAATT
ACAAAATGATAAAATTGAAACTCGACGTTGTTATTTCAAAATTGGATGCG
ATTCGAGGAATCCGACAGAACAGAAAACAGGAAATCGAAGAATACCAACG
AGAGCAAAGTTTAGCCAGCGAAGATTTCTGGACCCATGTTAAATCAACTC
GACCAGAGTCTGCTGGTCAGAGAAATGAGTTCGGCTTCATCAGTTATTCC
TATAGTCCAGAGGAAATTGAAAGATTCCAAAACGACGAATCAAACCTCAT
CAAAACTTACGAAGAACTGAGTGAGAAACTTAAATTCGCCACGAGATGTT
TATTTATCGGATTCAAGGCCAATCCGGCAGCATTGACCGCTTTGACAACA
GGTGAAAAAGATTGGAAAATCAAAAGATCTCCTGGAGATTCGATGTTTAT
TAGCAAATTATTGCAACTAAAGGATATTTTAGCATTACGTTTGATGACAA
CTCCAACTGAGCAAAACGAAAATCATTCCTACCTTCGACAAATGAATGAA
AAGTTTAAGGCGAATCAAATGATTATTAATGATTTAGAAATAGAATTAAA
AGCTGCACAAGAACATAAAAAAGAACAAATATCTGAAAAAAATGATACAA
TTAAAAAATTCCAAGCGGAAATTCATCAAGTTGAAAAGCTATCCGACGAG
AATATTAAGAAAACAAAGTTGGAAATGGAAAGGCAGAAGGAAATAGATGA
GAAAAATAGCGAAAGTGTTTGCCAAAAATTACAACAAGAAATCTTTCAAA
AGAAAACAGAATACAACAACATTCTTTCGGAAGGTCGTTCGGGTGAGAAA
GAAATGAGAGCGAATAAAATAAAAAAAGAATCTGCATTGGAAACTAATCT
ACAAAATTATGACACCTTGATGAGACAAATACAAACTGAATATGAAATGG
TAGATGAACAATACACAGAGGAAAAGACACAATTATATGAAATGGAAGAA
AGATTTAAAACAATTGAAGAAGAATATCTAAAGATTATGGAAGAAAAACG
AATCGCTGAAGAAAAGAGGGCAGCAGCAGCCCGCGAAGAGGAAATCCTCA
CGAAAGCTGTGATAACAATTCAAGCTTTCTGGCGTTCTTATAAGGTGCGT
AAAGGAGTACGTGGAAGCACAAGAAAAGGAAAAGGCAAAGGCAAAAAGAA
GAAATAAATGATAATAATAATGACAATTTTATTTTGTTAATGAAGATAGA
TCCAATGCGTTATTTATCTTTCACTAAAATAAATATCAGGACAACTATTG
AAAAAAAA

protein sequence of SMED30015703-orf-1

>SMED30015703-orf-1 ID=SMED30015703-orf-1|Name=SMED30015703-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=488bp
MSSLSASLSRQTTISKKSDFNKDAELKSSVSYKNASNINIDCTKALEPTR
KKLTTLETQRIMSVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLL
DNYKMIKLKLDVVISKLDAIRGIRQNRKQEIEEYQREQSLASEDFWTHVK
STRPESAGQRNEFGFISYSYSPEEIERFQNDESNLIKTYEELSEKLKFAT
RCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILALRL
MTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKN
DTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEI
FQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEY
EMVDEQYTEEKTQLYEMEERFKTIEEEYLKIMEEKRIAEEKRAAAAREEE
ILTKAVITIQAFWRSYKVRKGVRGSTRKGKGKGKKKK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000106	ciliated epithelial cell
PLANA:0000418	head
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR042815	DRC10
IPR000048	IQ_motif_EF-hand-BS

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0003674	molecular_function

Vocabulary: **cellular component**
Term	Definition
GO:0005575	cellular_component

Vocabulary: **biological process**
Term	Definition
GO:0008150	biological_process

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 407..449
None	No IPR available	COILS	Coil	Coil	coord: 278..316
None	No IPR available	COILS	Coil	Coil	coord: 117..144
None	No IPR available	COILS	Coil	Coil	coord: 343..363
None	No IPR available	COILS	Coil	Coil	coord: 175..195
IPR000048	IQ motif, EF-hand binding site	SMART	SM00015	iq_5	coord: 451..473 e-value: 0.0051 score: 26.0
IPR000048	IQ motif, EF-hand binding site	PFAM	PF00612	IQ	coord: 453..471 e-value: 1.5E-5 score: 24.4
IPR000048	IQ motif, EF-hand binding site	PROSITE	PS50096	IQ	coord: 452..481 score: 8.462
IPR042815	Dynein regulatory complex protein 10	PANTHER	PTHR31598	FAMILY NOT NAMED	coord: 16..487

Main menu

IQ domain-containing protein D

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13

Owlery

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