Mitochondrial import receptor subunit TOM70

Overview


Name	Mitochondrial import receptor subunit TOM70
Smed ID	SMED30015700
Length (bp)	1970

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Mitochondrial import receptor subunit TOM70 (SMED30015700) t-SNE clustered cells

Violin plots show distribution of expression levels for Mitochondrial import receptor subunit TOM70 (SMED30015700) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Mitochondrial import receptor subunit TOM70 (SMED30015700) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015700

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30015700	SMESG000070025.1	dd_Smed_v4_10337_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015700	SMESG000070025.1	dd_Smed_v4_10337_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30015700	SMESG000070025.1	dd_Smed_v4_10337_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30015700	SMESG000070025.1	dd_Smed_v4_10337_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Human
Match: TOMM70 (translocase of outer mitochondrial membrane 70 [Source:HGNC Symbol;Acc:HGNC:11985])

HSP 1 Score: 158.303 bits (399), Expect = 1.661e-40
Identity = 135/492 (27.44%), Postives = 230/492 (46.75%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKS----CFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            D A   K KGN++F    +E AI+ Y  AI++CP +   D +  Y+N+A A  +L+   E   +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ KE+   +EP++ S + I  YF +F DD     +    +  E+       +++     Y    Q ++E      I +   EI++  K +++  LLR TFYLL      A  D  +VI    +    + NA+IKR ++ + +   L   + F  A DI+P  AD+++HRG       Q + A+ DF + + L  E  LA     F  Y   Y  +  S        FE +I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L   L L+ +AIE D K   +Y  +  I ++ G +EKAI+M  KAI  A++   M     + +   AQ  V++ + +
Sbjct:  112 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGL 603

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Human
Match: TTC1 (tetratricopeptide repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12391])

HSP 1 Score: 52.7582 bits (125), Expect = 7.882e-7
Identity = 44/140 (31.43%), Postives = 79/140 (56.43%), Query Frame = 2

Query:  305 QKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDST--DKSDSVDRMDNIVKNIAIERVKEEIL 718
            QKRR+E+  +K +GNE F   D+  A   Y  A+ +CP  F ++ ++L+ N+A A  + +    A+N+ +KA+++ P Y  A   R++++E   KL EAL D  + +  D +     ++  R+   ++    ER+KEE+L
Sbjct:  110 QKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERN-ERLKEEML 248

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Query:  305 QKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDST--DKSDSVDRMDNIVKNIAIERVKEEIL 718
            QKRR+E+  +K +GNE F   D+  A   Y  A+ +CP  F ++ ++L+ N+A A  + +    A+N+ +KA+++ P Y  A   R++++E   KL EAL D  + +  D +     ++  R+   ++    ER+KEE+L
Sbjct:  110 QKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERN-ERLKEEML 248

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Fly
Match: Tom70 (gene:FBgn0032397 transcript:FBtr0080310)

HSP 1 Score: 132.494 bits (332), Expect = 3.220e-32
Identity = 127/517 (24.56%), Postives = 228/517 (44.10%), Query Frame = 2

Query:  275 SQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIA-IERVKEEILKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLL--------LIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQG 1786
            S + EANN            K +GN  +    ++ AIK Y+ AI+ CP +   D A+ Y+N+A +   L+  +    +   +LE  P+Y  A+  R++  E    + E L D+TA    +    + ++   D ++K    ++  K    + PV+ S   +  Y ++FI DP  +      +     +   R    F+  +Y        E +++ +      +  L L+RGTF+LL      + +DF  +I N  + P+ +  A IKRA + +  +        F EA  +NP   D+++ R        Q + A+ +F+KA+ +   H +A V   + EY L+      +  +S    F+N I+  P+  E   +  +VL        AE    K +        LI   +  V+ +  DI         A+ LL +AIE DPK   +Y  L  + ++  +L +A+E+ EKA+ YA+++  +     ++    AQ+NV++   I +  V      G
Sbjct:   85 SPLKEANNY-----------KTEGNNCYRNGKYDEAIKFYDKAIDKCPKEHRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGMRNRVPVVPSACFVNTYTRSFIADPLQTMKVPAPKSDAPPKGFLRAHLAFLEEKYEEIIPACTEEIESSEAEAQYKVEAL-LMRGTFHLLCGSYVESQQDFDAIIANDYADPNLRAYAYIKRAALYIQLDQREKGIADFAEAERLNPENPDVYHQRAQILLLLEQIEPALAEFEKAVSIAPNHAIAFVQKCYAEYRLSLLAGDQRRLESVMHTFQNAIERFPSCVECYSLTAQVLADQQQFTQAEEYYKKAMVLAPTNPALIVHQAIMVLQWRGDINL-------AVQLLNKAIEVDPKCELAYETLGTVEVQRAQLTRAVELFEKALLYAKSQAELVHVYSLRNAAVAQINVTKKLGIDMNSVSAMAQSG 582

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Fly
Match: Tom70 (gene:FBgn0032397 transcript:FBtr0080309)

HSP 1 Score: 132.494 bits (332), Expect = 3.220e-32
Identity = 127/517 (24.56%), Postives = 228/517 (44.10%), Query Frame = 2

Query:  275 SQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIA-IERVKEEILKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLL--------LIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQG 1786
            S + EANN            K +GN  +    ++ AIK Y+ AI+ CP +   D A+ Y+N+A +   L+  +    +   +LE  P+Y  A+  R++  E    + E L D+TA    +    + ++   D ++K    ++  K    + PV+ S   +  Y ++FI DP  +      +     +   R    F+  +Y        E +++ +      +  L L+RGTF+LL      + +DF  +I N  + P+ +  A IKRA + +  +        F EA  +NP   D+++ R        Q + A+ +F+KA+ +   H +A V   + EY L+      +  +S    F+N I+  P+  E   +  +VL        AE    K +        LI   +  V+ +  DI         A+ LL +AIE DPK   +Y  L  + ++  +L +A+E+ EKA+ YA+++  +     ++    AQ+NV++   I +  V      G
Sbjct:   85 SPLKEANNY-----------KTEGNNCYRNGKYDEAIKFYDKAIDKCPKEHRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGMRNRVPVVPSACFVNTYTRSFIADPLQTMKVPAPKSDAPPKGFLRAHLAFLEEKYEEIIPACTEEIESSEAEAQYKVEAL-LMRGTFHLLCGSYVESQQDFDAIIANDYADPNLRAYAYIKRAALYIQLDQREKGIADFAEAERLNPENPDVYHQRAQILLLLEQIEPALAEFEKAVSIAPNHAIAFVQKCYAEYRLSLLAGDQRRLESVMHTFQNAIERFPSCVECYSLTAQVLADQQQFTQAEEYYKKAMVLAPTNPALIVHQAIMVLQWRGDINL-------AVQLLNKAIEVDPKCELAYETLGTVEVQRAQLTRAVELFEKALLYAKSQAELVHVYSLRNAAVAQINVTKKLGIDMNSVSAMAQSG 582

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Fly
Match: Tom70 (gene:FBgn0032397 transcript:FBtr0080311)

HSP 1 Score: 132.494 bits (332), Expect = 3.220e-32
Identity = 127/517 (24.56%), Postives = 228/517 (44.10%), Query Frame = 2

Query:  275 SQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIA-IERVKEEILKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLL--------LIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQG 1786
            S + EANN            K +GN  +    ++ AIK Y+ AI+ CP +   D A+ Y+N+A +   L+  +    +   +LE  P+Y  A+  R++  E    + E L D+TA    +    + ++   D ++K    ++  K    + PV+ S   +  Y ++FI DP  +      +     +   R    F+  +Y        E +++ +      +  L L+RGTF+LL      + +DF  +I N  + P+ +  A IKRA + +  +        F EA  +NP   D+++ R        Q + A+ +F+KA+ +   H +A V   + EY L+      +  +S    F+N I+  P+  E   +  +VL        AE    K +        LI   +  V+ +  DI         A+ LL +AIE DPK   +Y  L  + ++  +L +A+E+ EKA+ YA+++  +     ++    AQ+NV++   I +  V      G
Sbjct:   85 SPLKEANNY-----------KTEGNNCYRNGKYDEAIKFYDKAIDKCPKEHRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGMRNRVPVVPSACFVNTYTRSFIADPLQTMKVPAPKSDAPPKGFLRAHLAFLEEKYEEIIPACTEEIESSEAEAQYKVEAL-LMRGTFHLLCGSYVESQQDFDAIIANDYADPNLRAYAYIKRAALYIQLDQREKGIADFAEAERLNPENPDVYHQRAQILLLLEQIEPALAEFEKAVSIAPNHAIAFVQKCYAEYRLSLLAGDQRRLESVMHTFQNAIERFPSCVECYSLTAQVLADQQQFTQAEEYYKKAMVLAPTNPALIVHQAIMVLQWRGDINL-------AVQLLNKAIEVDPKCELAYETLGTVEVQRAQLTRAVELFEKALLYAKSQAELVHVYSLRNAAVAQINVTKKLGIDMNSVSAMAQSG 582

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Fly
Match: CG14894 (gene:FBgn0038428 transcript:FBtr0083314)

HSP 1 Score: 51.6026 bits (122), Expect = 7.791e-7
Identity = 41/111 (36.94%), Postives = 63/111 (56.76%), Query Frame = 2

Query:  302 LQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFD 634
            L   +++A  +K++GNE F  +D E A K Y  A++ICP    ++ AVLY N+A A  +LE N  A+++  KA+E+ P+Y      R+K++E   K  EAL D       D
Sbjct:   87 LTANKEKADKLKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLYGNRAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKPDEALEDYKKVTEID 197

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Fly
Match: CG14894 (gene:FBgn0038428 transcript:FBtr0337016)

HSP 1 Score: 51.6026 bits (122), Expect = 7.791e-7
Identity = 41/111 (36.94%), Postives = 63/111 (56.76%), Query Frame = 2

Query:  302 LQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFD 634
            L   +++A  +K++GNE F  +D E A K Y  A++ICP    ++ AVLY N+A A  +LE N  A+++  KA+E+ P+Y      R+K++E   K  EAL D       D
Sbjct:   87 LTANKEKADKLKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLYGNRAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKPDEALEDYKKVTEID 197

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Zebrafish
Match: tomm70a (translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) [Source:ZFIN;Acc:ZDB-GENE-030131-8173])

HSP 1 Score: 155.221 bits (391), Expect = 7.707e-40
Identity = 145/557 (26.03%), Postives = 248/557 (44.52%), Query Frame = 2

Query:  143 KWITSTLVLVATVIGVYYFYXXXXXXXXXXXXVRFIEK-----LADQTDSQINEANNILQKRR--DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINSKN--ISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            +W  + LV    V+GV   Y       +     R  E+      A     Q    N  L+     D A   K KGN++F    +++AIK Y  AI +CP +   D +  Y+N+A A  +     E + + ++A+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ KE+   +EP++ S + I  YF +F DD     L    +  E+        ++  +  Y    Q ++E      I +   EI S     ++  LLR TFYLL      A  D  RVI   ++    + NA+IKR ++ + +       + F  A +I+   AD+++HRG       Q + A+ DF + ++L  +  LA     F  Y   Y    P   +   D FE++I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L   L L+ +AIE D K   +Y  +  I ++ G L+KAI+M  KAI  A++   M     + +   AQ  V++ + +
Sbjct:   18 RWQLALLVGTPIVLGVGAVYLWNRSRAKEKQGKRNGERKTPEGSASPVQGQHGATNPELENLSPLDRAQSAKNKGNKYFKAGKYDHAIKCYTEAIGLCPKEKKGDLSTFYQNRAAAYEQQMKWTEVIQDCSQAVELNPRYVKALFRRAKALEKLDNKKECLEDVTAVCILEVFQNQQSMLLADKVLKQLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKKDEDKDKEGEASEVKGSSGYLKAKQYMEEENYDKIISECTKEIESGGRYSAEALLLRATFYLLIGNATAAQPDLDRVINMNDASVKLRANALIKRGSMYMQQQQPQLSTQDFNMAAEIDHRNADVYHHRGQLKILLDQVEEAVGDFDECIKLRPDSALAQAQKCFALYRQAYTGNNPSQVQKAMDGFEDVIRRFPKCAEGYALYAQALTDQQQFGKADEMYDKCIELEPDNATTYVHKGLLQLQWKQDLEMGLELISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIDMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVAKKYGL 574

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Query:  143 KWITSTLVLVATVIGVYYFYXXXXXXXXXXXXVRFIEK-----LADQTDSQINEANNILQKRR--DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINSKN--ISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            +W  + LV    V+GV   Y       +     R  E+      A     Q    N  L+     D A   K KGN++F    +++AIK Y  AI +CP +   D +  Y+N+A A  +     E + + ++A+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ KE+   +EP++ S + I  YF +F DD     L    +  E+        ++  +  Y    Q ++E      I +   EI S     ++  LLR TFYLL      A  D  RVI   ++    + NA+IKR ++ + +       + F  A +I+   AD+++HRG       Q + A+ DF + ++L  +  LA     F  Y   Y    P   +   D FE++I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L   L L+ +AIE D K   +Y  +  I ++ G L+KAI+M  KAI  A++   M     + +   AQ  V++ + +
Sbjct:   18 RWQLALLVGTPIVLGVGAVYLWNRSRAKEKQGKRNGERKTPEGSASPVQGQHGATNPELENLSPLDRAQSAKNKGNKYFKAGKYDHAIKCYTEAIGLCPKEKKGDLSTFYQNRAAAYEQQMKWTEVIQDCSQAVELNPRYVKALFRRAKALEKLDNKKECLEDVTAVCILEVFQNQQSMLLADKVLKQLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKKDEDKDKEGEASEVKGSSGYLKAKQYMEEENYDKIISECTKEIESGGRYSAEALLLRATFYLLIGNATAAQPDLDRVINMNDASVKLRANALIKRGSMYMQQQQPQLSTQDFNMAAEIDHRNADVYHHRGQLKILLDQVEEAVGDFDECIKLRPDSALAQAQKCFALYRQAYTGNNPSQVQKAMDGFEDVIRRFPKCAEGYALYAQALTDQQQFGKADEMYDKCIELEPDNATTYVHKGLLQLQWKQDLEMGLELISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIDMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVAKKYGL 574

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Zebrafish
Match: ttc1 (tetratricopeptide repeat domain 1 [Source:ZFIN;Acc:ZDB-GENE-041114-80])

HSP 1 Score: 49.2914 bits (116), Expect = 9.045e-6
Identity = 35/110 (31.82%), Postives = 61/110 (55.45%), Query Frame = 2

Query:  305 QKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFD 634
            + RR E+L +K KGN  F   +   A + Y  A+ +CP+ F +D ++L+ N+A +    +    A+++ +KA+E+ P Y  A   R++++E   KL EAL D    +  D
Sbjct:  136 ESRRKESLELKEKGNAQFKSGEHVEAEESYSAALKLCPVCFTKDRSILFSNRAASRLHQDKKDGAISDCSKAIELNPNYVRAILRRAELYEKTDKLDEALEDYKTVLEKD 245

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BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Zebrafish
Match: ttc1 (tetratricopeptide repeat domain 1 [Source:ZFIN;Acc:ZDB-GENE-041114-80])

HSP 1 Score: 49.2914 bits (116), Expect = 9.701e-6
Identity = 35/110 (31.82%), Postives = 61/110 (55.45%), Query Frame = 2

Query:  305 QKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFD 634
            + RR E+L +K KGN  F   +   A + Y  A+ +CP+ F +D ++L+ N+A +    +    A+++ +KA+E+ P Y  A   R++++E   KL EAL D    +  D
Sbjct:  147 ESRRKESLELKEKGNAQFKSGEHVEAEESYSAALKLCPVCFTKDRSILFSNRAASRLHQDKKDGAISDCSKAIELNPNYVRAILRRAELYEKTDKLDEALEDYKTVLEKD 256

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Xenopus
Match: tomm70 (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:100125169])

HSP 1 Score: 158.303 bits (399), Expect = 8.995e-41
Identity = 138/501 (27.54%), Postives = 234/501 (46.71%), Query Frame = 2

Query:  290 ANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            A   LQ   ++A   K KGN++F  + +E AI+ Y  AI++CP+    D +  Y+N+A A  +L+N  E + +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ K++   +EP++ S + I  YF +F DD     L    +  E+         +     Y    + ++E      I +   E+ S  K +++  LLR TFYLL      A  D  +VI         + NA+IKR ++ + +       + F  A DI+P  AD+++HRG       Q + A++DF + + L  +  LA     F  Y   Y    P   K     FE++I   P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G L+KAIEM  KAI  A++   M     + +   AQ  V+R + +
Sbjct:   62 AEGSLQAGCEKAQAAKNKGNKYFKASKYEQAIQCYTEAISLCPVDTKSDLSTFYQNRAAAHEQLQNWKEVVQDCTKAVELNPRYVKALFRRAKAHERLDNKKECLEDVTAVCILEGFQNQQSMFLADKVLKLLGKEKAKDKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKSDEDKDKEGEAAVVKEKSGYLKAKKYMEEENYDKIISECTKEVESVGKYVAEALLLRATFYLLIGNAAAAKPDLDQVISMEECNVKLRANALIKRGSMYMQQQLPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEDAVEDFDECIRLRPDSALAQAQKCFALYRKAYTGSNPLQIKEAMQGFEDVITKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLEKGLDLISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVARKYGL 562

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Xenopus
Match: tomm70 (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:100125169])

HSP 1 Score: 156.762 bits (395), Expect = 1.430e-40
Identity = 135/492 (27.44%), Postives = 231/492 (46.95%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            ++A   K KGN++F  + +E AI+ Y  AI++CP+    D +  Y+N+A A  +L+N  E + +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ K++   +EP++ S + I  YF +F DD     L    +  E+         +     Y    + ++E      I +   E+ S  K +++  LLR TFYLL      A  D  +VI         + NA+IKR ++ + +       + F  A DI+P  AD+++HRG       Q + A++DF + + L  +  LA     F  Y   Y    P   K     FE++I   P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G L+KAIEM  KAI  A++   M     + +   AQ  V+R + +
Sbjct:    7 EKAQAAKNKGNKYFKASKYEQAIQCYTEAISLCPVDTKSDLSTFYQNRAAAHEQLQNWKEVVQDCTKAVELNPRYVKALFRRAKAHERLDNKKECLEDVTAVCILEGFQNQQSMFLADKVLKLLGKEKAKDKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKSDEDKDKEGEAAVVKEKSGYLKAKKYMEEENYDKIISECTKEVESVGKYVAEALLLRATFYLLIGNAAAAKPDLDQVISMEECNVKLRANALIKRGSMYMQQQLPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEDAVEDFDECIRLRPDSALAQAQKCFALYRKAYTGSNPLQIKEAMQGFEDVITKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLEKGLDLISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVARKYGL 498

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Xenopus
Match: tomm70 (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:100125169])

HSP 1 Score: 157.147 bits (396), Expect = 2.742e-40
Identity = 136/502 (27.09%), Postives = 235/502 (46.81%), Query Frame = 2

Query:  287 EANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            +   +L+   ++A   K KGN++F  + +E AI+ Y  AI++CP+    D +  Y+N+A A  +L+N  E + +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ K++   +EP++ S + I  YF +F DD     L    +  E+         +     Y    + ++E      I +   E+ S  K +++  LLR TFYLL      A  D  +VI         + NA+IKR ++ + +       + F  A DI+P  AD+++HRG       Q + A++DF + + L  +  LA     F  Y   Y    P   K     FE++I   P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G L+KAIEM  KAI  A++   M     + +   AQ  V+R + +
Sbjct:   72 DGGELLESPLEKAQAAKNKGNKYFKASKYEQAIQCYTEAISLCPVDTKSDLSTFYQNRAAAHEQLQNWKEVVQDCTKAVELNPRYVKALFRRAKAHERLDNKKECLEDVTAVCILEGFQNQQSMFLADKVLKLLGKEKAKDKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKSDEDKDKEGEAAVVKEKSGYLKAKKYMEEENYDKIISECTKEVESVGKYVAEALLLRATFYLLIGNAAAAKPDLDQVISMEECNVKLRANALIKRGSMYMQQQLPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEDAVEDFDECIRLRPDSALAQAQKCFALYRKAYTGSNPLQIKEAMQGFEDVITKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLEKGLDLISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVARKYGL 573

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Xenopus
Match: tomm70 (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:100125169])

HSP 1 Score: 155.992 bits (393), Expect = 6.903e-40
Identity = 135/492 (27.44%), Postives = 231/492 (46.95%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            ++A   K KGN++F  + +E AI+ Y  AI++CP+    D +  Y+N+A A  +L+N  E + +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ K++   +EP++ S + I  YF +F DD     L    +  E+         +     Y    + ++E      I +   E+ S  K +++  LLR TFYLL      A  D  +VI         + NA+IKR ++ + +       + F  A DI+P  AD+++HRG       Q + A++DF + + L  +  LA     F  Y   Y    P   K     FE++I   P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G L+KAIEM  KAI  A++   M     + +   AQ  V+R + +
Sbjct:   73 EKAQAAKNKGNKYFKASKYEQAIQCYTEAISLCPVDTKSDLSTFYQNRAAAHEQLQNWKEVVQDCTKAVELNPRYVKALFRRAKAHERLDNKKECLEDVTAVCILEGFQNQQSMFLADKVLKLLGKEKAKDKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKSDEDKDKEGEAAVVKEKSGYLKAKKYMEEENYDKIISECTKEVESVGKYVAEALLLRATFYLLIGNAAAAKPDLDQVISMEECNVKLRANALIKRGSMYMQQQLPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEDAVEDFDECIRLRPDSALAQAQKCFALYRKAYTGSNPLQIKEAMQGFEDVITKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLEKGLDLISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVARKYGL 564

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Xenopus
Match: tomm70 (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:100125169])

HSP 1 Score: 155.992 bits (393), Expect = 7.269e-40
Identity = 136/503 (27.04%), Postives = 235/503 (46.72%), Query Frame = 2

Query:  284 NEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            N  +++     ++A   K KGN++F  + +E AI+ Y  AI++CP+    D +  Y+N+A A  +L+N  E + +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ K++   +EP++ S + I  YF +F DD     L    +  E+         +     Y    + ++E      I +   E+ S  K +++  LLR TFYLL      A  D  +VI         + NA+IKR ++ + +       + F  A DI+P  AD+++HRG       Q + A++DF + + L  +  LA     F  Y   Y    P   K     FE++I   P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G L+KAIEM  KAI  A++   M     + +   AQ  V+R + +
Sbjct:   71 NPGSHLSTSPLEKAQAAKNKGNKYFKASKYEQAIQCYTEAISLCPVDTKSDLSTFYQNRAAAHEQLQNWKEVVQDCTKAVELNPRYVKALFRRAKAHERLDNKKECLEDVTAVCILEGFQNQQSMFLADKVLKLLGKEKAKDKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKSDEDKDKEGEAAVVKEKSGYLKAKKYMEEENYDKIISECTKEVESVGKYVAEALLLRATFYLLIGNAAAAKPDLDQVISMEECNVKLRANALIKRGSMYMQQQLPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEDAVEDFDECIRLRPDSALAQAQKCFALYRKAYTGSNPLQIKEAMQGFEDVITKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLEKGLDLISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVARKYGL 573

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Mouse
Match: Tomm70a (translocase of outer mitochondrial membrane 70A [Source:MGI Symbol;Acc:MGI:106295])

HSP 1 Score: 148.673 bits (374), Expect = 2.284e-37
Identity = 131/492 (26.63%), Postives = 228/492 (46.34%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKS----CFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            D A   K KGN++F    +E AI+ Y  AI++CP +   D +  Y+N+A A  +L+   E   +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E  KE+   +EP++ S + I  YF +F DD     +    +  E+       +++     Y    Q ++E      I +   EI++  K +++  LLR TFYLL      A  D  +VI    +    + NA+IKR T+ + +   +   + F  A +I+P  +D+++HRG         + A+ DF   + L  +  LA     F  Y   Y  +  S        FE +I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G +EKAI+M  KAI  A++   M     + +   AQ  V++ + +
Sbjct:  115 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEIIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGL 606

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. UniProt/SwissProt
Match: sp|O94826|TOM70_HUMAN (Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1)

HSP 1 Score: 158.303 bits (399), Expect = 7.976e-40
Identity = 135/492 (27.44%), Postives = 230/492 (46.75%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKS----CFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            D A   K KGN++F    +E AI+ Y  AI++CP +   D +  Y+N+A A  +L+   E   +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E+ KE+   +EP++ S + I  YF +F DD     +    +  E+       +++     Y    Q ++E      I +   EI++  K +++  LLR TFYLL      A  D  +VI    +    + NA+IKR ++ + +   L   + F  A DI+P  AD+++HRG       Q + A+ DF + + L  E  LA     F  Y   Y  +  S        FE +I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L   L L+ +AIE D K   +Y  +  I ++ G +EKAI+M  KAI  A++   M     + +   AQ  V++ + +
Sbjct:  112 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGL 603

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. UniProt/SwissProt
Match: sp|Q75Q39|TOM70_RAT (Mitochondrial import receptor subunit TOM70 OS=Rattus norvegicus OX=10116 GN=Tomm70 PE=1 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 1.524e-36
Identity = 131/492 (26.63%), Postives = 228/492 (46.34%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKS----CFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            D A   K KGN++F    +E AI+ Y  AI++CP +   D +  Y+N+A A  +L+   E   +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E  KE+   +EP++ S + I  YF +F DD     +    +  E+       +++     Y    Q ++E      I +   EI++  K +++  LLR TFYLL      A  D  +VI    +    + NA+IKR T+ + +   +   + F  A +I+P  +D+++HRG         + A+ DF   + L  +  LA     F  Y   Y  +  S        FE +I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G +EKAI+M  KAI  A++   M     + +   AQ  V++ + +
Sbjct:  114 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGL 605

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. UniProt/SwissProt
Match: sp|Q9CZW5|TOM70_MOUSE (Mitochondrial import receptor subunit TOM70 OS=Mus musculus OX=10090 GN=Tomm70 PE=1 SV=2)

HSP 1 Score: 148.673 bits (374), Expect = 1.597e-36
Identity = 131/492 (26.63%), Postives = 228/492 (46.34%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINS--KNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKS----CFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            D A   K KGN++F    +E AI+ Y  AI++CP +   D +  Y+N+A A  +L+   E   +  KA+E+ P+Y  A   R+K  E L   +E L D+TA    +      S+   D ++K +  E  KE+   +EP++ S + I  YF +F DD     +    +  E+       +++     Y    Q ++E      I +   EI++  K +++  LLR TFYLL      A  D  +VI    +    + NA+IKR T+ + +   +   + F  A +I+P  +D+++HRG         + A+ DF   + L  +  LA     F  Y   Y  +  S        FE +I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L + L L+ +AIE D K   +Y  +  I ++ G +EKAI+M  KAI  A++   M     + +   AQ  V++ + +
Sbjct:  115 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEIIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGL 606

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BLAST of Mitochondrial import receptor subunit TOM70 vs. UniProt/SwissProt
Match: sp|P23231|TOM70_NEUCR (Mitochondrial import receptor subunit tom70 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=tom70 PE=2 SV=3)

HSP 1 Score: 106.301 bits (264), Expect = 1.480e-22
Identity = 120/496 (24.19%), Postives = 219/496 (44.15%), Query Frame = 2

Query:  308 KRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEI-LKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQ------SLSRCIKLFIAG--QYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIE-NPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSG----SVMNFIADIKFLF---NKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTF 1744
            +R+  A  +K  GN+ +   DF  AI  Y  AI IC     +   V Y N+A   N L    + + +   AL++ P Y  A + R+  ++ L +  +AL D TA+   D      S   ++ ++K  A  + KE +  K P L S   +  Y ++F   P P  L   ++ SE          L         G  + SA F++  ++ +        + +  + LRGTF+ L  + E AL D S+ IE +P         + IKRA++ L   +    EE F +A++ N    D++YHR   H   G++  A  D+QK+++L+S+ + + +     +Y +       S    F   ++    + +V   Y ++L+       A    D  + +++++     +V+  I     LF       EA  L E+A+  DP+   +   +A +L++ G++ +A++  E+A + AR    +   +   E    Q+ V   +
Sbjct:  131 ERKAYAAKLKELGNKAYGSKDFNKAIDLYSKAI-IC-----KPDPVYYSNRAACHNALAQWEQVVADTTAALKLDPHYVKALNRRANAYDQLSRYSDALLDFTASCIIDGFRNEQSAQAVERLLKKFAENKAKEILETKPPKLPSSTFVGNYLQSFRSKPRPEGLEDSVELSEETGLGQLQLGLKHLESKTGTGYEEGSAAFKKALDLGEL-----GPHEALAYNLRGTFHCLMGKHEEALADLSKSIELDPA-----MTQSYIKRASMNLELGHPDKAEEDFNKAIEQNAEDPDIYYHRAQLHFIKGEFAEAAKDYQKSIDLDSDFIFSHIQLGVTQYKMG---SIASSMATFRRCMKNFDQTPDVYNYYGELLLDQNKFQEAIEKFDTAIALEKETKPMCMNVLPLINKALALFQWKQDYAEAEQLCEKALIIDPECDIAVATMAQLLLQQGKVVEALKFFERAAELARTEGELVNALSYAEATRTQIQVQENY 607

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BLAST of Mitochondrial import receptor subunit TOM70 vs. UniProt/SwissProt
Match: sp|O14217|TOM70_SCHPO (Probable mitochondrial import receptor subunit tom70 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=tom70 PE=1 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 1.352e-21
Identity = 119/494 (24.09%), Postives = 222/494 (44.94%), Query Frame = 2

Query:  305 QKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINIC--PLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEILKE--PVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNI-SQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEK-VNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHG-KSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLA-ENIVDKLLLIDRDSGSVMNFIADIK-----FLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTF 1744
            ++R   A  +K  GN+ +   ++ NAI  Y  AI     P+ F  + A  Y         +++ +EAL+       +   Y  A + RS  +E LGKL EAL D T +  FD          ++ ++K +A E+    +LKE  P L +   I  Y  +F   P P   N      + + +L+   +    G+Y   + + +E    +   +S ++ ++ H L GTF  +S   + ++++F+  I     K   K +   I+ +   L EN++  + +V  +A  ++   +DL+YHR      SG++  AI D+QK++ L+   + + +     +    Y  H        FE+  +  PNSSEV   + ++L+     D A +N    + L  R+  ++M+ +  I      F + K + +A  L  +A+  DP+   +   +A  L++ G+  +A+E  EK+ + AR    M       E    Q+ ++  +
Sbjct:  145 EERAKLAAELKTLGNKAYGQKEYANAIDYYTQAITCSHDPI-FFSNRAACYAAIGDFEQVIKDTSEALS-------LDSSYVKALNRRSAAYEQLGKLDEALMDSTVSCIFDGFANESMTATVERLLKKVA-EKKSSALLKERPPKLPAASFIQTYLDSFHAQPKPLFDN----KFDGDAALAEAYEYLEKGEYQLSYDKAKE--SCLGSFSSPSVNARTHNLVGTFKFVSGDSKGSMENFNAAI-----KLDRKFIQPYIRLSAAYLDENDNEKMWKVLNDAESVDKTDSDLYYHRAQVRFVSGEFAEAISDYQKSIALDDSFIYSHIQLGVAQ----YKTHAIAESMKTFEDCKKRFPNSSEVYNYFGEILLDQQKFDDAVKNFDHAIELEKREHLTIMSAMPLINKALAVFQWKKDISQAENLCRQALSADPECDIAIASMAQFLLQQGKAREALEYFEKSAQLARTESEMVNAFSYAEATRTQIALTEKY 614

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BLAST of Mitochondrial import receptor subunit TOM70 vs. TrEMBL
Match: A0A1J1HIM9 (CLUMA_CG000014, isoform A OS=Clunio marinus OX=568069 GN=CLUMA_CG000014 PE=4 SV=1)

HSP 1 Score: 196.823 bits (499), Expect = 4.644e-51
Identity = 164/584 (28.08%), Postives = 301/584 (51.54%), Query Frame = 2

Query:  134 PSIKWITSTLVLVATVIGVYYFYXXXXXXXXXXXXVRFIEKLADQ------------TDSQINEANNILQ---------KRRD-----EALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATI-LLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEY-WLTYPQHGKSCF---DQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGS--VMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQ 1783
            P  +W  + L+     IG+ YFY  K +     + V  +++ AD+             D+ ++ AN + +         K++D     +A+  K  GNE F    ++ AIK Y  AI++CP     D +  Y+N+A A  +L+       +  KALE+ P+Y  A   R + +E L +L+  L D+TA    +    ++S+   D I+K++ ++  KE +L KEPV  S+  +  YFK+F  DP    ++  +  S   +   R IK F    Y+       E ++T ++ +   +  + LLRGTFYLLS + EL+LKD + +I+N  +    + NA+ KRA++ + T+  +L+ E+ F++A++I+P   D+++HRG  +    + + A+ DF KA +L  ++ L  VH +++EY      Q     F   ++F   I+  P+  EV  ++ ++L      +L+++  +K + I+  +    V   + ++++  N + EAL +LE+AIE D K   +Y  L  + ++ G LE+AI + EKA+K A++   +     +K+   AQLNV++   + +  ++  + Q
Sbjct:    7 PFPRWQLAILLGTPLAIGLGYFYWRKQQTAIEES-VDDVDEKADKKLKKGVKSISIDGDTTLSAANGVKKSAALKDEPAKKKDLSPFEQAVKHKESGNECFKNGKYDEAIKFYNQAIDVCPKDKDIDLSQFYQNRAAAYEQLKKWTSVEQDCTKALELNPRYIKALHRRCRAYENLKQLELCLEDVTAVAILEGFQNNNSLIFADRILKDLGMKHAKEAMLTKEPVEPSKHFVVNYFKSFSQDP----VHKVVVTSSEPKGFVRAIKAFKDANYNEVINACTEEIETCEDDSEYKLEAI-LLRGTFYLLSGQYELSLKDLNTIIKNKEADAKLRSNALTKRASLHMQTDEKNLSFED-FEKAIEIDPENPDIYHHRGQVYLLVEELQNAVADFSKATKLAPKNPLTYVHKLYSEYRQAVNDQDNTKLFAKVEEFSEAIKQFPSCIEVYSLFAQILSDQQQFELSDDYFEKAMKIEPGNAGLYVHRGLLNLQWKGN-MNEALKMLEKAIEVDDKCEFAYETLGTVEVQRGNLERAISLFEKAMKLAKSEMELIHIFSLKDAAQAQLNVTKKMGLSLASLMSSMPQ 582

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BLAST of Mitochondrial import receptor subunit TOM70 vs. TrEMBL
Match: A0A0N1PKE8 (Mitochondrial import receptor subunit TOM70 OS=Papilio machaon OX=76193 GN=RR48_01610 PE=4 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 1.364e-46
Identity = 156/547 (28.52%), Postives = 257/547 (46.98%), Query Frame = 2

Query:  134 PSIKWITSTLVLVATVIGVYYFYXXXXXXXXXXXXVRFIEKLADQTDSQINEANNI--LQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEILK-EPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQ----FENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            P  KW  + L+     IG+ Y Y      +     V  ++  A  T S  NE NN    +   D A+ +K  GN  F+  +F+ AI  Y  AI  CP     D A  Y+N++    + E   +   +   AL++  +Y  AF  RS+  E  G L  AL D+T+A   +      S+   D I+K +  +  +E + K +PV+ S+  I  YF AF ++P      + ++D+      ++  K   A  Y +      E L    E + K   +  LLR TFYLL  R + A  D ++VI++ N+ P  KVNA+IKRA++     N+ +  E F  A  ++P+ +D+++HRG  +    +   A  +F KA+ELN    +A +   + +Y L          +Q    FE  ++  P  +E   +Y +VL        AE++ D  L +D D+ ++      ++   N    +A+ L+ +AIE D K   +Y  L  I ++ G L +++E+ EKAI  A+    M     +K+  AAQL VS  + +
Sbjct:    8 PFPKWQLAILLGAPLAIGLGYLYLRNRLEDPEKKKVADLK--AKTTISLDNEENNAKAAESAIDRAMKLKGAGNRAFHAGEFDKAIALYNEAIEACPPDHTVDLATFYQNRSACYEKREMWEQVKEDCTFALKLNEKYVKAFLRRSRAAEKSGDLVLALEDVTSACILEKFQVQSSLVNADRILKALGRQHAREALAKRQPVMPSKHFIKTYFSAFSEEPIT---KLQLEDNATG-GFAKAKKALEAQDYESVVDACTEEL----EADGKYKYEALLLRATFYLLLGRHDEAQADLAKVIDS-NASPKVKVNALIKRASLFTQLENTEHCLEDFAHAAKLDPSNSDIYHHRGQVYLLLERMDEATAEFAKAVELNPNFSIAYIQKCYADYRLAQLHKNVGALNQVRSEFERALEKFPRCAEAYILYAQVLSDQQEWGRAESLFDSALSVDPDNAALYVHKGLVQLQKNTDFDKAVKLINKAIEMDEKCDFAYETLGTIEVQRGNLRRSLELFEKAIALAKTELEMTHLFSLKDAAAAQLKVSERWGL 543

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BLAST of Mitochondrial import receptor subunit TOM70 vs. TrEMBL
Match: A0A194PI34 (Mitochondrial import receptor subunit TOM70 OS=Papilio xuthus OX=66420 GN=RR46_13934 PE=4 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 5.735e-45
Identity = 155/547 (28.34%), Postives = 255/547 (46.62%), Query Frame = 2

Query:  134 PSIKWITSTLVLVATVIGVYYFYXXXXXXXXXXXXVRFIEKLADQTDSQINEANN--ILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEILK-EPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQ----FENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            P  KW  + L+     IG+ Y Y      +     V  ++  A  T S  NE NN  + +   D A+ +K  GN  F+  +F+ AI  Y  AI  CP     D A  Y+N++    + E   +   +   AL++  +Y  AF  RS+  E  G L  AL D+T+A   +      S+   D I+K +  +  +E + K +PV+ S+  I  YF AF ++P      + ++D+      ++  K   A  Y +      E L    E + K   +  LLR TFYLL  R + A  D ++VI++ N+    KVNA+IKRA++     N+    E F  A  ++P+ +D+++HRG  +    +   A  +F KA+ELN    +A +   + +Y L           Q    FE  ++  P  +E   +Y +VL        AE++ D  L +D D+ ++      ++   N    +A+ L+ +AIE D K   +Y  L  I ++ G L +++E+ EKAI  A+    M     +K+  AAQL VS  + +
Sbjct:    8 PFPKWQLAILLGAPLAIGLGYLYLRNRLEDPEKKKVADLK--AKTTISLDNEENNAKVAESAIDRAMKLKGAGNRAFHAGEFDKAIALYNEAIEACPPDHTVDLATFYQNRSACYEKREMWEQVKEDCTFALKLNEKYVKAFLRRSRAAEKSGDLVLALEDVTSACILERFQVQSSLVNADRILKALGRQHAREALAKRQPVMPSKHFIKTYFSAFSEEPIT---KLQLEDNATG-GFAKAKKALDAQDYESIVDACTEEL----EADGKYKYEALLLRATFYLLLGRHDEAQADLAKVIDS-NASLKVKVNALIKRASLFTQLENTERCLEDFAHAAKLDPSNSDIYHHRGQVYLLLERMDEATAEFAKAVELNPNFSIAYIQKCYADYRLAQLHKNVGALTQVRSDFERALEKFPRCAEAYILYAQVLSDQQEWGRAESLFDSALSVDPDNAALYVHKGLVQLQKNTDFDKAVKLINKAIEMDEKCDFAYETLGTIEVQRGNLRRSLELFEKAIALAKTELEMTHLFSLKDAAAAQLKVSERWGL 543

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BLAST of Mitochondrial import receptor subunit TOM70 vs. TrEMBL
Match: A0A232FEY5 (Uncharacterized protein OS=Trichomalopsis sarcophagae OX=543379 GN=TSAR_007507 PE=4 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 1.304e-44
Identity = 153/563 (27.18%), Postives = 272/563 (48.31%), Query Frame = 2

Query:  143 KWITSTLVLVATVIGVYYFYXXXXXXXXXXXXVRFIEKLADQT--------DSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEI-LKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTI--DEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHG----KSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLF-NKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQ 1783
            KW  + +V     +G+ Y Y     N       R   K + +         D    E     +   ++A   K +GN+FF+   F+ AI QY +AI  CP++ + + A  Y+N+A A  +L+  +    +  KALE+ P+Y  A   R++  E+  +L+ AL DITAA   +      ++   D ++K +  +  +E +  K+P++ S+  I  YF AF +DP  + L+  ++  E+N   ++ +      +Y        E L+ +  DE +S +  ++ +LRGTFYLL  + E AL+D S VI +  S    KVNA+IKRA++ +   ++      F++A  I+PNC D++++RG  H    +   A  DF+KA+ELN    +A V   F +Y     +       +    F    +  P+ SE   +Y ++L+ S     A++   K    D  + +++ +   ++  + N + +A+  + +AIE D K   +Y  L  I ++ G L+ AI + +KA+   R    +     +++   AQL VS   D    D+IR + +
Sbjct:   13 KWQLALVVGAPVALGLGYMYYKNCANKPEEKPGRGKPKKSSRENGEKQISIDGDFPENVTAAETPLEKAQKYKGEGNKFFSAGKFDEAIAQYNLAIETCPVENVEELATFYQNRAAAYEKLKKFSAVRADCTKALELKPRYVKALIRRARAMESNNELETALEDITAACILEKFSSQSTLYTADKVLKQLGKQHAQEYMATKKPIMPSKHFIGTYFLAFYNDPILAKLD-GLETVEDNTPFNKALTALKKQEYDDVIPLCTEELKNLATDE-DSLHKMEVLVLRGTFYLLLGQHENALEDLSAVIGSDASSKELKVNALIKRASMFIQLESAEKSFNDFEDAEKIDPNCGDVYHNRGQVHLLMERVDEAKADFEKAVELNPGFGVAYVQKCFADYRFAVSKRDMNLMNTSMTNFNKAFEKFPDCSECYTLYAQMLVDSQDFARADSYFLKAAKRDPKNATILVYRGLLQLQWQNNIEKAVEYIRKAIELDDKCEFAYETLGTIEVQRGNLKDAISLFDKALALGRTSMELTHIFSLRDAAQAQLTVS---DRLGSDIIRSLQE 570

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. TrEMBL
Match: A0A553PL71 (Uncharacterized protein OS=Tigriopus californicus OX=6832 GN=TCAL_12222 PE=4 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 1.675e-43
Identity = 156/583 (26.76%), Postives = 274/583 (47.00%), Query Frame = 2

Query:  128 KLPSIKWITSTLVLVATVIGVYYFY------XXXXXXXXXXXXVRFIEKLADQTDSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIF------------ETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL---KEPVLISEKEITKYFKAFIDDP----FPSSLNIDIQDSENNQ-----SLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTE-NNSLNIEEV----FKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKS----CFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLF-NKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPI 1756
            +LP+  W   T+  VA   G+ Y++       + ++     +  R  +  AD  +    E   + Q   + A+ +K KGN++F    +E AIK Y  AI++CP     D +  Y+N+A A +                    QY  A D R+K+             E++ KL+ AL D+TA    D   K + +  +D I+K +   RV+ +I    ++P   S   I +YF++F +DP       +   D  DS  ++        R +K      Y    Q +    + ID+ +  ++++  LLRGTF++LS +   A +DF++VIE+  +  S +VNA+IKRA++ + +  + +   E+    FK+  D++   AD+++HRG  H    Q   A++DF KA+ELN    +A V  ++ EY +      KS       QF++ ++  P   E   ++ +VL      D AE++  +   +D  + +++     I       +  A++L+++A+E D K    Y  L  I ++ G+L++AIE+ +KAI  A     M     +K    AQ  VS+ F I +
Sbjct:   20 RLPTWFWPVLTVSGVAVTAGLLYWWLNPSPSPSPSQTKSQRSAARPEKPGADGAEDPEEE---LPQDPFERAVSLKNKGNKYFKGGRYELAIKCYNEAIDVCPTHKEHDLSTFYQNRAAAYD--------------------QYLKAMDRRAKVLRKQVRKLQSADGESVNKLRMALEDMTAVCILDGFQKQEYLMLVDTILKELG--RVEAKIAIRDRQPGFTSHHFIQQYFQSFAEDPIVKLLAKNTESDSDDSPEDRDNATGGFMRALKDLKDEMYE---QVIDHCTEEIDQ-SGAHVNEAKLLRGTFFILSKQPNEAFQDFNQVIEDSEADVSLRVNALIKRASLYIQQCKDPMKDPELSFADFKQGQDLDETNADIYHHRGQVHLLIDQTPKALEDFNKAVELNPGFPIAYVQKLYTEYRIASTSDNKSEIPKLIQQFQDAMEKFPKCVETYALFAQVLSDQSQFDRAEDVYQQAQKVDPKNANILVHRGLIALQAKGDIEGAVSLIKKALEVDDKCEFGYETLGTIEVQRGKLKEAIELFDKAIPIANTELEMAHLFGLKHAANAQTTVSKRFGISL 573

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Cavefish
Match: tomm70a (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:103032171])

HSP 1 Score: 157.918 bits (398), Expect = 1.646e-40
Identity = 131/492 (26.63%), Postives = 231/492 (46.95%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINSKN--ISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            D A   K KGN++F    +E AI+ Y  AIN+CP +   D +  Y+N+A A  +     E + + ++A+E+ P+Y  A   R+K  E L   +E L D+TA    ++     S+   D ++K +  E+ K++   +EP++ S + I  YF +F DD     L    +  E+        ++  +  Y    Q ++E      I +   E+ S+    ++  LLR TFYLL      A  D  +VI   ++    + NA+IKR ++ + +       + F  A +I+   AD+++HRG       Q + A+ DF + + L  +  LA     F  Y   Y    P   ++  D FE++I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L   L L+ +AIE D K   +Y  +  I ++ G L+KAI+M  KAI  A++   M     + +   AQ  V+R + +
Sbjct:  133 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAINMCPREQKSDLSTFYQNRAAAYEQQAKWTEVVQDCSQAVEMNPRYVKALFRRAKALERLDNKKECLEDVTAVCILEAFQNQQSMLLADKVLKQLGKEKAKDKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKKDEDKDKEGEAAEVTGSSGYLKAKQYMEEENYDKIISECTKEVESRGRYTAEALLLRATFYLLIGNATAAQPDLDKVINMQDANVKLRANALIKRGSMYMQQQQPHLSTQDFNMAAEIDSRNADVYHHRGQLKILLDQVEEAVADFDECILLRPDSALAQAQKCFALYRQAYTGNNPSQVQTAMDGFEDVIRRFPRCAEGYALYAQALTDQQQFGKADEMYDKCIELEPDNATTYVHKGLLQLQWKQDLDMGLDLISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIDMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVARKYGL 624

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Cavefish
Match: tomm70a (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:103032171])

HSP 1 Score: 133.265 bits (334), Expect = 2.164e-32
Identity = 116/446 (26.01%), Postives = 207/446 (46.41%), Query Frame = 2

Query:  317 DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINSKN--ISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIK 1612
            D A   K KGN++F    +E AI+ Y  AIN+CP +   D +  Y+N+A A  +     E + + ++A+E+ P+Y  A   R+K  E L   +E L D+TA    ++     S+   D ++K +  E+ K++   +EP++ S + I  YF +F DD     L    +  E+        ++  +  Y    Q ++E      I +   E+ S+    ++  LLR TFYLL      A  D  +VI   ++    + NA+IKR ++ + +       + F  A +I+   AD+++HRG       Q + A+ DF + + L  +  LA     F  Y   Y    P   ++  D FE++I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L   L L+ +AIE D K   +Y  +  I ++
Sbjct:  133 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAINMCPREQKSDLSTFYQNRAAAYEQQAKWTEVVQDCSQAVEMNPRYVKALFRRAKALERLDNKKECLEDVTAVCILEAFQNQQSMLLADKVLKQLGKEKAKDKYKNREPLMPSPQFIKSYFSSFTDDIISQPLQKGEKKDEDKDKEGEAAEVTGSSGYLKAKQYMEEENYDKIISECTKEVESRGRYTAEALLLRATFYLLIGNATAAQPDLDKVINMQDANVKLRANALIKRGSMYMQQQQPHLSTQDFNMAAEIDSRNADVYHHRGQLKILLDQVEEAVADFDECILLRPDSALAQAQKCFALYRQAYTGNNPSQVQTAMDGFEDVIRRFPRCAEGYALYAQALTDQQQFGKADEMYDKCIELEPDNATTYVHKGLLQLQWKQDLDMGLDLISKAIEIDNKCDFAYETMGTIEVQ 578

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Sea Lamprey
Match: ttc1 (tetratricopeptide repeat domain 1 [Source:ZFIN;Acc:ZDB-GENE-041114-80])

HSP 1 Score: 59.3066 bits (142), Expect = 3.474e-10
Identity = 53/189 (28.04%), Postives = 100/189 (52.91%), Query Frame = 2

Query:  305 QKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKS--DSVDRMDNIVKNIAIERVKEEILKE----------PVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQS 835
            ++RRDEA+++K  GN+ F   +++ A   Y  A+ +C   +    AVLY N+A+A  ++ N  +A+ +  KA+ + P Y  A   R++++E   KL EAL D  A +  + T  +  ++  R+   + ++  E++KEE+L +          P  +S    T+ F+ F  DP   S +++   ++N+ S
Sbjct:   53 ERRRDEAMMLKESGNQLFKQAEYQQAADTYTRALKVCLRAYSSHRAVLYSNRAVAHQKMGNTEKAIQDCTKAVGLDPGYARARGRRAELYEASDKLDEALEDYRALLVLEPTHSAAREACARLPEQI-HVRNEKMKEEMLGKLKDLGNLLLRPFGLS----TQNFQ-FQQDPDTGSYSVNFNQNKNSNS 235

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Yeast
Match: TOM70 (Component of the TOM (translocase of outer membrane) complex; involved in the recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins; TOM70 has a paralog, TOM71, that arose from the whole genome duplication [Source:SGD;Acc:S000005065])

HSP 1 Score: 72.4034 bits (176), Expect = 9.530e-14
Identity = 127/540 (23.52%), Postives = 214/540 (39.63%), Query Frame = 2

Query:  284 NEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITA-AVTFDSTDKS---------------------DSVDRMDNIVKNIAIERVKEEILKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAG--QYSACFQQVQEILQTIDEINSKN-----------ISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENLI----QTHPNSSEVQQMYIKVLMHSGHCDLA----------EN-----------IVDKLLLIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQ 1723
            N+AN   +++   AL +K KGN+FF    +++AIK Y  A+ +      ++  V Y N +     + +  + +    KALE+ P Y      R+   E LGK  +A+FD++  ++  D  D S                       +D        ++ +  KE   K+  L S   +  +F  F   P  +  N D  +  + + ++    L+      Y    +   +  +  +E   KN           IS  H   G F  L      A +D  + IE        +VN+ I  A I+   N+S      F +AL ++ N + ++YHRG  +     Y  A  DF KA EL+ E       N+F    L    + ++ FD  E L     +  P + EV   + ++L      D A          EN           +V K  L+ R+  +V NFI           EA  LLE+A + DP+   +   LA + ++  ++++AI + E++   AR  +   + I   E    Q
Sbjct:   86 NKANFTAEEKDKYALALKDKGNQFFRNKKYDDAIKYYNWALEL------KEDPVFYSNLSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDLSVLSLNGDFNDASIEPMLERNLNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKDKQENLPSVTSMASFFGIF--KPELTFANYDESNEADKELMNGLSNLYKRSPESYDKADESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHT--GIFKFLKNDPLGAHEDIKKAIE-----LFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPE-------NIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNP-TVENFI-----------EATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFEESADLARTMEEKLQAITFAEAAKVQ 591

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Yeast
Match: TOM71 (Mitochondrial outer membrane protein; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins; TOM71 has a paralog, TOM70, that arose from the whole genome duplication [Source:SGD;Acc:S000001159])

HSP 1 Score: 72.0182 bits (175), Expect = 1.284e-13
Identity = 123/498 (24.70%), Postives = 203/498 (40.76%), Query Frame = 2

Query:  308 KRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAV---TFDSTDKSDSVDRMDN--IVKNIAIERVKEEILKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSAC---FQQVQEIL-------------QTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVI-ENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENLIQTH-PNSSEVQQMYIKVLMHSGHCDLA---------------------ENIVDKLLLIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYAR 1669
            +R+  A+ +K +GN FF   +F  AIK Y+ AI + P     +  V Y N +       +  + +    KALEI P +  A   R+   E+LG   +A+FD++       FD       ++R  N   +K +     K+E     VL S   +  +F  F      SS+N     S N  +    +   +   YSA    +    ++L              T+D+   +N +      G F+ L       L D   ++ E+ N  P+   N+ I  A  L  + NS    + F++A+D+NP     +YHRG  +     YK A +DFQKA  LN E+    V+       L Y Q   +  + F N  +   P   EV   + ++L   G  D A                       ++ K  ++ R S      + + KF       A+ LL +A E DP+   +   LA + ++  ++++AIE+ E +   AR
Sbjct:  122 QRQAYAVQLKNRGNHFFTAKNFNEAIKYYQYAIELDP-----NEPVFYSNISACYISTGDLEKVIEFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDLSVLSLNGDFDGASIEPMLERNLNKQAMKVLNENLSKDEGRGSQVLPSNTSLASFFGIFDSHLEVSSVNT----SSNYDTAYALLSDALQRLYSATDEGYLVANDLLTKSTDMYHSLLSANTVDDPLRENAALALCYTGIFHFLKNN----LLDAQVLLQESINLHPTP--NSYIFLALTLADKENSQEFFKFFQKAVDLNPEYPPTYYHRGQMYFILQDYKNAKEDFQKAQSLNPEN----VYPYIQLACLLYKQGKFTESEAFFNETKLKFPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKRLEEVQEKIHVGIGPLIGKATILARQSSQDPTQLDEEKF-----NAAIKLLTKACELDPRSEQAKIGLAQLKLQMEKIDEAIELFEDSAILAR 595

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Nematostella
Match: EDO45236 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTM1])

HSP 1 Score: 140.969 bits (354), Expect = 1.923e-35
Identity = 128/505 (25.35%), Postives = 244/505 (48.32%), Query Frame = 2

Query:  272 DSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTID-EIN---SKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEK--VNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQH----GKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            D   +EA        ++A + K+KGN++F    +E AIK Y  AI +CP +  +D +  Y+N+A A  ++      + E  KALE+  +Y  A   R++  E L + QE L D+TA    +       +   D ++K+I  ++ KE    ++P + S   I  Y ++F  D   S  ++  QD   N S       F+A       ++  +++   D EIN   S   ++   LRGT + L  + + A+ D ++VI+  + K S K  +N +IKR ++ + E      ++ FK+A+ ++PN +D+++HR   H  + +   A +DF+K+++LN + + A +   +  Y     Q      +   + FE +   +P++ +   ++ +VL   G  + A    D  + +  ++     +   +   + +   +++ L+  AI  D K   +Y  LA + ++ G LEK++E+ +KAI   R    M +   ++E   AQ +V++   I
Sbjct:   62 DDGASEAKTTNMTPSEQAQVAKLKGNKYFKGCKYEQAIKCYTEAIELCPPENKQDLSTFYQNRAAAYEQMNQFENVVEEATKALELNSKYTKALMRRARALEKLERKQECLQDLTAVCILEGFSNPSWMMHADRVLKDIGRQKAKEHFKNRKPTIPSPTYIKAYLESFSQDEIFSD-DLQGQDDVPNDSP------FLAALEEIKEKRFDKVIDLCDDEINRGPSPCYARAMALRGTMHTLMSQVKEAIDDLTQVIDMDDDKASTKLKINCLIKRGSLHIQETREAEADQDFKKAILLDPNNSDIYHHRAQIHFLTEKIAEAKEDFEKSIKLNPDFIPARIQLAYCIYKTAVFQQNAVLARGALELFEEISTNNPDNPDALSLHAQVLQEQGQFEEACEKFDTAIKLQPENPVHKVYKGLLMVQWKQDFGKSVELVNEAISIDSKCDFAYETLATLEVQRGNLEKSVELFDKAIDLVRTEGEMAQTFSLREAAIAQHHVTKKMGI 559

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Nematostella
Match: EDO28351 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6Q4])

HSP 1 Score: 53.5286 bits (127), Expect = 1.142e-8
Identity = 34/133 (25.56%), Postives = 63/133 (47.37%), Query Frame = 2

Query:  956 LRGTFYLLSCREELALKDFSRVIENPNSKPSEK--VNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENL 1348
            LRGT + L  + + A+ D ++VI+  + K S K  +N +IKR ++ + E   +  ++ FK+A+ ++PN +D+++HR                        S H++     V      TY  H + C+   +NL
Sbjct:    3 LRGTMHTLMSQVKEAIDDLTQVIDMDDDKASTKLKINCLIKRGSLHIQETREVEADQDFKKAILLDPNNSDIYHHRA----------------------QSYHIMV----VMCTTTYTYHGHNRKCYKSKDNL 109

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Medaka
Match: tomm70a (translocase of outer mitochondrial membrane 70 [Source:NCBI gene;Acc:101169351])

HSP 1 Score: 167.548 bits (423), Expect = 4.433e-44
Identity = 147/556 (26.44%), Postives = 254/556 (45.68%), Query Frame = 2

Query:  143 KWITSTLVLVATVIGV--YYFYXXXXXXXXXXXXVRFIEKLADQTDSQINEANNILQKRR----DEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL-KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQE------ILQTIDEINSKN--ISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTY----PQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNK-LPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDI 1750
            +W  + LV    V+GV   Y +  + K  + +   +  E  A     +  EA     +      D A   K KGN++F    +ENAI+ Y  AI++CP +   D +  Y+N+A A  +    AE + +  +A+E+ P+Y  A   R+K  E L   +E L D+TA    ++     S+   D ++K +  E+ KE+   +EP++ S + I  YF +F DD     L    +  E+  +     ++  +  Y    Q ++E      I +   EI S     ++  LLR TFYLL      A  D  RVI  P++    + NA+IKR ++ + +   +   + F  A +I+    D+++HRG       Q   A+ DF + + L  +  LA     F  Y   Y    P   ++  D FE++I+  P  +E   +Y + L        A+ + DK + ++ D+ +       ++  + + L   L L+ +AIE D K   +Y  +  I ++ G L++AIEM  KAI  A++   M     + +   AQ  V+R + +
Sbjct:   17 RWQLALLVGTPIVLGVGAVYLWNRRAKERKRTGERKTPEGSASPVQGKDGEARTNRDQENMSPLDRAQAAKNKGNKYFKATKYENAIQCYTEAISLCPKEQKADLSTFYQNRAAAYEQQMKWAEVVQDCTQAVELNPRYIKALFRRAKALEKLDNKKECLEDVTAVCILEAFQNQQSMLLADKVLKQLGKEKAKEKYKNREPMMPSPQFIKSYFSSFTDDIISQPLQKGEKKDEDKDNEGEAAQVTESSGYLKAKQYMEEENYDKIISECTKEIESGGRYTAEALLLRATFYLLIGNATAAQPDLDRVINLPDANVKLQANALIKRGSMYMQQQQPVLSTQDFNTAAEIDKRNPDVYHHRGQLKILLDQVDDAVADFDECILLRPDSALAQAQKCFALYRQAYTGNNPTRVQTAMDGFEDVIRRFPKCAEGYALYAQALTDQQQFGKADEMYDKCIELEPDNATTYVHKGLLQLQWKQDLDLGLDLISKAIEIDNKCDFAYETMGTIEVQRGNLDRAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVARKYGL 572

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Planmine SMEST
Match: SMESG000070025.1 (SMESG000070025.1)

HSP 1 Score: 1049.65 bits (2713), Expect = 0.000e+0
Identity = 554/558 (99.28%), Postives = 556/558 (99.64%), Query Frame = 2

Query:  119 MDNKLPSIKWITSTLVLVATVIGVYYFYXXXXXXXXXXXXVRFIEKLADQTDSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEILKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQGKI 1792
            MDNKLPSIKWITSTLVLVATVIGVYYFYKNKNKNNQTSNNVRFIEKLADQTDSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYRNKALALNRLENNAEALNEVNKALEILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEI+KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYS CFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIEN NSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCAD+FYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQGKI
Sbjct:    1 MDNKLPSIKWITSTLVLVATVIGVYYFYKNKNKNNQTSNNVRFIEKLADQTDSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYRNKALALNRLENNAEALNEVNKALEILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIMKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSTCFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENSNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADIFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQGKI 558

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Planmine SMEST
Match: SMESG000070017.1 (SMESG000070017.1)

HSP 1 Score: 364.77 bits (935), Expect = 1.818e-118
Identity = 219/570 (38.42%), Postives = 348/570 (61.05%), Query Frame = 2

Query:  119 MDNKLPSIKWITSTLV---LVATVIGVYYFYXXXXXXXXXXXXVRFIEKLADQTDSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEILKEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAGQYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSRVIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLFYHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHGKSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRDSGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTGELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVIRHVSQGKI*LDMESHFF 1819
            M N    + W T+ +V      T +G+YY+  ++ K+              D  D+QI   +   +   DEA  +K KGN  +    +E+AI+ Y  A+N CP    +D A++Y+N+A+A   L+   +AL ++N+AL + P+Y  A   RSK++E  GK +EAL DITAA  F+    S+ + RM+ IVKNIA   V++E+   P L S+  I+ YF++F +DP  ++ +    D   +  +SRC +L  +  Y   F+ VQ +L+   ++N + +S+L LLRGTF+LLSCREELAL+DF++VI N  +KPS  VNA+IKRA I++  +N+  +++ F EAL I+P+C D++YHRG F E   + + A++DF +ALE N+ +  A+VH VFN+  ++     ++ F++F+NLI+  PN  E   ++ +VL+  G  D AE +   LL+    SG++M  +A IK   NK+ EA  +L   I++DP+ + SY  LA I IK G+L+KA+E+L++A+K+ARNRQ M+ +I  +EG  AQLNVS  ++IP +++   + QG   LDM + + 
Sbjct:    1 MQNNNSHLNWKTAAIVGAIAATTSVGIYYYLHSRKKSINI-----------DNVDAQI-LPDLTYRNPLDEAKRLKEKGNLHYKGGQYESAIQCYTNALNTCPSDSKQDKAMMYQNRAVAYENLKEYDKALLDLNEALVLHPKYEKALIRRSKMYEEQGKFREALIDITAASIFNRFRISELMSRMEQIVKNIAKIEVEKELTGPPTLQSDLYISTYFESFPNDPLLNASD----DEAGDNDVSRCFELLKSKNYEESFKAVQNVLREKQDLNDEVMSRLLLLRGTFFLLSCREELALEDFAKVINNSYAKPSVTVNALIKRAMIMIINDNAPEVDKAFTEALQIDPDCPDIYYHRGSFFESVERVQEAVNDFSRALEQNANYSFAAVHKVFNQSRMS--TSNQNIFEEFKNLIKRFPNCVECNIIFAQVLLSEGRTDEAEKVCGDLLMNQLKSGTIMATLAMIKLSQNKILEARRVLNETIKEDPRCSYSYNTLATIFIKEGDLQKALELLDQAVKFARNRQEMQNFIATREGVRAQLNVSVNYNIPPREIFEAILQG---LDMPAAYM 549

[Close]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Planmine SMEST
Match: SMESG000055125.1 (SMESG000055125.1)

HSP 1 Score: 55.0694 bits (131), Expect = 7.640e-8
Identity = 57/180 (31.67%), Postives = 96/180 (53.33%), Query Frame = 2

Query:  314 RDEALLIKIKGNEFFNLNDFENAIKQYEMAINICPLQFIRDHAVLYXXXXXXXXXXXXXXXXXXXXXXXXXILPQYPTAFDTRSKIFETLGKLQEALFDITAAVTFDSTDKSD--SVDRMDNIVKNIAIERVKEEILKE----------PVLISEKEITKYFKAFIDDPFPSSLNIDIQD 817
            ++++L +K +GN  F L  ++ AI+ Y  AI+ CPLQF  +HA+ + N+   L +L  N EA+N+++ A+++ PQY  A   R+++ E   KL EAL D    +  D  + S   +V  +   +K I  E++KEE+  +          P  +S    T  FK  + DP   S +I+ Q+
Sbjct:  165 KEKSLYLKDQGNASFKLEQYDEAIEFYTNAISTCPLQFNEEHAIFHSNRGTTLAKLVKNEEAINDLSIAIKLKPQYLKALVRRAELREKTEKLSEALEDYQEILKIDPKNWSALYAVQTLPEKIK-IQQEKMKEEMFTQLKQLGNLVLKPFGLS----TDNFK-MVQDPATGSYSINFQN 338

The following BLAST results are available for this feature:

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Human
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Celegans
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Fly
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Zebrafish
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Xenopus
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Mouse
BLAST of Mitochondrial import receptor subunit TOM70 vs. UniProt/SwissProt
BLAST of Mitochondrial import receptor subunit TOM70 vs. TrEMBL
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Cavefish
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Sea Lamprey
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Yeast
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Nematostella
BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Medaka
BLAST of Mitochondrial import receptor subunit TOM70 vs. Planmine SMEST

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3


Match Name	E-value	Identity	Description
TOMM70	1.661e-40	27.44	translocase of outer mitochondrial membrane 70 [So...	[more]
TTC1	7.882e-7	31.43	tetratricopeptide repeat domain 1 [Source:HGNC Sym...	[more]
TTC1	7.882e-7	31.43	tetratricopeptide repeat domain 1 [Source:HGNC Sym...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tom70	3.220e-32	24.56	gene:FBgn0032397 transcript:FBtr0080310	[more]
Tom70	3.220e-32	24.56	gene:FBgn0032397 transcript:FBtr0080309	[more]
Tom70	3.220e-32	24.56	gene:FBgn0032397 transcript:FBtr0080311	[more]
CG14894	7.791e-7	36.94	gene:FBgn0038428 transcript:FBtr0083314	[more]
CG14894	7.791e-7	36.94	gene:FBgn0038428 transcript:FBtr0337016	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
tomm70a	7.707e-40	26.03	translocase of outer mitochondrial membrane 70 hom...	[more]
tomm70a	7.707e-40	26.03	translocase of outer mitochondrial membrane 70 hom...	[more]
ttc1	9.045e-6	31.82	tetratricopeptide repeat domain 1 [Source:ZFIN;Acc...	[more]
ttc1	9.701e-6	31.82	tetratricopeptide repeat domain 1 [Source:ZFIN;Acc...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tomm70	8.995e-41	27.54	translocase of outer mitochondrial membrane 70 [So...	[more]
tomm70	1.430e-40	27.44	translocase of outer mitochondrial membrane 70 [So...	[more]
tomm70	2.742e-40	27.09	translocase of outer mitochondrial membrane 70 [So...	[more]
tomm70	6.903e-40	27.44	translocase of outer mitochondrial membrane 70 [So...	[more]
tomm70	7.269e-40	27.04	translocase of outer mitochondrial membrane 70 [So...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Tomm70a	2.284e-37	26.63	translocase of outer mitochondrial membrane 70A [S...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O94826\|TOM70_HUMAN	7.976e-40	27.44	Mitochondrial import receptor subunit TOM70 OS=Hom...	[more]
sp\|Q75Q39\|TOM70_RAT	1.524e-36	26.63	Mitochondrial import receptor subunit TOM70 OS=Rat...	[more]
sp\|Q9CZW5\|TOM70_MOUSE	1.597e-36	26.63	Mitochondrial import receptor subunit TOM70 OS=Mus...	[more]
sp\|P23231\|TOM70_NEUCR	1.480e-22	24.19	Mitochondrial import receptor subunit tom70 OS=Neu...	[more]
sp\|O14217\|TOM70_SCHPO	1.352e-21	24.09	Probable mitochondrial import receptor subunit tom...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1J1HIM9	4.644e-51	28.08	CLUMA_CG000014, isoform A OS=Clunio marinus OX=568...	[more]
A0A0N1PKE8	1.364e-46	28.52	Mitochondrial import receptor subunit TOM70 OS=Pap...	[more]
A0A194PI34	5.735e-45	28.34	Mitochondrial import receptor subunit TOM70 OS=Pap...	[more]
A0A232FEY5	1.304e-44	27.18	Uncharacterized protein OS=Trichomalopsis sarcopha...	[more]
A0A553PL71	1.675e-43	26.76	Uncharacterized protein OS=Tigriopus californicus ...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
tomm70a	1.646e-40	26.63	translocase of outer mitochondrial membrane 70 [So...	[more]
tomm70a	2.164e-32	26.01	translocase of outer mitochondrial membrane 70 [So...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ttc1	3.474e-10	28.04	tetratricopeptide repeat domain 1 [Source:ZFIN;Acc...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
TOM70	9.530e-14	23.52	Component of the TOM (translocase of outer membran...	[more]
TOM71	1.284e-13	24.70	Mitochondrial outer membrane protein; probable min...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO45236	1.923e-35	25.35	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28351	1.142e-8	25.56	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
tomm70a	4.433e-44	26.44	translocase of outer mitochondrial membrane 70 [So...	[more]

BLAST of Mitochondrial import receptor subunit TOM70 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000070025.1	0.000e+0	99.28	SMESG000070025.1	[more]
SMESG000070017.1	1.818e-118	38.42	SMESG000070017.1	[more]
SMESG000055125.1	7.640e-8	31.67	SMESG000055125.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30015700 ID=SMED30015700|Name=Mitochondrial import receptor subunit TOM70|organism=Schmidtea mediterranea sexual|type=transcript|length=1970bp
TTTTTAGAAAATTGTTTAACTAACATTATTTAACAAATATTTTTAAAACT
TTTGTTAAATTGTTAAGTAACAAATTTAAAACATATTTTTTCCTTATAAA
ATTAGAACAATATATTAAATGGATAATAAACTTCCGAGTATTAAATGGAT
AACCAGCACTCTTGTATTGGTTGCTACTGTAATTGGAGTATATTATTTTT
ATAAAAATAAAAATAAAAATAATCAAACATCGAATAATGTGAGATTTATT
GAGAAACTTGCTGATCAAACTGATAGTCAAATTAATGAAGCAAACAACAT
TTTACAAAAAAGACGCGATGAGGCATTATTAATAAAGATTAAAGGAAATG
AGTTTTTCAATTTAAATGATTTTGAAAATGCTATAAAACAATACGAAATG
GCAATAAATATTTGTCCTTTGCAATTTATTCGCGATCATGCGGTATTATA
TCGAAATAAAGCGCTAGCTTTAAATCGGCTAGAAAATAATGCTGAAGCTT
TAAATGAAGTTAATAAAGCCTTGGAAATTTTACCGCAATATCCAACTGCT
TTTGATACAAGATCTAAAATTTTTGAAACTTTAGGAAAACTTCAAGAAGC
TTTATTTGATATTACAGCAGCTGTAACTTTTGATAGCACTGATAAATCCG
ACTCAGTCGATCGCATGGATAATATAGTTAAAAACATTGCAATTGAAAGA
GTCAAAGAAGAAATTTTGAAAGAGCCTGTGTTGATTTCTGAAAAGGAAAT
TACAAAGTATTTCAAGGCTTTTATAGACGATCCATTTCCAAGTTCTTTAA
ACATTGATATACAAGATTCAGAAAATAATCAGTCTTTATCCCGATGCATA
AAATTGTTTATAGCTGGTCAATATTCGGCCTGTTTTCAACAAGTTCAAGA
AATTCTTCAAACTATTGATGAAATCAACAGTAAAAACATTAGCCAATTGC
ACCTTCTTAGAGGCACATTTTATCTGTTAAGCTGCAGGGAAGAATTAGCT
TTAAAAGATTTCTCTCGAGTTATCGAGAATCCAAATTCAAAACCTTCGGA
AAAAGTTAACGCTGTTATTAAACGTGCAACAATTTTGCTGACGGAAAATA
ACTCGTTAAATATCGAAGAAGTTTTTAAAGAAGCCCTTGATATAAATCCG
AATTGCGCTGATCTTTTTTACCATCGTGGTCTTTTTCATGAACAATCCGG
ACAATATAAAGCGGCTATTGATGATTTCCAAAAAGCTCTAGAGTTAAACT
CGGAACATTTGCTGGCCTCTGTTCACAATGTGTTCAATGAGTATTGGCTG
ACTTATCCGCAGCACGGAAAATCGTGTTTTGATCAATTTGAAAACCTTAT
ACAGACCCATCCGAACTCCAGTGAAGTTCAGCAGATGTATATCAAGGTGT
TGATGCATTCTGGCCACTGTGACCTGGCTGAAAACATAGTGGACAAATTG
CTTCTCATAGACCGAGATTCCGGTTCGGTAATGAATTTCATTGCCGACAT
TAAATTCCTCTTCAATAAGCTGCCGGAAGCACTCGCACTTCTCGAGCGAG
CTATTGAGAAAGATCCGAAACACGCAGATTCTTATTATTTGTTGGCTGTG
ATCTTGATTAAAACCGGTGAACTGGAGAAGGCGATTGAAATGTTAGAAAA
GGCAATAAAATATGCAAGAAATCGTCAGACCATGAGAAAGTATATTGAGA
TTAAGGAGGGTTTTGCGGCGCAATTGAATGTGTCGAGGACGTTTGATATT
CCCATAAAAGATGTGATTCGCCACGTATCTCAAGGGAAAATCTGATTGGA
TATGGAAAGTCATTTTTTTCGACCTCATTTGTTTTGAGAGTTTTCTGATT
GCTTTATTTTTATATATTGATTTTTATTTCTCCCTCATGTGAGTACGGAT
CAAGGATCCACCGCTCTGGTGCCATTGGTGGATTTTTGATTCGATCGCTT
TTTTTATTATTATTGTCTTG

protein sequence of SMED30015700-orf-1

>SMED30015700-orf-1 ID=SMED30015700-orf-1|Name=SMED30015700-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=559bp
MDNKLPSIKWITSTLVLVATVIGVYYFYKNKNKNNQTSNNVRFIEKLADQ
TDSQINEANNILQKRRDEALLIKIKGNEFFNLNDFENAIKQYEMAINICP
LQFIRDHAVLYRNKALALNRLENNAEALNEVNKALEILPQYPTAFDTRSK
IFETLGKLQEALFDITAAVTFDSTDKSDSVDRMDNIVKNIAIERVKEEIL
KEPVLISEKEITKYFKAFIDDPFPSSLNIDIQDSENNQSLSRCIKLFIAG
QYSACFQQVQEILQTIDEINSKNISQLHLLRGTFYLLSCREELALKDFSR
VIENPNSKPSEKVNAVIKRATILLTENNSLNIEEVFKEALDINPNCADLF
YHRGLFHEQSGQYKAAIDDFQKALELNSEHLLASVHNVFNEYWLTYPQHG
KSCFDQFENLIQTHPNSSEVQQMYIKVLMHSGHCDLAENIVDKLLLIDRD
SGSVMNFIADIKFLFNKLPEALALLERAIEKDPKHADSYYLLAVILIKTG
ELEKAIEMLEKAIKYARNRQTMRKYIEIKEGFAAQLNVSRTFDIPIKDVI
RHVSQGKI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR019734	TPR_repeat
IPR001440	TPR_1
IPR011990	TPR-like_helical_dom_sf
IPR013026	TPR-contain_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0006396	RNA processing

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 111..138
None	No IPR available	PFAM	PF14559	TPR_19	coord: 468..519 e-value: 3.7E-11 score: 43.4
None	No IPR available	PANTHER	PTHR46208	FAMILY NOT NAMED	coord: 13..542
None	No IPR available	TMHMM	TMhelix		coord: 10..28
IPR019734	Tetratricopeptide repeat	SMART	SM00028	tpr_5	coord: 313..346 e-value: 280.0 score: 2.2 coord: 275..308 e-value: 32.0 score: 10.6 coord: 69..102 e-value: 0.46 score: 19.5 coord: 452..485 e-value: 4.3 score: 16.3 coord: 108..141 e-value: 0.42 score: 19.7 coord: 347..380 e-value: 1.7E-7 score: 40.9 coord: 486..519 e-value: 1.5E-4 score: 31.1 coord: 142..175 e-value: 100.0 score: 6.2
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 108..141 score: 7.67
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 142..175 score: 5.428
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 275..308 score: 5.9
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 313..346 score: 6.284
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 69..102 score: 8.585
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 486..519 score: 10.207
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 347..380 score: 12.154
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 452..485 score: 7.287
IPR011990	Tetratricopeptide-like helical domain superfamily	GENE3D	G3DSA:1.25.40.10		coord: 61..179 e-value: 3.5E-22 score: 80.6
IPR011990	Tetratricopeptide-like helical domain superfamily	GENE3D	G3DSA:1.25.40.10		coord: 180..543 e-value: 6.0E-51 score: 175.6
IPR011990	Tetratricopeptide-like helical domain superfamily	SUPERFAMILY	SSF48452	TPR-like	coord: 60..175
IPR011990	Tetratricopeptide-like helical domain superfamily	SUPERFAMILY	SSF48452	TPR-like	coord: 281..518
IPR001440	Tetratricopeptide repeat 1	PFAM	PF00515	TPR_1	coord: 347..379 e-value: 3.8E-8 score: 32.8
IPR013026	Tetratricopeptide repeat-containing domain	PROSITE	PS50293	TPR_REGION	coord: 275..519 score: 31.223
IPR013026	Tetratricopeptide repeat-containing domain	PROSITE	PS50293	TPR_REGION	coord: 69..175 score: 16.436

Main menu

Mitochondrial import receptor subunit TOM70

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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